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N,N-Diethylchloroacetamide

    • Product Name N,N-Diethylchloroacetamide
    • Alias DECA
    • Einecs 205-491-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    165705

    Name N,N-Diethylchloroacetamide
    Chemical Formula C6H12ClNO
    Molecular Weight 149.62 g/mol
    Cas Number 1988-45-6
    Appearance Colorless to pale yellow liquid
    Boiling Point 215-217 °C
    Density 1.065 g/cm³ at 20 °C
    Solubility In Water Slightly soluble
    Flash Point 98 °C (closed cup)
    Refractive Index 1.453-1.455 at 20 °C
    Purity Typically >= 98%
    Odor Characteristic
    Stability Stable under normal conditions

    As an accredited N,N-Diethylchloroacetamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500 mL amber glass bottle with airtight screw cap, labeled with hazard warnings, product name "N,N-Diethylchloroacetamide," and lot number.
    Shipping N,N-Diethylchloroacetamide is shipped in tightly sealed containers, typically made of glass or high-density polyethylene, to prevent leaks and contamination. It should be stored and transported in cool, dry conditions, away from incompatible substances. Proper labeling, including hazard and safety information, is required in accordance with relevant shipping regulations.
    Storage N,N-Diethylchloroacetamide should be stored in a tightly closed container, in a cool, dry, and well-ventilated area away from incompatible materials such as strong oxidizers and acids. Avoid exposure to heat, light, or moisture. Store at room temperature, away from direct sunlight, and ensure proper labeling to prevent accidental misuse. Follow all relevant chemical safety regulations and guidelines.
    Application of N,N-Diethylchloroacetamide

    Applications of N,N-Diethylchloroacetamide in Industrial Manufacturing

    As a direct innovator and bulk producer, we supply N,N-Diethylchloroacetamide for specific industrial pathways. This material supports key chemical syntheses and downstream formulating processes, primarily as a selective reaction solvent or process aid. See below for real-world end-use applications across diverse chemical manufacturing sectors.

    1. Herbicide Intermediate Synthesis

    Chemical agro-intermediates manufacturers incorporate N,N-Diethylchloroacetamide during selective acylation steps in the synthesis of chloroacetamide-class herbicides. The molecule enhances solvation properties, stabilizes chlorinated intermediates, and allows for controlled temperature processing during the condensation of key herbicide actives.

    Industry compliance standards

    • REACH Regulation (EC) No 1907/2006 compliance for industrial use
    • ISO 9001:2015 certified manufacturing practices
    • China National Standard GB 2763-2021 on pesticide residue limits
    • United States EPA Toxic Substances Control Act (TSCA) registration

    Typical usage ratio

    • Utilized between 2–7% by weight as a process aid or stabilizer in chlorination and condensation reaction mixtures; exact dosage adjusted for solvent polarity requirements and reaction scale-up conditions.

    Downstream process integration

    • Added during primary condensation or acylation of key herbicide actives, preceding purification and formulation into technical-grade herbicide concentrates.

    Final product types

    • Pretilachlor technical concentrate
    • Butachlor active ingredient
    • Alachlor herbicide intermediate
    • Chloroacetanilide technicals

    2. Pharmaceutical API Synthesis

    Pharmaceutical chemical plants use this material as a selective acylating agent or reaction medium in the multi-step synthesis of specific APIs. N,N-Diethylchloroacetamide provides high purity solvent characteristics, supports regioselective functional group manipulation, and ensures minimal by-product formation during pharmaceutical compound assembly under cGMP-controlled environments.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • USP–NF <1058> Analytical Instrument Qualification
    • European Pharmacopoeia monographs (API-relevant)
    • FDA 21 CFR Part 211 Finished Pharmaceuticals criteria

    Typical usage ratio

    • Introduced at 1–5% by weight for API synthesis; actual ratios determined through solvent screening based on substrate reactivity and impurity profile control.

    Downstream process integration

    • Serves as the acyl donor or reaction medium during key coupling, protection/deprotection, or halogenation stages for select active ingredient manufacturing.

