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HS Code |
167401 |
| Chemical Name | (S)-(+)-Glycidyl Butyrate |
| Cas Number | 14228-71-0 |
| Molecular Formula | C7H12O3 |
| Molecular Weight | 144.17 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 85-86°C at 10 mmHg |
| Density | 1.037 g/cm3 at 25°C |
| Specific Rotation | +8° to +10° (neat) |
| Refractive Index | 1.424-1.428 at 20°C |
| Purity | Typically >98% |
| Storage Temperature | 2-8°C |
| Solubility | Soluble in most organic solvents |
As an accredited (S)-(+)-Glycidyl Butyrate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | (S)-(+)-Glycidyl Butyrate is supplied in a 25 mL amber glass bottle with a secure cap and tamper-evident seal. |
| Shipping | (S)-(+)-Glycidyl Butyrate is shipped in tightly sealed containers, protected from moisture and direct sunlight. It should be stored at controlled room temperature and transported according to standard regulations for organic chemicals. Proper labeling and documentation are provided to ensure safe handling during transit. Avoid contact with incompatible materials. |
| Storage | (S)-(+)-Glycidyl Butyrate should be stored in a tightly sealed container in a cool, dry, and well-ventilated area away from heat and sources of ignition. Protect from direct sunlight, moisture, and incompatible substances such as strong oxidizing agents. Store at room temperature, and avoid prolonged exposure to air. Properly label the container and follow all relevant safety and regulatory guidelines. |
Applications of (S)-(+)-Glycidyl Butyrate in Industrial ManufacturingOur facility supplies (S)-(+)-Glycidyl Butyrate to leading industrial manufacturers seeking high-purity, chiral glycidyl ester intermediates for specialized synthesis. This material plays a critical role where stereochemistry and reactivity impact formulation, downstream processing, and end-product performance. Below, we detail established application fields, with a focus on compliance standards, recommended dosage ranges, process integration points, and representative final products reported by our customers and audited against current regulatory frameworks. 1. Pharmaceutical Intermediate for Chiral Active IngredientsPharmaceutical manufacturers employ (S)-(+)-Glycidyl Butyrate as a chiral building block during the multi-step synthesis of select APIs, particularly where epoxy esters are essential to introduce S-configured centers via nucleophilic opening. Close monitoring of stereochemical integrity and absence of racemization is a core QC focus in this application. Material addition occurs in a controlled environment under GMP oversight, and analytical protocols validate trace purity throughout the process chain. Final APIs carry forward the stereochemical information provided by our raw material, necessitating strict adherence to global compliance requirements. Industry compliance standards
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2. Aroma and Flavor Ingredient ManufactureProducers in the food additive and aroma industries introduce this chiral ester as a key synthetic precursor in the formation of complex natural-identical flavor compounds. Controlled stereochemistry is critical in taste perception, so manufacturers use tight process controls and validated food-grade routes. The raw material can participate in both enzymatic and acid-catalyzed ring-opening to generate flavor molecules that pass regulatory and sensory panel requirements. Addition quantities are strictly regulated, ensuring batch traceability through to the flavored product’s market release. Industry compliance standards
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3. Specialty Epoxy Resin Modifier for Advanced CompositesAdvanced materials manufacturers utilize this raw material as a chain modifier or reactive diluent in high-performance epoxy formulations, where improved flexibility, toughening, and chirality-dependent performance are desired. This ester participates in curing reactions, influencing crosslink density and glass transition properties, with precise feed determined by target composite mechanics. Industrial safety and VOC regulations guide the formulation and use of the glycidyl ester, with downstream QC laboratories ensuring trace residual monomer levels and environmental compliance in cured articles. Industry compliance standards
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4. Chirally Pure Plasticizer and Additive for Biomedical PolymersProducers of medical-grade polymers and devices utilize (S)-(+)-Glycidyl Butyrate as an additive for chiral-dependent modification of polymer properties, such as flexibility, biocompatibility, and hydrophobic balance. This application requires extensive material traceability and validation of extractables and leachables to meet stringent healthcare market demands. The raw material enters at the monomer preparation or polymer compounding stage, with final extractable testing and bio-compatibility assays performed by downstream QA/QC teams before market release of molded or extruded goods. Industry compliance standards
