Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

Suprofen

    • Product Name Suprofen
    • Alias Suprol
    • Einecs 254-015-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    713481

    Name Suprofen
    Chemical Formula C14H12O3S
    Molecular Weight 260.31 g/mol
    Drug Class Nonsteroidal Anti-inflammatory Drug (NSAID)
    Cas Number 40828-46-4
    Route Of Administration Topical (ophthalmic), Oral (discontinued)
    Mechanism Of Action Cyclooxygenase (COX) inhibitor
    Indications Ophthalmic use for inhibition of intraoperative miosis
    Appearance White to off-white crystalline powder
    Solubility Slightly soluble in water

    As an accredited Suprofen factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White plastic bottle labeled "Suprofen 100 mg," containing 100 tablets. The label includes dosage instructions, lot number, and expiration date.
    Shipping Suprofen is shipped in tightly sealed containers, protected from light, moisture, and heat, and clearly labeled according to chemical safety regulations. Transport is conducted by certified carriers, compliant with applicable local and international hazardous goods regulations to ensure the safety of handlers and the environment during transit.
    Storage Suprofen should be stored in a tightly closed container, protected from light and moisture. Keep it in a cool, dry place at room temperature, typically between 20°C to 25°C (68°F to 77°F). Ensure the storage area is well-ventilated and away from incompatible substances such as strong oxidizing agents. Keep out of reach of children and unauthorized personnel.
    Application of Suprofen

    Applications of Suprofen in Industrial Manufacturing

    Suprofen, a non-steroidal anti-inflammatory agent, finds targeted industrial application predominantly in pharmaceutical manufacturing and fine chemical intermediates. The nuanced characteristics of Suprofen support its integration in specialized fields, providing value exclusively where regulatory oversight, formulation specificity, and complex processing requirements drive demand. The use cases outlined below reflect actual industry implementation verified by compliance and downstream production parameters.

    1. Active Pharmaceutical Ingredient for Non-Steroidal Anti-Inflammatory Drug (NSAID) Formulations

    Suprofen is primarily used as an API in the large-scale manufacture of NSAID medications, specifically for ophthalmic and oral therapeutic preparations. Pharmaceutical plants integrate the compound at meticulously controlled dosages according to precise pharmacopoeial guidance to ensure consistent pharmacological results, with traceability enforced throughout processing. Downstream production lines require well-defined input specifications and tightly regulated process environments, as the material directly determines safety and efficacy of finished pharmaceutical goods.

    Industry compliance standards

    • U.S. FDA 21 CFR Part 211 – Current Good Manufacturing Practice for Finished Pharmaceuticals
    • European Pharmacopoeia (Ph. Eur.) Monograph on Suprofen
    • WHO GMP Guidelines
    • ICH Q7 – Good Manufacturing Practice for Active Pharmaceutical Ingredients

    Typical usage ratio

    • 0.05%–10% depending on the final dosage form (ophthalmic solution or oral tablet); precise loading determined by therapeutic dose and formulation matrix compatibility

    Downstream process integration

    • Direct addition during wet granulation or blending for solid forms, and as a critical input during sterile solution compounding for ophthalmic drugs; subject to in-process controls and validated cleaning steps

    Final product types

    • Ophthalmic anti-inflammatory solutions
    • Rx and OTC analgesic tablets or capsules
    • Pre-filled injectable syringes (in licensed markets)

    2. Intermediate for Synthesis of Chiral Pharmaceutical Agents

    Chemical manufacturers employ Suprofen as a precursor or chiral building block in the synthesis of more complex APIs, notably where the arylpropionic acid motif serves as a core structure. The manufacturing workflow incorporates this material in multi-stage organic synthesis, with process chemists calibrating reactions according to the required stereoselectivity and residual solvent limits, governed by GMP and ICH standards. In such applications, the intermediate must meet stringent impurity and trace metal content specifications to prevent downstream contamination.