    Final product types

    • Pharmaceutical intermediates containing chloroacetamide motifs
    • Anti-infective drug precursors
    • Chemical building blocks for antineoplastic agents
    • Final small molecule API bulk substances

    3. Custom Fine Chemicals Production

    Specialty chemical plants apply N,N-Diethylchloroacetamide in custom synthesis routes where high reactivity acyl chlorides are generated or where precise solvation and temperature control are mandatory. It functions as both a chlorinating auxiliary and tailored solvent in non-aqueous reaction regimes, especially for custom order electronic chemical intermediates and research-scale functionalized compounds.

    Industry compliance standards

    • ISO 9001:2015 certified synthesis and QC regimes
    • SOCMA ChemStewards® responsibility code adherence
    • Japan Chemical Substances Control Law listing
    • Chinese Environmental Management Catalog for New Chemical Substances

    Typical usage ratio

    • Varies from 1–8% depending on process scale, target compound polarity, and thermal load of the reaction; small batch runs typically use higher concentrations.

    Downstream process integration

    • Employed in the initial reactive charge or as an in-situ quenching solvent within controlled batch syntheses, solution-phase functionalization, and microelectronic chemical derivatization.

    Final product types

    • Custom halogenated reagents for contract research
    • Photoinitiator synthetics for electronics
    • Specialty intermediates for polymerization catalysts
    • Analytical reference standards

    4. Polymerization Process Chain Additive

    Polymer chemical plants use this chemical as a process modifier and chain regulator in the production of specialty resins and copolymers. It supports free-radical polymerization stability, reduces unwanted cross-linking, and aids in controlling molecular weight distribution during suspension or emulsion polymer formation of engineering plastics and specialty coatings.

    Industry compliance standards

    • ISO 14001:2015 Environmental Management certification
    • ASTM D2563 Standard Guide for Assembly of High-Performance Polymeric Materials
    • EU Regulation No 10/2011 on plastic materials in contact with food
    • US EPA TSCA reporting and inventory

    Typical usage ratio

    • 1–4% by polymer batch weight, precisely measured based on monomer type, target polymerization rate, and chain transfer efficiency requirements.

    Downstream process integration

    • Introduced during monomer charging phase or after activation step; interacts with radical initiators to limit runaway polymer growth and achieve targeted copolymer architecture.

    Final product types

    • Specialty polyvinyl chloride (PVC) resin grades
    • Engineering acrylate copolymers
    • Functional polymeric coatings and films
    • Performance adhesives and encapsulants

    5. Industrial Solvent and Formulation Co-Aid

    In formulated chemical sectors, including specialty textile auxiliaries and oilfield chemical preparations, N,N-Diethylchloroacetamide acts as a co-solvent and viscosity regulator. It stabilizes active concentrations, aids in even dispersion of reactive chemicals, and offers controlled volatility to facilitate blending and process uniformity, particularly for sensitive liquid formulations.

    Industry compliance standards

    • OECD Guidelines for Testing of Chemicals
    • ISO 17025:2017 laboratory accreditation for analytical performance
    • GB/T 8286-2015 for testing textile auxiliary chemicals
    • US OSHA 29 CFR 1910.1200 for hazardous workplace chemical management

    Typical usage ratio

    • Works at 3–6% by volume in formulated liquids; level tailored depending on co-solvent blend design, end-use product viscosity, and environmental control targets.

    Downstream process integration

    • Mixed during main blending step as co-solvent or after primary solute dissolution in manufacturing of formulation concentrates, emulsifiable agents, and non-aqueous dispersions.

    Final product types

    • Textile antistatic agents
    • Oilfield demulsifier formulations
    • Flow-improving additives for petrochemical transport
    • Specialty coating agent bases
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    Certification & Compliance
    More Introduction

    N,N-Diethylchloroacetamide: Insights from the Production Floor

    How We Approach Manufacturing N,N-Diethylchloroacetamide

    Crafting N,N-Diethylchloroacetamide speaks to the collaborative nature of chemical manufacturing, where every process step builds on decades of shared expertise. At our facility, we commit to much more than churning out a simple bulk chemical. Every batch we run responds directly to the challenges we've faced in scaling up from pilot runs all the way to ton-scale production. Years in the plant have reinforced a simple lesson—consistency matters more than any brochure can express. Using a fixed-mole ratio of diethylamine and chloroacetyl chloride, we maintain narrow reaction windows and keep a sharp eye on temperature. It's not about trusting the numbers on paper, but about knowing the traits the raw materials bring to each reaction. Recipes evolve because raw material lots carry subtle differences that equipment manuals can’t predict. A dependable end product starts by accepting that N,N-Diethylchloroacetamide is sensitive to the sequence and pace of addition, not just a spreadsheet formula.

