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Tetraoctylammomium Bromide

    • Product Name Tetraoctylammomium Bromide
    • Alias TOAB
    • Einecs 243-222-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    102849

    Product Name Tetraoctylammonium Bromide
    Chemical Formula C32H68BrN
    Molecular Weight 546.79 g/mol
    Appearance White to off-white crystalline powder
    Melting Point 62-66°C
    Solubility Water Insoluble
    Solubility Organic Solvents Soluble in chloroform, methanol, ethanol
    Cas Number 14866-33-2
    Boiling Point Decomposes before boiling
    Storage Conditions Store at room temperature, keep container tightly closed
    Density 0.98 g/cm³
    Pubchem Cid 25413

    As an accredited Tetraoctylammomium Bromide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Tetraoctylammonium Bromide, 100g, is packaged in a tightly sealed amber glass bottle with a hazard label and product details.
    Shipping Tetraoctylammonium Bromide is shipped in tightly sealed containers made of compatible materials, protected from moisture, heat, and direct sunlight. The chemical is classified as hazardous, so it must be handled according to relevant transportation regulations (ADR, IATA, IMDG), with appropriate labeling and documentation to ensure safe and compliant delivery.
    Storage Tetraoctylammonium Bromide should be stored in a tightly sealed container, away from moisture and incompatible materials such as strong oxidizers. Keep it in a cool, dry, and well-ventilated area, protected from direct sunlight. Ensure that the storage area is clearly labeled and access is limited to trained personnel to prevent accidental exposure or contamination.
    Application of Tetraoctylammomium Bromide

    Applications of Tetraoctylammonium Bromide in Industrial Manufacturing

    Tetraoctylammonium Bromide serves as a phase transfer catalyst and specialty reagent in highly controlled chemical processes. Its performance benefits specific industrial segments requiring efficient ion transfer, selectivity, and reliable process reproducibility.

    1. Agrochemical Synthesis as Phase Transfer Catalyst

    We supply Tetraoctylammonium Bromide in large volumes for use in the synthesis of crop protection actives, particularly for quaternary ammonium herbicides and specialty pesticides. Formulators utilize the material during the alkylation and halogenation of aromatic and heterocyclic compounds. By mediating ion exchange between organic and aqueous phases, the product accelerates reaction rates in the presence of strong bases and can reduce by-product generation. Close process control ensures consistent conversion and target yield. Downstream customers integrate this raw material at batch and continuous production scales.

    Industry compliance standards

    • REACH (EC 1907/2006) registration for agrochemical raw materials
    • OECD guidelines for Good Laboratory Practice (GLP) in pesticide active ingredient synthesis
    • ISO 9001 certified quality management system for intermediates
    • Compliance with US EPA regulations for chemical manufacturing

    Typical usage ratio

    • 0.1–2.5% w/w relative to limiting reactant, with exact rate set by catalyst recovery protocol and impurity profile control

    Downstream process integration

    • Added to multi-phase reactors before base addition
    • Standard in pre-mixing for mechanochemically active systems
    • Used in recirculated batch reactors with in-line extraction
    • Typically recovered and recycled for multi-cycle operations

    Final product types

    • Quaternary ammonium herbicides
    • Chloro-substituted fungicides
    • Pyridine-based insecticides
    • Pesticide intermediates for large-scale blending

    2. Pharmaceutical API Precursor Production

    Our Tetraoctylammonium Bromide is regularly procured by pharmaceutical manufacturers for the synthesis of APIs, particularly those involving nucleophilic substitution and halide exchange reactions. The material functions as a critical phase transfer agent, enabling precise control when working with moisture-sensitive precursors. Integration requires high purity and lot traceability. Process engineers utilize the product in both small molecule and complex heterocycle syntheses, including late-stage functionalization steps.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP and Ph. Eur. monographs for related pharma intermediates
    • FDA 21 CFR Part 211 for finished pharmaceuticals
    • ISO 9001 and ISO 14001 for production environment

    Typical usage ratio

    • 0.05–1.5% w/w based on substrate, adjusted to minimize residuals by validated cleaning

    Downstream process integration

    • Incorporated at the initial stage of nucleophilic displacement
    • Common in polar aprotic media with controlled water activity
    • Phase transfer step followed by in-situ quenching and wash
    • Trace residue monitoring per validated LC-MS method

    Final product types

    • Nucleoside analog APIs
    • Piperazine-based intermediates
    • Chiral pharmaceutical building blocks
    • Cytostatic agent intermediates

    3. Ion-Selective Membrane Manufacturing for Sensors

    Major OEMs in analytical instrumentation procure Tetraoctylammonium Bromide for production of ion-selective membranes. The compound serves as a cationic exchange partner and plasticizer in PVC or polyurethane film formulations. These membranes enable selective detection of potassium, sodium, and other ions in potentiometric sensors used for laboratory, clinical, and food chain monitoring. The material’s chain length ensures low membrane resistance and long-term stability, making batch-to-batch homogeneity a key QA parameter.

