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Phenylsuccinic Anhydride

    • Product Name Phenylsuccinic Anhydride
    • Alias 3-Phenyloxolane-2,5-dione
    • Einecs 217-063-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    959962

    Chemicalname Phenylsuccinic Anhydride
    Casnumber 638-16-4
    Molecularformula C10H6O3
    Molecularweight 174.15 g/mol
    Appearance White to off-white crystalline powder
    Meltingpoint 62-65°C
    Boilingpoint 355°C
    Solubility Insoluble in water, soluble in organic solvents
    Density 1.298 g/cm3
    Refractiveindex 1.620
    Storageconditions Store in a cool, dry place, tightly closed container
    Hazardclass Irritant
    Synonyms Benzylsuccinic anhydride

    As an accredited Phenylsuccinic Anhydride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Phenylsuccinic Anhydride, 100g: Supplied in a sealed amber glass bottle with tamper-evident cap and detailed hazard labeling for laboratory use.
    Shipping Phenylsuccinic Anhydride should be shipped in tightly sealed, corrosion-resistant containers, protected from moisture and incompatible substances. Transport under cool, dry conditions, following local, national, and international regulations for hazardous goods. Label packages clearly with hazard warnings and ensure documentation accompanies the shipment for safe handling and emergency procedures.
    Storage Phenylsuccinic anhydride should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from moisture and incompatible substances such as strong bases and oxidizing agents. Protect it from light and sources of ignition. Always follow safety protocols and store in a designated chemical storage area, clearly labeled, and out of reach of unauthorized personnel.
    Application of Phenylsuccinic Anhydride

    Applications of Phenylsuccinic Anhydride in Industrial Manufacturing

    As a direct manufacturer with full control over production and quality assurance, we supply phenylsuccinic anhydride to essential industrial segments where its functionalities address precise technical needs at scale. Below, we detail the most mature and validated downstream fields where our material delivers defined performance in formulation, batch synthesis, and finished product consistency.

    1. Curing Agent for Epoxy Resins in Advanced Composites

    Composite material producers employ phenylsuccinic anhydride as a specialized curing agent, leveraging its controlled reactivity to achieve targeted cross-link density in high-performance laminates. The compound finds primary use in fabricating aerospace, wind energy, and electronics-grade composites where mechanical strength, electrical insulation, and dimensional stability at elevated temperatures are mandatory. Formulators select dosage based on resin viscosity and processing window, tuning hardening kinetics for press, vacuum, or autoclave cure cycles. Our engagement includes technical guidance on raw material introduction post-epoxy prepolymerization and routine support for composite customers demanding matrix uniformity and long-term aging resistance.

    Industry compliance standards

    • REACH regulation (EC) No 1907/2006
    • RoHS Directive 2011/65/EU
    • EN 60243-1: Electrical strength of insulating materials
    • ASTM D1651: Curing agent evaluation for epoxy resins

    Typical usage ratio

    • Ranges from 8–18 parts per 100 parts epoxy resin by weight, adjusted in response to desired cross-link level, working time, and post-cure requirements.

    Downstream process integration

    • Added after primary mixing of epoxy resin and filler; introduced during compounding for viscosity control; batch processed under nitrogen or vacuum for air entrapment minimization.

    Final product types

    • Prepreg carbon/glass fiber laminates
    • Rigid printed circuit board substrates (FR-4 equivalents)
    • Aerospace interior sandwich panels
    • Electrical insulation structures for high-voltage systems

    2. Chain-Terminator in Polyester Polyol Synthesis for Polyurethane Systems

    Producers of polyester polyols utilize phenylsuccinic anhydride as a precise chain-terminating agent, unique in its ability to introduce controlled aromaticity into the polyol backbone. This functional group addition enhances thermal resistance and imparts desirable hardness and solvent resistance to subsequent polyurethane foams, adhesives, and coatings. Its deployment occurs in closed-reactor esterification processes, monitored via in-process acid number titrations, contributing to batch reproducibility and improving end-use properties for demanding construction, automotive, and appliance applications.

    Industry compliance standards

    • ISO 9001:2015 Quality Management System
    • ISO 17025:2017 Laboratory process validation
    • UL 94 Flame Retardancy for finished PU systems
    • Directive 2002/95/EC on the Restriction of Hazardous Substances

    Typical usage ratio

    • Typically 0.5–2.5 mol% relative to total glycol feed; final level set by target polyol functionality and desired aromatic incorporation.

