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Trans-11-Octadecenoic Acid

    • Product Name Trans-11-Octadecenoic Acid
    • Alias Vaccenic Acid
    • Einecs 217-234-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    297474

    Cas Number trans-11-Octadecenoic acid
    Molecular Formula C18H34O2
    Molecular Weight 282.47 g/mol
    Iupac Name (E)-Octadec-11-enoic acid
    Common Name Vaccenic acid
    Appearance White to off-white solid
    Melting Point 41-43°C
    Boiling Point ~230°C at 10 mmHg
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in ethanol, chloroform, and ether
    Density 0.90 g/cm³ (at 20°C)
    Chemical Class Unsaturated fatty acid
    Structure Type Trans-monounsaturated
    Double Bond Position 11th carbon (trans configuration)

    As an accredited Trans-11-Octadecenoic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Trans-11-Octadecenoic Acid, 5g, packaged in a sealed amber glass bottle with screw cap; clearly labeled with hazard and handling information.
    Shipping Trans-11-Octadecenoic Acid is shipped in tightly sealed containers, protected from light, heat, and moisture. It is packed in compliance with relevant chemical handling and safety guidelines, ensuring safe transit. Appropriate labeling, documentation, and hazard information accompany the shipment for regulatory compliance and safe handling during transportation and delivery.
    Storage Trans-11-Octadecenoic acid should be stored in a cool, dry, and well-ventilated area, away from direct sunlight and sources of heat or ignition. Keep the container tightly closed when not in use. Store separately from oxidizing agents and strong acids. Use appropriate, labeled containers to prevent contamination and degradation. Ensure that storage complies with all relevant chemical safety guidelines.
    Application of Trans-11-Octadecenoic Acid

    Applications of Trans-11-Octadecenoic Acid in Industrial Manufacturing

    Trans-11-Octadecenoic Acid (Vaccenic Acid) serves specialized roles in industrial production. We manufacture this fatty acid to address exacting standards in food processing, nutrition, cosmetics, specialty lubricants, and pharmaceutical intermediates. The following scenarios detail industry-specific applications, compliance frameworks, formulation approaches, integration methods, and real downstream product types.

    1. Nutritional Supplement and Functional Food Fortification

    Nutritional product manufacturers incorporate vaccenic acid as a beneficial trans-monounsaturated fatty acid to develop functional foods and dietary supplements, particularly those targeting cardiovascular health. It appears in structured triglyceride formulations, dairy analogues, and encapsulated oils. Product developers base inclusion levels on regulatory maximums and nutritional safety data, adjusting formulation ratios for optimal fatty acid profiles. Typical processing requires precise blending at controlled temperatures to retain geometric isomer structure. Downstream producers combine with omega-3 and omega-6 fatty acids to create fatty acid supplements, nutritional bars, or value-added dairy items.

    Industry compliance standards

    • European Food Safety Authority (EFSA) trans fat regulations
    • US FDA Generally Recognized as Safe (GRAS) for food ingredients
    • Regulation (EC) No 1925/2006 (EU addition of nutrients)
    • ISO 22000 Food Safety Management System

    Typical usage ratio

    • 0.1% - 1% by weight in finished foods; manufacturers adjust within legal trans fat limits per region.

    Downstream process integration

    • Added to oil phase during emulsion preparation or directly to melted fats for margarine, spreads, or nutritional blends.

    Final product types

    • Fortified edible oils
    • Functional dairy alternatives
    • Dietary supplements in softgel capsules
    • Meal replacement bars

    2. Pharmaceutical Intermediates and API Synthesis

    Chemical synthesis facilities select this fatty acid as a chiral precursor and intermediate for specific pharmaceutical formulations, such as lipid-based delivery systems and modified cyclodextrins. Research teams rely on its defined cis/trans isomerism to construct molecules with bioactive properties, particularly in metabolic disease targets. Production adheres to GMP environments, requiring traceable sourcing, process validation, and full batch documentation. Its input ratio in esterification and amidation reactions depends on stoichiometric balances defined in process development protocols.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • United States Pharmacopeia-National Formulary (USP-NF)
    • EU GMP Directive 2017/1572
    • Certificate of Analysis per Ph.Eur or JP as required

    Typical usage ratio

    • 0.2 molar equivalents to 2 molar equivalents, based on desired output purity and target compound structure.

    Downstream process integration

    • Introduced at the initial ester synthesis stage, monitored through GC/HPLC to ensure isomeric purity before progressing to further transformations.

