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Thymol Iodide

    • Product Name Thymol Iodide
    • Alias Iodothymol
    • Einecs 232-133-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    191731

    Chemical Name Thymol Iodide
    Chemical Formula C10H13I2NO
    Cas Number 552-22-7
    Molecular Weight 432.03 g/mol
    Appearance Yellowish-brown powder
    Melting Point 157-159°C
    Solubility In Water Insoluble
    Storage Temperature Room temperature
    Odor Odorless
    Uses Antiseptic, topical disinfectant
    Stability Stable under recommended conditions
    Boiling Point Decomposes
    Synonyms Aristol, Iodothymol

    As an accredited Thymol Iodide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle with a tightly sealed cap, labeled "Thymol Iodide, 25g," hazard symbols, batch number, and manufacturer details.
    Shipping Thymol Iodide should be shipped in tightly sealed containers, protected from light and moisture. Handle with care, avoiding exposure to heat or incompatible substances. Clearly label the package as a chemical substance. Comply with local, national, and international regulations for transport, including appropriate documentation and safety data sheets.
    Storage Thymol Iodide should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from sources of heat, ignition, and incompatible substances such as strong oxidizers and acids. Protect it from moisture and direct sunlight. Ensure containers are clearly labeled and handle in accordance with standard chemical safety protocols to prevent contamination or degradation.
    Application of Thymol Iodide

    Applications of Thymol Iodide in Industrial Manufacturing

    Thymol iodide sees specialized use in several regulated sectors, primarily due to its antimicrobial and deodorizing properties. As a direct manufacturer, we supply this material for niche applications that demand precise purity, safety, and performance in compliance with strict industrial standards.

    1. Topical Antiseptic Powders and Ointments Formulation

    Pharmaceutical and veterinary producers incorporate this compound in medicated powders and ointments designed for topical disinfection and wound management. Its inclusion helps control microbial growth on skin lesions, post-operative incisions, and superficial wounds. Formulators carefully balance it with absorptive excipients and mild astringents to maximize antimicrobial coverage without causing tissue irritation. Proper ingredient sourcing and batch traceability ensure conformance with monograph requirements. Final dosage forms undergo microbial limit testing, stability studies, and allergen assessments before release for clinical or animal use.

    Industry compliance standards

    • USP/NF Monograph for Thymol Iodide (where applicable)
    • Ph. Eur. Reference Standards
    • U.S. FDA 21 CFR 330 (Topical Antiseptic Drug Products)
    • Current Good Manufacturing Practices (cGMP)
    • Veterinary Medicines Directorate (VMD) guidelines for animal use

    Typical usage ratio

    • 0.5% to 3.0% by weight in powder blends, up to 2.0% in ointment bases
    • Adjusted based on required antimicrobial activity, substrate compatibility, and local regulatory limits

    Downstream process integration

    • Blended into dry formulations during powder mixing or pre-milled with filler agents
    • Incorporated post-emulsification for semi-solid ointments, under laminar environmental controls
    • Subjected to final filtration and packaging in sterile containers

    Final product types

    • Medicated surgical wound powders for hospitals and clinics
    • Veterinary antiseptic ointments and dusting powders
    • Over-the-counter topical disinfectant powders for human use

    2. Oral Hygiene Powder and Paste Manufacturing

    Dental and oral care companies employ this ingredient in the formulation of specialty tooth powders, gum treatment blends, and therapeutic dentifrices. Its activity against oral bacteria contributes to odor control and adjunctive treatment of minor oral lesions. Manufacturers standardize the raw material for heavy metal content and organoleptic profile. Regulatory requirements dictate the careful control of use levels, ensuring no adverse effects on oral mucosa or teeth surfaces. Finished goods undergo stringent release testing for microbiological safety, stability under varied humidity, and uniformity of active ingredient distribution.

    Industry compliance standards

    • FDA 21 CFR 355 (Oral Health Care Drug Products)
    • European Cosmetics Regulation (EC) No 1223/2009
    • ISO 16408:2015 (Dentifrices—Requirements and test methods)
    • Health Canada Cosmetics Ingredient Hotlist

    Typical usage ratio

    • 0.1% to 0.8% by total product weight for oral hygiene application
    • Dose adjusted depending on target product (powders vs. pastes) and local country limits

    Downstream process integration

    • Added during dry blending stage for tooth powders
    • Suspended in liquid base after main emulsification and prior to viscosity adjustment in pastes
    • Subjected to in-process sampling for uniform mixing and microbial checks

    Final product types

    • Therapeutic tooth powders for decay-prone users
    • Gum treatment oral care blends
    • Specialty dentifrice formulations sold in pharmacies and dental clinics

    3. Deodorizing Additives for Medical and Industrial Dressings

    Producers of wound care dressings and industrial absorbent pads utilize this compound as a deodorizing additive, controlling malodor associated with exudate or biological waste. Its low vapor pressure and mild antiseptic nature make it suitable for constant-contact applications. Compositional design often combines absorbent cellulose with the additive, ensuring sustained release of the active during use. Formulation engineers validate compatibility with hydrocolloid surfaces, foams, and antibacterial coatings. Regulatory review includes safety data for chronic exposure and compatibility testing with skin adhesives.

