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S-N-Propyl Thioacetate

    • Product Name S-N-Propyl Thioacetate
    • Alias propylthioacetate
    • Einecs 445-330-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    673358

    Chemical Name S-N-Propyl Thioacetate
    Cas Number 2403-88-5
    Molecular Formula C5H10OS
    Molecular Weight 118.20 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 148-151°C
    Density 0.97 g/mL at 25°C
    Refractive Index 1.484-1.487
    Flash Point 45°C (closed cup)
    Solubility Insoluble in water; soluble in organic solvents
    Odor Characteristic thioester, onion-like odor
    Purity Typically ≥ 98%
    Storage Temperature Store at 2-8°C
    Stability Stable under recommended storage conditions
    Synonyms Thioacetic acid S-propyl ester

    As an accredited S-N-Propyl Thioacetate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Amber glass bottle containing 100 grams of S-N-Propyl Thioacetate, sealed with a screw cap and labeled with hazard information.
    Shipping S-N-Propyl Thioacetate should be shipped in tightly sealed containers, protected from light and moisture. It must be packaged according to relevant hazardous materials regulations, such as DOT or IATA, and labeled appropriately. Store and ship at ambient temperature. Ensure secondary containment to prevent leaks during transportation. Handle with proper safety precautions.
    Storage S-N-Propyl Thioacetate should be stored in a tightly sealed container in a cool, dry, well-ventilated area, away from incompatible substances such as oxidizing agents. Protect the chemical from light, heat, and moisture. Ensure proper labeling, and avoid sources of ignition. Use appropriate chemical storage cabinets, and follow all relevant safety protocols for flammable and volatile organosulfur compounds.
    Application of S-N-Propyl Thioacetate

    Applications of S-N-Propyl Thioacetate in Industrial Manufacturing

    S-N-Propyl Thioacetate is a specialty organosulfur compound widely used as a key intermediate and character-impact agent in various industrial manufacturing sectors. As an original manufacturer, we deliver consistent quality and full traceability for integration into downstream production lines. The following sectors represent its established industrial applications, with compliance, use levels, downstream process details, and actual end product types clarified for B2B partners.

    1. Food Flavor Manufacturing

    S-N-Propyl Thioacetate provides authentic onion, garlic, and leek notes in food flavor creation. Leading flavor houses incorporate it during the compounding phase to achieve precise profiles for savory seasonings and processed foods. Our production supports strict traceability and batch reproducibility critical to food ingredient supply chains.

    Industry compliance standards

    • GB 2760 – China National Food Safety Standard for Uses of Food Additives
    • 21 CFR 172.515 – US FDA Flavoring Substances and Adjuvants
    • EU 1334/2008 – European Union Regulation on Flavourings and Food Ingredients with Flavouring Properties
    • ISO 22000/HACCP – Food Safety Management Systems

    Typical usage ratio

    • 0.2–15 ppm in end-flavor compounds, adjusted by volatile loss testing and organoleptic evaluation; dosage may be fine-tuned based on substrate, target aroma impact, and matrix sensitivity.

    Downstream process integration

    • Direct metering into flavor mixing tanks during compounding; often solubilized in a glycol or ethanol carrier to facilitate homogeneous distribution; heating steps are minimized post-addition to preserve sulfur note integrity.

    Final product types

    • Snack seasonings (potato chips, extruded snacks)
    • Meat analog flavorings and marinades
    • Ready-meal sauces and soup bases
    • Processed cheese flavor blends

    2. Aroma Chemical Synthesis

    This compound acts as a vital sulfur moiety donor in the synthesis of complex aroma chemicals, essential for perfumery and advanced fragrance intermediates. Downstream producers rely on consistent input quality for multi-step syntheses requiring precise sulfur atom transfer and selectivity during thioesterification or thiol-ene transformations.

    Industry compliance standards

    • IFRA Standards – International Fragrance Association guidelines
    • REACH (EC 1907/2006) – Substance Registration and Chemical Safety for Europe
    • ISO 9001 – Quality Management Systems for Aroma Ingredient Manufacturing

    Typical usage ratio

    • Usually 1–6 molar % relative to target molecule in synthesis batch; proportion adjusted by reaction stoichiometry and downstream purification potential.