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5. Fine Chemical Intermediate for Agrochemical SynthesisMajor agrochemical manufacturers employ this material as a stereoselective intermediate in the multi-step synthesis of select crop protection actives, particularly those demanding precise chiral control for environmental safety and regulatory registration. Maintaining enantiopurity and minimizing undesired residues is critical throughout process design, with solvent selection and purification steps influenced by target active requirements. Our supply agreements include custom QC documentation to support registration dossiers in major markets. Industry compliance standards
Typical usage ratio
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True advancements in specialty chemicals rarely come from the trading floor. They grow out of years behind the reactors, tuning the process and watching the smallest changes ripple outward to the final product. Our (S)-(+)-Glycidyl Butyrate stands on the back of that direct experience, where day-to-day lab work lines up with large-scale production, not just catalog promises. We produce this compound ourselves, building every batch alongside the chemists and engineers responsible for its purity and reliability. This perspective shapes everything from the technical choices in synthesis to the small steps that keep impurities out of every container.
For those of us making chiral building blocks like (S)-(+)-Glycidyl Butyrate, process matters as much as raw material grade. We operate our own reactors and keep tight control on enantioselectivity from the earliest step. Small errors in temperature or feedstock show up fast—not in the initial batch numbers, but weeks or months later as downstream processes run less cleanly. We have walked through more than enough customer process audits to know what gets checked—and which mistakes get magnified. Our material tracks its lineage, and our team can answer every step. That difference matters once you move past the bench and into the pilot plant.
This focus on hands-on production translates into consistent optical purity, reliable reactivity, and fewer headaches for end users. Anyone developing APIs, agrochemicals, or specialty resins using chiral intermediates has probably seen the difference between brochure chemistry and real-world, reproducible results. Consistent color, odor, and handling properties trace back to everyday discipline with glassware, solvents, and quality checks—not to faceless supply chains. In our operations, every process run, from synthesis to packaging, is carried out by staff familiar with its quirks and outcomes, and by teams who answer directly for any shift in material performance. That is the best way to keep production transparent and the science honest.
We supply (S)-(+)-Glycidyl Butyrate to companies focusing on enantioselective synthesis, performance coatings, and emerging biochemistry fields looking for reliable building blocks. Chemists working in drug discovery often rely on this material as a chiral synthon—a way to introduce both the epoxide and butyryl functional groups into target molecules. In practice, our customers integrate it into multistep syntheses where one part per thousand of the wrong enantiomer can wreck a downstream chiral resolution or raise regulatory headaches with racemization concerns. This is where in-house production gives us the edge. We know the pressure points for impurities, residual solvents, and racemization—and we cut the risks early rather than rely on supplier certificates or last-minute cleanup steps.
Outside pharma and life sciences, formulators use our (S)-(+)-Glycidyl Butyrate in specialty coatings, adhesives, and composite materials. The reactivity of the epoxide ring supplies a strong anchor for polymerization or crosslinking, and the chiral nature of the molecule introduces new stereochemical options in surface properties and resin performance. Large-scale industrial users benefit from tight specs on color, viscosity, and stability, but most look for relationships—knowing a real producer is available to troubleshoot issues as they come up. Over the years, we have seen new application areas open as synthetic biology, flavors, and advanced analytics markets look for chiral glycidyl esters. We partner directly with formulation scientists and researchers to tune synthesis conditions or explore alternate packaging to suit new needs—not just shipping a product and moving on.
