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Sodium Phosphate Monobasic Monohydrate

    • Product Name Sodium Phosphate Monobasic Monohydrate
    • Alias Monosodium Phosphate Monohydrate
    • Einecs 231-449-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
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    Specifications

    HS Code

    694679

    Chemical Name Sodium Phosphate Monobasic Monohydrate
    Chemical Formula NaH2PO4·H2O
    Molecular Weight 137.99 g/mol
    Appearance White crystalline powder
    Solubility In Water Easily soluble
    Ph Of 1 Percent Solution 4.1 to 4.5
    Melting Point 60 °C (dehydrates)
    Cas Number 10049-21-5
    Storage Temperature Room temperature
    Synonyms Monosodium dihydrogen phosphate monohydrate
    Odor Odorless
    Density 2.04 g/cm³

    As an accredited Sodium Phosphate Monobasic Monohydrate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White, sealed HDPE bottle labeled “Sodium Phosphate Monobasic Monohydrate, 500g,” with hazard symbols, batch number, and storage instructions.
    Shipping Sodium Phosphate Monobasic Monohydrate should be shipped in tightly sealed containers, clearly labeled, and protected from moisture. Store and transport in a cool, dry place. Follow all applicable local, state, and international regulations for safe handling and transport. Avoid contact with incompatible materials and ensure compliance with hazard communication standards.
    Storage **Sodium Phosphate Monobasic Monohydrate** should be stored in a tightly closed container in a cool, dry, and well-ventilated area. Keep it away from moisture, acids, and incompatible substances. Avoid exposure to excessive heat. Ensure storage areas are clearly labeled, and observe all standard laboratory safety protocols to prevent contamination or accidental contact.
    Application of Sodium Phosphate Monobasic Monohydrate

    Applications of Sodium Phosphate Monobasic Monohydrate in Industrial Manufacturing

    Sodium Phosphate Monobasic Monohydrate supports multiple industrial sectors through its properties as a buffering agent, pH adjuster, and dispersant. Its controlled purity and solubility allow for consistent integration into downstream production, contributing to the manufacturing of high-quality end products. Below, we detail major industrial application fields, technical integration approaches, and regulatory frameworks drawn from real industry practice.

    1. Food Additive Processing

    Food manufacturers incorporate this material as a leavening acid, emulsifier, and buffer in various processed foods. It helps manage pH in dairy blends, processed cheeses, powdered drinks, and cured meats. Production sites maintain strict separation of food-grade supplies, and all system flushing must use deionized water to prevent contamination. Dosing depends on target food systems, with continuous batch monitoring and rapid adjustment protocols in place to ensure food safety regulations compliance. The integration point is typically upstream in water-based slurries or as a dry blend, ensuring direct participation in ingredient hydration or chemical leavening reactions.

    Industry compliance standards

    • Codex Alimentarius INS 339(i)
    • US FDA 21 CFR 182.1778 (Generally Recognized as Safe - GRAS)
    • EU Regulation (EC) No 1333/2008 (E339(i) listing)
    • GB 2760-2014 - China Food Safety National Standards for Food Additives

    Typical usage ratio

    • 0.1% to 2.5% depending on matrix and local food laws; lower in beverages (0.05%-0.2%), higher in processed cheese (1.5%-2.5%)

    Downstream process integration

    • Added to brines, processed cheese slurries, bakery premixes, and direct in-line dosage for instant beverage blending

    Final product types

    • Processed cheese blocks and slices
    • Baking powders and self-raising flours
    • Powdered instant drinks
    • Cured or canned meat products

    2. Pharmaceutical Formulation Manufacturing

    Pharmaceutical plants use this material as an auxiliary buffering and dispersing agent within oral, parenteral, and ophthalmic formulations. Material enters at the solution preparation step for injection or in the powder blending phase for tablets and capsules. Quantitative adjustment aligns with target pH and osmolarity parameters, subject to process validation. Strict traceability and cross-validation across production batches guarantee that processing conditions meet the requirements for pharmaceutical GMP and global pharmacopoeia standards.

