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Pentachlorobenzonitrile

    • Product Name Pentachlorobenzonitrile
    • Alias Quintozene
    • Einecs 221-836-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    401766

    Cas Number 2097-64-1
    Molecular Formula C7Cl5N
    Molecular Weight 277.35 g/mol
    Appearance White to off-white crystalline solid
    Melting Point 163-165 °C
    Density 1.86 g/cm³ (predicted)
    Solubility In Water Insoluble
    Purity Typically ≥98%
    Storage Conditions Store at room temperature, away from light and moisture
    Synonyms PCBN, 1,2,3,4,5-Pentachlorobenzonitrile
    Chemical Structure A benzene ring with five chlorine atoms and a cyano group
    Ec Number 218-272-0

    As an accredited Pentachlorobenzonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Pentachlorobenzonitrile, 99%, is packaged in a 250g amber glass bottle with a tightly sealed screw cap, clearly labeled.
    Shipping Pentachlorobenzonitrile is shipped in tightly sealed, corrosion-resistant containers to prevent moisture or air exposure. It should be labeled as hazardous, complying with local and international transport regulations. Packages must be protected from physical damage and stored separately from incompatible substances during transit, typically in a cool, dry, and well-ventilated environment.
    Storage **Pentachlorobenzonitrile** should be stored in a tightly closed container within a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers. Protect from moisture, direct sunlight, and sources of ignition. Store in a chemical storage cabinet designed for toxic or hazardous chemicals, properly labeled, and ensure access is restricted to trained personnel wearing appropriate personal protective equipment.
    Application of Pentachlorobenzonitrile

    Applications of Pentachlorobenzonitrile in Industrial Manufacturing

    Pentachlorobenzonitrile serves as a specialty intermediate in several major chemical manufacturing sectors. Produced at industrial scale in our facility, this compound plays a pivotal role in the synthesis of complex molecules, particularly within regulated downstream segments. Below we detail specific applications, required industry standards, practical formulation ratios, process stages, and finished goods categories based on actual production practices.

    1. Agrochemical Synthesis: Herbicide Intermediate

    In the agrochemical sector, pentachlorobenzonitrile acts as a key intermediate for the synthesis of commercial herbicides, notably for pyridazinone and urea-derived pesticides. Manufacturers depend on this raw material due to its controlled reactivity and high conversion yield during chlorination and subsequent condensation steps, which are integral for multi-step plant protection product manufacturing. Formulators calibrate the feed ratio to achieve target purity specs in each batch, taking into account seasonal demand and raw material purity.

    Industry compliance standards

    • EU Regulation (EC) No 1107/2009 (Plant Protection Product Authorization)
    • US EPA 40 CFR Parts 150-189 (Pesticide Registration)
    • ISO 9001:2015 (Quality Management for Agrochemical Production)
    • China GB 20684-2006 (Pesticide Manufacturing Safety)

    Typical usage ratio

    • Reaction feedstock formulation: 0.85–1.1 molar equivalents relative to chlorinated amines, adjusted to solvent loading and process throughput

    Downstream process integration

    • Charge at the initial condensation step for ring-formation synthesis of herbicidal actives, preceding catalyst addition and workup stages

    Final product types

    • Technical-grade herbicide intermediates (e.g., prometryn, metribuzin precursors)
    • Formulated selective herbicide active substances

    2. Specialty Dye and Pigment Precursors

    Pentachlorobenzonitrile is utilized by colorant manufacturing plants in the preparation of specialty pigments, especially phthalocyanine derivatives and related copper complexes, where high-chlorine aromatic nuclei are critical. The material’s purity and substitution pattern support consistent chromophore quality and batch-to-batch color uniformity, underpinning downstream synthesis reliability for high-performance dye applications in plastics and coatings.