Many product announcements quote model numbers and standard assays, but as the manufacturer, we put these figures into daily use. Our main-grade (S)-(+)-Glycidyl Butyrate comes off the line consistently with optical purity exceeding 98% ee, and GC purity at or above 99%. We use up-to-date analytical instrumentation not only because clients ask for proof, but because it saves us trouble investigating batch inconsistencies later on. In our field, percent enantiomeric excess is not a line on a COA—it's a factor that will make or break a customer's next round of synthesis. Our specifications carry weight because our batches match them: color, moisture content, d/l ratio, and detectable impurities all checked in-house. Our teams stay on standby to explain test results—their reputation tied to the quality as much as to the paperwork.
Our experience has shown that generic material sourced from a warehouse or trading agent rarely holds up over time, especially for applications needing scale-up or strict regulatory controls. As the original producer, we identify and control sources of batch-to-batch variation, which means lower risk for anyone relying on just-in-time manufacturing or complex formulation work. We have built quality systems as a living part of production, with staff empowered to halt lines, check intermediate product, or rerun a batch without waiting for external approval. Documentation from us flows from genuine batch results, not templated text. Over the years, this mix of technical discipline and direct accountability has solved issues before they turn into downstream delays or customer loss.
We are often challenged on price and availability by brokers or bulk chemical sites promising generic alternatives. Our answer is rooted in direct experience: material that cuts corners on production often comes with hidden traps—from low optical purity, to solvent residues, to regulatory gaps. We don’t outsource production or re-label third-party batches. Every sample and shipment comes directly out of facilities we operate with staff we have trained ourselves. This means our (S)-(+)-Glycidyl Butyrate holds to the same quality bars whether it is a ten-gram sample for an R&D bench or drum-scale production for full plant runs. In our business, switching suppliers for a few percent cost-saving rarely turns out well once the cost of failed syntheses, regulatory investigations, or missed customer deadlines is added in. Our clients return to us not just because of numbers on a certificate, but because our product performs batch after batch—with a known point of contact ready to answer problems in real time.
One sector that consistently finds risk in generic sources involves regulated pharmaceutical development. In direct conversations with QC and sourcing managers for both large and emerging biotech firms, we’ve heard the stories: high-purity claims that collapse under internal retesting, uncontrolled enantiomeric content, inconsistent solubility, or substituted solvents that gum up process lines. The issues rarely show up in the first small-scale run. The headaches start when the same nominal product gives erratic results at the 100-gram or multi-kilogram level, especially if the supplier lacks process documentation or transparency. As the direct manufacturer, we prioritize real traceability—batch sheets, test data, and operator logs are kept accessible, and customer audits are welcomed on site. This commitment earns repeat contracts, but also saves clients the much larger cost of late-stage process changes or regulatory findings.
For us, real value is built through years of consistent delivery, not through a few quick sales or by chasing the lowest pricing. The relationships built around (S)-(+)-Glycidyl Butyrate flow from helping customers adapt formulations, trouble-shoot analytic results, or modify packaging to avoid contamination or degradation in transport. Our technical teams field questions daily on process optimization—sharing lessons learned from our own facility trials and customer feedback loops. This direct feedback sharpens our ability to adapt process conditions or pivot production in response to shifts in supply chain, regulatory requirements, or customer end-uses. Over the years, it’s proven more sustainable than relying on trading margins or untraceable supply partners.
We have tracked the migration of (S)-(+)-Glycidyl Butyrate from a boutique chiral building block to broader use in new polymer systems and advanced synthetic biology. As the knowledge base for chiral esters expands, research groups lean most heavily on original manufacturers for specialty requests, high-volume demands, or nonstandard specs. This gives us a front-row view into emerging applications—and the ability to invest in new purification, isolation, or packaging technologies that make a real difference for advanced end-users. These investments feed back into our manufacturing, keeping us ahead of unexpected process or compliance bottlenecks down the line.
Compliance today goes well beyond standard certificates or simple audit trails. Especially as regulatory bodies tighten review of chiral intermediates in food, pharmaceutical, and specialty materials, supply chain transparency and process verification get tested. Because we make our (S)-(+)-Glycidyl Butyrate from start to finish—tracking raw materials, checking operator logs, and listing every purification step—our clients avoid last-minute questions and can prove origin, batch lot, and quality for all audited products. We’ve found this direct chain of custody to be especially important for clients preparing for regulatory submissions or scaling from pilot to commercial production. Instead of spending days tracing back imported drums through several middlemen, our partners see documented batch results and know our quality staff by name.
