Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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Sulfamide

    • Product Name Sulfamide
    • Alias Sulfonamide
    • Einecs 200-854-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    889904

    Chemical Name Sulfamide
    Chemical Formula H2NSO2NH2
    Molecular Weight 96.12 g/mol
    Appearance White crystalline solid
    Melting Point 205 °C
    Boiling Point Decomposes before boiling
    Solubility In Water Soluble
    Cas Number 7803-58-9
    Odor Odorless
    Ph Neutral in aqueous solution
    Density 1.57 g/cm3
    Synonyms Sulphamide, Sulfamic diamide
    Stability Stable under recommended storage conditions

    As an accredited Sulfamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White, high-density polyethylene bottle with screw cap, labeled "Sulfamide, 500g," hazard pictograms, safety instructions, and batch number.
    Shipping Sulfamide should be shipped in tightly sealed containers, protected from moisture and direct sunlight. It is non-hazardous but should be handled with standard precautions. Transport in accordance with local, national, and international regulations. Ensure proper labeling and documentation. Store and ship away from incompatible substances, particularly strong oxidizers or acids.
    Storage Sulfamide should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from moisture, heat, and incompatible substances such as strong acids and bases. Protect it from direct sunlight. Proper labeling and secure shelving are recommended to prevent spillage or accidental contact. Always follow relevant safety protocols and local regulations for chemical storage.
    Application of Sulfamide

    Applications of Sulfamide in Industrial Manufacturing

    Sulfamide is a specialty intermediate valued for its controlled reactivity and high purity, serving several defined sectors as an integral component in advanced chemical production chains. Our material supports stringent industrial requirements, allowing manufacturers to achieve precise formulation targets and process stability across multiple production scenarios. The sections below detail core downstream applications where sulfamide directly contributes to final product performance, compliance, and cost control in real-world manufacturing environments.

    1. Pharmaceutical Synthesis: Sulfonamide-Based Antibiotics

    Pharmaceutical companies incorporate sulfamide as a critical starting intermediate in the manufacture of sulfonamide antibiotics, contributing to the formation of key active pharmaceutical ingredients (APIs). Sulfamide’s incorporation influences reaction yields and purity profiles, making it indispensable for scalable batch and continuous-flow synthesis routes. Quality assurance teams rely on accurate dosing and impurity control to meet global pharmacopoeial standards during compound development and commercial API production.

    Industry compliance standards

    • USP (United States Pharmacopeia) methods for antibiotic APIs
    • ICH Q7A Good Manufacturing Practice (GMP) for APIs
    • EDQM CEP (European Directorate for the Quality of Medicines) for sulfonamides
    • Chinese Pharmacopoeia monographs for primary sulfonamide agents

    Typical usage ratio

    • 0.8–1.2 molar equivalents relative to target API backbone, adjusted to optimize yield and minimize side reactions based on substrate reactivity and process scale

    Downstream process integration

    • Direct inclusion in the acylation or amination step of sulfonamide API synthesis; added during controlled reactor charging under inert atmosphere and monitored for conversion by in-process analytical QC

    Final product types

    • Bulk sulfonamide pharmaceutical APIs (e.g., sulfamethoxazole, sulfadiazine)
    • Finished antibiotic dosage forms (tablets, suspensions) after downstream formulating and tableting

    2. Sweetener Manufacturing: Sodium Cyclamate Production

    Food ingredient manufacturers use sulfamide as the precursor in the synthesis of sodium cyclamate, a non-nutritive sweetener. The stepwise reaction pathway requires precise conversion and purification of sulfamide to guarantee both the safety and sweetness index of the final product. Facilities employ multi-stage quality monitoring to comply with international food safety and additive guidelines, with specific focus on residual contaminant thresholds.

