Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

N,N-Methylenebis N'-1-(Hydroxymethyl)-2,5-Dioxo-4-Imidazolidinyl Urea

    • Product Name N,N-Methylenebis N'-1-(Hydroxymethyl)-2,5-Dioxo-4-Imidazolidinyl Urea
    • Alias Dimethylol dimethyl hydantoin
    • Einecs 609-246-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    843116

    Chemical Name N,N-Methylenebis N'-1-(Hydroxymethyl)-2,5-Dioxo-4-Imidazolidinyl Urea
    Molecular Formula C9H16N8O7
    Molecular Weight 348.27 g/mol
    Appearance White crystalline powder
    Solubility Soluble in water
    Cas Number 39236-46-9
    Odor Odorless
    Ph Of 1 Solution 6.0 - 8.0
    Uses Antimicrobial preservative in cosmetics and personal care products
    Storage Conditions Store in cool, dry, well-ventilated place
    Synonyms Imidazolidinyl Urea
    Stability Stable under recommended storage conditions
    Toxicity Low toxicity, may cause skin sensitivity in some individuals

    As an accredited N,N-Methylenebis N'-1-(Hydroxymethyl)-2,5-Dioxo-4-Imidazolidinyl Urea factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The chemical is packaged in a 500-gram sealed HDPE bottle with a tamper-evident cap and clear hazard labeling.
    Shipping **Shipping Description:** N,N-Methylenebis N'-1-(Hydroxymethyl)-2,5-Dioxo-4-Imidazolidinyl Urea should be shipped in a tightly sealed container, protected from moisture and direct sunlight. Handle as a non-hazardous chemical unless otherwise specified by regulatory guidelines. Transport under ambient conditions, ensuring containers are clearly labeled and compliant with applicable local, national, and international shipping regulations.
    Storage Store N,N-Methylenebis N'-1-(Hydroxymethyl)-2,5-Dioxo-4-Imidazolidinyl Urea in a tightly closed container, in a cool, dry, and well-ventilated area away from incompatible substances. Protect from moisture, heat, and direct sunlight. Use only non-metal containers if recommended, and ensure proper labeling. Keep away from acids, oxidizing agents, and strong bases to prevent decomposition or unwanted reactions.
    Application of N,N-Methylenebis N'-1-(Hydroxymethyl)-2,5-Dioxo-4-Imidazolidinyl Urea

    Applications of N,N-Methylenebis N'-1-(Hydroxymethyl)-2,5-Dioxo-4-Imidazolidinyl Urea in Industrial Manufacturing

    As a specialized manufacturer, we supply N,N-Methylenebis N'-1-(Hydroxymethyl)-2,5-Dioxo-4-Imidazolidinyl Urea for advanced industrial applications where reliable antimicrobial preservation and controlled release of formaldehyde are critical to product stability, safety, and compliance. Below, we outline its established integration across major downstream sectors, based on sector-specific formulation criteria, production processes, and regulatory requirements.

    1. Water-Based Paints and Coatings Preservation

    Industrial paint, lacquer, and emulsion producers use this compound as a formaldehyde donor preservative to inhibit microbial growth during storage and after application. Downstream formulators rely on its slow, controlled formaldehyde release to protect against bacteria, yeast, and mold contamination throughout the paint’s shelf life and in-use period, maintaining product consistency and performance under varied climatic conditions. When incorporating this raw material, dosing is adjusted based on the susceptibility of the paint matrix and regulatory thresholds, with direct introduction to the aqueous phase after pigment dispersion but prior to letdown and final thinning.

