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Phenylurea

    • Product Name Phenylurea
    • Alias Carbamide
    • Einecs 202-913-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    696192

    Chemical Name Phenylurea
    Molecular Formula C7H8N2O
    Molar Mass 136.15 g/mol
    Appearance White crystalline solid
    Melting Point 147-150°C
    Solubility In Water Slightly soluble
    Density 1.29 g/cm³
    Cas Number 103-01-5
    Odor Odorless
    Chemical Structure Aniline derivative with urea group
    Stability Stable under recommended storage conditions
    Ph Neutral to slightly basic (aqueous solution)
    Synonyms 1-Phenylurea, N-Phenylurea
    Uses Intermediate in chemical and pharmaceutical synthesis

    As an accredited Phenylurea factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Phenylurea is packaged in a 500-gram white HDPE bottle with a tightly sealed screw cap and clear hazard labeling.
    Shipping Phenylurea should be shipped in tightly sealed containers, protected from moisture and incompatible substances. It must be labeled according to regulatory requirements, and transported as a non-hazardous chemical unless mixed with hazardous materials. Packaging should prevent spills or leaks, and shipments should comply with local, national, and international transport regulations.
    Storage Phenylurea should be stored in a tightly sealed container in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers. Protect it from moisture and direct sunlight. Label the storage area and container clearly. Ensure that storage facilities comply with local, regional, and national regulations for chemical storage and handling.
    Application of Phenylurea

    Applications of Phenylurea in Industrial Manufacturing

    Phenylurea serves as a specialized intermediate and additive in several high-value industrial manufacturing processes, with established downstream usage in agrochemicals, pharmaceuticals, polymer modification, textile auxiliaries, and specialty coatings. As the direct manufacturer, we supply material that meets stringent compositional and consistency standards suited for these advanced applications. Below, we outline core application scenarios that leverage phenylurea's properties, each governed by distinct regulatory, formulation, and process requirements.

    1. Agrochemical Synthesis—Herbicide Intermediate

    Major agrochemical producers use phenylurea as a key precursor for substituted urea-type herbicides, notably in the production of phenylurea family weed control agents. The material’s purity and residual limits influence both synthesis efficiency and regulatory acceptance in finished pesticides. Our direct supply matches the required specification thresholds for mass-scale active ingredient production.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • Regulation (EC) No 1107/2009 (EU Plant Protection Products regulation)
    • US EPA Active Ingredient Tolerance Levels
    • ISO 9001:2015 certified quality management for agrochemical intermediates

    Typical usage ratio

    • 5–15% of total formulation batch based on target herbicide, adjusted for desired substitution pattern on the phenylurea core

    Downstream process integration

    • Direct introduction in early condensation steps of active ingredient synthesis during batch or semi-continuous process; pre-dissolved or in slurry form for optimal reactivity

    Final product types

    • Pre-emergence and post-emergence urea-based herbicides, such as diuron, linuron, and related crop protection agents

    2. Pharmaceutical Intermediate Production

    Innovator and generic pharmaceutical manufacturers employ phenylurea as a synthetic building block in the creation of certain active pharmaceutical ingredients (APIs), particularly for drugs containing the urea pharmacophore. Close control of impurity profiles and batch traceability remains critical due to regulatory scrutiny and downstream GMP documentation.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice Guidance for Active Pharmaceutical Ingredients
    • US Pharmacopeia and European Pharmacopeia monographs as required per end-product
    • FDA 21 CFR Part 211 (Current Good Manufacturing Practice for Finished Pharmaceuticals)
    • EU GMP Guidelines Parts I & II for active substance manufacturing

    Typical usage ratio

    • 2–10% depending on the reaction scale, stoichiometric requirements, and structure of the target API intermediate

    Downstream process integration

    • Used in the nucleophilic substitution or condensation phase, typically after base-catalyzed activation, in multi-step organic synthesis of urea-linked drug candidates

    Final product types

    • Pharmaceutical actives and intermediates for anti-hypertensive, anti-diabetic, and anti-inflammatory medications containing the phenylurea motif

