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Oxamic Acid

    • Product Name Oxamic Acid
    • Alias Aminocarboxylic acid
    • Einecs 211-672-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    337839

    Chemicalname Oxamic Acid
    Casnumber 471-47-6
    Molecularformula C2H3NO3
    Molecularweight 89.05 g/mol
    Appearance White crystalline solid
    Meltingpoint 187-190°C
    Solubility Soluble in water
    Boilingpoint Decomposes before boiling
    Density 1.672 g/cm³
    Ph 2.1 (10 g/L, H2O, 20 °C)
    Synonyms Aminoformic acid, Amidoformic acid
    Smiles C(=O)(N)C(=O)O

    As an accredited Oxamic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Oxamic Acid is packaged in a 500g white HDPE bottle, sealed with a screw-cap lid, and labeled with hazard and product information.
    Shipping Oxamic acid should be shipped in tightly sealed containers, protected from moisture and incompatible substances. It must be clearly labeled and handled according to local, national, and international regulations for chemical transport. During shipping, ensure the package prevents spillage or leakage and comply with all hazard communication standards, including safety documentation.
    Storage Oxamic acid should be stored in a cool, dry, well-ventilated area, away from sources of moisture and incompatible substances such as strong oxidizers. Keep the container tightly closed to prevent contamination and absorption of moisture. Store at room temperature, away from direct sunlight and heat. Use corrosion-resistant containers, and ensure proper labeling for easy identification and safe handling.
    Application of Oxamic Acid

    Applications of Oxamic Acid in Industrial Manufacturing

    Oxamic acid, as a specialty organic compound, serves critical roles as an intermediate, modifier, or process aid in select industrial manufacturing sectors. Our customers deploy this material in their core production lines for its distinct molecular reactivity, enabling precise process outcomes. Below, we highlight authentic downstream application scenarios, detailing industrial standards, formulation proportions, operational integration points, and resulting finished products based on real-world customer usage.

    1. Textile Dyeing and Printing Auxiliaries

    Textile manufacturers utilize oxamic acid during dyeing and printing processes to fine-tune the fixation and brightness of metal-complex dyes, especially in the wool and polyamide segments. The compound’s chelating ability controls trace metal ions present from raw water or in-fiber, ensuring dye uptake constancy and color reproducibility across bulk lots. Its use requires close adherence to regional textile chemical guidelines, particularly for exports to regulated markets. Our customers have reported reduced occurrence of batch shade deviation and improved post-dye fastness properties when including this step in vats and continuous lines.

    Industry compliance standards

    • OEKO-TEX® Standard 100
    • ZDHC MRSL Chemical Restrictions
    • GB/T 18401 (China National Textile Safety Standard)
    • REACH Regulation (EC) No 1907/2006 for chemicals in textiles

    Typical usage ratio

    • Between 0.2% and 1.2% (w/w) on fiber weight, depending on dye type and metal ion levels in process water; technicians adjust in the laboratory for each dyehouse recipe.

    Downstream process integration

    • Dosage in dye liquor upstream of dye addition; sometimes split between pre-mordant and dye bath liquor, monitored via titration or colorimetric indicators for optimal timing.

    Final product types

    • Acid-dyed wool yarns and fabrics
    • Nylon textile goods for apparel or interiors
    • Polyamide-based engineered fabrics
    • Garment-grade and technical textile products

    2. Fine Chemical Synthesis – Pyrimidine and Barbiturate Manufacturing

    Producers of pharmaceutical and agrochemical actives employ oxamic acid as a carbon-nitrogen source or reagent in multi-step fine chemical synthesis. It participates in ring closure or amidation reactions crucial for pyrimidine and barbiturate core formation. Its predictable reactivity profile supports batch quality reproducibility and trace impurity control, demanded by regulatory agencies overseeing active pharmaceutical ingredient precursors or high-purity pesticides. Companies register their processes and finished goods according to internationally harmonized pharmacopeia monographs and GMP quality management frameworks.