    Industry compliance standards

    • European Biocidal Products Regulation (BPR, EU 528/2012)
    • US EPA Antimicrobial Registration requirements (40 CFR § 158)
    • GB 18582-2020 Indoor Decoration Materials – Limits of Harmful Substances of Coating
    • EN ISO 11998 for wet-scrub resistance (coating durability requirements)

    Typical usage ratio

    • 0.05%–0.25% by weight of the total formula, adjusted upward for high-water-content systems or extended shelf life targets

    Downstream process integration

    • Added after pigment dispersion or during the premix stage; ensure uniform distribution before final letdown and filtration

    Final product types

    • Interior wall emulsions
    • Industrial varnishes
    • Acrylic and styrene-acrylic latex paints
    • Wood coatings

    2. Adhesive and Sealant Microbial Control

    Manufacturers of water-based adhesives and sealants utilize this compound to control microbial contamination both during bulk manufacturing and in final packaged forms. Its gradual formaldehyde release supports prolonged shelf stability and prevents bacterial or fungal degradation that leads to viscosity shifts, foul odor, and product recalls. The raw material integrates into the aqueous phase during adhesive blending, tailored in concentration to meet the demands of high-protein (casein, animal glue) or polysaccharide-based formulations.

    Industry compliance standards

    • ASTM D4236 Labeling of Hazardous Art Materials
    • EU REACH Regulation (EC) No 1907/2006 for chemical safety
    • FDA 21 CFR 175.105 (Indirect food contact adhesives, where permitted by local law)

    Typical usage ratio

    • 0.1%–0.3% as supplied, higher end for animal- or starch-based systems particularly vulnerable to spoilage

    Downstream process integration

    • Metered addition during the aqueous blending stage, before final viscosity adjustment and packaging

    Final product types

    • White polyvinyl acetate (PVA) glues
    • Cellulose-based wallpaper pastes
    • Casein-based labeling adhesives
    • Mastic sealants for construction joints

    3. Wet Wipe and Household Cleaner Preservation

    Producers of liquid-saturated nonwoven wipes and aqueous household cleaners employ this material for broad-spectrum antimicrobial protection. Its use in personal and home care products mitigates the risk of microbial contamination during storage, after opening, and throughout consumer use. The preservative dose responds to product water activity and microbial challenge test data, while the production process requires precise timing of preservative addition after cooling and before bulk filling to avoid decompositional loss.

    Industry compliance standards

    • EU Cosmetics Regulation (EC) No 1223/2009 Annex V for preservatives
    • US EPA List N for disinfectant ingredients, depending on local approvals
    • ASEAN Cosmetic Directive, Annex VI
    • China GB/T 27728-2011 for wet wipe quality

    Typical usage ratio

    • 0.05%–0.25%, modified by overall formulation water content and challenge test requirements

    Downstream process integration

    • Introduced post-emulsification and cooling, immediately before wetting of nonwovens or final filling of containers

    Final product types

    • Baby wipes
    • Surface disinfectant wipes
    • Multipurpose household cleaning sprays
    • Bathroom and kitchen liquid cleaners

    4. Leather Tanning and Treatment Solutions

    In the leather processing sector, downstream tanneries and finishing plants use this compound as a low-formaldehyde biocide in both wet-end processing and post-tanning finishes. This application targets bacteria and mold formation during hide soaking, pickling, and storage, as well as in finished leathers subject to humid shipment or warehousing. Dosage levels depend on hide thickness, water activity, and the intended leather grade, and application timing aligns with both drum treatment and surface finishing workflows.

    Industry compliance standards

    • REACH Annex XVII (formaldehyde restrictions in leather)
    • OEKO-TEX® Standard 100 module on leather goods
    • ISO 17072-2:2011 (determination of formaldehyde in leather)
    • Leather Working Group Environmental Auditing Protocol

    Typical usage ratio

    • 0.15%–0.3% based on pickling bath or finishing mixture, adjusted according to hide type (e.g. bovine, ovine) and expected storage duration

    Downstream process integration

    • Mixed into aqueous pickling or retanning solutions; optionally blended into top coat finishing baths before spraying or roller coating

    Final product types

    • Chrome-tanned leathers for footwear
    • Vegetable-tanned automotive upholstery leather
    • Upholstery leather hides
    • Finished split and grain leather articles

    5. Paper Slurry and Coated Paper Antimicrobial Protection

    Pulp and specialty paper producers add N,N-Methylenebis N'-1-(Hydroxymethyl)-2,5-Dioxo-4-Imidazolidinyl Urea to control microbiological activity in wet paper slurries and during the production of coated papers. It suppresses bacterial and fungal growth that leads to odor, slime, and paper machine fouling, ensuring paper quality, printability, and machine uptime. Typical deployment occurs at the hydropulper or coloring station and before addition of coating formulations.

