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Thiophanat-Ethyl

    • Product Name Thiophanat-Ethyl
    • Alias Topsin-M
    • Einecs 245-877-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    505576

    Chemical Name Thiophanat-Ethyl
    Common Use Fungicide
    Molecular Formula C12H14N4O4S2
    Cas Number 23564-05-8
    Appearance White to off-white crystalline solid
    Mode Of Action Systemic, inhibits fungal mitosis
    Solubility In Water Low
    Toxicity To Humans Low
    Formulation Types WP (wettable powder), SC (suspension concentrate)
    Target Pathogens Ascomycetes, Basidiomycetes, Deuteromycetes
    Application Crops Cereals, fruits, vegetables, ornamentals
    Residual Activity Medium
    Storage Condition Cool, dry place
    Trade Names Topsin-M, Cercobin, Tuzet
    Decomposition Temperature Above 200°C

    As an accredited Thiophanat-Ethyl factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging for Thiophanat-Ethyl features a white plastic bottle labeled "Thiophanat-Ethyl 500g" with safety symbols and usage instructions.
    Shipping Thiophanat-Ethyl should be shipped in tightly sealed, clearly labeled containers, protected from moisture and direct sunlight. It must be handled as hazardous cargo, with compliance to local, national, and international transport regulations. Avoid rough handling and store away from incompatible substances. Use appropriate safety data sheets during shipping.
    Storage Thiophanat-Ethyl should be stored in a cool, dry, well-ventilated area, away from direct sunlight and sources of ignition. Keep it in tightly closed, original containers, away from food, animal feed, and incompatible substances such as strong oxidizers. Ensure the storage area is secure and clearly labeled, with access limited to trained personnel. Avoid exposure to moisture and extreme temperatures.
    Application of Thiophanat-Ethyl

    Applications of Thiophanate-Ethyl in Industrial Manufacturing

    Thiophanate-Ethyl, as an industry-grade systemic fungicide, serves multiple specialized roles within the agricultural supply chain and other select sectors. Our manufacturing expertise ensures production batches with consistent technical specification, purity, and performance metrics matched to the requirements of professional downstream applications. Explore targeted industrial scenarios where our material delivers measurable processing and functional value.

    1. Formulated Agricultural Fungicides

    The majority of Thiophanate-Ethyl manufacturing volume integrates into crop protection products for the control of a wide spectrum of fungal pathogens in food and cash crops. Major agrochemical formulators utilize it as an active ingredient within wettable powders, water dispersible granules, and suspension concentrates. Precision blending within pesticide formulation plants ensures reliable dispersion and bioavailability tailored to major crop types, while closely tracked batch QC underpins regulatory compliance and end-use safety. Manufacturers calibrate input ratios to achieve specified loading for local farm use patterns and resistance management plans.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products (FAO/WHO)
    • European Union Regulation (EC) No 1107/2009 for plant protection products
    • GB 2763-2021 (China MRLs for Pesticides in Foods)
    • US EPA Pesticide Registration and Tolerance Regulations (FIFRA)

    Typical usage ratio

    • Active loadings of 70-80% in technical concentrate manufacture
    • 10-50% in ready-to-use agricultural formulations, varied for designed field strength and application mode
    • Adjustments based on crop target spectrum or composition of synergistic actives

    Downstream process integration

    • Pre-mixing with inerts, surfactants, dispersants, and stabilizers in batching tanks
    • Wet-milling or granulation to achieve particle size distribution for user safety and application uniformity
    • Final QA sampling for content uniformity and shelf-life stability before packaging

    Final product types

    • Wettable powder fungicides for cereals, bananas, tomatoes, and peanuts
    • Suspension concentrates for orchard and greenhouse crops
    • Seed treatment formulations for cereals and horticultural seeds
    • Multi-active blend fungicides for resistant pathogen management in specialty crops

    2. Turf and Ornamental Plant Disease Control

    Professional landscape and turf management companies incorporate Thiophanate-Ethyl in protective maintenance programs for golf courses, sports fields, nurseries, and urban green spaces. Product manufacturers formulate disease management products with specific granularity, solubility, and residual persistence matched to the ornamental and amenity sector. Each production run undergoes QA according to the green industry’s particular application equipment and environmental safety profiles, emphasizing root-zone safety and residue controls.