    Final product types

    • Lipid-based injectable excipients
    • Modified cyclodextrin carriers
    • Biologically active fatty acid derivatives
    • Intermediate active pharmaceutical ingredients (APIs)

    3. Cosmetic Emollients and Skin Conditioning Agents

    Personal care formulators utilize vaccenic acid for its skin-conditioning and emollient properties in creams, lotions, and specialty dermatological products. Its molecular structure offers desired spreadability and skin-feel. Our production delivers low peroxide and low acidity grades to meet high-end cosmetic and cosmeceutical requirements. Product safety approvals require REACH registration and compliance with specific regional cosmetic directives. The concentration in emulsions varies depending on product viscosity and desired occlusivity, adjusted during pilot batching and stability trials.

    Industry compliance standards

    • Regulation (EC) No 1223/2009 on cosmetic products
    • REACH Registration (EC 1907/2006)
    • ISO 22716 Cosmetics GMP
    • US FDA Voluntary Cosmetic Registration Program (VCRP)

    Typical usage ratio

    • 0.5% – 3% by weight in oil phases; levels vary for leave-on products versus wash-off applications.

    Downstream process integration

    • Integrated into the oil phase during early emulsion creation steps; undergoes chilling and vacuum homogenization to preserve emollient properties.

    Final product types

    • Facial creams
    • Rich body lotions
    • Moisturizing ointments
    • Cosmeceutical boosters (anti-aging formulas)

    4. Lubricant and Grease Formulation for Food Contact Machinery

    Industrial formulators add vaccenic acid to tailor the tribological properties of specialty greases and lubricants for use in food processing equipment. This application requires compliance with strict food contact regulations to guarantee purity and low toxicity. Blenders incorporate vaccenic acid into complex esters and calcium/lithium soap-based thickeners. Effective incorporation assists in adjusting low-temperature operability and oxidation stability. Finished greases must undergo rigorous migration and stability testing before deployment on production lines.

    Industry compliance standards

    • NSF International H1 (lubricants with incidental food contact)
    • 21 CFR 178.3570 (USDA/FDA food-grade lubricants)
    • ISO 21469 Hygiene requirements for lubricants
    • Halal/Kosher certificates for food plant compliance as required

    Typical usage ratio

    • 1% – 10% by total base oil weight, modified according to target viscosity and drop-point specifications based on machinery operating conditions.

    Downstream process integration

    • Introduced during thickener saponification, then post-blended to adjust lubricity in final grease compounding phases.

    Final product types

    • Food machinery bearing greases
    • Chain lubricants used in oven conveyors
    • Anticorrosive specialty oils for food-grade environments
    • White mineral-based greases

    5. Surface-Active Agent and Emulsifier Synthesis

    Specialty surfactants manufacturers leverage vaccenic acid as a key reactive fatty acid in the production of emulsifiers intended for food, pharmaceutical, and personal care applications. The unsaturated structure lends itself to controlled functionalization via ethoxylation, sulfonation, or glycerolysis. Process engineers maintain reaction temperatures and inert atmospheres to minimize geometric isomerization. Compliance requirements dictate traceability from raw material through to the finished surfactant, with full regulatory support for downstream use in consumables and topical products.

    Industry compliance standards

    • 21 CFR 172.515 (food additive emulsifiers, US FDA)
    • China GB 2760 - Food Additive Standards
    • ISO 9001 Quality Management for surfactant manufacture
    • IFRA Standards for personal care surface actives

    Typical usage ratio

    • 10% – 25% by reactant charge, with the ratio determined by the desired HLB balance and target application (e.g. food vs. pharma emulsifiers).

    Downstream process integration

    • Charged to reactor as the main fatty acid input, functionalized via alkoxylation or condensation, then neutralized and spray dried (if solid surfactant is final goal).

    Final product types

    • Food emulsifying agents (e.g. mono-/di-glycerides)
    • Dispersants for pharmaceutical suspensions
    • Skin-friendly surfactants for cream/lotion production
    • Bakery dough improvers
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    Certification & Compliance
    More Introduction

    Trans-11-Octadecenoic Acid: Practical Insights from the Manufacturer

    What Is Trans-11-Octadecenoic Acid?

    Trans-11-Octadecenoic Acid, often called vaccenic acid, holds a recognized position in fatty acid chemistry. Produced every day at our plant from select natural feedstocks, this mono-unsaturated fatty acid brings a C18:1 carbon chain with a double bond at the 11th position in the trans configuration. The chemical structure gives it distinct behavior in both industrial and biological settings. Unlike resellers, we oversee each step, monitoring purity with modern chromatography and gas analysis. Reliable consistency comes from decades refining process conditions and raw material selection.

    How We Manufacture Vaccenic Acid

    Experience with fats and oils sets the basis for every batch we make. Our sourcing focuses on ruminant-derived fats and specialty plant oils. Once the raw material reaches our site, careful hydrolysis and fractionation extracts the acid. Purification and controlled hydrogenation ensure a targeted isomer ratio, minimizing cis-isomers and other fatty acids. Quality control hinges on IR spectroscopy and gas capillary column chromatography. Every shipment undergoes these checks, confirming both geometric and positional purity of the double bond.