    Industry compliance standards

    • ICH Q3A/B – Impurity Guidelines
    • EU GMP Part II for API intermediates
    • ISO 9001:2015 Quality Management Systems
    • Chinese Pharmacopoeia (where supplied domestically)

    Typical usage ratio

    • Varies from 0.1 to 2 molar equivalents per target molecule; adjusted according to reaction yield and downstream product purity requirements

    Downstream process integration

    • Charged as a feedstock at the initial or intermediate step of multi-step reactor synthesis, typically under inert conditions; followed by in-line or batch purification for isolation of downstream targets

    Final product types

    • Chiral intermediates for advanced pharmaceutical synthesis
    • Specialty APIs with modified propionic acid moieties
    • Fine chemicals for medicinal chemistry research

    3. Photoinitiator Precursor in UV-Sensitive Resin Formulations (Specialty Polymers)

    In advanced materials manufacturing, research-driven polymer plants utilize Suprofen in pilot and niche scale for development of novel photoinitiators embedded in UV-cured resins. The chemical’s aromatic ketone structure enables transformation into custom photoinitiator derivatives, which must pass safety reviews and structure-activity assessments per material application guidelines. Stringent photoinitiator purity and extractables/leachables compliance ensure suitability within consumer and electronics coatings sectors.

    Industry compliance standards

    • ISO 10993 for extractables & leachables (medical device coatings)
    • EN 14605 – Safety standards for polymer additives
    • RoHS (2011/65/EU) and REACH (EC 1907/2006) for electronic coatings
    • ASTM D6413 – Standard Test Method for Flame Resistance (if applicable)

    Typical usage ratio

    • 0.2%–1.5% by weight in photoinitiator synthesis reactions; dosage modulated for role as either primary initiator or structural diluent

    Downstream process integration

    • Incorporation by in-situ synthesis within reactor vessels for UV resin intermediate formulation; subsequently functionalized and blended into resin preparation lines

    Final product types

    • UV-curable coatings for electronics
    • Photoresist materials for PCB manufacturing
    • Specialty adhesives for precision optics assembly

    4. Analytical Reference Material for Pharmaceutical Quality Control Laboratories

    Pharmaceutical manufacturers and accredited testing labs depend on high-purity Suprofen as a reference standard for method validation, traceable quantitation, and batch release stability evaluation. This application requires supply of the material in certified, documented form, matching international standards for traceability and stability. Laboratory staff use the standard to verify method accuracy in content uniformity and to check system suitability, with reference values tightly aligned to compendial monographs and regulatory specifications.

    Industry compliance standards

    • ISO/IEC 17025 for laboratory competence
    • USP Reference Standards guidelines
    • Ph. Eur. Reference Substances program
    • FDA QSR 820 (when used for device component testing)

    Typical usage ratio

    • 5–50 mg per HPLC assay or stability analysis queue; actual aliquot determined by method sensitivity and calibration curve requirements

    Downstream process integration

    • Standard weighed and dissolved at point-of-use in analytical method validation protocols; used for assay of finished drug lots and in method transfer bridging studies

    Final product types

    • Certified HPLC/GC reference vials
    • Batch release qualification test kits
    • Stability study validation samples for regulatory filings
    Free Quote

    Competitive Suprofen prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Suprofen: A Trusted Choice from a Chemical Manufacturer’s Perspective

    About Suprofen and Its Roots

    The story behind Suprofen stretches back to the practical needs of industry and the lab. Developed to meet precise expectations for purity and reproducibility, this compound holds a respected spot on our production floor. Chemically identified as (±)-2-(4-isobutylphenyl)propionic acid, Suprofen crosses over from historical research into the heart of pharmaceutical and chemical synthesis projects. Each batch we create meets strict standards for identity and assay, ensuring tight control of impurities and minimal alterations from batch to batch. We do not see Suprofen as a generic entity but as a reflection of daily discipline in process control. Its white, crystalline appearance reassures experienced eyes, signaling the right handling and the correct synthesis practices.

    Specifications That Matter in Practice

    We manufacture Suprofen with a focus on its most critical specifications. Our standard grade offers a chemical purity exceeding 98%, with single-digit ppm levels for residual solvents and heavy metals. Water content rarely drifts from our low averages, minimizing risk for downstream reactions. The melting point remains consistent at about 193 to 194 degrees Celsius, speaking to well-controlled crystallization. Particle distribution matters here; consistent size improves measurement and operation in tableting and blending. Skilled operators monitor product color and clarity, catching even small deviations to avoid unpleasant surprises later on.

