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N,N'-Ethylenebisacrylamide

    • Product Name N,N'-Ethylenebisacrylamide
    • Alias BIS
    • Einecs 203-750-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    241027

    Cas Number 110-26-9
    Molecular Formula C7H10N2O2
    Molar Mass 154.17 g/mol
    Appearance White crystalline powder
    Melting Point 185-189 °C
    Solubility In Water 1.6 g/100 mL (25 °C)
    Density 1.235 g/cm3
    Boiling Point Decomposes before boiling
    Odor Odorless
    Uses Cross-linking agent in polyacrylamide gels
    Stability Stable under recommended storage conditions
    Synonyms N,N'-Methylenebisacrylamide, BIS

    As an accredited N,N'-Ethylenebisacrylamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing White plastic bottle, screw cap, labeled with product name and hazard symbols; contains 100 grams of N,N'-Ethylenebisacrylamide powder.
    Shipping **N,N'-Ethylenebisacrylamide** is typically shipped in sealed containers to prevent moisture absorption and contamination. It should be handled with care, protected from light, heat, and ignition sources. The packaging must comply with local regulations for chemicals, and shipping documentation should include hazard information. Personal protective equipment is recommended during handling.
    Storage N,N'-Ethylenebisacrylamide should be stored in a cool, dry, well-ventilated area, away from heat, moisture, and direct sunlight. Keep the container tightly closed and properly labeled. Store separately from oxidizing agents and strong acids. Avoid sources of ignition and incompatible materials. Use a chemical-resistant container and ensure proper secondary containment to prevent accidental spills or contamination.
    Application of N,N'-Ethylenebisacrylamide

    Applications of N,N'-Ethylenebisacrylamide in Industrial Manufacturing

    N,N'-Ethylenebisacrylamide is an essential crosslinking agent widely recognized for its functionality in acrylamide polymerization systems. Our facility supplies this material to industrial users in sectors with established, regulated processing technologies. Below, we present detailed real-world scenarios where our product integrates into customer value chains, supported by compliance standards, typical formulation ratios, proven downstream process stages, and finished product categories.

    1. Polyacrylamide Gel Electrophoresis for Laboratory Consumables

    This material is indispensable in laboratories for the production of polyacrylamide gels, primarily applied in protein and nucleic acid separation for diagnostic kits and research. Crosslinking properties deliver predictable gel pore structures, directly influencing the resolution and reproducibility required in clinical and research settings.

    Industry compliance standards

    • ISO 13485:2016 (Medical devices—Quality management systems)
    • FDA 21 CFR Part 820 (Quality System Regulation)
    • European Pharmacopoeia (Ph. Eur.) monographs for laboratory reagents
    • REACH Regulation (EC) No 1907/2006

    Typical usage ratio

    • 0.8–3% w/w of total acrylamide monomer content; precise ratios adjusted for target gel concentration (e.g., increased crosslinker for higher resolution needs).

    Downstream process integration

    • Dosed at the aqueous monomer mixing stage, followed by free radical polymerization initiated with ammonium persulfate and TEMED prior to gel casting in moulds.

    Final product types

    • Ready-to-use polyacrylamide precast gels
    • Protein separation kits
    • Molecular biology reagent sets
    • Electrophoresis gel cassettes

    2. Water Treatment Polymer Flocculants Manufacturing

    N,N'-Ethylenebisacrylamide acts as a crosslinker in synthetic anionic and non-ionic polyacrylamide flocculants used in municipal and industrial wastewater treatment. Its role in controlling molecular structure delivers the required mechanical and chemical properties essential for effective aggregation and sedimentation of suspended solids.

    Industry compliance standards

    • NSF/ANSI 60 (Drinking Water Treatment Chemicals—Health Effects)
    • EN 14030:2003 (Chemicals used for treatment of water intended for human consumption)
    • ISO 9001:2015 (Quality Management System for chemical production)
    • Chinese Hygienic Standard GB 27201

    Typical usage ratio

    • 0.05–0.2% relative to total monomer content, variable according to target molecular weight and desired degree of crosslinking for specific water treatment operation types.

    Downstream process integration

    • Introduced during in-situ aqueous solution polymerization of acrylamide when forming linear or crosslinked polyacrylamides before drying or granulation steps.

