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Tetraethylene Glycol Dibutyl Ether

    • Product Name Tetraethylene Glycol Dibutyl Ether
    • Alias TEGDBE
    • Einecs EINECS 203-977-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    211186

    Chemical Name Tetraethylene Glycol Dibutyl Ether
    Cas Number 143-24-8
    Molecular Formula C16H34O5
    Molecular Weight 306.44 g/mol
    Appearance Colorless oily liquid
    Boiling Point 346 °C
    Melting Point -62 °C
    Density 0.943 g/cm3 (20 °C)
    Solubility In Water Insoluble
    Flash Point 170 °C
    Refractive Index 1.435 (20 °C)
    Vapor Pressure 0.00042 mmHg (25 °C)

    As an accredited Tetraethylene Glycol Dibutyl Ether factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Tetraethylene Glycol Dibutyl Ether is packaged in a 500 mL amber glass bottle with a secure screw cap and hazard labeling.
    Shipping **Tetraethylene Glycol Dibutyl Ether** should be shipped in tightly sealed, chemically-resistant containers, away from incompatible substances, heat, and ignition sources. Transport in accordance with relevant local and international regulations, typically as a non-hazardous liquid, ensuring proper labeling and documentation. Protect from physical damage and always handle with appropriate safety precautions.
    Storage Tetraethylene Glycol Dibutyl Ether should be stored in a cool, dry, well-ventilated area away from heat sources, ignition, and direct sunlight. Keep the container tightly closed, made of compatible material, and clearly labeled. Avoid contact with strong oxidizers and acids. Store at recommended temperatures as specified in the safety data sheet. Prevent moisture ingress and ensure spill containment measures are in place.
    Application of Tetraethylene Glycol Dibutyl Ether

    Applications of Tetraethylene Glycol Dibutyl Ether in Industrial Manufacturing

    Tetraethylene Glycol Dibutyl Ether has established roles as a process solvent, phase transfer agent, and specialized carrier in selected high-value industrial sectors. Below, we present detailed application scenarios based on real downstream utilization, with information from our ongoing customer collaborations and supplier partnerships. Each sector description includes regulatory context, practical formulation guidelines, workflow positioning, and targeted final products.

    1. Lithium Battery Electrolyte Formulations

    This material serves as a high-boiling co-solvent and viscosity modifier in next-generation lithium-ion battery electrolytes, often used to support superior ionic conductivity, widen electrochemical stability windows, and improve low-temperature cycling performance. Industry leaders employ it in both prismatic and pouch cell manufacturing, primarily for electric vehicle and stationary grid storage applications.

    Industry compliance standards

    • GB/T 27664.1-2011 (Chinese lithium-ion battery electrolytes)
    • IEC 62660 series (International safety and performance standards for battery cells)
    • RoHS Directive 2011/65/EU (Restriction of Hazardous Substances in electronics)
    • ISO 9001:2015 (quality management in cell production)

    Typical usage ratio

    • 5–15% by weight of the total solvent system, adjusted according to target electrolyte viscosity, desired low-temperature performance, and salt solubility profiles

    Downstream process integration

    • Blended directly into lithium salt-containing organic carbonate base solutions prior to filtration, dehydration, and vacuum transfer into electrolyte filling stations at cell assembly lines

    Final product types

    • Automotive lithium-ion battery packs
    • Stationary energy storage modules
    • High-density portable electronics cells

    2. Grignard and Organometallic Synthesis Solvent

    Tetraethylene Glycol Dibutyl Ether finds use as a chelating ether solvent to support controlled Grignard and other reactive metal-based reactions, minimizing byproduct formation and enabling efficient heat management for sensitive pharmaceutical and fine chemical intermediates. Its excellent thermal stability and low volatility make it preferred in pilot to plant-scale continuous processing environments.

    Industry compliance standards

    • ICH Q7 (International Good Manufacturing Practice guidance for Active Pharmaceutical Ingredients)
    • US FDA 21 CFR 211 (Current Good Manufacturing Practice for Finished Pharmaceuticals)
    • REACH Regulation (EC) No 1907/2006 (solvent registration and safe handling)
    • ISO 14001 (Environmental Management System in chemical manufacturing)

    Typical usage ratio

    • 25–80% as the bulk reaction medium, with final ratios determined by solubility of reactants and thermal control requirements

    Downstream process integration

    • Charged to jacketed glass-lined or stainless steel reactors either as sole or co-solvent, present through reaction and work-up stages until solvent recovery/distillation during purification

    Final product types

    • Pharmaceutical building blocks
    • Specialty agrochemical precursors
    • Magnesium or lithium-based intermediates

    3. Microelectronics Photoresist Stripping Agent

    Microfabrication plants utilize this ether as a specialty stripping agent during the removal of advanced photoresists and polymer residuals on silicon wafers in semiconductor production. Its very low water miscibility and high boiling point offer enhanced performance in multi-stage batch and continuous wet process lines, particularly for sub-14nm node logic and memory device manufacturers.