We also keep open channels with regulatory and standards organizations, adapting testing protocols or reporting methods to head off problems before they slow approval cycles. As both production chemists and on-site quality managers, we have the freedom to update SOPs, install new analytical instruments, or build additional documentation into the process flow as needs evolve. For some customers, this means the difference between a successful tech transfer and months lost to document tracing. Our teams take full responsibility for both the science and the paper trail—not as an extra, but as proof of work in every liter shipped.
Every bottle or drum of (S)-(+)-Glycidyl Butyrate carries the lessons of scale-up—diagrammed glassware, reactor temperature profiles, filtration challenges, and the occasional hiccup in yield or selectivity. As direct producers, we have a front-row seat for the quirks that turn up batch to batch: how humidity or a minor labware change shifts product color, what byproducts appear at longer hold times, and which solvent lots yield slight upticks in residuals. We have seen how process changes—reagent grade, purification steps, storage bulkheads—can take a batch from best-in-class to product recall risk. For us, improvement is driven by direct engagement with our own production lines, not theoretical best practices pulled from journals. We take each outcome back into process development, sometimes tuning the reaction order or batch size based on hard-won lessons from our own yields or purity numbers.
Our technical support for customers reflects this direct knowledge. Instead of issuing templated advice, we walk through practical troubleshooting based on our own reaction runs. Common questions—unexpected color shifts, filtration problems, crystallization on storage—tap straight into years of operator notes and QA data held in our own archive. This in-house cycle gives another layer of reliability for customers confident that their feedback doesn’t vanish into a generic support email. The result isn’t just higher technical value for (S)-(+)-Glycidyl Butyrate, but a stronger foundation whenever process scale-up or transfer challenges arrive.
Our experience as a direct producer shapes how we approach every part of the shipping and storage cycle. We have built packaging to resist moisture, light, and thermal swings, based on failures we have seen in uncontrolled supply chains. Early on, a few shipments taught us hard lessons about material degradation and cross-contamination; these events led to improvements in container selection and sealing protocols. Today, both small-volume and bulk packaging leave the facility with tamper-evident seals and clearly documented storage instructions developed from our own material stability studies. We keep samples from each batch in reserve, monitoring color and GC over months to inform both internal process changes and customer shelf-life planning.
For bulk industrial customers and research groups alike, prompt delivery and predictable inventory management build trust. Our logistics staff works closely with the production line, so that shipping leads do not weigh on quality or batch release times. For complex international shipments, we handle regulatory documentation and compatibility checks in-house, drawing on long-standing relationships with logistics firms and customs agencies familiar with specialty chemical shipments. The result cuts risk for all sides and aligns with the real-world operational needs of our customers—something not easily replicated by generic online suppliers or middlemen.
The chemical industry has felt market pressures and supply disruptions in recent years, but one fact remains clear: real trust flows from the producer’s ability to deliver both quality and accountability batch after batch. Our (S)-(+)-Glycidyl Butyrate embodies the lessons of direct manufacturing—no shortcuts, no relabeling, and transparent technical support shaped by our daily work in the plant. This foundation has helped our customers navigate everything from urgent process upsets to long-term scale-up programs, knowing that the same team making their product stands behind every shipment.
We have seen applications emerge and disappear, but consistent technical discipline makes the difference between fleeting market opportunities and long-term relationships. For new clients looking to move beyond generic sourcing, we welcome discussions centered on real science, not just price lists. For established partners, our open process and quality data stay available for audits, collaborations, and joint development. We help our clients get better results not because of what we promise, but because of what we prove—batch after batch, year after year. That’s how (S)-(+)-Glycidyl Butyrate from a direct manufacturer delivers more than just an entry in a chemical database—it brings real value and reliability rooted in original production expertise.