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Tetrafluorosuccinamide

    • Product Name Tetrafluorosuccinamide
    • Alias TFSA
    • Einecs 838-144-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    324401

    Chemical Name Tetrafluorosuccinamide
    Molecular Formula C4H2F4N2O2
    Molecular Weight 190.07 g/mol
    Cas Number 14047-28-0
    Appearance White to off-white solid
    Melting Point 142-146 °C
    Solubility Soluble in polar organic solvents
    Boiling Point Decomposes before boiling
    Density 1.65 g/cm3 (estimated)
    Structure Succinimide core with four fluorine atoms
    Synonyms Perfluorosuccinamide
    Smiles C(C(=O)N)(C(=O)N)(F)(F)F

    As an accredited Tetrafluorosuccinamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Tetrafluorosuccinamide, 25g: Supplied in a sealed amber glass bottle with airtight screw cap, labeled with hazard symbols and handling instructions.
    Shipping Tetrafluorosuccinamide should be shipped in tightly sealed containers, protected from moisture and incompatible substances. Transport at ambient temperature unless otherwise specified. Handle with appropriate personal protective equipment. Follow all relevant local, national, and international regulations regarding chemical transport and labeling to ensure safe and compliant delivery.
    Storage Tetrafluorosuccinamide should be stored in a tightly sealed container, protected from moisture and light. Keep it in a cool, dry, and well-ventilated area, separated from incompatible substances such as strong acids or bases. Store at recommended temperature, typically below room temperature, and follow all standard chemical safety guidelines to prevent decomposition and ensure safe handling and storage.
    Application of Tetrafluorosuccinamide

    Applications of Tetrafluorosuccinamide in Industrial Manufacturing

    Tetrafluorosuccinamide serves specialty roles across multiple advanced chemical sectors. As a manufacturer with scale capability in high-purity derivatives, we supply material that meets precise requirements in each application below.

    1. Advanced Polymer Synthesis for High-Performance Membranes

    Tetrafluorosuccinamide functions as a fluoroalkylating agent to introduce perfluoroalkyl groups into specialty monomers. Polyimide and polyamide membrane manufacturers use this material for improving chemical inertness, hydrophobicity, and thermal performance in filtration and electrolytic membranes. We support direct dispensing into solvent polymerization reactors, controlling addition rates for uniform copolymer structure. Quality control ensures conversion consistency and batch reproducibility.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems
    • ASTM D883 Polymer Terminology
    • REACH (EC) No 1907/2006 compliance for specialty chemicals
    • RoHS Directive 2011/65/EU for electronics-grade materials

    Typical usage ratio

    • 0.5% – 3% weight of total monomer mass
    • Adjusted based on desired fluorine incorporation and target membrane porosity

    Downstream process integration

    • Added during copolymerization reaction with base diaminomonomers and dianhydrides
    • Dissolved in NMP or DMAc solvent prior to polymer casting
    • Monitored for complete reaction by HPLC or NMR

    Final product types

    • Gas separation membranes for fuel cells
    • Ultrafiltration membranes for water treatment
    • High-temperature-resistant insulating films

    2. Pharmaceutical Intermediate for Targeted Synthesis

    Research-based pharmaceutical manufacturers utilize Tetrafluorosuccinamide as a building block to introduce fluorinated succinimide structures in small-molecule synthesis. The compound enables design of drug candidates with improved metabolic stability and binding affinity. We guarantee impurity control and custom particle size distribution for consistent reactivity in solid and solution-phase synthesis workflows.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • USP-NF specifications for permitted starting materials
    • FDA 21 CFR Part 210/211 for pharmaceutical production
    • Certificate of Suitability (CEP) if supplied into Europe

    Typical usage ratio

    • Stoichiometric or 10–30% excess relative to core structure, depending on coupled synthesis step

    Downstream process integration

    • Charge into protected amide coupling reactions in batch or flow systems
    • Purified by column chromatography or crystallization post-reaction
    • Monitored using HPLC and mass spectrometry for reaction completeness

    Final product types

    • API amide motifs with tetrafluorosubstituted succinimide
    • Fluorinated pharmaceutical intermediates
    • Lead compounds for clinical research candidates

    3. Specialty Electrolyte Additive for Lithium Battery Cells

    Battery cell manufacturers employ this material as a specialty additive for boosting oxidative stability and reducing side reaction rates in high-voltage lithium-ion electrolytes. Controlled addition during solvent blending raises cell cycling life and safety by stabilizing electrode-electrolyte interfaces. We supply grades validated by ICP-MS for transition metal impurity limits and water content below 50 ppm.