    Industry compliance standards

    • ISO 13485 for medical device component manufacture
    • RoHS Directive 2011/65/EU for electrical equipment
    • USP <661.1> Plastic Packaging Systems standards
    • ANSI/ISA-51.4 for sensor performance verification

    Typical usage ratio

    • 0.5–4% w/w in membrane phase, fine-tuned for optimal selectivity and drift control

    Downstream process integration

    • Mixed with polymer melts before casting membrane sheets
    • Emulsified in solvent blends with reference ionophores
    • Automated dosing for roll-to-roll coating lines
    • Membrane post-curing and QC by electrochemical calibration

    Final product types

    • Potassium ion-selective electrodes
    • Sodium ion sensors
    • Multiparametric water quality probes
    • Clinical electrolyte analysis chips

    4. Organic Synthesis of Specialty Surfactants

    Our plant supports surfactant manufacturers with Tetraoctylammonium Bromide for high-molecular quaternary ammonium surfactants and specialty emulsifiers. The material is used as a template ion in controlled synthesis of cationic surfactants, where selectivity and product purity impact emulsion droplet size and shelf-life. Real-time monitoring adjusts material feed rate based on in-process viscosity and surface tension measurements, ensuring the downstream product meets diverse performance demands from oilfield chemicals to personal care.

    Industry compliance standards

    • ISO 9001 and ISO 14001 at surfactant manufacturing sites
    • OECD 301B for biodegradability testing
    • Detergents Regulation (EC No 648/2004) for finished goods in Europe
    • Global Harmonized System (GHS) labeling for export compliance

    Typical usage ratio

    • 0.2–3.0% w/w based on total organic input, with dosing flexibility by surfactant alkyl chain length and charge density

    Downstream process integration

    • Dosed before quaternization step during batch synthesis
    • Employed in sequential addition mode for multi-head reactors
    • Blended post-reaction into final concentrate by inline static mixer
    • Lot released after comparative surfactant activity performance test

    Final product types

    • Cationic surfactant blends for oil recovery
    • Phase inversion emulsifiers for paint and coatings
    • Quaternary ammonium antistatic agents
    • Conditioning actives for industrial and cosmetic formulations

    5. Electrochemical Process Solutions

    Users in the electronics and energy sector rely on Tetraoctylammonium Bromide to formulate electrolytes for organic electrosynthesis and non-aqueous batteries. The compound acts as a conducting salt and stabilizer for organic solvent-based electrolytic cells, delivering high ionic mobility and suppressing electrode passivation. Formulators select specific particle sizes and trace impurity limits to achieve consistent current efficiencies and avoid trace metal contamination. Batch formulation undergoes tight control to satisfy specifications for cleanroom environment manufacturing.

    Industry compliance standards

    • IPC-6012 for rigid printed circuit board fabrication
    • IEC 62485-2 for safety requirements in industrial batteries
    • SEMI S2 for semiconductor tool/process safety assessments
    • UL 1973 listed performance for stationary energy storage

    Typical usage ratio

    • 0.1–2.0% w/v in electrolyte solution; adjusted to match cell gap, voltage profile, and solvent conductivity

    Downstream process integration

    • Premixed with aprotic solvent under inert atmosphere
    • Filtered for microfine particulates before cell fill
    • Dosed prior to electrode assembly in hybrid supercapacitors
    • Residual analysis pre- and post-cycling for electrolyte stability

    Final product types

    • Organic redox flow batteries
    • Electroplating baths for PCB via filling
    • Non-aqueous capacitor electrolyte packs
    • Printed electronics conductive inks
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    Competitive Tetraoctylammomium Bromide prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Tetraoctylammonium Bromide: Experience from the Source

    Looking Deeper at Tetraoctylammonium Bromide and Why We Make It

    There are a handful of specialty chemicals you learn to respect over decades on the manufacturing floor, and tetraoctylammonium bromide sits squarely among them. Here, making tetraoctylammonium bromide—known in industry as TOAB or TOABr—keeps us grounded in precision chemistry. Our process doesn’t just aim for purity on a page. Product consistency and the capability to tune the substance to specific laboratory or industrial requirements speak to why this quaternary ammonium compound holds a unique place in our lineup.

    Our model for tetraoctylammonium bromide maintains a high purity level, most batches running above 99% by modern analytic standards. Chemists seek out this grade for its reliability: there’s no guesswork about trace impurities undermining repeat reactions. Every batch owes its clarity to a strict multi-step purification process, something we’ve refined over years by responding to both feedback from research clients and our own analysis of trace cation-anion integrity.

