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Oxamide

    • Product Name Oxamide
    • Alias Ethanediamide
    • Einecs 205-535-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    228298

    Chemical Name Oxamide
    Cas Number 471-46-5
    Molecular Formula C2H4N2O2
    Molecular Weight 88.07 g/mol
    Appearance White crystalline solid
    Melting Point 348–350 °C
    Solubility In Water Slightly soluble
    Density 1.90 g/cm³
    Odor Odorless
    Boiling Point Decomposes before boiling
    Main Uses Fertilizer, slow-release nitrogen source
    Storage Conditions Store in a cool, dry place
    Stability Stable under recommended storage conditions
    Hazards May cause respiratory and skin irritation
    Iupac Name Ethanediamide

    As an accredited Oxamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Oxamide is packaged in a sealed, high-density polyethylene bottle containing 500 grams, labeled with hazard symbols, product details, and safety information.
    Shipping Oxamide should be shipped in tightly sealed containers, protected from moisture and incompatible substances. It is non-flammable and not classified as hazardous for transport. During shipping, ensure the package is labeled properly and handled with care to avoid damage or spillage, following all local, national, and international transport regulations.
    Storage Oxamide should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from moisture, heat, and incompatible substances such as strong oxidizing agents. Direct sunlight and sources of ignition should be avoided. Proper labeling is essential, and access should be restricted to trained personnel. Always follow relevant safety guidelines and regulations for chemical storage.
    Application of Oxamide

    Applications of Oxamide in Industrial Manufacturing

    Oxamide serves critical roles in several industrial sectors due to its chemical stability, controlled decomposition, and specific reactivity. As an original manufacturer, we support diverse downstream processes requiring specialized integration, strict compliance, and performance-based formulation.

    1. Slow-Release Nitrogen Fertilizer Formulations

    Agricultural producers use oxamide as a key slow-release nitrogen source to improve nutrient management. The low-water solubility enables a gradual nitrogen supply to crops, minimizing leaching and volatilization losses compared to conventional urea. Formulations require precise granulation and blending to ensure uniform field application performance and compatibility with major NPK systems.

    Industry compliance standards

    • FAO Fertilizer Code of Conduct
    • ISO 8157:2015 Fertilizers and soil conditioners terminology
    • European Regulation (EC) No 2003/2003 relating to fertilizers
    • GB/T 15063-2020 (China compound fertilizers standard)

    Typical usage ratio

    • 5–30% by weight as partial or full nitrogen replacement in coated and uncoated slow-release formulations; adjust according to crop needs and soil N retention capability

    Downstream process integration

    • Added during granule blending or extrusion phases; often coated or encapsulated
    • Mixed with phosphates or potash as dry blends or compound fertilizers
    • Integrated into multi-nutrient controlled-release systems
    • Subject to field-specific formulation adjustments for paddy, maize, or horticultural use

    Final product types

    • Slow-release granulated nitrogen fertilizers (bulk or specialty grade)
    • Compound NPK fertilizers for cereals and cash crops
    • Custom-coated fertilizers for greenhouse or turf applications
    • Environmentally adaptive fertilizers for regulated farming systems

    2. Flame Retardant Formulations in High-Performance Polymers

    Composite and plastics manufacturers employ oxamide to develop halogen-free flame retardants, especially for polyamides and thermosetting resins. The compound decomposes endothermically and releases inert gases, enhancing fire resistance without introducing additional toxicity. Selection of particle size distribution and surface treatment determines the integration efficiency during compounding.