    Downstream process integration

    • Charged into reactor after base diol charging and pre-heating; controlled addition ensures full anhydride conversion; post-reaction vacuum stripping to remove unreacted material prior to polyol packaging.

    Final product types

    • Structural rigid polyurethane foams (insulation panels, appliance foams)
    • Casting polyurethanes for abrasion-resistant parts
    • High-gloss architectural coatings
    • Two-component polyurethane adhesives

    3. Intermediate for Non-Steroidal Anti-Inflammatory Drug (NSAID) Synthesis

    Bulk pharmaceutical ingredient manufacturers apply phenylsuccinic anhydride as a core intermediate in multi-step chemical syntheses of select non-steroidal anti-inflammatory drugs. Its defined aromatic-succinic structure allows for predictable ring-opening reactions, serving as a precursor for APIs like phenylbutazone and related derivatives. Manufacturing batches operate under GMPs with full traceability, ensuring that impurity profiles and residual anhydride levels comply with international pharmacopeial guidelines. The material’s consistent reactivity directly impacts downstream API yield and purity, critical for reliable patient outcomes in the pharmaceutical value chain.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) for Active Pharmaceutical Ingredients
    • Ph. Eur. (European Pharmacopoeia)
    • USP (United States Pharmacopeia)
    • 21 CFR Part 210–211 cGMP for finished pharmaceuticals

    Typical usage ratio

    • Stoichiometric to limiting reactant; typical pharmaceutical-scale reactions use equimolar to slightly excess quantities, with adjustment per targeted conversion and downstream purification protocol.

    Downstream process integration

    • Introduced in controlled-stage syntheses, generally via direct mixing with Grignard reagents or amine hydrochlorides; excess removed by extraction for minimized carryover to API stage.

    Final product types

    • Phenylbutazone API
    • Related NSAID precursor intermediates
    • Specialty fine chemical building blocks for custom synthesis houses

    4. Modifier for Alkyd and Polyester Resin Production

    Industrial resin manufacturers incorporate phenylsuccinic anhydride as a chain modifier in alkyd and polyester resin formulations, seeking improved hydrophobicity, gloss retention, and surface hardness in architectural and industrial coatings. Its introduction alters the branching and molecular weight of the polymer network, providing controlled balance between hardness and flexibility. The material integrates at the polycondensation stage, where its unique aromatic succinic group ensures reproducible modification of functional group distribution. Production closely tracks acid value and viscosity, with application-driven process adaptation for high-solids or low-VOC resin systems.

    Industry compliance standards

    • ISO 12944 Corrosion Protection of Steel Structures by Protective Paint Systems
    • EN 927 Exterior Paints and Varnishes
    • ASTM D5895 Drying or Curing During Film Formation of Organic Coatings
    • National VOC emission standards for coatings

    Typical usage ratio

    • Used at 1–4 wt% of total acid content, with optimization per target film hardness, gloss, and flexibility.

    Downstream process integration

    • Charged with fatty acids and polyols at start of heat-up; in situ monitoring of polycondensation; resin sampled for molecular weight and branching index.

    Final product types

    • High-gloss alkyd automotive enamels
    • Solvent-based industrial maintenance coatings
    • Outdoor architectural paints
    • Wood finishing and furniture lacquers

    5. Hydrophobicity Enhancer in Water-Repellent Concrete Additives

    Construction chemical formulators select phenylsuccinic anhydride as a functional additive to impart long-term hydrophobization in concrete treatments. The compound enables the synthesis of siloxane-polycarboxylate hybrids and other surface-reactive agents that efficiently mitigate water ingress and efflorescence in exposed concrete. During additive batch processing, our technical team supports precise dosing according to mix design, ambient cure conditions, and regulatory limits. Finished additives provide water repellency without compromising vapor permeability, meeting strict standards for civil infrastructure durability.

    Industry compliance standards

    • EN 1504-2: Products and systems for the protection and repair of concrete structures
    • ASTM C642 Absorption and voids in hardened concrete
    • REACH regulation (EC) No 1907/2006
    • DIN 1048 Water penetration test

    Typical usage ratio

    • 0.2–0.8 wt% by weight of total additive concentrate; dosage refined by surface area, concrete composition, and required resistance level.

