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Sodium L-Ascorbyl-2-Phosphate

    • Product Name Sodium L-Ascorbyl-2-Phosphate
    • Alias Sodium Ascorbyl Phosphate
    • Einecs 256-483-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    891149

    Inci Name Sodium L-Ascorbyl-2-Phosphate
    Other Names Sodium Ascorbyl Phosphate
    Cas Number 66170-10-3
    Molecular Formula C6H6Na3O9P
    Molecular Weight 322.06 g/mol
    Appearance White to off-white powder
    Solubility Water-soluble
    Ph Range 7.0-8.5 (1% solution)
    Stability Stable under normal storage conditions; more stable than ascorbic acid
    Function Antioxidant and skin-brightening agent in cosmetics
    Usage Level 0.2% - 3% in cosmetic formulations
    Einecs Number 265-604-4
    Melting Point Decomposes above 200°C
    Odor Odorless
    Storage Conditions Cool, dry place away from light and moisture

    As an accredited Sodium L-Ascorbyl-2-Phosphate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White, sealed plastic drum containing 25 kg of Sodium L-Ascorbyl-2-Phosphate; label displays product name, weight, batch number, and manufacturer.
    Shipping Sodium L-Ascorbyl-2-Phosphate is shipped in tightly sealed, light-resistant containers to prevent degradation. It should be kept dry, protected from sunlight, and transported at ambient temperature. Proper labeling, including hazard identification and handling instructions, ensures safe delivery. Complies with relevant local and international chemical shipping regulations.
    Storage Sodium L-Ascorbyl-2-Phosphate should be stored in a tightly sealed container, protected from light and moisture, at a temperature between 2–8°C (refrigerated). Keep it in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers and acids. Avoid exposure to air for prolonged periods to prevent degradation and maintain stability.
    Application of Sodium L-Ascorbyl-2-Phosphate

    Applications of Sodium L-Ascorbyl-2-Phosphate in Industrial Manufacturing

    As a stable, water-soluble vitamin C derivative, Sodium L-Ascorbyl-2-Phosphate plays a critical role in a select range of regulated downstream industries. Drawing from our manufacturing expertise, we carefully align our raw material with highly specific, high-value application scenarios, each subject to strict quality, safety, and process requirements.

    1. Cosmetic Skin Brightening Solutions

    Leading cosmetic formulators use this ingredient in advanced skin brightening and anti-aging serums, day creams, and facial masks. It delivers antioxidant protection and enhances skin tone by supporting tyrosinase inhibition under industrial production protocols. Our supply closely matches the purity and stability demands of both high-volume and boutique OEM manufacturers in the cosmetics sector, where consistency and reliable batch performance directly impact consumer trust and regulatory market access.

    Industry compliance standards

    • EU Regulation (EC) No 1223/2009 on Cosmetic Products
    • China National Medical Products Administration (NMPA) Cosmetic Supervision and Administration Regulation
    • US FDA Title 21 CFR 701/740 for Cosmetic Labeling
    • ISO 22716: Cosmetic GMP

    Typical usage ratio

    • 0.2%–3% (w/w), adjusted for product type and regional regulatory restriction; higher concentrations limited by irritation risk and label claims

    Downstream process integration

    • Added into water phase during emulsification, with pH carefully adjusted between 6.0–7.5 to maintain ingredient integrity
    • Requires chelating agents and antioxidants in formulation to stabilize against oxidation during industrial mixing and filling operations

    Final product types

    • Whitening serums
    • Anti-aging creams
    • Sheet face masks
    • Skin tone-evening lotions

    2. Medical Dermatology Preparations

    In regulated topical medicines, particularly those developed for post-procedure recovery or adjunctive dermatology treatments, hospital compounding pharmacies and pharmaceutical manufacturers incorporate Sodium L-Ascorbyl-2-Phosphate owing to its stability compared to ascorbic acid. This active supports collagen synthesis and wound healing and must satisfy pharmacopoeial purity norms for use in medicinal gels and ointments dispensed via prescription or hospital supply.

    Industry compliance standards

    • United States Pharmacopeia (USP) Monograph
    • European Pharmacopoeia (Ph. Eur.)
    • Good Manufacturing Practices (ICH Q7, GMP for APIs)
    • ICH Q1A (R2) Guidelines for Stability Testing

    Typical usage ratio

    • 1%–5% w/w, determined by dose-response data; higher levels employed in prescription formulations subject to toxicology review

    Downstream process integration

    • Dissolved into sterile aqueous gel bases post-autoclaving, followed by pH adjustment
    • Final filled under aseptic conditions into aluminum tubes or airless dispensers to prevent oxidative degradation

    Final product types

    • Professional dermatology post-peel recovery gels
    • Hospital wound healing creams
    • Prescription-grade anti-pigmentation ointments

    3. Functional Oral Care Formulations

    Dental care product manufacturers value this ingredient for advanced toothpastes and mouth rinses targeting gum health and oral antioxidant support. Thanks to its higher stability in aqueous environments, it is preferred over conventional vitamin C in formulations aiming for labeled claims on gingival repair and plaque control, with effective concentrations governed by food safety and pharmaceutical guidance in major markets.