    Downstream process integration

    • Introduced during the thioesterification or sulfur atom transfer stage, typically under controlled temperature and inert gas; progress monitored by HPLC or GC-MS analysis to confirm intermediate formation.

    Final product types

    • Thiophenic aroma intermediates
    • Sulfur-containing musk compounds
    • Fruity and savory fragrance bases
    • Complex alkylthioesters for high-impact perfumery

    3. Pharmaceutical Intermediate Production

    This material supports conceptual synthesis routes in the pharmaceutical sector where precise alkylthio group introduction is essential for bioactive compound development. API manufacturers specify its use for controlled build-up in stepwise chemical synthesis, and we supply GMP-acknowledged material with full batch documentation.

    Industry compliance standards

    • ICH Q7 – GMP for Active Pharmaceutical Ingredients
    • USP-NF/Ph. Eur. – Pharmacopeial Ingredient Purity Requirements
    • WHO GMP Guidelines
    • China Pharmacopoeia (ChP) For API Synthesis Precursors

    Typical usage ratio

    • Usage from 0.5–8 molar equivalents per synthesis step, defined by the alkylation or thioester step on process development; actual ratio determined by reaction optimization trials.

    Downstream process integration

    • Dosed into organic solvents for key alkylthio derivatization or thioester intermediate formation; downstream purification follows by chromatography or crystallization based on API impurity profile targets.

    Final product types

    • Thioester functionalized drug intermediates
    • Alkylthio derivatives for anti-infective and cardiovascular APIs
    • Bioactive small molecule precursors

    4. Crop Protection Synthesis

    Downstream agrochemical formulators use this compound for building the S-alkyl backbone in sulfur-enriched pesticide and fungicide active ingredients. Its known reactivity allows precise construction of thioester and thioamide structures, required for selective pesticidal activity and regulatory-compliant product profiles. Our continuous batches ensure low by-product levels critical for agricultural raw materials.

    Industry compliance standards

    • FAO/WHO Specifications for Agricultural Pesticides
    • ISO 9001 – Agrochemical Quality Systems
    • Chinese Ministry of Agriculture – Pesticide Registration Standards
    • REACH (EC 1907/2006) – Agrochemical Substance Authorization

    Typical usage ratio

    • Typically 1–4 molar equivalents, determined by target molecule synthesis route and dependent on side reaction suppression; validated by pilot batch testing.

    Downstream process integration

    • Used in heterocyclic thioesterification or S-alkylation reaction step; temperature and pH rigorously controlled to maximize yield; followed by neutralization, phase separation, and solid-liquid extraction for purity assurance.

    Final product types

    • Fungicide intermediates
    • Sulfur-based plant protection agents
    • Herbicide sulfur-functional group precursors
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    Competitive S-N-Propyl Thioacetate prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    S-N-Propyl Thioacetate: Expertise in Fine Chemical Synthesis

    Crafted by Chemists for Industry Use

    Years of hands-on synthesis have shaped our approach to manufacturing S-N-Propyl Thioacetate. Every batch comes off our reactors with the same care that we showed when creating our first kilogram. This thioester presents as a colorless to pale yellow liquid with a character easily identified from experience: it features a notable sulfur aroma and a chemical stability that assists both research and commercial sectors. Our production lines stay true to stringent process controls, providing consistent material so customers receive the same quality profile time after time.

    Distinctive Features and Material Integrity

    Many factories make flavors or intermediates with a focus on speed, but in our lab and plant, we emphasize precision. With S-N-Propyl Thioacetate, purity levels regularly exceed the requirements for food additive or pharmaceutical intermediate use. Our typical output surpasses 98% purity, measured by gas chromatography and confirmed through repeated laboratory checks. Trace impurities—mainly byproducts from synthesis—stay at a minimum because of distillation under reduced pressure, a step that removes more volatile and polar residues.

    We often hear from formulation teams who struggle with off-aromas or batch-to-batch variation from inferior grades purchased elsewhere. After seeing the output from resellers or contract facilities that prioritize price over quality, we built extra purification steps into our own workflow. This approach translates into improved shelf stability and clarity, along with an olfactory profile that matches natural ingredient benchmarks.