    3. Polymer Modification—Chain Extender & Crosslinking Agent

    Industrial polymer manufacturers use phenylurea to control chain architecture and crosslink density during production of specialty polyurethanes and polyureas. The additive’s unique functional group introduces rigid linkages, enhancing mechanical properties and altering thermal performance—a requirement for engineered materials in demanding environments.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 on chemical safety for polymer additives
    • ISO 9001:2015 and ISO 14001:2015 for polymer processing facilities
    • ASTM D3574 (Flexible Cellular Materials—Urethane Foam Test Methods)
    • UL 94 (Flame classification of plastic materials)

    Typical usage ratio

    • 0.5–3 wt% relative to diisocyanate or polyol for chain extension; higher for targeted hard segment incorporation, depending on required flexibility and heat resistance

    Downstream process integration

    • Added during post-polymerization step or in-situ within reactor; formulated alongside isocyanate mixture under controlled temperature and moisture conditions to achieve homogeneous dispersion

    Final product types

    • High-performance polyurethane elastomers, rigid foams, specialty coatings for electrical and automotive components, and polyurea-based molded goods

    4. Textile Processing Auxiliaries—Anticrease Agent Synthesis

    Specialty textile chemical producers incorporate phenylurea in the manufacture of finishing agents designed to reduce creasing and improve durability in cellulosic and polyester fabrics. Its integration supports permanent press and wrinkle resistance when grafted or crosslinked with fiber substrates during textile finishing stages.

    Industry compliance standards

    • OEKO-TEX Standard 100 (Textile chemical safety)
    • ZDHC Manufacturing Restricted Substances List (MRSL)
    • ISO 30023:2010 (Textiles—Identification of fibre content)
    • REACH Annex XVII—Restriction on chemicals in textiles

    Typical usage ratio

    • 0.5–2% on the weight of fiber (owf), tailored to fabric construction and level of crease resistance required

    Downstream process integration

    • Applied in aqueous finishing bath during final pad-dry-cure processing stage, often with catalyst and formaldehyde donor compounds, to chemically bond with cellulosic chain or polyester surface

    Final product types

    • Wash-and-wear cotton textiles, durable press polyester/cotton blends, and industrial fabrics with enhanced crease recovery and dimensional stability

    5. Specialty Coatings—Corrosion Inhibitor Formulation

    Producers of industrial coatings utilize phenylurea as a functional corrosion inhibitor in anti-rust paint formulations. By forming stable complexes at the metal-coating interface, it interrupts electrochemical corrosion pathways, extending the protective lifespan of coated structures subjected to harsh service environments in plant, marine, and infrastructure assets.

    Industry compliance standards

    • ISO 12944 (Paints and varnishes—Corrosion protection of steel structures by protective paint systems)
    • SSPC Paint Application Standards
    • ASTM D610 (Evaluating Degree of Rusting on Painted Steel Surfaces)
    • RoHS compliance for heavy metal restrictions in formulated coatings

    Typical usage ratio

    • 0.2–1.5% by weight in coating formulation, with dosage evaluated by salt spray resistance and performance trials for target metal substrate

    Downstream process integration

    • Blended directly into primer or topcoat resin during formulation stage before milling and dispersion, ensuring uniform distribution of inhibitor functionality

    Final product types

    • Heavy-duty anti-corrosion primers, marine coatings, maintenance paint for industrial plants, and metal fabrication finishes
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    Certification & Compliance
    More Introduction

    Phenylurea: An Honest Insight from the Manufacturer’s Floor

    A Closer Look at Phenylurea in Real-World Manufacturing

    Every batch of Phenylurea that leaves our facility carries our years of experience in high-purity organic synthesis and a deep practical understanding of what the end-users look for. The material itself—known in the trade by its chemical structure as 1-phenylurea—begins as a simple crystalline solid, but the path from raw reactants to that finished product involves much more than following a formula. In daily operations, focus stays on maintaining strict quality benchmarks and addressing the needs of our partners in both agriculture and specialty chemical sectors.

    Model and Specifications: What We Actually Make

    Our Phenylurea comes standardized to a minimum assay of 99%. We monitor for impurities like aniline, moisture content, and by-products with rigorous in-process checks. Over the years, efficiency and batch uniformity have increased thanks to continuous process control—something that grows out of field experience rather than textbook procedures. Customers working in crop protection need confidence in the stability of the active substance, so we crystallize Phenylurea for controlled particle size distribution, often in the 0.1–0.5 mm range. No unnecessary additives or carriers find their way into these shipments. The white, nearly odorless crystals speak for themselves before any paperwork follows.