    Industry compliance standards

    • ICH Q7 GMP Guidance for APIs
    • USP-NF and Ph. Eur. (compendial grade requirements for starting materials)
    • 21 CFR Part 211 (US FDA Good Manufacturing Practice)
    • ISO 9001:2015 certified quality systems

    Typical usage ratio

    • Ranges from equimolar to 1.5× stoichiometric equivalents relative to amine or urea reactants; process development teams determine ratio by reaction yield and side-product minimization targets; typical batch scale: 5–20% by mass of total reactant input.

    Downstream process integration

    • Charged to reactors either as a dry powder during the charging step or as a pre-dissolved solution in water or polar solvents; used in conjunction with dehydrating agents or condensation catalysts under controlled temperature profiles.

    Final product types

    • Pyrimidine derivatives (pharmaceutical intermediates)
    • Barbituric acid and related heterocycles
    • Sulfonamide or triazine building blocks
    • Crop protection actives for formulated plant protection products

    3. Electroplating Process Chelant and Bath Stabilizer

    Component finishing facilities handling electroplated parts incorporate oxamic acid as a specialized chelating agent and stabilizer in nickel and copper bath systems. Its moderate chelation strength regulates free ion activity, supporting uniform deposition and controlling microcrystalline structure of plated layers. Adoption complies with industry demands for surface integrity on electronic connectors, metal closures, and automotive components. Operators customize addition rates according to continuous inline conductivity and bath composition analytics.

    Industry compliance standards

    • ASTM B571 (Electroplated Coatings Quality Testing)
    • IEC 62321 (RoHS hazardous substance limitation in coatings)
    • ISO 4527 (Nickel coating process quality)
    • Automotive OEM plating chemical requirements (e.g., VW, BMW, GM in North America & Europe)

    Typical usage ratio

    • 20–120 g/L in electroplating baths; setpoint depends on metal turnover rate, bath volume, and presence of trace contaminants, with onsite titration supporting in-process adjustments.

    Downstream process integration

    • Pulled directly into automated bath dosing stations, pre-dissolved in controlled quantity per litre of bath; continuous or manual top-up, with regular monitoring via UV-Vis or ion chromatography for bath maintenance.

    Final product types

    • Nickel/bronze-plated electrical connectors
    • Zincate copper alloy machine parts
    • Consumer electronics surface contacts
    • Functional automotive or aerospace plated fasteners

    4. Cement Grinding Aid Formulations

    The construction material sector includes oxamic acid in specialty cement grinding aid blends, engineered to modify cement particle agglomeration and control mill operation efficiency. By altering electrostatic forces during milling, it limits excessive clumping and supports consistent product fineness, directly influencing downstream cement hydration profiles and final mortar or concrete performance. Blenders must demonstrate compliance with strict construction chemical standards and building code toxicology restrictions for additives.

    Industry compliance standards

    • EN 197-1 (European Cement Standard)
    • ASTM C465 (Specification for Processing Additions in Cement)
    • REACH registered for building uses
    • GB 8076 (China Standard for Concrete Admixtures)

    Typical usage ratio

    • Generally 0.01%–0.08% by cement weight, adjusted based on clinker properties, mill throughput, and moisture profile; determined via QC trials for each formulation batch.

    Downstream process integration

    • Introduced with other grinding aids to raw clinker feeding zone of high-capacity ball mills or vertical roller mills; operator control via automated liquid dosing or direct powder injection.

    Final product types

    • Bulk Portland cements (42.5R, 52.5R, etc.)
    • Ready-mix binder blends
    • Pre-cast concrete slab and construction panel feeds
    • Dry-mix mortar base powders for civil engineering

    5. Analytical Reagent in Rare Earth Metallurgy

    Rare earth processing refineries employ oxamic acid as a selective precipitant or masking reagent in the analytical separation and purification of lanthanides. The compound’s selectivity towards certain rare earth ions enables critical separation steps in hydrometallurgical flowsheets, particularly in the purification stages preceding oxide conversion. Regulatory-driven demand for trace impurity control in high-performance magnets and phosphors drives adoption, where laboratories must document reagent composition and procedural traceability for each batch output.

