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N,N'-Diethylethylenediamine

    • Product Name N,N'-Diethylethylenediamine
    • Alias DEEDA
    • Einecs 202-046-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    433571

    Chemical Name N,N'-Diethylethylenediamine
    Cas Number 100-36-7
    Molecular Formula C6H16N2
    Molecular Weight 116.21 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 157-158 °C
    Melting Point -70 °C
    Density 0.809 g/mL at 25 °C
    Refractive Index 1.437
    Flash Point 50 °C (closed cup)
    Solubility Miscible with water
    Odor Amine-like
    Pka 10.55 (approximate for the most basic center)
    Vapor Pressure 3.8 mmHg at 25 °C
    Pubchem Cid 7744

    As an accredited N,N'-Diethylethylenediamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500 mL amber glass bottle with screw cap, labeled "N,N'-Diethylethylenediamine," includes hazard symbols and handling precautions.
    Shipping **N,N'-Diethylethylenediamine** should be shipped in tightly sealed containers, away from incompatible substances like acids and oxidizers. It must be transported under cool, dry conditions with appropriate labeling. Ensure compliance with local, national, and international transport regulations. Protective packaging is required to prevent leaks and exposure during transit. Handle as a corrosive, flammable chemical.
    Storage N,N'-Diethylethylenediamine should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and incompatible materials such as strong oxidizers and acids. Keep the storage area clearly labeled and secure. Use secondary containment to prevent leaks or spills, and protect from moisture and direct sunlight to ensure chemical stability.
    Application of N,N'-Diethylethylenediamine

    Applications of N,N'-Diethylethylenediamine in Industrial Manufacturing

    N,N'-Diethylethylenediamine serves as a multifunctional intermediate and auxiliary in several industrial manufacturing fields. Its chemical properties support the production and modification of a wide range of polymers, coatings, specialty chemicals, and agrochemical formulations, enabling targeted control over end-product performance. Below, we outline its key downstream manufacturing applications, focusing on real industry practices and regulatory requirements.

    1. Epoxy Curing Agents for Advanced Resin Systems

    Manufacturers use N,N'-Diethylethylenediamine as a core component in epoxy resin curing systems, where it accelerates crosslinking reactions and enhances thermal and mechanical properties. Formulators often target rapid gel time or low-temperature cure, especially in electronic encapsulants, adhesives, and construction resins. Its high reactivity ensures swift integration into two-component or one-component formulations, supporting tight production timelines. Production teams must adjust usage based on resin viscosity and ambient curing conditions to maintain quality and workability in final products.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 for chemical use in Europe
    • RoHS Directive 2011/65/EU for electronics encapsulation
    • ISO 9001:2015 for manufacturing quality systems
    • GB 18582-2020 for coatings in the Chinese construction sector

    Typical usage ratio

    • 5–15 parts per hundred resin (phr) depending on resin type and desired pot-life
    • Dosage adjusted to ambient curing temperature and required gel time (lower temperature may require higher ratio)

    Downstream process integration

    • Incorporated during resin and hardener pre-mixing in batch or continuous mixers
    • Added to masterbatch or directly at application site for field curing systems
    • Blended under dry nitrogen to control moisture sensitivity during synthesis

    Final product types

    • Potting compounds for electronics
    • High-strength structural adhesives
    • Industrial flooring and construction coatings
    • Composite matrix prepolymers

    2. Corrosion Inhibitor Synthesis for Metalworking Fluids

    Several global lubricant and metalworking fluid manufacturers rely on N,N'-Diethylethylenediamine to synthesize ashless corrosion inhibitors and emulsifier packages. Its aliphatic amine structure allows for efficient chelation with metal cations, which helps reduce ferrous and non-ferrous metal corrosion under high-shear and aqueous conditions. The material acts as a building block in reaction steps with fatty acids or carboxylic derivatives, producing tailored amide-amines or imidazolines for robust corrosion resistance in machining and lubrication environments.

    Industry compliance standards

    • ASTM D4636 for additive performance in metalworking fluids
    • OECD Guideline No. 301 for ready biodegradability assessment
    • SAE J357 for physical properties of lubricants
    • ISO 14001 for environmental management during production

    Typical usage ratio

    • 1–6% by weight of final inhibitor formulation
    • Adjusted according to metal exposure surface area and fluid recirculation volume

    Downstream process integration

    • Reacted with fatty acids at 120–160°C with controlled agitation to produce intermediate amide structures
    • Neutralized or diluted with carrier solvents before blending into base fluid
    • Quality control checks include phase stability and metal coupon testing

    Final product types

    • Water-soluble cutting fluid concentrates
    • Neat oil-based rust preventatives
    • Grease formulations for heavy machinery
    • Temporary corrosion protection additives

    3. Polyurethane Chain Extenders for Specialty Elastomers

    Major producers use this diamine as a chain-extending agent in both aromatic and aliphatic polyurethane elastomer synthesis. It facilitates rapid molecular growth, controlled hard segment content, and improved network regularity, which are all crucial for achieving specific mechanical properties in molded goods and coatings. The diamine's relatively low molecular weight and secondary amine groups ensure precise reaction control during prepolymer and polymerization stages, minimizing off-ratio or gel formation.