    Final product types

    • Granular or powdered polyacrylamide flocculants
    • Water-swellable hydrogel beads for municipal plants
    • Specialty coagulant aids for textile and paper mill effluent systems

    3. Enhanced Oil Recovery Hydrogel Formulations

    This crosslinker is key in acrylamide-based hydrogel systems used for conformance control and water shutoff in tertiary oil recovery. Its integration affects gelation kinetics, mechanical strength, and temperature tolerance, which are critical for downhole application standards and operational safety.

    Industry compliance standards

    • API RP 63 (Recommended Practices for Downhole Applications of Water-Soluble Polymers)
    • ISO 13628-6:2006 (Subsea production systems—Control systems)
    • SHE (Safety, Health, and Environmental) requirements for on-site chemical mixing operations
    • RoHS Directive (EU) for site chemical compatibility

    Typical usage ratio

    • 0.01–0.15% by mass of acrylamide monomer solution; fine-tuned based on reservoir temperature, required gel strength, and fluid viscosity profiles.

    Downstream process integration

    • Injected simultaneously with acrylamide and persulfate initiator in situ, where crosslinking sets during reservoir or wellbore polymer gel placement.

    Final product types

    • In situ oilfield conformance control hydrogels
    • Water shutoff slugs for high-permeability zone sealing
    • Pre-mixed gel pack fluids supplied for oil & gas field service operations

    4. Cosmetic and Personal Care Hydrogel Production

    Our product is used in acrylamide polymer crosslinking during the manufacture of stable, transparent hydrogels for cosmetic and personal care formulations. These hydrogels require strict control over rheology and biocompatibility, especially for direct skin contact applications.

    Industry compliance standards

    • Cosmetic Ingredient Review (CIR) standards (US)
    • Regulation (EC) No 1223/2009 (Cosmetics regulation, EU)
    • ISO 22716:2007 (Cosmetics—Good Manufacturing Practices)
    • Chinese National Standard GB 7916/2016 (Cosmetics safety technical specification)

    Typical usage ratio

    • 0.02–0.1% relative to total monomer content, adjusted based on required hydrogel firmness, clarity, and swelling behavior in the final balm or mask product.

    Downstream process integration

    • Added during batch solution polymerization after monomer dissolution, prior to initiator addition and gel casting into sheets, films, or molded hydrogel forms.

    Final product types

    • Facial mask sheets
    • Hydrogel-based skin patches
    • Blemish treating gel pads
    • Soothing eye cooling strips
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    Competitive N,N'-Ethylenebisacrylamide prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    N,N'-Ethylenebisacrylamide: Reliability in Polymer Production

    Introduction to Our Product

    For decades, N,N'-Ethylenebisacrylamide has held a unique position in our production facility. We have focused on achieving purity and consistency batch after batch. The white crystalline powder appears simple, yet inside the bag sits a hard-working crosslinker trusted in research labs, water treatment, and gel electrophoresis worldwide. Each sack we send features tightly-controlled moisture and purity standards, the result of steady investment in material handling and QA equipment.

    The Chemistry That Matters

    N,N'-Ethylenebisacrylamide, often shortened as BIS or EBAA, brings robust crosslinking to the hands of polymer chemists. Its acrylamide backbone, joined by an ethylene bridge, reacts under mild initiation to lock acrylamide monomers into a resilient three-dimensional network. We keep a close watch on critical metrics: most shipments hit 99% or better assay, and we stick to standard mesh sizes, so the powder disperses smoothly in aqueous and non-aqueous media. Ash and insoluble content run lower than market benchmarks, letting users push their polymer gels to finer tolerances or higher clarity.

    Model and Specification Choices

    We manufacture the pure form as well as tailored granularity, from extra-fine grades for rapid solution to larger particle sizes designed for slow-release kinetics. Each model has grown from direct user feedback—labs that wanted less dust with their dosing, plants that required faster flow in their batch mixing lines, research teams testing crosslinking kinetics under different shear conditions. There is no single “universal” model, so we counsel buyers based on end use, solvent compatibility, and batch size. Internal standards cover loss on drying, heavy metals, and residual acrylamide, reflecting what customers care most about, because any off-spec raw material can ripple through to final performance.

    Where This Material Shines

    In gel electrophoresis, N,N'-Ethylenebisacrylamide delivers sharper band resolution due to precise crosslink density. Our facility built out specialized cleaning lines to prevent carryover of dust or contaminants, since even minute traces can impact results at low concentrations. In water treatment, especially for municipal and industrial clients, the crosslinker assures fast, stable hydrogel formation, which helps reduce reagent costs. Every year, we hear from environmental labs that rely on our product batch consistency for trial reproducibility and reliable capture of trace organics in remediation studies.

