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Sodium 3,5,6-Trichloropyridin-2-olate

    • Product Name Sodium 3,5,6-Trichloropyridin-2-olate
    • Alias STCP
    • Einecs 220-768-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    675223

    Product Name Sodium 3,5,6-Trichloropyridin-2-olate
    Molecular Formula C5Cl3NNaO
    Molecular Weight 236.41 g/mol
    Appearance White to light yellow powder
    Solubility In Water Soluble
    Cas Number 13115-71-4
    Melting Point Decomposes before melting
    Storage Conditions Keep container tightly closed in a dry and well-ventilated place
    Ph Of Aqueous Solution 8-10 (1% solution)
    Odor Odorless
    Stability Stable under recommended storage conditions

    As an accredited Sodium 3,5,6-Trichloropyridin-2-olate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g white plastic bottle with a tamper-evident cap, featuring hazard symbols, chemical name, and batch details clearly labeled.
    Shipping Sodium 3,5,6-Trichloropyridin-2-olate should be shipped in tightly sealed containers, protected from moisture and incompatible substances. It must comply with hazardous materials regulations, using appropriate labeling and documentation. Transport in accordance with local and international guidelines, ensuring secure packaging to prevent leaks or spills during transit. Store in a cool, dry place.
    Storage Sodium 3,5,6-Trichloropyridin-2-olate should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from incompatible materials such as strong acids and oxidizers. Protect from moisture, direct sunlight, and sources of ignition. Label the container clearly and ensure access is restricted to authorized, trained personnel wearing appropriate personal protective equipment (PPE).
    Application of Sodium 3,5,6-Trichloropyridin-2-olate

    Applications of Sodium 3,5,6-Trichloropyridin-2-olate in Industrial Manufacturing

    Sodium 3,5,6-Trichloropyridin-2-olate serves as a key intermediate for diverse chemical processes across multiple specialized manufacturing sectors. Our facility maintains strict raw material traceability and rigorous quality screening to support end-users in regulated fields. The following sections detail critical application pathways, integration methods, and compliance parameters for this raw material in current international industry practice.

    1. Synthesis of Agrochemical Active Ingredients

    Manufacturers utilize Sodium 3,5,6-Trichloropyridin-2-olate as a core building block in the synthesis of selective herbicides, notably in pyridine-based weed control actives. Its trichloro-substituted structure enables high selectivity and efficiency in targeted crop protection products. Downstream producers rely on this intermediate for multi-step synthesis routes involving controlled chlorination, coupling, and formulation under GMP-compliant production floors. Residual content and impurity profiling follow strict thresholds to meet agrochemical registration criteria in major agricultural economies.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • REACH Regulation (EC) No 1907/2006
    • US EPA Pesticide Registration requirements (40 CFR 158)
    • GB 20811-2006 for pesticide technical requirements in China

    Typical usage ratio

    • 10–25% in initial synthesis steps, adjusted based on target molecule's desired pyridin-2-olate content and reaction yield requirements

    Downstream process integration

    • Introduced in the first or second reaction stage of multi-step agrochemical synthesis
    • Reacted with alkylating or acylating agents under controlled temperature and pH
    • Followed by solvent extraction and purification protocols
    • In-line monitoring for trichloro impurity levels

    Final product types

    • Pyridinyl herbicides (e.g., picloram, clopyralid intermediates)
    • Grass and broadleaf weed control formulations
    • Technical-grade pesticide actives
    • Pre-formulated crop protection concentrates

    2. Intermediate for Pharmaceutical Synthesis

    Sodium 3,5,6-Trichloropyridin-2-olate plays an essential role as a chemical intermediate in medicinal chemistry, specifically for the construction of heteroaryl and halogenated pyridine scaffolds. Its chemical profile provides a reactive handle for controlled nucleophilic substitution reactions in the production of active pharmaceutical ingredients (APIs). Downstream users in pharmaceutical sectors implement careful monitoring of trace impurities and solvent residues to comply with international pharmacopeial requirements and finished API purity benchmarks.