    Where Phenylurea Earns Its Keep

    Colleagues in agrochemical formulation rely on the unique molecular structure of Phenylurea. Urea derivatives bridge the gap between cost, soil compatibility, and plant uptake. Farmers do not always have the luxury to micro-manage soil amendments or herbicide effects, so robust performance in the field is critical. When used as an intermediate, Phenylurea enables production of several urea-based herbicides, each tailored for controlling broadleaf weeds without scorched earth effects on crops. In these applications, batch consistency and predictability make all the difference. Small variations in crystalline form or residual aniline content can shift how these various formulations perform under different climates and soil types.

    In recent years, Phenylurea also found a spot among building block chemicals for specialty resins and polymers. Polyurethanes, adhesives, and coatings sometimes need a degree of flexibility that only fine-tuned intermediates like ours can deliver. The advantage comes from tight control of the carbon-nitrogen bond during synthesis, allowing users in these downstream industries to avoid surprises during their own processing.

    Comparing Phenylurea to Other Urea Derivatives

    Every application tests both the substance and the skills of those who handle it. Phenylurea differs from straightforward urea or N,N’-disubstituted ureas not only because of the added phenyl group but because of what this means for both chemical and physical properties. Plain urea delivers nitrogen content for fertilizer, but Phenylurea brings selectivity for targeted agrochemicals. As manufacturers, the presence of the phenyl ring in the structure requires careful attention to synthesis routes, as improper handling of the precursor aniline results in unsafe or low-performing output. Some customers ask about cost differences compared to symmetrical diphenylurea or alkyl ureas. The premium reflects necessary investment in environmental and occupational safety controls—nothing theoretical about this when standing beside a reactor during a batch run.

    Our process does not rely on blanket approaches. Quality control teams track crystallinity, solubility, and chemical integrity at every key step, whether the product is destined for a local custom blender or a multinational crop science partner. This approach puts practical reliability ahead of novelty, as even minor composition differences can create bottlenecks or side-reactions later. Customers using urea-formaldehyde or other condensation products sometimes ask if they can substitute Phenylurea directly. In our experience, sulfonated or alkylated ureas react very differently under similar conditions, reinforcing the need for solid technical communication among all partners involved.

    Why Reliable Phenylurea Matters in Practice

    Our research and production teams work closely because we hear about missteps in the field when a competitor’s poorly finished product hits the market. Slight drops in purity cause unwanted side-effects in formulation. For instance, unreacted aniline traces above 0.05% harm both final product safety and worker health during blending. Years ago, issues with storage stability led to hard lessons: even trace moisture increases risk for caking, making downstream processes unpredictable. These are the problems that a manufacturer wrestles with head-on, and they come from practical problem-solving, not from vendor PowerPoints.

    Unlike direct-fertilizer bulk urea, Phenylurea primarily plays an upstream role—feeding more complex synthesis chains. Its value multiplies as it passes from one skilled hand to the next. Quality at every stage becomes cumulative; any lapse early on stays with the product until the end.

    Manufacturing Insights: What Experience Teaches

    Day after day, the familiar scent of phenyl reagents and the hum of reactors create an environment where shortcuts prove costly. We operate under a framework drawn from both international and local standards for handling aromatic amines and urea derivatives. These standards do not just fill manuals—they guide our choices of process temperature, pressure, and waste handling procedures. Our operators track temperature and pH every shift, logging minute-by-minute data. This discipline grew out of direct feedback from partner labs, who flagged solubility deviations that were traced back to cooling rates or pH fluctuations during final precipitation.

    Family-run operations and global conglomerates both care about safety. For us, on-site safety goes beyond posters on the wall; it means batch samples are not just labeled, but actually checked for off-spec odors, particle flow, and color. Stories circulate within the team about missed anomalies, so a culture of double-checking thrives. We maintain on-site containment so no untreated runoff or dust can leave the facility, a step prompted by both regulatory guidance and practical respect for our team and neighbors. Our environmental investments in condensate recovery and closed-loop solvent handling grew straight out of real incidents, not abstract risk models.

