Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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(+)-Pulegone

    • Product Name (+)-Pulegone
    • Alias (R)-Pulegone
    • Einecs 216-924-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    744035

    Name (+)-Pulegone
    Cas Number 464-05-3
    Molecular Formula C10H16O
    Molar Mass 152.23 g/mol
    Appearance colorless to pale yellow liquid
    Odor minty, camphor-like
    Density 0.930 g/mL at 25°C
    Boiling Point 224°C (435°F)
    Refractive Index 1.476-1.480 at 20°C
    Flash Point 99°C (210°F)
    Solubility In Water insoluble
    Iupac Name (5R)-5-methyl-2-(1-methylethylidene)cyclohexanone

    As an accredited (+)-Pulegone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A clear glass bottle labeled "(+)-Pulegone, 25g," features safety symbols, supplier information, batch number, and tightly sealed screw cap.
    Shipping (+)-Pulegone is shipped in tightly sealed, chemical-resistant containers, compliant with safety regulations for flammable liquids. It must be stored away from heat and direct sunlight during transit. All packages are clearly labeled with hazard information, and shipping follows all local and international guidelines for transporting hazardous chemicals.
    Storage (+)-Pulegone should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area. Keep it away from sources of ignition, heat, oxidizing agents, and strong acids. Protect from sunlight and moisture. Store under inert gas if prolonged storage is needed, and clearly label the container. Ensure compliance with local chemical storage regulations.
    Application of (+)-Pulegone

    Applications of (+)-Pulegone in Industrial Manufacturing

    As a specialized manufacturer of advanced aroma compounds, we supply (+)-Pulegone for a range of demanding industrial sectors. Below, we detail distinct downstream application scenarios, operational frameworks, and compliance contexts supported by our expertise in chemical synthesis, process integration, and continuous quality control.

    1. Flavor Formulation for Food and Beverage Industries

    (+)-Pulegone provides a minty, refreshing top note widely used in flavor compounding for confectionery, oral care, and non-alcoholic beverages. Flavor chemists formulate it within controlled parameters to enhance cooling profiles and natural mint bases. Regulatory authorities stipulate specific inclusion levels and purity grades for food applications; our technical service team supports customers with analytical documentation and traceability from lot to finished batch.

    Industry compliance standards

    • Food Chemical Codex (FCC)
    • EU Regulation (EC) No 1334/2008 on Flavorings
    • U.S. FDA CFR Title 21 § 172.515 (Flavoring Substances and Adjuvants)
    • JECFA Acceptable Daily Intake (ADI) guidelines

    Typical usage ratio

    • 0.001%–0.05% in finished flavor formulations; actual ratio subject to flavor type and intended end-product, with lower levels in gum and oral rinses, higher end in candy and filled chocolates.

    Downstream process integration

    • Added during the compounding phase of liquid, emulsion, or powder flavor production.
    • Blended with essential oils and carriers prior to spray-drying or encapsulation.
    • Integrated with other aroma actives via mixers or ribbon blenders.

    Final product types

    • Hard candies and mint confectionery
    • Chewing gum and breath fresheners
    • Ready-to-drink beverages and syrups
    • Toothpaste and mouthwash flavors

    2. Fragrance Compounding in Perfume and Toiletry Manufacturing

    The unique minty, herbal characteristic of (+)-Pulegone enhances fragrance accords in fine perfumery and mass-market toiletry items. Fragrance houses use it for composition of masculine notes, colognes, and complex green bouquets. Extensive documentation of IFRA restrictions and analysis of sensitizing potential are prerequisites for formulation, especially for skin contact products.

    Industry compliance standards

    • IFRA Standards (International Fragrance Association)
    • Cosmetics Regulation (EC) No 1223/2009 (Europe)
    • California Safe Cosmetics Program (USA)
    • ISO 9235 (Aromatic Natural Raw Materials)

    Typical usage ratio

    • 0.005%–0.1% in fragrance oil concentrates; levels determined by application type (lower in skin care, higher in home care or air fresheners).

    Downstream process integration

    • Dosed in pre-blending of perfume oil bases with solvents and stabilizers.
    • Dispersed in ethanol or dipropylene glycol during modulated blending.
    • Used with aldehydes and terpenoids in top-note enhancement steps.

