Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

Sulfisoxazole

    • Product Name Sulfisoxazole
    • Alias gantrisin
    • Einecs 203-813-0
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    356929

    Generic Name Sulfisoxazole
    Brand Names Gantrisin, Truxazole
    Drug Class Sulfonamide antibacterial
    Molecular Formula C11H13N3O3S
    Molecular Weight 267.30 g/mol
    Mechanism Of Action Inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid
    Route Of Administration Oral
    Indications Treatment of urinary tract infections, otitis media, and other susceptible bacterial infections
    Contraindications Hypersensitivity to sulfonamides, infants less than 2 months, severe liver or kidney disease
    Side Effects Rash, nausea, vomiting, headache, allergic reactions

    As an accredited Sulfisoxazole factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Sulfisoxazole is packaged in a white, opaque plastic bottle containing 100 grams, with a tamper-evident cap and detailed labeling.
    Shipping Sulfisoxazole is shipped in tightly sealed containers, protected from light, moisture, and extreme temperatures. It is typically handled as a non-hazardous pharmaceutical compound but requires secure packaging to prevent contamination. Compliant with applicable regulations, the shipment is labeled clearly, and documentation is included to ensure proper handling and safe delivery.
    Storage Sulfisoxazole should be stored in a tightly closed container at room temperature, ideally between 15°C and 30°C (59°F and 86°F). Keep it away from excessive heat, moisture, and direct light. Store in a dry, well-ventilated area, separate from incompatible substances. Ensure the storage area is secure and access is limited to authorized personnel to prevent accidental exposure or misuse.
    Application of Sulfisoxazole

    Applications of Sulfisoxazole in Industrial Manufacturing

    Sulfisoxazole is a sulfonamide-based chemical raw material with primary use in pharmaceutical formulation and related specialist industries. We support clients globally who require tight process control, validated regulatory compliance, and strict product integrity across several distinct industrial sectors. Below, we break down verified downstream application tracks and their corresponding requirements for the effective and compliant use of Sulfisoxazole in modern manufacturing.

    1. Oral Solid Dosage Pharmaceutical Manufacturing

    Pharmaceutical manufacturers use Sulfisoxazole as an active pharmaceutical ingredient (API) in tablets, capsules, and pediatric suspensions targeting gram-negative and select gram-positive bacterial infections. Upstream, our bulk material undergoes full compendial testing prior to release. In production, formulators commonly pre-mix Sulfisoxazole with excipients such as lactose or microcrystalline cellulose, adding disintegrants and binders as prescribed by the specific monograph or in-house formulation plan, all under GMP protocols. Tablet presses and encapsulation lines require API that meets dosage uniformity, particle size, and moisture criteria for homogenous blending and physical stability through compression or encapsulation cycles up to packaging.

    Industry compliance standards

    • Ph. Eur., USP, JP monographs for Sulfisoxazole
    • ICH Q7 GMP guidelines
    • 21 CFR Parts 210/211 requirements
    • FDA/EMA DMF referencing and validation protocols

    Typical usage ratio

    • 250–1000 mg per oral dose, adjusted by final dose strength—API typically comprises 20–60% of tablet/capsule core blend by weight

    Downstream process integration

    • Direct addition during blending step of tablet or capsule core mass; shifts to wet or dry granulation as required by target dissolution profile and regulatory submission

    Final product types

    • Film-coated or sugar-coated tablets
    • Hard gelatin capsules
    • Pediatric suspension powders for reconstitution

    2. Veterinary Antimicrobial Premix Production

    Sulfisoxazole is used by veterinary pharmaceutical companies integrated into feed premixes or direct-application powder sachets for swine, poultry, and cattle. Our supplied raw material must comply with VMD, CVM, and country-specific veterinary standards. It enters the blending tanks alongside carrier materials like dextrose or silicate flow agents. The mixing process involves intensive monitored blending for homogeneity, followed by granulation or spray-drying if a stable premix or dispersible powder is needed. Attention is given to uniform dose delivery in finished feed or diluted drench applications. Resistance monitoring requires precise adaptation to restricted usage patterns and withdrawal times.

