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Tetramethylammonium Nitrate

    • Product Name Tetramethylammonium Nitrate
    • Alias TMA Nitrate
    • Einecs 223-974-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    790300

    Chemicalname Tetramethylammonium Nitrate
    Chemicalformula C4H12N2O3
    Molarmass 136.15 g/mol
    Appearance White crystalline solid
    Odor Odorless
    Meltingpoint 157-160 °C
    Solubilityinwater Very soluble
    Density 1.34 g/cm³
    Casnumber 506-97-8
    Boilingpoint Decomposes before boiling
    Ph Approximately 7 (aqueous solution)
    Stability Stable under recommended storage conditions
    Hazardclass Oxidizer
    Unnumber UN 3136
    Storagetemperature Room temperature

    As an accredited Tetramethylammonium Nitrate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Tetramethylammonium Nitrate, 100g, supplied in a sealed amber glass bottle with tamper-evident cap, labeled with hazard warnings.
    Shipping Tetramethylammonium Nitrate is shipped as a hazardous material due to its oxidizing and potentially explosive properties. It must be packed in tightly sealed, corrosion-resistant containers and transported under cool, dry conditions, away from incompatible materials. Proper labeling and documentation in accordance with relevant regulatory standards (such as DOT, IATA, or IMDG) are required.
    Storage Tetramethylammonium nitrate should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from heat sources, sparks, open flames, and incompatible materials such as strong oxidizers and acids. Protect from moisture and direct sunlight. Use non-sparking tools and ensure proper grounding to prevent static discharge. Store separately from combustible and flammable substances to minimize risk.
    Application of Tetramethylammonium Nitrate

    Applications of Tetramethylammonium Nitrate in Industrial Manufacturing

    Tetramethylammonium Nitrate finds application in specialized industrial sectors where its properties as a quaternary ammonium salt and nitrate source provide distinct process and formulation advantages. The following sections outline key downstream industries utilizing this raw material, detailing compliance requirements, formulation use rates, process placement, and the actual finished products manufactured with its integration.

    1. Ion Exchange Resin Synthesis

    Manufacturers use tetramethylammonium nitrate as a phase transfer catalyst and structure-directing agent in the production of anion exchange resins, particularly during the formation of macroporous frameworks. It enables precise control of pore structure and resin morphology when used alongside styrenic or acrylic monomers. The chemical is integrated in the polymerization bath or swelling solutions, influencing ion exchange capacity and selectivity, making it critical for producing high-performance resins for water treatment and pharmaceutical purification.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems
    • NSF/ANSI 61 for drinking water system components
    • EU Regulation (EC) No 1907/2006 (REACH) for chemical safety
    • FDA 21 CFR 173.25 for ion exchange resins in food processing

    Typical usage ratio

    • Ranges from 1.0% to 5.0% by weight of total monomer charge, optimized based on target resin bead size and porosity; adjustment depends on desired exchange capacity and flow rate properties.

    Downstream process integration

    • Added directly into the polymerization vessel during bead formation or introduced with the porogen mix prior to seed swelling and crosslinking steps.

    Final product types

    • Strong base anion exchange resins for municipal water purification
    • Packed bed ion exchange cartridges for pharmaceutical ingredient separation
    • Resins for sugar decolorization in the food industry
    • Specialty nuclear-grade resins for radioactive isotope removal

    2. Semiconductor Wet Etching Solutions

    The nitrate salt plays a selective role in engineered chemical etchants used in integrated circuit fabrication. Process engineers utilize tetramethylammonium nitrate as a modifier to adjust etch rates and minimize defect generation when processing silicon wafers, particularly in conjunction with other tetraalkylammonium compounds. Its inclusion enhances the anisotropy and precision of etching baths catered to advanced node device technologies, supporting strict cleanroom control and inline quality inspection in foundry and IDM environments.

    Industry compliance standards

    • SEMI S2 and S8 (Semiconductor Equipment and Chemicals Safety Guidelines)
    • IATF 16949 for automotive semiconductor suppliers
    • Cleanroom protocols per ISO 14644-1
    • RoHS (Restriction of Hazardous Substances Directive) for electronic components

    Typical usage ratio

    • Typically used at 0.2–1.5% v/v in mixed etch formulations; process engineers fine-tune concentrations based on wafer material and target etch depth.

    Downstream process integration

    • Blended into aqueous etchant solutions in wet benches or single-wafer etch reactors, supplied to process lines via automated chemical dispensers.