    End-Use Perspectives: What Happens Down the Supply Chain

    Feedback from customers does not fade into a report archive. It leads us to adapt source material selection, reactor setups, and even packaging formats as needed. One major herbicide blender once raised an issue with anti-caking agent residues introduced by a trader. This changed our approach entirely, and we now guarantee additive-free output. When a specialty resin producer needed a shift from multi-ton bulk sacks to controlled 25-kg drums, rapid adaptation meant shipment delays did not set back their planned production. These experiences define how we see our relationship with end-users. Instead of shipping a product and moving on, the learning circle continues. Our technical team runs post-formulation checks on request for key partners, helping to ensure the final performance matches their development needs.

    Years spent working inside the industry reinforce one core lesson: a dependable chemical partner enables innovation downstream. If a formulation chemist can trust each batch will perform identically, that frees up resources for creative development—whether aiming for a more selective herbicide or a specialty polymer with novel properties. Missteps cost everyone, so high reliability remains non-negotiable. In this sector, loyalty grows through shared ownership of both success and setbacks.

    Addressing Challenges: What Real Solutions Look Like

    Supply chain bumps test even the most robust operations. Sourcing aniline, a core precursor to Phenylurea, presents logistical headaches every year, from pricing swings to transportation bottlenecks. As a manufacturer, securing long-term contracts with suppliers helps, but we also invest in near-term buffer stocks to ride out volatility. Local partnerships with rail and trucking outfits grew from experience—containers abandoned at the port can spoil a quarter’s work. Direct communication with suppliers shortens response time when the unexpected occurs. When incoming feedstock quality dipped, we rerouted procurement channels and adjusted purification stages mid-stream, not after customer complaints surfaced.

    Another challenge revolves around regulatory compliance. Inventory management evolved as jurisdictions ask for ever more detailed traceability in chemical handling. Our on-site teams track every kilogram, down to the drum, using a digital backbone that interfaces with both our own labs and external inspectors. Experience teaches that no one can afford to gamble on “good enough.” Fines or delivery bans carry real costs, and so do reputational dents from being slow to adapt. Our investment in traceability boosts confidence, but also reveals new opportunities for process improvement as data accumulates.

    Maintaining worker safety and environmental stewardship goes hand in hand with chemical quality. Regular training and genuine employee buy-in, more than just compliance for compliance’s sake, have driven incidents steadily down. Near misses are openly discussed and lead to targeted upgrades—whether updating dust extraction or improving storage bin design to reduce manual handling risks. These incremental adjustments come from staff insights, many of whom have spent decades in this exact facility.

    What Makes This Phenylurea Unique

    The strengths of our Phenylurea rest not on marketing claims, but on a well-documented track record. Partner audits show batch-to-batch consistency over years, enabling formulators to spend less time troubleshooting and more time delivering results for growers and industrial users. Custom crystallization setups, modular reaction trains, and locally sourced reactants create a short, resilient supply network less vulnerable to global snags. Our production teams are on-site and hands-on, ensuring nothing leaves without full lab clearance, physical inspection, and correct documentation.

    We welcome technical queries from partners—the best process improvements usually start with unexpected customer questions. Decades spent in close collaboration with agrochemical blenders and resin houses shaped our approach to continuous process adaptation. With regulatory landscapes changing each year, having a manufacturing partner who has already walked through the maze of compliance requirements makes the difference. Ultimately, we tie our name to every drum that rolls off the line, backed by the same team who will answer the phone if any issues ever arise.

    Industry Changes: Learning on the Job and Responding Quickly

    Shifts in environmental policy brought new scrutiny to uses of aromatic compounds and urea derivatives. Our process engineers follow these developments as closely as anyone, but adaptation stays rooted in what actually works on the floor, not in theory. Over the years, we have upgraded solvent recovery, reduced dust emissions, and adopted energy-efficient refrigeration—all solutions trialed under real manufacturing conditions. Waste reduction and resource recycling now affect the bottom line as much as it shapes corporate reputation. Insights from these changes filter back across all product lines, not just Phenylurea.