    Industry compliance standards

    • FAO/WHO Codex Alimentarius General Standard for Food Additives (GSFA)
    • GB 2760 (China National Food Safety Standard for Use of Food Additives)
    • FDA 21 CFR 172.130 for sodium cyclamate use
    • ISO 22000 food safety management system during sweetener production

    Typical usage ratio

    • Equimolar dosing with cyclohexyl chloride in the initial sulfonation stage; typical batch processes range from 1.0–1.1:1 molar ratio, refined to target complete conversion and minimize unreacted sulfamide

    Downstream process integration

    • Charged into the cyclohexylamine sulfonation reactor post-pH adjustment; involved in subsequent neutralization and crystallization process steps to produce food-grade sodium cyclamate

    Final product types

    • High-purity sodium cyclamate crystals
    • Liquid sweetener concentrates and table-top sweetener products
    • Formulated beverage sweetening premixes

    3. Plastic Additives: Flame Retardant Systems for Polyamide Materials

    Sulfamide functions as an effective flame retardant additive or intermediate in polyamide plastic compounding operations, where it imparts improved fire resistance and thermal stability to molded industrial parts. Engineering plastics manufacturers directly introduce the material in defined masterbatch formulations, with strict validation to ensure consistency in mechanical and combustion performance. Regulatory compliance for flame retardant systems is critical, given end-use in automotive and electronics sectors.

    Industry compliance standards

    • UL 94 Flammability Testing (Underwriters Laboratories)
    • RoHS Directive (2011/65/EU) for hazardous substance limits
    • IEC 60695-2-11 Glow-wire Testing for thermal stress
    • REACH (EC 1907/2006) registration and SVHC status

    Typical usage ratio

    • 0.5–3.0 wt% based on polymer mass; dosage calibrated according to flame retardancy class (V-0, V-1), matrix resin type, end-product thickness, and synergistic effect with other retardants

    Downstream process integration

    • Blended into the polymer melt during extrusion or compounding; integrated into masterbatches or direct-mold formulations prior to pelletizing and further thermoplastic processing

    Final product types

    • Polyamide compound granules for injection molding
    • Electrical component housings and connectors
    • Automotive structural and interior parts with certified fire performance

    4. Textile Finishing: Antichlor Treatment in Bleached Fabrics

    Industrial textile finishing facilities leverage sulfamide as an efficient antichlor agent to eliminate residual chlorine after fabric bleaching. The process reduces fabric yellowing and improves final dyeing uniformity, meeting customer and regulatory standards for both domestic and export-grade textiles. Process engineers set dosing based on in-line chlorine detection and fabric throughput, enabling cost-effective and sustainable water management.

    Industry compliance standards

    • OEKO-TEX Standard 100 for chemical residues
    • ZDHC Manufacturing Restricted Substances List (MRSL)
    • REACH (EC 1907/2006) for textile auxiliaries
    • AATCC Test Method 94 for antichlor effectiveness

    Typical usage ratio

    • 0.1–0.5 g/L in final wash—concentration set via chlorine titration results, with adjustments for equipment type, fabric grammage, and residual chlorine load following batch bleaching

    Downstream process integration

    • Dosed into the last rinse bath post-bleaching; followed by short agitation and drain; engineers monitor residual chlorine on-fabric before releasing for dyeing or further finishing

    Final product types

    • Cotton and synthetic blended fabric rolls
    • Pretreated textile substrates for garment manufacturing
    • Eco-compliant home textiles for export and domestic retail

    5. Electroplating: Brightener Component for Nickel Baths

    Specialty electroplating shops select sulfamide as a controlled-brightener agent in nickel-plating bath formulations to enhance deposit uniformity and sheen on metal components. The compound enables stable plating characteristics and supports compliance with surface finish standards in EU and US markets, particularly for applications in decorative hardware and electronic connector production. Process engineers tailor the addition rates to tank volume and desired surface finish.