    Industry compliance standards

    • SEMI S2 (Semiconductor Equipment and Materials International best practices)
    • IPC-CH-65B (Guidelines for Cleaning of Printed Boards)
    • ANSI/ESD S20.20 (Electrostatic Discharge Control)
    • ISO 14644 (Cleanroom and associated controlled environments)

    Typical usage ratio

    • 10–30% blended with proprietary stripping solutions, fine-tuned depending on resist thickness and bake protocol

    Downstream process integration

    • Introduced during wafer post-exposure cleaning and pattern development, followed by deionized water rinsing and drying cycles

    Final product types

    • Finished semiconductor wafers
    • DRAM and NAND memory chips
    • Power device dies

    4. Specialty Polyurethane Elastomer Production

    This glycol ether acts as a chain extender and internal plasticizer in cast and reaction-injection-molded polyurethane elastomer systems, particularly for applications demanding both high thermal stability and low temperature flexibility. Producers in transportation, heavy machinery, and industrial roller segments specify it for difficult-to-process polyol blends.

    Industry compliance standards

    • ISO 9001:2015 (Quality management in plastic and elastomer compounding)
    • ISO 4597-2 (Methods of test for urethane prepolymers)
    • EU REACH Regulation (substance registration and evaluation)
    • SAE J18 (Automotive elastomer specifications)

    Typical usage ratio

    • 3–12% of total reactant mass, optimized based on mechanical property targets and flexibility profile

    Downstream process integration

    • Dosed into prepolymer streams prior to mixing with isocyanates, facilitating uniform extension and plasticization during curing

    Final product types

    • High-durability polyurethane wheels
    • Custom industrial elastomeric rollers
    • Shock-absorbing pads

    5. High-Boiling Extraction Solvent in Specialty Chemical Purification

    The high boiling point and low reactivity profile enable use in selected extraction and separation steps for specialty organic chemicals. Refineries and fine chemical producers employ it to selectively recover polar organic compounds from non-polar hydrocarbon streams without introducing water, preserving yield in multistage extractive distillation set-ups.

    Industry compliance standards

    • API Standard 610 (Centrifugal pumps for petroleum, petrochemical, and natural gas industries)
    • ISO 9001:2015 (Quality in petrochemicals)
    • REACH and GHS compliance for solvent safety
    • Applicable local environmental discharge regulations

    Typical usage ratio

    • Variable, generally 10–40% of total solvent mass in extraction column charge; proportion set based on solute polarity and compartmentalization targets

    Downstream process integration

    • Added to extraction towers or mixer-settlers prior to phase separation, followed by solvent recovery via distillation or thin-film evaporation

    Final product types

    • Pesticide intermediates
    • High-purity hydroxy aromatics
    • Electronics-grade organic compounds
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    Certification & Compliance
    More Introduction

    Tetraethylene Glycol Dibutyl Ether: Value through Applied Chemistry

    Meeting Complex Needs with Purpose-Crafted Ethers

    As a chemical manufacturer with decades dedicated to high-purity glycol ether production, we understand there’s much more to Tetraethylene Glycol Dibutyl Ether than a line item in a catalog. Customers look deeper than a molecular formula. Each inquiry reflects unique requirements for solubility, stability, and reliability in demanding processes. The work done in our plants has always started with a direct understanding of these needs, refined through hands-on experience and close dialogue with industry partners. Across the years, Tetraethylene Glycol Dibutyl Ether has earned its place on our continuous production roster through careful optimization and a track record of solid, consistent performance.

    Specifications that Stem from Precise Manufacturing

    The success of a chemical like Tetraethylene Glycol Dibutyl Ether depends on more than theoretical purity. Batch-to-batch consistency, moisture control, and freedom from unwanted byproducts make the difference. In our experience, minor impurities can undermine whole production runs—especially in specialty applications that demand high solubility, low volatility, or extended shelf life. The product leaving our distillation columns and filtration units does not just meet purity thresholds; it works predictably in industrial syntheses. Specifications for water content, color, residual acids, and particulate contamination are checked batch by batch. The work isn’t glamorous, but it means producers relying on this ether see the same result each shipment.