    Industry compliance standards

    • US FDA 21 CFR 176.170 (paper and paperboard in contact with aqueous and fatty foods, where permitted)
    • EN 646: Determination of color fastness of dyed paper
    • ISO 8784-1: Microbial count in pulp and paper
    • China GB 4806.8-2016 (food contact paper safety)

    Typical usage ratio

    • 0.04%–0.18% on dry pulp weight, optimized for application point and temperature profile of machine run

    Downstream process integration

    • Continuous dosing into the wet end prior to sheet formation or batch addition to surface coating blends before application on size press or blade coater

    Final product types

    • Food-grade packaging boards
    • Coated art and magazine papers
    • Tissue and hygiene papers
    • Label and security papers
    Free Quote

    Competitive N,N-Methylenebis N'-1-(Hydroxymethyl)-2,5-Dioxo-4-Imidazolidinyl Urea prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    N,N-Methylenebis N'-1-(Hydroxymethyl)-2,5-Dioxo-4-Imidazolidinyl Urea: The Real-World Story from the Manufacturer’s Perspective

    Understanding the Core of Our Manufacture

    As a company that actually puts the raw ingredients in the vats, mixes by hand, oversees the fine-tuned controls, and runs every batch under our own roof, we end up with a deep familiarity with N,N-Methylenebis N'-1-(Hydroxymethyl)-2,5-Dioxo-4-Imidazolidinyl Urea. Our line workers see it develop from raw powders to a finished specialty chemical; our chemical engineers smell, see, and sometimes even taste the unmistakable characteristics of a properly run batch. The realities of scale-up, precise adjustment, and consistent output shape our daily work far beyond any theoretical formula sheet or catalog page.

    Every kilogram that leaves our facility tells a story of precise temperature control, patient compounding, and attention to keeping the final product as pure as possible. Doing the job ourselves and not outsourcing—whether to contract plants overseas or through “virtual manufacturing”—lets us vouch for what’s inside each drum. Day in, day out, we experience every challenge and improvement step firsthand.

    Product Characteristics We Know Inside Out

    N,N-Methylenebis N'-1-(Hydroxymethyl)-2,5-Dioxo-4-Imidazolidinyl Urea goes by many commercial and research synonyms and often gets grouped under the broad category of “hydantoin derivatives,” but the details in its structure set it apart from the crowd. Chemically, it combines the methylenebis linkage with imidazolidinyl urea units, one of which carries a hydroxymethyl group. Through years of running successive batches and refining filtration and reaction parameters, we noticed that this backbone creates a fine balance between water compatibility and controlled reactivity. That means its shelf life and application range also differ from classics in the imidazolidinyl urea series.

    Our production team learned early that hydrolysis control is essential. Leave the batch stirring too long, and side products build up; react too quickly at the start, and the product stays grainy and off-color. Repeated pilot runs proved that the right trick is managing subtle shifts in pH and temperature, rather than relying strictly on textbook times or ratios. Over the years, calibration after calibration, we’ve narrowed the operating window for optimum conversion and low residual monomeric sources of formaldehyde—key for clients mindful of regulatory limits.

    From our own feedback loop of batch quality checks, we keep the active hydantoin moiety at a consistent purity typically in the high ninety-percent range by HPLC analysis. We also fine-tune water content—normally monitoring to keep it below a set threshold to prevent caking on storage, based on feedback from clients working in both humid and arid climates. Real-world samples that sit on the shelf for months or get shipped across oceans bring their own surprises; by processing in our fully integrated facility, we can check each batch before it’s sealed for the road. These are all lessons that specs and data sheets rarely capture, learned on the floor, not in the manual.