    Industry compliance standards

    • EN 13726 (Test methods for primary wound dressings)
    • ISO 10993 series (Biological evaluation of medical devices)
    • CE Marking under EU Medical Device Regulation (MDR 2017/745)
    • FDA 510(k) premarket notification for medical dressings

    Typical usage ratio

    • 0.2% to 1.0% by weight in absorbent dressing matrices
    • Tuning based on required deodorization efficacy and acceptable exposure levels

    Downstream process integration

    • Dispersed in slurry during fabrication of non-woven layers
    • Applied as a fine powder at lamination stages
    • Integrated into hydrocolloid sheets during calendaring

    Final product types

    • Surgical wound dressings with odor control
    • Absorptive pads for ostomy management
    • Industrial absorbent pads for laboratory and clinical waste

    4. Additive for Veterinary Hygiene and Disinfection Products

    Animal health and livestock management manufacturers incorporate this raw material into hoof powders, stable disinfectants, and bedding treatments for odor control and microbial suppression. Blends are evaluated for efficacy against Gram-positive and Gram-negative organisms found in livestock environments. Formulation varies based on animal type, application frequency, and bedding material compatibility. Safety studies confirm no undesirable residue in food-producing animals. All production lots are traceable to support quality assurance audits and veterinary regulatory reviews.

    Industry compliance standards

    • OIE Terrestrial Animal Health Code (disinfectant recommendations)
    • European Union Biocidal Products Regulation (BPR, Regulation (EU) 528/2012)
    • ISO 9001:2015 (Quality management for animal health products)
    • Relevant local veterinary regulatory approvals

    Typical usage ratio

    • 0.3% to 1.5% by weight in hoof and bedding powders
    • Adjusted based on required frequency of application and environmental load

    Downstream process integration

    • Added during final blending phase for veterinary powders
    • Post-milled into bulk bedding or carrier granules
    • Packaged under controlled conditions to maintain particle integrity

    Final product types

    • Hoof care and wound powders for farm animals
    • Stable bedding additives for large-scale livestock operations
    • Veterinary disinfection powders for rural and peri-urban animal facilities

    5. Odor-Control Components for Specialty Rubber and Compound Plastics

    Manufacturers of compound rubbers and specialty plastics occasionally use this chemical to impart mild antimicrobial and odor-suppressing properties to flexible products used in sensitive environments. This additive supports hygiene in items such as medical gloves, healthcare flooring, and laboratory work surfaces. Processing parameters, including temperature and mixing duration, are optimized to prevent loss of active due to volatilization. Batch records include both active content verification and finished article testing according to functional and migration standards.

    Industry compliance standards

    • REACH Annex XVII and CLP Regulation for chemical safety in polymers
    • ISO 10993-10 (Irritation and skin sensitization in medical devices)
    • EN 14041 (Floor coverings—Essential characteristics)
    • US FDA 21 CFR 177 for indirect food-contact plastics (if applicable)

    Typical usage ratio

    • 0.05% to 0.4% by weight in polymer compound formulations
    • Adjusted according to end-use requirements and process temperature sensitivity

    Downstream process integration

    • Pre-blended with plasticizers, stabilizers, and bulking agents before extrusion or molding
    • Introduced after pre-heating step to minimize volatilization
    • Quality checked for uniform dispersion and retained activity in finished product

    Final product types

    • Antimicrobial medical gloves
    • Odor-inhibiting hospital flooring and wall panels
    • Protective laboratory mats and work surface covers
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    Certification & Compliance
    More Introduction

    Thymol Iodide: Practical Perspectives from Our Production Line

    Grounded in Experience: Our Approach to Thymol Iodide

    Manufacturing chemicals is not about ticking boxes on datasheets. Each batch draws on years in the plant, deep dives into raw materials, and hard lessons from customers’ feedback. With thymol iodide, we have seen demand grow from both compounding pharmacies and technical industries. In our daily work, the practical value of thymol iodide has never been about trending uses or buzzwords. It matters because it answers very particular needs, often overlooked by more conventional substitutes. Our team witnesses this every step of the way, from quality checks at our incoming iodine and thymol drums, right down to the scent of the final drying room.

