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Sodium 2-Amino-1,4-Benzenedisulfonate

    • Product Name Sodium 2-Amino-1,4-Benzenedisulfonate
    • Alias Tobias Acid
    • Einecs 226-376-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    120118

    Chemical Name Sodium 2-Amino-1,4-benzenedisulfonate
    Cas Number 88-63-1
    Molecular Formula C6H6NNa2O6S2
    Molecular Weight 317.23 g/mol
    Appearance White to off-white powder
    Solubility In Water Highly soluble
    Melting Point Decomposes before melting
    Ph 1 Solution Approximately 7-8
    Odor Odorless
    Synonyms Sodium 2-Aminobenzene-1,4-disulfonate
    Storage Conditions Store in a tightly closed container, in a cool, dry place
    Stability Stable under recommended storage conditions

    As an accredited Sodium 2-Amino-1,4-Benzenedisulfonate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging is a sealed, amber glass bottle containing 500 grams of Sodium 2-Amino-1,4-Benzenedisulfonate, labeled with safety information.
    Shipping Sodium 2-Amino-1,4-benzenedisulfonate is shipped in tightly sealed containers, protected from moisture and incompatible substances. The packaging ensures compliance with relevant chemical safety standards. Appropriate labeling, documentation, and handling instructions accompany each shipment to ensure safe transport by ground, sea, or air according to applicable regulations.
    Storage Sodium 2-Amino-1,4-benzenedisulfonate should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from moisture and incompatible substances like strong oxidizers. Protect from light and sources of ignition. Ensure the storage area is labeled and that chemicals are kept at stable temperatures, ideally in a designated chemicals cabinet or storeroom.
    Application of Sodium 2-Amino-1,4-Benzenedisulfonate

    Applications of Sodium 2-Amino-1,4-Benzenedisulfonate in Industrial Manufacturing

    Sodium 2-Amino-1,4-Benzenedisulfonate serves as an essential intermediate in multiple sectors demanding strict quality and process performance. We supply tailored grades meeting the needs across diversified high-volume chemical industries with established technical and regulatory requirements.

    1. Dyes and Pigments Formulation

    Colorant manufacturers incorporate this material in azo dye synthesis, particularly for dispersions and metal complex dyes used in textiles, plastics, and ink industries. Its sulfonate groups enhance water solubility and colorfastness, while the amino functionality facilitates efficient diazotization coupling. The material enters the workflow during the initial diazo component synthesis, reacting with appropriate coupling agents under controlled pH to yield target chromophores. Product quality depends on purity, particle size, and batch-to-batch consistency, impacting dye stability and reproducibility for downstream applications.

    Industry compliance standards

    • OEKO-TEX® Standard 100 (applicable to finished textile dyes)
    • REACH Regulation (EC) No 1907/2006
    • ZDHC Manufacturing Restricted Substances List (MRSL)
    • ISO 9001:2015 Quality Management System

    Typical usage ratio

    • 5%–20% of total diazo component mass in pigment and dye batches
    • Dosage adjusted by target shade intensity and solubility requirements

    Downstream process integration

    • Added during diazotization and coupling steps
    • Integrated with auxiliary dispersants and stabilizers based on target application (fiber, plastic, ink)
    • Requires precise pH control (2–4) for reaction kinetics
    • Batch filtration and drying prior to finishing and quality testing

    Final product types

    • Synthetic textile dyes for cotton and wool
    • Pigment dispersions for polymer coloring
    • Printing inks for packaging and graphics
    • Digital inkjet colorants

    2. Electroplating Additive Synthesis

    Users in the surface finishing industry employ the compound as a brightener and leveling agent precursor in nickel and zinc electroplating processes. It undergoes controlled sulfonation and further chemical modification before blending into additive concentrates. These concentrates enable uniform metal deposition and gloss improvement in electroplated layers, reducing pitting and promoting fine-grain morphology. Consistency in raw material impurities is critical to avoid defects and maintain plating bath stability, supporting high-throughput lines in automotive, electronics, and hardware. Integration focuses on precise make-up around plating bath conditions and maintenance cycles aligned with GADSL and automotive APQP protocols.

