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Olivetol

    • Product Name Olivetol
    • Alias 3,5-dihydroxy-pentylbenzene
    • Einecs 207-334-8
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    560290

    Chemical Name Olivetol
    Iupac Name 5-pentylbenzene-1,3-diol
    Molecular Formula C11H16O2
    Molar Mass 180.24 g/mol
    Cas Number 500-66-3
    Appearance Colorless to pale yellow crystalline solid
    Melting Point 46-47 °C
    Boiling Point 330 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in ethanol and ether
    Density 1.044 g/cm³
    Odor Mild, phenolic

    As an accredited Olivetol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Olivetol is packaged in a 25g amber glass bottle with a secure screw cap and a clear, printed chemical label.
    Shipping Olivetol is shipped in tightly sealed containers, clearly labeled, and protected from light, moisture, and incompatible substances. It is packed according to regulations for chemical safety, ensuring minimal risk of leaks or spills during transportation. Appropriate documentation and hazard labels accompany the shipment for safe handling and compliance with legal requirements.
    Storage Olivetol should be stored in a cool, dry, well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizers. It should be kept in a tightly sealed container, protected from light and moisture. Proper chemical storage protocols should be followed to prevent contamination, degradation, or accidental exposure. Always refer to the Material Safety Data Sheet (MSDS) for detailed guidance.
    Application of Olivetol

    Applications of Olivetol in Industrial Manufacturing

    Olivetol has established itself as a specialized raw material in several tightly regulated industrial fields. As a primary manufacturer, we supply high-purity olivetol that meets the demands of downstream sectors. Below, we outline the principal application scenarios, covering compliance requirements, dosing guidelines, processing routes, and finished product outputs for each relevant industry.

    1. Pharmaceutical Intermediate for Cannabinoid Synthesis

    Olivetol serves as a key intermediate in the chemical synthesis of cannabinoid analogues used in the pharmaceutical sector. In particular, manufacturers use it to produce active pharmaceutical ingredients through condensation and cyclization reactions. Starting from olivetol, regulated processes yield compounds such as dronabinol and nabilone, which require precise quality and purity standards suitable for medical applications. Process control, qualified batch records, and validated cleaning are all necessary in this regulated workflow to avoid cross-contamination and ensure patient safety.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • US FDA cGMP 21 CFR Part 210/211
    • EU GMP Volume 4 Part II
    • USP Monographs for pharmaceutical cannabinoids

    Typical usage ratio

    • Used at 1.0–1.2 molar equivalents relative to isoprene reactants in the primary condensation step. Dosing optimized based on purity and yield requirements for the specific API route.

    Downstream process integration

    • Feeding into high-temperature condensation reactors after vacuum drying
    • Participating in Grignard or Friedel–Crafts reactions with alkylating agents
    • Purification via column chromatography or crystallization for API-grade output

    Final product types

    • Dronabinol (Δ9-THC) active pharmaceutical ingredients
    • Nabilone for antiemetic drugs
    • Related synthetic cannabinoid intermediates

    2. Flavors and Fragrances Synthesis

    Flavor and fragrance manufacturers employ olivetol as a precursor in producing aroma compounds featuring resorcinol moieties. Technologists rely on its phenolic structure to introduce green, herbaceous, or woody notes into finished fragrance mixtures. Precise formulation and containment procedures are critical due to its chemical reactivity and the necessity for GRAS (Generally Recognized as Safe) compliance within consumer products. Stability and purity checks take place at each synthesis step to ensure organsoleptic and safety attributes are retained throughout compounding.

    Industry compliance standards

    • IFRA Code of Practice for Fragrance Materials
    • European Union Regulation (EC) No 1334/2008 on flavorings
    • ISO 9235:2013 for aromatics in perfumery
    • FDA 21 CFR 172.515 (Flavoring substances permitted for direct addition to food for human consumption)

    Typical usage ratio

    • Introduced at 0.5–5% by weight in aroma chemical synthesis, adjusted by end aroma intensity and product matrix requirements.

