|
HS Code |
512767 |
| Cas Number | 2216-52-6 |
| Iupac Name | (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol |
| Molecular Formula | C10H20O |
| Molecular Weight | 156.27 g/mol |
| Boiling Point | 212-214 °C |
| Melting Point | 42-44 °C |
| Appearance | White crystalline solid |
| Optical Rotation | [α]D20 +50° to +53° (c=1, ethanol) |
| Density | 0.9 g/cm³ |
| Solubility | Insoluble in water, soluble in ethanol and ether |
| Pubchem Cid | 16646 |
As an accredited (+)-Neomenthol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | (+)-Neomenthol is packaged in a 25g amber glass bottle, sealed with a screw cap, and clearly labeled for laboratory use. |
| Shipping | (+)-Neomenthol is shipped in secure, airtight containers to prevent contamination and evaporation. It is classified as a non-hazardous material but should be handled with care. During transit, the chemical is protected from heat, direct sunlight, and moisture, ensuring its stability and purity upon delivery. Documentation accompanies each shipment. |
| Storage | (+)-Neomenthol should be stored in a cool, dry, and well-ventilated area away from sources of ignition and incompatible substances such as strong oxidizers. Keep the container tightly closed and protected from light. Store at room temperature and avoid excessive heat or moisture to maintain its stability and prevent degradation. Follow local chemical storage regulations for optimal safety. |
Applications of (+)-Neomenthol in Industrial ManufacturingAs the direct manufacturer of (+)-Neomenthol, we supply this chiral menthol isomer for specialized industrial use. Below, we detail authentic application segments, with process data and compliance standards established from chemical and downstream industry practice. 1. Pharmaceutical Intermediate for Synthesis of Active Ingredients(+)-Neomenthol serves as a key intermediate for the synthesis of chiral pharmaceutical compounds, particularly in stereoselective reductions and asymmetric syntheses. Its optical purity and low impurity profile enable specific enantiomeric formation crucial in high-value actives. Our material integrates at the early reaction stage in bulk API production, allowing for controlled transformation in cGMP-qualified environments. Major API producers utilize this intermediate to target enantiomer-specific APIs for antispasmodics, antitussives, and topical agents. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
2. Flavor and Fragrance Compound ManufacturingPerfume and flavor compound manufacturers incorporate (+)-Neomenthol due to its distinct cooling, minty organoleptic properties, with more refined notes compared to menthol. It is used in flavor modulation for oral care, confectionery, and high-end toiletries. Downstream production applies strict raw material validation and controlled blending environments to preserve aromatic integrity, leveraging the material’s isomeric purity for flavor profile stability during thermal and pH variations in final formulation. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
3. Cooling Agent in Oral Care Product FormulationToothpaste, chewing gum, and mouth freshener producers employ (+)-Neomenthol as a cooling modifier that delivers a balanced, non-bitter taste with persistent cooling. Its stereochemistry lowers bitterness and enhances customer sensory acceptance compared to racemic forms. Used primarily in the liquid blending stage, the isomer integrates under GMP cleaning controls to avoid cross-contamination. Process validation ensures consistent dispersibility and stable release throughout shelf life, essential for regulated oral products. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
4. Cooling Sensation Additive in Tobacco ProcessingThe tobacco industry uses (+)-Neomenthol to impart a controlled cooling and mint note in reconstituted tobacco, reduced-risk products, and flavor capsules. Its unique cooling profile supports differentiation in heated tobacco and e-cigarettes versus conventional menthol. Process engineers incorporate this raw material after tobacco lamina expansion or sheet formation, under ATEX (explosion safety) and closed-system controls, due to its volatility. Precision dosing ensures regulatory compliance and uniform performance during storage and use. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
5. Aroma Modifier for Cosmetic and Personal Care ProductsCosmetic manufacturers utilize (+)-Neomenthol as a freshening agent in creams, lotions, shampoos, and shaving gels, where it offers a distinct, balanced cooling less harsh than menthol. The material’s low skin irritancy profile suits sensitive skin formulations. Quality teams carry out validated in-process controls to ensure lot-to-lot consistency and compliance with cosmetic safety standards. Formulators incorporate it during the emulsion or surfactant blending stage, where stability testing confirms fragrance retention and shelf-life requirements. Industry compliance standards
Typical usage ratio
Downstream process integration
Final product types
|
Competitive (+)-Neomenthol prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.