    Industry compliance standards

    • ISO/TS 16949 (Automotive Quality Management)
    • GADSL Registry (Global Automotive Declarable Substance List)
    • RoHS 2011/65/EU (lead-free coating applications)
    • REACH Annex XVII restrictions

    Typical usage ratio

    • 0.1–0.5 g/L in nickel or zinc electroplating baths as a formulated additive
    • Adjustment based on workpiece geometry and bath turnover rate

    Downstream process integration

    • Pre-mixed in brightener concentrate production
    • Metered dosing to working bath immediately before plating cycles
    • In-line monitoring of additive concentration and impurity buildup during operation
    • Periodic bath analysis to ensure compliance with surface quality parameters

    Final product types

    • Decorative nickel-plated components (automotive trims, household fittings)
    • Corrosion-resistant zinc-plated fasteners and connectors
    • Electronic connectors with high-gloss finish
    • Precision-engineered machine parts with micro-structured surfaces

    3. Pharmaceutical Intermediate Manufacturing

    Pharmaceutical synthesis utilizes the product as a reactive intermediate for sulfonated drug molecules and active pharmaceutical ingredients (APIs), especially those in antihypertensive and antimicrobial classes. The material supports complex multi-step syntheses, introducing sulfonate functionality under defined GMP controls. Process chemists rely on high-purity grades for batch hydrogenation, selective derivatization, and crystallization operations, with strict traceability. Compliance to pharmacopeial guidelines and validated impurity profiles guide usage in regulated markets. Critical quality attributes include particle size uniformity, endotoxin levels, and residual solvent content, with direct impact on downstream purification and yield.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for APIs (EU, US FDA, CFDA)
    • USP/NF monographs for relevant sulfonated APIs
    • Ph. Eur. (European Pharmacopoeia) for sulfonate-containing substances
    • ISO 14644-1 (cleanroom standards)

    Typical usage ratio

    • Varies by target API structure, typically 0.1–5 molar equivalents relative to parent aromatic compound
    • Stoichiometry based on specific synthetic route and yield optimization

    Downstream process integration

    • Introduced in sulfonation, amidation, or condensation steps
    • Handled in validated cleanrooms for quality-sensitive APIs
    • Subjected to controlled hydrogenation, solvent exchange, and recrystallization
    • Purification by chromatographic/separation means post-reaction

    Final product types

    • Sulfonated antihypertensive drugs
    • Antimicrobial sulfonamide derivatives
    • Batched API intermediates for contract manufacturing
    • Ion-exchange pharmaceutical resins

    4. Water Treatment Chemical Production

    Specialty manufacturers use the sulfonate for synthesizing complexing agents and dispersants vital to industrial water treatment formulations. It functionalizes as a core building block in the synthesis of scale inhibitors, anti-foulants, and dye-removal agents. The aromatic sulfonate structure enables stability over broad pH and temperature ranges, ensuring actives withstand recirculating cooling water, boiler feed, and effluent processes. Users prioritize low impurity content and must comply with major regulatory frameworks for direct water contact. Proper handling during blending, polymerization, and quality release ensures that downstream industrial users avoid fouling, corrosion, and unwanted color bodies.

    Industry compliance standards

    • NSF/ANSI 60 (Drinking Water Treatment Chemicals – Health Effects)
    • ISO 14001:2015 Environmental Management System
    • EPA 40 CFR 141 (Safe Drinking Water Act regulations)
    • REACH Registered for water treatment use

    Typical usage ratio

    • 1–10 wt% in finished water treatment formulations
    • Formulators adjust by hardness, scaling index, and effluent load

    Downstream process integration

    • Polymerization feedstock for anti-scalant polymers
    • Direct blending in multi-component dispersant packages
    • Tested in pilot water loops for compatibility and performance
    • Packaged as part of ready-to-dose concentrates for end-use

    Final product types

    • Industrial scale inhibitors for boilers and coolers
    • Water-soluble dye scavengers for textile effluents
    • Anti-fouling chemical concentrates
    • Municipal water pre-treatment additives

    5. Optical Brightener Manufacture

    The material enables the intermediate synthesis steps in key optical brightener (OB) production, such as stilbene-based fluorescent whitening agents for paper, detergents, and plastics. It acts as a sulfonated aromatic spacer, ensuring compatibility and high solubility when formulated with the final whitening agents. Downstream plants prioritize colorless, high-purity grades free from chromophoric impurities, preventing color shifts and yellowing in brightened products. Integration focuses on staged condensation reactions and controlled neutralization procedures, followed by fine milling and material characterization before formulation blending and extrusion.