    Industry compliance standards

    • US EPA Pesticide Product Labeling for Turf and Ornamentals
    • California DPR Regulations for Professional Landscape Chemicals
    • EU Regulation (EC) No 1107/2009 – Non-food applications
    • ASTM E2847 Standard Guide for Turf Management Chemicals

    Typical usage ratio

    • Formulations typically contain 20-30% active ingredient in granular products
    • Liquid concentrates designed at 10-20% w/w for easy dilution and calibrated application
    • Adjustment depends on geography, target fungal species, and turf variety

    Downstream process integration

    • Micro-granulation and dust control treatments for uniform application on bulk carriers (granular types)
    • Mixing with carrier liquids and wetting agents for concentrate bottling lines
    • Post-production residue and particle size QA for landscape end-use compatibility

    Final product types

    • Granular turf fungicides for preventive broad-acre applications
    • Emulsifiable concentrates for landscape service contractors
    • Foliar sprays and dips for commercial nursery stock protection
    • Protective soil drench products for tree and shrub maintenance

    3. Post-Harvest Crop Protection

    Post-harvest produce handling and packhouse operations depend on highly specific fungicide formulations to maintain shelf life and prevent storage losses from fungal diseases. Our technical Thiophanate-Ethyl serves as a core input for post-harvest fungicide dips, sprays, and coating solutions, which are subject to stringent food safety regulations and residue requirements. Post-harvest chemical processors must precisely calibrate dosing for fruit and vegetable type, local maximum residue limits, and environmental controls specific to food export markets.

    Industry compliance standards

    • Codex Alimentarius Commission MRLs
    • US FDA Food Safety Modernization Act (FSMA) for imported produce
    • EU Regulation (EC) No 396/2005 for produce MRLs
    • Chinese GB 4819 standards for post-harvest food chemicals

    Typical usage ratio

    • Formulations designed at 2-5% active ingredient in concentrate solutions
    • Working solutions prepared at 0.05-0.2% w/v for coating or immersion treatments
    • Adjusted for produce sensitivity and customer export destination

    Downstream process integration

    • Blending with food-grade adjuvants, wetting agents, and thickeners in controlled mixing tanks
    • Batch-specific QA of active content and food-contact compatibility
    • Packing into closed system dispensers for packhouse or processing line integration

    Final product types

    • Fruit and vegetable post-harvest fungicidal dips for citrus, stone fruit, table grapes, and melons
    • Protective coatings for cold storage apples and pears
    • Sanitizing sprays for root vegetables prior to export packaging

    4. Seed Treatment Agents

    Seed technology firms and seed processors apply Thiophanate-Ethyl to manage seed- and soil-borne fungal diseases, thereby increasing germination rates and crop starts. Material enters proprietary formulation lines to produce coatings that adhere and remain active during storage and sowing. Production requires careful rheology management and particle size monitoring, as uniform distribution is critical for downstream mechanized sowing and high-value hybrid varieties. Formulated products must satisfy regional seed treatment and labeling guidelines for export and domestic sales.

    Industry compliance standards

    • OECD Guidelines for the Testing of Chemicals—Seed Treatment Products
    • US EPA & Federal Seed Act requirements for treated seeds
    • EU Regulation (EC) No 1107/2009 for treated seed certification
    • APVMA Regulatory Guidelines for Seed Treatments (Australia)

    Typical usage ratio

    • Input at 10-35% active in commercial seed coat concentrate formulations
    • Final diluted application rate at 0.1-0.5 g a.i./kg seed, per crop and disease target
    • Process lines calibrate addition to match local agronomic recommendations

    Downstream process integration

    • Inline coating or blending with film-formers and colorants for precise dosage application
    • QC sample monitoring for coating thickness and active distribution
    • Pre-packaging in sealed containers ensuring treatment adherence and shelf-life

    Final product types

    • Treated cereal seeds for wheat, barley, and soybeans
    • Vegetable seeds with fungicidal coatings for commercial greenhouses
    • Hybrid maize seed treatments for export compliance
    • Horticultural seed packets for commercial sowing

    5. Industrial Mushroom Cultivation

    Commercial mushroom farms utilize targeted fungicidal treatments to suppress competitor fungi during the spawning, casing, and cropping phases. Mushroom substrate and casing manufacturers blend Thiophanate-Ethyl into sterilized growing media and surface treatments, ensuring mycelium viability and reducing post-harvest losses. Application rates and guidelines align with food-chain safety rules, requiring careful batch record-keeping and residue monitoring throughout logistics and harvest.