    Thymol Iodide Model and Specifications: What Sets Our Material Apart

    We produce thymol iodide under the model designation TYI-98, which reflects our standard minimum assay of 98 percent. Each lot is validated by direct iodometric titration and HPLC trace analysis. Moisture content rarely rises above 0.4 percent at dispatch—an important threshold for storage reliability. Particle size matters, especially for topical blends, and our standard cut ranges from 100 to 200 mesh, with customized fractions for specific blend requests. Appearance is a fine, light yellow-brown powder, with a characteristic herbal-iodine odor, signaling proper manufacturing controls and the stability of the compound.

    Packing is not an afterthought. We use multi-layer liner bags inside rigid drums, 25kg net, and smaller packs for labs, because moisture and contamination remain the main risks to thymol iodide quality. Stability studies conducted in our own environment show that this packaging best preserves the chemical’s integrity, even in more humid conditions.

    Why Thymol Iodide Still Matters: Genuine, Problem-Solving Usage

    Thymol iodide answers calls from both laboratories and field applications where neither pure thymol nor simple iodine will work. Most users first meet it in formulations that demand sustained antimicrobial performance—either as dusting powders in wound care or as stabilizers in veterinary preps. Hospitals trust thymol iodide because it combines the mild antiseptic properties of thymol with the broad, penetrating efficacy of iodine, packaged in a much less irritating, less volatile form.

    Many customers ask why not just use standard iodine. In practice, elemental iodine can easily irritate tissue, evaporate, and stain equipment or skin. Thymol itself lacks the broad spectrum synergy provided by iodine. By making an iodinated derivative of thymol, the reactivity softens, volatility drops, and stability increases, allowing precise dosing in pharmaceutical and technical blends. Anyone who has seen complaints from veterinarians about staining or skin irritation knows why thymol iodide earns its place.

    Dentistry also finds steady value here, both in mouthwashes and as a slow-release bacteriostatic in some fillings. Our interaction with dental universities revealed a strong preference for thymol iodide when needing to manage deep-seated infections without overwhelming mucosal tissues. In powders for wounds and ulcers, thymol iodide brings both hygroscopic stability and a mild, persistent aroma that reassures both patients and caregivers.

    Comparison with Other Antiseptics: A Chemist’s Perspective

    Our plant team often fields questions about why thymol iodide costs more than simple iodine tinctures or straight thymol. Years of production have taught us that the extra synthesis step isn’t just about chemical composition—it’s about how the product interacts in the real world. Pure iodine volatilizes unless sealed tightly, and its activity as an oxidant can lead to unpredictable results in mixed preparations. Thymol alone cannot deliver the sustained bactericidal punch or the synergy needed for some clinical uses.

    We’ve put thymol iodide side by side with povidone-iodine, chlorhexidine, and older phenolic antiseptics. While povidone-iodine is still king for surgical scrub, its water solubility and fast release sometimes backfire in wound healing: tissue irritation and a short contact window. Thymol iodide, by contrast, shows a gentler profile—more persistent, less aggressive on granulating tissue, less likely to run into stability issues in powder formulations. Our customers in rural clinics and field hospitals report fewer logistic headaches with thymol iodide powders than with some liquid alternatives that need careful closure and refrigeration.

    Even in technical usage, the material demonstrates unique value. Our industrial clients blend thymol iodide into compounds where resistance to oxidation and shelf stability make or break a batch. In such cases, the cost is justified by the reduction in product rework and less frequent complaints about active content loss. Many technical chemists recognize the compound’s blend of organoleptic and antimicrobial properties, suiting it for sensitive products meant for close contact with skin, food, or animal habitats.

    Production Realities: Consistency, Safety, and Traceability

    Making thymol iodide safely in batches that meet demanding specifications isn’t something an improvised plant can guarantee. Our process runs in closed, jacketed vessels under controlled exothermic conditions. The generation and removal of hydrogen iodide gas is a step requiring strict attention to local exhaust and monitoring—much more involved than with standard halogenations. All operators wear full PPE, not just for their own safety but for consistent product quality. Improperly handled, the by-products can taint the final material or create impurities, which we check by TLC and GC–MS screening on every run.

    Traceability runs throughout our log system, recorded lot by lot, from the moment thymol and iodine enter the store room. This culture of documentation is not just about meeting regulatory requirements. Recalling one particularly tricky year with a global shortage of pharmaceutical-grade iodine, tight lot control allowed us to adjust procurement in time, sidestepping supply interruptions. We also found during client audits that offering full process transparency wins trust—no one wants to guess what’s really ending up in their compound pharmaceuticals.

    Waste minimization is another concrete achievement. Proper condensation and neutralization systems cut down on iodine vapor release and reduce the burden on our local environment. The main point is safe, efficient operation from raw material handling to barrel sealing, something only possible with long experience, well-trained hands, and rigorous in-house procedures.