    Over years, we have found some practical limits: you can only push purity so far before cost and technical hurdles outweigh benefits. So, we offer grades optimized for different uses – food, pharma, feed, and research – based on real demand and regulatory needs, not just what looks impressive on a certificate.

    Why Purity and Isomer Ratio Matter

    In chemical manufacturing, even small shifts in isomer ratio or contaminant profile alter downstream outcomes. We’ve seen this firsthand in both polymer synthesis and nutritional supplement production. Certain applications, like pharmaceutical analysis or biological assay work, demand razor-sharp separation between trans-11 and other octadecenoic acids, especially cis-9 (oleic acid) and trans-9. Modest contamination, sometimes as little as one percent, leads to misleading assay results or undesired material properties. We maintain separate production lines for trans-rich and cis-rich grades, keeping cross-contamination close to undetectable with our detection equipment.

    Working directly with food technologists, our team learned most plant-extracted grades carry higher levels of cis-isomers and less stringent contaminant controls. Animal-based extraction, while more resource-intensive, produces the trans-11 predominance many clients need. That nuance often gets lost with generic bulk suppliers.

    Comparison With Other Octadecenoic Acids

    The C18:1 family contains several isomers, but not all behave the same in end-use. Oleic acid (cis-9-octadecenoic acid) dominates vegetable oils and draws attention for heart-health claims. Elaidic acid (trans-9-octadecenoic acid), often industrially generated during hydrogenation, is less common in nature and has different metabolic outcomes.

    Vaccenic acid's niche comes from its trans double bond at the 11th position, a position gaining scientific interest for distinct metabolic pathways. For scientists probing bioactive fats, this spatial difference drives interest. In industrial chemistry, the melting point and crystallization traits of trans-11 diverge from both oleic and elaidic acids, changing how the acid interacts with solvents, bases, and return yields in esterification or polymerization. Technicians blending specialty lubricants turn to trans-11 grades to control cold flow, or to fine-tune physical properties where even modest differences matter.

    Some users new to fatty acid sourcing ask why not substitute with generic “oleic” preparations or mixed C18:1 stocks. In our work, this route introduces inconsistency: reaction rates change, product textures drift, and in regulated spaces like food and pharma, tight labeling rules make shortcuts a liability. For those requiring well-defined trans isomers with dependable supply, a targeted trans-11 product avoids downstream headaches.

    Industrial and Research Applications of Trans-11-Octadecenoic Acid

    Demand appears strongest from four categories: academic researchers, supplement or food developers, specialty chemical formulators, and feed manufacturers. Academic teams pursue pure trans-11 samples for in vitro and clinical metabolic research. Our partnership with labs guides our batch design: small-run high-purity, unblended with lower-purity lots. Feedback from researchers taught us to avoid stabilizer additives and to supply shipping under nitrogen, so samples keep integrity for biological work.

    Food and nutraceutical developers approach us for grades compatible with labeling standards and stable under standard production. During development runs with R&D teams, we noticed that trans-11 behaves differently during heating and emulsification compared with its positional isomers. The right grade reduces off-odors and flavor issues, especially when used in functional dairy-alternative and meat-alternative product lines.

    For chemical manufacturers, the acid’s double bond location provides unique reactivity patterns. We’ve worked with polymer companies exploring bio-based alternatives, and lubricant firms tuning pour points. Trans-11 grades showed consistent performance, improving batch-to-batch reliability.

    Feed manufacturers benefit by including vaccenic acid in custom livestock rations, especially for ruminant animals. In this market, traceability and avoidance of unwanted trans-9 isomer content matter, especially when complying with consumer demand and export requirements. By offering full batch traceability and reports based on our analytical work, we help build long-term relationships within this segment.

    Quality Assurance That Shapes the Market

    Supplying chemical and food segments brings strict testing. Our in-house lab runs GC-MS and FTIR on every lot, comparing signatures to authenticated standards. Over the years, we’ve caught impurity patterns many competitors overlook: thermal isomerization during transport, residual solvents sneaking in from early-stage extraction, or oxidative degradation after partial container opening.

    We invest in tailored containers and shipping practices: argon-flushed drums for long-haul export, opaque HDPE for domestic transport. Regular returns from clients for reanalysis prompted us to add post-delivery testing, confirming the product stays within spec after extended storage. These extra steps cost more, but we see fewer returns and higher long-term demand as a result.

    Differences Between Model Grades and Market Impacts

    Trans-11-Octadecenoic Acid comes in several grades depending on end-use. For our food and feed clients, specifications reflect residue limits for pesticides, PCBs, and metals, as well as compliance with EU and US dietary standards. Pharma clients lean towards higher purity, often above 99 percent trans-11 as determined by area under chromatography curves, with full micro and metal reports. Technical and industrial clients seek reliability, with slightly lower purity tolerable if price and reactivity remain stable.