We will respond to you as soon as possible.
Tel: +8615371019725
Email: admin@sinochem-nanjing.com
Flexible payment, competitive price, premium service - Inquire now!
In manufacturing, details make or break a process. (+)-Neomenthol is a fine example of how subtlety in molecular structure drives very different outcomes. We have been making menthol and its isomers for decades, and over the years, our understanding of (+)-Neomenthol’s qualities has grown alongside our expertise. This compound displays its unique profile thanks to its distinct structural configuration. Unlike other menthol isomers, (+)-Neomenthol bears a shift in the positioning of atoms, which significantly changes its behavior in application—from aroma to cooling effect, even down to the type of crystallization that occurs during formulation.
We produce (+)-Neomenthol through selective catalytic hydrogenation and precise crystallization techniques to ensure a product that holds up to the scrutiny of high-end applications. Every year, downstream users—from the fragrance industry to producers of oral care solutions—ask why the distinctions among menthol isomers matter. As a chemical manufacturer, we see the simple answer in the hands-on details. (+)-Neomenthol comes as pure white crystalline solid, with high optical purity, and a gentle, less piercing menthol scent than its more famous cousin, (-)-Menthol.
Process engineers and formulators alike have learned to trust specifications earned, not just promised. Our quality control process—built from years of refining, testing, and scaling up—delivers (+)-Neomenthol with purity upwards of 99%. This purity means less unpredictability during mixing, less worry about batch-to-batch odor drifts, and fewer headaches when targeting customers who expect fine-tuned sensory experiences.
Physical properties shape work on the production floor. Melting point and volatility can impact everything from storage to dosing, especially when temperatures or handling environments fluctuate. We have tracked every complaint, question, and compliment over the years to fine-tune our product profile. The more consistent we keep the physical profile—color, melting point, and solubility—the less troubleshooting customers end up facing.
Out in the real world, (+)-Neomenthol finds its way into many products, rarely standing alone, but always imparting a clear character. In oral care, formulators turn to it for a gentle, refreshing mouthfeel without the biting sting that some menthol blends leave behind. This difference sets the stage for longer-lasting comfort, particularly in toothpastes and mouth rinses where consumer feedback punishes “burning” sensations.
The fragrance industry appreciates nuance. Some menthol derivatives push too hard, dominating softer notes. (+)-Neomenthol, with its milder cooling and less aggressive scent, blends more easily with delicate aromatics. Makers of personal care products, like deodorants and aftershaves, report fewer complications with off-notes and a more rounded finish in the end product.
Outside of personal care, food technologists in the confectionery segment use (+)-Neomenthol to sharpen or modulate flavors without creating the “menthol block” effect seen with stronger isomers. Chewing gum, mints, and lozenges all benefit from a gentle coolness that doesn’t overpower the palate. We have watched product launches flounder when formulators neglect these sensory dynamics.
Pharmaceutical applications have their own requirements. Certain topical formulations demand menthol’s cooling effect but need to avoid skin irritation or masking actives with excess scent. (+)-Neomenthol provides a balanced solution for these pharmaceuticals, delivering the desired sensation, yet reducing patient complaints related to harshness or odor.
Chemical manufacturing rarely gets celebrated for its subtleties, but the steady improvement in (+)-Neomenthol production tells a bigger story. Decades ago, natural menthol dominated, extracted from plant material that came with color, odor, and purity variations. As demand exceeded agricultural capacity and quality requirements tightened, synthetic processes showed their value. By investing in advanced hydrogenation and separation technologies, we brought about a level of control that natural extraction simply cannot match.