    Industry compliance standards

    • China GB 8372-2017 and GB 22115-2008 for Toothpaste Safety
    • US FDA Monograph for Anticaries and Oral Rinse Ingredients (21 CFR Parts 355/356)
    • ISO 16128 for Natural and Organic Personal Care
    • EU Cosmetics Regulation (EC) No 1223/2009

    Typical usage ratio

    • 0.02%–0.3% (w/w), balanced for flavor acceptability and stabilization with other functional agents (e.g., fluorides, xylitol)

    Downstream process integration

    • Premixed into hydrated silica or sodium phosphate base at low temperature to minimize loss
    • Incorporated during final blending prior to packaging in laminated tubes or mouthwash bottles

    Final product types

    • Antioxidant toothpastes
    • Oral gel sticks for gingival protection
    • Functional mouth rinses supporting gum repair

    4. Fortified Animal Feed Additives

    Commercial aquafeed and specialty pet food producers have adopted this ingredient to stabilize vitamin C levels in pelleted feeds for fish, shrimp, and sensitive mammals, ensuring effective nutritional delivery across extended storage and water exposure. The direct impact on animal immunity and tissue repair mandates tight conformity to food additive directives and animal nutrition guidelines in global markets.

    Industry compliance standards

    • EU Regulation (EC) No 1831/2003 on Additives for Animal Nutrition
    • US FDA 21 CFR Part 573 (Food Additives Permitted in Feed and Drinking Water)
    • China GB/T 17812-2018 for Premix Feed Additives
    • FAMI-QS Code of Practice for Feed Additives

    Typical usage ratio

    • 35–125 mg/kg feed, titrated based on species, growth stage, and storage conditions; higher end used for aquaculture due to loss from extrusion and water leaching

    Downstream process integration

    • Blended into vitamin premix or directly into feed mash prior to extrusion or pelletizing stages
    • Heat-stable up to 130°C, suitable for industrial feed processing and subsequent coating stages

    Final product types

    • Vitamin-stabilized aquatic feeds (shrimp, tilapia, salmon)
    • Growth and health enhancement pellets for pet fish and small mammals
    • Premix blends for commercial animal husbandry
    Free Quote

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    Certification & Compliance
    More Introduction

    Sodium L-Ascorbyl-2-Phosphate: Exploring Stability and Performance in Vitamin C Derivatives

    Our Manufacturing Journey—Commitment to Reliable Performance

    In our decades running production lines, Sodium L-Ascorbyl-2-Phosphate (SAP for short) keeps proving itself. Vitamin C, or ascorbic acid, grabbed everyone’s attention for skin care and supplements. Its flaws—fragile and quick to break down—drove us to innovate. Our plant focuses on SAP for one key reason: it holds up where pure ascorbic acid falters. SAP doesn’t turn brown or lose function after hitting the air. We built our production around strict controls to keep every bag as clean as possible, batch after batch. Hydrolysis, trace metals, and pH trips up pure vitamin C. SAP takes those knocks in stride. We tested it against heat, light, and repeated product formulation runs—our process delivers material with consistent VC content and free from excessive moisture or heavy metal traces.

    Understanding SAP—What Makes It Work?

    The backbone of SAP lies in coupling ascorbic acid with a stable phosphate group. As sodium salts, these molecules dissolve fast and carry through water-based blends without fuss. This phosphate link doesn’t just slow oxidization; it stops vitamin C from reacting too early with other formula ingredients. We measure each batch with HPLC and keep a close eye on residual solvents and microbial markers, going beyond standard food and cosmetic grades. Formulators trust SAP’s stability not just because of the molecule, but because they know our lines don’t leave room for contamination or “off” flavors and colors. Our teams run small-scale pilot tanks alongside large reactors, making sure process tweaks actually work in the full-scale system.

    Clear Specifications and Straightforward Applications

    SAP shows its best qualities in the right context. We produce it as a white or almost-white powder, with a minimum vitamin C content above 98 percent by dry basis. Its sodium content and phosphate presence help it dissolve fast into aqueous products—like lotions, clear serums, dental gels, and food supplements. SAP keeps the active vitamin C locked in until your formula gets rubbed onto skin or swallowed and the body’s own enzymes break it down. This design cuts down waste and supports real, measured activity over longer shelf lives.

