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Sulfaquinoxaline

    • Product Name Sulfaquinoxaline
    • Alias 6-quinoxaline sulfonamide
    • Einecs 204-609-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    332175

    Chemical Name Sulfaquinoxaline
    Cas Number 59-40-5
    Molecular Formula C14H12N4O2S
    Molecular Weight 300.34 g/mol
    Appearance White to yellowish crystalline powder
    Solubility Slightly soluble in water, soluble in alcohol
    Usage Antibacterial agent, mainly in veterinary medicine
    Mechanism Of Action Inhibits bacterial folic acid synthesis
    Therapeutic Class Sulfonamide antibiotic
    Common Administration Route Oral
    Target Species Cattle, poultry, swine
    Storage Conditions Store in a cool, dry place away from light
    Melting Point 196-200°C
    Brand Names Solquin, Quinoxalina, Sulfquinox
    Toxicity May cause hematuria and crystalluria at high doses

    As an accredited Sulfaquinoxaline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Sulfaquinoxaline is packaged in a sealed, labeled 500g HDPE bottle with hazard warnings, batch information, and storage instructions.
    Shipping Sulfaquinoxaline should be shipped in tightly sealed containers, protected from light, moisture, and physical damage. It must be clearly labeled, accompanied by relevant safety documentation (MSDS), and transported according to applicable regulations for chemicals. Avoid contact with incompatible substances. Handle with care, ensuring appropriate temperature and ventilation during transit.
    Storage Sulfaquinoxaline should be stored in a tightly closed container, in a cool, dry, and well-ventilated area, away from direct sunlight and sources of ignition. It should be kept away from incompatible substances such as strong oxidizers. The storage area should be secure and clearly labeled, with limited access for authorized personnel only. Store at room temperature, avoiding excessive heat and moisture.
    Application of Sulfaquinoxaline

    Applications of Sulfaquinoxaline in Industrial Manufacturing

    As a primary manufacturer of sulfaquinoxaline, we supply this compound to several specialized sectors within the animal health and feed additive industry. Each application follows specific production guidelines, quality control benchmarks, and regulatory requirements. Below we outline its industrial roles and the associated downstream processes.

    1. Veterinary Pharmaceutical Formulations for Livestock

    Veterinary drug producers use sulfaquinoxaline as an active ingredient in formulations targeting protozoal infections, especially coccidiosis in poultry and ruminants. Production lines integrate the raw material during wet granulation or blending, following compliance audits and ingredient verification. Formulation QC tests content uniformity and adherence to label claims. The end products undergo dissolution profiling and heavy metal screening prior to batch release.

    Industry compliance standards

    • China Veterinary Pharmacopoeia (latest edition)
    • European Pharmacopoeia (Ph. Eur. 10.0 or later)
    • U.S. FDA Good Manufacturing Practice (21 CFR Part 211)
    • VICH GL33 Residue Control Guidelines

    Typical usage ratio

    • Active loading: 2–5% in tablet or powder premix formulations
    • Dosing depends on livestock species, therapeutic protocol, and withdrawal times

    Downstream process integration

    • Blending into granulation or direct compression for oral tablets
    • Suspension pre-mix for oral solutions and drench formulations
    • Quality analysis in final QA/GLP stability studies

    Final product types

    • Oral tablets for chickens, turkeys, cattle, and goats
    • Soluble powders for poultry drinking water systems
    • Oral suspension and drench products

    2. Medicated Feed Additives for Intensive Animal Farming

    Animal feed integrators utilize sulfaquinoxaline at specified trace levels as a medicated additive to control intestinal coccidial outbreaks. The compound enters feed mixing via micro-dosing equipment, subject to HACCP and GMP+ assurance. Producers maintain documented process controls for traceability, ensuring analytic recovery after pelleting. Finished batches require residue analysis and certificate of analysis before distribution to farms.