    Industry compliance standards

    • EN 71-3 (Safety of Toy Pigments)
    • REACH (EC 1907/2006) Registration for Monomers and Colorants
    • ISO 787/Part 24 (General Methods for Pigments and Extenders—Color Measurement of Pigments)
    • ROHS 2011/65/EU (Restriction of Hazardous Substances in Electronics)

    Typical usage ratio

    • Chlorinated aromatic feed: 2.0–4.5% by weight in pigment synthesis kettle, depending on target shade intensity and copper salt loading

    Downstream process integration

    • Fed during aromatic cyclization and metal complexation phase as the core substrate for pigment molecule assembly

    Final product types

    • Phthalocyanine blue and green pigments
    • Specialty organic pigment dispersions for plastics and inks

    3. Pharmaceutical Intermediate Manufacturing

    In the pharmaceutical ingredients sector, pentachlorobenzonitrile functions as an advanced intermediate in the multi-step synthesis routes for halogenated aromatic drug molecules and intermediates intending for further derivatization. It enables introduction of high-chlorine motifs essential for structure-activity relationships in certain anti-infective and anti-inflammatory APIs. The supply complies with stringent traceability and impurity control expectations required by GMP-compliant producers.

    Industry compliance standards

    • ICH Q7 (Good Manufacturing Practice for APIs)
    • USP General Chapter <467> (Residual Solvents)
    • EU GMP Guide (Part II: Basic Requirements for Active Substances)
    • China Pharmacopoeia (ChP) applicable monographs

    Typical usage ratio

    • Batch input: 1.2–1.4 molar equivalents vs. coupling reagents, adjusted for yield optimization and carryover reduction

    Downstream process integration

    • Charged at the aromatic functionalization stage, preceding reduction or hydrolysis operations, prior to API purification

    Final product types

    • Halogenated pharmaceutical intermediates and fine chemical building blocks
    • Active pharmaceutical ingredient (API) precursors

    4. Polymer Additive Synthesis: Flame Retardant Raw Material

    Pentachlorobenzonitrile plays a supporting role in the specialty polymer additive sector, where it is processed into halogenated monomers or intermediates for non-phosphorus flame retardant blends destined for polyolefins, EPS, and PU foam systems. Its high chlorine content and compatibility with downstream alkylation and imide formation chemistry ensure formulation stability and performance criteria in finished plastics that must pass strict fire resistance verification.

    Industry compliance standards

    • UL 94 (Flammability of Plastic Materials for Parts in Devices and Appliances)
    • EN ISO 11925-2 (Reaction to Fire- Building Products)
    • RoHS EU 2011/65/EU (Restriction of Halogens in Consumer Electronics)
    • SDS/CLP (EC 1272/2008) Classification & Labelling for Chemical Entities

    Typical usage ratio

    • Raw material dosage: 3–7% by weight as flame retardant precursor in additive masterbatch compounding, subject to polymer matrix and required V-rating

    Downstream process integration

    • Converted to halogenated additives via nucleophilic substitution or catalytic fusion, then pelletized or emulsion-blended with carrier resins

    Final product types

    • Polyolefin masterbatches for flame retardant plastics
    • Rigid and flexible polyurethane foam flame retardant packages

    5. Fine Chemicals: Chlorinated Benzonitrile Derivative Production

    Manufacturers in the fine chemical segment utilize pentachlorobenzonitrile as an essential chlorinated aromatic precursor for downstream manufacturing of further substituted benzonitriles and carboxylic acids. These specialty molecules act as building blocks for advanced chemical syntheses, fragrances, and specialty monomers, where traceability and batch reproducibility are closely monitored throughout process control systems.

    Industry compliance standards

    • ISO 14001:2015 (Environmental Management for Chemical Synthesis)
    • REACH (EC 1907/2006) for Substance Registration and Notification
    • GHS (Globally Harmonized System of Classification and Labelling of Chemicals)
    • Company-specific quality specifications for process intermediates

    Typical usage ratio

    • Chlorinated nitrile charge: 1.0–1.3 equivalents as controlled feedstock in targeted substitution or hydrolysis steps; modifications depend on desired end-group selectivity

    Downstream process integration

    • Introduced during aromatic ring transformation or controlled hydrolysis, prior to downstream esterification or coupling reactions