    Downstream process integration

    • Pre-reacted with silanes/siloxanes in reactor stage; post-blended in water-soluble or emulsifiable concentrates before formulation shipping to ready-mix or prefab concrete plants.

    Final product types

    • Water-repellent admixtures for ready-mix concrete
    • Surface impregnation treatments for bridges and tunnels
    • Protective coatings for façade stonework and precast panels

    6. Crosslink Modifier in Specialty Polyimide Film Production

    Advanced electronics manufacturers employ phenylsuccinic anhydride during the synthesis of specialty polyimide precursors, using its unique ring structure to modulate chain flexibility and thermal performance in high-temperature films. Its measured incorporation shapes final film properties, such as dielectric loss, heat resistance, and mechanical strength, which are essential for applications like FPCs (flexible printed circuits) and electrical insulation tapes. Integration occurs at polyamic acid synthesis, under precisely controlled stoichiometry and reaction temperature profiles, monitored by HPLC and FTIR to confirm structural incorporation.

    Industry compliance standards

    • IPC-4202A Flexible Base Dielectric Materials for Use in Flexible Printed Circuits
    • UL 746B Polymeric Materials - Long Term Property Evaluations
    • IEC 60216 Electrical Insulating Materials - Thermal Endurance
    • ISO 9001:2015 Quality Management in Polyimide Film Production

    Typical usage ratio

    • Between 1 and 6 mole percent relative to dianhydride comonomers; selection depends on targeted flexibility and thermostability of the final film.

    Downstream process integration

    • Added during initial mixing with diamines and main dianhydrides; reacts in situ with aminated monomers; followed by film casting and imidization at elevated temperature.

    Final product types

    • Flexible circuit films (FPCs)
    • High-temperature insulation tapes
    • Specialty dielectric barrier layers for electronics
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    Certification & Compliance
    More Introduction

    Phenylsuccinic Anhydride: A Key Ingredient Shaped by Experience

    An Introduction Based on Real Production

    The chemical industry never stops asking for reliable compounds that serve more than a single role, and Phenylsuccinic Anhydride answers this call in real laboratory and plant environments every day. After years of running batch and continuous processes for its synthesis, we have learned how crucial consistency and chemical purity prove for downstream performance. Let’s talk about what sets this product apart—not just formula on a page, but practical knowledge earned through real-world application.

    The Model That Works in the Factory

    Our production of Phenylsuccinic Anhydride sticks closely to a process that delivers high assay and functional usability. We focus on a model that controls reaction temperature, minimizes impurities at each phase, and keeps color indices low. Typical output hovers above 99 percent purity by HPLC assessment. Years of hands-on extraction, crystallization, and drying work have shown how trace by-products cause headaches in polymerization or pharmaceutical synthesis, so each lot undergoes close inspection. Stronger batch control cuts the risk of contamination, and cooling profiles during crystallization are set by operators who have watched how flow and temperature changes affect end results. The lessons learned here go straight into every packaged drum or sack.

    How Specifications Influence Real-World Performance

    We start from the recognized benchmarks: white to off-white crystals, melting points sitting near 120 degrees Celsius, acid number falling in the tight range that chemists expect. That’s just a baseline. Consistent melting behavior means less trouble with variable reactivity during panel or resin formulations. High residual solvent means nothing but wasted time during user drying—so our product comes in well below the detectable range on most common solvent tests. Rigorous moisture control keeps hydrolysis at bay, vital for storage and end-user stability. All these numbers stem from repeated adjustment, batch tracking, and off-spec recall implemented by the production and QA team. Each figure connects directly to a customer’s line speed or finished goods shelf life.

    What Phenylsuccinic Anhydride Does on the Plant Floor

    Users choose Phenylsuccinic Anhydride mostly for its solid anhydride group that’s reactive in a variety of syntheses. In the world of specialty resins, it modifies polyesters and alkyds, building flexibility and thermal stability into coatings that live out in the sun or in chemical environments for years. In pharmaceutical API production, it adds value by offering a reliable starting point for certain succinimide and amide applications. More than a few custom projects came to us for tweaks in anhydride purity or a different particle size; it taught us that some end-users grind or dissolve the product directly. Even small deltas in particle size curve or flowability can upset a blending process. That’s why run-to-run consistency makes sense—not just some notion of ‘uniformity,’ but hours of hands-on blending and reactivity trials.