    Industry compliance standards

    • ISO 9001/14001 Management Systems for rare earth processing
    • GB/T 14832 (Chinese Standard for REE Chemical Purity)
    • ASTM E1601 (Standard Guide for Evaluation of Rare Earth Methods)
    • OECD Due Diligence Guidance for Responsible Mineral Supply Chains

    Typical usage ratio

    • Stoichiometric ratios based on targeted lanthanide content; 2–10 g/L concentrations in process solutions, with adjustment according to batch composition and target rare earths for isolation.

    Downstream process integration

    • Dosed during counter-current solvent extraction, solution precipitation or ion exchange stage; often introduced post leaching and pre calcination in oxide or carbonate conversion lines.

    Final product types

    • High-purity lanthanide oxides (Nd2O3, Pr6O11, etc.)
    • Rare earth metal ingots for neodymium-iron-boron magnets
    • Colorimetric rare earth salts for catalyst and phosphor blends
    • Battery-grade mixed rare earth compounds
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    Certification & Compliance
    More Introduction

    Oxamic Acid: From Our Plant to Practical Solutions

    Introducing Oxamic Acid and Its Place in Real-World Chemistry

    As a chemical manufacturer, every product we make needs to justify its role in the supply chain. Oxamic acid has earned its keep here, not by following trends, but by staying reliable through years of shifting demand. The chemical formula C2H3NO3 tells the story at a molecular level, though for most practical users, this comes down to a white crystalline solid that does one job particularly well: acting as a key building block or processing aid where standard organics fall short. The grade our facility produces is the result of carefully managed purification steps, each batch verified for a minimum assay of 98%. We typically ship it out in 25 kg fiber drums, double-lined, to keep moisture out and keep the product as stable when it leaves our loading bay as when it got off the filter.

    What We’ve Learned About Oxamic Acid in Practice

    Years ago, requests for oxamic acid came mainly from niche textile facilities. Technicians needed something better at fixing color or regulating dye behavior, searching for effects that common acids brought only with too much collateral corrosion or too much scale formation in evaporators. In those days, more than one supplier tried to make do with oxalic acid instead, since it was cheaper and more common. What our customers learned, often at a steep cost, was that oxamic acid outperformed when precision mattered – it binds calcium but with less solubility for side reactions, slowing down the rate of unwanted complexes and lowering unwanted deposit formation.

    We see this practical difference every time we analyze solids left behind in industrial reaction kettles. Direct replacement with oxalic acid increased downtime, wasted hours on cleaning, and reduced yields, even though the documents suggested near-interchangeability. It’s these stories on the plant floor that drive our engineering staff to keep tightening our particle size control and screening technology. We run our oxamic acid through detailed sieving, delivering a consistent mesh size distribution that saves our clients unexpected labor and keeps their continuous processes stable.

    Key Specifications That Matter Most on the Job

    Oxamic acid might look simple enough on a chemist’s stock list, but under the microscope, minute differences in purity, particle shape, and moisture content tell a different story. The technical documentation describes a white to almost-white crystalline powder, soothed to below 0.5% moisture, and checked for iron content below 10 parts per million. These benchmarks mean something to us beyond compliance. Over the years, even small shortfalls showed up as brownish streaks or unexpected coloring in synthetic fiber lines or as undissolved grit in high-speed reactors.

    Many labs have shared feedback with us over the years: a handful of rejected lots from competitors sent for reprocessing, issues tracking back to low-purity batches blended into larger stocks or high-chloride residues corroding reactor surfaces. We made it our routine to double-test for chloride and sulfate, despite some buyers not asking for these numbers upfront. In labs using oxamic acid as an intermediate for peptide synthesis or specialty chelation, chloride levels have to stay below 100 ppm to keep downstream reactions predictable.

    For larger-scale applications, we outfit our packaging with hermetic seals and robust liners. Oxamic acid should reach the customer as free-flowing as it leaves our drying oven. Moisture absorption during transport destabilizes not only the acid itself but every blend or paste it touches later down the line. We’ve learned from export shipments halted at ports due to caking or lump formation, so we work closely with logistics crews to minimize time spent in humid transit zones. This direct management approach allowed several pharmaceutical partners to skip costly regrinding steps and plug the material straight into high-shear batch reactors.