To outsiders, all menthol might seem interchangeable. In practice, even minor off-specification can cascade into real issues: blending inconsistencies, consumer rejection, and the need to rerun batches. Our plant teams, who live and breathe these processes every day, know the hours saved and resources conserved when each shipment holds to an uncompromising standard.
Consistency doesn’t come cheap. We have faced ingredients shortages, evolving regulatory hurdles, and the pressure to keep costs manageable without sacrificing purity. Our commitment has meant investing in robust process controls: online chromatography for in-batch monitoring, specialized filtration setups, temperature and humidity control during handling, and a laser focus on traceability.
We work closely with users to troubleshoot issues in the field—sometimes flying to customers’ plants when an unexpected result emerges. Years of feedback, benchmarking, and small tweaks in reactor or crystallizer parameters show up in how (+)-Neomenthol performs in the hands of a toothpaste formulator or a candy developer. We have seen products climb back from market rejection, thanks to a tighter spec or improved sensory match.
As chemists, our curiosity pushed us to explore the fine points among all isomers of menthol over countless production runs. Our largest competitor, (-)-Menthol, reigns as the industry workhorse, boasting a sharp, cooling punch and a distinct minty aroma. Yet, not every product benefits from such dominance.
(+)-Neomenthol stands apart in three critical ways. First, its organoleptic profile. Users describe its cooling as “rounded” or “less abrupt”—a feature highly valued in blends needing a soft hand. This quality alone has led some multinational brands to specify (+)-Neomenthol in global supply tenders. Second, its physical characteristics make it easier to handle in certain formulations where melt profile and solubility need to line up with other minor ingredients. Lastly, (+)-Neomenthol rarely brings the minor impurities that complicate downstream synthesis or create instability during storage. Only a practiced eye (and nose) can detect the difference once a finished product reaches a store shelf, but process engineers and flavor chemists appreciate it from the first blend.
Some users ask how (+)-Neomenthol compares to Neoisomenthol, Isomenthol, or Racemic Menthol. Each of these molecules holds its own peculiarities—whether it’s a pronounced bitterness, a waxy after-feel, or problems with blending in oils versus water-based carriers. Over the years, we have studied failures due to incorrect substitution. For example, isomenthol can introduce an uncharacteristic bitterness in mints, or neoisomenthol can resist blending into alcohol carriers, leading to cloudiness. (+)-Neomenthol, with its moderate sensory impact, often avoids these pitfalls.
No supplier can claim one isomer fits all needs. In our plant, we have run pilot batches to dial in the behavior of each one. Customers appreciate honest feedback: where (+)-Neomenthol works best, and where another isomer solves the problem more economically or effectively. This openness, built on trial and error and a stubborn insistence on repeatable outcomes, keeps our relationships strong and our reputation intact.
Sourcing raw materials for menthol and its derivatives used to present regular headaches. Fluctuations in feedstock purity, trace contaminants, and unexpected plant shutdowns squeezed our margins and risked disappointing customers. Our new approach blends secure supplier relationships, robust verifications, and process adaptation to navigate these obstacles. Every batch gets scrutinized for cholesterol or pesticide residues, and we have designed our hydrogenation catalysts to minimize unintended byproducts.
Sustainability runs deeper than headlines might suggest. We carry the lessons from waste management, solvent recovery, and energy use straight back into the plant floor. Several years ago, new emissions standards forced us to rethink cooling media and rework waste neutralization. Now, not only do we cut down on environmental impact, we also reclaim costs and tighten product yield. This benefits customers who face increasing pressure to ensure their ingredients come from responsible producers.
Regulatory matters only seem tedious until a slip brings real-world consequences—recalls, rejected shipments, or costly reformulations. We design our manufacturing process to align with international standards and anticipate coming requirements. Independent testing and external audits offer proof that what leaves our factory matches what customers expect. We back every shipment with a record of batch data and analytical results, not because regulations require it, but because years of partnership rely on transparency.