    Industry compliance standards

    • EU Regulation (EC) No 1272/2008 (CLP) for chemical classification
    • FDA 21 CFR 177.1680 for polyurethane in food contact surfaces (where applicable)
    • IEC 62899 for flexible printed electronics using PU substrates
    • ISO 9001:2015 process validation for elastomer manufacturing

    Typical usage ratio

    • 0.8–1.2 equivalents per NCO group (stoichiometric, based on formulation)
    • Fine-tuned according to diisocyanate type and molecular weight of prepolymers

    Downstream process integration

    • Added to prepolymer under inert atmosphere to initiate chain extension
    • Mixed in multi-stage reactors or high-shear mixers for uniform distribution
    • Monitored using FTIR to ensure isocyanate consumption before curing

    Final product types

    • Molded elastomeric seals and gaskets
    • High-wear polyurethane rollers and wheels
    • Flexible coatings for electronic substrates
    • Industrial print rollers

    4. Pharmaceutical and Agrochemical Intermediate Synthesis

    Several upstream pharmaceutical and agrochemical companies employ N,N'-Diethylethylenediamine as a key intermediate in the synthesis of specialty active ingredients, particularly for molecules containing ethylenediamine structural motifs. Its reactivity with acid chlorides, isocyanates, and other electrophiles supports scalable production of API precursors and technical-grade crop protection compounds. Multi-step processes often utilize this diamine at critical condensation or substitution stages, enabling precise molecular modification before final API isolation or agrochemical formulation.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • 21 CFR Part 210/211 for pharmaceutical manufacturing in the US
    • GB/T 5009 Food Safety National Standard (for agrochemical use in China)
    • REACH registration as per ECHA for industrial chemical supply

    Typical usage ratio

    • Stoichiometric quantities based on desired substitution (0.95–1.05 molar equivalents relative to substrate)
    • Adjusted for reaction scale and downstream purification efficiency

    Downstream process integration

    • Introduced at condensation, cyclization, or alkylation stage in multi-step syntheses
    • Charged to glass-lined reactors with temperature and pressure control
    • Subjected to in-process analytics (HPLC, GC-MS) for intermediate verification

    Final product types

    • Pharmaceutical intermediates for antihistamines and antitumor APIs
    • Pesticide technical ingredients (fungicides, herbicide precursors)
    • Veterinary drug raw materials
    • Specialty fine chemicals for R&D synthesis
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    Certification & Compliance
    More Introduction

    N,N'-Diethylethylenediamine: A Manufacturer’s Approach to Quality and Innovation

    Understanding the Value of N,N'-Diethylethylenediamine in Chemical Production

    As a company that has spent decades in the field, producing specialized amines like N,N'-Diethylethylenediamine (often referred to as DEEDA) has transformed not only how we serve industrial customers, but has shaped our facility’s daily operations and research priorities. This diamine’s significance arises from its performance in downstream applications and the consistency it brings to our product line.

    Manufacturing N,N'-Diethylethylenediamine is not just a matter of synthesizing a base chemical. It involves a deep understanding of its nitrogens’ basicity, solubility profiles, reactivity with acylating and alkylating agents, and how it interacts in complex formulations. Our focus has always been to ensure the purity and reproducibility of each batch, because many of the clients we supply to operate under tight process controls, often regulated by international chemical standards or their own operational protocols.

    Getting the Chemistry Right: Model and Specifications

    The common molecular structure of DEEDA (C6H16N2) consists of an ethylene backbone substituted with two ethyl groups at the respective nitrogen positions. This configuration confers DEEDA its particular set of properties, such as moderate volatility, liquid state at room temperature, and solubility in both water and organic solvents. Specifications we maintain typically focus on high assay purity, water content under tight thresholds, low levels of residual mono-alkylamines, and a controlled color index to ensure downstream compatibility.

    Through continuous process improvement, like optimizing the temperature and feed rates during ethylation steps, we've brought those specification ranges closer together—minimizing product drift and process upsets. For years, batches of DEEDA in our facility have met a purity of 99% or more based on GC or HPLC analysis, something we define through rigorous pre-release testing and batch traceability.