    Real-World Applications and End-User Value

    Flavor chemists recognize S-N-Propyl Thioacetate as a tool for constructing savory top notes, especially for onion, garlic, and cooked vegetable impressions. Its use isn’t limited to savory profiles; when used in measured amounts, it can develop nuance in cheese, meat, and a handful of tropical fruit essences. Beverage formulators and snack technicians appreciate the way this compound adapts to process conditions—holding up to heat in extrusion or pasteurization without rapid degradation.

    Outside of food science, research chemists value S-N-Propyl Thioacetate as a versatile intermediate. It acts as a sulfur donor in organic synthesis, and medicinal chemistry teams use it when designing new molecules that require thioester motifs. Our relationships with R&D teams in Europe and Asia have given us feedback about solvent compatibility and reactivity, which we’ve used to tweak downstream handling during production. This continuous process improvement means reduced waste and higher application yields for our end users.

    Why Manufacturers and Researchers Choose Our S-N-Propyl Thioacetate

    Over the last decade, we’ve seen the market flooded by trader lots, sometimes relabeled, sometimes poorly stored, often years old. These products seldom survive testing in high-end applications. By manufacturing every lot in-house, we have direct control over provenance, warehousing, and logistics. Analytical certificates match each batch and stay archived for client audits. Technical support comes straight from the chemists who make and handle the material, so questions about thermal stability, storage, or blending have a reliable answer.

    Long-term clients rely on us not just for supply but also for troubleshooting their own process challenges. When a major flavor house ran into problems with oxidation during snack coating, they asked our technical group for input. The answer came from data we’d collected on storage atmospheres: our S-N-Propyl Thioacetate, kept under argon and delivered in lined drums, retained its pungency and color longer than off-the-shelf imports.

    Specification and Testing: Chemist-Centric Standards

    Common requests involve details such as refractive index, density, and solubility in ethanol and vegetable oils. We provide actual batch values rather than relying on literature ranges. For every production run, our QC lab generates chromatograms and conducts spectroscopic tests—often FTIR and NMR—for structural verification. Clients in flavor and fragrance request additional sensory analysis, which our trained team carries out. Over time, this builds confidence in both the analytical data and the product’s ability to integrate into high-impact applications.

    Regulators in food and pharma demand detailed documentation. We back every drum and carboy up with full traceability, no matter the volume, and extend our traceability processes down to individual raw material lots. From a practical perspective, this means any question about odor deviation or trace contamination can be chased down in hours, not weeks. Flavors demand more than chemical purity—they depend on predictability, and our internal records help deliver just that.

    How S-N-Propyl Thioacetate Differs from Similar Sulfur Compounds

    Many users ask about the differences between S-N-Propyl Thioacetate and common thioacetates, like S-Methyl Thioacetate or S-Ethyl Thioacetate. The defining trait of our material lies in the propyl group’s influence on aroma—less sharp than methyl, more pronounced savory depth than ethyl. This gives chefs and chemists more control when building flavors that mimic slow-simmered onions or roasted vegetables. In food-grade production, background sweetness and reduction of off-notes come cleaner with the propyl variant.

    From a manufacturing standpoint, S-N-Propyl Thioacetate’s volatility and solubility line up closely with related compounds, but it offers improved flashpoint and a slower evaporation rate. These small tweaks make a big difference for processors working with open systems in hot environments. Fewer losses during winterization or deodorization lead to greater economy per kilogram imported or purchased.

    Batch Production: What Experience Has Taught Us

    Not every reaction proceeds the same, and the quirks of thioesterification come out over long production cycles. Standard lab conditions differ from a plant scale-up. Over the years, we’ve tuned catalyst loading, acid strength, and solvents for better product yield and easier phase separation. Careful washing and pH balancing help strip out unreacted starting materials, keeping each lot bright and fresh.

    Delivering thousands of kilos to the flavor and fragrance sector means seeing firsthand the difference that small changes in feedstock quality or process temperature can make. We’ve dealt with everything from unexpected humidity in the reagent warehouse to glass-lined reactor leaks, so our current workflow reflects both lab experience and hard-won practical knowledge. Every batch is checked by senior staff for odor, color, and stability, never left to junior teams who may miss subtle markers of degradation. For customers, this means less downtime investigating anomalies and greater trust in delivered material.