    Industry compliance standards

    • IEC 62660-2:2021 for lithium-ion batteries
    • UL 2580 for electric vehicle battery safety
    • ISO/TS 16949 quality management for automotive supply chain
    • China GB/T 31467 standard for battery cell safety

    Typical usage ratio

    • 50–300 ppm by weight of total electrolyte mass
    • Adjusted based on electrolyte solvent blend (EC, DMC, EMC proportions)

    Downstream process integration

    • Dosed into electrolyte solvent mix prior to cell filling
    • Dissolved fully by controlled agitation at room temperature
    • Mixed with LiPF6 or other lithium salt solutions

    Final product types

    • High-energy automotive battery packs
    • Consumer electronics battery cells
    • Grid storage lithium-ion modules

    4. Fluorochemical Intermediate for Agricultural Protection Agents

    Manufacturers of agrochemical actives employ Tetrafluorosuccinamide as an intermediate to create fluorinated succinimide substructures in crop protection molecules. The introduction of fluorine functionality enhances compound weather resistance, soil stability, and biological activity. Our facility meets trace contaminant controls for pesticide registration batch requirements.

    Industry compliance standards

    • FAO/WHO JMPR guidelines for pesticide manufacture
    • OECD Principles of Good Laboratory Practice (GLP)
    • U.S. EPA 40 CFR § 180–185
    • China GB 2763 requirements for pesticide residue limits

    Typical usage ratio

    • 1–5 mol% relative to the total heterocycle core or reaction stage

    Downstream process integration

    • Introduced during amide or imide ring-forming steps in active ingredient synthesis
    • Participates in nucleophilic substitution or acylation reactions
    • Reactant monitored by LC-MS and GC-analysis for reaction endpoint

    Final product types

    • Fluorinated fungicides
    • Selective pre-emergence herbicide actives
    • Novel insecticide intermediate scaffolds

    5. Etchant Component for Semiconductor Wet Processing

    Integrated circuit and display fabs utilize Tetrafluorosuccinamide in specialty etching baths designed for selective removal of photoresist and organometallic residues at the submicron scale. The compound functions as a stabilizer for acidic etchant blends, maintaining bath life and minimizing device surface defects. All lots undergo pre-shipment ion chromatography for particle and ionic impurity screening.

    Industry compliance standards

    • SEMI C93 Chemical Quality Standards for Etchants
    • IATF 16949 for automotive-grade microelectronics
    • RoHS 3 (EU 2015/863) for electronics safety
    • ISO 14644-1 Class 5 cleanroom compatibility

    Typical usage ratio

    • 0.1% – 2% by weight of total bath formulation
    • Fine-tuned according to silicon wafer process node and bath recirculation schedule

    Downstream process integration

    • Dosed directly into resist strip and post-etch wet cleaning baths
    • Homogenized with hydrogen peroxide and organic solvent systems
    • Automated inline dosing for critical process steps

    Final product types

    • Processed 200 mm and 300 mm silicon wafers
    • Flat panel display substrates
    • Photolithographic masks and reticles
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    Certification & Compliance
    More Introduction

    Tetrafluorosuccinamide: Reliability in Precision Chemistry

    Consistency matters most in specialty fluorinated chemicals. Through years of everyday production, I’ve seen one compound deliver time after time, earning trust in the labs and plants that depend on stability and tight tolerances: tetrafluorosuccinamide. As our daily output travels from our facility to research teams, battery manufacturers, or pharmaceutical labs around the world, it’s more than a molecule packaged and shipped out. For many chemists, it supplies rare confidence in outcome and a new angle for synthesis routes that used to feel closed off.

    What Our Teams Make: Directly From the Facility Floor

    Tetrafluorosuccinamide (CAS 71492-69-4) isn’t pulled from a catalog and repackaged. Every batch begins as a real process, under careful control, backed by chemists and plant operators tracking purity, byproducts, solvent residues, and storage conditions. Each drum and container bears the mark of a facility where robustness guides every reaction step. We’ve prioritized purity to guarantee that every lot falls within a narrow margin—over 99% by HPLC—because even a small contaminant can warp a reaction in specialty applications. Trace analysis governs every release, down to the parts-per-million for metal residues and moisture, since many partners build sensitive devices or synthesize precision compounds that fail when impurities sneak in.

    Model Numbers and Specifications: Real-World Details

    We follow a single main specification for tetrafluorosuccinamide, targeting a standard batch size for scale-up without complicating order fulfillment. Most shipments leave in 10 kg or 25 kg containers, with sample lots available for custom development. Chemical identification goes by our internal MF-7245, reflecting the streamlined process route we developed in close feedback with both battery and pharma customers. Melting point sits stable around 110°C, handled easily in standard dry rooms. Drying and storage happen in ultra-low moisture conditions to protect against hydrolysis. Our gas-chromatography and NMR validation methods catch the smallest structural or compositional drifts. This keeps each lot steady, round after round.

