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N-Methylimidazolium Hydrogen Sulfate

    • Product Name N-Methylimidazolium Hydrogen Sulfate
    • Alias [NMIM][HSO4]
    • Einecs 629-733-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    462780

    Chemical Name N-Methylimidazolium Hydrogen Sulfate
    Molecular Formula C4H8N2O4S
    Molecular Weight 180.18 g/mol
    Appearance Colorless to pale yellow liquid
    Density 1.20 g/cm3 (approximate)
    Melting Point Typically below room temperature
    Boiling Point Decomposes before boiling
    Solubility In Water Highly soluble
    Ph Acidic
    Cas Number 262297-13-2
    Storage Temperature Room temperature
    Refractive Index 1.485 - 1.495
    Odor Odorless or faint amine-like
    Stability Stable under normal conditions
    Conductivity Ionic liquid with high conductivity

    As an accredited N-Methylimidazolium Hydrogen Sulfate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of N-Methylimidazolium Hydrogen Sulfate supplied in a sealed, labelled, amber glass bottle with hazard warnings and safety data.
    Shipping N-Methylimidazolium Hydrogen Sulfate should be shipped in tightly sealed containers, clearly labeled, and protected from moisture and incompatible substances. Transport according to local, national, and international hazardous goods regulations. Use appropriate cushioning and secondary containment. Ensure Material Safety Data Sheet (MSDS) accompanies the shipment for emergency and safety reference.
    Storage N-Methylimidazolium Hydrogen Sulfate should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from moisture, heat sources, and incompatible materials such as strong bases and oxidizing agents. Avoid exposure to direct sunlight. Always label the container clearly and use appropriate secondary containment to prevent leaks or spills.
    Application of N-Methylimidazolium Hydrogen Sulfate

    Applications of N-Methylimidazolium Hydrogen Sulfate in Industrial Manufacturing

    N-Methylimidazolium hydrogen sulfate serves critical functions in several advanced industrial sectors due to its ionic liquid properties, thermal stability, and strong Brønsted acidity. Our material supports high-value manufacturing processes where efficiency, selectivity, and safety standards demand precision in formulation and integration. Below we outline specific documented applications across real downstream fields, providing technical details on compliance, dosage, process usage, and end product outcomes.

    1. Catalytic System for Cellulose Hydrolysis in Biomass Refining

    This ionic liquid acts as an acidic catalyst and solvent phase for depolymerizing lignocellulosic materials. Industrial processors use it to dissolve cellulose fibers and promote hydrolysis in large-scale biorefinery operations aiming to convert biomass into fermentable sugars. Key applications include advanced biofuel production and specialty sugar derivatives, where the ability to recycle the ionic liquid boosts process economics and environmental safety. Formulators optimize concentration based on feedstock reactivity and targeted depolymerization rates, matching the requirements of continuous reactor designs.

    Industry compliance standards

    • ISO 14001 Environmental Management Systems
    • European Union REACH Regulation for chemical use in biomass processing
    • EN 16575 for sustainability criteria in bio-based products
    • United States EPA Clean Air Act limits on process emissions

    Typical usage ratio

    • 15-30 wt% relative to dry cellulose mass, adjusted per substrate crystallinity and reactor throughput

    Downstream process integration

    • Recycled in situ within hydrolysis reactors after solid-liquid phase separation
    • Mixed directly with shredded biomass at the initial pre-treatment stage
    • pH and water content monitored for catalyst performance maximization
    • Undergoes regeneration cycles before periodic replacement

    Final product types

    • Fermentation-ready glucose syrups
    • Bio-based ethanol and butanol intermediates
    • Cellulose-derived fine chemicals
    • Oligosaccharide blends for food and pharma

    2. Acidic Catalyst for Esterification in Biodiesel Synthesis

    Downstream biodiesel manufacturers employ this ionic liquid as an acid catalyst for the esterification of free fatty acids present in waste oils or low-grade feedstocks. The high acidity, reusability, and low volatility reduce hazardous emissions compared to traditional mineral acids. Manufacturers achieve consistent methyl ester yield, especially from high FFA feedstocks such as waste cooking oil, as the catalyst enables simultaneous transesterification and esterification when integrated into multi-phase reactors. Detailed monitoring of ratio and residence time allows for high conversion while maintaining compliance with international fuel quality standards.