    Industry compliance standards

    • US Pharmacopeia (USP) for API intermediates
    • ICH Q3A/B guidelines on impurity limits
    • EU GMP for starting material traceability
    • WHO Technical Report Series 986 (Annex 2)

    Typical usage ratio

    • 5–18% within heterocyclic coupling reactions; precise dosage defined by molecular weight ratio and targeted substitution pattern

    Downstream process integration

    • Charged into pressure reactors or stirred tank reactors
    • Often combined with amines or alkoxy nucleophiles under solvent reflux
    • Followed by intermediate isolation and crystallization
    • Integrated within validated process validation protocols

    Final product types

    • Intermediate APIs for anti-inflammatory drugs
    • Building blocks for antiviral and anticancer compounds
    • Small-molecule investigational drugs
    • Pyridine-based pharmaceutical actives

    3. Manufacture of Industrial Biocides

    Producers of industrial water treatment and preservation chemicals deploy Sodium 3,5,6-Trichloropyridin-2-olate as a key precursor in the synthesis of specialized biocidal agents. Its high halogenation content supports the formation of strong pyridinone-based antimicrobial molecules suitable for paints, coatings, cooling towers, and process water systems. Downstream formulation lines require batch-wise dosage control and monitoring for effluent chlorinated byproducts in accordance with environmental and workplace safety regulations.

    Industry compliance standards

    • Biocidal Products Regulation (BPR, EU 528/2012)
    • US EPA FIFRA standards for microbial control agents
    • ISO 9001:2015 for industrial chemical production
    • China GB/T 21802 for biocidal additives

    Typical usage ratio

    • 8–20% as batch input, optimized based on required active concentration and microbial efficacy tests

    Downstream process integration

    • Fed into intermediate reaction tanks during biocide synthesis
    • Post-synthesis quenching and pH neutralization required
    • Filtered to minimize residual particulate
    • Discharged into automated filling and packaging systems

    Final product types

    • Industrial biocidal additives for paint and coating industries
    • Water treatment biocides for recirculating cooling systems
    • Paper and pulp microbial control agents
    • Preservation chemicals for adhesives and emulsions

    4. Input Material for Fine Chemical Synthesis

    Chemical manufacturing plants engaged in fine chemical production rely on Sodium 3,5,6-Trichloropyridin-2-olate for multi-step derivatization processes. These processes yield specialty pyridine derivatives used as ligands, catalysts, and intermediates in electronic, polymer, and specialty dye sectors. Formulators implement stringent input quality validation and real-time process monitoring to control product batch reproducibility and handle controlled substances management under international trade laws.

    Industry compliance standards

    • Chemical Facility Anti-Terrorism Standards (CFATS, US DHS)
    • REACH registration for downstream chemicals
    • ISO 14001 for environmental management
    • OECD guidelines for chemical safety and residue control

    Typical usage ratio

    • 12–22% by weight in initial synthesis charges, with percentage tuned based on desired functional group conversion and solvent loading

    Downstream process integration

    • Charged into reaction systems for ring functionalization
    • Paired with halogen exchange or oxidative coupling procedures
    • Sequential purification by extraction and crystallization
    • Quantitative LC/MS analysis of product fractions

    Final product types

    • Pyridine-derived ligands for metal-catalyzed processes
    • Electronic grade additives
    • Intermediate dyes and pigment precursors
    • Fluorescent markers for analytical chemistry
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    Certification & Compliance
    More Introduction

    Sodium 3,5,6-Trichloropyridin-2-olate: A Chemist’s Perspective on Quality, Application, and Manufacturing Mastery

    Our Dedication to Crafting Sodium 3,5,6-Trichloropyridin-2-olate

    After decades refining the synthesis of specialized pyridinic salts, we have found that customers often bring problems to our technical desk that only arise out on the production floor. For many, the clarity and purity of Sodium 3,5,6-Trichloropyridin-2-olate (model: TCPO-Na) signal more than simple product quality; they reflect robust manufacturing discipline. We see this chemical not as another commodity, but as a linchpin for critical transformations in agrochemical intermediates and specialty reactions. As direct manufacturers, each decision—precursor sourcing, reaction conditions, impurity profiles—anchors our confidence in the product that enters your process.

    Why Product Consistency Matters for Large-Scale Users

    Industrial formulators and process engineers have spent years dealing with off-spec shipments from general traders and anonymous suppliers. Batch-to-batch uniformity of our TCPO-Na ensures seamless integration into downstream synthesis. Factors like bulk density, granular homogeneity, and minimal chlorinated byproducts draw a clear line between genuine manufacturers and casual repackers. We design our sodium 3,5,6-trichloropyridin-2-olate with end-use reliability in mind, aiming for moisture content below 0.5% and color indices that won’t introduce havoc into color-sensitive production. By and large, firms who require total traceability and predictable solubility gravitate towards producers who can discuss the reaction mechanism, not just the label.

    The Model We Produce: TCPO-Na Technical Report

    At our facility, the TCPO-Na we produce boasts an assay typically over 98% by HPLC, made possible only by the close proximity of analytical teams to our main reactors. From the careful chlorination of intermediates to the final neutralization step, we scrutinize impurities like residual solvents and dichloro analogs. The product crystallizes into a high-stability powder, resisting caking during export even under tropical transit routes. We test each drum for heavy metals and organic contaminants, recognizing that even trace loads can disrupt catalytic or biological systems for end users. Each drum leaving our plant carries not only a certificate, but also the credibility built over batches where quality holds up laboratory claims in the real world.