    Industry compliance standards

    • USP-NF Monograph: Monobasic Sodium Phosphate Monohydrate
    • Ph.Eur. (European Pharmacopoeia)
    • JP (Japanese Pharmacopoeia)
    • ICH Q7: Good Manufacturing Practice for Active Pharmaceutical Ingredients

    Typical usage ratio

    • 0.2% to 1.8% in tablets and oral solutions; injection uses optimized at 0.1% to 0.6% for isotonic adjustment

    Downstream process integration

    • Blending in granulation step for solid dosage, or dissolution into purified water for injectable/eye drop solutions

    Final product types

    • Buffered oral liquid syrups
    • Eye drop formulations
    • Injectable buffer solutions
    • Effervescent tablets

    3. Water Treatment Chemicals Manufacturing

    Manufacturers of water treatment chemicals apply this material as a blend component for corrosion inhibition, scale prevention, and pH management. Dosing accuracy and blend stability are controlled via automated batch or continuous mixing systems. The product enters at the formulation or homogenization stage and must meet chemical industry technical grade standards. Downstream, operators track dosage and water chemistry according to customer application quality audits and local water safety standards.

    Industry compliance standards

    • ANSI/AWWA B504: Sodium Phosphate for Water Treatment
    • NSF/ANSI/CAN 60: Drinking Water Treatment Chemicals—Health Effects
    • EN 1212: Chemicals used for treatment of water intended for human consumption

    Typical usage ratio

    • Blend component at 1% to 8% in finished corrosion inhibitor and scale control products; end use dosing: 1.5–10 mg/L in process water

    Downstream process integration

    • Enters at blending, pre-mix, or dilution phase for liquid concentrate and powder formulations

    Final product types

    • Municipal drinking water treatment solutions
    • Industrial boiler water conditioning blends
    • Cooling tower scale inhibitors
    • Closed circuit corrosion inhibitors

    4. Detergent and Cleaning Product Manufacturing

    Within the detergents sector, manufacturers insert the material primarily in automatic dishwasher powders, institutional cleaners, and certain specialty industrial cleaning agents. Its hydrotropic and buffering properties support steady solubilization of other actives. Entering at the bulk blending/mixing step or as part of an agglomerated granule, it provides process benefits by controlling solution pH and assisting dispersal of fats and inorganic ions. Plant process teams verify concentrations by in-process QC sampling aligned to formulation sheets, with fully documented batch traceability to downstream B2B customers.

    Industry compliance standards

    • EU Detergent Regulation (EC) No 648/2004
    • US EPA Safer Choice Program (relevant for ‘green’ cleaning blends)
    • GB/T 13174 – Industrial Detergent Specifications (China)

    Typical usage ratio

    • Typically 5–18% in dishwasher powders; 2–10% for institutional and industrial cleaner base blends

    Downstream process integration

    • Bulk blending into powder mixes, pre-dissolution for liquid detergents, or direct dosing into agglomeration for tabletized products

    Final product types

    • Automatic dishwasher powders and tablets
    • Laundry pre-soak agents
    • Industrial floor and equipment cleaners
    • Institutional kitchen detergents

    5. Catalyst and Surface Treatment Preparation

    Surface engineering and catalyst manufacturers use this phosphate as a raw material in metal treatment, electroless plating baths, and as a precursor for supported catalysts. SOP monohydrate is integral as a control agent for pH and as a phosphate source promoting even layer deposition. Supply enters at the bath preparation stage, where procedural controls maintain precise solution chemistry. Custom formulations target downstream applications specified by OEM surface engineers, and properties undergo batch qualification prior to delivery.

    Industry compliance standards

    • ASTM B607 – Electroless Nickel-Phosphorus Coatings Specification
    • ISO 4527 – Electroless nickel-phosphorus alloy coatings
    • REACh Regulation (EC) No 1907/2006 (Registration in chemical surface treatment protocols)

    Typical usage ratio

    • 5–20 g/L in electroless plating baths; 2–10% in slurry/catalyst precursor blends

    Downstream process integration

    • Incorporation into plating bath compositions, slurry formulations for catalyst supports, or pre-treatment solutions for metal finishing

    Final product types

    • Electroless nickel coatings
    • Ceramic-supported Ni or Pt catalysts
    • Phosphated steel sheets
    • Pre-coated industrial fasteners

    6. Laboratory Reagents and Diagnostics Production

    Diagnostic kit and analytical reagent producers select this phosphate for buffer formulation and as an ionic strength adjuster in test strips, blood chemistry reagents, and standard solutions. The material enters at the buffer preparation and final blending steps, with batch records referencing analytical or molecular biology grade standards. Dosage adapts to target analyte and desired pH stability, with full batch verification against method performance parameters set by QC laboratories.