    Industry compliance standards

    • ASTM B689 for electroplated nickel coatings
    • ISO 1456 for decorative and protective nickel plating
    • RoHS Directive (2011/65/EU) for electrical hardware coatings
    • ISO 9001-certified process controls for plating operations

    Typical usage ratio

    • 10–50 mg/L in total bath volume; optimized per tank maintenance cycle, workpiece geometry, and desired deposit properties (mirror sheen, hardness)

    Downstream process integration

    • Added to the nickel sulfate-based bath during the make-up or replenishment stage; monitored by bath analytics and replenished based on plating throughput and test panel assessments

    Final product types

    • Precision metal fittings with decorative nickel finishes
    • Electrical connectors and terminals
    • Automotive and appliance hardware components
    Free Quote

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    Certification & Compliance
    More Introduction

    Sulfamide: Leveraging Precision in Chemical Manufacturing

    Direct Insight Into Sulfamide Production and Applications

    Our team has spent decades working hands-on with sulfamide, and we know every step of its production, from the reaction vessel to the final packaging. Sulfamide itself links the simple with the versatile; this compound carries unique chemical characteristics that make it useful for both industry and research. Casually known to chemists as H2NSO2NH2, it shows up time and again as a reliable intermediate and end-product.

    Every batch that leaves our plant comes from the real chemistry done on the ground—but not every manufacturer applies rigor at each stage. Small changes in reaction pH or feedstock impurities can shift the quality curve, making control, transparency, and an experienced eye for detail essential. Years of process development have let us dial in the optimal method. Our sulfamide model—produced through controlled reaction between sulfuryl chloride and ammonia—puts consistency and purity first. Typical lots contain minor traces of inorganic salts, but regular monitoring ensures they remain below the critical threshold. Our standard product meets technical grade requirements, and we offer a reagent-grade variant for analytical laboratories where purity is paramount. We built these specifications not from market trends, but from conversations with chemists and customers—people who judge quality by real-world performance, not just numbers on a certificate.

    A common question we hear is how sulfamide stands apart from more familiar sulfonamides or sulfur-based intermediates. The answer usually comes back to its balanced reactivity. Sulfamide’s stability means it survives storage, but under the right conditions it acts as a nucleophile or crosslinker in organic synthesis. Water solubility is moderate, so it dissolves quickly in warm water but can precipitate in colder conditions. Many plants overlook this and send out product with inconsistent moisture content or inconsistent particle sizing. We learned early that uniform milling and immediate drying keep the product usable, bag after bag. Waste is expensive, so nothing leaves the factory floor unless it flows smoothly and resists caking. That is one difference you’ll notice from a manufacturing source who understands actual plant operations.

    Supporting Applications With Practical Know-How

    We regularly consult with clients who use sulfamide in a range of settings. Water treatment professionals value it as a precursor in synthesis of specialty polymers aimed at treating municipal and industrial effluents. Paint additive producers rely on its mild reducing action in corrosion inhibitor blends. Even agricultural chemistry taps into sulfamide when building novel plant protection agents. Despite its technical applications, the rules of handling and process safety don’t change—it pays to know its reactivity profile and potential for off-gassing under acid catalysis.

    Working with resin chemists, we often connect over the reliable way sulfamide bridges monomers without excessive crosslinking. Research groups looking to make proprietary sulfonamide-based drugs find our highest spec material a dependable starting point—the low heavy metals content avoids side reactions, and particle sizing speeds up mixing. The food and beverage sector, bound by strict purity requirements, requests only trace levels of aromatic impurities. That means attention to cleaning protocols between production runs—an extra step for cost-cutters, but one that matters in downstream use.

    Finishing a synthesis only tells half the story. Stability in long-term storage often determines if a lot survives the supply chain. Our packaging room double-seals each bag in moisture-barrier film, pressing air out and monitoring weight fluctuations over time. We store finished sulfamide drums in temperature-controlled warehouses, and data loggers monitor both humidity and temperature, since shifts can lead to product hardening or clumping. Not everyone tracks lots after shipping, but recurring customer audits have trained us to keep complete records, lot-by-lot, all the way back to raw materials. This depth of traceability isn’t marketing—it's part of keeping doors open year after year.