    Downstream process integration

    • Undergoes alkylation, esterification, or hydrogenation to deliver aldehydes and ketones
    • Batch blending with other natural and synthetic aroma materials
    • Quality controlled for purity, trace residuals, and odor profile prior to bulk compounding

    Final product types

    • Woody or green-note perfumery bases
    • Flavor enhancers for food and beverage applications
    • Custom aroma chemicals (e.g., 3,5-Dimethoxybenzyl alcohol derivatives)

    3. Fine Chemical Synthesis for Specialty Resins

    Producers of specialty phenolic resins leverage olivetol’s aromatic hydroxyl groups in high-performance thermoset resin systems. It acts as a structural monomer, contributing to polymer backbones for advanced adhesives, coatings, and molding compounds. Resin formulators ensure that each batch meets the tight purity and moisture requirements set by downstream composite or electronics users, with outlined SOPs controlling all receiving, handling, and reaction parameters.

    Industry compliance standards

    • ISO 9001:2015 Quality Management Systems
    • ASTM D5402 (Standard Practice for Phenolic Resins)
    • REACH Regulation (EC) No 1907/2006
    • RoHS Directive 2011/65/EU for electronics applications

    Typical usage ratio

    • 5–15% by mass of olivetol within total monomer charge, optimized to achieve crosslink density and thermal properties aligned to final application profile.

    Downstream process integration

    • Introduced into polycondensation reaction vessels alongside formaldehyde and co-monomers
    • Polymerization under controlled pH and temperature conditions
    • Bulk blending and devolatilization prior to storage and shipment

    Final product types

    • Specialty phenolic resins for high-temperature adhesives
    • Coating binders for printed circuit boards
    • Compression molding compounds for automotive and aerospace parts

    4. Analytical and Research Reagents

    Olivetol finds use in academic and industrial research laboratories as a critical analytical standard and synthesis reagent. Chemists use it in cannabinoid quantification, derivatization protocols, and as a positive control for phenolic compound identification. To ensure reproducibility and traceability, stringent lot qualification, COA documentation, and controlled storage are standard. In such environments, precision dosing and the absence of trace impurities or moisture play important roles in generating reliable, publishable data.

    Industry compliance standards

    • ISO/IEC 17025:2017 General requirements for the competence of testing and calibration laboratories
    • GLP (Good Laboratory Practice) for Research and Development
    • Pharmacopoeial specifications where cannabinoids are analyzed (e.g., USP, EP)
    • Hazard Communication Standard (OSHA 29 CFR 1910.1200) for reagent labeling

    Typical usage ratio

    • Added as 1–10 mg per analytical run, or used as internal standard at concentrations of 50–500 ppm in sample matrices depending on analytical sensitivity and method validation protocols.

    Downstream process integration

    • Reconstituted in solvent systems for HPLC, GC-MS, or TLC analysis
    • Used as calibration reference in phenolic quantification methods
    • Employed as precursor in synthetic methodology development

    Final product types

    • Certified analytical standards for laboratory testing kits
    • Research-grade purity olivetol for synthetic protocol development
    • Reference materials for forensic and clinical laboratories
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    Certification & Compliance
    More Introduction

    Olivetol: A Manufacturer’s Perspective on Quality and Application

    Understanding Olivetol from the Source

    Working with Olivetol day-in and day-out teaches hard lessons about consistency, raw material purity, and what it takes to meet demanding client expectations. Here at our factory, we don’t just see Olivetol as another catalog line item. This compound, known chemically as 5-pentylresorcinol, carries a special role among specialty aromatic chemicals. We produce our model with close watch on each stage—from raw input assessment, to reaction control, to refinement. It has to fit strict industry benchmarks, but the real proof comes from downstream: whether process chemists, API developers, or flavor formulators can count on every shipment.