    Common Applications and Real-World Experience

    Sodium 3,5,6-Trichloropyridin-2-olate plays a central part for many of our customers in the crop protection field, especially where the creation of chlorinated pyridine rings is necessary for active ingredient synthesis. In herbicide production runs, the downstream purity of the active is often dictated by the start material—meaning our product passes directly into the quality test data of the finished goods. Our collaborations with process chemists in plant health have taught us that low solubility byproducts can slow down reactors or foul up filtration steps, leading to cascading inefficiencies if not controlled at source. A chemical plant running on schedule does not tolerate unpredictability in salt solubility, particle size, or flowability—all considerations we incorporate into our design and packing for TCPO-Na.

    Besides agrochemicals, specialty water treatment applications value the unique reactivity profile of this compound. Customers have configured batch and continuous processes around its stability in strongly oxidizing and alkaline conditions. Over the past years, they have reached out to us for technical support fine-tuning feeds and water pH so that products dissolve cleanly with minimal sludge. Direct communication with manufacturing chemists and stack operators has refined our understanding of what it means to supply a truly fit-for-purpose material rather than a generic blend.

    Key Differences from Commercially Available Alternatives

    We regularly field calls from buyers who find that not all sodium trichloropyridinolate is created equal. Some of the market supply represents reprocessed or downgraded material, often with higher levels of sodium chloride from incomplete washing. These variants leave crust on tank walls or deposit insolubles into filtration units—problems best understood by those who spend time in manufacturing suites. Our TCPO-Na features reliably low alkalinity, avoiding corrosion of stainless steel pumps and precision dosing equipment common to advanced production sites. Customers rely on our analytical support, including detailed impurity spectra, because cutting corners at the raw materials stage eventually surfaces as finished-product recalls or production stoppages.

    Unlike unnamed bulk product with ambiguous origin, all of our output originates from one cohesive line, subject to a quality assurance program designed alongside major downstream users. Many traders blend or split lots throughout distribution networks, so users lose control over upstream production parameters. In contrast, our production logs allow us to pinpoint fault causes in case of any unusual performance in your plant – something a trader rarely provides. This single-source approach matters most for regulated industries that must document every kilogram from reactor to application.

    Refining Purity and Removing Trace Impurities: Our Manufacturing Story

    We built our facility specifically around the quirks of trichloropyridine chemistry, expanding filtration, refining solvent recovery, and automating drying to limit thermal degradation. Each reactor batch is monitored for temperature excursions and controlled by chemists who understand the reaction pathway. In certain production campaigns, a minor slip in pH or batch timing can shift the balance of byproducts, as our process engineers have seen during scale-up. Through detailed audits and raw materials vetting, we have driven impurity levels to a minimum, often catching issues before QC picks them up. A knowledgeable team and veteran operators keep deviations in check, delivering a product that plant operators welcome into their high-throughput lines.

    On several occasions, plant trials at customer sites have surfaced problems invisible from the laboratory bench—distinct odors, unexpected foaming, or unanticipated carryover of trace solvents. Our technical exchanges with partners often uncover nuances in filterability or chemical reactivity that only appear during large-scale production, far away from the safety of a kilogram flask. Rather than dismissing these operational details, our manufacturing chemists incorporate the lessons directly into ongoing process upgrades, such as adapting drying temperatures to customer-specific needs or modifying the neutralization regime.

    Stability, Shipping, and Storage: Simple Solutions, Real-World Lessons

    Even the best chemical can lose performance if it degrades or absorbs moisture during storage. Having seen dozens of customer complaints about lumpy drums or surface discoloration from competitors’ goods, we invested early in moisture barrier packaging and nitrogen-purged containers for extended transit. Our SOPs dictate immediate sealing and storage below critical humidity levels once drying completes. Field feedback confirmed that these precautions matter when chemical drums may spend days in ports or warehouses without temperature control. By the time drums reach your mixers or reactors, the material remains free-flowing and consistent—a product feature made possible not by a certificate, but by an organizational culture that anticipates real-world logistics.

    Some customers in warmer climates expressed concern over stability during transport. We tested product under simulated tropical conditions for periods exceeding several weeks and recorded no loss in active purity or clumping. That reliability under adverse conditions, based on verification and adaptive packaging, distinguishes a dedicated manufacturer from a casual vendor.