    Differences That Matter: Sulfamide Versus Other Compounds

    Comparing sulfamide to generic ammonium sulfamate or sulfanilamide quickly shows where it comes out ahead. Ammonium sulfamate delivers strong herbicidal action, but its decomposition profile makes it unsuitable where downstream amines cause issues. Sulfanilamide, by contrast, finds fame in antibiotic chemistry, but is less stable in high-pH environments. Sulfamide sits in the useful middle ground: robust under neutral or mild alkaline conditions, yet reactive enough for synthesis in the right solvent. Solubility in water and lower alcohols helps chemists build multi-functional derivatives, tuning downstream molecules for detergency, catalysis, or drug activity.

    Industrial designers sometimes default to more ubiquitous reagents based on price models. We urge direct conversation about what each compound must accomplish. Our experience shows sulfamide delivers value in processes requiring mild nucleophilicity and low by-product formation. Actual lab tests consistently back this up—sidestream analytics always show cleaner profiles and fewer reprocessing steps. Clients running continuous operations particularly appreciate the way our sulfamide resists degradation under heat or mild acid exposure, major advantages in large-scale flow systems. Technical teams often come to us after failures with generics or recycled by-product—after they’ve counted the cost of downtime and cleaning. Reliable, single-source material with a clear, factual certificate removes most of these headaches.

    Confronting Practical Problems in Production

    Scale brings complexity. We see smaller manufacturers struggle with batch-to-batch inconsistency, largely because sulfamide needs careful chlorination and neutralization. Exothermic reactions, if not cooled at just the right point, can skew purity, create insoluble tars, or spike residual chloride. We built custom reaction control systems based on hard-earned lessons, maintaining clear baselines for temperature and flow. Manual sampling and titration remain part of our quality protocol—not everything should be left to sensors. We still believe in skilled technicians inspecting each batch with their own eyes. This approach keeps us grounded, and our clients benefit from straightforward, no-surprise products.

    Impurities don’t just disappear in downstream use. One misstep in our own plant can multiply problems during a customer’s process. Whether it’s an unexpected yellow tint or odd odor, we track and troubleshoot at the source. Our logs and root-cause analysis provide more than paperwork—they drive continuous improvement. It isn’t enough to hit a spec sheet target: performance in the client’s application is the real proof. We keep communication honest, welcome feedback, and are willing to reformulate whenever repeat issues surface.

    We invest in staff training not as a compliance tick-box, but as a means to keep mistakes rare. Operators handle hazardous intermediates daily, and procedure drift can cost big. Regular audits and retraining sessions reinforce best practices, especially in transfer and neutralization steps. Our plant’s age demands this focus—no shortcut replaces real, lived experience. Instead of chasing clever, cheap fixes, we focus on robust process design, backed by staff who know why details matter. Our goal is to build trust batch after batch—a claim only a direct manufacturer, with faces behind the product, can stake authentically.

    Meeting Regulatory Demands With Practical Action

    Sulfamide is subject to chemical regulations—REACH in Europe, TSCA in the United States, and local rules elsewhere. These aren’t “box-ticking” exercises for us. Auditors arrive unannounced, ask tough questions, and demand real documentation. We track every incoming raw material, reconcile it to output, and manage waste accordingly. The rules shift, and it falls to us to adapt while keeping supply stable. New European standards on trace metals and persistent organics pushed us to revisit old process steps, and product adjustments followed. In North America, downstream users called for tighter particle control and new packaging compliance. These weren’t optional moves if we wanted our product to keep moving legally across borders.

    Clients trust us because our regulatory team understands the impact of these rules on both sides of the transaction. SDS documents aren’t filled out by generic software. Our team knows the hazards and quirks from years in the plant. We advise on handling, storage, and disposal—not simply because the law tells us, but because we want clients up to speed and safe. Real incidents, not just text, shape our thinking. Explaining risk plainly and offering tailored advice makes us partners, not just suppliers. That approach brings repeat business and deep professional respect from old-school and new-generation buyers alike.