    Real-world customers rarely ask for fluff. Most want details about contaminants they care about most—aromatic impurities, acid/base residue, or oxidative byproducts. Our protocols bring quantifiable answers rather than vague assurances. The trust we gather comes from repeat business and problem-solving, not just glossy certificates.

    Why Suprofen Stands Out From the Crowd

    Comparisons between Suprofen and other arylpropionic acids take place almost daily in-house. Suprofen’s primary utility in ophthalmic pharmaceutical research separates it from the more common pain relievers like ibuprofen or naproxen. Its structure—particularly the phenyl ring substituted with an isobutyl group—drives selective cyclooxygenase inhibition, but with a different activity profile than alternatives. This influences regulatory handling and safety procedures during storage and transport. We pay special attention to cross-contamination. Equipment that handles ibuprofen, for example, follows one cleaning process. Suprofen receives stricter attention due to its specialized use.

    The difficulty in the final synthesis steps distinguishes it from less selective molecules. It demands greater vigilance in keeping enantiomeric purity under control if a customer requests a chiral variant, which adds complexity beyond what goes into mainstream NSAIDs. This is where bulk producers lose interest; the extra layers of quality challenge smaller outfits lacking modern analytical capabilities. Our facility runs HPLC, GC-MS, and chiral chromatography on each campaign, not once per month but every batch, to confirm specification points. It’s not glamorous work, but these checks turn up issues before any product leaves our site.

    End-Use Insights – Realities of Application

    Most buyers of Suprofen come from pharmaceutical laboratories focused on nonsteroidal anti-inflammatory drugs, or are developing analytical methods for drug metabolism studies. Our product feeds into research applications rather than blockbuster therapeutics, so each order represents a specific experiment or project. Customers return with feedback: how the compound performed in solution stability tests, whether they found unwanted byproducts, or how reliable the physical properties proved under tighter controls. We use that feedback to calibrate our own testing and batch documentation.

    Some formulations integrate Suprofen in ophthalmic drops, relying on dissolution behavior to ensure bioavailability. This draws attention to the solubility in buffers and organic solvents. Cheap feedstock does not cut it; high-grade Suprofen resists degradation under typical formulation exposures, holding true concentration levels for longer periods. Our teams push each batch to benchmark stability through forced degradation with UV, heat, or oxidizers. We publish these results for customers willing to dig deeper, helping them push their products through regulatory review with fewer surprises down the line.

    Researchers in academia and drug development leverage Suprofen as an internal standard for metabolic profiling against other NSAIDs. The consistency of our product—as proven by retention time and MS fingerprinting—carries value beyond numbers on a certificate. Failures in reproducibility drag out months of work. Human eyes on spectral data have caught one-off spikes, leading to root-cause investigations and process changes. It’s not always the kind of achievement that headlines a press release, but it’s the reason our partners trust our lots for reference purposes.

    Building Safety and Compliance Into Every Batch

    Chemical manufacturing means sleepless nights about compliance and safety. Suprofen’s toxicity profile differs from market mainstays; inhalation and skin exposure risks place it in a distinct category during handling. We do not rely just on paperwork. Engineers install local exhaust and containment, operators wear personal protection, and in-process checks monitor air quality during weighing and mixing. Any user who visits our facility will see active controls, not dusty safety posters. Quality and safety audits happen as much for our peace of mind as for outside authorities.

    Downstream packaging borrows lessons from real incidents—overpressurized containers, accidental spillage, missed labeling. Each lot faces a second check by experienced technicians who understand both language and layout. This extends to transportation partners. Suprofen travels with full documentation, chemical compatibility sheets, and spill management supplies, limiting the real-life fallout of rare mishaps. Our feedback loops run tight, so that one missed warning does not become a story on industry forums. This practical, frontline safety culture pays off in reliability for every link in the chain.

    Control of Impurities and Byproducts – No Margin for Error

    Experienced buyers know that a chemical’s certificate does not guarantee perfect results. Minor impurities can escalate into major headaches during scale-up or regulatory inspection. Suprofen invites extra scrutiny for aromatic byproducts due to the synthetic route. We maintain strict separation of vessels and piping. Incoming raw materials carry full traceability. Deviations in chromatography trigger repeat analyses and, if necessary, batch rejection. No one enjoys scrapping product, yet history teaches us that one shortcut in impurity monitoring makes for longer, costlier headaches during customer audits.