    Industry compliance standards

    • European Commission Regulation 1881/2006 for foodborne chemical residues
    • US EPA and local-use restrictions for edible fungi
    • Japanese Food Safety Commission standards for mushroom residue limits
    • GAP Certifiable Production for edible mushrooms

    Typical usage ratio

    • Incorporation at 0.05-0.1% active ingredient in casing layer treatments
    • Fungicide application rates tailored to substrate moisture, variety, and grower SOP
    • Formulation adjustments to meet region-specific cropping cycles

    Downstream process integration

    • Pre-mix with sterile compost or casing media in batch mixers
    • Spray or dip application to compost beds pre-spawn inoculation
    • Regular QA sampling for residue compliance and fungal community impact

    Final product types

    • Edible mushroom substrate additive packs for Agaricus, Pleurotus, and Shiitake cultivation
    • Casing mix treatment products for commercial mushroom farms
    • Packhouse disease control solutions for harvested mushrooms
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    Certification & Compliance
    More Introduction

    Thiophanate-Ethyl: Advancing Crop Protection Through Reliable Chemistry

    The Manufacturer’s Perspective on Real-World Applications

    Working in the field of synthetic fungicides, our days begin in the clatter of reactors and echo with the chatter of ongoing process checks. The commotion seldom slows down, because busy seasons in agriculture do not allow for mistakes or shortfalls. Thiophanate-ethyl remains at the front line of our production floor. Its full name sometimes catches people off guard, but those who deal with blights and mildews recognize the value of this compound the moment they hold the package in their hands. The chemistry brings together the stability of an aromatic system and the practical, multi-site action demanded by modern agronomy.

    Origin, Process, and Purity in Focus

    Our engineers monitor every detail, from the careful weighing of o-phenylenediamine to the final crystallization. Each batch of thiophanate-ethyl undergoes a sequence of filtration, drying, and particle-size adjustment. Minimum impurity levels remain non-negotiable. Getting the material just right takes more than following a flowchart—it means scrutinizing the melting point, running HPLC on every drum, and refusing to release product before specifications clear a demanding threshold. Our technical staff see the wear and tear that lesser quality products cause downstream, with filter clogging, sprayer residue, and unpredictable dissolution rates.

    Why Formulation Matters

    Thiophanate-ethyl usually ships as a fine, powdery solid with a soft, off-white appearance. Particle consistency changes everything for our customers. Fine and even granulation reduces dust during application and ensures that the material disperses cleanly into water. Our line-up includes base technical grade and several ready-to-formulate intermediates. Water-dispersible granules and wettable powders provide the flexibility needed by growers with modern spraying systems. Over the years, significant feedback from orchard managers and greenhouse operators alike has reshaped the physical specifications of our product, including moisture control and anti-caking additives that respond to real-field demands.

    The Science Behind Versatility

    Our teams put a lot of stock in why thiophanate-ethyl remains effective across so many crop types. Once applied, the compound penetrates the plant cuticle, spreading through the internal water-transport system. This upward movement ensures that foliage and even developing fruit receive active protection. Many broad-spectrum fungicides work through single-site action, making crops vulnerable to mutating pathogens. In contrast, thiophanate-ethyl attacks fungal cells at multiple points, interfering with microtubule assembly and the division of genetic material. This reduces the likelihood of resistance, a fact valued by growers faced with rapidly evolving plant diseases.

    Field Experience and Practical Outcomes

    Our history with local extension agents and co-op agronomists has shown us what success in the field looks like. Standard usage covers fruits, vegetables, ornamental plants, and turf. Where powdery mildew, Sclerotinia, or Fusarium root rot set in, a timely application often means the difference between an ample harvest and a struggling one. Many of our customers report visible improvement in plant health within days. Because the residue profile is gentle, pre-harvest intervals can be kept reasonable, giving growers room to plan their activities without being boxed in by chemical constraints.