    Looking around the industry, Olivetol production divides into two main approaches: chemical synthesis, and plant-derived extraction. Our process uses synthetic routes, anchored in controlled reaction parameters, robust purification, and batch reproducibility. This matters because end users need predictable profiles—water content, active content, and trace impurities set the boundaries for what can, and cannot, work in pharmaceutical and fine chemical synthesis. We routinely analyze our product using HPLC, GC, and NMR. These aren’t just regulatory requirements—they reflect lessons learned from complaints, wasted time, and the cost of answering for an unpredictable lot.

    Why Olivetol Has Gained Attention

    Anyone watching specialty chemical forums or pharmaceutical news has seen Olivetol’s star rise in recent years. Several factors drive this trend. One big reason: Olivetol serves as a building block in the synthesis of cannabinoids, particularly CBD analogs and research compounds. Legal environments shift, but research markets keep growing, and so does the demand for precursor chemicals that meet both purity and traceability expectations. Beyond the pharmaceutical angle, Olivetol’s aromatic backbone positions it as a valuable intermediate for fragrances, food flavorings, and some polymer chemistry applications.

    Quality concerns affect every link in this chain. Cutting corners on solvent removal, skipping crystal washes, or letting a batch run long on reaction time will turn up later in failed syntheses or downstream OOS results. We’ve seen formulas fail over tenths of a percent in purity, and research-stage projects come to a halt from rogue isomers allowed in by imprecise separation steps. For this reason, we check every batch with spectroscopic and chromatographic tools—not because regulations demand it, but because the stories from customers make clear what can go wrong downstream.

    Direct Insights from Years of Manufacturing

    It’s easy to list technical stats: melting points, solubility profiles, and contaminant thresholds. These matter, and any serious lab expects them. Yet daily manufacturing brings home a different lesson: chemistry on paper never prepares you for scale, and paperwork rarely captures the real sources of batch variability. Over the years, we have modified our processes: swapping out early-phase reagents, upgrading stirrer assemblies, and investing in vacuum distillation that can hit ppm solvent levels.

    Even the basics make a difference. Moisture creeping in during humid months shifts crystallization; a process engineer once showed me how nothing in the documentation hinted at this risk. A modified drying protocol, using slow ramping rather than brute force, fixed this for good—at a cost of slightly longer turnaround. No customer ever regretted the improved stability and shelf life. Every adjustment comes back to one thing: the job isn’t done until predictable, high-purity Olivetol leaves the warehouse.

    Feedback—from customers and internal lab technicians—shapes ongoing tweaks. Analytical testing, beyond spec sheets, became a mainstay after one bad quarter where a series of customer complaints about off-odors exposed a micro-contaminant in our input supply chain. Tracing the source took weeks. These problems turn technical staff into investigators: those bitter lessons force us to see every raw material, every solvent, as a possible vector for downstream issues.

    Comparing Olivetol to Other Aromatic Chemicals

    Having manufactured Olivetol for years, you learn to spot both the similarities and the subtle differences from related resorcinol derivatives. Olivetol’s five-carbon side chain gives it a performance profile distinct from methylresorcinol or other alkylated phenols. The pentyl group not only impacts solubility and reaction rate in target syntheses, it also changes how the molecule behaves during purification—meaning classic crystallization routines need careful adjustment.

    Other phenolic intermediates sometimes compete with Olivetol on cost, but performance drives real-world decisions. Taking short-chain analogs often results in lower conversion rates for cannabinoid syntheses and less desirable sensory notes for fragrance formulation. This isn’t academic: one flavor house switched to a cheaper homolog and found their finished product oxidized too quickly, with customer complaints following soon after. Manufacturers at scale watch for these little shifts—quality drops don’t announce themselves on invoices, but show up in customer feedback, warranty claims, and lost contracts.