    Working directly with this compound in the plant, you notice its solid white, crystalline form doesn’t tell the full story. Each granular, non-hygroscopic batch packs something special: a long-chain quaternary backbone that dissolves in both nonpolar and some polar solvents. Whether you weigh it by the drum or by the bottle, storage and handling prove much more forgiving than its shorter-chain analogs, which makes a real difference for customers who need stability over weeks, not just days.

    Producing Purpose, Not Just Product

    Day-to-day, most of our TOAB heads toward use as a phase transfer catalyst, especially for synthesizing complex organic and organometallic compounds. This isn’t just a chemical, it’s a facilitator—helping aqueous and organic phases communicate by shuttling the right ions across the interface. In our own facility trials, the difference between using a pure, well-controlled batch and a generic alternative shows up in yield and reaction rate. Chemists have sent us data comparing our TOAB against alternatives, and it’s always clear: better transfer, faster conversion, fewer side products that need cleanup.

    The demand for tailored application runs deep in catalysis. Electrosynthesis shops use TOAB in biphasic reaction schemes and find it offers unparalleled ion transfer compared to standard tetraalkylammonium salts with shorter or branched chains. That solubility in organic media, especially chlorinated solvents, scales up reactions without clouding the separation step—a secret our clients exploit to get cleaner isolated products.

    On the analytical side, electrochemists have found TOAB indispensable as a supporting electrolyte. There, purity and moisture sensitivity dictate everything. Electrodes respond much more predictably when impurity levels stay under control. Even seasoned teams with deep knowledge in polarography or nonaqueous cyclic voltammetry put a premium on the batch-to-batch reliability we insist upon.

    Side-by-Side with Alternative Quats

    Having handled nearly every possible quaternary ammonium bromide on the market, we’ve witnessed clear practical differences between them. Shorter-chain versions, like tetrabutylammonium bromide, dissolve readily in most solvents but create issues in extraction and clean-up for larger-scale reactions. The octyl chains in TOAB impart greater hydrophobicity, driving superior separation during biphasic catalysis. For customers in battery research or membrane fabrication, this hydrophobic profile translates to higher selectivity and stability in assembled devices.

    There’s another dimension too. Longer-chain analogs, such as tetrahexadecylammonium bromide, show significant viscosity even at moderate concentrations. That high viscosity complicates mixing, dosing, and filtration, making downstream equipment maintenance costlier. In our plant we target tetraoctylammonium bromide’s rare sweet spot—offering insolubility in water with controlled solubility in major organic solvents, without pushing the system into a sluggish, hard-to-pump regime. Extensive solvent testing at our site demonstrates that TOAB provides robust partitioning in everything from dichloromethane and chloroform to toluene and acetonitrile.

    Those familiar with the production floor recognize that not all quaternary salts respond the same way to temperature or humidity. TOAB remains stable and flowable where shorter-chain quats may clump, and longer-chain products risk forming waxy residues. Shelf life studies in our controlled storage facility reveal that containers of TOAB retain free-flowing quality even after several months’ exposure to typical warehouse conditions.

    Why Researchers and Industry Rely on Our Tetraoctylammonium Bromide

    In our conversations with process chemists, one message continues to rise above the rest: time wasted troubleshooting inconsistent input materials quickly eats up savings from cut-rate options. That lesson shapes how we manufacture. Every batch comes backed by verified compositional analysis, not just a one-time certificate but real sample-based proof.

    Commercial electroplating operations choose TOAB for precise control of ionic conductivity, a crucial factor when building up uniform metal films for semiconductors or functional coatings. Clients in medical device prototyping report that the use of TOAB in multi-layered sensor fabrication yields sharper, more reliable responses thanks to the absence of low-level impurities or unexpected trace ions. Teams in analytical chemistry find that our lots perform with lower background current, reducing false positives in detection regimes that have no margin for error.

    It isn’t just about what goes in, but what stays out. Each kilogram undergoes strict screening for residual solvents and by-products. Extensive testing in-house and at clients’ locations confirms that presence of as little as 0.01% contaminant can wreak havoc on a catalytic process or a sensitive measurement. Having invested in advanced purification columns and on-line analyzers, we bring a product that consistently stays well below threshold limits for these species.

    Meeting Changing Demands with Scalable Production

    The landscape for phase transfer catalysts keeps evolving. We’ve adapted our process to scale from kilogram pilot lots for research customers all the way to multi-ton batches for bulk industrial requirements. Unlike distributors who simply pass boxes along a chain, our team monitors every reaction—tracking yields, salt formation, and final product isolation. The goal is to remove surprises from the supply chain, and this hands-on approach makes all the difference.

    We have worked closely with industrial partners ramping up new polymerization or fine chemical synthesis lines. In these applications, repeatability is not an option; it is a requirement. A small impurity in the ammonium salt can produce batch failures or costly downtime. Our own plants have implemented strict feedback loops, pushing real-time analytics into each stage of the synthesis and crystallization process. From these controls come the high lot-to-lot consistency researchers and engineers now count on.