    Traceability and digitalization seem like buzzwords in trade journals but show true value on busy days. By embedding barcoding and real-time data acquisition, each lot of Phenylurea links to a digital record covering origin, synthesis, inspection, and shipment details. If a formulation question arises months later, we track every relevant production variable in minutes. Manufacturing teams recommend further tweaks based on this historical data, so adaptation does not mean disruption. Our field technicians routinely visit customer facilities, benchmarking actual product use and reporting findings directly to our in-house improvement committee.

    Recent collaborations with universities and public research bodies introduced new methods for eliminating trace impurities. Sometimes, real-world constraints require compromise—absolute zero tolerance is impossible with multi-ton chemistry. Knowing the material inside-out allows realistic target setting, and feedback loops close quickly thanks to our company culture of openness. Partnering with third parties for independent analysis, both in-house and at customer sites, pushes continual improvement. This candid cooperation grows from years in the trenches, not just business contracts.

    Dealing with Counterfeiting and Supply Chain Integrity

    Colleagues across the industry know the headaches caused by counterfeit or substandard product entering the market. The risk does not end with logistics; spot checks routinely catch mis-labeled or adulterated material—often with direct consequences for product safety. There have been cases where off-spec batches from offshore resellers disrupt complex production lines that depend on predictable performance. Our strategy has been to remain completely transparent about our source materials and in-house processing, invite audits, and share third-party analysis certificates up front. This approach lets partners buy on trust rather than only on price.

    In one memorable year, a client in Eastern Europe called to report failed analytical specs. On-site testing eventually traced the issue to containers tampered with in transit, prompting immediate upgrades to our packaging security. Documented chain-of-custody measures, anti-tamper seals, and regular review of logistics partners now standardize our response. Lessons learned never fade; instead, they shape daily routines from warehouse through distribution.

    Experience in Global and Local Markets

    Serving both regional and global needs shapes how we approach product adaptation. International regulations do not always align, so our compliance officers help customers map routes through this maze. An agricultural researcher in Latin America may face limits on allowable impurities that do not match those in Europe. We customize product handling and documentation in response, providing just the data needed to clear import/export hurdles without generating paperwork mountains. Conversations with customers in widely different climates—monsoons in South Asia, arid fields in North Africa, cold storage in northern Europe—influence how we adapt both product characteristics and packaging.

    On the local front, everything comes down to relationships. Regular contact with repeat buyers keeps us ahead of shifts in planting seasons or changes in regional regulations. Smaller specialty users value batch flexibility, which is why we run pilot-scale synthesis alongside regular production. Response time matters as much as price; in a pinch, rapid turnarounds win more lasting loyalty than transactional savings.

    The Role of Transparency and Knowledge Sharing

    No manufacturer stands alone. Years in the field taught us that knowledge sharing strengthens the whole supply network. Open forums with peer manufacturers, technical societies, and end-users lead to shared standards for safe and effective chemical use. Our R&D team presents findings on process innovation, but just as often, they listen and learn from others’ struggles with logistics, formulation, or lab analysis. Internal workshops on new synthesis techniques, tailings treatment, or crystallization efficiency filter findings to each level of staff.

    Investing in external audits and jointly developing best practices with industry partners secures not only our own compliance but helps raise broader standards. This practical transparency finds its value at scale, where good chemistry depends on open dialogue rather than top-down mandates.

    Where We See the Future of Phenylurea

    Opportunities for improvement stay ever-present. The next generation of urea-based agrochemicals will demand both higher purity and more exacting physical controls, in part due to regulatory tightening and in part due to environmental pressures. Manufacturing teams stand ready to trial new purification systems, solvent choices, and waste minimization approaches based on actual field experience, not market forecasts. Technical partnerships with both long-standing and new customers supply the momentum for steady evolution.

    Chemical manufacturing never stands still. Navigating real, practical challenges across sourcing, handling, and distributing Phenylurea builds genuine resilience. On the production floor, the lessons of the past drive today’s actions, and today’s innovations lay the groundwork for tomorrow’s standards. In this way, each shipment of Phenylurea represents not just a reaction completed or a drum filled, but a continuing story of adaptation, diligence, and real-world expertise.