    Industry compliance standards

    • ISO 9001:2015 (quality management for reagents)
    • EN ISO 13485:2016 for production of medical devices/in vitro diagnostics
    • CLSI (Clinical and Laboratory Standards Institute) procedures for clinical laboratory reagents

    Typical usage ratio

    • 0.1–1.5% in buffer solutions; ranges depend on diagnostic matrix and specific protocol requirements

    Downstream process integration

    • Dissolution in buffer concentrates or direct addition to dry reagent and strip blends

    Final product types

    • Clinical chemistry reagent kits
    • Immunoassay and molecular diagnostic buffers
    • Blood gas analysis packs
    • pH standard solutions for laboratory reference
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    Certification & Compliance
    More Introduction

    Sodium Phosphate Monobasic Monohydrate: A Foundation in Industry and Science

    What Sets Our Sodium Phosphate Monobasic Monohydrate Apart

    As a chemical manufacturer, we have seen the role of Sodium Phosphate Monobasic Monohydrate (NaH2PO4·H2O, CAS 10049-21-5) shape applications in laboratories, food processing, water treatment, and industrial formulations year after year. Through decades of process refinement, the quality standard we deliver has always centered around consistency, purity, and reliability—a combination we’ve found matters more than anything for operations that cannot afford hiccups.

    Our monohydrate product comes in a range of mesh sizes to meet customer feedback gathered from the floor, where we hear that quick solubility and a dust-minimal flow make daily handling smoother. The chemical's form, white crystalline solid, reflects a careful manufacturing practice that starts from precise raw material controls and follows through with filtration and drying stages under calibrated conditions. Like most phosphate salts, the details in each batch draw from hands-on vigilance and a culture of in-process accountability we’ve built over time.

    Customers approach us looking for answers about differences among various phosphates. Sodium Phosphate Monobasic Monohydrate stands out from its di- and tri-basic relatives by the number of sodium ions and hydrogen atoms attached to the phosphate group. This apparently simple detail translates into real differences in pH adjustment, buffering range, and flavor impact, especially in food and biotech sectors. Monobasic versions meet the needs of acidifying buffers with better precision, helping maintain product stability and reactions where every decimal point matters.

    How Model and Specifications Guide Performance

    From the first years of producing sodium phosphate, we noticed two customers never wanted the product "just as is." They wanted assurances about exact assay levels and water content. Over time, we directed our engineering to target monohydrate grades with a typical NaH2PO4 content around 98% minimum along with a proper moisture range, minimizing variability in downstream recipes and batch records. Experience shows that even a one-percent deviation in assay impacts blending, so we started batch-by-batch industry audits to keep tight control over specification drift.

    Purity also plays a critical role in sensitive uses—pharmaceuticals, biotechnology, and electronics have zero room for heavy metal residues or unknown ions. To that end, we introduced double-filtration steps and closely watched thermal curves during production. Sulfate and chloride checks have come to be a mainstay in our in-house analysis, given occasional feedback from high-spec lab settings struggling with contamination. Over the years, lean manufacturing tools have proved most effective in error tracking and corrective actions, so each model’s batch records remain transparent and easily auditable throughout the chain.

    We produce sodium phosphate monobasic monohydrate in granular and fine powder forms to meet performance requests. Some customers need coarser particles for faster drainage in granulation, others prefer powders for rapid dissolution. Our equipment can switch mesh size with precision, and we keep regular open channels with users for feedback, leading to each production run reflecting market needs as they change.

    Key Differences Versus Dibasic and Tribasic Salts

    Many users ask for guidance between monobasic, dibasic, and tribasic forms. Based on experience with all three, the core difference shows up during application. Sodium phosphate monobasic monohydrate reacts more acidically in water, yielding a pH around 4.5, which fits well for buffer preparation in biochemical assays and medication suspensions. If the goal is to swing the pH higher or create basic buffer systems, sodium phosphate dibasic or tribasic steps in with less acidity.

    The choice matters for product taste and stability. In food applications, for instance, monobasic salt introduces a more pronounced tartness compared to the neutral effect of dibasic. Cheese processors we work with appreciate the fine line this facilitates in texture modification and flavor, leading to stable melting and consistent taste in spreads and sauces.

    In water treatment or metal processing, the monobasic form acts as a safe and effective sequestrant, preventing scaling and softening the impact of other dissolved ions. It does not form insoluble complexes with most water-borne metals except when pushed beyond recommended concentration—an operational 'safe zone' we often clarify with plant managers seeking maintenance-free pipelines.

    Experience Matters in Consistency and Safety

    Problems rarely come from the powder itself. They trickle down from a lack of transparency about what’s in the bag. Through decades of production, we have cut back on ambiguity by engaging with buyers at every stage and focusing on direct shipment from our site. Freshness counts—our teams keep lead times minimal and storage protected from moisture ingress, including dehumidified silos and anti-caking protocols on every pallet.

