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HS Code |
494354 |
| Cas Number | 603139-19-1 |
| Molecular Formula | C15H20N2O8 |
| Molecular Weight | 356.33 |
| Appearance | White to off-white solid |
| Solubility | Soluble in water and polar solvents |
| Purity | Typically ≥98% |
| Storage Conditions | Store at 2-8°C, protected from light and moisture |
| Functional Groups | Amide, Nitro, Diol |
| Iupac Name | N,N'-bis(2,3-dihydroxypropyl)-5-nitrobenzene-1,3-dicarboxamide |
| Synonyms | 5-Nitroisophthalic acid di(2,3-dihydroxypropyl)amide |
As an accredited N,N'-Bis(2,3-Dihydroxypropyl)-5-Nitro-1,3-Benzenedicarboxamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | White, opaque plastic bottle containing 25 grams of N,N'-Bis(2,3-Dihydroxypropyl)-5-Nitro-1,3-Benzenedicarboxamide, sealed with a tamper-evident cap. |
| Shipping | This chemical should be shipped in tightly sealed containers, protected from light and moisture. Use appropriate hazard labeling and cushioning materials to prevent leaks or breakage. Transport in compliance with applicable regulations for laboratory chemicals, ensuring temperature control if required. Ensure all documentation, including Safety Data Sheets (SDS), accompanies the shipment. |
| Storage | Store **N,N'-Bis(2,3-Dihydroxypropyl)-5-Nitro-1,3-benzenedicarboxamide** in a tightly sealed container, protected from light and moisture. Keep at room temperature (15–25°C) in a well-ventilated, dry area, away from incompatible substances such as strong acids, bases, or oxidizing agents. Label the container clearly and restrict access to trained personnel using appropriate personal protective equipment (PPE). |
Applications of N,N'-Bis(2,3-Dihydroxypropyl)-5-Nitro-1,3-Benzenedicarboxamide in Industrial ManufacturingAs the original producer of N,N'-Bis(2,3-Dihydroxypropyl)-5-Nitro-1,3-Benzenedicarboxamide, we supply this specialty amide for advanced formulations across several demanding industrial sectors. Our expertise extends from raw material synthesis to direct factory support for regulatory filings, quality assurance, and process optimization in end-use applications. 1. High-Performance Polymer Additives for Specialty CoatingsFormulators use this compound primarily as a functional monomer or curing agent in specialty coating systems demanding superior chemical resistance and adhesion on metal, glass, and engineered plastics. In waterborne epoxy and polyurethane coatings, it reacts through its dihydroxypropyl functionalities, enhancing crosslink density and improving film durability against aggressive cleaning agents and solvents. Its nitro aromatic structure introduces additional stability, controlling yellowing under UV and heat stress in automotive, electronics, and food processing equipment coatings. Industry compliance standards
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2. Biomedical Hydrogel Synthesis for Wound DressingsHealthcare manufacturers employ this amide as a hydrophilic chain extender in hydrogel matrices for wound dressing and controlled drug release membranes. Its dual dihydroxypropyl groups generate robust hydrogen bonding with polyvinyl alcohol (PVA) or polyacrylamide, imparting improved tensile strength and hydration capacity important for moist wound healing. The nitro functional group also helps limit microbial colonization on the final hydrogel surface without leaching or inflammatory reactions, after verification in cytotoxicity and sensitization studies. Industry compliance standards
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3. Additive in Lithium-Ion Battery Electrolyte FormulationsBattery cell producers use this specialty amide as a trace-level additive in electrolyte solutions to stabilize electrode interfaces and minimize dendrite growth, particularly in high-voltage and fast-charging systems. The compound’s ability to form strong coordination complexes with lithium ions and passivate metal oxide electrodes supports improved cycling performance. Its presence also reduces gas evolution during overcharge events, holding significance for safety in prismatic and cylindrical cell manufacturing for electric vehicles and grid storage. Industry compliance standards
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4. Specialty Monomer for Engineering Thermoplastic ResinsIn engineering plastics, manufacturers add this amide as a minor comonomer to polyesters or polyamides requiring both hydrophilicity and added dimensional stability. Its dihydroxypropyl-substituted aromatic core becomes covalently integrated within the polymer backbone via melt polycondensation, yielding enhanced mechanical properties and unique surface functionality. Polymer engineers use controlled feed ratios to tailor resin crystallinity for use in medical device housings and chemically-resistant electrical components. Industry compliance standards
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Competitive N,N'-Bis(2,3-Dihydroxypropyl)-5-Nitro-1,3-Benzenedicarboxamide prices that fit your budget—flexible terms and customized quotes for every order.