    Shipping to over 40 countries, we respond to variable logistics and remain agile for shifting regulatory standards. Having invested in tailored packaging solutions—drums for industrial clients, dual-sealed bottles for labs—we minimize risk of cross-contamination or exposure en route. Our technical team routinely works with regulatory affairs to furnish detailed compliance documentation upon request. Such traceability means there is no guesswork about source or quality, helping global manufacturers meet time-to-market and batch approval requirements without last-minute hiccups.

    Safety, Handling, and Real-World Support

    Years of hands-on shipping, handling, and production experience make one fact clear: well-made tetraoctylammonium bromide is not a major hazard when common industrial hygiene and storage practice are observed. We ship dozens of pallets each year; even then, each one earns its checklist status for air, ground, and maritime transit. Our operators follow strict personal protective equipment rules and track every drum, keeping spills and exposure rare. Customers often ask about shelf life or preferred storage. While the compound remains stable under ambient warehouse conditions, we advise keeping drums closed, dry, and out of direct sunlight for maximum performance.

    Feedback channels run both ways. End users sometimes report unexpected behavior—slower reaction rates, missed catalytic targets, or shifts in electrochemical signals. Instead of guesswork, we pull product samples and rerun tests, always inviting the customer’s technical staff to review our findings. That cycle of open, technical dialogue builds long-term trust, far stronger than any flashy marketing pitch. If new projects demand custom particle size, higher purity, or tailored packaging, real people here know how to address those challenges.

    Innovating Beyond Routine Supply

    Our manufacturing team constantly faces questions about the next horizon for quaternary ammonium compounds. Expectations change as new technologies, such as advanced battery storage, pharmaceutical precursor synthesis, or environmental catalysis, come online. We stay ahead by investing in targeted research and upgrading reactors, filtration, and drying systems in step with client needs.

    One area of emerging interest centers on using tetraoctylammonium bromide for nanoparticle functionalization. Surface charge modulation and stabilization remain critical when producing colloidal metal and semiconductor systems. In these high-tech fields, researchers care about controlling trace transition metal content or halide residuals. Our plant audits raw material sources and runs extended metal screening to keep downstream applications on spec.

    Sustainable manufacturing keeps gaining momentum in specialty chemical sectors. Solvent choice, waste minimization, and worker safety all get considered in our standard procedure reviews. When possible, we recover solvents on site and reduce water use, closing the loop to reduce environmental impact. Our partnership with researchers helps create tailored grades of TOAB suitable for green or solvent-free reaction media. Through joint pilot studies, we continue to push the application boundaries for this versatile phase transfer salt into cleaner, more efficient process chemistries.

    Comparing the Manufacturing Perspective: Lessons Learned

    Looking back over years of production and customer feedback, one point crystallizes: consistent, well-characterized tetraoctylammonium bromide pays dividends in every sector it serves. Cheaper or re-packed alternatives may appear cost-effective, but hidden variables—impurities, unknown batch histories, uncertain sourcing—can undermine entire projects downstream. Our own near-miss cases underscore this. Early third-party samples ruined an entire run of high-value ligand synthesis. We learned to invest in quality control, not just compliance, but performance analytics at every step.

    On the research side, stories keep arriving about failed extractions, inconsistent voltammetric readings, or product instability from off-spec batches. These events aren’t anecdotes, but case studies feeding straight back into our continuous improvement plans. Our technical support team documents each, updating internal protocols and sharing actionable insights with customers worldwide.

    Scale-up brings its own demands. Moving from gram-scale lab experiments to multi-kilogram reactor runs, even the most trusted quaternary salts can start to behave differently. During process development, technicians routinely test the same salt across a series of reaction scales, correlating particle morphology, nitrate/bromide balance, and drying kinetics with final product quality. These connections only come into focus after hundreds of pilot trials—a process we’ve refined by staying rooted in real-world experience, not just theory.

    Helping Customers Solve Tomorrow’s Chemical Challenges

    We believe manufacturing specialty chemicals means responding in real time to scientific and industrial evolution. Tetraoctylammonium bromide is not just a catalog item; for our company, it’s a dynamic material around which new ideas and improved processes gather. Surfactant makers, battery constructors, and research chemists return year after year because they trust our records—because every drum delivers as promised, or we make it right.

    If your next project needs high-purity, high-predictability tetraoctylammonium bromide, speak with us early. Our technical team stands ready to dig into specific protocols and develop a customized supply plan, not just drop a box off at your loading dock. Whether it’s ramping up for a giant R&D campaign, or solving an unusual solubility problem, long-term expertise built from sustained manufacturing puts us on your side.