    In the Lab and on the Line: Uses for Tetrafluorosuccinamide

    We’ve watched tetrafluorosuccinamide’s journey from proof-of-concept in the lab to industrial adoption. Electrolyte researchers ask for it because its four fluorine atoms anchor extreme chemical stability, especially when exposed to corrosive lithium electrolytes. It solves a persistent problem: organic additives in battery slurries usually degrade fast or catalyze unwanted side-reactions, but the succinamide backbone resists this breakdown due to a strong C–F bond framework. This means less byproduct formation and superior capacity retention in cycling. For those scaling up battery packs, it brings relief from repeated cell failures and quality checks that chase elusive instability.

    Pharma teams appreciate the molecule just as much, but for a different reason. Tetrafluorosuccinamide offers a bridge between non-fluorinated synthetic intermediates and highly functionalized small molecules. Its high polarity and low steric hindrance let it act as a selective building block, particularly when trying to incorporate fluorine for improved metabolic stability or binding affinity in drug candidates. Feedback from R&D chemists points to clean reactions with limited side products, which shortens purification times and reduces solvent waste. Less waste means not just lower cost but also easier compliance with regional and international environmental restrictions—a factor that’s come up frequently in partner calls.

    What Makes Tetrafluorosuccinamide Distinct: Everyday Experience

    It’s easy to confuse tetrafluorosuccinamide with similar amide-based fluorinated compounds. Chemically, the difference sits in the substitution pattern—the molecule carries four fluorine atoms, offering a unique blend of hydrophobicity and high electronegativity. In our process, this structure shows off its advantages in yield, safety, and storage. Many older fluorinated amides require expensive special handling or have volatile byproducts that raise environmental controls. Our product, with a rigid backbone and lower volatility, poses little risk for off-gassing or pressure build-up—an outcome we fought hard to achieve through batch design and real-system monitoring.

    Customers have told us—straight from their lines—how production stops when less stable analogues start to decompose. Our variant sidesteps much of the premature aging seen with tri- or mono-fluorinated relatives. Temperature ramps demonstrate this durability, and measured pH shifts over storage intervals track much lower for tetrafluorosuccinamide. Fewer worries in the warehouse, fewer ruined glassware sets in development labs, and rarer QA call-backs for trace impurity spikes—that’s not advertising, that’s the result of seeing real-world returns year after year.

    Challenges and Our Answers: Meeting the Field’s Demands

    Supplying tetrafluorosuccinamide isn’t without challenges. Handling fluorinated compounds sometimes raises regulatory flags, especially where environmental trends target broader PFAS exposure. Not every fluorinated amide counts as persistent, and our teams developed a lifecycle analysis to document low environmental carryover and degradability under controlled hydrolysis. We support customers when audits or compliance reviews land on their desks; transparency in our own sourcing and waste-handling practices means partners can answer questions with confidence instead of scrambling for last-minute data.

    Shipping stability also takes work. The wrong packaging can allow trace moisture, setting off slow hydrolysis that only becomes obvious months later at the other end of the world. We developed reusable, lined metal containers that maintain sub-0.5% water, and we rotate inventory rigorously to avoid old stock. This reduces the need for partners to dry or reprocess material before use, which avoids line downtime and arms everyone with a more predictable input.

    Partnering for Process Development

    Rarely does a compound move straight from catalog to plant-scale process without adaptation. We recognize the hurdles in integrating a unique fluorinated intermediate like tetrafluorosuccinamide into long-standing synthesis chains. Over the last decade, we’ve worked side-by-side with partners, running custom reaction screens, feeding back impurity data, and adjusting lot sizes or solvent options to fit specialty reactors. Supporting scale-up doesn’t stop at a technical data sheet—it calls for actual response time and a willingness to talk through unexpected results. This attitude, carried by our technical service chemists, isn’t a sales pitch; it’s rooted in the daily reality of getting reactions to work at a hundred-liter scale instead of in a single flask.

    Safety teams in the field pressed us hard on handling instructions and spill control, which led to expanded in-house documentation on best practices, including secondary containment and waste recovery processes. We use what we learn from our own facility audits to provide detailed feedback to partners, allowing them to refine their MSDS and site safety manuals. These exchanges deliver real injury reduction and process improvements, proven by years of lost-time-incident logs both here and on our partners’ sites.