    The moisture content stays below set limits—usually less than 1%. Our internal labs check each lot for absence of harmful heavy metals, always keeping lead, arsenic, and mercury well under global thresholds. We watch for microbial counts, making sure products stay clean even before they enter preservative-packed final goods. Formulators who want to avoid parabens or synthetic stabilizers have more freedom with SAP because our batches resist degradation on their own.

    Experience Across Industries—Skin Care, Nutrition, Household Uses

    SAP climbs up into all sorts of finished products, and our experience backs it. In skin care, chemists grab SAP for brightening creams, spot correctors, or lightweight serums. They want skin to see vitamin C’s effects—fading discoloration, boosting collagen—without their entire batch turning unstable after a few weeks on the shelf. SAP stands up to the demands of oil-in-water emulsions and gels. We’ve helped small skin care labs and massive international lines get through tricky formulations where pure ascorbic acid either broke down, gave off odor, or separated from the base.

    Supplement manufacturers seek SAP’s super-stability for powders, chewables, and tablets. Pure vitamin C leaves their operations with headaches like discoloration or the sharp taste kids balk at. SAP makes chewable and fizzy tablets possible, since it cancels out some aftertaste and fights oxidized “off” notes when open to air or blended with minerals. We learned, through repeated pilot testing, how SAP behaves with magnesium and zinc salts, or how pH adjustment in the granulation step lets flavors and functional additives stay crisp. Our support doesn’t end with a COA; we work alongside partners as formulas scale from test batch to production drums.

    Personal care goes beyond skin. SAP’s solubility lines up with dental pastes and fortifies rinseable products. It offers fresh brightening without rough abrasives or peroxide-related sensitivity. Some household or wound care sprays add SAP where antioxidant and anti-irritant properties give practical benefits. We stay close to our customers as regulations change and claims need new science.

    SAP Compared to Other Vitamin C Options—Direct Insights

    Competing vitamin C forms pop up regularly: L-ascorbic acid, magnesium ascorbyl phosphate, ascorbyl palmitate, and more. We produced most of these at some point. Each one comes with tradeoffs. Pure ascorbic acid, strong and cheap, suffers from poor shelf life—our customers report brown spots and fading potency even inside airless pumps or dark glass. Magnesium ascorbyl phosphate (MAP) works well for certain skin systems but comes with higher electrolyte interference and sometimes gritty texture in serums. MAP often raises the final product cost because of the expensive magnesium salts and more alkaline pH requirements.

    SAP’s main edge is clear: faster and full dissolution in water, almost neutral pH, and excellent tolerance to both heat and light. This opens up clear serums in PET bottles, non-refrigerated food supplements, and travel-friendly sachets. SAP doesn’t generate gritty sediments in reconstituted drinks. Our team learned that SAP provides a steadier flow during tableting or spray-drying, cutting waste and reducing “fish-eye” lumps in blends. Ascorbyl palmitate, a fat-soluble form, serves specialty uses in lip balms or fatty creams but lags behind SAP for bioavailability and ease of dosing. We walk partners through the practical side—storage, shipping, batch records—because every skipped quality check costs time and money.

    Some buyers come to us wondering if SAP’s phosphate group drags down activity. Clinical data and industry research say otherwise. SAP gets taken up and converted into active ascorbic acid by the body and skin, letting users see real vitamin C effects. We believe process controls matter as much as chemistry. Batches with trace oxidants or excess moisture underperform, so we keep titration and chromatographic records on each drum for full traceability.

    Supplier Value—Beyond Paper Guarantees

    Long-run stability isn’t just a product claim on a sheet. We back up SAP’s stability with storage tests. We run accelerated aging trials at 40°C and high humidity. Our technical team tracks changes in color, active content, and solubility. Every lot has a retention sample on record. Customers large and small ask for support when something unexpected crops up—a pH drift, a formula color shift, or a taste issue. Our team doesn’t disappear after loading pallets. We share technical notes, raw data, and process learnings so partners can debug their systems faster.

    We keep SAP in drums designed for moisture and air control, not just lined cardboard. Our in-house logistics crew understands the sensitivity of nutrients, especially to shifting warehouse temperatures. Some clients told stories of shipments bought from brokers arriving clumped or off-white. We manage first-in, first-out inventory and regular audits, keeping emergency stock when natural disasters or holidays disrupt global supply chains.

    Certification matters to international buyers. We invest in kosher, halal, and ISO-driven audits. These are not just marketing points—they set the quality bar where it matters. We avoid synthetic preservatives or carriers unless requested, letting SAP stay as close to the raw molecule as possible. Customers with allergen concerns or label transparency requirements can rely on our process transparency.