    Industry Trends and Demand Dynamics

    Demand for nuanced savory and allium-type flavors pushes innovation in thioester production. Artisanal food companies and global CPG brands both want authenticity in their ingredient decks, meaning fewer artificial notes and more resemblance to the cooking process. By using our S-N-Propyl Thioacetate, formulators achieve this authenticity, opening up clean-label formulations not just for snacks and seasonings but also meat alternatives and hybrid dairy products.

    Pharma and research labs pursue selectivity and reactivity, not just cost. The consistency of our thioacetate lets them plan synthesis runs that require precise sulfur transfer. Instead of hunting for lost yield or downtime due to poorly characterized side-products, chemists appreciate knowing they’re starting with exact, reproducible feedstock.

    We collaborate with flavor houses and intermediaries in the Middle East, South Asia, and North America. Each market brings its own regulatory systems and application preferences—some emphasize strict allergen control, others humidity resistance or halal certification. Our experience matching these needs builds technical trust and commercial loyalty.

    Sustainability and Safety Moving Forward

    Modern chemical manufacturing operates under increasing pressure to reduce both emissions and waste. We manage this at several points: starting with feedstock selection and moving through solvent reclamation and water treatment. Our plant reuses distilled overheads as pre-cleaning wash liquids for subsequent syntheses, and recycles spent solvent back into non-food industrial sections of our facility after careful testing. Our on-site treatment system eliminates more than 90% of organic residues before water reenters municipal treatment.

    Sulfur compounds, famously pungent, demand careful handling and containment. Each operation in our sequence—from raw material unloading to final drum filling—runs under closed-system protocols. Employees working in liquid transfer or cleaning wear full face and hand protection. We keep air monitoring sensors at multiple points, not just in the reactor area. Across the site, emergency procedures are regularly drilled. The result: no lost time incidents tied to S-N-Propyl Thioacetate in the last five years.

    Clients request detailed information about handling procedures, especially those building flavors for export markets. Our technical guides summarize PPE selection, storage temperatures, and secondary containment—drawn not from a generic template but from a decade of actual plant experience.

    Continuous Improvement with Direct Industry Feedback

    Feedback from users shapes our approach, from process tweaks to packaging upgrades. Early deliveries shipped in unlined steel drums sometimes absorbed odor and caused slight darkening. Switching to epoxy-lined and HDPE kegs reduced these risks, improving both storage lifetime and product profile. We track complaints and queries through a dedicated process, using each one to sharpen production and after-sales advice.

    One beverage producer reported temporary haziness in batches blended at higher temperature. Our technical group recreated their process, finding a minor interaction between thioacetate and certain preservative salts. Reviews of incoming raw material purity and collaborative troubleshooting minimized recurrence, highlighting how knowledge transfer can solve real-world bottlenecks.

    On the distribution side, we avoid over-warehousing, relying instead on tightly managed supply chains and established sea freight partners. This approach reduces time in storage and prevents quality drift tied to repeated drum opening, sunlight, or temperature swings. Clients who move product between several countries receive fresh, directly manufactured material with tracked transport conditions at each handoff.

    Commitment to Knowledge Sharing

    Not every manufacturer considers customer education part of their job. We do. We run internal seminars and targeted technical webinars on topics from thioester stability to sensory evaluation. Cross-training ensures that everyone—from shift chemist to account coordinator—understands not just what the product is but what it does in final use. This culture of education and transparency fosters stronger technical partnerships, often extending into co-development of new intermediates or ingredients.

    Industry standards change yearly, and client requirements shift in response to trends in flavor, health, and regulations. By staying closely tied to research journals, professional associations, and our own clients’ successes and failures, we help push both our product quality and the broader market forward.

    Looking Ahead

    S-N-Propyl Thioacetate remains an important material for the creation of layered, savory, and authentic flavors, as well as for selective reactivity in chemical synthesis. Our work as a manufacturer focuses on steady improvement in purity, reliability of supply, and technical collaboration. We remain committed to driving progress in both environmental stewardship and application support, so our partners always have access to the best material science can provide. As plant-based eating and global flavors surge, this thioester will have a prominent role, and our experience stands ready to support both seasoned experts and innovators exploring new applications.