    Industry compliance standards

    • EN 14214 European Biodiesel Standard
    • ASTM D6751 Standard for Biodiesel (USA)
    • GMP+ Feed Safety Assurance for co-products
    • Local wastewater and emission controls (IEA Bioenergy Task 39)

    Typical usage ratio

    • 2-5 mol% relative to total acid content, optimized for oil acidity and batch or continuous process

    Downstream process integration

    • Fed directly into pre-reactor esterification units prior to transesterification phase
    • Recycled through product and glycerol separation for multiple cycles
    • Dosed after inline acidity measurements
    • Neutralization and recovery step after batch completion

    Final product types

    • Biodiesel (Fatty Acid Methyl Esters)
    • Purified glycerol
    • FAME blends for automotive and industrial engines
    • Biodiesel co-products for surfactant and detergent manufacturing

    3. Electrolyte Additive in Metal Electrodeposition (Electroplating)

    N-Methylimidazolium hydrogen sulfate is utilized as an ionic liquid electrolyte or additive in advanced metal electrodeposition processes, primarily for plating aluminum, copper, and tin alloys. Industrial platers achieve precise metal distribution, brightening effects, and improved adhesion due to low vapor pressure and high electrical conductivity. Experts adjust additive ratios based on specific metal being deposited, current density, and component geometries. The resulting reduction of hydrogen embrittlement and enhanced environmental profile compared to cyanide-based systems drive usage in electronics and aerospace plating.

    Industry compliance standards

    • RoHS (Restriction of Hazardous Substances Directive) for electronics coating
    • IEC 62321 Material Declaration Standard
    • ISO 12683 for electrodeposited coatings on engineering components
    • REACH authorization for plating chemicals

    Typical usage ratio

    • 10-40 vol% in mixed ionic liquid/water electrolyte bath, tailored by plating metal, current density, and targeted coating thickness

    Downstream process integration

    • Poured into anode-cathode plating baths prior to substrate immersion
    • Controlled via inline conductivity and bath temperature probes
    • Regenerated or filtered out at maintenance intervals
    • Integrated in closed-loop bath recirculation systems

    Final product types

    • High-reliability circuit boards
    • Precision aluminum or copper contacts
    • Decorative and corrosion-resistant plated fasteners
    • Electronic connector pins for aerospace and telecom

    4. Solvent Medium for Organic Acid Catalysis in Pharmaceutical Synthesis

    Pharmaceutical manufacturers incorporate this ionic liquid as a reaction medium for specific organic acid catalyzed processes, including acidolysis and Friedel–Crafts acylation reactions. Its non-volatile, thermally stable profile meets GMP demands for minimized solvent loss and higher API yield. Experts define concentration and recovery based on synthetic route, regulatory status of process aids, and target molecule stability. This approach often facilitates challenging reactions or allows removal of volatile organic solvents from high-volume therapeutic compound syntheses, especially for regulatory filings in regulated markets.

    Industry compliance standards

    • Current Good Manufacturing Practice (cGMP) – ICH Q7
    • USP General Chapter <467> Residual Solvents
    • EU EudraLex Vol 4 for pharmaceutical solvents and process aids
    • FDA 21 CFR Part 211 Pharmaceutical production requirements

    Typical usage ratio

    • 15-40 vol% of total reaction mixture, tuned to ensure full substrate solubility and optimal conversion; amount reduced in multi-step processes via recycling

    Downstream process integration

    • Added at the initial substrate charging step in batch and flow reactors
    • Recovered through phase separation or distillation post-reaction step
    • Monitored for ionic impurities as part of quality assurance
    • Used in API synthesis, intermediate production, or process development batches

    Final product types

    • Pharmaceutical active ingredients
    • Complex organic intermediates and building blocks
    • High-purity specialty reagents
    • API precursor batches for regulatory submission

    5. Acidic Media for Solid Acid Catalysis in Dye and Pigment Manufacturing

    Dye and pigment producers utilize this ionic liquid as a medium for solid acid-catalyzed sulfonation and diazotization steps, particularly in the synthesis of azo and anthraquinone colorants. Its superior acid strength and low volatility allow precise temperature control and mitigation of hazardous vapor emissions, critical for occupational safety and environmental compliance. Formulators select concentration and contact time based on dye structure, desired particle morphology, and purity required for textile or ink applications.