    Key Differences from Other Crosslinkers

    Not all crosslinkers respond the same way. Unlike MBA (methylenebisacrylamide) or polyamine-based agents, N,N'-Ethylenebisacrylamide produces a flexible yet tough polymer network under a range of pH, salt, and temperature settings, with fewer byproducts. Chemically, it leaves less yellowing in polyacrylamide gels and allows for more predictable pore size control. Our production engineers keep acrylamide monomer contamination to a strict minimum, curbing background polymerization and ensuring a clean matrix. In our hands, EBAA scales up cleanly to multi-ton production without the spike in impurities found in smaller, older equipment.

    Labs often ask how our batches compare side by side with standard bisacrylamide. In real-world runs, our final material provides slightly higher gel elasticity, which means less cracking and chipping during handling. Researchers who run repetitive electrophoresis cycles, or who need reproducible high MW band separation, report fewer reruns and better yields. In our synthesis shop, small tweaks in reaction temperature and filtration make the difference, so our technical staff keep a close log of every step—from monomer charge to finished drum filling.

    Lessons from Decades on the Production Floor

    Every week, we field questions about why assay, particle homogeneity, or minor impurities matter so much. In work with agriculture clients on slow-release gels, small differences in water absorption can disrupt timing and crop yield. For those working in membrane chemistry, extraneous dust or metallic trace contamination causes downstream fouling or unwanted redox activity. In electrophoresis, minor gel haze spells extra baseline noise.

    What our experience has shown: strict process control on EBAA pays back across applications. We upgraded raw material purging and adopted low-shear blending to cut down dust, which dropped QA rejection rates by over 10%. Multiple washings and staged drying cycles solved caking complaints from long-haul users in humid climates. Each of these adjustments started with a phone call or plant visit. Our field engineers took the feedback straight to the line, and new SOPs came from watching “problem” batches go through real customer workflows.

    Solving Real-World Challenges

    Shipping EBAA in a way that keeps its quality intact during wet weather or temperature swings challenged us early on. Regular packaging couldn’t protect it from caking, so we researched multilayer liners and improved vacuum sealers. Now, bins sit dry for months in unconditioned warehouses, saving users time and rework. Our plant’s bulk handling line shifted to stainless steel and food-grade plastics, reducing regression failures in sensitive applications such as biomed materials.

    We continue seeing demand grow in the life sciences. On one example, a customer writing up a protein study credited their cleaner bands and higher yields to improved EBAA purity. In groundwater remediation, where fines or off-gassing endanger downstream units, our low-ash product clocks longer service runs and easier gel casting. End users often wonder how a “simple” crosslinker can introduce so much variability; our answer is that scale magnifies errors or flaws. Small shops focused on small lots sometimes miss these details—so at our facility, every batch earns operator sign-off and QA verification before it ships.

    Supporting Green Chemistry Initiatives

    As environmental regulation tightens, our synthesis team keeps waste output in check through solvent recycling and reductions in hazardous intermediate storage. EBAA’s main benefit in green chemistry circles comes from its high reactivity at low loading, which means less monomer feeds and shorter polymerization cycles. We are developing pilot trials that use recycled acrylamide feedstock for dedicated customers—early runs show comparable polymer network strength and clarity. The goal isn’t only lower cost, but a smaller eco-footprint for everyone using polyacrylamide gels or hydrogel beads made from our product.

    Quality Isn't Accidental

    Our process doesn’t follow generic scripts or low-cost shortcuts. It builds from a workforce that knows every valve, tank, dryer, and sieve. Between lot release and customer receipt, each shipment enters a log for traceability, letting us pinpoint any deviation before it becomes a trend. That background matters in biotechnology, where batch-to-batch repeatability can turn a failed result into a publishable outcome.

    Not all customers measure purity by the same yardsticks. Some care about loss on drying, others prioritize fast solubility or storage stability. We listen, for real, on customer calls and use those benchmarks to set our in-house specs. If a lab reports stray precipitation or plans runs in harsher conditions, we suggest bags from a lot with tighter solubility and lower trace metal readings. Feedback rounds feed directly into our next formulation review, so over time, our EBAA looks less like a generic stock chemical and more like a trusted ingredient in the user’s process.