    Industry compliance standards

    • EU Reg. 1831/2003 (Additives for use in animal nutrition)
    • China Feed Additive Quality Standard GB/T 1886.236
    • FSMA (Feed Safety Modernization Act, U.S. 21 CFR Part 589)
    • Codex Alimentarius Code of Practice on Good Animal Feeding (CAC/RCP 54-2004)

    Typical usage ratio

    • 100–250 g/T of complete feed, adjusted by weight of animal and target species
    • Dosing targets compliance with local Maximum Residue Limits (MRLs)

    Downstream process integration

    • Micro-component dry blending with carrier premixes before final feed pelleting
    • Thermal stability verified during extrusion or steam conditioning steps
    • Routine residue monitoring in finished feed for regulatory reporting

    Final product types

    • Complete pelleted feeds for broilers, layers, and turkeys
    • Concentrate premixes for on-site feed blending
    • Medicated mash and crumble feed formats

    3. Water-Soluble Veterinary Solutions Manufacturing

    Factories specializing in veterinary water medications formulate sulfaquinoxaline as an easily dispersible powder or solution concentrate. The production process requires high-purity API with controlled particle size distributions for solubility. Liquid and powder dosage forms receive final sterility assurance and preservative testing. Automated filling and packaging follow CIP/SIP sanitation cycles, meeting batch release and retention sampling policies.

    Industry compliance standards

    • WHO GMP guidelines for veterinary pharmaceuticals
    • Environmental Protection Law of China (for process effluent)
    • Local market MRL and withdrawal times as issued by agricultural authorities
    • IPEC-PQG GMP Guide for Pharmaceutical Excipients

    Typical usage ratio

    • 2–5% w/v for concentrate, diluted to 0.01–0.1% in farm water lines
    • Ratio depends on disease prevalence and farm management protocols

    Downstream process integration

    • Direct blending with solubilizing excipients under controlled pH
    • Sterile filtration prior to filling for liquid solutions
    • Automated sachet/bottle packaging for water dispersible powders

    Final product types

    • Drinking water medications for poultry and rabbits
    • Liquid concentrate veterinary drugs
    • Powder sachets for on-farm mixing

    4. API Supply for Contract Research and Reference Standards

    Certified analytical providers and contract research organizations procure sulfaquinoxaline as a reference material for purity testing, method development, and regulatory submissions. Suppliers provide validated purity and impurity profiles accompanied by COA and isotopic labeling when required. Test labs use these lots for LC-MS/MS method calibration, stability studies, and matrix recovery validations per GLP requirements.

    Industry compliance standards

    • ISO/IEC 17025 (Testing and calibration laboratories)
    • USP Reference Standards program
    • OECD Good Laboratory Practice (GLP) Principles
    • ICH Q7: Good Manufacturing Practice for APIs

    Typical usage ratio

    • 0.01–0.1% by weight for standard preparations and spike recovery tests
    • Batches subdivided based on test protocol and calibration requirements

    Downstream process integration

    • Preparation of calibration curves for residue analysis in animal tissues
    • Internal standard addition for feed and pharmaceutical quality tests
    • Accelerated stability testing and stress degradation studies

    Final product types

    • Certified reference standards
    • Research-use-only (RUO) analytical kits
    • Documentation for regulatory submissions and import clearance
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    Certification & Compliance
    More Introduction

    Sulfaquinoxaline: A Practical Perspective from Direct Manufacture

    Crafting Sulfaquinoxaline for Real-World Demands

    Sulfaquinoxaline has found a place in the veterinary sector, especially in animal husbandry. Having produced this compound for years, we’ve witnessed up close both the expectations of field veterinarians and the evolving concerns around livestock disease management. There’s a clear demand for products that deliver consistent results and minimize risk. Sulfaquinoxaline fills an important gap for many practitioners who deal with challenges like coccidiosis and bacterial enteritis in poultry and livestock.

    The difference between talking about solutions and shaping them at the chemical level runs deep. Our process walks the line between scientific rigor and on-the-ground realities. Each batch starts with carefully sourced raw materials, processed in facilities built for pharmaceutical-grade compounds. This hands-on approach allows us to oversee every reaction and ensure contaminant levels stay within acceptable limits. We invest in purification steps that go beyond minimum requirements, understanding that the final use doesn’t allow margin for dust, unknown residues, or fluctuating potency.

    Understanding the Model & Specifications

    Every product leaving our site carries the mark of the direct synthesis process. Purity is the benchmark that matters most, since practitioners rely on consistent dosing. Our technical teams operate advanced HPLC and UV spectrophotometers on every batch, consistently achieving material grades >99% by HPLC assay. The crystalline powder format allows for rapid dissolution — not a minor consideration in field conditions where water-medicating equipment can be unreliable. Color, particle size, and moisture content draw attention in each round of analysis, because even minor deviations can cause dosing errors or slow mixing times.