    Unlike some sellers who bulk blend or white-label, our process relies on single-source tracing for each batch. Over time, single-sourcing proved essential in dealing with regulatory reporting and customer inquiries regarding allergens or genetic origins.

    Many new entrants into this market launch with standardized “spec sheets,” but rarely control processes tightly enough to resolve customer complaints quickly. We document adjustment records for each batch: temperature profiles, feedstock analysis, analytical outcomes. This transparency allows for quick troubleshooting, which matters when one unexpected out-of-spec shipment can grind production to a halt.

    Trends in Use and Regulation

    Demand has shifted over time, driven partly by regulatory focus and evolving science. A decade back, most buyers wanted bulk C18:1 in whatever ratio was cheapest. Now, food-labeling laws and growing research distinguish between natural and synthetic fatty acids, and demand more accurate labeling for trans content.

    Nutrition research raises questions about metabolic differences among C18:1 isomers. This places real-world pressure on suppliers to deliver well-differentiated products, with transparent labeling and analytical backup. We’ve changed our own workflows over the years in direct response to this. In the industrial sector, performance requirements and environmental standards encourage rethinking sourcing, especially as more clients want renewable or upcycled feedstocks verified through audits.

    Our approach combines customer education with technical support. For instance, we share our best practices on handling and storage, and work collaboratively to select grade and packaging to fit the end-use, whether food, supplement, or synthesizing intermediates. These details allow users to extract the most value while managing technical complications that the wrong isomer mix or storage mistake can introduce.

    Challenges and Solutions in Production

    No manufacturing workflow escapes challenges. Over the past few years, supply-side volatility in raw fats and oils put pressure on cost and availability. Maintaining strict quality during these swings means developing relationships with multiple trusted suppliers and running extra analytics on inbound material.

    Temperature swings and humidity during shipping can alter fatty acid profiles subtly but significantly. We design supply chains to minimize transit time, pack under inert gases, and run spot checks on received product. These extra steps keep both performance and regulatory values consistent across the lifecycle.

    Energy costs impact large-scale production. Each lot takes time, electricity, and technical oversight. We use process automation where feasible, but keep key operations technician-assisted; automated monitoring flags outliers, but hands-on experience solves nuanced problems, like extraction tank fouling or gas-line leaks.

    Sometimes regulatory requirements change mid-year, impacting what clients need. Working as a primary manufacturer, we adapt quickly. With in-plant technical staff, new protocols or documentation emerge faster than in a decentralized distributor model. This speeds compliance and supports clients in their own filings and audits.

    Feedback Loop: What We Learn from Working With Direct Users

    Direct customer interaction shapes how we evolve our product. For instance, nutraceutical R&D teams asked for calibrated reference lots tailored for pilot-scale trials, so we set aside smaller containers for rapid deployment, reducing delays and duplicate shipping. Chemists from industries as varied as polymers and specialty lubricants pointed out where intermediates with minimal oxidized residue improved performance consistency—this feedback led us to tweak our vacuum stripping stages.

    Some of the most useful changes in our product line trace back to simple conversations with users: modifying drum head connectors after a client pointed out spillage risks; switching to code-lot labeling for better batch recall tracking; even introducing printed analytical datasets with each order. The shift from basic, generic product delivery to a partnership model improved retention and word-of-mouth recommendations.

    Ongoing Development and Future Directions

    As manufacturers, we engage in constant incremental development rather than radical reinvention. New purification technologies and greener solvents come into practical use only after pilot-scale testing. We collaborate with universities and technology firms developing new applications for trans-11 isomers—whether as chemical intermediates in biopolymers or active components in food science. These relationships drive us to refine processes, not just for purity, but for overall sustainability.

    The move to renewable sourcing continues, propelled by customer and regulatory preference. Upcycled oils and traceable animal fats increasingly integrate into our supply chain. Each year, supplier audits and compositional checks expand, so we control risk and guarantee the product our end users expect.

    Summary: Direct Manufacturing Brings Distinct Advantages

    Years of dedicated focus on trans-11-octadecenoic acid result in a manufacturing operation that prizes clarity, stability, and responsiveness. Direct experience pulling product from extraction tank to analytical lab shapes every decision we make. We see the market shifting: demand grows for more traceable, reliable, and clearly defined fatty acid products, on top of the basic expectation of regulatory compliance and competitive pricing.

    Every process tweak, quality report, and client conversation factors into how we present, supply, and back up our product. Continuous improvement defines reality here, not just as a slogan but embedded in daily routines and long-term planning. Our commitment to ongoing learning and transparent practice benefits end users—whether developing the next generation of biobased products, researching biological functions, or improving food and feed formulations. The work isn’t static, and neither are we.