    Improving Sustainability and Resource Efficiency

    Chemical manufacturing faces constant pressure to reduce resource use and waste. We took a hard look at our sulfamide process years ago and cut solvent recycling losses, rerouted cooling water, and installed inline monitoring for effluent. Energy costs bite most in drying and milling, so we fine-tuned the process to minimize storms of dust or energy-guzzling second passes. Our plant releases treated water that meets discharge permits—no shortcuts or dilution tricks. Staff often spot problems faster than monitors, making human vigilance indispensable. Recycling packaging materials led to minor savings at first, but over the longer haul, waste and landfill costs dropped, which justified redesigning our drums and sacks.

    Large-scale changes take time and resources, but small, regular adjustments keep the factory competitive. We partner with waste handlers to ensure spent reactants don’t make their way into local landfills, and our records document every outbound shipment. Auditors and industry peers know which plants cut corners. Our goal is to earn respect inside and beyond the fence line, showing that good stewardship and robust management go hand in hand. The trust we build with neighbors and regulators is not just a side effect of producing sulfamide; it’s an everyday commitment.

    Facing the Supply Chain Reality

    Supply chain disruptions ripple through every factory. Windstorms, raw material shortages, or shipping lags—these aren’t abstract risks. We weather them with deliberate inventory planning and longstanding relationships with key suppliers. In a world where delay costs jobs and impacts customer operations, our direct link to reactors, not to a middleman, becomes critical. Direct oversight lets us flex production or adjust specifications if a critical raw material runs short, always communicating ahead so nobody is left guessing.

    Risk doesn’t disappear just because processes run smoothly on most days. That’s why we built backup storage for both finished product and critical inputs. Close ties to upstream sources let us secure allocation during market spikes, and years of trust go into those handshake deals. Our experienced operators can adjust recipes on the fly—without sacrificing product performance. Transparent logistics tracking and access to batch records provide answers immediately, not after a lengthy investigation. Third parties try to mimic this level of service, but only a true manufacturer can guarantee it at the scale and frequency real-world markets demand.

    Customer Relationships Built on Authentic Experience

    Clients often ask more from us than just a drum of chemical. They need troubleshooting, product validation, and genuine partnership when things don’t go as planned. Our staff, many with a decade or more on the job, speak frankly about what sulfamide can do—and what it can’t. We urge customers to share their actual issues, and we feed those back into development or process improvements, not simply to lock in contracts. That open-door, steady-hand approach forges loyalty beyond price points.

    We recognize the temptation to chase lower-priced, off-spec, or grey-market material. Past experience has shown that the cheapest route often brings the most expensive lessons—reactor fouling, slow dissolutions, failed analytical tests. Each time, we absorb those lessons and double down on quality. Engineers and purchasing managers come back not for salesmanship, but for direct solutions and honest communication. We know the true cost of downtime, waste, and reprocessing, and our clients do, too.

    Every feedback loop makes us stronger. We keep logs of customer inquiries and field test results and invest in plant upgrades when patterns emerge. With sulfamide, as with any specialty intermediate, being the source gives us authority, but also responsibility. We meet that challenge head on, batch after batch, through candid exchange, a keen eye for details, and commitment to improvement that doesn't rest on slogans or stock phrases. We measure success not just by volumes sold, but by relationships squared away, crises resolved, and the steady reliability that repeats year after year.

    Summary of What Sets Our Sulfamide Apart

    Sulfamide occupies an important place in dozens of chemical value chains. Our approach to manufacturing isn’t about racing to the bottom but about building a foundation on knowledge, skill, and transparency. We designed and refined processes out of face-to-face conversations with technical users, not formulaic specs or catalog entries. That gives our product a clear edge in performance and reliability, something we stand behind.

    Our work over the years has shown us that every drum, every lot code, and every question from the end user matters. We believe that quality springs from well-maintained equipment, trained staff, and unbroken records, not just quarterly checklists. With sulfamide as with every specialty chemical we craft, we see the molecule as a bridge—from science to industry, from our plant floor to yours, ensuring each step brings readiness and peace of mind. If you’re working through a technical challenge or refining an application, our door is never closed. Expert voices, hard-won experience, and real commitment form the backbone of our offer. Every batch carries that legacy, and every future project benefits from it.