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(+)-Trans-1,2-Cyclohexanedicarboxylic Anhydride

    • Product Name (+)-Trans-1,2-Cyclohexanedicarboxylic Anhydride
    • Alias trans-1,2-Cyclohexanedicarboxylic anhydride
    • Einecs 221-517-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    141637

    Product Name (+)-Trans-1,2-Cyclohexanedicarboxylic Anhydride
    Cas Number 1076-97-7
    Molecular Formula C8H8O3
    Molecular Weight 152.15 g/mol
    Appearance White to off-white solid
    Melting Point 185-190°C
    Boiling Point Decomposes before boiling
    Solubility Slightly soluble in water; soluble in organic solvents
    Specific Rotation +123° (c=1, acetone)
    Purity Typically ≥98%
    Storage Conditions Store in a cool, dry place, tightly closed
    Synonyms (+)-trans-1,2-Cyclohexanedicarboxylic acid anhydride
    Chirality Chiral, enantiomerically pure (+)-isomer
    Hazard Statements May cause skin and eye irritation

    As an accredited (+)-Trans-1,2-Cyclohexanedicarboxylic Anhydride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 25 grams of (+)-Trans-1,2-Cyclohexanedicarboxylic Anhydride, sealed with a screw cap and safety label.
    Shipping (+)-Trans-1,2-Cyclohexanedicarboxylic Anhydride should be shipped in tightly sealed containers, protected from moisture and incompatible substances. Store and transport at room temperature, away from heat and sources of ignition. Follow all applicable regulations for shipping chemicals, including labeling and documentation for handling hazardous compounds. Use protective packaging to prevent leaks or spills.
    Storage Store **(+)-Trans-1,2-Cyclohexanedicarboxylic Anhydride** in a cool, dry, and well-ventilated area away from moisture and incompatible substances, such as strong bases or oxidizers. Keep the container tightly closed when not in use. Protect from humidity and direct sunlight. Recommended storage temperature is between 2-8°C (refrigerated). Always follow local regulations and material safety data sheet (MSDS) guidelines.
    Application of (+)-Trans-1,2-Cyclohexanedicarboxylic Anhydride

    Applications of (+)-Trans-1,2-Cyclohexanedicarboxylic Anhydride in Industrial Manufacturing

    (+)-Trans-1,2-Cyclohexanedicarboxylic Anhydride is a specialty intermediate widely used in select industrial sectors where cyclic anhydrides serve as fundamental components in advanced material synthesis. We focus on proven, high-value downstream applications where this material’s reactivity and chiral integrity enable manufacturers to meet rigorous product specifications through well-established technical processes.

    1. Curing Agent for High-Performance Epoxy Systems in Electronics Encapsulation

    Leading electronics manufacturers rely on this material as a tailored curing agent for encapsulation-grade epoxy resins, where precise anhydride structure delivers desired thermal properties and dimensional stability. The compound reacts during the resin blending and curing step, ensuring uniform polymer network formation, which is critical for devices exposed to thermal cycling.

    Industry compliance standards

    • UL 94 for flame resistance
    • IPC-4101 for base materials in printed wiring boards
    • RoHS Directive (2011/65/EU) for hazardous substances
    • ISO 9001 Quality Management Systems (certified users)

    Typical usage ratio

    • In epoxy formulations, typical usage ranges from 20% to 35% by weight relative to base resin, depending on viscosity, cure kinetics, and targeted glass transition temperature.

    Downstream process integration

    • Material is introduced during the resin pre-mix phase, commonly under controlled agitation at 60–80°C, followed by vacuum de-airing and thermal post-curing after molding or casting around electronic assemblies.

    Final product types

    • Epoxy-molded integrated circuit chips
    • Electronic encapsulants for automotive sensors
    • Power module protective shells
    • Relay coil pottings

    2. Intermediate for Synthesis of UV-Curable Oligomers in Industrial Coatings

    Industrial coatings producers employ (+)-Trans-1,2-Cyclohexanedicarboxylic Anhydride in the synthesis of UV-reactive oligomers for high-grade protective surfaces. Its ring structure introduces controlled flexibility and hydrophobicity into oligomer chains, improving film toughness and resistance to environmental stress.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 (substance registration and assessment)
    • ISO 12944-6 for corrosion protection coatings
    • Directive 2004/42/EC on VOC emissions in paints and varnishes
    • ISO 14001 Environmental Management (certified production lines)

    Typical usage ratio

    • In oligomer synthesis, incorporation varies from 10% to 20% molar basis, adjusted to tune film flexibility versus crosslink density for end-use demands.