    Early years showed us how easily even well-sealed sodium phosphate monobasic monohydrate picks up water if left exposed. That can throw off measurements and flow rates in automatic feeders, so we emphasize batch dating and moisture-proof packaging for every run. If a client tests a caked sample, our records and policies let us quickly track lot codes and environmental controls down the chain, closing the loop for quality and customer trust.

    Personnel training rounds out the safety story. We make it a point to review safe handling of phosphates with our teams and always keep thorough up-to-date documentation on physical and chemical hazards. Regular drills and easy access to PPE make the difference for both bulk handlers and end-users. The real world rarely matches a textbook description, so we build safety thinking into both our process floor and our communication with partners.

    Why Quality Assurance Holds Value Beyond Compliance

    Chemical supply has never just been about filling an order. For sodium phosphate monobasic monohydrate, tracking trace metal levels and purity markers signals more than a checkbox on a compliance form—it spells out the difference between a reliable outcome and process failure. We have invested in in-house ICP-OES and ion chromatography units, an approach born from problems customers approached us with over the years. Frequently, high-purity sodium phosphate forms the backbone of nutritional additive blends and injectables, and even the faintest trace of iron, lead, or arsenic will bring an entire batch under scrutiny.

    We set up multi-point lab checks during process runs to catch inconsistencies, with calibrated equipment and validation schedules that reach beyond local requirements. Sticking to this line has helped us avoid recalls, failed test results, or, worse, interruptions to essential production in sectors such as dialysis solutions.

    Physical integrity also sits front and center. Our mill and granulation process includes stepwise sieving and vacuum transfers designed to minimize both dust and potential contamination. Packaging uses food-contact grade liners and multi-film barriers, which grew out of feedback from logistics partners highlighting long shipping times and climate variability during transit. Each such improvement responds to direct feedback from operators, not just abstract policy.

    Supporting Modern Applications in Industry

    Our sodium phosphate monobasic monohydrate feeds a range of industrial processes, including ceramics, dye production, waterborne adhesives, and cleaning product formulations. Manufacturers return for repeat orders tied to our record on batch consistency and supply chain reliability. Over the years, we have learned that production delays often cascade across entire plants, especially where sodium phosphate serves as a pH buffer or dispersant.

    In ceramics and refractories, it performs as a binder and deflocculant that offers better suspension of solids. Feedback from plant-floor technicians drove us to optimize solubility and flow, limiting lump formation in mixing tanks—one of the main causes of production loss in high-volume operations. Our clients in cleaning supplies rely on the mild acidity and the sequestrant properties, using monobasic sodium phosphate to control scaling and residue.

    The growing need for greener processes also touches our approach. In water treatment, customers showed us that phosphate-based formulations can address scale and heavy metal removal without aggressive acids or chelating agents that pose downstream risks. We work with municipal water operators and industrial plants to fine-tune dosages and supply pure product that delivers consistent outcomes, batch after batch.

    Food and Beverage: Real Insights from Processors

    Food industry partners look for quality and documentation, but practical concerns around solubility, acid taste, and regulatory approval often carry the most weight. Cheese and processed meat plants use monobasic sodium phosphate for flavor balance, pH control, and water retention. The fine distinctions among phosphate salts shape mouthfeel and shelf life, as more acidic products can produce both better textures and sharper flavor notes.

    Large-scale bakeries and beverage producers introduced us to problems of dusting, uneven dissolution, and caking. Through plant visits and batch tracking, we developed anti-caking tweaks and improved mesh gradation. Over the past decade, customer focus groups nudged us to upgrade our facility for food-grade production, validating with third-party labs to confirm compliance with evolving regulatory requirements. Feedback also led to lot-specific declarations on allergen absence, gluten content, and batch-based heavy metal screening.

    Requests for documentation remain strong. To respond, we keep all test records and batch release reports transparent, along with declarations for BSE/TSE, food irradiation, and nanomaterial content. This documentation informs procurement teams during audits and helps R&D groups push their products through regulatory hurdles. Our process improvement comes from listening closely to these evolving needs.

    Pharmaceutical and Diagnostic Buffer Preparation

    Pharmaceutical clients draw clear lines around quality and documentation requirements for sodium phosphate monobasic monohydrate. From vaccine production to dialysis fluids, every shipment falls under exacting scrutiny for purity, residual moisture, and trace contaminants. Over the years, these demands led us to install closed-system drying and blending. Reports are batch-specific, with each bag traceable to raw materials and in-process controls.