    What Sets Our Model Apart—Quality Born of Process Detail

    Our line, model DCA-320, stands as our response to industrial customers who demand purity and reliability for every lot, every shipment. It doesn’t come down to a list of specs alone. Our operators bring years of sensory experience into play: color, odor, and even how the reaction mixture "feels" in flow are evaluated. With a minimum assay of 99.5% and water content held below 0.3%, we’ve set tight thresholds that stem from actual end-use demands. We keep an eye on residual amine and acid to prevent trace-conversion side products that disrupt downstream synthesis. We don’t just trust to the lab’s GC data—field feedback from repeat customers in agrochemicals and pharmaceuticals tells us whether the batch runs as expected in a real plant. Leaks in quality show up in the field, not the spec sheet.

    Applications from the Viewpoint of the Production Team

    N,N-Diethylchloroacetamide enjoys a reputation as a specialty intermediate, showing up most often as a stabilizer or safener within pre-emergent herbicide formulations. In fields from the Mississippi to the Yangtze, it sits right at the edge of chemistry and agriculture. The molecule’s key strength is its role as an effective safener—temperatures and humidity of the growing season can swing widely, but the performance of herbicides often depends on the stability granted by additives like this. Our largest-scale buyers demand it for mixing with herbicides like acetochlor and metolachlor, both of which can stress crops if unbuffered. They’ve taught us that slight batch shifts in N,N-diethylchloroacetamide purity or trace impurity profile translate into visible effects in the field, sometimes visible in a single growing week. Overusing generic safeners can erode crop tolerance, but the right diethylamide backbone guards the active ingredient and lets farmers spend less on rescue applications.

    Differences That Matter—Why the Details Count

    The world of chemical additives includes many amide derivatives, but few parallel the role that N,N-diethylchloroacetamide has carved. Other manufacturers sometimes reach for diethylacetamide or monoethyl derivatives when diethylchloroacetamide is tight on the market. Despite what raw counts on composition might suggest, our experience tells us those alternatives quickly fall short in key applications. The difference lies in the structure: the chloro group on the acetamide actively stabilizes target herbicides against hydrolysis and thermal breakdown. We’ve fielded countless customer trials where substitution led directly to increased phytotoxicity or shelf instability. No spec can substitute for years spent working alongside users trying to stretch every application dollar.

    Compared to more basic amides, the N,N-diethylchloroacetamide molecule interacts differently with co-formulants and surfactants. The chain length and functionalization affect how well the compound mixes into concentrated emulsions. We’ve solved tank mixing issues not by changing specs but by advising buyers on differences in emulsion viscosity and solubility. The subtle interaction with water and hydrophobic actives grows critical in real-world mixing tanks. Unlike many generic additives, diethylchloroacetamide often avoids the need for co-stabilizers, which means fewer unknowns for the QA team at our customers’ plants.

    Learning from the Manufacturing Floor

    What is often left out of the standard sales pitch comes clear when manufacturing has to be scaled. N,N-diethylchloroacetamide brings hazards tied to its chlorinated structure. Each step, from handling the chloroacetyl chloride to managing byproducts, draws on hard-earned lessons about containment, reaction exotherms, and using the right engineering controls. You can’t just automate a line and expect consistent results when tiny temperature shifts spawn impurities barely detectable by routine assays. Raw materials need to be delivered just-in-time and, even more critically, kept away from excess moisture at every step. Our batch operators know that vent streams need dedicated scrubbing, not just because of compliance, but because any slip in scrubbing efficiency shows up as corrosion or odor complaints weeks later. Systems for capturing fugitive emissions and liquid waste play a larger role than the basic reaction chemistry.

    Decisions on cleaning cycles, solvent choice, and even gasket material don’t just affect costs. Teflon seals, for instance, pay for themselves when you weigh them against downtime from rubber seal degradation. The best procedures reflect experience, not just SOP checklists.

    Supporting Consistent Crop Performance

    End users farming thousands of acres don’t see molecular structures—they see how their crops respond to weather swings and input changes. Our most valued partners in agronomy count on batches that blend cleanly and store predictably, with as little drift in performance as modern chemistry allows. We monitor stability at different sitting and storage temperatures, because even short spikes in humidity or sunlight can turn a supposedly consistent additive into a liability. Therefore, we run real-world simulations on typical storage and transport, not just lab benchtop tests.