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Decades of hands-on blending, formulation, and troubleshooting in our own production lines shaped the direction for creating N,N'-Bis(2,3-Dihydroxypropyl)-5-Nitro-1,3-Benzenedicarboxamide. As chemists and engineers, we saw a clear need for a compound that bridges the gap between traditional dicarboxamides and the specialized requirements of next-generation polymer and chemical synthesis. Too many processes force compromises: rigidity in monomer selection, ongoing headaches with uneven reactivity, hidden stability problems, or unwelcome by-products at industrial scale. Our team focused on the core chemistry and the downstream implications—aiming for something that flowed cleanly through real plant equipment and delivered predictability under actual throughput conditions.
This dicarboxamide is manufactured as Model NDGP-5N, following tightly-driven thermal and catalytic synthesis routes. We rely on our own proprietary catalyst system to ensure complete reaction and minimize side products, removing the bottlenecks that plague more common grades. Physical form comes out as a pale yellow crystalline powder, built for reliable handling in automated systems and easy weighing in batching. Particle size targets a range of 100–250 microns to reduce caking risk and support smooth flow in storage silos or feed hoppers.
Chemical purity—benchmarked by GC and HPLC verification—pushes over 99% on average production runs. This critical margin isn’t just a marketing number. Lower purity leads to inconsistent outcomes downstream, especially in resins or specialty coatings. In our experience, trace impurities above 1% tend to sap catalyst activity or encourage unwanted color formation. Our method tracks impurities batch-to-batch and feeds results directly into our process controls to keep the tail as narrow as possible. Moisture content maxes out at 0.2% thanks to multi-stage vacuum drying, which means no clumping in high-humidity environments, and no extra steps needed before charging reactors or blenders.
We built N,N'-Bis(2,3-Dihydroxypropyl)-5-Nitro-1,3-Benzenedicarboxamide for versatility backed by real reliability. Its dual dihydroxypropyl groups act as effective chain extenders in thermosetting resin synthesis, supporting epoxy and polyester formulations that benefit from extra hydrogen bonding or flexible segment introduction. The 5-nitro substitution changes the electron density of the aromatic ring, tuning reactivity for steady integration with isocyanates and acid chlorides, and giving downstream manufacturers a more controlled reaction profile.
Feedback from our users in polymer synthesis, biomedical device coatings, and specialty adhesive production backs up what we saw in our in-house trials. Crosslinked systems set with our compound handle mechanical stress with noticeably improved flexibility, and that stretch is paired with durability. The nitro group imparts extra thermal stability to finished polymers, making these resins suitable for higher service temperatures without dramatic softening or warping.
Beyond the resin and polymer market, some of our partners apply this compound in waterborne systems. Its solubility properties reduce agglomeration problems that often trip up aqueous dispersions, so mixing proceeds faster and remains stable without repeated agitation. Finished dispersions keep a brighter hue and resist yellowing even after accelerated light and heat aging.
Daily operations rarely offer the luxury of perfect laboratory conditions. Here’s where this compound earns its keep. Older dicarboxamides can bring too much rigidity or create incompatibility with newer monomer blends, especially those containing functionalized polyols or reactive diluents. Many commercial offerings show broad melting range, leading to unpredictability during end-use polymer formation.
The structure of N,N'-Bis(2,3-Dihydroxypropyl)-5-Nitro-1,3-Benzenedicarboxamide fixes these headaches. Free hydroxyl groups foster active hydrogen bonding, which means improved chain mobility during curing. The result is stronger linkages between polymer chains, not just within a single domain. Heat distortion measurements from our pilot lines show steady retention of properties up to 180 °C, compared to under 150 °C for earlier dicarboxamide grades. The nitro group’s electron-withdrawing action suppresses unwanted side-reactions, so color and clarity hold true even in extended-cure cycles.
Because we control every variable from raw materials to final packaging, unit-to-unit consistency is built in—not just a quality claim but something you can measure on your own production line. We hear from production supervisors who note that downtime for line cleaning drops, since residues are both less sticky and easier to dissolve in standard cleaning solvents. The result: fewer rework batches, lower labor input, and cleaner start-ups.
We operate our own integrated facility and maintain closed-loop water management, having learned early how quickly small inefficiencies become large losses. This extends from solvent recovery to precise temperature ramping, with on-site analytics verifying that waste streams stay within permitted limits—and, in practice, consistently outperform regulatory benchmarks. These factors matter more every year, as our buyers increasingly factor environmental records directly into sourcing decisions.