    Industry compliance standards

    • European Pharmacopeia and USP standards for veterinary use
    • Good Manufacturing Practice for Veterinary Medicinal Products (EU GMP Vol 4, Annex 5)
    • FDA Center for Veterinary Medicine (CVM) criteria
    • VICH GL9 pharmacovigilance guidelines

    Typical usage ratio

    • 5–10% w/w in medicated premix; field application rates of 13–60 mg/kg body weight in finished feed or water, adjusted by species and label claims

    Downstream process integration

    • Dry blending with carrier matrix, then batch granulation, sieving, and QC; direct fill into foil sachets or drum containers; samples retained for stability and residue monitoring

    Final product types

    • Medicated feed premixes
    • Oral powder sachets
    • Water-soluble veterinary preparations

    3. Topical Antimicrobial Cream and Ointment Manufacturing

    Manufacturers of topical pharmaceutical products incorporate Sulfisoxazole into sterile, non-irritant creams and ointments for dermal infection and minor wound care. Raw material requires microbiological and heavy metal testing prior to use. The API enters during the heated emulsification phase, typically post-melt, to prevent degradation. The formula contains oil and water phases, with Sulfisoxazole dispersed to achieve precise concentration and even particulate distribution. Rheology modifiers stabilize the final ointment or cream consistency. Finished lots undergo preservative efficacy testing and compliance with topical product shelf life validations.

    Industry compliance standards

    • USP/NF specifications for topical preparation
    • 21 CFR Part 333–Topical antimicrobial regulations
    • Good Manufacturing Practice (21 CFR 210/211)
    • EU Cosmetics Regulation exclusion (ensured medical/pharma registration)

    Typical usage ratio

    • 1%–4% API by weight in ointment or cream base, aligned with clinical indication

    Downstream process integration

    • Hydration and pre-dispersion of API with stabilizer in oil phase or aqueous phase (depending on emulsion type), followed by emulsification or suspension pre-packaging or tube filling

    Final product types

    • Topical healing ointments
    • Antimicrobial skin creams
    • Combination first-aid wound care products

    4. Bulk Sterile Powder for Injectable Reconstitution

    Hospital product manufacturers utilize Sulfisoxazole in the production of sterile powders for parenteral reconstitution. The manufacturing environment must uphold ISO 14644 cleanroom standards, and all starting materials must meet pyrogen and bioburden specifications. Sulfisoxazole is dissolved or suspended in a sterile vehicle, subjected to precise lyophilization or vacuum drying, and filled into vials or ampoules under aseptic conditions. Each lot undergoes finished product particulate testing, endotoxin determination, and stability protocol alignment with hospital procurement requirements.

    Industry compliance standards

    • USP/NF Injectable drug standards
    • USP <797> for sterile compounding
    • European GMP Annex 1 for sterile medicinal production
    • WHO Good Manufacturing Practice for sterile pharmaceuticals

    Typical usage ratio

    • Direct formulation at 1–3 g per sterile vial, dependent on clinical dosing schedules and hospital formulary

    Downstream process integration

    • API addition post-filtration in sterile blending vessel, followed by lyophilization or sterile vacuum drying and aseptic filling into glass vials

    Final product types

    • Sterile lyophilized powder vials
    • Powders for hospital pharmacy reconstitution
    • Bespoke parenteral formulation kits for clinical use
    Free Quote

    Competitive Sulfisoxazole prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Sulfisoxazole from the Manufacturer’s Bench

    The Workhorse of Sulfonamide Antibiotics

    Behind every lot of Sulfisoxazole leaving our facility stands decades of real-world production experience. It is a comfort to those in the medical and veterinary fields, reliable as a solid core in the long line of sulfonamide medicines. Our manufacturing lines do not chase after passing trends; they do what matters—deliver Sulfisoxazole with consistently high purity, low impurity profiles, and reliable quality with every shipment.

    Why Sulfisoxazole Still Matters

    Ask any seasoned pharmacist or formulator where Sulfisoxazole fits, and you will get a practical answer: foundational infection-fighting power in tablet or suspension forms for bacterial infections, mainly in the urinary tract. Not as flashy as newer molecules, but in clinics, animal feeds, and resource-limited health programs, the world still counts on Sulfisoxazole as a workhorse. Hospitals that know the patterns of urinary tract pathogens still pick this active ingredient because old problems often stay stubborn.

    Specifications: From Raw Powder to Dosed Tablets

    Exact measurements matter in our line of work. Typical production batches reach content standards not just for high assay (over 99% is standard for us) but also for strict controls on moisture content, particle size, and microbiological purity. Recrystallization, thorough drying, and repeated quality checks take time, but the result is a powder ready for direct tablet pressing or blending into suspension formulations. Customers in both human and veterinary segments tell us how much they value a product that blends evenly, coats properly, and meets dissolution rates for reliable bioavailability.

    From the Chemist’s Perspective

    Chemists here see each lot from raw sulfanilamide through the delicate process of heterocyclic ring formation and eventual crystallization. It’s labor—you coax the right crystalline structure into existence under tightly controlled temperature, pH, and solvent conditions. Experience guides us in reading the color, the feel of the slurry, and the subtle cues from chromatography. Crafting the difference between a subpar product and a pharmaceutical-grade Sulfisoxazole makes the difference between recovery and prolonged infection for the end patient.