    Speaking with Customers About Application – What Matters in the Field

    Our plant staff handle a steady stream of calls ranging from industrial dyehouses to specialty pharma blenders, with each application demanding something different. For instance, dyestuff formulators need an oxamic acid that dissolves predictably under steam conditions and doesn’t provoke rapid precipitation as temperatures drop or as the water composition changes. Our tests at different pH levels and hardnesses allow us to deliver practical advice along with the consignments. Textile blenders once reported an off-tone in a magenta batch after switching to an alternative supplier. After tracing the batch’s trace elements, we found higher iron and manganese. These elements tip dye equilibria off-balance, leading to color drift that costs plenty over repeated production cycles.

    For research-scale users, especially those testing new peptide coupling reagents or catalyst supports, small lots of high-purity oxamic acid get packed in antimicrobial vials and shipped cool. Requests for certificate of analysis on trace aldehydes or residual heavy metals come not from compliance checklists, but from past bad experiences where single-digit ppm contaminants led to hours of troubleshooting. We know every minute lost in those labs means delayed publications or failed project deadlines, so we’ve invested in fast, on-site spectral scanning rather than sending material for third-party testing.

    In the agricultural sector, oxamic acid made its way into niche roles as a stabilizer or intermediate for certain crop-protection formulations. Users here have little margin for error—a wet product clogs nozzles, and a dusty batch chokes pumps. Our slotted filling machines measure weights precise to under one gram, and an in-line moisture probe flags any deviation from spec before the drum is sealed. Field feedback showed these steps cut downtime in half over competitor batches, and saved on unplanned maintenance.

    Real-World Benefits Over Other Products

    Comparing oxamic acid directly to older standards, such as oxalic or succinic acids, conversations quickly move from paper properties to real process results. Oxamic acid stands out for its intermediate solubility and gentle reaction profile. Oxalic acid, while cheap and highly soluble, produces too many side reactions and traps metal ions too aggressively, leading to scale, poor color registration in textiles, or contaminated end products. Users who swapped back after problems noted heavy buildup on heat exchangers and fouling that other acids did not provoke.

    Whereas conventional acids cause rapid pH drops and unmanageable reaction rates, oxamic acid tempers the process, reducing risk of runaway conditions in batch reactors. That matters in pharmaceutical synthesis, where yield is king and unreacted materials can spoil entire campaigns. In our experience, 99% pure oxamic acid can reduce process deviations and cleaning cycles, with documented process uptimes improving by up to 20% in partner plants over a six-month window.

    Buyers also look closely at storage and stability. Oxalic acid cakes and hardens once exposed to ambient moisture, clumping inside drums until it needs hammering loose—a problem warehouse staff face too often. We addressed this with finer particle control and nitrogen-purged drum liners, a detail that let our oxamic acid travel across continents without forming a solid mass. Some other manufacturers claim caking can be broken with agitation. From our hands-on work, this approach is costly and leads to losses. Our batches pass drop tests and long-haul shipping runs without the typical losses you see from cheaper, loosely packaged alternatives.

    Supporting Data and Plant Insights

    Oxamic acid’s molecular structure brings selective chelation properties, useful in metal extraction and advanced catalyst formation. Labs running comparative titrations see steadier chelation with our product, a result of years spent minimizing iron and copper residue. For clients using it as a component in corrosion inhibitors in oil and gas lines, the combination of high-purity and low-chloride content leads to noticeably reduced pitting on 304 stainless steel after prolonged exposure cycles.

    Students and professors often reach out for data on thermal stability, especially for planned large-scale-up tests. Our own plant trials found oxamic acid remains stable up to 170°C before major decomposition. For those working above this range, we help model reaction controls that avoid surges in CO2 evolution. Many years ago, a partner plant running at the upper edge of spec hit a major snag: competitive material decarboxylated under load, forming gas bubbles and sending product into reject. Our tighter control, through in-process GC analysis, prevented this botched batch from happening again.

    The right blend of physical and chemical controls at production lets us trace every batch back to the starting glycolic acid, down to lot and supplier. If a customer reports off-color or low-flow issues, we can run a sample backward through the process, check evaporator logs, and correlate with particle sizing. This direct connection between production, QA, and technical support saves clients—especially those new to oxamic acid—the pains of trial-and-error sourcing.