    Process chemists on our floor regularly update the synthesis route after learning which byproducts persist or elude routine QC. This ongoing process of improvement relies not just on high-level theory but on the lived experience of operators who understand where things can veer off course. Experience with scaling up from kilo- to ton-scale batches builds a sixth sense for what to watch out for: solvent switches, pH drifts, or recalcitrant residues from previous campaigns. We share these lessons with buyers interested in running their own secondary recrystallizations or purification steps, delivering hard-earned results rather than armchair advice.

    Adaptability for Evolving Research

    Suprofen’s biggest advantage may come from its adaptability. We field requests from molecular biologists looking to probe cyclooxygenase pathways, or from company pilot plants prepping for formulation runs in niche ophthalmic products. Suprofen blends into these needs because we maintain multi-scale reactors and flexible packaging suites. Sometimes that means running a single kilogram with special documentation for a partnership project. Sometimes it pushes our crews to produce hundreds of kilos for a global launch. Rapid turnover stresses infrastructure and staffing, but adds to the real-world credibility of claims about “customization.”

    Feedback from the field shapes our production timelines. If a biologist needs an expedited lot for an emerging program, we adjust campaign sequencing so that the relevant synthesis gets priority. If a regulator identifies a new trace impurity limit, we engage our analytical chemists in developing methods for tighter monitoring. This adaptability does not mean “anything goes”—it demands careful balancing of compliance, safety, and throughput. Every shift brings new learning, whether driven by technical requests or fresh regulatory hurdles.

    Materials Handling—Lessons from Daily Operations

    Hands-on handling of Suprofen teaches us lessons no datasheet could predict. The product’s granularity and flow characteristics determine packaging and transfer. We fine-tune powder transfer protocols to minimize airborne particle exposure and product loss. This attention to real-life handling prevents caking and clumping that would otherwise cost time and money down the line.

    Packaging solutions rely on experience—double-bagged polyethylene liners with tamper-proof seals stop both contamination and moisture ingress. Some customers request oven-dried lots, and we observe how Suprofen responds after transit in different climates to recommend whether vacuum packaging makes sense for their supply chains. Our technical staff tracks transit performance, not as an abstract exercise but as a risk management strategy.

    If Suprofen clumps in a humid warehouse, or particles break down under long shipping routes, we make those data points transparent to returning buyers. Openness about handling realities beats unexpected downtime or wasted process runs. Over years, our technical team logs every handling difficulty or success story, systematizing improvements to root out recurring bottlenecks.

    Economic Realities and Supply Chain Pressures

    Every batch of Suprofen gets shaped by economic realities just as much as chemical ones. Global supply chains never stay static. Sourcing precursor chemicals sometimes pushes lead times out or forces swift switches in approved vendors. We keep stock of qualified substitutions, so customers do not face sudden disruptions. Some manufacturers turn to cheaper but less controlled sources; our approach scales slowly, resisting shortcuts that might undermine quality. Every new supplier faces a full qualification process, including lab-scale test reactions and impurity mapping before full-scale production.

    Input costs fluctuate, pushing up manufacturing expenses. We choose to tolerate lower margins on at-risk contracts rather than risking performance with subpar raw materials. Our batch reports call out any variations in costs or lead-times to buyers, advocating for realistic scheduling rather than silent delays. This approach wins repeat business from partners who appreciate reliability above cut-rate offers. We share our own lessons about working with forecasts and inventory planning, helping customers weather stormy pricing periods with fewer shocks.

    Learning from Setbacks, Not Just Successes

    Suprofen production has not followed a straight line of expansion. We have encountered and solved material shortages, process inefficiencies, and failed batches. Rather than burying these problems, we bring them into technical reviews and risk assessments. Sometimes a lot runs out of specification, sometimes a packaging redesign is needed after a spill, or a new impurity fingerprint emerges in downstream analysis. Fast, open response to problems becomes the real mark of a working partnership in chemicals. We bring lab notes and incident reports to the table when discussing process improvements or repeated abnormal observations.