    Downstream process integration

    • The anhydride is reacted with polyol or polyamine feedstock under catalyst and temperature control to form oligomer backbones. Post-reaction blending yields UV-curable varnish ready for downstream application.

    Final product types

    • Scratch-resistant wood and furniture coatings
    • Protective coatings for automotive plastics
    • Industrial floor finishes
    • Printed packaging overprint varnishes

    3. Synthesis of Polyimide Precursors for Advanced Thermal Insulation Films

    Producers of specialty polyimide films utilize (+)-Trans-1,2-Cyclohexanedicarboxylic Anhydride as a dianhydride monomeric building block. The compound delivers defined rigidity and thermal resistance to polyimide backbones crucial for flexible printed circuits and aerospace-grade insulation.

    Industry compliance standards

    • ASTM D5213 for polyimide film properties
    • IPC-4101/40 & IPC-4202 for flexible circuit materials
    • EN 45545-2 fire protection standard for railway applications
    • ISO 10993-5 for cytotoxicity in medical devices (where utilized in electronics)

    Typical usage ratio

    • In polyimide synthesis, usage typically spans 25% to 45% molar equivalent against chosen diamine monomers, with exact proportions governed by targeted film thickness, tensile strength, and flexibility parameters.

    Downstream process integration

    • Crude anhydride is dissolved in polar aprotic solvent, followed by stepwise addition of diamine monomer. After polyamic acid formation and imidization (thermal cure at 200–300°C), high-performance film is cast or extruded.

    Final product types

    • Flexible printed circuit substrates
    • High-temperature wire and cable wrap films
    • Insulation films for microelectronic and aerospace modules
    • Flexible heater elements

    4. Raw Material for Chiral Auxiliary Synthesis in Fine Chemicals

    Manufacturers engaged in optically active compound preparation adopt (+)-Trans-1,2-Cyclohexanedicarboxylic Anhydride as a high-purity chiral auxiliary due to its robust stereochemical control. Key in asymmetric catalysis, it supports the industrial-scale production of advanced agrochemical and pharmaceutical intermediates where consistent enantiopurity is non-negotiable.

    Industry compliance standards

    • Current Good Manufacturing Practice (cGMP, 21 CFR Part 210/211)
    • ICH Q7 for API manufacturing
    • Ph. Eur. 2.2.46: Chromatographic separation of enantiomers
    • ISO 17025 for in-house analytical labs

    Typical usage ratio

    • Employers typically use from 5% up to 22% molar ratio as auxiliary, calculated relative to the prochiral substrate and adjusted based on downstream reaction mechanism and recovery protocol.

    Downstream process integration

    • The anhydride is introduced at the start of asymmetric synthesis, combined with amines or alcohols under controlled conditions to induce chiral center formation. Post-reaction, spent auxiliary is recovered and purified for reuse.

    Final product types

    • Chiral pharmaceutical intermediates
    • Optically pure agrochemical actives
    • Custom fine chemicals for contract synthesis
    • Chemical building blocks for research-scale organocatalysis

    5. Modifier in Unsaturated Polyester Resin Production for Impact-Resistant Composites

    Factories producing impact-modified unsaturated polyester resins employ this anhydride to fine-tune crosslinking density and mechanical strength. By integrating its cyclic structure, formulators can reinforce composites for demanding load-bearing applications, optimizing for toughness without sacrificing processability.

    Industry compliance standards

    • EN 13501-1 reaction to fire classification (building products)
    • ASTM D638 tensile properties of plastics
    • ISO 9001 for formulated resin plants
    • REACH SVHC compliance declaration

    Typical usage ratio

    • The curing formulation incorporates from 8% to 16% by weight, based on total anhydride content required to balance impact resistance with desired heat deflection temperature.

    Downstream process integration

    • Operators add the anhydride to the resin synthesis reactor after ethylene glycol feed. Post-polymerization, resin blend is directly applied in closed-mold or open-mold composite fabrication.