    In buffer systems, monobasic sodium phosphate blends with dibasic forms to produce desired pH ranges. Technicians on the ground appreciate having reliable, rapid-dissolving material—especially in bioprocessing setups where scale and time-to-dissolve translate into real cost. By working alongside customer R&D, we have fine-tuned mesh gradation and water-of-crystallization controls, so every container offers the same behavior, streamlining large-scale batch prep for injectable and diagnostic applications.

    Product recalls or regulatory notices prompt immediate supplier questioning, so we back every batch with a full certificate of analysis and decade-spanning retention of traceability records. Ongoing technical support covers common challenges in buffer prep, caking control, and residue minimization, with input from both lab technicians and production floor staff.

    Environmental and Water Treatment Impacts

    Sodium phosphate monobasic monohydrate plays a role in modern water treatment across cities, food plants, and industrial users. It controls undesirable metal ions, softens hard water, and stabilizes system pH in municipal plants. Our field teams have spent time on-site at water utilities, troubleshooting everything from scale deposition in pipes to foaming in reactors. Practical lessons from the field have brought continuous upgrades in moisture resistance, bulk packaging, and calibration instructions relevant to dosing systems commonly used today.

    In heavy industry, where water systems face rapid scaling or deposits from recirculated water, the product's gentle sequestrant action prevents buildup and corrosion-related shutdowns. Over the years, we tuned our process to minimize insoluble fractions—a step that demands both tight filtration and worker vigilance during packaging. Shipments often include supplementary guidelines and working ranges, based on learnings from customer installations.

    For clients with concerns about effluent and regulatory thresholds, technical support and documented performance data on heavy metal compatibility remain front and center. The dialogue with environmental labs ensures continued compliance with phosphate and sodium load limits, creating a feedback loop that keeps both us and our clients ahead of changing laws.

    Continuous Evolution in Process Design

    Manufacturing sodium phosphate monobasic monohydrate is not a set-and-forget process. Every year brings new requirements, whether rooted in regulatory changes, industry-specific formulation challenges, or feedback about handling and storage. Our operational upgrades stem from time spent on production lines across sectors, absorbing lessons from buyers and operators who see the product in use, often under less-than-ideal conditions.

    Automation and real-time tracking now complement much of our process, with sensors measuring humidity during drying and weight checks at each transfer stage. While technology eliminates some errors, what keeps improvement going is the team’s expertise and willingness to take input from all levels—floor workers, QC analysts, and client technical managers.

    Packaging keeps evolving too. Growing demand for smaller portion-packs and specialty food-grade liners prompted us to invest in flexible, batch-coded packaging. Large-volume users still order in drums or big bags, but flexibility on formats has let smaller producers stay efficient. Clearer batch markings now trace every lot back to root data, reflecting the trust customers place in transparency.

    Traceability, Sustainability, and Industry Trust

    Sodium phosphate supply touches issues beyond product alone: responsible sourcing for starting materials, safe and fair working conditions, energy management, and minimizing environmental footprint. Our procurement sources avoid mines or extractive processes tied to environmental abuse. We hold annual reviews of supplier practices and regularly shift contracts based on updated site audits. Our plant implements energy efficiency measures—heat exchangers and real-time monitoring cut down both costs and emissions during drying and crystallization.

    For customers, transparent declarations on sourcing and environmental impact become as important as chemical purity. Participating in voluntary sustainability programs and sharing our data through third-party audits equips clients with the information they need for certifications or downstream reporting.

    Industry trust grows with decades of honest interaction and technical engagement. We view every inquiry as both a challenge and an opportunity to refine the product or its handling. Open feedback channels, prompt technical support, and public support for evolving regulatory guidelines keep dialogue straightforward and productive. Sodium phosphate monobasic monohydrate continues to underpin so many daily essentials—stability in food, consistency for diagnostics, safety in water treatment—because every kilogram delivered reflects the learned experience behind it.

    Looking Ahead: Adaptability in Changing Markets

    The sodium phosphate market evolves with each passing year, influenced by new food, pharmaceutical, and industrial trends. Increased focus on clean label and clear source declaration makes documentation and open communication more relevant than ever. Market research and technical discussions point to a steady demand for high-purity, tightly specified material in both bulk and specialty forms.

    Our response comes from the production floor up—not through abstract promises, but through continuous process checks, supply chain audits, and in-person engagement with users. Building trust and staying adaptable in real-world conditions ties together our past lessons and future goals. In the end, sodium phosphate monobasic monohydrate’s value grows not only from its function, but from a production story measured in honest effort, technical rigor, and the relationships built one order at a time.