    What Drives Demand: Chemical Functions and Industrial Roles

    Tetraethylene Glycol Dibutyl Ether fills a set of roles that narrower-range ethers and simple glycols cannot. Major uses turn up in lithium-ion battery electrolytes, reaction media for fine organic synthesis, and working solutions for specialty extractions. In lithium battery research, performance hinges on balance—solvents like this ether have to carry ions cleanly, withstand high voltages, and display chemical neutrality toward electrodes and additives. Our staff has worked alongside battery R&D lab teams to pinpoint blend ratios and additives that pair best with this ether, guided both by published data and hours in the plant optimizing distillation so no trace of reactive residuals remains.

    In the pharmaceutical industry, researchers look for solvents that gently dissolve challenging intermediates without reacting with them or breaking down under heat and pressure. Our direct conversations with process chemists tell us how frustrating it can be to lose process yield because a supplier skimped on their purification or let batches age too long in storage. By monitoring peroxide formation and oxidative stability throughout the warehousing lifecycle, we address those concerns at the source. Materials science sometimes brings even harder demands: for example, the need to control viscosity in polymer science or to support selective extraction. Tetraethylene Glycol Dibutyl Ether offers a high degree of polarity along with a long, undisturbed carbon chain, letting it serve as a compatible solvent in difficult environments where more common ethers break down or become too volatile.

    Building Confidence in Application: Feedback from Field and Lab

    Hands-on feedback has shaped our approach. Early on, we learned that off-the-shelf specifications don’t always solve real-world problems. We have reviewed customer pilot studies where Tetraethylene Glycol Dibutyl Ether faced down alternative ethers and co-solvents. Producers reported a smoother dissolution of lithium salts and fewer compatibility issues with separator membranes. For customers working in surface coatings, performance data shows how this ether imparts a lower evaporation rate than diethylene or triethylene analogues, reducing loss and enabling longer working times under factory conditions. We routinely sample and investigate application returns, checking both for contaminants and performance drift.

    The lessons go two ways. We discovered that longstanding storage or localized temperature swings can sometimes provoke trace decomposition or unpredictable reagent compatibility. By tightening drum capping protocols and auditor reviews, we traced and eliminated root causes, raising the bar for shelf stability by working at the point of manufacturing. Quality control teams draw on direct production experience, treating each batch as a distinct process rather than a faceless product.

    Comparison to Shorter and Longer Chain Ethers

    Tetraethylene Glycol Dibutyl Ether sits in a structural middle ground between the lower glycol ethers and bulkier polyethylene glycol derivatives. Users who transition from di- or tri-ethylene glycol ethers quickly notice improved resistance to volatility and more effective solubilization of certain salts and polymers. Longer chain ethers increase viscosity and slow mass transfer—useful for some niche extraction or separation techniques, but less welcome for precision coatings or mobile phase formulations.

    Higher molecular weight ethers also bring greater cost and tougher handling characteristics. Some projects, especially in analytical chemistry or electronics cleanroom work, demand a careful match of volatility, flash point, and solvency power. Our technical feedback loop involves direct testing, ensuring that end users do not pay for features they don’t need, or stumble into handling risks not present with shorter alternatives. Fire safety, environmental load, and downstream disposal practices are all factored into recommendations, avoiding one-size-fits-all “ether” advice.

    Regulatory and Environmental Attention in Chemical Supply

    Operating at plant scale means never losing sight of regulatory shifts. Glycol ethers have faced tightening scrutiny for emissions, persistence, and toxicity. Our compliance teams monitor changes in REACH restrictions, US EPA reviews, and regional updates from Asia and the Middle East. We stay at the table when new exposure data emerges or when end users raise questions about long-term impact. This is personal for many of our team members, some with family backgrounds in rural areas where waste streams matter. We decided to invest in closed-loop recovery—both to minimize plant losses and to support environmentally responsible partners.

    Analyzing wastewater and solvent residues, we’ve driven down losses over the years through iterative process improvements, strict loading and transfer procedures, and tailored waste handling. Any container leaving our facility has a transparent chain of custody, linking it back not just to a transaction but to a production event, a filtration cycle, and the QC run.

    The Value of Local and International Cooperation

    As a manufacturer who ships Tetraethylene Glycol Dibutyl Ether across continents, we never lose sight of the practical challenges at customs, in regional transportation, or in final on-site usage. European customers have flagged need for harmonized labeling, particular packaging types, or extra documentation matching national chemical registries. Asian clients raise questions about how the product holds up to local humidity swings or whether containers have been cross-contaminated in shipping. We respond not with generalized statements, but by sharing exactly how the product was handled, at what temperature it was loaded, and which raw material batches supplied that run.

    The value in these exchanges is mutual. Occasionally, a regional issue helps us improve globally—resulting in changes like enhanced secondary sealing on drums, new vapor barrier liners, or systematic logging of every cleaning cycle for container reuse. Large-volume buyers, including those in energy storage or advanced coatings field, frequently send technical teams to tour our facilities. We treat these visits as a chance to build understanding, not as a regulatory box to tick. Seeing the process firsthand reassures partners and stimulates new technical exchange.