    Why N,N-Methylenebis N'-1-(Hydroxymethyl)-2,5-Dioxo-4-Imidazolidinyl Urea Earns Its Role

    No catalog or outside commentary captures exactly how this molecule addresses specific chemical challenges our customers face. Unlike imidazolidinyl urea and diazolidinyl urea, this compound’s methylenebis bridge, paired with the single hydroxymethyl branch, gives it an edge in regulated environments. Strict thresholds on residual formaldehyde require consistent, low-release properties. We’ve proven through repeated analysis in our own labs and with third-party verifications that our in-house material stays comfortably within safety windows—important for anyone developing finished goods for personal care, latex modification, adhesives, or specialty paper.

    We have watched end-users switch away from simpler ureas only after fighting issues like yellowing in polymer blends, unwanted sticking during dispersion in aqueous systems, or failing regulatory clearance in tough export regions. In those instances, this hydantoin derivative stands apart through a more stable hydantoin ring system. After working through dozens of troubleshooting projects alongside technical customers, we’ve seen first-hand that unwanted crosslinking side reactions diminish with this molecule, owing to its carefully tuned reactivity and reliable, highly reproducible purity.

    Odor and color impact matters, too; those who machine, mix, and finish with these chemicals year after year can pick out which intermediates cause workroom smells or unwanted product yellowing. Our QA team—drawn from a mix of veteran production techs and analytical chemists—regularly compares internal samples against outside material and sees this class come out cleaner, more consistently white, and less prone to off-odors. The benefits show up in both small- and large-scale productions, saving clean-up and rework time for processors down the supply chain.

    Application Segments Where Experience Counts

    Decades of serving resin formulators, polymer latex suppliers, adhesive manufacturers, and specialty coatings plants have taught us that every application brings its own headaches. None of our industrial clients wants to waste time on an off-the-shelf intermediate that solves only one aspect of their process. Many came to us with hard-to-dissolve powders, or found their previous materials clumped or settled out. Hands-on experience with this hydantoin product—tested in these troublesome environments—has shown smoother integration in water-based media, owing to its distinct chemical setup.

    In formaldehyde-donating preservative applications, such as in cosmetics, cleaning agents, and specific personal care items, this compound brings flexibility that older generation preservatives simply don’t match. Our batch data shows that the methylenebis bridge provides a gentler, more gradual release profile than some linear or branched analogues. We have routinely supplied this product to those who not only demand compliance with current safety standards, but who look a decade ahead to evolving regulations on formaldehyde donors and potential metabolites.

    Manufacturers needing to balance longevity with regulatory compliance demand rigorous and honestly presented analytical data. By reporting what we find in our own labs—not simply relabeling generic third-party results—we meet their standards. The actual use feedback we receive shows strong performance in emulsion stabilization and fungistatic action, among other roles. Our technical staff regularly joins customer teams on-site to solve sticky mixing or sedimentation issues, applying direct manufacturing insight rather than off-the-shelf advice.

    Besides the technical touchpoints, application safety looms larger every year in specialty chemical circles. As governments enact tighter controls for industrial work environments and final product limits, our approach pairs production reality with up-to-date compliance. For every batch, our plant logs a unique code that’s tied to its lot’s analytical results, so any customer—or downstream user—can trace its origins and performance. Our record includes supporting plenty of risk management exercises and certification audits for our partners worldwide.

    Comparisons With Other Common Products

    One of the most frequent questions we get from on-the-ground users and R&D teams is how this product stacks up next to its better-known siblings—imidazolidinyl urea and diazolidinyl urea. In years of navigating custom orders (sometimes with a phone call at night to expedite a rush batch), we've learned the differences aren’t just theoretical. Many competing materials struggle with either moisture sensitivity or fail to maintain their composition after exposure to light or repeated heating cycles in formulation plants.