    Industry compliance standards

    • FDA 21 CFR 176.170 (paper and board in contact with aqueous and fatty foods)
    • ISO 2467 (fluorescent whitening agents in textiles and paper)
    • REACH registration for OB substances
    • EN 648 (paper and board intended to come into contact with foodstuffs)

    Typical usage ratio

    • 10–30% as precursor in OB intermediate synthesis
    • Efficiency depends on target brightness and process yields

    Downstream process integration

    • Condensation with stilbene or biphenyl derivatives
    • Forced neutralization and filtration to remove by-products
    • Milling and granulation before OB blending
    • Batch testing for enhanced absorption and migration resistance

    Final product types

    • Paper optical brighteners for copier and writing grades
    • Laundry detergent fluorescers
    • Plastic additive masterbatches for packaging
    • Textile finishing agents for enhanced whiteness
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    Certification & Compliance
    More Introduction

    Sodium 2-Amino-1,4-Benzenedisulfonate: An Essential Tool in Dye Chemistry

    Understanding Our Specialty Ingredient

    Decades of dye chemistry have taught us to appreciate not only the versatility of aromatic sulfonates, but also the demands of scaling up synthesis for these compounds. Sodium 2-amino-1,4-benzenedisulfonate stands out among intermediates thanks to its consistency, reliability, and ease of use in downstream reactions. Our team has produced this compound in batch quantities for years, meeting both lower and higher volume dye and pigment sector requests, and supplying it to manufacturers who appreciate tight quality controls.

    This compound, which many recognize as Sodium 2-amino-1,4-benzenedisulfonate, often enters production lines as a white to off-white, highly soluble powder. We ship it according to customer preferences for moisture baseline and particle size, thanks to controlled drying and screening protocols honed by constant feedback and process adjustments. The CAS registry identifies it with the code 88-63-1, making it instantly recognizable for buyers cross-referencing international purchase lists.

    Uses and Practical Benefits in Dye Synthesis and Beyond

    Our main customers include dye manufacturers, pigment formulators, and organic synthesis teams seeking a reliable foundation for colorant and optical brightener production. The compound serves as an intermediate in the creation of azo, anthraquinone, and other specialty dyes. Two sulfonate groups at para positions significantly improve water solubility, and the ortho-positioned amino lends itself to diazotization and coupling with other aromatic partners. This core reactivity explains the compound’s central role in synthesizing dye molecules with vivid, stable tones and textile compatibility.

    Many operators in this field notice the difference between this disulfonate and similar monosulfonates or unsubstituted aminobenzenes. The extra sulfonate moiety on the benzene ring not only bumps up solubility, it also reduces color bleed on finished fabric, a feature sought after by textile mills aiming for washfastness and uniform coloration across batches. Unlike simpler substituted benzenes, this compound eliminates the need for post-sulfonation and minimizes batch-to-batch performance gaps. It helps avoid clogging and residue build-up in continuous dye bath systems, keeping equipment downtime at bay.

    Why Consistent Quality Really Matters

    In our line, consistency is not just a tagline. Intermediates set the tone for the final chemical’s performance. Manufacturing Sodium 2-amino-1,4-benzenedisulfonate poses challenges like tight pH requirements and precise sequencing of sulfonation steps. Over the years, we have adjusted our method to tackle issues like foaming, incomplete sulfonation, or inconsistent granule size. Routine sampling and in-house wet-end analysis allow us to spot deviations in assay, sodium ion content, and moisture before the product makes it to final packing.

    We prioritize this discipline because even slight variability in purity or particle size can mean the difference between a clean diazotization reaction or one riddled with by-product. Downstream this translates to brighter dyes, reduced wastewater load, and satisfied end-customers. Our monitoring aligns with current industry guidelines, relying not just on equipment, but on keen observation—colored effluent, changed solubility, or odd reaction times alert experienced operators far more quickly than paperwork or dashboards.

    Handling and Process Experience

    Bulk handlers regularly comment that bag opening, dispensing, and solution make-up with our disulfonate are straightforward. The compound’s free-flowing powder form allows for efficient dosing directly into reactors without clumping or static build-up. Incidents like caking or excessive dusting, familiar to anyone running lengthier batches, are rare due to our control over final product drying rates. Process teams using automated feeders or simple scooping benefit from lower wastage and reduced cleanup needs.