    Final product types

    • Automotive body panels
    • Industrial structural profiles
    • Building façade sheets
    • Marine composite components
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    Certification & Compliance
    More Introduction

    Understanding (+)-Trans-1,2-Cyclohexanedicarboxylic Anhydride from a Manufacturer’s Perspective

    Real-World Insights Into (+)-Trans-1,2-Cyclohexanedicarboxylic Anhydride

    In the chemical industry, every compound brings its own unique fingerprint to the processes and products it touches. (+)-Trans-1,2-Cyclohexanedicarboxylic Anhydride stands out in that way most don’t. From where we’re working, you get a true sense of how the structure and selectivity of each molecule turn into practical benefits on the production floor, in the lab, or downstream in the value chain.

    This anhydride comes from cyclohexane, shaped by specific hydrogenation and oxidation steps. Producing it at scale means more than just getting yields or top-line purity. We pay close attention to the stereochemistry—this trans isomer influences both reactivity and the profile of any intermediate or finished product. The (+) prefix tells us it's one specific enantiomer, and that chiral purity didn’t just happen by accident—it’s built into our process from the start, for manufacturers who know the difference.

    The Technical Edge: Specifications and Why They Matter

    From a manufacturer’s bench, consistency underpins everything. We've observed that many performance polymers, adhesives, and hardeners call for the trans isomer for a reason—it provides greater rigidity and alters solubility compared to the cis version. Our in-house analytical teams carefully monitor isomer ratios, residual solvents, and ash content every shift. Lower impurities mean fewer surprises mid-process and help avoid sticky situations like foam formation, haze in coatings, or trouble during polymerization.

    Most of the demand for (+)-trans-1,2-cyclohexanedicarboxylic anhydride lands in specialty resins, curing agents for epoxy systems, and as an intermediate for fine chemicals. A lot of chemists ask about particle size, melting range, or compatibility with other common reactants. We don’t just rely on published values; we back everything up with batch-level chromatograms and reproducibility tests. It’s a standard practice here—every drum and hopper gets checked, no matter the batch size.

    Our version consistently runs at a melting point above 200°C, and you can observe the slightly greater rigidity in finished resins when compared with acids or anhydrides made from linear chains. Having a cyclic backbone gives better chemical and heat resistance, and polymers formed from this anhydride keep their integrity rather than brittling or yellowing over time.

    Direct Use Cases: Industry Applications Drawn From Experience

    Over years in production, we’ve handed off material to a range of users—from composite fabricators to OEMs focused on high-performance coatings. The primary demand centers on epoxy formulations and reactive intermediate syntheses, where end-users look for very specific curing speeds or physical properties. In many curing agent blends, our (+)-trans anhydride delivers a sharper gel-time profile and ultimately a stronger finished matrix, critical in automotive, wind energy, and electronics sectors.

    The cycloaliphatic structure of this molecule means you won’t see the yellowing typical in aromatic-based hardeners. For fabricators aiming for colorless or lightly tinted final products, that makes a difference. While polyester and vinyl ester resin manufacturers use a wide range of acid anhydrides, the trans isomer remains favored in electronics encapsulants since it resists degradation under heat and UV.

    Manufacturing facilities producing advanced coatings and sealants notice fewer pinholes and better finish when blending with our material, compared to linear phthalic-based anhydrides or the cis analog. There’s less off-gassing and lower risk of blushing or blooming on the surface, especially if end-users operate in humid, open-air environments.

    Comparing With Other Anhydrides: Lessons From the Plant Floor

    Work with anhydrides long enough, and a few differences become clear that won’t show up on a data sheet or material safety summary. Take phthalic anhydride—while abundant and low-cost, it brings a set of disadvantages to markets where color stability and resistance to hydrolysis are targets. You get a porous, often yellowing material, with potential regulatory concerns over aromatic content.

    Hexahydrophthalic anhydride is another peer, and though structurally related, its mixture of cis/trans isomers alters reactivity and finished product properties. The cis form contributes flexibility but can soften end-use thermosets, so our focus on producing the pure trans isomer is about delivering higher stiffness or thermal resistance, responding to specific technical requirements set by aerospace, microelectronics, or precision molding clients.

    Some companies rely on simple dicarboxylic acids like adipic acid for polymer chains, but their lack of cyclic structure means lower glass transition temperatures and higher permeability to moisture in finished goods. Feedback from customers shows better retention of dielectric properties and dimensional stability with the cyclohexane-based anhydride over linear alternatives.

    Aromatic anhydrides—trimellitic and related compounds—often push epoxies towards brittleness and darken more under high temperatures. With our trans isomer, technicians and product engineers have repeatedly reported a jump in toughness and longevity, especially after hundreds of heating or cooling cycles.