    Industry compliance standards

    • UL 94 Vertical and Horizontal Burning Tests
    • RoHS Directive 2011/65/EU (Restriction of Hazardous Substances)
    • EN 13501-1 (Fire classification for construction products)
    • REACH registration requirements (EU)

    Typical usage ratio

    • 3–12% by mass, depending on target flammability rating and polymer matrix (higher in glass-fiber reinforced nylon); pilot batches establish dosage in line with test performance

    Downstream process integration

    • Dispersion in polymer melt during twin-screw extrusion
    • Pre-mixed with resin fillers or pigments in masterbatch form
    • Added before molding or pelletizing operations
    • Direct dosing into injection or compression molding lines

    Final product types

    • Flame-retardant polyamide (PA6, PA66) components
    • Electrical enclosures and connector housings
    • Automotive trim and structural modules
    • Building construction panels and fixtures

    3. Catalyst in Organic Synthesis for Pharmaceutical Manufacturing

    Pharmaceutical synthesis operations leverage oxamide as a nitrogen-donating catalyst or reagent, notably in transition metal-catalyzed cross-coupling reactions and amidation steps. The precise purity and low trace metal content required for GMP manufacturing are controlled during production. Process engineers calibrate oxamide dosage to balance reaction kinetics and product purity.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP <823> for chemical manufacturing
    • FDA 21 CFR Part 211 (Current GMP for pharmaceuticals)
    • EP (European Pharmacopoeia) standards for starting materials

    Typical usage ratio

    • Stoichiometric to catalytic amounts (typically 0.2–2 mol equivalents), optimized per reaction type and pathway; subject to QC-approved batch documentation

    Downstream process integration

    • Dosed to reaction vessels at specified stage (base, ligand, or direct reactant)
    • Integrated in multi-step synthesis where amide bond formation or selective hydrolysis is critical
    • Removed through downstream purification (filtration or crystallization)
    • QC batch testing for trace impurities and contaminant control

    Final product types

    • Pharmaceutical intermediates with enhanced yield or purity
    • API precursor compounds via amidation or cross-coupling
    • Research toolkits for drug development laboratories
    • Fine chemical building blocks for veterinary pharmaceuticals

    4. Foaming Agent in Rubber and Plastic Processing

    Oxamide acts as a chemical blowing agent in foamed elastomers and thermoplastics. Upon thermal decomposition, it releases gases such as CO₂ and ammonia, enabling controlled cell morphology in shoes, insulation panels, and automotive parts. Manufacturers select grade and particle size to fit batch or continuous foaming equipment, optimizing pore uniformity and mechanical performance.

    Industry compliance standards

    • ISO 24153:2022 (Industrial foams, general specifications)
    • ASTM D3575 for flexible cellular materials
    • GB/T 4839-2017 (Plastic foams, China)
    • REACH (EC1907/2006) registration for polymer additives

    Typical usage ratio

    • 0.5–3% by weight, depending on foam expansion target and end-use thickness; refined by trial runs on production-scale lines

    Downstream process integration

    • Blended with polymer resin before extrusion or molding
    • Incorporated into masterbatches for batch foaming
    • Dosed during injection molding or calendaring stages
    • Post-foaming physical tests ensure uniform gas release and structure

    Final product types

    • Lightweight EVA or PE shoe soles
    • Thermal insulation boards for construction
    • Noise-reducing foam inserts for vehicles
    • Foamed mats and packaging spacers

    5. Solid Fuel Tablet and Propellant Production

    Solid fuel and outdoor product manufacturers rely on oxamide to control burn rate and suppress flame temperature in smokeless fuel tablets and specific propellant blends. Its decomposition delays ignition and moderates combustion kinetics, supporting uniform heat profiles. Dosage must be carefully matched to fuel matrix for target burn time and emission properties according to regulatory test standards.

    Industry compliance standards

    • UN Recommendations on the Transport of Dangerous Goods
    • EN 1860-3 (Solid fuels, firelighters, and ignition products)
    • US DOT Hazardous Materials Regulations 49 CFR
    • ISO 9151:2017 (Solid propellants, test methods)

    Typical usage ratio

    • 2–7% by mass in solid fuel blends; rate determined by desired burn duration and specific heat output

    Downstream process integration

    • Dry blended with fuel base materials (hexamine, paraffin, or sugar)
    • Compressed into briquettes or tablets via hydraulic or rotary presses
    • Integrated into double-base propellant grains for controlled ignition
    • Quality tested for ignition delay, calorific value, and emissions profile

    Final product types

    • Solid fuel cooking tablets for camping or emergency use
    • Model rocket propellant charges
    • Specialty slow-burn ignition pads
    • Military field heating rations
    Free Quote

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    Certification & Compliance
    More Introduction

    Oxamide: A Practical Choice for Reliable Nitrogen Release

    What Makes Oxamide Stand Out?