    Real-world Applications that Drive Our Development

    Demand for N,N'-Diethylethylenediamine doesn’t arise in a vacuum. We see most volume going into the synthesis of chelating agents, pharmaceuticals, and specialty intermediates for water treatment, corrosion inhibitors, and epoxy hardeners. A good example from our own supply history: adhesive manufacturers rely on this diamine as a chain extender or curing agent due to its combination of flexibility and secondary nitrogen groups, which reduce unwanted cross-reactivity. It works in systems where monovalent or less hindered diamines risk yielding brittle products or too-rapid cure rates.

    Another area where DEEDA comes into play is in agrochemicals. By producing this material at a consistent assay, our facility helps formulators achieve the right balance between efficacy and environmental profile, especially in products that undergo further derivatization. Over the years, research collaborators have confirmed that residual amines can cause off-odors or unwanted side reactions in their synthetic pathways. Because of this, we maintain a minimum headspace for byproducts, ensuring that the manufactured lots contribute to higher yields and cleaner outcomes for our customers.

    Differentiation from Other Amines on the Market

    We’ve worked hands-on with a variety of linear and branched diamines in our reactors. N,N'-Diethylethylenediamine stands out in a number of situations where performance or handling is crucial. Compare it, for instance, with ethylenediamine or N-methylethylenediamine. Ethylenediamine, though effective as a cross-linker and chelating agent precursor, comes with stronger ammonia-like odors and a volatility that’s not always manageable on larger scales. DEEDA, with its additional ethyl groups, displays a less aggressive odor and shows improved compatibility when blended into aqueous or non-aqueous systems.

    During adduct formation, we know from long practice that the secondary amine sites in DEEDA are less susceptible to unwanted side reactions with certain epoxy and isocyanate intermediates. This translates into fewer operational headaches for our users and cleaner process vessels for plant engineers. Because our product contains a precise ethyl substitution pattern, polymer chemists gain better control over glass transition temperatures and flexibility without having to compensate for side reactions or excess chain scission.

    In trace metal chelation, the dialkyl substitution limits over-coordination that can happen with unsubstituted diamines, thereby stabilizing the final complexes to a preferred geometry. Many water treatment plants specify DEEDA because the outcomes become more reproducible in terms of both chelation efficiency and minimal formation of secondary byproducts, especially under variable pH or temperature cycling.

    Safety, Handling, and Facility Practices

    Manufacturing DEEDA at scale demands robust engineering and operational discipline. Each week, our team reviews plant data to catch any drift in the amination process or distillation runs. We keep water ingress in check at all points of storage and package transfer—years of operational experience have taught us how residual moisture can catalyze off-coloration or bump up levels of peroxidic impurities.

    Staff are regularly trained not because regulations say so, but because it builds our institutional knowledge about handling secondary amines safely: from stewardship over anti-static packaging to ensuring proper neutralization of residues during equipment flush. Over time, we’ve found these efforts cut down on corrosion inside plant pipework and incidents of off-spec batches. In case of material transfer, closed-loop loading systems and vapor scrubbers cut fugitive emissions dramatically. Facility modifications, including over-specification of stainless steel for wetted parts, mean plant downtime stays low, and both product and people remain safe.

    Supply Chain and Batch Scale-Up Considerations

    DEEDA has its quirks during scale-up. Small-lab reactors may offer more precise temperature control and rapid quench ability, but on plant scale, agitation dynamics and heat dissipation demand fine-tuning to prevent localized overheating during synthesis. We learned early on that too-aggressive ethylating conditions not only produce off-products, but also create color bodies and carbon residues that take extra operations to remove.

    We run reactor risk assessments for every new scale or process revision, involving experienced plant personnel in hazard and operability studies. This means consistency isn’t just a buzzword: it forms the basis for reliable integration into our partners’ supply chains, which often require annual volume contracts and zero unscheduled interruptions.

    Shelf stability is essential as well. Over several years of warehousing, we tracked how batches of DEEDA responded to long-term container storage. Under ambient conditions, properly sealed drums showed no meaningful loss in amine number or discoloration, enabling us to confidently ship to international destinations where transit times stretch for weeks.

    Sustainability Drivers in DEEDA Manufacture

    Like other primary and secondary amines, DEEDA production carries a responsibility toward environmental stewardship. Over time, we have increased the efficiency of our raw material use and reduced waste streams by recapturing off-gases where practical. These process improvements come from both proprietary reactor design—allowing high selectivity at moderate pressures—and careful route selection during synthesis, minimizing halogenated byproducts which complicate downstream effluent treatments.