    Final product types

    • Eau de toilette and fine fragrances
    • Liquid soaps and foaming bath products
    • Deodorants and antiperspirants
    • Room deodorizers and scented candles

    3. Synthesis of Pharmaceutical Menthol Intermediates

    Hydrogenation of (+)-Pulegone is a key step in industrial menthol manufacture, including isomerization to specific menthol isomers for pharmaceutical-grade applications. The process requires validated input quality and batch accountability, with strict adherence to ICH Impurity Guidelines and API registration filings. Manufacturers demand high optical purity, consistent GC profiles, and validated impurity control from our supply batches.

    Industry compliance standards

    • USP-NF Monographs (Menthol, Pulegone)
    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • European Pharmacopoeia (Ph. Eur.) 10.0 Monographs
    • Drug Master File (DMF) registration requirements (US FDA/EMA)

    Typical usage ratio

    • Varies from 80%–96% by mass for menthol intermediate synthesis; precise ratio depends on catalytic system and process yield optimization.

    Downstream process integration

    • Fed to catalytic hydrogenation reactors under controlled conditions to yield menthone and menthol isomers.
    • Crude menthol separated via distillation and chiral resolution units.
    • Impurity tracing and analytical release performed post-hydrogenation.

    Final product types

    • Menthol for pharmaceutical, oral care, and medicinal balm products
    • Intermediate menthone and isomenthone used in further synthesis
    • Pharmacopoeia-grade essential oil components

    4. Agrochemical Formulation for Natural Insect Repellents

    (+)-Pulegone displays recognized insecticidal and insect-repelling properties, leading to its inclusion in certain natural pest management formulations. Agrochemical producers exploit its botanical origin and low environmental impact in compliance with regional pesticide and biocide regulations. Registration dossiers require detailed source tracing and eco-toxicological evaluation before downstream mixing and bottling.

    Industry compliance standards

    • Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH, Europe)
    • US EPA FIFRA Guidelines for Minimum-Risk Pesticide Ingredients (40 CFR 152.25(f))
    • OECD Guidelines for the Testing of Chemicals, Section 2 (Biocides)
    • ISO 9001 Quality Management Systems for production traceability

    Typical usage ratio

    • 0.2%–2.0% in emulsifiable concentrate or ready-to-use spray formulations; adjusted by type of target pest and overall formulation matrix compatibility.

    Downstream process integration

    • Mixed into surfactant blends or microemulsions during agrochemical premix preparation.
    • Stabilized with co-solvents and antioxidants before final packaging.
    • Quality control includes GC-MS fingerprinting of active levels in finished product.

    Final product types

    • Natural insect repellent sprays and lotions
    • Agricultural pest deterrent foliar sprays
    • Home and garden pest management products

    5. Industrial Solvent and Cleaning Agent Component

    The high solvency and characteristic odor profile enable applications of (+)-Pulegone in the formulation of industrial degreasing agents and specialty cleaning solutions, particularly where rapid evaporation and residue-free finish are required. Users in electronics and metalworking sectors select this raw material for controlled solvent systems, implementing strict workplace safety and permissible exposure thresholds defined by regional regulatory authorities.

    Industry compliance standards

    • OSHA Hazard Communication Standard (29 CFR 1910.1200, USA)
    • EU CLP Regulation (EC) No 1272/2008
    • REACH Safety Data Sheet (SDS) requirements
    • ASTM E1971 - Standard Guide for Screening Transportation Emergency Response Resources for Solvent Blends

    Typical usage ratio

    • 0.5%–5% by volume in cleaning agent formulations; adjusted based on required evaporation rate and compatibility with cleaning matrix and substrate.

    Downstream process integration

    • Blended with alkanes, alcohols, or oxygenated solvents at the final formulation stage.
    • Subject to filtration and stabilization before filling into bulk or unit packaging.
    • Batch QC involves detection of volatile residue and odor intensity scale.

    Final product types

    • Printed circuit board (PCB) cleaning agents
    • Metal part and tool degreasers
    • Specialty spray removers and industrial wipes

    6. Precursor for Aroma Chemicals and Fine Chemical Intermediates

    We supply (+)-Pulegone as a high-purity precursor for the commercial synthesis of several fine chemical derivatives, including lactones, diols, and complex ester compounds for the aroma and specialty chemicals sector. Our consistent batch documentation and impurity profiling support customers’ downstream oxidation, reduction, and cyclization processes in fully validated, REACH-registered workflows.