    Having worked at the core of chemical production, I've come to see how Oxamide brings a quiet reliability to a range of industries. In our facility, we’ve spent years refining the synthesis of Oxamide to reach the kind of purity and consistency that lab technicians, researchers, and farmers trust. Its formula, C2H4N2O2, looks simple on paper, but the difference shows in the details: controlled crystallization, steady particle size, and full traceability from batch to batch. We know each client cares about predictable results, especially with input costs and environmental impact under tighter scrutiny.

    Understanding Specifications That Matter

    The Oxamide that leaves our factory carries a minimum purity of 99 percent, based on industry-standard testing. By maintaining low moisture content and keeping impurities at bay, users avoid the problem of product clumping during storage or application. The granule size falls in the range preferred for most precision applications, because we heard early on from partners that inconsistent sizing led to dosing headaches and uneven flow. The bright white crystalline powder often draws comments for its clean appearance, which reflects the quality we aim for—not just visual appeal.

    Though the chemical structure does not change, we pay attention to batch-to-batch performance. We document tests for solubility, checking that each lot dissolves at expected rates under standard conditions. Our quality managers flag any deviation well before a shipment leaves the site. This diligence pays off on the client end, since nobody wants surprises in a production line or on a test bench.

    Key Applications Where Oxamide Shines

    Oxamide finds its biggest fans among specialty fertilizer formulators. In our experience, this material doesn’t release nitrogen quickly like urea; it takes much longer to break down in soil. This slow hydrolysis means that crops receive a gradual, sustained supply of nitrogen, especially on fields that suffer runoff from standard fertilizers. Many of the testimonials we receive come from agronomists who compare Oxamide blends to urea and see reductions in nitrogen leaching and more even crop response over time.

    We also see demand from labs and research outfits that rely on Oxamide as a calibration standard. Its consistent nitrogen content lets technicians avoid recalibrating for purity drift. Those who need a slow-release nitrogen source in controlled experiments say they choose Oxamide for its predictable effects. There are also creators of specialty plastic foams who have come to depend on it. Thanks to Oxamide’s ability to serve as a foam suppressant and as a component in some thermosetting resins, there’s always a niche market beyond just fertilizer.

    The Real Differences – Oxamide Versus Other Nitrogen Products

    After years in this industry, I’ve noticed plenty of confusion between Oxamide and more common options like urea or ammonium nitrate. The main difference comes down to how nitrogen availability unfolds. Urea delivers a fast punch—sometimes too fast—especially after irrigation or rain, leading to waste and higher environmental losses. Ammonium nitrate gives a strong immediate effect, but regulations continue to tighten around its use due to security concerns.

    What separates Oxamide is its notably slow breakdown in the environment. Hydrolysis tends to lag behind all the usual suspects. This isn’t because we slow anything down; it’s just a property of the molecule. For fields where uniform, extended nitrogen release is worth more than a rapid flush of growth, Oxamide finds its place. Some customers tell us they blend Oxamide with urea to get both short-term and long-term feeding. This approach would be pointless if the two products broke down at the same rate.

    Comparing with coated or encapsulated nitrogen sources, you dodge the complication of layer defects or residue left behind in soil. Coatings can fail; we’ve seen enough returns over the years to know this. Oxamide avoids that layer of complexity. Its durability against leaching makes it suitable for use in regions with sandy soil or heavy rainfall—places where urea washes away before the roots can draw it in.

    Formulation and Handling

    Through multiple client audits, we identified some common concerns: product caking during storage, handling safety, and ease of mixing into blends. To address these, our plant has invested in humidity control and automated packing systems; you rarely see a product leaving here with excess moisture. Packaging choices have evolved in response to user feedback. From paper sacks to polyethylene-lined bags, we aim for options that strike a balance between sustainability and protection. Warehouse managers appreciate not having to break apart clumped material or lose time to equipment blockages.