    Olivetol also stands out in terms of regulatory scrutiny. For example, downstream pharmaceutical projects using Olivetol must demonstrate traceability from batch to batch, with full documentation covering everything from metal content to allowable solvent residues. We support these requests by offering tailored CoAs, audit trails, and even third-party screening. The demands are never static: regulatory bodies have raised the bar every few years, and compliance leaves no room for shortcuts on documentation or internal QA.

    Meeting the Demands of Modern Industry

    Producers feel the squeeze from all sides. Downstream clients, especially in pharmaceuticals, ask for more than bulk shipments: they want transparency, rapid response to complaints, customizable lot sizing, and “just-in-time” delivery schedules. Our experience shows that simply producing a technically pure product won’t earn repeat business. True value comes from reliability, technical transparency, and open lines of communication with R&D staff using our Olivetol in complex synthesis schemes.

    Some of our long-term clients request specification adjustments, such as tighter controls on water content or new packaging formats. Meeting these demands requires both investment and creativity. Higher-barrier containers, nitrogen purges, and even bespoke labelling accommodate special logistics and shelf-life needs. We remember when a client’s material spoiled in tropical transit—lesson learned, and we revamped packaging protocols for warm-climate export. Every close call or failed shipment marks a turning point: once a risk surfaces, we step up our checks and address the entire shipping chain.

    Challenges Unique to Olivetol

    Making Olivetol at scale forces tough compromises. This isn’t a high-throughput commodity product—yields run lower than resorcinol or simple alkylphenols, and purification complexity can catch out anybody who tries to maximize throughput over purity. Our own output stays limited by design, since overextending runs the risk of skipping key quality checkpoints. This approach costs us in the short term, limiting extra sales, but rewards us with consistent return customers who would never risk swapping vendors after a reliable run.

    Here’s another challenge: global sourcing of reagents. Instability—currency swings, political turmoil, regional supply chain shocks—makes long-term planning complex. We’ve invested heavily in backup suppliers for critical precursors. Early in our operations, relying on single-source raw materials almost crippled a quarter’s production when an export ban upended logistics overnight. Since then, diversifying sources and building buffer stocks have kept customers insulated from market chaos.

    Analytical demands never stay static either. Customers used to order on purity percentage alone. Today, the landscape has shifted: buyers look for specific byproduct profiles, trace solvent residues, and even certifications for absence of particular allergens or heavy metals. Matching these moving targets takes constant dialogue—our technical team keeps up with regulatory alerts, while production gets in line with new standards in good time. Waiting until an official letter lands on the doorstep brings only headaches.

    From Factory Floor to End User: Lessons Learned

    Manufacturing chemicals brings daily reminders that problems travel downstream. Some of our earliest learning moments came from customer phone calls—one of which revealed a seemingly “on-spec” batch led to failed exploratory syntheses because of an unforeseen interaction with a unique co-reactant. After investigating, we discovered a trace impurity eluded standard spec checks. We adapted both our in-house analysis and supply chain management, ensuring similar issues wouldn’t slip through again. Field reports remain some of the most valuable feedback—better than any out-of-date textbook or prediction from a consultant.

    Flexibility and listening define our approach now. One leading research team asked for dozens of small-lot shipments of Olivetol on a rolling basis, with random batch audits and immediate technical backup. By working closely with them, we forecasted needed adjustments in lead time and batch documentation. These kinds of requests push us to stay nimble, adapt processes, and find efficiencies without dropping quality in the rush.

    Continuing Development—Pushing for Better Olivetol

    In an industry that moves as quickly as specialty organics, standing still means falling behind. We dedicate part of our workweek to reviewing new methodologies, updating operating procedures, and testing small-scale tweaks for process improvements. Efforts to push yield up by even a few percentage points, or to drop solvent levels further, directly support our customers’ developments in more complex chemistry and higher-value end products. Reviewing rejects and trouble batches spurs innovations; sometimes a single improvement—be it a better filter medium or a change in solvent grade—translates to measurable reductions in downstream impurity load.