    In practice, a dose of 0.5 to 1 kilogram per hectare usually strikes the balance for prevention and early intervention. Over-applying wastes both chemistry and money, while skipping doses courts disaster, especially in humid, pathogen-prone areas. Our field reps notice that precision in mixing solutions is the area with the steepest learning curve for new users. So we developed mixing guides and held on-site workshops, ensuring that growers measure accurately rather than estimate.

    Meeting the Challenge of High-Stakes Pathogen Control

    Farmers tell us stories about high humidity summers and how that triggers a scramble to protect tomatoes or soybeans. These field problems brought clarity to our formulation design years ago. Rain-fastness became a top request. The question always came—can the product hold up after intense rain cycles? Our scientists adjusted the surfactant balances and coating agents to improve adhesion and persistence in the canopy. This also reduces the need for back-to-back reapplications, protecting yield and keeping costs in check.

    Comparing Old and New Solutions

    The crop protection landscape constantly evolves. Some older compounds, such as benzimidazole fungicides, still claim a place in integrated management. Our thiophanate-ethyl stands apart because it includes a broader activity spectrum and slower resistance buildup. Users complain that legacy products force tighter spray schedules or require mixing multiple active ingredients to achieve comparable results. In our facility, we often examine returned products—sometimes containing outdated carbamates or copper-based mixtures—and see clear residue, caking, or insufficient dissolution.

    We listened and adjusted. Our product leaves fewer residues, gets in and out of tanks with less operator effort, and rinses clean from hoses and nozzle heads. These details influence long-term maintenance costs, and many farm managers switch to our material to cut down unnecessary downtime during busy spraying windows.

    Worker Safety and User Confidence

    Keeping things safe on the manufacturing line gives us a perspective that we pass on to the end user. The raw form demands proper handling—nitrile gloves, masks, and splash protection. We provide extensive training and literature, based not on generic admonitions but on the incidents, big and small, from years of routine handling. In field practice, we recommend loading the dispenser in outdoor, well-ventilated spaces. We participate in outreach sessions to explain why direct skin contact and inhalation present risks and how to avoid them altogether. These sessions aren’t just lip service. Field audits and third-party sampling make sure our guidelines aren’t just posted—people follow through to protect themselves, their families, and their livestock.

    Sustainability and Environmental Considerations

    We did not always weigh environmental impact as closely as we do today. The change came from stricter audits and the simple reality that rivers and soils do not forget careless chemical use. Thiophanate-ethyl, unlike many older chemistries, breaks down into benign byproducts in soil within a reasonable window. Our laboratory data shows that after 30 to 90 days, active residues drop below measurable limits. We publish these figures and update them as new degradation studies come in. Local regulators sometimes need third-party confirmation, and we open our sites for these audits.

    Our pride goes into the steps we take to reduce dust, recycle wastewater, and reclaim solvents during manufacture. Many customers, especially those exporting to sensitive markets in North America and Europe, ask for environmental performance data before ordering. The first question is about residues in ground water—we are open about our numbers and publish full breakdown details on demand.

    Handling, Storage, and Shelf Life: Lessons Learned Over Time

    Repeated feedback from rural depots and warehouses taught us the lesson that temperature, humidity, and packaging have an outsized effect on product lifespan. Sealed, moisture-proof bags or high-density drums did more than just improve shelf life—they also cut spoilage rates significantly. Several years ago, one of our distributors lost a sizable batch due to improper pallet stacking in a leaky shed, and the loss pushed us to include new desiccant pouches and humidity color indicators in the packaging. Discoloration and clumping point to moisture ingress, and now nearly every large-scale user can inspect the condition before ever unsealing a bag. This practical solution reduced returns but, more importantly, kept product application rates predictable throughout the growing season.

    Which Crops and Pathogens See the Greatest Benefit?

    Some growers look for silver-bullet solutions. Our real-world experience shows that thiophanate-ethyl serves best where disease pressure stays moderate to high. Common targets include:

    Our extension partners see particular results with stone fruits, which seem to show better shoot and flower recovery post-application. Some integrators rotate this compound with contact fungicides, making use of its systemic reach and residual activity. Every season, we receive new requests from specialty berry and grape growers, reflecting the shifting disease profiles that come with changing weather patterns.

    International Standards and Quality Assurance

    Export customers raise pointed questions about active ingredient content and impurity profiles. Our laboratories run batch-by-batch checks for crystalline purity, melting point, and absence of regulated impurities. We maintain a database of certificates dating back over a decade. This archive often resolves compliance questions before the containers have even left the port.