    Industry compliance standards

    • REACH Annex VII-X Registration for Intermediates
    • ISO 9001/14001 for chemical process manufacturing
    • Hazardous Substance Regulations (Globally Harmonized System, GHS)
    • Responsible Care principles for chemical manufacturing

    Typical usage ratio

    • Used as a key starting material (>85% mole ratio depending on end-product target); adjusted based on reaction mechanism and stoichiometry in batch or continuous production.

    Downstream process integration

    • Charged to reactor vessels in controlled amounts for ring-closure, hydration, or reduction steps.
    • Integrated with catalytic systems for selective oxidation or hydrogenation processing.
    • Intermediate finished goods assessed via NMR, GC-MS, and chiral HPLC.

    Final product types

    • γ-Valerolactone, piperitone, and structural isomers
    • Chiral alcohols and custom aroma aldehydes
    • Fine chemical intermediates for further pharmaceutical or agrochemical synthesis
    Free Quote

    Competitive (+)-Pulegone prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

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    Certification & Compliance
    More Introduction

    (+)-Pulegone: Direct from Manufacturer Insight

    What Sets Our (+)-Pulegone Apart

    Producing (+)-Pulegone starts with steady control at every stage, from raw material selection to purification. We source only clean, high-quality mint oils as feedstock, because impurities from lesser oils show up later in the process. At our site, technicians run fractional distillation under carefully managed temperatures and pressures, which lets us consistently reach a purity that chemical buyers expect. Every batch we put out hits over 98.0% (+)-enantiomer content, as confirmed by chiral GC. No assumptions—from tank sampling, to line clearance, checks run every shift, product always leaves the facility with a data-backed certificate of analysis. Clients in flavor, fragrance, and pharmaceutical fields count on specific lots to match specifications, so we track batch data all the way back to starting material shipments.

    Understanding (+)-Pulegone’s Unique Character

    Unlike synthetic blends that often carry a harsh note or traces of isomers, the product we supply keeps its fresh, pure mint aroma because of our feedstock and the distillation we use. This is no off-the-shelf commodity—(+)-Pulegone’s natural enantiomer gives a distinctly clean, cooling minty top note, and the subtle herbal body that blenders consistently praise. Terpenoid chemists have long recognized how this single enantiomer influences the sensory profile of mint flavors and how it fits into complex fragrance accords. Botanically sourced reference samples formed the model for our specification, so what comes out of our tanks looks and smells like nature intended, not a lab shortcut loaded with impurities.

    Specifications That Actually Matter in Manufacturing

    Buyers sometimes get frustrated reading out-of-context numbers on third-party data sheets. On our site, every drum and canister reflects what’s been physically measured, not just the certificate. That means minimum assay by GC gets checked every run, and odor gets the attention of multiple trained noses with years in mint oil distillation. Water content stays below 0.2% to protect storage stability; we use in-house Karl Fischer titration to confirm this. Typical refractive index values stay within a narrow window around 1.463—no guesswork. Density checks and specific rotation data let downstream synthesis and blending teams know exactly how their input behaves, with fewer surprises during scale-up.

    Real-World Usage and Direct Experience

    After decades making essential oil isolates for flavor and fragrance houses, it’s clear that (+)-Pulegone finds demand wherever authentic, natural mint profiles matter. Chewing gum, oral care, liqueurs, and top-shelf confections all rely on our product for sharp, clear mint character that doesn’t fade rapidly or clash with other terpenoids. Perfumers favor (+)-Pulegone as a core material in herbal, fougère, and cologne compositions because it provides a vivid fresh lift and a cool green backbone, integrating better than mint blends dominated by menthol or lesser isomer content. Analytical chemists formulating active pharmaceutical ingredients prefer our supply because the strict optical purity and low residual solvents let them move forward with registration files that withstand outside audit.