    Working Directly With the Supply Chain

    Manufacturing teaches the value of clear, honest feedback loops. Over the years, we worked closely with procurement teams, technical officers, and even end-process operators to understand not just why oxamic acid was ordered, but how it performed. Batch rejections often traced to misunderstandings about the role of trace impurities or the behavior of the powder itself under mechanical stress.

    Every successful repeat order started with getting these details right. In major textile mills, successful start-up of new color lines used our high-purity oxamic acid as a control, benchmarking against blends with oxalic acid that left behind residue. Process engineers learned to trust the stability and to time their additions, maintaining process pH far more effectively. Raw feedback—ranging from direct plant visits to unsolicited photos of cleaned lines—shaped our output from bulk drums down to lab packs.

    For custom production runs, the lab and plant crew run small-scale evaporation, crystallization, and drying steps in parallel to scale batches safely. We use the feedback to trim cycle times and to adjust anti-caking steps or washing procedures. This isn’t just a game of hitting target purities—it’s grown from real headaches in failed product launches, ruined crops in field trials, and QC hold-ups tied back to tiny process tweaks.

    Continuous Improvement Means Chasing Practical Results

    Oxamic acid has found new life every time a client tests limits on purity, packaging, or application. Several global pharma companies began with trial batches, measuring yield and isolating contamination patterns. Over months of exchange, they shared invaluable insights—data on reaction fouling, unexpected byproduct formation, or lost output to handling setbacks. These real-world stories helped push our standards higher. Instead of just meeting local certificates, we began running extended stability studies, both under desert and tropical conditions. These tests exposed issues early, letting us dial in process controls long before they manifested in a customer’s plant.

    Feedback cycles led us to introduce smaller, double-sealed packs and offer thorough technical documentation as standard. The paperwork describes details like spectral fingerprints and particle size distribution, so downstream QC personnel can verify our claims before ever using the material. Trust is built not just by delivering purity, but by helping buyers avoid hidden downtime or scrapped lots.

    Beyond the Factory Gate: Partnerships Built on Experience

    Major chemical companies experiment constantly with their supply chains, but the plants that stay flexible, and listen to end-users, improve over time. Over three decades, our oxamic acid production grew from modest local shipments to a key ingredient for dozens of industries, each with stubborn process quirks to solve. Many technicians now expect more than just a drum of product: they demand support on water compatibility, blending behavior, and even regulatory assurance, especially for food and pharma touchpoints.

    Our staff have stood on plant floors, knee-deep in finished goods, troubleshooting the same problems that users face daily. We learned that the right packaging, consistent mesh, and reliable purity are worth more than pennies saved upfront buying from less careful producers. Failures—crystallizer fouling, sludge in process lines, lost production days—stick in the mind much longer than line-item savings. Every change in process at our plant tracks to real-world headaches we’ve seen or solved for customers.

    Why Oxamic Acid Remains a Cornerstone for Quality-Driven Operations

    Unlike catalogues filled with unproven specialty acids, oxamic acid shows up in the same real-world uses decade after decade. Periodic changes in dye chemistry, water composition, or technical standards force formulators to reconsider their choice of intermediates, but so far, oxamic acid keeps proving itself whenever process control rises in importance. It attracts repeat buyers not with flashy marketing, but by delivering a chemical workhorse for exacting processes.

    Process chemists tell us cutting downtime by even an hour pays back the effort invested in careful sourcing and QA. Every day, we field new questions from process engineers struggling with foaming, precipitation, or material loss caused by swapping grades or using poorly controlled batches. Our continuous investment in small-batch pilot testing and plant visits keeps us ahead of routine challenges and ensures our oxamic acid doesn’t just meet, but routinely exceeds, practical expectations.

    From our view, every specification, packaging tweak, and improvement in batch documentation grows from real chemistry challenges in global industries. That focus—delivering dependable oxamic acid straight from the source—sets our manufacturing apart from a world of casual intermediaries. For those who have seen the headaches of changeovers, process failures, or off-grade material, this commitment translates not just into reliability, but into trust built by everyday performance.