    A View from the Floor: Real Experience in Fluorination Chemistry

    The daily work with tetrafluorosuccinamide gives our people a front-row seat to shifts in the field. Battery chemists in Asia ask for stricter ppm-level sodium testing. Pharmaceutical researchers look for evidence of trace secondary amines. Industrial customers now prioritize transparency on sustainability and low-waste process validation. We answer these requests by removing unnecessary intermediates and choosing raw material suppliers whose own records track environmental responsibility. Every adjustment, from desiccant choices to NMR pulse calibration, echoes requests and lessons we hear from our actual production floor and our partners’ daily struggle to meet their own rising standards.

    Cost does matter at each turn—raw fluorinated feedstock swings hard on the global market. Our experience shows that quality and turnaround timing often outweigh theoretical price points. Partners get more value from a lot that yields 5 percent more final intermediate, cuts one purification pass, and avoids shipment delays. These aren’t theoretical, they’re real margin improvements logged by our accounts team and reported every month. By providing technical support alongside consistent product, we help customers hit targets in yield, process safety, and regulatory review rather than only chasing the cheapest per-kilo quote.

    What Sets This Product Apart

    For battery and pharma clients, there are always newer niche intermediates promising breakthrough yields or process benefits. Many drop out in the scale-up stage or introduce new sources of variability. Tetrafluorosuccinamide remains preferred when a project can’t afford the risk of failed stability or inconsistent supplies. The core differences: high-purity, documented batch-to-batch consistency, and technical backup that tracks beyond shipping. We hold ourselves responsible for every drum, from reaction vessel to shipping dock to delivery at the customer’s site.

    Partners reported fewer lot rejections and a reduction in end-of-line waste streams due to persistent impurities. Regulatory bodies responded positively to our open approach to documentation, which we attribute to our willingness to share not just what goes right, but what challenges arise during production—providing a track record, not just a promise. Whether the application asks for robust electrolyte performance or a selective intermediate in a multi-step synthesis, the margin for error narrows as industries set higher standards. Our approach is to face these requirements head-on, armed with process understanding and quality control grounded in practical experience, not conjecture.

    Supporting Long-Term Partnerships

    Every time a new inquiry hits our inbox, the process starts with a conversation about what actually matters to that end user—no two syntheses are identical. Customers shaping the next generation of batteries or seeking approval for a new pharmaceutical rely on clear parameters and quick response to changing needs. Our technical team tracks feedback and improvements suggested by long-standing clients, seeking patterns that allow us to refine procedures and introduce process upgrades ahead of regulatory or market-driven shifts. These close working relationships mean we can anticipate upcoming documentation requirements, analytical method changes, or shifts in material handling norms, allowing our partners to move projects forward without delay.

    Sustainability demands grow every quarter. We share life-cycle assessments and work toward continuous reduction in hazardous output, not because it’s a box to check, but because our operators and their families live near our site. Safe practices and long-term thinking preserve both our business and our community ties. Open reporting and active engagement with customer audits build trust, which is harder to earn than any certification stamp or cost saving. Direct feedback from our customers—flagging issues as trivial as off-labeling or as major as shipping delay—gets routed to real people, tracked, and followed up until fixed. This approach, borne out over thousands of lots, beats marketing claims each time.

    Looking Ahead

    Tetrafluorosuccinamide’s strong showing in battery chemistry paves the way for deeper adoption as energy storage tech continues to evolve. Our R&D group keeps a close eye on new cell designs and pharmaceutical scaffolds that call for unique properties—hoping to collaborate with research teams pursuing even more advanced formulas. Those looking to test new applications receive hands-on support, from tailored purification protocols to real-world packaging advice, which shrinks timelines and eliminates avoidable trial-and-error cycles for field chemists.

    We’re committed to tightening batch records, expanding application notes, and documenting real-world use cases directly in the feedback channels our customers prefer. Every improvement, every minor process tweak, is documented, validated, and communicated without layers of red tape or misdirection. This attention to detail builds real knowledge in-house and feeds a virtuous cycle of improvement that serves everyone handling tetrafluorosuccinamide—whether at the gram or ton scale. In a field where reliability and transparency have the most value, our experience and customer dialogue guide us forward.

    Conclusion: Chemical Manufacturing with Accountability

    Decades of production experience make clear that value comes from genuine consistency, attention to field needs, and a readiness to face challenges directly. Tetrafluorosuccinamide represents those priorities in action. Every batch, every container, reflects not just a controlled synthetic route but a daily commitment to real-world reliability—one that countless partners now see as indispensable. This is why the material stands as our most requested fluorinated specialty, why it stays part of innovation in both the energy and life science industries, and why those who use it come back for more—driven by their own field success, not by marketing spin.