    Supporting Sustainability and Global Distribution

    Every vitamin C derivative brings sourcing challenges. We source raw materials with full traceability and work with partners focusing on environmental responsibility. Some industries want “vegan” or botanically-derived as requirements grow stricter. SAP, thanks to its chemical structure, meets most vegan and non-GMO labeling rules. Our team ensures each chemical step keeps waste streams minimal and recycles as much process water as technology allows. Regulations vary by country, especially for supplements. We make sure our paper trail matches not only China’s GB standards but also the needs of EU and US regulatory agencies.

    Packaging orders for far-off destinations brings its own lessons. Hot, wet climates demand extra packaging layers—vacuum seals or secondary liner bags, not just bulk drums. Our materials survive these journeys without unexpected caking or potency loss. We document best-by dates based on in-house storage trials, not just industry averages. This supports our customers in making shelf-life claims, especially in quality-focused retail markets.

    We work to cut environmental impact through better logistics. Local warehousing, efficient sea shipment, and smart batch sizing make sure partners never run dry or hold back-logged, near-expiry stock. Rapid response to recalls or out-of-spec findings keeps SAP’s reputation high in a world crowded with lookalike commodity suppliers.

    Feedback Loop—Learning From Real Users

    Stability figures and lab claims ring hollow without honest feedback. We run post-marketing surveillance alongside partners testing SAP in new food or skin care launches. Our R&D team asks for customer batch performance, checks out real-world color shifts, and takes action if batches trend away from targets. Over years working with both fortune 500 manufacturers and small-batch brands, we’ve learned which alleys to avoid: loose drum liners, unreliable moisture controls, inadequate metal screening. Each customer call teaches something new. We shifted our impurity controls, for example, after one beverage partner detected trace ions dulling their vitamin C drinks.

    End-users drive our improvements as much as regulatory enforcement. Our R&D director keeps a running log of oddball compatibility cases—enzymatic drink mixes, unstable fragrance blends, or harshly acidic serums. SAP’s strong point remains its mildness, non-irritating at recommended levels. But industries push new boundaries every year. Our plant invested in smaller-batch reactors to support limited-series trials for new textures or co-formulation tests with less mainstream actives.

    Common Myths, Best Practices, and Troubleshooting

    Some buyers worry SAP will “lock away” vitamin C so tightly the body can’t use it—reality shows SAP’s release inside cells or after ingestion matches or tops rival forms for most uses. Occasionally clients expect SAP to fix every formulation problem; it has limits. Oil-only formulas see little advantage. Extremely acidic or very alkaline systems might still challenge stability.

    Our technical support answers many requests: from dissolving tips (always use lukewarm water and slow addition), to blending with botanicals or flavors (add SAP before oils, right after chelators). We’ve seen customers blend SAP too early during emulsification, frying its content above 80°C. Keeping the temperature in check during manufacturing protects the material. Correct pH during formulation matters—even though SAP handles a range, extreme conditions still push its boundaries.

    With finished products showing haze or settling, we advise checking for oversaturated solutions, low-quality thickeners, or hidden mineral contamination. Tableters sometimes find SAP grain size affects tablet integrity—our feedstock’s tight sieve range minimizes these risks. More than one partner found that even tiny shifts in their blending order, pH adjusters, or wet granulation method made the difference between a stable, attractive tablet and a crumbly, off-color mess.

    Vision for the Future—Quality and Value Beyond Cost-per-Kilo

    As global demand for vitamin C alternatives rises, quality assurance separates top-tier manufacturers from anonymous bulk suppliers. SAP’s place as a reliable, shelf-stable ingredient is secure only so long as manufacturers remain vigilant. We see corners cut across the industry—no batch records, old stock repackaged, or untested blends sent overseas in unsealed drums. Our approach stands apart; SAP shipments never leave our plant without full documentation, traceability, and retention samples. Direct customer support, regular audits, and open-door visits build trust you can’t measure in metric tons.

    We’re watching close as industry asks more of their vitamin C sources—clean labels, minimal excipients, clear supply chains, low energy footprints. Future upgrades in our SAP manufacturing will focus on more efficient phosphate coupling, greater water recovery, and even greener sodium inputs. Every dollar invested here cuts risk for our customers, whether they launch a medical-grade skin patch or a garden-variety effervescent drink. As buyers wise up to quality shortcuts, only material that proves itself in actual products will hold market share.

    Our company’s story with Sodium L-Ascorbyl-2-Phosphate is rooted in experience and trial. By keeping our process sharp and our communication candid, we keep SAP’s value clear amid a crowded marketplace. Customers keep coming back for more than a specification—they come for a partner who will help them solve the next bottleneck, find the next efficiency, and unlock new uses for one of modern chemistry’s most trusted derivatives. Those relationships let us keep SAP not just relevant, but essential, to innovation across nutrition and personal care.