    In terms of flow properties, our Oxamide’s median particle size sits in the sweet spot for both hand mixing and large-scale granulation. On any given run, mill operators check screens and adjust for fines, since those can create dust issues for downstream equipment. We always encourage customers to store Oxamide in a cool, dry area—no need for refrigeration, just shelter from any direct source of liquid moisture. Chemical stability means it remains unchanged for a long period, so distributors experience fewer problems with shelf life compared to ammonium or urea products that sustain some decomposition if humidity creeps in.

    Those working in formulation labs have pointed out how easily Oxamide blends with inert supports and trace micronutrients. It resists forming unexpected byproducts and doesn’t introduce strong odors. Blending teams keep documentation on each process, always aiming to prevent cross-contamination and trace any issues back to their source. We partner with customers on formulation trials, sharing sampling data and process notes to help fine-tune blends for specific crops or specialty market demands.

    Environmental Perspective

    Oxamide has built a name as a cleaner alternative. Its slow hydrolysis means less nitrate leaching and denitrification, two key loss pathways driving regulatory pressure on growers. In groundwater protection trials, fields using Oxamide showed measurable reductions in nitrate accumulation compared to plots treated with urea—evidence confirmed by independent labs. This is one reason many in environmentally sensitive zones prefer it, especially those working near waterways or relying on groundwater as a principal source of irrigation.

    Our team runs lifecycle assessments each year to measure total greenhouse gas emissions from production to delivery. Raw material choices, energy mix, and plant upgrades all feed into these calculations. Customers ask about the carbon footprint, and Oxamide performs well thanks to lower application rates and less need for reapplication. A lot of nitrogen applied as urea gets lost as airborne emissions, which contributes to overall agricultural emissions targets. With Oxamide, you see not only cost savings over time, but a more sustainable approach to nitrogen management.

    Farmers experimenting with regenerative agriculture have approached us in recent years, testing Oxamide for minimal-impact fertilization. It blends neatly with organic amendments and doesn’t disrupt soil biology the way some synthetic options do. Our trials with local growers confirm you can maintain yield without sacrificing stewardship of the land. This isn’t just theory—we’ve walked those fields, measured the nutrient content, and seen the difference at harvest.

    Handling Safety and Regulatory Confidence

    Safety officers often review our process data during plant tours. Oxamide won’t classify as an explosive risk or hazardous oxidizer, which puts users’ minds at ease. It has a moderate toxicity level, much lower than ammonium-based alternatives, so accidental exposure doesn’t trigger the same level of concern as regulated substances. Our plant follows strict protocols for dust management, since inhaling any fine powder gets uncomfortable and can cause complications for asthma sufferers. Workers wear standard protective gear—no need for extreme containment.

    We regularly host audits by external certifiers and maintain transparent records, so agricultural compliance inspectors or quality managers can check our chain of custody. Oxamide’s registration status means it clears barriers for use in multiple countries and export markets. We respond quickly to requests for documentation on purity, batch origin, and compliance with food-safety standards. In all the years we’ve shipped this material, we have yet to encounter a recall—something we attribute to careful monitoring, well-maintained equipment, and daily operator training.

    Challenges and Solutions in Oxamide Production

    Producing Oxamide at scale comes with its own learning curve. The process itself involves controlled reaction of cyanamide with water under set temperature and pH. Achieving maximum yield without wasting raw material takes real-world tinkering with reactor design and agitation settings. Earlier plants struggled with side reactions that formed unwanted byproducts, but our engineering team spent several seasons fine-tuning reactor internals and automating feed rates to hit tighter production tolerances.

    Waste management marks another area where we have made significant progress. Any unreacted material or process filtrate undergoes on-site recycling, which both cuts disposal costs and reduces environmental exposure. Operators periodically review these steps to catch any anomalies early on. Continuous improvement shapes our daily workflow—new meters, smarter alarms, and feedback loops linking lab reports to process control systems. Quality never relies entirely on machinery; operator skill still makes the difference between a routine batch and off-spec material.