    Final product types

    • Finished silicon wafers for microprocessors and memory chips
    • Logic and sensor die for automotive and industrial electronics
    • RF device substrates for mobile communications
    • Photonic IC substrates for optical networking equipment

    3. Organic Synthesis Catalysis (Phase Transfer Catalysis)

    The compound is recognized for its efficiency as a phase transfer catalyst in multi-phase organic reactions, notably in the preparation of specialty quaternary ammonium intermediates and heterocyclic compounds. Research and custom chemical plants employ it to accelerate nucleophilic substitution and oxidation steps, using its solubility profile to improve mass transfer between organic and aqueous layers. This function has proven crucial for scalable production processes seeking higher yields and cleaner product streams.

    Industry compliance standards

    • GMP (Good Manufacturing Practice) for pharmaceutical intermediates
    • ISO 14001 Environmental Management in fine chemicals
    • ICH Q7 for API manufacturing controls
    • REACH registration for chemical traceability

    Typical usage ratio

    • Amount used ranges from 0.5 mol% to 5 mol% relative to limiting reagent; precise ratio depends on batch size, substrate solubility, and targeted conversion rate.

    Downstream process integration

    • Dosed into reaction vessels at the initiation of liquid-liquid or biphasic phases, facilitating substrate transport and enhancing interfacial reactivity during synthesis.

    Final product types

    • Active pharmaceutical ingredient (API) building blocks
    • Specialty heterocyclic compounds for agrochemical formulations
    • Custom quaternary ammonium salts for surfactant synthesis
    • Organo-catalyst intermediates supplying R&D laboratories

    4. Explosives and Propellant Formulation

    Industrial explosives manufacturers utilize tetramethylammonium nitrate as both an oxidizer and burn rate modifier in the formulation of non-primary energetic compositions. It is favored for preparing detonating cords, explosive boosters, and propellant blends due to its stability profile and reduced hygroscopicity compared to inorganic nitrates. Precise formulation control, purity level assurance, and traceability underpin its integration into closed, licensed plants operating under rigorous national and international standards.

    Industry compliance standards

    • ATF Explosives Law and Regulations (U.S. Bureau of Alcohol, Tobacco, Firearms and Explosives)
    • UN Recommendations on the Transport of Dangerous Goods – Model Regulations
    • ISO 9001 certified production with traceable batch records
    • European Agreement Concerning the International Carriage of Dangerous Goods by Road (ADR)

    Typical usage ratio

    • Employed in concentrations from 3% up to 15% by weight within energetic matrixes, adjusted according to blend-specific oxygen balance and desired energetic output.

    Downstream process integration

    • Mixed with plasticizers, fuel components, and other oxidizers in batch kneading or continuous blending lines immediately prior to extrusion, casting, or granulation steps.

    Final product types

    • Detonating cords for blasting operations
    • Propellant grains for industrial actuators and specialty mining charges
    • Boosters for commercial blasting cap systems
    • Customized energetic tablets for seismic survey devices

    5. Analytical and Research Reagents Preparation

    Laboratories engaged in advanced analytical chemistry and sample preparation deploy tetramethylammonium nitrate in the production of standard reagents and calibration solutions essential for ion chromatography, spectrometry, and trace element analysis. Due to strict purity and consistency demands, only controlled batches from validated sources are accepted, with rigorous documentation for trace contaminants and solution stability validated by accredited laboratories.

    Industry compliance standards

    • ISO/IEC 17025:2017 for laboratory accreditation
    • Ph. Eur. (European Pharmacopoeia) specifications for reference standards
    • OECD GLP (Good Laboratory Practice) for testing chemical substances
    • ASTM D4327 for water quality analytical methods

    Typical usage ratio

    • Prepared as stock solutions at 10–1000 ppm depending on analytical protocol and instrumentation sensitivity; further diluted at point of use according to calibration range requirements.

    Downstream process integration

    • Precisely weighed and dissolved using Class A volumetrics under laminar flow benches; integrated into analytical runs by automated sampler or direct operator addition.