    Long-term experience shows that the only loyalty in chemistry comes from trust built over repeated, predictable outcomes. Customers often ask why their tanks foam less with our product, or why off-odors appear less frequently. We point to consistent control on residuals, and our willingness to run extended-release tests so we can spot issues before deliveries ever leave the plant. Customer field feedback sometimes proves more valuable than a folder of lab reports.

    Where Quality Really Counts—Beyond the Certificate of Analysis

    Lab technicians and QA managers often chase perfection in their chromatograms. From the perspective of our production team, however, what matters more is the batch-to-batch practical reliability. If field blenders experience clogging, off-color solutions, or unexpected reactivity, any claim of higher purity loses value. For this reason, we draw on years of trouble reports and performance trials, not just spec sheets. We build relationships with repeat bulk buyers by sharing what went wrong in previous lots—how a tighter pH control or a pre-wash on raw amine cut down problem impurities. Many years, the hardest-won improvement comes not from a new certificate but from a single change on the production line, like swapping a pump head or changing the sequence of addition.

    Quality, as we've discovered, hides in details such as tank cleaning protocols, loading order, and day-to-day calibration of meters and thermocouples. Only by walking the full path of production and testing can you see first-hand where unwanted batch variability creeps in. Chemical plant experience teaches us humility—assumptions about process steadiness often break down after midnight batch runs or during a drippy spring.

    Talking Purity and Traceability to Safety Officers and Regulators

    Modern regulation leaves little room for shortcuts in the world of amide intermediates. Safety officers regularly review our in-line data and lot traceability, often with an eye on international demand in pharmaceuticals and advanced agrochemicals. From the first raw material check-in, everything receives a unique barcode. Simple steps, such as double-checking batch logs and recording operator notes, have prevented more quality escapes than any after-the-fact investigation could manage. The value comes from an attitude where everyone on the production team owns their steps in the process. It isn’t a slogan—it’s an everyday necessity. Regulators and partners in the supply chain look over more than just finished specs; they want to see how well the team respects material and process traceability.

    While certain markets continue to chase the bottom-dollar price, our production mindset means keeping purity, traceability, and operator safety at the forefront, even when global markets feel unstable. This sometimes means running smaller batches in response to customer field complaints or dedicating extra effort to tracking small impurity spikes caused by seasonal raw material changes. These practices, sometimes viewed as burdens, actually form the backbone of a safe operation. Over the years, this commitment has earned us recognition where it matters: repeat orders, minimal incident reports, and stable business relationships built on honest reporting rather than marketing gloss.

    Ongoing Innovation Born of Field Feedback

    Much of what we’ve learned about N,N-diethylchloroacetamide never made it into printed protocols—it surfaced through feedback loops with formulators and end users facing headaches in real time. Customers report tank-mixing snags, strange precipitates on cool mornings, or changes in emulsion texture. Every cycle of learning feeds back into our process, allowing us to pin down small operational factors—such as raw material tank agitation or unexpected pressure blips—before they translate into actual defects. Over years, adjustments in distillation column settings or reconfiguring drying sections made a real impact on the clarity and stability of outgoing shipments. We’ve invested in secondary containment, tubing upgrades, and online purity monitoring not just for compliance but to respond directly to what growers and blenders actually face at the farm level.

    That openness to improvement reflects why many customers stick with us even as other suppliers pitch new alternatives. Fast responses to customer stories of failures—backed by willingness to investigate and adapt—turns a simple intermediate into a backbone component of reliable formulations.

    Why Reliable Supply Matters in Industrial Chemistry

    Agrochemical firms and pharmaceutical producers manage complex timelines. Disruptions in the additive chain have far-reaching consequences. In recent years, pandemic interruptions and logistical bottlenecks exposed industry fragility. Our approach means we’ve diversified raw material sources, expanded our in-house blending and packaging lines, and run scenario-planning for everything from port closures to raw material contamination. Our storage tanks sit with real-time temperature and level monitoring, reducing chances of accident or costly spoilage. Direct relationships with logistics partners let us react early to weather events or shipping delays. All these actions come from living day-to-day with chemical supply, not just filling out orders. In the end, reliability grows not from promises but from every member of the manufacturing and logistics team putting in the extra checks, even when the warehouse looks calm.