    How It Differs from The Other Succinic Anhydrides

    Many users ask what sets phenyl-substituted succinic anhydride apart from lesser-known options like maleic or plain succinic anhydride. The phenyl group isn’t just another label—adding that ring structure changes more than reactivity. In polyester modification, you see a real rise in aromatic content, and that can transfer to UV stability and shelf life. Plain succinic anhydride won’t build these characteristics into a polymer backbone. Our R&D chemists have had customers request trials with both, and the final resin properties diverge sharply. Maleic anhydride, with its double bond, gives other possibilities—more suited for addition rather than the robust, ring-based modifications that come from phenylsuccinic chemistry. The density, melt profile, and even the smell that lingers in production are not the same. This all plays out in actual reactor and extruder performance, not just textbook tables.

    Toughness and Handling in Real Manufacturing

    Every batch has faced the challenges of packing, storage, and transfer under varying humidity and temperature—conditions not found in the comfort of the lab. Experience shows that improper sealing during rainy months can bring slow hydrolysis, changing acid number and triggering clumping long before expiry. We maintain environmental controls in warehousing and encourage users to minimize open-air exposure when charging solids into reactors. Several coatings and compressed air systems run with dry transfer lines for just this reason. Protective gear and enclosed handling reduce loss from dust or fine material that otherwise escapes during pneumatic transfer. In scaling up from kilo lab to full production, we have revised standard operating procedures to keep each lot true to spec, time after time.

    Sustainability and Waste Strategies

    There’s a growing demand for more responsible chemistry, and the story of Phenylsuccinic Anhydride has not skipped this shift. We see the waste streams, and we’ve had to update our recovery processes—cutting down on organic solvent use and capturing off-gases for reuse. Part of our production improvement comes from reducing the energy demands in dehydration reactions, moving towards continuous processing instead of batch where feasible. It’s not marketing fluff; if you stand by a reactor, you see how solvent recovery and careful distillation reduce both air emissions and disposal costs. Lifecycle management goes beyond the gate, and smart users look at by-product streams for potential inputs in other sectors. Ultimately, less waste means safer work environments, better compliance, and lower operating costs.

    Safety and Real-World Hazards

    Phenylsuccinic Anhydride isn’t just handled on paper—every operator on our floor trains for irritation and combustion risks. Years in the business have shown that loose storage or open handling won’t just damage a batch, but can trigger local irritant effects. Eye protection, fume ventilation, and powder containment have become non-negotiable in the factory. Strict labeling and real-time inventory control make sure nobody mistakenly unloads the wrong drum or exposes themselves to a surprise dust plume. Adherence to these protocols comes from experience, after small mistakes led to unnecessary cleanup and occasional first-aid incidents on older lines. Factories who shortcut these steps end up with bigger headaches—there’s no substitute for habits built over years in the field.

    Supply Continuity and Market Realities

    Supply chain stories rarely get told from the manufacturer’s side, but they matter just as much as technical specs. Phenylsuccinic Anhydride’s precursors go through global commodity swings; we’ve watched benzene derivatives spike or contract with shifts in international logistics and energy markets. Holding inventory during unstable quarters, or securing multiple supplier agreements, stands as the safer move, drawn out of the real disruptions that have hit our sector over the last decade. Our field team keeps talking to logistical partners and monitoring customs policies, not just to keep shelves stocked but to keep batch traceability intact. Neither resellers nor brokers can control a dock strike or a sudden regulatory review, but we ride out those storms with contingency planning built after hard lessons.

    Supporting Innovation with Reliable Foundations

    Our bench chemists and plant operators have partnered with clients through a wave of new resin, coating, and formulation demands. With constant innovation around, one thing never changes: needing core ingredients that don’t throw surprises halfway through product development. Phenylsuccinic Anhydride gets that nod in the industry, since a predictable baseline lets formulation chemists try out new polymer backbones or additive systems without the risk of hidden reactivity pitfalls. We’ve watched research teams pivot from standard polyesters to niche, functionalized surfaces for electronics and solar coatings, and stability of input chemicals shortens their development cycles. Offering a steady, known-quantity anhydride frees those teams from extra screening or troubleshooting anonymous off-spec sources.