    Where Usage Is Changing: Insights from Our Customers

    Demand for thymol iodide continues to shift with changes in regulatory priorities and end-user awareness. We notice tighter scrutiny on preservatives in animal feed and skin-contact materials, opening new space for thymol iodide’s low-toxicity, broad-range properties. As traditional antibiotics face tighter controls, the broader-spectrum but milder compounds like thymol iodide find renewed applications, especially in markets with less stringent cold-chain infrastructure.

    Our pharmaceutical clients shift focus to products with a documented lower rate of allergic reactions and more predictable thresholds for tissue recovery. Through direct engagement and technical troubleshooting, we have helped veterinarians move from older, harsher iodine powders to thymol iodide blends with fewer complaints of irritation and better shelf-life in tropical climates. Some agricultural clients experiment with thymol iodide in seed coatings and disinfectants, seeking the balance between stability and safety for both users and plants.

    A striking example comes from our partners in wound care powder manufacturing, who tell us that patient feedback on odor and application experience influences product loyalty as much as clinical results. Thymol iodide’s slightly herbal scent, without heavy volatility, makes it a preferred choice over more pungent or persistent-smelling alternatives. A wound powder that stings less and smells mild finds more repeat use in both professional and home care settings.

    Regulatory attention is shifting, too. Thymol iodide’s established monographs in several pharmacopeias have made cross-border documentation easier, reducing headaches for both us and our clients as more countries standardize active ingredient lists for antimicrobials and wound care.

    Potential Solutions for Common Production and Usage Challenges

    One common problem our partners face is powder caking during long-term storage. Through iterative improvement in our production line, we minimized moisture ingress by switching to more effective drying cycles and adding in-line checks for water content. Packaging upgrades followed—stiffer drum linings and extra desiccant packets reduced post-shipment clumping incidents by almost a quarter in the past two years.

    Customer labs occasionally encounter blending difficulties when incorporating thymol iodide into fine ointments. Listening to their technical staff, we developed an optional micro-milled grade, widening our size specification range. Lowering particle size without increasing impurity risk required multiple trials with equipment upgrades, but the net result: smoother dissolution and less grittiness in topical applications. User feedback in post-market surveys improved, closing the loop from our process development to end-user satisfaction.

    We run ongoing comparisons between our in-house and external batches using blinded testing, measuring effects on stability and antimicrobial activity. This not only guides our raw material selection but also keeps us responsive to minor performance differences between growing seasons or iodine suppliers. Occasionally, tighter than anticipated regulations on iodine content push us to adjust protocols. Established relationships with regulatory teams and absorption of extra compliance testing into our normal workflow help us avoid last-minute product holds or delays.

    Environmental and occupational safety demand constant vigilance. Regular investment in scrubbing and containment upgrades, and extending shift training for operators and maintenance staff, make a practical difference at the factory floor level. These steps don’t just tick boxes—they directly reduce downtime, rework, and loss, letting us maintain delivery standing and confidence for repeat clients.

    The Human Factor: Stories from Behind the Batches

    Veteran operators remind new hires that success with thymol iodide production comes from more than following a checklist. After two decades handling both small pilot and full-batch loads, we’ve seen how the details—raw material selection, drying conditions, packaging—shape final outcomes for healthcare workers and their patients. More than once, clean shipping, correct labeling, and technical follow-up turned a near-missed specification into a loyal, long-term customer.

    Our technical support team fields hundreds of queries yearly, from stability concerns in tropical storerooms to rare requests for atypical mesh cuts for research blends. The conversations often reveal gaps between textbook chemistry and real-world constraints—like shelf-life pressure, delivery latency, or subtle differences in antimicrobial properties under varied conditions. We adapt and learn, feeding back both problems and creative solutions into our process improvement cycles.

    Every batch shipped isn’t just a transaction, but a chain of trust. Evidence-based claims, reliable service, and open communication mean more to end users than mere specifications. Our track record with thymol iodide stands on a foundation of technical openness and long-term supplier relationships, built through patient listening and careful execution.

    Looking Forward: Continual Improvement and Responsible Production

    We remain committed to active learning from our customers, regulatory changes, and evolving technical challenges in thymol iodide use. Responsible procurement, rigorous batch testing, and open communication with users remain our main tools for producing a product that’s both predictable and valued. As expectations for safety and stability increase, our experience suggests that continual small improvements—faster drying, better lot documentation, quicker technical support—make the difference between commodity and partner.

    New uses—ranging from biopreservatives to advanced veterinary formulations—continue to push us to optimize both process and communication. We see regular audits and transparent reporting not as hurdles, but as an opportunity to demonstrate the robustness of our system and the reliability of our product. With each round of feedback, we strengthen both our product and the relationships that sustain it.

    Thymol iodide has never been a cure-all or a mainstay of the chemical world, but in its niches, it solves real problems for people who rely on steady, predictable results. After years in the trenches of manufacturing, the lessons are clear: attention to detail—at every step from raw input to end customer—yields a product that meets not only abstract specifications but practical, human needs.