    The methylenebis linkage in this hydantoin derivative gives it a tighter lattice structure, which our tests show improves batch-to-batch consistency in diverse environmental conditions. Unlike imidazolidinyl urea, which sometimes fails shelf-life testing at higher humidity levels, our batches of the methylenebis compound withstand months of accelerated aging tests with no clumping or unusual breakdown. By managing everything in our own plant, we can tweak parameters mid-run if needed and guarantee this resilience for end-users who can’t afford process downtime.

    Diazolidinyl urea, often chosen for broad-spectrum preservative roles, generally pushes higher formaldehyde release than our methylenebis product. Years of hands-on verification, checking with both regulatory authorities and independent labs, shows our compound achieves a much lower, steadier concentration of released formaldehyde—even at higher concentrations in the final formulation. This matters to those who operate in regions with strict ingredient scrutiny, whether for import, export, or workplace safety.

    A common pain point with some urea derivatives comes during final blending and downstream production—caking, incomplete mixing, or undissolved clumps that wreck batch homogeneity. Ongoing real-world trials have given us comparative data showing the methylenebis hydantoin dissolves more uniformly and stays in suspension longer. We chart batch flow rates and look for viscosity issues in different conditions, almost always catching improvement spots at the plant before any material ships.

    Clients with large-scale runs, particularly in waterborne adhesives and specialty latex systems, mention the tendency of standard ureas to release byproducts that cloud or discolor finished products. Steady shipments of our hydantoin, checked at every stage from raw material to packaging, return fewer complaints of haze, dust, or color bleed—even after cross-country or international shipping.

    Quality Is a Daily Battle, Not an Abstract Goal

    As the actual producer, our approach to quality isn’t about certifications for their own sake, but about keeping each process reproducible in the real world. We track and chart actual in-plant process data, such as reaction temperature curves and real-time pH values, for every batch. This diligence means our technical service hotline is manned not by sales staff, but by production chemists who know what a “bad batch” looks, smells, and feels like.

    Fourth- and fifth-generation employees, who grew up on the shop floor, remember the time before digital controls, when a seasoned operator’s nose or instinct for a bubbling sound could save an entire batch. Today, we back that instinct with redundant analytical equipment—HPLC, IR, and elemental analyzers that run daily across sample points. Years of trial runs in real-world customer facilities proved invaluable in refining not just the main reaction, but the downstream drying, milling, and packaging.

    Quality improvement goes beyond a checklist. We encourage a “walk the process” mentality: regular plant tours invite both engineers and business partners to weigh in on real errors and possible upgrades. For instance, we tracked subtle off-notes in product smell back to a single mechanical gasket, which nobody noticed until a client flagged the issue. Replacing it corrected the anomaly for every batch after. Tight process control like this, honed by direct accountability, dramatically reduces the odds of recall or field failures.

    Some years ago, we invested in a full traceability system—while a costly step at first, it now pays dividends when customers need instantaneous documentation during audits or face new market regulations. Each drum or bag shipped includes a link to its analytical record, hard-won and generated through our own testing, not copied from a bulk aggregator. Close involvement of upstream sourcing gives us early warning for supply chain shifts or contaminants; decades of direct supplier relationships lets us troubleshoot before problems trickle down to batch level.

    Putting Feedback Loops to Work

    No product stays successful in industrial or specialty chemicals without a strong feedback loop. Many new buyers come to us after finding “identical” molecules sourced elsewhere perform differently in their systems. Our ongoing technical support—regular site visits, phone consults, and participation in customer plant trials—spaces out the difference daily. Patterns emerged after repeated support calls: batches from us tend to plug into existing production lines with fewer retrofits or process tweaks, saving end-users both money and uncertainty.

    Application-specific feedback led us to adjust granule size and moisture specs over the years. Technicians who blend at scale often report actual performance, not abstract numbers, and their preferences influence what we make. Uniform granule sizing came as a result of a customer in the adhesives field pointing out how uneven texture meant wasted man-hours. We listened, dialed in our dryer parameters, and recalibrated the milling step for a more consistent flow profile.