    Final product types

    • Certified analytical standards for ion chromatography
    • Trace nitrate calibration solutions for environmental testing
    • Internal standards for ICP-MS trace metal measurements
    • Control samples supporting high-throughput industrial QA/QC labs
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    Certification & Compliance
    More Introduction

    Tetramethylammonium Nitrate: Engineering High-Purity Performance for Demanding Applications

    Our Direct Manufacturing Process and Technical Edge

    Tetramethylammonium nitrate (TMAN) stands among the specialty chemicals we manufacture with close control over every reaction stage. Our facility produces TMAN with a purity exceeding 99%, batch after batch, which means less worry about trace contamination and more predictable results in laboratory and industrial settings. We track every input—beginning with the reaction between tetramethylammonium hydroxide and nitric acid—monitoring pH, temperature, and feedstock quality. This hands-on approach yields a product that meets not only analytical grade benchmarks, but also the expectations of research chemists and process engineers who build their protocols around uncompromising consistency.

    Physical and Chemical Characteristics Matter in Daily Operations

    Our TMAN typically comes as a colorless to white crystalline solid or as a concentrated aqueous solution, with each batch subjected to spectroscopic and titration analyses. This level of detail straight from the source matters when customers rely on defined behavior. The high solubility of TMAN in water—well above many other ammonium salts—lets formulators and synthesis teams achieve more concentrated working solutions. The absence of cationic contaminants or residual metals ensures reactions perform as models predict.

    Handling properties also present distinct benefits. TMAN has a lower tendency to hygroscopically absorb atmospheric moisture compared to some other quaternary ammonium nitrates. That may seem like a small detail until you’re managing bulk solids that need to flow freely into reactors or blending vessels. As direct producers, we control the drying, packing, and sealing process, preventing caking and minimizing changes in batch performance between manufacturing cycles.

    Model Variants Respond to Diverse End Uses

    Different users require different formulations. We maintain several standard models defined by concentration and physical form. Some customers specify a solution at 40 wt% for automated liquid handling in analytical labs. Others require solid crystals with particle size distribution targeted for incorporation into energetic material blends. We offer ultra-high purity TMAN, with cationic and anionic impurity levels below the detection threshold of standard ion chromatography, used by electronics manufacturers pushing for ever-cleaner etchants and resist removers.

    For research community requests, we occasionally tailor physical specifications—crystal size, solution concentration, or water content—based on feedback rather than one-size-fits-all catalog products. Our R&D team reviews every such inquiry, looking for practical routes to deliver modifications without introducing batch-to-batch variability.

    Critical Application Areas—From Electronics to Organic Synthesis

    TMAN’s role stretches into several technically demanding applications. In the semiconductor and microelectronics sector, customers use our high-purity TMAN solutions for wafer cleaning and etching processes. The absence of metallic impurities matters when every sub-nanometer feature influences device yield and gate dielectric reliability. We focus on eliminating trace ions that might interfere with deposition or lift-off steps, since integrated circuit manufacturers cannot afford surface defects or conductive residues.

    In the pharmaceutical and fine chemical sectors, TMAN finds use as a phase transfer catalyst or as an efficient source of nitrate ions in selective oxidation reactions. Chemists have used TMAN to nitrate aromatic compounds and as an electrolyte in electrochemical organic synthesis—where high conductivity and lack of side-reactions are non-negotiable. Unlike many inorganic nitrate salts, TMAN dissolves rapidly and does not introduce interfering metal species, avoiding issues with residual heavy metals during scale-up.

    Energetics researchers, particularly those devising new propellant or explosive compositions, value TMAN’s oxidative properties in formulations where control over burn rate and gas evolution is necessary. In these roles, our TMAN brings a uniform particle size, consistent moisture content, and a purity level that supports reproducible test results.

    Product Differentiation—Why TMAN Stands Out Against Other Nitrates

    People often compare TMAN to ammonium nitrate or other quaternary ammonium salts, but distinct differences emerge for anyone working hands-on in the lab or factory. TMAN’s solubility and ability to deliver active nitrate ion without leaving alkaline or metallic byproducts gives it an immediate advantage in processes sensitive to contamination. It lacks the risk of introducing sodium or potassium that could interfere with high-precision synthesis or microelectronic assembly.

    Environmental handling also draws clear lines. TMAN is easier to neutralize in aqueous waste streams than many heavy metal-containing nitrates. Our production generates little inorganic salt byproduct, as we rely on clean-source reagents, and our in-house waste treatment reclaims water and removes trace organic residues, outperforming common environmental benchmarks for similar compounds.

    Compared to other members of the quaternary ammonium family, TMAN exhibits higher oxidative ability and reduced thermal volatility, which matters for engineers designing heat-based decomposition or redox-triggered reactions. We publish decomposition profiles and thermal safety data directly from our reactor runs, giving process teams the information needed to plan for safe storage and use at scale.