    We’ve worked alongside many of these teams in the lab and in production. A major confectionery client once struggled with batch-to-batch variation—one drum lending a bright minty lift, another numb with off-notes. The root cause tracked back to mixed-isomer supply from a reseller. After switching over to our (+)-enantiomer, consistency returned, and their product lines smoothed out during long production runs. This sort of troubleshooting happens regularly; makers learn not all mint is created equal. Our approach saves time and frustration, and the difference shows up in the finished profile.

    Comparisons to Other Pulegone Types

    Often buyers approach pulegone as a broad category without recognizing the performance differences between enantiomer-pure forms, racemic mixtures, or technical-quality blends. Racemic and industrial grades tend to be less expensive, yet they don’t deliver the distinct peppermint-fresh edge and often bring a heavy, slightly medicinal undertone. The (+)-enantiomer, by contrast, imparts a much more refined top note, which flavorists and perfumers prefer for high-purity consumer goods. Some secondary suppliers sell product with mixed plant sources or incomplete isomer separation, leading to inconsistent headspace aroma, and a harshness that stands out even in dilute blends or formulations.

    We’ve spent months on our purification process to avoid these pitfalls. Our pure (+)-Pulegone avoids the “muddy” character seen with technical or racemic samples and keeps the natural-style, crystalline mint note favored across markets. Applications in herbal liqueurs show off its distinct beverage performance, while racemic mixes fail to integrate without off-flavors showing even at low ppm. In topical personal care, particularly in balms and oils, our assessments with long-term clients proved that the pure version avoids skin warming, a feature not true for all grades. That subtlety comes from both isomer control and the handling of trace byproducts.

    Feedback Loops and Continuous Improvement

    While market demand cycles up and down, production quality has to remain steady. Direct feedback from bulk purchasers offers guidance no spreadsheet can match. One flavor client flagged a slight volatility loss during extended bottling runs, prompting us to invest in inert gas blanketing for storage drums. A major oral care maker requested a more concentrated packaging format to reduce handling losses, so we provided larger, sealed metal containers designed for automated lines. Every year brings a few more tweaks, whether it’s batch sizes, new packaging options, or trace-level contaminant analysis.

    On site, mid-career plant technicians keep logs describing conditions, downtime, and subtle notes about feedstock variation or odor changes. These notes drive process changes more reliably than outside audits ever could. Over the years, we’ve replaced heating elements, updated column controls, and cycled new glassware to cut contamination risk because every part in contact with pulegone leaves a trace. Small updates add up—the system we use now bears only passing resemblance to the rigs seen in old trade pamphlets. Workers here refuse to blend or “stretch” lots; all drums consistently reflect the harvests and runs that made them, every lot traceable with hand-written records to back up electronic logs.

    Supply Chain Transparency and Ethical Sourcing

    Ethical ingredient supply matters, not just as a slogan but as an everyday requirement. Sourcing (+)-Pulegone from botanical mint oils means keeping direct relationships with farmers and distillers. We regularly visit suppliers to monitor agricultural practices, confirm absence of unauthorized agrochemicals, and guard against adulteration at the field or still. Field teams help farmers maintain regenerative planting cycles, providing technical support to keep mint varietals healthy year after year. Distillation partners provide direct batch traceability and early batch samples, which lets us flag any harvest showing climatic stress or contamination before it enters our plant.

    Buyers and end-users often want proof that their inputs hold up under scrutiny when it comes to sustainable sourcing. Certification schemes alone aren’t enough; it takes local knowledge, ongoing investment, and willingness to cut ties with sources that can’t pass audit or drop below safety baselines. In recent years, growing awareness about trace contaminants in global mint oil prompted us to implement additional screening for heavy metals, pesticides, and plasticizers in both source oil and final purified material. All data is available for inspection, matching a trend where transparency is non-negotiable.

    Stability, Shelf Life, and Storage Advice Drawn from Experience

    Pure (+)-Pulegone holds its stability well in sealed drum and pail formats, provided it’s kept cool and away from sunlight. Unlike menthol or other monoterpenes that tend to oxidize quickly, our experience shows that (+)-Pulegone maintains aroma profile and chemical structure for well over a year when properly stored below 25°C, air sealed, and away from direct light. Our customers appreciate these real-world numbers, as no one wants volatile losses or profile drift just when a critical batch comes due. Direct shipments use inerted drums with tamper-evident seals; we instruct storage teams at receiving to maintain products away from alkaline cleaners, oxidizers, or high-temperature process areas.