    Our own product exceeds the 95% technical grade standard in nearly every lot; only in rare cases where specified, do we ship anything lower. We track this through HPLC quantification and matching the retention time, not conjecture. Feedback from growers in Southeast Asia, Latin America, and Europe shapes our targets during technical support. We do not leave users hanging with questions about how to clear customs or pass local residue testing; our support staff walk them through document requirements and chain-of-custody records.

    Differences from Other Benzimidazole Fungicides

    Over the years, competitors entered the market with several benzimidazole fungicides, most aiming for the farmgate or cooperative level. We invest in process control and keep our thiophanate-ethyl distinct by three major factors:

    1. Consistency in composition: Some products cut corners on micronization, shifting the bulk density of the powder and creating application headaches. We control not only active ingredient content but also fine-tune the physical matrix—achieving reliable suspensibility and reducing sediment.

    2. Fast, clear solubility: During field audits, old or inadequately milled batches from other sources showed clogs in spray nozzles and absorption on hoses. We use an additional milling stage and anti-static treatment, solving this frustration for both small orchard operations and industrial-scale sprayers.

    3. Targeted residue management: Our batches leave low residue on treated produce and soils, backed by consistent analytical testing. This increases market access in export-focused operations—mango, citrus, table grape, and leafy green packers benefit most.

    From R&D to Daily Use: Keeping Improvements Real

    Our research arm partners with agronomists both in and outside the region to trial each minor process or formulation tweak. Feedback does not stay in internal memos; we drive those changes directly to the shop floor, making real-world formulation improvements. For instance, a grower in the delta region reported difficulty dissolving thiophanate-ethyl granules in hard water during the early spring. By forwarding those findings, we altered our wettable powder carrier ratios and eliminated common clumping problems. These stories, repeated across multiple cycles, illustrate that theoretical lab fixes only matter when they translate into reliable daily handling.

    Why Fungicide Resistance Remains Central

    Any field operator knows that resistance creeps in slowly, then all at once. One dry spell or poorly timed spray can send resistance markers spiking. Our product circumvents this pattern by interacting at more than one metabolic site in the fungal cell, making it much tougher for mutations to nullify the compound on a wide scale. Partner agents at research stations conduct monitoring trials for resistant pathogen populations, and we make that data public each season. This kind of transparency ensures that both large co-ops and individual farm managers can plan mixing regimes with actual local statistics, rather than broad guesses.

    Packaging and Accessibility for All Operation Sizes

    Some of our longest-standing clients run vast plantations, fitting out entire sprayer fleets. Others operate compact, family-run greenhouses or nurseries. We make sure the product lines reflect this diversity in scale. Bulk containers fill transport trucks for commercial users, but we pay attention to small pouch packs for local produce growers and cooperatives. This isn’t a marketing flourish—the logistical headaches for a home gardener are very different from those at an industrial sweet corn processor. Farm supply stores count on accurate, tamper-evident sealing and date marking to avoid confusion and product mixing in shared storage. Lessons from cooperatives taught us to prioritize handling ease, spill containment, and surplus storage, from transport delivery to daily on-farm use.

    Addressing Issues: What Still Needs Work?

    Every season, new pests and climate swings change the equation for both farmers and suppliers. Heat waves test the long-term shelf life of even the best-packaged batches. Extended rainfall raises runoff concerns near protected waterways. We see more questions about cumulative soil residues and pollinator safety. In response, our technical support team works with both internal chemists and independent labs to refine monitoring tools for customers. Looking forward, we are developing new formulations that degrade even more predictably across variable soils and climates, with efforts targeting both precision application and minimal ecological footprint.

    Keeping Trust: The Path Ahead for Grower Partnerships

    Our business remains built on the trust that comes from repeated success—not just the chemistry, but also the transparency when things require adjustment. People come to us with specific field problems, not abstract technical puzzles. That grounds our process improvements and reminds us that real-world reliability outpaces theoretical promise every time. Each new batch of thiophanate-ethyl reflects these lived experiences: focus on consistency, support for responsible use, and a willingness to learn from every season’s surprises. We look forward to continuing this direct dialogue with growers and industry partners, refining our chemistry and our commitment, season after season.