    We treat setbacks as catalysts to review and strengthen SOPs, cross-train staff, and enhance monitoring tools. Opening pilot batches to customer review offers shared learning and continual process optimization. We avoid blaming end users for unexpected findings, preferring to run joint investigations that benefit both sides. Each improvement cycle gets documented and shared, reinforcing supplier-buyer confidence that translates into practical, on-the-ground value.

    Partnerships Built on Credibility and Depth

    Control over Suprofen’s manufacture matters deeply to our team. Each day brings new validation data: in-house stability studies, impurity trend maps, comparison against secondary reference lots. We maintain unbroken lineage on certificate of analysis records, allowing full retrospection and confidence during audits. Customers expect more than just paperwork—they want evidence of real, audited traceability and a human commitment to full transparency about weaknesses and strengths.

    Practical partnership calls for sharing lessons about successful campaigns and setbacks. We invite technical teams from our buyers to review equipment, coral records, or even spot-check in-process controls. This handshake approach builds durable trust instead of relying on boilerplate sales talk. It also gives us early warning on market demand shifts and changing regulatory landscapes, helping us adjust batch runs ahead of direct requests. This way, we act as genuine partners in the development and maintenance of customer products, rather than faceless commodity sellers.

    Supporting Innovation Through Real-World Expertise

    The pace of pharmaceutical and chemical research continues to grow. We see new requests for Suprofen derivatives—esters, amides, or custom-labeled isotopic analogues. Feedback loops between our synthesis team and buyers accelerate turnaround for high-value projects, particularly where analytical standards or new APIs demand rapid response. Our approach looks beyond mass production, working with top researchers to develop custom routes or scale-up support for next-generation applications.

    We bring new staff into this work by sharing project histories, process data, and hands-on mentorship with seasoned production chemists. Deep expertise flows down into every batch, not just as institutional memory but as documented best practices. Training never ends at the level of a job description; it rolls forward in every scale-up meeting, project review, and customer debrief. The result is a product that adapts in real time to the needs of rapidly moving industries.

    Honest Conversations About Limitations

    The reality behind Suprofen’s performance includes not just highlights but honest discussion of limitations. Some customers test new formulations and encounter solubility or compatibility issues. Our commitment to open data-sharing supports smarter troubleshooting, reducing repetition and avoiding unproductive trial and error. We supply insight into reprocessing, purification tweaks, and secondary documentation that spares our partners unnecessary expense.

    If an unexplained out-of-specification event arises, both our team and the end user benefit from direct channels of communication. We encourage sharing detailed analysis outcomes and discussing lessons learned, supporting mutual growth. Problems somewhere along the line become opportunities to improve methodologies, not invitations for blame.

    The Human Element Behind Every Order

    Manufacturing Suprofen brings technical and operational demands, but at its core, it is a human process. Crews who work on charge preparation, crystallization, and packaging treat each batch as a reflection of their professionalism. Lessons pass on through shared experience—how to catch subtle color shifts, watch for telltale odors during synthesis, spot emerging contamination risks. This practice-grounded knowledge cannot be inserted by algorithm or automated checklist; it stems from years of focused attention and pride. End users benefit, because each order comes with a level of oversight and care shaped by real human investment.

    Suprofen leaves our site not just as kilograms of chemical, but as the outcome of collaboration between laboratory, operations, and front-line staff. Feedback—positive or otherwise—flows directly into process improvement rather than into a bottom drawer. Manufacturing teams view themselves as custodians of customer trust, not detached actors removed from downstream performance. Every improvement, tweak, and troubleshooting step funnels back into how we manage the next order.

    Looking Forward with Suprofen

    As research needs change and regulatory expectations evolve, we continue to invest in refining Suprofen production. Partnerships matter more than promotions; buyers return to proven suppliers who put substance over sales talk. We focus on practical control, continuous improvement, and honest dialogue about every stage—from synthetic strategy to end-use challenges. These priorities deliver Suprofen that meets more than a technical standard—it fits into real world applications with reliability, depth, and an unwavering commitment to safety and quality.

    Decades of experience prove that value comes less from showy features or price games and more from diligence, detail, and clear communication. This is the standard we maintain with Suprofen, batch after batch, year after year, as trusted partners to the scientific and technical community.