    Sulfaquinoxaline, as we produce it, comes in both raw active form and tailored admixtures for water-soluble and feed-grade applications. Over the years, requests from integrated farms led us to develop both fine and granular cuts, as well as custom blends to facilitate mixing with local feed types. Specifications always match the finished outcome, so we listen directly to veterinarians and adjust accordingly.

    Usage Experience in the Veterinary Field

    Many veterinarians seek out sulfaquinoxaline for its targeted action against coccidia and several forms of enteric bacteria. The compound’s absorption and excretion rates in livestock are well-documented, which gives farmers more certainty in withdrawal times and residue compliance. Our job goes beyond shipping finished powder; we consult with veterinarians as they address cases in the field. They describe livestock with poor appetites, loose stools, or sudden outbreaks that threaten entire flocks. The feedback we receive returns to our development process, ensuring formulations remain practical and safe even in stressful environments.

    No two farms are alike, so we’ve learned that flexibility matters. Some clients request custom-milled powders for automated dosing systems. Others seek blends compatible with nutrients or medicated premixes. In each scenario, we inherit part of the animal health chain: error in measurement or unexpected batch variability directly impacts animal well-being and, ultimately, profitability.

    Leaving the Lab: Life Cycle from Factory to Farm

    Handling the entire life cycle of sulfaquinoxaline — from initial synthesis to final formulation — places unique demands on our manufacturing process. Quality standards stem not only from regulatory requirements, but also from the tangible needs experienced by the buyers and end-users we meet. Packaging plays a larger role than often assumed: moisture ingress, static buildup, or improper seals bring real risk. Industrial foil linings and nitrogen flushing become as important as drying techniques in our processing rooms. Through repeated cycles, we’ve found the right combinations that hold up during long-distance shipping without clumping or contamination.

    Modern livestock operations call for reliability and traceability. By tracking each batch down to its raw material batch code, we provide clients with documentation that can withstand rigorous inspections. Not every market provides the same infrastructure or testing facilities, so our team takes up the burden of full-spectrum analysis for every major parameter. Our chemists keep records for impurity profiles, microbial counts, solubility rates, and chemical stability under typical farm storage conditions. This isn’t legal compliance for its own sake—its value shows itself in reduced product recalls and improved animal health outcomes at the ground level.

    Differences from Alternative Products

    Manufacturing sulfaquinoxaline brings constant comparison with other veterinary sulfonamides such as sulfadimidine, sulfamethazine, or the popular broad-spectrum combinations. We don’t just watch published efficacy tables; we see where other compounds fall short under real stress. Some competitors offer broad action spectrums but lose specificity, leading to a higher risk of resistance or unintentional impact on beneficial flora.

    Our product stands out due to its high level of selectivity for Eimeria species and a documented side effect profile developed through years of field feedback. We have seen, after consultation with both large and small-scale farms, that switching to sulfaquinoxaline often allows for reduced dosing frequency. Our quality control history shows fewer reports of crystalluria or nephrotoxicity compared to some older generics. That results from both the inherent chemistry and the rigor of purification maintained in our manufacturing.

    Water-solubility also marks a dividing line between products. Many feed-grade sulfonamides clump or fail to dissolve fully in hard water. Through direct adjustment of particle size and drying methods, we deliver a powder that disperses evenly—critical for flocks where uniform medication determines survival rates. We have found that smaller flocks often lack professional mixing equipment, leading us to trial and supply instantly dispersible grades for manual bucket mixing.

    Meeting Today’s Regulatory and Farm-Level Challenges

    Antimicrobial resistance ranks high among concerns, and manufacturers take responsibility seriously. Oversight doesn’t stop at the factory door. By producing sulfaquinoxaline in a tightly monitored environment, we reduce the risk of impurity-induced cross-reactivity and help users dose with greater certainty. This reduces the temptation for overuse or off-label administration. On the regulatory side, continuous communication ensures that specification sheets match current registration requirements in all served markets. We maintain dialogue with regulation agencies, updating certificates and technical dossiers whenever authorities revise MRLs or label restrictions.

    Feedback from the field often highlights overlooked issues—such as the stability of sulfaquinoxaline under tropical storage or its behavior when mixed with locally sourced feeds. Multiple temperature and humidity cycles can test packing integrity and product quality. Our solution involves shipping validation tests and “worst-case” storage simulations in our in-house stability chambers. These efforts reflect the reality that paper specifications matter little if the product in a remote warehouse no longer matches what left the plant.