    Our crew engages with plant operators who share firsthand impressions about handling advantages. For those working in humid climates, the low residual moisture content minimizes concerns over storage or flowability. If clients require even tighter controls, we modify our drying cycle or improve liner protection in the packaging stage. Chemical engineers and batch operators appreciate the chemical’s reactivity window, noting predictability translates to fewer stop-starts during multi-stage syntheses. Bench chemists, on the other hand, notice the crisp melting point—a reliable reference for quick ID without complex instrumentation.

    Product Differences: Beyond Standard Aminobenzenesulfonates

    A focus on dual sulfonate substitution transforms a basic aromatic amine into a potent anchor for diazo reactions. Compared with 2-amino-1-benzenesulfonic acid, the disulfonate delivers improved migration into aqueous solutions, speeding up batch times during dye paste preparation. Substitution pattern influences color strength too—end dyes prepared from the 1,4-disulfonate yield deeper and more consistent shades, and resist breakdown during high-temperature textile applications.

    Many of our partners report fewer off-odors and side reactions during coupling and finish applications when using the double-sulfonated raw material. The straightforward, predictable chemistry allows manufacturers to compress process times, improving throughput. Cost comparison often shows a slight premium for the more highly substituted amine, but process savings and end-product appeal justify the decision in every cost analysis we’ve reviewed.

    Environmental and Technical Commitments

    Anyone working at scale in this field must respect the burden of wastewater and spent liquor management. Disulfonated aromatics, including Sodium 2-amino-1,4-benzenedisulfonate, generally produce cleaner, lower-load effluents because the higher solubility leads to more complete reaction and off-loading of residual color bodies. Plant teams running modern closed-loop water systems recognize how reliable intermediates help them hit environmental targets with less reliance on post-treatment flocculants or oxidizers.

    Years ago, regulatory pressures kept increasing around effluent color and salt discharge. Our experience showed that shifting customers towards this highly substituted aromatic, with its greater water solubility and less residual by-product, lowered plant compliance costs. This effect doesn’t stem just from chemistry textbooks—it comes from regular audits, daily interactions with effluent plant attendants, and engineers fine-tuning treatment plant settings. The process can always improve, and we continue bench testing to further minimize carry-over and reduce treatment burden.

    Adaptability Across Colorant Sectors

    Sodium 2-amino-1,4-benzenedisulfonate offers versatility beyond traditional textile markets. Paper coloration, particularly where food contact safety and bleed resistance take priority, benefits from this ingredient’s unique properties. Water treatment teams rely on its fast dissolve and low residue characteristics in processes ranging from analytical detection methods to brightening paper pulps. Ink and pigment sectors, and even some specialty plastics coloration lines, find value in the compound’s ability to anchor color intensity during extrusion or blending.

    Across these sectors, process feedback loops have helped us adjust our sieve fraction and moisture targets—not always cutting-edge, but vital for keeping the product easy to add and free from clumping, especially during long shipping routes and seasonal temperature swings. This responsiveness isn’t theory; it comes from actually running packs in and out of warehousing, and tracking which shipments survive monsoons and which lose flowability. Partners who rely on precise measurements can avoid recalculations, thanks to predictable sodium and active content.

    What Sets Us Apart as a Manufacturer

    Running small pilot lots alongside large-volume campaigns is part of everyday operations in our plant. This approach helps us catch issues early and keep learning about both our process and application fields. We stay hands-on with daily manufacturing and privy to real-world batch failures, not just idealized, textbook yields. Sharing knowledge with client process teams, visiting third-party audit labs, and troubleshooting at customer sites informs how we tackle everything from packaging improvements to minor tweaks in our reaction charge and process timing.

    Time and again, transferable lessons arise. Sometimes a subtle temperature drift at one process stage leads to trace impurities, which trigger foaming or discoloration in a later batch step. Involving the plant floor teams in regular debriefs has trimmed these incidents. Even after decades running these lines, a culture of urgent, open dialogue pays off, not just for consistency but also for rapid response to supply chain changes or customer innovation.

    Maintaining Trust Through Safety and Transparency

    Plant safety remains front-of-mind at every stage, from storing precursor aromatic amines and sulfonation acids to eventually packaging the finished product. Operator training covers hazards associated with the input materials and emphasizes routine equipment checks—leaks, pressure buildup, and contamination risks receive careful attention. Transparent reporting with customers on raw material sourcing and process interventions doesn’t just keep buyers satisfied but helps build trust into every shipment.