    Industry compliance standards

    • ETAD (Ecological and Toxicological Association of Dyes and Pigments Manufacturers) Guidelines
    • REACH Registration for dye intermediates
    • ISO 9001:2015 Quality Management System
    • ZDHC (Zero Discharge of Hazardous Chemicals) requirements for textile auxiliaries

    Typical usage ratio

    • 5-12 wt% as a catalyst carrier per batch, optimized according to solid-liquid reaction system and target dye loading

    Downstream process integration

    • Dosed directly with main aromatic feedstocks at the catalytic reactor inlet
    • Recycled with aqueous washings after final product separation
    • Monitored for acidity maintenance and color yield parameters
    • Employment in small to intermediate scale specialty dye batch operations

    Final product types

    • Reactive and direct textile dyes
    • Inkjet printing pigments
    • High-stability food colorants (where approved)
    • Special effects colorant dispersions
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    Certification & Compliance
    More Introduction

    N-Methylimidazolium Hydrogen Sulfate: Advancing Modern Chemistry in Practical Terms

    What Drives Industry Interest in N-Methylimidazolium Hydrogen Sulfate?

    Behind each new chemical process stands the commitment to create better results for customers. We’ve spent years perfecting the production of N-Methylimidazolium Hydrogen Sulfate to ensure both performance and reliability, because these qualities matter every day on the plant floor. Teams across pharmaceuticals, biomass conversion, hydrocarbon processing, and specialty materials rely on this ionic liquid to handle the tough jobs that demand resilience and selectivity.

    Engineers and process chemists frequently ask what makes this compound different from conventional acids, solvents, or even other ionic liquids. The answer, from our experience running pilot plants and talking through customer processes, is that N-Methylimidazolium Hydrogen Sulfate outperforms legacy solvents by balancing acidity, thermal stability, and simple handling. Our production program includes models tuned to key purity values: 99% NMPHS, typical minimum, with trace water below 0.2%. By monitoring residual halides and metal content all the way through to packaging, our teams focus on what matters for downstream applications.

    How It Got Here: A Story of Real-Life Chemical Development

    During the early 2000s, customers supplied feedback on the limits of older hydrogen sulfate solutions. Equipment corrosion, lingering odor, poor recyclability—these got in the way. Synthesis methods needed adjustment. Our technical staff responded by refining local batch control, tweaking reactor geometry, and introducing improved in-line drying. Hands-on work with glass-lined reactors, rotary evaporators, and onsite analytical labs opened opportunities for greater product consistency. The drive to produce stable and transparent N-Methylimidazolium Hydrogen Sulfate came directly from these lessons.

    Today, demand no longer comes only from solvent replacement efforts. Researchers and lead engineers increasingly select this ionic liquid for high-acidity, low-volatility conditions, or processes where water content must be tightly regulated. The shift from random batch-to-batch variation to a narrow, reliable product profile allowed for wider adoption in electrochemistry, cellulose dissolution, and alkylation processes. Whether loading drums for export or scaling up internal R&D, our direct line between process innovation and day-to-day manufacturing ensures that improvements translate into full-scale supply.

    Specification Insights Rooted in Operations

    N-Methylimidazolium Hydrogen Sulfate carries the “model 1003” code in our contemporary product catalog. Production routines enforce minimum purity thresholds (≥99.0%), achieved by both distillation and fine-filtration. Our QC team checks for trace halides and metal contamination at every batch cutoff. Years of plant feedback taught us that even minor contaminants can slow reaction rates or introduce noise in sensitive syntheses—especially for scale-up in the pharmaceutical and polymer spaces.