    Tracing the Differences: Sulfisoxazole vs. Other Sulfonamides

    Among the whole class of sulfonamides—Sulfamethoxazole, Sulfadiazine, Sulfamethazine, and others—Sulfisoxazole stands out for its balance of fast urinary excretion and relatively mild side effect profile. Some of our oldest clients say it clears up acute cystitis cases promptly yet washes out of the system fast enough to avoid stubborn residue. Unlike Sulfadiazine, which tends to linger and can crystallize in the bladder, Sulfisoxazole passes through more quickly. Compared to Sulfamethoxazole’s longer action, Sulfisoxazole moves on, often reducing the risk of complications from drug buildup.

    From the manufacturer's side, we appreciate these functional differences. They shape how physicians choose one molecule over another, how pharmacists set up their stock, and how regulatory officers look at reporting requirements. That is why our lines keep the specifications tailored to the molecule's known metabolic path—no shortcuts here, no confusing blends with other actives. Sulfisoxazole deserves its own proper space on the production line for a reason.

    Market Shifts and Pressures

    Over the years, pressures mount from all sides. Some new antibiotics draw the public's attention, and certain countries shift their registration standards. Yet field clinics, veterinary hospitals, and bulk antibiotic buyers keep our order board healthy. Sulfisoxazole remains less expensive to produce compared to next-generation molecules. The cost-control story matters a lot to field doctors buying in bulk and to governments running big infectious disease programs.

    We do not see Sulfisoxazole as an “old-fashioned” product but as a dependable tool that outlasts hype. It is recorded as an essential medicine by various health organizations, especially in settings where broad-spectrum, oral therapy is needed without breaking procurement budgets. Production doesn’t carry the same environmental and high-pressure reactor burdens as some newer antibiotics—a point our environmental control team notes as a win.

    Sulfisoxazole’s Place in Formulation

    Pharmaceutical companies order Sulfisoxazole in bulk for pressing into scored tablets, gel caps, or for dry suspensions aimed at pediatric and veterinary use. Because we keep the bulk powder free-flowing and maintain tight granulometry, the product fills accurately and mixes well with flavoring agents, starches, or even non-sugar excipients. Suspension makers praise the consistency batch to batch; they do not have to second-guess our lot numbers or tweak their SOPs every time a drum rolls in.

    We hear the same from developers working on combination therapies. They count on us to deliver Sulfisoxazole cut to their particle size needs—not too fine to cause dusting and too coarse to delay dissolution. These are practical matters on busy production floors, not just statistics for a technical specification sheet.

    Batch Release: Real-World Quality Control

    From decade to decade, regulators push new guidance—lower thresholds for microbial count, stricter limits on related compounds, and clearer chromatographic signatures. Our QC unit responds with daily checks on raw materials, intermediates, and finished Sulfisoxazole. Chromatograms tell the truth: the peaks for impurity A, B, or C only barely register.

    Some customers ask for additional certificates, or further checks for specific countries, and with years under our belts, we handle those without holding up deliveries. Batch records trace back every kilogram to raw stock and operators. Labs enforcing compliance on tough standards for solvents, heavy metals, and pyrogens do not surprise our teams. These controls are the backbone of repeat orders and solid customer trust.

    Packaging with the Formulator in Mind

    Every packaging line aims to keep the integrity of the batch and minimize product loss. We choose packaging types—double-layered bags, robust drums, and clear tamper-evident labeling—based on how well they defend against humidity, temperature swings, or warehouse mishaps. For custom runs, we print lot and expiry data directly on the bag so there’s no confusion during your receipt or in the middle of a busy plant shift.

    Veterinary Sector Demands

    The veterinary side still places high-volume orders for Sulfisoxazole, both as a standalone agent and—more often—in combination with other sulfonamides. Feed producers mix it in formulations that deliver rapid results in poultry and swine. Speed matters in livestock health, and Sulfisoxazole’s pharmacokinetics fit short withdrawal times, which producers appreciate. We adjust packaging for field mixing—no caking, no hard lumps—even after cross-country truck rides.

    Our work with veterinary science teams pushes us to refine our product form for direct dissolution in water, and further testing under variable farm conditions. From the comments we hear at trade shows and in follow-up calls, reliability in dosing puts our Sulfisoxazole a step ahead, especially when the stakes are high for entire flocks or herds.