    Occasionally, supply chain interruptions for key starting materials create scheduling headaches. We maintain buffer inventory and long-term supplier partnerships, keeping open lines of communication in case raw material pricing or logistics shift. These relationships give forewarning and flexibility that traders in the middle often lack. Our material planners regularly review projections with client deadlines to keep orders moving, even when global shipping strains put pressure on timelines.

    Field Feedback and Ongoing Development

    The most meaningful product improvements have come from customers. Season after season, we get field notes describing how Oxamide performed—across climates, cropping systems, and application technologies. One midwestern grower shared records from side-by-side trials comparing our Oxamide blend with uncoated urea. The rows treated with our product kept a steady green color and needed less midseason rescue fertilization, even after heavy rains. That direct feedback moves the needle more than any advertising copy.

    We adapt to new application trends, too. Precision agriculture tools now let users map input delivery across every acre. In response, our R&D team tests customized particle sizing to run through advanced variable-rate spreaders. Resistance to moisture and caking continues to improve. As new market requirements appear—higher granule crush strength, tighter dust limits, low-temperature solubility testing—our plant shifts to trial production runs until we hit the specification that matches customer goals.

    Collaboration with downstream blenders has guided packaging upgrades: thicker liners for humid coastlines, stackable bags for warehouse efficiency, and tamper-evident seals for traceable distribution. The days when customers accepted generic bags filled with unknown filler are gone. People ask about every detail. We welcome those questions, as they push our team to keep raising the bar.

    Supporting Users Through Experience and Know-How

    Clients reach out to us with practical concerns. How will Oxamide perform in cold soils? Does it interact with plant hormones or other micronutrients? We run bench trials, then document outcomes in plain language. Our technical team brings firsthand knowledge to each query, sharing results that other producers often shelter behind proprietary restrictions. Every claim we make about performance traces back to data collected in our own facility or from carefully documented customer trials.

    For those switching from conventional fertilizers, we recommend piloting Oxamide on several fields before full conversion. Application rates follow crop-specific guidelines, adjusted based on local climate and soil conditions. Farm advisors who specialize in environmental monitoring now integrate Oxamide into nitrate leaching studies, soil health assessments, and carbon credit pilots. Those collaborations pull our product into the broader sustainability conversation.

    Training makes a difference—not just for our own operators, but for end users as well. We regularly provide on-site support, product demonstrations, and troubleshooting sessions. One greenhouse operator who switched to Oxamide described how his irrigation system sustained less clogging, with more consistent crop uptake. That kind of confidence turns a first-time buyer into a long-term partner.

    Research, Standards, and the Future of Nitrogen Management

    Academics and private labs continue to explore new uses for Oxamide, from advanced controlled-release coatings to water treatment additives. We participate in these research networks, sharing anonymized production samples for independent study. Results that come back—especially regarding nitrate runoff and crop uptake—inform policy conversations at both national and international levels.

    Production standards are always rising. Food processors ask for tighter purity specs, seeking to avoid contamination and ensure regulatory approval for exports. Agricultural buyers watch for performance over “one-size-fits-all” approaches. Through all these shifts, Oxamide keeps a reputation for dependability. The only way to maintain that is by always listening to users, investing in process improvements, and sharing knowledge that expands practical outcomes.

    Looking forward, we expect demand for stable, slow-release nitrogen sources to climb. Water quality laws, input cost pressures, and soil health initiatives all converge here. Oxamide isn’t the answer to every problem, but it closes several key gaps in the nitrogen management puzzle. Our job as a manufacturer is to stay ahead by responding directly to what users experience in the field—not just laboratory assumptions.

    Conclusion

    Oxamide hasn’t received the same spotlight as old standards like urea or ammonium nitrate, but those who rely on consistent, slow-release nitrogen appreciate its value. Durable performance, predictable results in both research and field settings, and lower environmental risks define its place in today’s lineup of nitrogen products. From our end as a manufacturer, we see Oxamide’s contribution not in flashy claims, but in repeat orders and steady feedback from users who trust their results year after year. That’s the reputation we work for, batch after batch.