    We’ve also supported research on the long-term residue profile in meat and eggs. Modern consumers demand proof of withdrawal periods and negligible residues, and veterinarians must follow through in practice. Our analytical teams invest in both routine confirmatory tests and independent lab collaborations, validating that our manufacturing and purification consistently deliver clean results. This commitment benefits producers facing strict export requirements.

    Driving Practical Solutions Forward

    Listening to users at every link of the chain, from pharmaceutical compounders to field veterinarians, shapes every change made in the factory. Our R&D group oversees not only production chemistry but tracks reports from the ground to refine future batches. We have responded to calls for smaller pack sizes, single-use sachets, and instructions written in multiple languages. Packaging changes grew out of seeing the real problems faced by farm workers preparing mixtures pre-dawn, often with little formal training.

    Some regions demanded products verified for both local and international residue standards, so we adjusted our testing protocols. We included screening for a broader spectrum of metabolites and split testing between local partner labs and our main plant. This approach builds trust and safeguards product acceptance at international borders or by third-party certification bodies.

    We believe the difference between a successful and problematic sulfaquinoxaline product boils down to traceability, communication, and willingness to step beyond the basics. If a farmer calls in reporting an unexpected reaction in a flock, our technical support tracks the batch number and initiates a full review of all records. We see ourselves not just as suppliers but as partners in the broader food chain.

    Looking Beyond Simple Bulk Supply

    Bulk chemical supply doesn’t fully capture the complexity of what direct manufacture involves. Each new production run draws on the experience and lessons from the last. Our investment in analytical technology grows, not from marketing ambitions, but from practical need. For example, as cross-contamination standards tightened worldwide, we invested in new washing protocols for reactors and downstream equipment. This keeps allergen risk negligible and ensures that every kilogram meets the declared specification with no cross-lot contamination. These tweaks and investments rarely appear on certificates but matter on-the-ground for every user downstream.

    Another shift over recent years came from the push for green chemistry and energy-efficient processing. We implemented solvent recycling units and optimized reaction temperatures to reduce the carbon footprint per batch. Alongside that, upgraded dust extraction systems and closed-loop drying cut down on worker exposure and environmental emissions.

    Shipping also brings unique complexity for veterinary actives. Several regions faced rising antibiotic regulation and import checks, making batch traceability, transparency in documentation, and up-front stability testing crucial. Our product managers routinely share analytical dossiers and impurity logs with regulators and large buyers to preempt issues that might interfere with import or use. These steps, embedded in the day-to-day running of our facility, create the reliability that customers recognize.

    Focus on Safety, Clarity, and Future Development

    A decade of direct production has underscored that even small lapses in manufacturing or documentation present risk. Label mix-ups, undetected impurities, or incomplete dissolution can ripple down the chain and harm not just animals but also those responsible for their care. We close the loop with training both in-house and for major buyers; when new farm hands prepare medicated water, they have clear visual guides and dosing charts that reflect real batch concentrations, not theoretical averages.

    Requests for more sustainable packaging led us to transition several bulk pack sizes to recyclable materials. By listening to both veterinarians and farm workers at the user end, we continue to broaden pictorial quick guides and safety reminders. These aren’t regulatory necessities, but tools that make a difference where the product gets used every day.

    We continue to collaborate with both universities and industry groups investigating alternatives for coccidiosis and multidrug-resistant infections. As regulatory climate shifts and global distribution channels evolve, we stay closely involved in both technical development and practical application. Field trials, feedback on administration routes, and new mixing technologies drive tweaks in production and distribution.

    Delivering More Than a Product: Commitment in Every Batch

    Direct manufacture means living with the consequences of every process decision. Choices about raw material sources, purification steps, and in-plant monitoring don’t stray into abstraction—they show up in the field outcomes veterinary professionals and farmers experience. The role of sulfaquinoxaline in disease management stays significant, not only because of its pharmacology but due to the demands of its real-world application. Being part of every stage—from chemistry to shipping to post-market support—shapes a stronger understanding of what clients actually need. It also helps us evolve more quickly as both science and industry move forward.

    Sulfaquinoxaline continues to find a firm role in the veterinarian’s toolkit, but that position never feels guaranteed. Constant adaptation, quality focus, and honest communication safeguard the product’s trustworthiness in a world full of shifting regulations and fast-moving animal health challenges. By remaining focused on tangible quality, traceability, and the practical needs at every step, direct manufacturers like us contribute more than the sum of raw material and paperwork—we help maintain the foundations on which both farm productivity and public trust rely.