    Supporting Operational Efficiency Through Technical Service

    Chemical supply isn’t only about the carton count and delivery date; it involves deep technical engagement with those running production lines, batch reactors, and synthesis development labs. Sometimes a minor physical property, such as dusting tendency or solution clarity, creates bottlenecks where productivity hangs in the balance. Many requests for incremental improvements reach us through daily conversations, not just annual surveys. One example involved a formulation plant reporting filter clogging apparently related to subtle impurities. By tracing each step of their incident back to our own process logs, we isolated a cause linked to raw material dilution and adjusted protocols. Post-adjustment, repeat issues disappeared, translating to faster throughput and less downtime—a direct, measurable benefit from in-house manufacturing oversight.

    Providing specification sheets only tells a fraction of the story. Regular exchange with users gives us insight into operational priorities: cleaning ease, minimal dust, reactivity, and stable shelf life. We maintain a technical team on standby to answer questions without passing them through layers of intermediaries. For production managers coping with yield drops or unexplained color changes, this direct manufacturer access shortens resolution times and prevents significant losses in commercial production.

    Environmental and Regulatory Commitment

    As a chemical manufacturer, the responsibility for environmental stewardship runs parallel to the pursuit of product excellence. Over the years regulators have elevated expectations for effluent control, worker safety, and batch traceability. We designed our plant with advanced scrubbers and multi-stage wastewater treatment to limit the release of chlorinated species. Every process update carries the goal of maintaining compliance with national and international laws, reducing not only regulatory risk, but also minimizing downstream environmental impact for customers.

    Our technical team assists partners in documentation needed for regulatory filings, including detailed origin records and impurity breakdowns. Such transparency only comes from direct control over the full production pathway, something not even the most diligent distributor can retroactively reconstruct. Long-term buyers appreciate that working with us means easier compliance audits and fewer surprises from sudden regulatory changes that can upend well-established supply chains.

    Adapting to Shifts in the Industry and Scaling Up

    Changing customer priorities—whether for greener synthesis, lower-cost solutions, or faster supply—drive our continual reinvestments in process engineering. Recent years saw a push toward minimizing solvent use, motivating us to adopt solvent recycling and closed-loop systems wherever technically possible. On more than one occasion, a large end-user’s scale-up campaign exposed new requirements for trace impurity profiles never previously requested. Instead of shoehorning legacy approaches into new contexts, we routinely re-examine core reactions and adapt them to emerging demands.

    Scaling up also shifts the chemistry dynamic. What works at pilot scale might drift at production volume, requiring vigilant monitoring rather than blind trust in the numbers. We have experienced how minor fluctuations in raw material quality can propagate into macro-level process issues when volumes climb. Daily meetings bring together R&D, quality, and plant operations so corrective actions can be taken long before drum filling.

    Sometimes entry into new applications—such as fine-tuning sodium 3,5,6-trichloropyridin-2-olate for advanced material synthesis or specialty intermediates—means introducing new grade lines with ultra-low impurity requirements or adjusted physical properties. Rather than simply offering stock material, we rely on a dialogue with downstream chemists to set the most relevant target specifications. Previous projects in contract manufacturing have shown that direct feedback loops between our facility and your lab can mean the difference between an on-spec batch and a costly failure.

    Comparing Direct Manufacturing to Distribution-Heavy Supply Chains

    Trust in chemical procurement starts with understanding production origin. Many users have encountered “equivalent” materials only to discover performance is compromised by variable grades, reblending, or mislabelling throughout a chain of handlers. By controlling synthesis from raw input to finished drum, we tell users exactly what went into their delivered lot. Distributors frequently can’t answer technical questions or troubleshoot process deviations, while we retain batch histories and hands-on knowledge of real chemical behavior in reactors and at scale.

    This capability means customers attain both product predictability and support. Resolving a sulfonation side reaction or reducing the risk of reaction quench failures stems from shared expertise, not generic data sheets. We frequently assist in process validation and help laboratories network with real production staff, not just remote email contacts. Our role rarely ends at shipment. We regularly help interpret instrumentation anomalies and offer insight from past troubleshooting efforts across plants globally.

    Outlook: Building for the Next Generation of Users

    Future customers will bring new challenges—demanding fewer environmental burdens, more sustainable supply, and faster turnaround from pilot to full-scale production. Our deep understanding of pyridinic salt chemistry and the hard lessons earned through decades of manufacturing help prepare us for this changing landscape. We keep a running dialogue open with researchers shaping new synthetic routes, operators driving plant improvements, and procurement teams watching for hidden value.

    Our experience shows that successful partnerships grow through technical transparency, continuous process feedback, and willingness to adapt. The Sodium 3,5,6-Trichloropyridin-2-olate delivered from our site comes with an open channel for these critical exchanges, supported by a team who has turned chemistry into both craft and profession.