    Why Stereochemistry and Purity Directly Impact Product Performance

    During production, nothing matches early detection of isomer contamination. Without close stereochemical control, you risk batch variability that downstream users can detect in mechanical strength, gloss, or cure profile shifts. We’ve invested in additional chiral column chromatography and worked with partners to validate that our material achieves the minimum required optical rotation values every time.

    Testing finished epoxies—those based on our (+)-trans-1,2-cyclohexanedicarboxylic anhydride—shows consistent performance. At end-user sites, even small shifts in trans/cis ratio change how plasticizers interact and can wreck a recipe. Technicians processing coatings at scale see less need for over-formulation or use of toughening additives. Plastics produced with off-ratio anhydrides usually don’t pass impact or flexural strength testing as easily, which can scrap a week’s worth of runs.

    Because of its high purity, engineers working with our anhydride report reliable, repeatable results across months of production. Production managers at molding sites see throughput gains because cycle times are more predictable, and scrap rates drop due to stable curing. No one calls asking about haze or soft spots once they switch to batches pegged to the pure trans isomer.

    The Supply and Scale Equation: Practice Behind Consistency

    Steady supply only comes with established process reliability. We maintain inventory at multiple tank farms, and run high-volume reactors with in-line sensors to cut down batch variations. Newer teams sometimes ask why we track so many parameters beyond the main assay; but after decades of seeing how minor details snowball—trace moisture, unreacted acid, or shifts in optical rotation—it’s obvious that chemical manufacturing operates on much finer tolerances than datasheets suggest.

    Long-term customers appreciate that a dependable source of (+)-trans-1,2-cyclohexanedicarboxylic anhydride stabilizes their downstream supply chain, keeping quality up while controlling cost overruns from rework or missed deadlines. Losing consistency can disrupt R&D, pilot lines, and full-scale manufacturing alike. No one has time for costly troubleshooting.

    Some users have tried alternative suppliers and discovered that spotty bulk quality triggers slowdowns in everything from batch pre-qualification to automated packaging lines. By emphasizing quality control and transparency about each lot, we've helped clients avoid bottlenecks and unplanned downtime.

    Supporting Sustainability: Materials Choices and Environmental Standards

    The focus on sustainable chemistry has brought new scrutiny to every material used in long-life products or high-volume manufacturing. Our (+)-trans-1,2-cyclohexanedicarboxylic anhydride benefits from a synthesis route that minimizes waste and reduces emissions compared with aromatic-based routes. Reactor designs and solvent recovery systems pull down both VOC emissions and energy use per ton produced.

    Many customers, especially multinationals and OEMs bound by strict carbon targets, push for lower-impact raw materials. Our approach centers on local sourcing of starting materials and precise process control, which cuts down transport emissions and packaging waste. Our waste streams stay separated for recovery, with minimal byproduct generation.

    Landfill avoidance and streamlined secondary treatment of mother liquors help keep regulatory compliance smooth and avoid costly audits or remediation. Final users find value in knowing that their core inputs contribute less to lifecycle energy and pollution scores, which aligns with rising expectations from end-users and regulators.

    Solving Problems: Feedback Loops From Application to Manufacturing

    The best insight into sourcing or switching to (+)-trans-1,2-cyclohexanedicarboxylic anhydride springs from seeing how it performs outside the plant. Over the years, users have flagged unexpected gel times or discoloration caused by marginal inputs from other suppliers. The open flow of feedback between our R&D and industrial customers has shaped process refinements—tighter control of moisture, smaller particle cutoffs, and shifting to bulk packaging for critical uses.

    Some formulating chemists struggle with anhydrides that attract water from ambient air, leading to partial hydrolysis before compounds even reach the mixer. Our packaging solutions, tested over thousands of units shipped, shield each shipment, reducing rework. We also perform temperature-cycling stress tests on sample lots before signing off new production equipment, mirroring the climate exposure our drums might face during transport and storage.

    Whenever a customer’s downstream team spots an issue (maybe a haze after UV exposure or a shift in resin cure), our technical support coordinates with lab and plant teams to isolate the cause, and implements process changes if necessary. We’re as invested in product success as the companies using our product.

    Understanding Trade-Offs: Selecting the Right Anhydride

    It takes more than price to choose the right chemical building block for exacting applications. Some users focus on low cost of phthalic and maleic anhydrides, yet eventual costs surface in the form of shifts in curing speed, reduced resistance to heat or solvents, or regulatory headaches tied to aromatic content.