    Addressing Reliability, Safety, and Customer Feedback

    Direct communication with end-users is the backbone of our continuous improvement. We receive technical inquiries almost daily—about solubility limits at varying temperatures, how the product behaves under vacuum drying, or whether our TMAN outperforms imported material in specific etching baths.

    Our plant operates under a strict quality system, but we also look beyond certificates. We study how batches behave in real-world customer processes, seeking feedback on flowability, ease of dissolution, residue formation, and handling safety. One feedback cycle led us to modify our filtration setup, reducing ultra-fine particulates that previously caused filter clogging in automated systems. Similarly, enhanced packaging, with triple-sealed high-density polyethylene liners, grew out of transportation trials and customer guidance on how to reduce product degradation during summer shipping.

    Guiding Safer Handling Throughout the Supply Chain

    We manufacture TMAN with inherent safety in mind, but routine handling always requires respect for its reactive properties. We have learned through years of large-batch experience how to avoid accidental release, preventing both environmental events and workplace incidents. Every batch ships with a batch-specific lot number allowing traceability back to the precise reactor records—from raw reagents to packaging conditions.

    Our teams regularly meet to review incident reports, not only from our facility but from downstream users. By sharing anonymized case studies, we help users design safer storage, mixing, and disposal protocols. This type of operational openness has motivated labs and factories to request technical data sheets, stability data, and thermal decomposition profiles for their own risk assessments. We’ve even supported on-site safety trainings for customers scaling up their first TMAN process.

    Balancing Regulatory Demands With Application Growth

    Changing chemical regulations shape our product development every year. Nitrate-containing compounds increasingly fall under transportation, storage, and usage restrictions for security and safety reasons. We engineer our TMAN grades to fall below threshold concentrations that might trigger extensive reporting or handling requirements, while still meeting core performance needs.

    Because we produce at industrial scale, we monitor evolving environmental standards for effluent nitrate levels, ensuring our water and waste streams remain within local and international limits. Engineering safer, cleaner, and more easily handled forms of TMAN opens up collaboration with sectors—not only microelectronics and specialty synthesis, but also research fields exploring new energy sources or battery chemistries.

    Building for Long-Term Supply Stability and Partnership

    We recognize that research and production teams need more than a commodity; they need trust in supply. Over the years, we’ve built redundancy in our raw material procurement, put in careful buffer inventory, and doubled maintenance schedules for our reactors and packaging lines—so customers chasing critical deadlines avoid delays. We hold a “never shortcut” philosophy. That means running extra purity tests when a raw material shipment changes, or holding a batch until any result just outside specifications gets resolved.

    Customers—not midstream vendors—know we’ll answer the phone if a batch shows an unexpected shift in performance. Direct feedback from production chemists led us to offer small pilot batches for process validation before full-scale shipment, bringing a real-world approach missing from bulk chemical trading. We work through practical solutions when customers face last-minute specification changes or need technical documentation cleared with regulatory agencies, drawing on a deep bench of site chemists and compliance staff who have solved these challenges before.

    Committed to Transparency and Technical Depth

    We believe in supporting not just experienced buyers but also emerging researchers who may be handling TMAN for the first time. Years of hands-on manufacturing have given us insight into common stumbling blocks—like over-dilution, high humidity storage, or unintended cation contamination.

    We openly publish technical white papers and share results from our in-house labs—sharing not only methods that work, but also lessons learned from scale-up attempts or challenging purification runs. One of our greatest sources of pride is supporting graduate researchers troubleshooting reaction yields or startup teams validating next-generation electronic cleaning protocols. Honest dialogue has built a community of users that understand not only TMAN’s strengths but also its practical limitations in real-world applications.

    Shaping the Future of Nitrate Science and Manufacturing

    The world of nitrate chemistry continues to evolve. As new applications emerge—whether in green energy cycles, high-performance analytical chemistry, or advanced battery research—we work at the intersection of scientific innovation and hands-on process management. Our direct manufacturing line offers an assurance very different from commodity supply chains. We tailor, test, and refine every step, learning with our customers as they stretch TMAN into new directions.

    Our manufacturing philosophy grows from experience: clear communication, no shortcuts, and persistent attention to both chemical detail and application-driven results. That’s how we ensure each batch delivers not just specification compliance, but meaningful performance in the hands of real users. In this way, Tetramethylammonium nitrate represents more than a catalog entry—it stands as a handshake promise from manufacturer to user: that the science you build on it will be grounded in reliability and expertise forged by direct experience.