    Common Customer Questions—And What Experience Teaches

    On the technical hotline, we receive questions every week about physical properties, blending practices, and unusual process hiccups. Most of them center around one of three issues: shelf life, compatibility with other functionalized resins, and whether batch-to-batch purity will hold up to scale. After years in the sector, we’ve set down a handful of rules that bear out: store cool and keep dry, if flow stabilizers or antiblocking agents suit your downstream process, check with fresh bench trials, not just literature or theory, since actual melting and blending behaviors sometimes surprise. For custom projects or new reactor types, a kilogram or two of sample material often uncovers quirks in mixing or reaction times. Many users succeed by looping back findings so both supplier and client can tune future lots.

    Looking Beyond Lab-Scale Data

    Technical data sheets often get handed out as the main guarantee, but the practical world pays more attention to how crystals compact over time, how color shifts from white to cream under warehouse lights, and at what point a batch loses its convenient flow. Our team records these variables in daily operations and feeds trends right back into process tweaks or packing adjustments. Even a seemingly perfect specification slips once a six-month-old lot gets moved during humid weather or shipped across climate zones. Product isn’t always used all at once, so partial drums need resealing, and best results come from dispensing just before use. We keep the lines to our partners open for field feedback—real user data closes the gap between technical claims and operational success.

    Regulatory Environments and Traceability

    Markets in Europe, North America, and Asia now demand more than simple compliance with local chemical laws; traceability, safety documentation, and labeling standards have ratcheted up over the past decade. Each export shipment drags along a train of paperwork, and the only way to keep up proves to be tight batch controls and documentation, from raw material intake to final lot release. We maintain archives of every analytical report and shipping manifest. Regulators seek full transparency and clear labeling more than ever before. This isn’t just a hoop to jump through—it’s protection for both user and manufacturer when audits or recalls land on the industry. Getting the details right here prevents lot mix-ups, regulatory headaches, and unnecessary delays on high-value orders.

    Perspectives After Decades in Production

    A few lessons rise after years of stints at the reactor, with slow process improvement and occasional troubleshooting when customer lines stop and everyone hunts for a culprit. Stable reactivity profiles, clear melt points, and trustworthy logistics might sound straightforward, but only a manufacturer who’s lived through off-batch complaints or sudden market shortages understands the real value. We have invested in employee training, routine equipment calibration, and regular risk assessments because experience has shown that costs are lower when problems get solved before they travel downstream.

    Continuous Process Improvement

    The chemical sector doesn’t stay still, and neither does our process for making Phenylsuccinic Anhydride. Every operator suggestion, every customer inquiry, and every oddity found during shift rounds turns into a review and, if required, a tweak or upgrade. Equipment maintenance schedules shorten, quality teams introduce cross-checks between batches, and IT systems flag raw material changes in real time. External audits from major customers push these efforts further, because market leaders want to see proof of traceability, sustainable practices, and active hazard controls. Over the years, such adjustments have increased process uptime, reduced rework, and kept customer complaints to a minimum.

    Resilience in the Face of Uncertainty

    Like most specialty chemicals, Phenylsuccinic Anhydride faces rapid swings in demand and occasional disruptions in sourcing basics. We’ve put real effort into understanding where bottlenecks start—whether logistics, production capacity, or technical know-how—and addressed each through redundancy, training, and investment. Real production floor issues shape every improvement. Operators stand ready for curveballs the market throws, such as sudden customer requests for higher purity or a new grade for sensitive electronics. The ability to pivot quickly results from continuous handoffs between each department and an open channel with both suppliers and customers.

    A Closing View Grounded in Daily Work

    Phenylsuccinic Anhydride will never be just a line item on a spreadsheet for those who handle, process, and ship it around the world. From the sweat and scrutiny in the control room, to the actual packing lines, to the QC sampling benches, everything ties back to making each kilogram meet a growing benchmark of quality and utility. Consistent manufacturing, honest product feedback, and straightforward communication mean fewer pitfalls for customers, better partnerships, and shared progress in industries under constant pressure to deliver more with less. The real stories come not from brochures, but from the people who have seen the product banished from a plant for a bad batch, and worked to earn its place again, one lot at a time.