    Our cyclohexane-based anhydride fits where higher-performing end products—such as corrosion-resistant coatings, electrical encapsulants, or durable fiber composites—demand specific traits. Stereochemistry, purity, and the physical form of the input all translate directly into measurable differences—tensile strength, shelf life, ability to withstand environmental degradation.

    Companies investing in a new product or reformulating existing lines turn to our technical team for runs on pilot lines, comparing their end properties directly. We supply application data, not just analytical results, so that users understand how our (+)-trans isomer stacks up against competitive choices. In some test cases, adopting our material enabled clients to eliminate extra process steps, consolidate resin components, and meet stricter environmental thresholds.

    Regulatory and Compliance Realities

    From a compliance point of view, sourcing and using anhydrides often means navigating a patchwork of safety, handling, and environmental regulations. Our customers expect not just a compliant product, but transparent traceability down to batch production and raw materials origin. Meeting the latest environmental and occupational guidelines depends on tight process oversight—catching trace impurities before they leave the gate, and enabling easier audit trails.

    Our internal compliance systems are built to align with end markets—be they in advanced electronics, automotive assembly, or capital goods production—where material declarations and change management protocols need to be rock solid. We provide documentation, all supported by in-house and independent laboratory confirmation, so procurement and quality managers can build supplier evidence files without delays or guesswork.

    Since anhydrides play an active role in chemical reactions and finished products, end-users (especially in regulated industries) require data on potential extractables, leachables, or unintended byproducts. We collaborate with partners to run in-use studies and provide accurate projections of service life and exposure outcomes under a range of environmental scenarios.

    Investing in Process Improvements for Reliable Supply

    Maintaining a supply of high-purity (+)-trans-1,2-cyclohexanedicarboxylic anhydride means constant reinvestment in both old and new technology. We overhaul reactors, install new air management systems, and keep analytics equipment calibrated to meet evolving product quality targets. Plant operators and lab staff work together, sharing data on batch anomalies or near-misses so we can root out issues quickly and deliver a stable product.

    Automated sampling systems run around the clock, flagging anomalies, while human experience catches shifts that machines struggle with—like subtle changes in odor or flow that precede visible contamination. Operators with years on the line know that catching a problem early means everything, since even the smallest off-quality lot can impact months of downstream production for a global firm.

    Continuous training and skill development take priority, because personnel expertise often bridges the gap between high-level process theory and the realities of plant operation. Many of the process improvements we've adopted came straight from staff working hands-on with equipment. Investing in workers—both in the lab and on the line—results in a product that meets tight specification and has earned trust in demanding applications.

    Collaboration With End-Users Shapes the Future

    We see ourselves not simply as suppliers, but as partners in innovation and manufacturing resilience. Conversations with engineers and developers at customer sites drive many process refinements here. When end-users raise blendability issues, thermal decomposition points, or storage stability, we explore answers with real-world testing, not just in silico modeling.

    We’ve built long-term R&D agreements with some of the top material developers in the world, running joint pilot programs to explore next-generation polymers, electronics encapsulants, and specialty adhesives. Through these programs, we challenge our own assumptions and come away with new knowledge—translating client feedback into targeted process control changes.

    Working with demanding customers in aerospace, electronics, or medical device spaces, we’ve fine-tuned chiral purity controls and developed specialized packaging and shipping solutions that extend shelf life and reduce risk of contamination. In each case, decisions made on the floor here contribute to stronger, safer, and more advanced end products.

    Looking Ahead: Anticipating Industry Needs

    Change moves fast in industrial chemistry. New applications for (+)-trans-1,2-cyclohexanedicarboxylic anhydride open up as markets chase lighter, stronger, and longer-lasting materials. Our team tracks evolving performance standards, compliance rules, and sustainability goals—factoring those into the adjustments we make in process and supply.

    We anticipate expanded use in EV components, advanced wind turbine blades, and energy-efficient infrastructure coatings, as end-users raise the bar for durability and climate resilience. Our multi-site investments in process automation, emissions capture, and traceability lay the groundwork for an even more consistent and future-proof supply.

    Having seen firsthand how a poorly controlled chemical chain reaction can grind whole projects to a costly stop, we’re committed to the cycle of constant improvement—technical excellence, plainspoken support, and grounded insight. In the end, those details build tangible value for every manufacturer, formulator, and innovator who depends on their inputs staying reliable, batch after batch.