    Innovation through Technical Partnerships

    Tetraethylene Glycol Dibutyl Ether’s capabilities continue to grow as field researchers, university labs, and private R&D teams put new ideas to the test. Partnerships like these matter to us. For example, after discussions in early-stage battery work, we were able to improve certain trace impurity specs, directly reducing cell failure rates in prototype lithium-ion formulations. Collaboration with polymer additive developers led to refinement of our filtration methods—resulting in fewer residual particles and smoother material blends.

    Our technical team has contributed to conference panels and shared anonymized data sets as part of industry forums on solvent access, purity, and alternative optimization. Years of producing this ether have taught us that openness about process and performance is more valuable than glitzy claims. True innovation demands mutual risk-taking: fine-tuning density, dielectric strength, or emission profiles based on test feedback, not committee reports.

    Challenges Ahead: Supply Chain Resilience and New Applications

    Markets for lithium-ion batteries, high-performance coatings, and specialty chemical manufacture face increasing pressure for adaptability. Feedstock variability—from price swings in ethylene to shifting byproduct markets for butanol—impacts not just costs but availability of the exact grade required. Political disruptions, as seen in recent years, can throw logistics into disarray, resulting in sudden shortfalls or delays.

    To meet these realities, we built redundancy into raw materials sourcing, added on-site storage, and strengthened logistics tracking. By forecasting customer demand not just by quarter but by upstream production rhythm, we’ve managed to keep supply flowing through bottlenecks that might hobble smaller operations. Our customers have direct lines to production managers—real people with authority to shift batch sizes or prioritize a critical delivery. We hold frequent planning sessions to review trends, anticipate demand spikes tied to regulatory shifts or project timetables, and orchestrate supply contracts that buffer both sides from market volatility.

    Some users seek help transitioning from older solvents facing regulatory sunset, or need advice on qualifying Tetraethylene Glycol Dibutyl Ether for their latest synthetic pathway. We do not limit support to generic handouts. Our technical and customer support teams are staffed by chemists familiar with the operational challenges and nuances of this ether in a production environment. We respond with direct knowledge, drawing on experiments and production records, not theory. When customers send samples back with questions, we review them using the same in-plant equipment and protocols that produced the original shipment. Over time, the investment in real troubleshooting has paid off—reducing waste, frustration, and optimizing long-term partnerships.

    A Perspective Informed by Experience: What Actually Matters

    Many chemical products promise outstanding purity and versatility, but the real test comes after shipment. Consistent product quality, honest communication, and the willingness to adapt differentiate partners from generic suppliers. Our history with Tetraethylene Glycol Dibutyl Ether is rooted in these principles. We encourage direct engagement—through factory visits, joint process trials, or hands-on discussions—because every customer’s application reveals something new.

    Advances in applied chemistry, battery development, and polymer science stretch the limits of what solvents can do. Each incremental improvement, whether in purity, stability, or logistical reliability, multiplies value for the researcher, processor, or manufacturer using this ether. From our perspective, manufacturing is not a static achievement but a living, evolving process. We have seen firsthand how attention to operational details, precise tracking, and open technical feedback add up—batch after batch, year after year. That history underpins every shipment leaving our facility, every new collaboration, and every commitment made to those depending on reliable Tetraethylene Glycol Dibutyl Ether.

    Addressing Tomorrow’s Technical and Environmental Needs

    Looking at the future of Tetraethylene Glycol Dibutyl Ether, fresh challenges await. Changing environmental regulations, more rigorous end-user demands, and ongoing shifts in international logistics all play their roles. As a manufacturer, we respond by investing in both people and process control; automation helps minimize operator error and waste while upskilling teams builds in the adaptability necessary to meet complex customer questions.

    Stricter disposal standards and scrutiny of solvent emissions mean each facility not only produces high-quality ether, but also limits environmental load. New filtration and recovery systems reclaim excess material at the source. We participate in collaborative industry efforts that share knowledge on best practices for waste minimization and resource efficiency. These investments raise both the social and the technical bar, reducing risk and expanding option sets for end users across industries.

    No chemical stands still. Tetraethylene Glycol Dibutyl Ether finds new applications as researchers discover what its combination of solubility, boiling point, and chain structure can accomplish. Each advance triggers new specification demands and fresh manufacturing controls. The relationships built with engineers, technicians, purchasing agents, and process chemists guide the product’s future—shaping its profile through practical feedback, not isolated lab tests. Our doors, laboratories, and processes remain open to that dialogue, committed to the continuous improvement that defines true chemical manufacturing.