    No Shortcuts on Safety or Compliance

    We never let a shipment leave without full documentation—COA, QA sign-off, plus SDS formatted for each receiving country. The team monitors evolving chemical handling guidance and adjusts our internal safety training accordingly. Each operator cycles through annual hazardous materials handling updates, and we supply on-premise ventilation and sealed dust transport, cutting exposure risks. Third-party audits review our safeguards annually, showing that every upgrade in upstream filtration and downstream packing can also reduce risk for handlers on the shop floor.

    Fundamentally, our approach aims at more than regulatory checkbox functions. Personnel care about leaving work safely, and we’ve had years with zero downtime for occupational incidents tied to our polymer line. That record reflects careful investment in process safety, not just on-paper rules.

    Industry and Research Partnerships

    We collaborate directly with downstream users, from university labs scaling up new diagnostic gels, to industrial water treatment facilities updating their polymer injection systems. These aren’t anonymous buyers—they’re process engineers or graduate students troubleshooting something in the field at 2 a.m. In one recent project, we worked alongside a process controls team to compare old and new granularity batches on gel performance, using side-by-side runs to resolve dosing and settling differences. The data fed into their published report, and we fine-tuned our own pulverizing phase based on their findings.

    This open-door approach makes us accountable for how EBAA behaves under real use—not just in controlled factory conditions, but in the often-messy circumstances of university research cores, crop facilitation firms, or water plants running around the clock. If a new application comes up—such as bio-catalytic gels for enzyme immobilization—we typically get early access to trial results and can collaborate to optimize future lots.

    Understanding Real Market Needs

    Our team monitors trends—in rising R&D in biomedical fields, increased demand for ecological remediation, or newer uses such as drug delivery matrices or tissue scaffolds. We stay flexible, exploring high-purity and specialty blends requested by academic and startup partners. Recent feedback called for microbead-compatible grades with extremely low extractables, so we retooled washing and sieving to hit their specs. Other users want slow-release crosslinking for agricultural moisture management; in this space, particle size and flow rate dictate performance, and our plant calibrates regular production to match those variables.

    Smaller labs sometimes worry about minimum order quantities or access to technical support. We don’t ship “one size fits all” catalogs—each inquiry gets assigned a technical staff member who can walk through viable solutions and logistics. We invite users to send back samples for troubleshooting or run reference gels using our in-house standards for benchmarking. These activities aren’t side projects; they shape future investments in process automation, new filter banks, and smarter dust-controlled packaging.

    What Sets Us Apart

    Unlike trading houses or third-party brokers, every drum, sack, and sample comes straight from our facility’s QA pipeline. We never coat or repackage old stock; instead, we retire underperforming lots and crush any returned material that strays from spec. Control over every synthesis, filtration, and packaging step builds user trust, and direct customer dialogue shows us emerging gaps. The experience our operators bring—ranging from hands-on troubleshooting in freezing northern winters to dust mitigation in wet tropical sites—forms a body of field knowledge that encodes into every new production SOP.

    Continuous Improvement Is the Rule

    EBAA isn’t a static commodity, nor do we treat it like one. Every plant audit, process tweak, and user case analysis shows ways to raise the bar: faster response to QA queries, tighter control on trace impurity loops, improved drying stages to fight caking in bulk storage. Technical staff meet weekly with downstream sales and logistics teams, feeding real feedback into the shop floor’s improvement plan. Lost time thanks to stuck product or off-grade deliveries hurts as much for us as for buyers, so the system rewards above-target batches and highlights those needing extra attention on future runs.

    As the polymer market shifts, we add new test points, run parallel pilot lines, and extend documentation to cover special customer protocols—bolstering long-term EBAA quality in every drum and batch. Our plant managers set annual investment plans based not on top-down predictions, but on the real problems and aspirations voiced by active field users.

    Wrapping up Our Perspective

    Every kilogram of N,N’-Ethylenebisacrylamide that leaves our gates contains more than a raw compound—it represents the outcome of ongoing dialogue, a drive for process improvement, and a serious duty to our partners in industry and science. As raw materials change, analytical tools improve, and global customers push for higher performance at lower environmental cost, our team’s commitment to EBAA remains constant: working closely with each user to deliver reliable, high-purity product that meets and often exceeds the demanding requirements of today’s research and industrial applications.

    We hope that this commitment shines through with every shipment, and we invite direct communication from any user looking to solve a tough production challenge, refine an experimental protocol, or simply have a supplier that listens and adapts as the market moves. N,N’-Ethylenebisacrylamide may look like another lab chemical in the inventory, but experience says it shapes the results of science, production, and environmental stewardship—one batch at a time.