    Final product types

    • Chlorobenzoic acids and specialty benzonitriles
    • Intermediate building blocks for aroma chemicals and advanced monomers
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    Certification & Compliance
    More Introduction

    Pentachlorobenzonitrile: Proven Reliability from the Plant Floor

    Crafted for Consistency

    Long days on the manufacturing line have taught us a simple lesson: every batch and every step matters. Our pentachlorobenzonitrile stands out for its consistency, batch after batch. We keep the purity high, and the moisture and ash low, because nothing else works in large-scale industrial synthesis. Most of the orders built in our reactors go directly to agrochemical and pharmaceutical synthesis shops, where trace unpredictability can slow down an entire run or send a process off spec. For each customer’s production plan, the payoff comes through seamless integration—not adjustments for erratic impurity levels or wild deviation from spec. This consistency stays anchored in robust, closed-loop process control and careful analytics that go far beyond the basics.

    Modeling the Difference: What Sets Pentachlorobenzonitrile Apart

    Not all chlorinated aromatics behave the same way, nor do they serve the same roles. Pentachlorobenzonitrile goes through five specific chlorination stages, which stop at a completed ring. The cyanide group substitution shapes its polarity and lets it serve as a versatile platform molecule. You’ll see a clear, distinctive difference between pentachlorobenzonitrile and earlier-stage chlorinated benzonitriles during nitrile group reactions—electronic effects and steric hindrance shift downstream chemistry. No surprise, considering every extra chloride on the ring pulls the electronic cloud, tuning the reactivity to fit only certain types of coupling. Anyone who has tried to make advanced intermediates for crop protection ingredients or specialty dyes knows that not every intermediate resists hydrolysis and thermal stress like this material does.

    Drawing the Line: Specifications That Matter

    We keep things practical. In our own process, uncontrolled variables cost us money and everybody else time. So we push our final quality test points beyond just purity. Each shipment clears thresholds on:

    Any specification below these levels leads to increased side reactions or hard-to-separate byproducts in the customer’s plant. For us, meeting specs isn’t a marketing decision—it’s a matter of keeping our own and our customers’ reactors free of unplanned downtime, extra filtration, off-colour residues, and volatile emissions. Petrochemical-grade solvents and precisely set agitation curves hold down dusting or clumping, which is especially valuable in continuous-feed lines.

    True Utility in Process Chemistry

    No substitute delivers the same yield and selectivity in many key transformations. You won’t see pentachlorobenzonitrile replaced in the backbone synthesis of specific herbicide or fungicide actives. For the teams running Grignard, halogen-metal exchange, or Sandmeyer reactions, stepwise addition and selectivity just don’t happen the same way with lower-chlorinated inputs. Trichlorobenzonitrile and tetrachlorobenzonitrile can participate in some schemes, but they often bring cascade impurities or force process changes further downstream—sometimes requiring more solvent or introducing waste disposal headaches. The fifth chloride pushes the intermediate across a stability threshold, keeping control during exothermic steps and reducing the chances of runaway contamination in mother liquor recycling.

    What We See Down the Road

    We track the pressures on the specialty chemicals world just as closely as we watch our reactors. With tightening international regulations on both product traceability and environmental impact, customers now demand cleaner processes with as little off-gas or aqueous waste as possible. Pentachlorobenzonitrile’s profile matches this need more closely than lower-chlorinated analogs, since its synthesis and use lead to fewer side products and less need for costly scrubbers or solvent extraction. We started leaning on closed systems long before new regulatory requirements came down, but those who haven’t made that investment face higher costs and more risk. Detailed batch documentation, real-time process monitoring, and revalidation all tighten the compliance net. Luckily, our current scale and control systems already meet most customer-supplier auditing requirements worldwide.