    Collaborating with customers leads to more targeted solutions than working in isolation ever could. We keep technical support staff on hand to troubleshoot sticky syntheses, validate process steps, and ensure the Olivetol supplied performs predictably across diverse applications. Building this bridge between factory and research saves everyone time, budget, and frustration—a fact sometimes overlooked in a world preoccupied with catalog numbers and tick-box compliance.

    Supply chain ethics, sustainability, and working conditions represent newer areas of focus. The growing call for responsible sourcing forces us to be transparent about procurement, energy use, and waste treatment. Ongoing investment in greener synthesis steps, safer waste management, and supplier audits is no longer optional—it’s part of how we keep our commitments to clients and regulators. We see first-hand how end users build these requirements into contracts and expect us to lead, not simply react.

    Differences That Real-World Users Care About

    Customers set high expectations for Olivetol’s performance in actual use, not just on spec sheets. We hear from R&D teams who say our consistency speeds up process validation, while QA managers report fewer headaches handling incoming QC. The small differences—batch color, ease of processing, resistance to oxidation—aren’t minor when multiplied across a production run or thousands of lab hours.

    Close working relationships with technical teams reveal which “small” aspects add up. For example, a few of our early customers pushed us to screen for one particularly stubborn trace contaminant, not listed in standard compendiums. At first, this seemed an overcautious ask. In practice, regular screening prevented costly downstream troubleshooting, earning deep trust and frequent reorders.

    Unlike distributors, we control each aspect of R&D, sourcing, production, and QC. This allows us to move faster than the industry average in implementing changes, responding to concerns, or troubleshooting unfamiliar customer issues. Long-term users care about these differences—once a supplier proves attentive, transparent, and proactive, they rarely look elsewhere.

    We take pride in supporting projects with technical insight grounded in on-the-ground experience. Clients seeking Olivetol for cannabinoids, research, or materials applications want more than purity—they ask about shelf life in real-world storage, compatibility across a range of reaction conditions, and fallback strategies for outlier runs. Every customer inquiry adds to our growing knowledge, shaping how we refine both product and service.

    Supporting Innovation in a Fast-Moving Field

    Olivetol’s value doesn’t stop at purity and yield. Success in emerging fields depends on reliability, availability, and technical support unavailable from traders moving boxes on thin margin. Our direct relationships with major labs and development groups underscore this truth: feedback from their work cycles back into improvements on our end. Real innovation happens where users and suppliers stay in step, sharing challenges, and finding better results—as anyone on the receiving end of a time-sensitive shipment or a technical troubleshooting call with us will attest.

    Complex synthesis challenges—new routes to cannabinoids, alternative food flavorings, and material additives—test standards daily. Our staff get pulled into these efforts, offering insight from molecular analysis, supply chain documentation, and technical troubleshooting support. This ongoing dialogue delivers an edge customers can’t find from a rep with no factory experience or accountability to product outcomes.

    Even with increasing competition from traders touting rock-bottom prices, we see customers sticking with experienced producers who invest in process, transparency, and reliability. Having survived market disruptions, regulatory upheavals, and sudden shifts in client emphasis, we appreciate the continuing value of resilient, knowledgeable manufacturing—not just as a slogan, but as the heart of successful partnership in specialty chemicals.

    Looking Ahead: Practical Solutions for Changing Demands

    Industry requirements won’t slow down. Legal demands, new research, and consumer safety standards continue raising the bar. Our response stays grounded in hands-on improvements—whether it’s a better-controlled synthesis step, a new purification technology, or smarter packaging. Leaning on customer feedback, supplier engagement, and continual self-audit keeps us ahead of compliance trends. Sharing real-world experience, supporting transparent sourcing, and responding quickly to client needs secure the trust that commodity trading can’t match.

    Olivetol manufactures teach you that attention to detail, partnership with users, and honest communication shape product value more than technical stats alone. Producers who heed this lesson build lasting, resilient relationships—delivering not only a chemical, but confidence, reliability, and practical support for a rapidly evolving field.