    Growing Global Expectations, Evolving Best Practices

    The growth of globalized agriculture and advanced pharma raises the bar for chemical intermediates like N,N-diethylchloroacetamide. Supply chain traceability and anti-counterfeiting tools sit side by side with quality metrics in modern tenders. European and North American customers push for ever-stricter control of residuals and contaminants, reflecting rising environmental and regulatory awareness. Reports of product recalls due to hidden impurities or cross-contamination push producers to go beyond simple compliance. Many manufacturers try to answer demands through automation alone, but our experience tells us that operator training and open communication prevent more errors than HMI alarms.

    Sustainability goes beyond energy usage and solvent recovery. We recycle waste streams wherever possible, and work closely with third-party auditors who inspect our facility and documentation annually. Years of this discipline have proven that external eyes and frank internal reviews sustain improvements more than any one-off investment. The focus on impact—on both field performance and environmental burden—keeps the whole team engaged and alert.

    Addressing End-User Pain Points Directly

    Growers and processors face unique headaches that theory seldom covers. Some want to know why batch odor has shifted since last season, or why shipment viscosity changes in the middle of a contract. Our customer service reps don’t dodge technical queries; they tap into the plant’s day-to-day logbooks and involve those who ran the actual batch. That open book approach wins repeat business because it respects the real world unpredictabilities faced in blending, spraying, and shelf storage. We don't just file away complaints; we feed them back into process review alongside operator insights. Solving a field compatibility issue sometimes boils down to changing a filtration step or requesting a different drum type for overseas freight. These fixes grow from hands-on teamwork, not just contractual obligation. Over time, this spirit of attention to detail does more to prevent big failures than any legalese ever written.

    Cooperation Across Industries Keeps Us Focused on Improvement

    Interactions with colleagues in downstream chemical, seed, and crop companies create a constant stream of suggestions and pain points. We welcome audits, facility visits, and collaborative troubleshooting because improvement comes from many sources, not just our own walls. Specialist teams from customers' end regularly walk through our tanks and lines, discussing blending, emissions, and even the finer points of drum cleaning. Each perspective helps us improve outcomes. We’ve found that collaborative work on joint field trials, testing alternate delivery solvents or shelf life extenders, produces more robust solutions than working in isolation. Multi-party engagement increases the odds that our N,N-diethylchloroacetamide continues to perform where it matters.

    Looking Ahead: Challenges and Opportunities We See for N,N-Diethylchloroacetamide

    Global chemistry and agriculture face rising pressures—from regulatory tightening, environmental scrutiny, and more extreme weather. N,N-diethylchloroacetamide will continue to matter as long as herbicide and pharmaceutical reliability depend upon thermal and hydrolytic stability. Our focus stays trained on adjusting to shifting raw material availability, new regulations, and the real, evolving needs of field users. Improvement often starts inside the plant, with training and small process tweaks, but expands outward through ongoing relationships with buyers and partners.

    Future opportunities rest on sustainable sourcing and the reduction of hazardous side streams. We are investing in process R&D and cleaner catalyst systems, aiming to both improve yields and further cut both waste and emissions. Our priorities reflect the lessons earned by everyone who has ever set a hand or an eye on the production line, not just the figures in a quarterly report. N,N-diethylchloroacetamide delivers value only because of the collective knowledge and commitment running through every facet of its manufacture and distribution.

    Our Commitment to Every Batch—Experience and Transparency

    Over years of experience in making N,N-diethylchloroacetamide, we've learned the true cost of short-cuts and hidden mistakes. Expertise means more than technical mastery; it means a willingness to admit errors, accept feedback, and use every disappointment to improve for the next batch. We operate on a principle that the best chemical is one that works right in the hands of every farmer, formulator, and field chemist. That means transparency in every production step, openness during customer visits, and honesty in handling issues that arise during transport, storage, or application. No certificate or marketing campaign can substitute for the trust earned by steady, reliable performance and a willingness to engage directly with every customer question or challenge.

    This spirit guides our plant floors, shapes our operator training, and defines every bottle or drum that leaves our loading dock. Looking ahead, we remain committed to building on experience, supporting innovation, and delivering N,N-diethylchloroacetamide with all the reliability and care that our industry demands.