    Our investment in on-site recycling programs allows us to recover solvents and cut disposal costs. This matters not only for our own operational budgets but also for the many Fortune 500 customers who now demand verified low-carbon sourcing from all upstream chemical inputs. Compliance with environmental criteria is no longer a checkbox exercise; it becomes woven into the manufacturing plan, from pre-treatment through finished product QA.

    Collaborating on Formulation and Problem Solving

    No two end-users approach us with the same needs. Many want DEEDA for polymer cross-linking, others for specialty resin curing, and a growing number for metal sequestration in water treatment. We have accumulated a library of case files where standard amines failed due to low selectivity or poor shelf-life, and where DEEDA succeeded instead. Our technical staff have worked closely with process chemists and plant engineers from customer teams, sharing live plant data and often running on-site trials to make sure integration proceeds without production delays.

    Over the course of one project, a large-scale pigment manufacturer experienced instability when using more volatile diamines, with recurring haze and color drift in their final dispersions. By incorporating our DEEDA, the formulator tightened their color profiles and saw downstream costs trimmed due to less frequent filter changes—demonstrating that attention to sourcing quality pays off right at the customer site.

    We encourage open technical dialogue. Real-world plant process data—whether about filtration, temperature profiles, or product purity—remains confidential, yet much of it shapes the way we advise new customers. This approach does more than foster goodwill; it builds institutional rapport, ensuring future product development takes into account what chemists and engineers see on their own lines.

    Continuous Improvement Based on Customer Feedback

    Over the last ten years, our feedback loop has grown tighter. We encourage process engineers downstream to report even minor deviations—variation in reactivity, odor, or miscibility. Every time we receive field data about an improvement or hiccup associated with DEEDA, it is shared between our R&D and operations teams. This open communication has a direct impact, guiding investments into new reactor upgrades or tweaks to purification regimes.

    A good example is the change we made to our distillation cycle to ensure water levels stay consistently below half of the previous operational threshold. That targeted reduction came straight from resin manufacturers who saw premature gelation in their lines, traced back to trace moisture. We responded with a modification to both our process and packaging, cycling batches through an additional dehydration column step followed by straight-to-sealed loading.

    These are not just marginal gains—they have allowed our partners to improve their own process economies, lengthen storage timeframes, and reduce the frequency of system cleanouts. That’s the kind of mutually reinforcing benefit that comes from genuine manufacturer-customer dialogue.

    Supporting Regulatory Compliance and Traceability

    Markets for DEEDA now face a growing raft of requirements on restricted substances, environmental reporting, and documentation. Because we manufacture, not merely trade or distribute, we trace every finished lot back to its raw inputs and document all changes in processing parameters. Regulatory agencies and large multinational clients want transparent supply chains, with full knowledge of both substance identity and impurity profiles.

    We meet these needs not through generic certifications, but through integrated batch records and long-term data retention. Our quality assurance team, experienced in industry standards and audits, works directly with clients that need full documentation for regulatory filings or internal process validations. This approach, tailored through years of experience, blends compliance requirements with operational readiness.

    These efforts come to the fore in projects where DEEDA supports regulated end-products, like agricultural chemicals or certain active pharmaceutical ingredient (API) syntheses, where elemental impurity limits or potential nitrosamine formation risk become major points of concern. By keeping our process chain both auditable and responsive, we enable our supply partners to gain regulatory approvals faster and with fewer data gaps.

    Anticipating Future Developments in Diamine Manufacturing

    The demand for higher-performance amines continues to evolve. As product purity requirements grow tighter and new applications emerge in electronics or advanced materials, our challenge as manufacturers is to tap into both legacy knowledge and ongoing R&D. Investment in catalytic improvements and green synthesis methods has increased at our facility because customers increasingly inquire about lifecycle impacts and sustainable chemistry.

    Opportunities are opening in emerging fields—battery development, functional coatings, and next-generation chelation technologies stand out as just a few areas where diamine properties like those of DEEDA play critical roles. Collaboration with academic and industrial partners shapes our priorities, from bench-scale synthesis routes to full plant production.

    Our motivation remains rooted in the real-world needs of customers—getting reliable product, with traceable quality, to users who cannot afford production downtime or unexpected reactivity due to impurity drift. As the market landscape changes, the way we make and deliver N,N'-Diethylethylenediamine adapts, guided by the practical requirements of those who use it every day.

    Conclusion: Commitment to Quality and Open Dialogue

    With every batch of N,N'-Diethylethylenediamine leaving our facility, there is a wealth of experience, technical knowledge, and customer engagement behind it. Manufacturing differs from reselling in that the risks and opportunities both sit squarely on our shoulders—the choices made on the plant floor today shape downstream success in customer operations tomorrow. By focusing on chemical quality, operational discipline, and technical collaboration, we bring real-world utility to everyone counting on this versatile diamine.