    Documentation tracks each batch’s journey from reactor to finished sack. Quality staff cross-verify batch records, and random audit trails ensure process drift doesn’t go unchecked. Equipment teams monitor emissions, solvent storage, and post-production neutralization, keeping our impact inside evolving local and global safety standards. Routine review cycles with both local suppliers and industry working groups educate new staff and keep experienced operators from falling into complacency.

    Listening to Customers, Learning from Use Cases

    Direct feedback from downstream users shapes our approach. Dye houses with high-throughput jet dyeing machines call out dosing improvements and fewer filter blockages. An ink plant customer once highlighted better shelf-stability of their dispersions after switching over to our disulfonate. A paperboard maker noticed lower carry-over due to more complete dissolution at the start of their batch mixing. The lessons come directly from line operators, process engineers, and purchasing managers who need reliability—not only for process efficiency but also for reputational reasons.

    We log these insights alongside our own notes on operational issues: unforeseen foaming, rare shipment damage, or occasional clogging under extreme humidity. Fixes arise not from theory, but from repeat trials, vendor collaboration, and integrating operator wisdom into both process and documentation. Customer context sharing goes two ways—feedback improves product runnability, and operation notes from our side help users tweak their own practices.

    Future-Proofing Through Innovation and Partnership

    Ongoing investment in plant upgrades underpins every batch. Adopting solvent-saving process steps, smarter temperature and pH controls, and improved crystallization techniques gets attention in daily operations. We prioritize upgrades that benefit both efficiency and finished product performance, drawing on staff suggestions and third-party chemist input for solution trials.

    Research ties with textile research labs and third-party colorant specialists keep us alert to the needs of both legacy and emerging applications. Visits to textile, pulp, and pigment plants keep our team grounded in process improvements and downstream pain points. These close connections pay off—not only in the form of incremental technical advances but also in nurturing trust and practical problem-solving. Mutual respect with supply and logistics partners keeps the product moving with minimal delay, even under volatile transport conditions.

    Efficient Storage and Reliable Delivery

    Over years of filling orders, careful attention to packaging standards makes a clear mark on reliable delivery. The product stays stable in its moisture-resistant bags, protected from airborne contaminants during long shipping and warehouse storage. Warehouse staff follow batch rotation and temperature checks to keep quality stable over extended inventory cycles. Our logistics team monitors key transit points to handle delays from inclement weather or customs gluts, and alternative suppliers step in only after verifying incoming quality matches our site’s blank.

    Continuous conversations with warehouse and shipping partners alert us to damage prevention strategies, even in off-season surges or overseas shipments. Our plant management tracks shipment feedback and surface damage claims, using those to enhance packaging resilience and set clearer protocols for re-inspection at entry points and transfer depots.

    Responsibility in Production and Waste Management

    Life-cycle thinking shapes our approach to both purchasing and plant operations. Using renewable energy in select processing steps, exploiting closed-loop water processing, and managing solid waste responsibly through pre-treatment and verified offsite disposal keep the site on course with modern environmental expectations. We emphasize minimizing aromatic and inorganic discharge, and routinely re-examine operation parameters to maximize yield and recover by-products.

    Our waste steam records get checked regularly, especially during maintenance cycles. Environmental compliance teams track these data alongside global regulations, making sure product shipments do not carry unnecessary burdens to customer plants. Practical experience shows that robust up-front operation makes downstream waste easier to handle, for both client and supplier. We keep this cycle of feedback and adjustment active—all supported by direct dialogue with those who run and monitor the actual lines.

    Looking Forward: Meeting Demands for Quality, Adaptability, and Transparency

    The world asks more of chemical manufacturers each year—greater traceability, ethical sourcing, and flexibility for increasingly tailored applications. As a producer rooted in longstanding relationships with buyers, technical teams, and front-line plant operators, we keep building on years of mistakes, adjustments, and success stories. The direct touch—site visits, live phone calls with chemists, and shared troubleshooting—goes further than any sales pitch.

    Steady collaboration with textile, pigment, and paper colorant teams helps us stay close to emerging standards and market trends. Customer priorities—be it improved process yields, sustainability targets, or supply reliability—shape every batch. Real feedback, rooted in hands-on operation and field intelligence, gives both sides practical options for improvement.

    In our world, sodium 2-amino-1,4-benzenedisulfonate plays a quiet but critical role in global color production. Responsible stewardship, open collaboration, and a willingness to adapt practices make sure this specialty ingredient continues to deliver for every process it serves.