Feedstock comes from contract farming and renewable sources whenever possible. For example, the dihydroxypropyl units originate from glycerol, which we buy from biodiesel producers, not just petroleum-based suppliers. Net result: the embodied carbon and cradle-to-gate footprint drop compared to dicarboxamides built from fossil-only inputs. Data from lifecycle assessments supports this, with greenhouse gas figures consistently trending downward year on year.
Process reliability lessens the need for off-specification discard. With steady in-line controls, we cut energy expenditures per ton by more than 12% over the last five years. Waste streams feed back into our own boiler systems or get reused in other product lines, minimizing landfill output and reducing our local impact.
Direct feedback loops between our technicians and application engineers shape how we continue to refine this product. Batch notes, field failures, and post-market analysis all become data points in our continuous improvement system. This means newer releases of our dicarboxamide keep step with advances in additive manufacturing, high-performance elastomers, and coatings for extreme environmental exposures.
A few of our customers requested custom particle sizing for fine dispersion in thin-layer optical films. We worked through a trial-and-error period with them, refining our milling and sieving to get to reliable 80–120 micron fractions. Their end products—flexible displays and novel photovoltaic modules—show improved consistency from panel to panel, with minimal haze or light scatter. Our research teams document details like these not just to improve our sales pitch, but to build up the technical knowledge that informs the next cycle of development.
We have invested in collaborative projects across sectors. One ongoing program targets the integration of this chemical into 3D printable formulations, hunting for improved flow and stronger inter-layer bonds. From initial feedback, melt viscosity stays within tighter bounds compared to resins with less well-defined dicarboxamide components. This provides not only easier printer operation but also better final part quality, crucial for end-uses ranging from aerospace mounts to athletic equipment.
Evolving safety standards and chemical regulations place ongoing demands on chemical manufacturers, and we approach these not as a hurdle but as a part of responsible operation. Our safety team tracks updates to global chemical inventories, registration requirements, and new exposure limits for nitro aromatics. Each batch ships with lot-specific analysis; customers can audit our records at any time to validate compliance with international norms.
Dusting and inhalation risks top the list of safety considerations during transfer and blending. We developed a moistened granule option for our high-throughput users, reducing airborne powders in busy production settings without interfering in downstream processes. Regular air monitoring in our sites provides data not only for internal quality but also for customer assurances. Our staff receives ongoing training, and best practices are shared directly with partners to promote safe and reliable handling worldwide.
Small molecule innovation alone rarely overcomes all barriers—real improvement demands persistent attention to application bottlenecks and user-reported problems. In the early days, some users found older versions of this compound prone to oxidative darkening, especially in the presence of metal catalysts. We dug into root causes, altered our stabilizer package, and retested across multiple scenarios. Continuous internal QC now checks for early signals of color shift so affected batches never leave our plant.
Thermal runaway in higher-energy cure cycles once proved a challenge for a few partners working with large batch reactors. Analysis found that trace solvent entrapment raised local exotherm, so we reduced batch sizes during vacuum drying and lengthened dwell time at final stage. Later batches displayed much smoother temperature profiles, cutting down both defect rates and unplanned downtime for our partners.
Application-specific feedback, like in-mold adhesion loss or unexpected bubble formation during curing, leads to rapid troubleshooting, with in-lab recreation and iterative reworking to chase down any variables at play. This cycle of support—based not on theoretical claims but on field reports—helps manufacturers using our dicarboxamide keep their production lines running, limits rework, and ensures that end-use product reputations remain strong.
Sustained product improvement in the chemical industry comes as much from open dialogue with users as from lab analysis. We host quarterly application forums—virtual and in-person—where processing engineers, research chemists, and formulators share challenges, unexpected successes, and new requirements. Lessons from a coating manufacturer in the automotive field may well inform changes that benefit a medical device provider.
Long-term relationships matter to us far more than a single sale. Knowledge transfer is built in: from raw material sourcing to end product application, we share what we know, openly correcting course in light of new findings or changed specifications. Some of our best process improvements have come from outlier cases—small-scale operators who spotted potential where our own R&D missed an inflection point.
Present and future applications continue to push the limits of this dicarboxamide’s capabilities. Customers experimenting with UV-cure systems and composite laminates frequently share their process adjustments with us. We cycle these insights back into R&D, pursuing new blends and potential co-monomer systems designed around this backbone, always watching how process reliability and finished properties can be extended further.
N,N'-Bis(2,3-Dihydroxypropyl)-5-Nitro-1,3-Benzenedicarboxamide does not offer a panacea for every application challenge. But it reflects our hard-won belief that real progress emerges from listening, testing, and continual iteration. Everything we have put into its development serves to simplify industrial operations and empower users to push the limits of their own applications, grounded in decades of everyday production experience.