Safety extends beyond certificates. Our operators, trained over years with the equipment and chemistry, work under rigorous protocols. We have seen what happens if plant hygiene slips or container contamination creeps in at transport hubs. Problems never disappear with wishful thinking or clever wording. Only trust built on real performance protects a customer’s brand once the product leaves our gates.
Global markets no longer run on simple supply and demand. Customer preferences shift as quickly as regulatory goalposts. One year, natural sourcing takes center stage; the next, formulators reject allergenic risks and opt for synthetic isomers. (+)-Neomenthol’s consistent profile allows companies to pivot and innovate without unpredictable swings in product quality.
As consumer scrutiny sharpens, subtle ingredients become points of brand difference. We see our role as more than a supplier—we are technical partners, often guiding scale-up, troubleshooting new blends, or helping customers interpret current data sheets and exposure risks. Over the years, we have kept customers ahead of problems, suggesting approaches that spare them regulatory headaches or consumer backlash down the line.
No manufacturing process stays static. Each improvement comes from conversations—with R&D scientists facing an unpredictable lot, with purchasing managers pushing to keep costs steady, with brand managers who want a new sensory signature. We invest heavily in formal and informal feedback loops. Every query gets tracked, recurring issues prompt root cause analysis, and suggested tweaks earn serious consideration in ongoing plant trials.
Sometimes, a shift in product demand challenges us to rethink catalyst loadings, experiment with fractional distillation settings, or source new analytical standards. We watch for early warning signs—unusual complaints, color drifts, changes in solubility—so we can make quick adjustments. Our best innovations have come from shared problem-solving with customers who bring us into their process, trusting we understand their end goals as well as our own.
Formulating with menthol and its isomers often feels straightforward, until unexpected complications surface. Years of troubleshooting have taught us that the biggest problems often hide in the smallest details: incompatible blends, unusual precipitation, or slow-melting samples that disrupt batch flow. Customers once struggled with large menthol crystals clogging filling lines, or with “hot spots” in confections that caused uneven cooling sensations. By refining both our purification process and the way we train users on best handling practices, these incidents have become rare.
In oral care, small tweaks to the isomer balance can tip a product from “meh” to “memorable.” We advise brands to trial +)-Neomenthol alone, then in combination, so teams understand what each isomer does for flavor, cooling, and mouthfeel. Armed with this knowledge, customers blend products tailored to their region, their market segment, and their consumer profile.
Long ago, we learned that skipping this groundwork wastes time and money once a product enters the mass market. Instead, we encourage small pilots, in-person workshops, and fast feedback cycles. Our team shares decades of troubleshooting stories—hard lessons, valuable workarounds, and creative tests that save time for everyone involved, from plant operators to product managers.
Change never pauses. Product claims evolve, consumer priorities shift, supply chains get stretched. (+)-Neomenthol, once an obscure niche ingredient, has grown into a trusted solution for companies seeking a balance of cooling sensation, gentle odor, and reliable processing. As more categories—functional foods, healthcare, pet care—look for differentiated ingredients that pass both technical and sensory scrutiny, the demand for nuanced isomers will only increase.
We continue to develop production methods that squeeze more value from each run—tighter purity, better sensory matches, cleaner waste streams. The work never ends, but each success story from a customer—launching a new favorite mint, or building a toothpaste that wins over sensitive users—fuels our progress. Each batch represents more than chemical consistency; it embodies years of skill, trial, error, and a drive to make something as simple as a cooling sensation stand out.
Menthol chemistry, in all its variety, rewards those who sweat the details. For us, (+)-Neomenthol has become a symbol of what a manufacturer can achieve through steady improvement and real-world partnership, delivering a product that speaks for itself every time it meets a nose, a palate, or a skilled formulator’s hand.