    Regulatory Attention and Compliance

    Every batch runs through a battery of in-house checks before clearing for shipment. Authorities in more than a dozen countries have visited our site, scrutinizing environmental management, batch logs, and employee training records. Our compliance department keeps ahead of changing guidelines on sulfa drug residues, producing test results for both raw and finished Sulfisoxazole.

    Some countries demand full documentation for each shipment, down to the original batch number of the starting sulfanilamide. Transparency in the paperwork lines up with our open-door policy during onsite inspections. We aim to keep regulators confident in our chain of custody and customers reassured that what they order matches precisely what arrives on their dock.

    Environmental Stewardship

    Manufacturing Sulfisoxazole on a meaningful scale means respecting the chemicals we handle. Our team oversees every wastewater stream, recovers solvents where possible, and ensures compliance with both national and international environmental standards. That means investment—in updated scrubbers, better containment, and energy monitoring.

    Our experience tells us that any shortcut today means a regulatory problem or expensive cleanup tomorrow. The local community scrutinizes our emissions, and tracking improvements in waste reduction reflects our shared responsibility as chemical manufacturers. Some of the batch yield gains actually come from smarter resource management.

    Innovation Inside a Classic Process

    Some say no one innovates on old molecules. We disagree. Over the years, our teams have refined crystallization controls, reduced internal rejection rates, and trimmed solvent usage per ton of Sulfisoxazole produced. Those steps make a difference—customers see fewer complaints, and our line runs interruption-free longer.

    A key improvement came with real-time data logging, allowing us to spot drifts in crystallization times or microcontaminant upticks before a single kilogram leaves the facility. These aren’t just technical tweaks; they preserve the medic’s trust in the tablet or syrup poured for patients day in and out. Improvements we make ripple out to better downstream QC for our buyers.

    Supply Chain Adaptability

    The health supply world does not wait for perfect conditions. Earthquakes, pandemics, currency swings, and government contract changes force supply schedules and logistics daily. Our warehouse staff has shifted shipments to remote locations, split containers by special request, and handled bottlenecks when transportation delays hit.

    We see ourselves as partners, not simply anonymous suppliers. That means keeping honest timelines, warning buyers if weather slows a shipment, and assembling loads for maximum product preservation. Our consistent order fulfilment keeps not only our clients running but also the patients relying on their end products.

    Responsibility toward the End User

    Behind every drum of Sulfisoxazole stands a line of workers who know their product could turn the tide in someone’s infection. We understand where the powder ends up—drug stores in small towns, relief clinics in remote villages, veterinary hospitals with limited alternatives. The trust built up with each lot shapes repeat business and personal connections formed across borders.

    Many of our partners have run their plant checks, seen the lab trails, and brought home the difference that strict quality brings. We keep data open, respond with transparency, and adjust as regulations or customer demands evolve. Our pride comes from knowing real people benefit from our attention to detail.

    Sustainable Production in a Changing World

    The world’s antibiotic needs grow and shift, but old diseases linger and demand steadfast solutions. Producing Sulfisoxazole at high standards, we accept the challenge of tightening paperwork, shifting import levies, and more questions about long-term resistance management. We see more dialogue with customers now around stewardship, best practices, and education for prescribers—a field that is still evolving across continents.

    Our work does not finish at the factory door. Outreach to partners ensures responsible use, timely delivery, and safe handling up and down the supply chain. Our story, as direct manufacturers, can be traced from the initial blend of raw sulfanilamide to the hands of a pharmacist or veterinarian. Each lot reflects not just a code on a drum but an investment in ongoing technology, people, and environmental care.

    Supporting Facts from the Production Floor

    We keep strict batch control and full traceability on the shop floor, not just in the office. Drums of raw inputs pass across sensors, and every finished lot comes with records logged against our digital platform. We meet or exceed internationally recognized pharmacopoeias for Sulfisoxazole—years of audit data from outside agencies back that up.

    Every outbound shipment gets logged against an archive of test results—microbiology, solvent residue, heavy metals—available for partners with just a request. Our customers know they can ask for any historic sample, and we can retrieve retention samples marked for long-term compliance. These procedures have held up well in audits—customers say this keeps their own end-product compliance tight, especially under increasing regulation.

    Conclusion: A Continuous Commitment

    For those working at the sharp end of infection control, Sulfisoxazole made to reliable standards provides a dependable tool for patients, prescribers, and procurement officers. By respecting both the tradition and the ongoing demands around this product, we can keep trust intact from factory to field. Everything we’ve built into our Sulfisoxazole operation reflects not only decades of chemical knowledge but also the reality that the world’s need for solid, dependable antibiotics persists.