    Production Floor Experience: Not All Inputs Come Equal

    Nothing replaces hands-on exposure to an intermediate’s quirks and behavior. Pentachlorobenzonitrile handles differently from trichloro- or tetrachloro-benzo-nitriles: it resists caking, flows clean in silos, and delivers a low, steady dust level during feeding. Some years, upstream volatility in chlorine and cyanide pricing sends ripple effects through the basic chemical chain, but our feedstock contracts and on-site reclamation buffer most wild swings. Years with spot shortages or impurity-prone lots drive up costs for everyone who hasn’t invested in in-house chlorination and GC validation. Our own upstream integration gives us tools to keep timelines short for time-sensitive projects.

    Common Uses: The Tools on Every Chemist’s Bench

    The numbers tell part of the story, but customer demand tells the rest. Much of the pentachlorobenzonitrile currently shipped leaves our plant headed for agrochemical synthesis. It serves as an essential building block in creating complex, multi-ring systems found in modern pesticides and herbicides. Specialty pigment and dye manufacturers also run significant volumes through their plants when looking for strong, fade-resistant colors. Some pharmaceutical clients, particularly those developing new scaffolds for active ingredients, need a reliable source for high-purity material that doesn’t introduce catalysts poisons or sideline unwanted tars.

    You’ll rarely see pentachlorobenzonitrile directly on a label. Instead, it works upstream in transformation sequences, serving as a base structure that can carry modifications toward more complex arrays. In scale-up, engineers cite its repeatable melting point, reliable solubility in chlorinated and aromatic solvents, and shelf stability under industrial storage conditions as pluses. This intermediate tolerates multistep processing—oxidations, reductions, halide substitutions—more robustly than partial chlorination analogs.

    Differences That Shape Process Flow and Downstream Value

    Manufacturers in this field face a very real difference between our pentachlorobenzonitrile and intermediate-grade material sourced for cost savings. Lower purity and less exacting particle specifications complicate filtration, downstream crystallization, and solvent washing. These headaches mean extra passes, higher solvent costs, and more waste—hardly a bargain for any production manager who moves real volume. Some competitors focus only on cost-per-kilogram; our approach considers cost-per-successful-synthesis. Fewer breakdowns, less unplanned stoppage, and quicker lot release add up—and not just in our plant, but in customer accounts, too.

    Other suppliers may position tetrachlorobenzonitrile or trichlorobenzonitrile as close alternatives. Years of field experience contradict this idea more often than not. A missing chloride changes the molecular weight, polarity, and chemical reactivity enough to disrupt established routes. In our recent joint process trial with a major agricultural chemist, a switch to tetrachlorobenzonitrile cost several points in isolated yield, added extra purification labor, and reduced run rate due to changes in crystallization profile. We keep case notes from those experiments handy for process development teams, since the impact isn’t just theoretical—it’s written in overtime logs and solvent bills.

    Sustainability: Managing Output Beyond the Plant Gates

    The chemical industry increasingly faces a split-screen challenge: supply global material and cut the environmental footprint. Over the years, more customers have asked us to detail lifecycle assessments and to report on not just product purity, but also the handling, transportation, and fate of co-products. In response, we have closed multiple waste loops, reused energy from exothermic steps, and substituted hazardous process additives with safer choices. Pentachlorobenzonitrile, properly made and delivered with documented compliance, lets customers pass downstream audits with fewer surprises.

    Where others discharge spent streams, we recover chlorinated byproducts through controlled distillation and manage them for sale into adjacent value chains. Our approach also blends the latest process control software with boots-on-the-ground vigilance: spotting trends, reducing leak potential, and keeping public health and neighborhood impacts as low as possible. The downstream environmental advantage of pentachlorobenzonitrile lies in its clean reaction profile—fewer side products, less halogenated waste, and safer final product handling.

    Challenges: Real-World Problems With Real Solutions

    Scaling high-purity pentachlorobenzonitrile takes patience, automation, and a constant focus on reliability. Many smaller chemical factories stall at semi-batch production or rely on outside tollers, introducing uncertainties in scheduling and consistency. Our answer remains a fully integrated site with high-throughput QC, live analytics, and a well-trained shift team who expect real-time feedback. After a reactor trip or power blip, we don’t wait for surprises; the next batch gets extra scrutiny, not blind faith in numbers printed on old certificates.