    We’ve fielded inquiries where product failed shelf life elsewhere, usually because a reseller repacked or stored open drums under less strict settings. Once material absorbs water or oxidizes, off-odors develop that can’t be hidden by dilution or in-process blending. We back up every advice point with real shipment history and retested reference lots, never just reference to supplier claims. Staff chemists draw from both test data and over a decade’s worth of retained sample checks, giving a living record of year-to-year variation that buyers rarely see.

    Safety and Handling in the Eyes of Plant Workers

    Safe production and use of (+)-Pulegone centers on common sense, training, and clear communication. On our site, every technician gets hands-on safety routines: splash protection, chemical splash goggles, and well-ventilated work areas form the baseline. Management puts effort into labeling every line, valve, and storage zone, not only to protect our team but so that our clients know the precautions behind what they receive. Chemical reactivity stays low under standard handling, with fire risk only in the case of gross negligence with open flames. As part of our onboarding process, new staff spend time shadowing veterans, learning the telltale aroma of pure product versus degraded stock—a safer working environment comes from collective memory, not just binders of regulatory rules.

    Clients sometimes ask about workplace exposure limits, and we share our own air monitoring data alongside international guidance. While formal legal thresholds exist, experience shows that regular air exchange, localized ventilation, and careful transfer keep exposure well below any point of concern. Disposal of spent or off-spec material occurs via licensed channels, and staff receive regular refresher training on proper containment practices. The safety culture in our plant rises up from years on the job floor, supported by zero-injury targets and a shared belief that cutting corners never pays.

    Regulatory Connections and Market Expectations

    Global regulatory bodies keep a keen interest in how (+)-Pulegone is made, what’s in it, and where it ends up. Food, flavor, and fragrance regulations differ by region, so we stay up to date by sending samples for independent testing and maintaining documentation for all downstream applications. Flavors undergo extra scrutiny for toxicological profile; our technical team reviews each client’s intended use and advises on applicable use limits based on both international guidelines and direct experience with regulators. No two client profiles look the same—from oral care to fine fragrance, documentation expectations and batch traceability standards always move, but we stay ready to adapt thanks to direct experience in both audit prep and on-site reviews.

    Sometimes market shocks drive new attention to stability data or trace contaminant reporting—a recent regulatory notice about impurities in imported oils led us to expand our third-party testing frequency and depth. Clients exporting into multiple markets get full material dossiers, audit support, and access to formulated blend tracking extending over a decade. Collaboration with industry associations lets us keep ahead of new purity codes and emerging risk lists. We treat these not as bureaucratic hurdles but as part of the craft; the respect for detail keeps our output relevant in changing global markets.

    Shared Lessons: Buyers, Makers, and End Users

    Selling (+)-Pulegone only completes the cycle when end-users know exactly what they’re using, why quality matters, and how to handle it for the best result. Direct conversations with manufacturers, chemists, and even craftspeople on the shop floor teach us what matters most—predictable purity, clean supply, responsive documentation, and genuine transparency from source to drum. Buyers moving up from technical-grade blends to optical-purity (+)-Pulegone find immediate sensory gains in their products, fewer recipe tweaks, and better batch repeatability. Perfume houses credit our supply for improved stability and sillage in classic fragrance bases; flavorists speak to the improved shelf life and profile integrity across challenging regional markets.

    Difficulties sometimes crop up, rooted in handling mistakes, misunderstood chemical limits, or poor conduit information down the chain. We treat every issue as a chance to refine process and meet needs more directly. Staff chemists sometimes run impromptu webinars, walking clients through critical points of storage, blending, or analytical method validation. Seasoned buyers teach us which packaging, batch sizes, or documentation forms actually fit their process realities, so we stay responsive. Over time, the direct back-and-forth builds trust that stands when challenging harvests, regulatory shifts, or market volatility threaten less stable supply lines.

    Making (+)-Pulegone is more than filling a drum or hitting a specification—it’s a relationship built over decades, spanning agriculture, chemistry, and practical know-how. Every shipment, every batch, every feedback call sharpens what we deliver. Our commitment traces back to the field, through the distillation room, to the shipping dock, and into the hands of real users making real products worldwide.