    Environmental and sustainability concerns now cut across every industry. Our real insight comes from repeated interactions with the buyers and R&D teams who must not only meet current targets, but who also plan for what’s next. Through close partnership, the feedback we bring home—on everything from unexpected by-product residues to performance in recycled paper systems—guides our ongoing process tweaks. If new regulations force a change in residual impurity levels, we run the tests, share every result, and adjust our protocol. This constant loop of improvement only happens when the actual manufacturer stands behind both the test result and the production change, not just the paper trail.

    Navigating Real Constraints: Compliance, Logistics, and Commercial Pressure

    Every year, regulatory agencies rewrite the rules on permissible additives, formaldehyde donors, and allowable impurity levels. Sitting inside the plant, we can’t afford to treat these changes as academic exercises. We’ve seen the struggles of companies burned by products that “almost” pass compliance—stockpiles wasted, recalls ordered, contracts lost. Our advantage as the producer lies in controlling every variable, letting us shift synthetic routes, refine purification, or test alternative reaction setups fast, before a deadline comes or new limits bite.

    Beyond compliance, logistics threaten any chemical supply chain. We’ve stood next to the pallet wraps during rain season, checked every seal on containers bound for ports in humid or freezing climates, and read the transporters’ notes about condensation or heat. Because we own the process, we can adapt packing or drying steps on short notice, keep stock in climate-controlled units, or expedite special shipments for repeat customers in high-risk environments. The result shows up not just in the spec sheet, but in actual usability after a month in a warehouse or two weeks on a truck.

    Price pressure remains a fact for all but the most niche specialty producers. Our stance has always been to favor long-term reliability over squeezing a penny from raw materials or cutting corners on quality checks. In a market where “identical” chemicals turn out profoundly different, our experience in running the reaction ourselves, troubleshooting actual plant problems, and responding to real end-user surprises means customers come back. They don’t buy our molecules for a logo, but for certainty that the drum shipped this month will run in their system like last month’s—and like next month’s, too.

    Looking Forward: Ongoing Advances and Shared Progress

    We don’t believe in resting on old habits, even if processes work well today. Every year brings new customer needs, technical discoveries, and environmental challenges. Scalable process improvements, new detection techniques, and safer handling protocols all spring from watching actual trends, not just reading the literature. Often, it’s a question from an experienced buyer or a plant foreman that sparks a months-long process tweak, ultimately enhancing stability or traceability.

    For instance, increasing demand for greener, lower-impact chemistry prompted us to revisit our lifecycle assessment for this hydantoin derivative. We’ve implemented process upgrades that cut waste and switched to higher-purity starting reagents from sources audited for ethical and sustainable production. These updates weren’t driven by executive mandate, but by operational feedback—and by our own conviction that better upstream control pays off for everyone in the chain.

    Our hope is that this approach—ownership of process, transparency in analysis, and readiness to upgrade with input from end-users—continues to set us apart. While shifting global trade, evolving technical demands, and unpredictable supply chain ruptures may challenge every supplier, those with hands-on production insight and willingness to adapt will stand out in a crowded field.

    Every drum that leaves our floor represents not just chemical skill, but the real-world experience of the people running the vats, sampling each batch, and listening when a client calls about their latest formulation challenge. We continue to invest in plant improvements, advanced analytical machinery, and team training to keep that drum as dependable as possible—not because we strive for standardization’s sake, but because the world’s real-world chemical users deserve more than empty promises and bare-minimum compliance.

    From our perspective, N,N-Methylenebis N'-1-(Hydroxymethyl)-2,5-Dioxo-4-Imidazolidinyl Urea isn’t just a “product” on a list: It’s the sum of years of adjustment, feedback, and shared progress with a wide range of industries and partners. We measure our work not by tonnage output, but by how often those partners thank us for solving real process problems on the ground. That’s the real story of this molecule, and why—over many years and through industry shifts—we stand behind every kilogram that leaves our gates.