    Global logistics won’t cooperate with hasty shortcuts. Regulatory scrutiny on toxic intermediates and restricted substances keeps climbing, and customs systems in major destination countries flag any documentation that doesn’t line up with accepted norms. Our logistics coordinators match package labeling, documentation, and container integrity well before each truck leaves the plant—avoiding unnecessary customs holds or lost time. Years spent resolving uncontrolled releases and shipment damage have shaped our present systems: lined containers, tamper-proof seals, and tracked chain of custody for every pallet.

    Trusted Handling: Safety Grows From Habit

    We never reduce safety to a checklist. Anyone who has met a pentachlorobenzonitrile dust cloud during transfer knows the hazards: not just acute toxicity, but the real risk of cross-contamination if dust escapes onto the wrong surfaces or into the wrong waste pathways. We keep our process sealed as tight as possible and run direct extraction and filtration at every transfer stage. Operators carry on-the-ground expertise—you learn to spot early signs of blocked lines, filter cake buildup, or off-odors long before plant monitoring systems put up an alarm.

    Well-maintained safety infrastructure—closed hoppers, negative pressure loading, and regular filter changes—shape daily production decisions. Health and safety officers partner with line leads, not just paper-pushing staff. Every time we switch drum suppliers, adjust raw material containment, or review training processes, hands-on feedback from experienced operators makes its way into protocols. This isn’t optional—one slip in handling steps costs shutdown time, possible injuries, and permanent damage to facility reputation.

    Never Standing Still: Our Commitment to Innovation

    The pressures and requirements in chemical manufacturing shift every year. New downstream applications demand cleaner, more predictable inputs. Feedback from process development teams across the globe drives us to rethink everything from reagent ratios to blending profiles to cost-out steps. In pentachlorobenzonitrile production, each optimization lets us cut flash-off losses, reduce energy consumption, and improve recovery yields.

    Collaboration runs deep through our technical group. A process is only as successful as its weakest link; so we test, break, and rebuild workflows until they meet production and regulatory goals. We’ve partnered with customers on multiple continents to adapt next-generation routes and pilot new recycling processes for spent material. Our future investments in continuous flow reactors and expanded automated analytics promise to keep both scale and flexibility high, even as customer requirements keep moving the target.

    Listening to Customers, Building Long-Term Value

    Each order for pentachlorobenzonitrile connects us with a network of R&D chemists, production engineers, and quality managers around the world. Their daily process challenges and goals shape everything we do—from raw material selection to packaging. For new customers, a lot of value lies in technical support. We don’t simply hand over a drum and walk away; troubleshooting side reactions or helping fine-tune input ratios often makes the difference between a successful launch and a costly rewrite. Customers measure value in repeatable, stable outcomes, not short-term savings on a quote.

    A major global herbicide project recently ran a pilot with our technical team onboard. Midway through plant trials, unforeseen shifts in local humidity levels started affecting powder flow and feeding rates. Instead of finger-pointing or memo shuffling, our process engineers visited the site, tracked down the cause, and suggested packaging changes and on-site silo management practices that brought operations back within specifications. This kind of direct engagement underlines how seriously we take long-term partnership.

    The Road Forward—Dependability in Every Delivery

    We remain deeply invested in every stage of pentachlorobenzonitrile manufacturing. Quality flows from consistent practice, strong relationships, and a willingness to adjust and rethink. Decades of plant management and daily interaction with operators and end-users give us a clear-eyed view of what matters—precise chemistry, real solutions, and reliability no matter the project scale. Shortcuts in quality or safety risk lives and reputation, so we keep our focus on thorough communication, process improvement, and quick response capability.

    Customers keep returning to us with new projects and higher stakes, knowing that every package and every advice comes from years of plant-floor scrutiny and lessons learned. Pentachlorobenzonitrile stands as more than a commodity—it is the result of thoughtful process control, dedication to safety, and a hands-on approach to problem-solving. Reliable performance, backed by proven expertise, shapes both the present and future of specialty chemical manufacturing.