    Most requests specify standard packaging in 25kg PE-lined drums, with 200kg containers staged for bulk users. Every drum leaves the plant labeled with batch date and moisture analysis to avoid surprises for customers calibrating their in-house balances. We found early on that even fractions of a percent in water content can impact viscosity and overall reactivity, so moisture control became core to our approach.

    Customers have asked about shelf life and transport resilience. Where some ionic liquids degrade after exposure to air or temperature swings, our experience says this variant keeps its integrity for over a year in sealed drums under ambient storage. Prioritizing non-corrosive seals, we moved away from metal closures to avoid product discoloration and off-odors. A focus on practical containment and cleanouts matters far more than technical gloss—maintenance and line-change crews benefit directly when components cooperate instead of introducing new layers of troubleshooting.

    Direct Applications and Real-World Problem Solving

    Industrial users continue to share challenges from routine plant runs. In the field, N-Methylimidazolium Hydrogen Sulfate often gets tapped for its capacity to serve as both an acid catalyst and as a green solvent in high-demand syntheses. In the cellulose conversion segment, technicians saw tangible boosts in yield during pretreatment and etherification steps. Research labs working at kilogram scale found that the product’s resistance to hydrolysis cut costs in work-up and allowed recycling protocols that saved both time and solvent overhead.

    For fine chemicals and alkylation projects, N-Methylimidazolium Hydrogen Sulfate let production teams run reactions with fewer acidic waste streams compared to mineral acids. We heard directly from customer maintenance leads who appreciate quieter pH profiles post-quenching and a lower secondary waste load than when using conventional handling acids. Iron and glass process lines hold up longer when the catalyst leaves less residue.

    Electrochemical device manufacturers reached out searching for a robust electrolyte with good ionic mobility and good solubilizing capacity for organic and inorganic compounds. Here, this ionic liquid checks those boxes without introducing the volatility and persistent odor problems tied to traditional solvents. Chronic leakage and exposure issues drop away—a difference that operators, not just managers, value during shift work. To support research, our team often fields technical support questions not just about product fit, but about vessel compatibility, mixing times, and cleaning procedures after batch runs.

    Key Differences Versus Other Acids and Solvents

    Questions about how N-Methylimidazolium Hydrogen Sulfate differs from other acids come up in nearly every customer visit. Unlike strong mineral acids such as sulfuric or hydrochloric, this ionic liquid has no corrosive vapor emissions. Field operators appreciate this—no whiff of acid in the air means a safer workspace and less corrosion risk for pumps and sensors.

    Volatility sets it apart from most traditional solvents. Teams running continuous extraction or closed-loop recycling systems notice far less solvent loss and a tighter process. Conventional sulfuric acid routinely needs vapor management, but our customers lowered air handling requirements when switching to this ionic liquid. The non-flammable nature shifts risk assessments and allows simpler insurance profiles—impactful to people managing risk and operational budgets.

    Thermal stability matters for folks running hot process steps: in reactors, autoclaves, and pilot plant loops, this material holds up at operational temperatures that would break down chlorinated or hydrocarbon solvents. Reprocessability—often overlooked up front—draws strong attention after thousands of cycles in a high-throughput production setting. Many plants have shared data showing that regeneration routines for this product outlive conventional organic acids without fouling or color change.

    In lab-scale applications, the key difference comes down to selectivity. N-Methylimidazolium Hydrogen Sulfate steers reaction profiles toward desired intermediates and reduces the formation of side-products, increasing the quality of the final yield. Analytical teams find downstream separation easier, and less time goes toward troubleshooting contamination or column clogging.

    Customers digging into lifecycle reviews highlight the reduced environmental toxicity and improved containment. Spill response shifts from urgent remediation to routine cleanup, and noxious byproducts don’t build up after disposal. This difference led some clients to overhaul their entire waste management regimes after switching.

    Meeting Industry Standards and the Trust Results Bring

    Years of feedback forged a practical appreciation for what partners actually care about: products show up meeting written specs, perform batch after batch, and don’t throw curveballs into maintenance, analytics, or waste handling. The in-plant teams keep logs on color, clarity, and smell—run-of-the-mill measures, maybe, but the kind that build repeat confidence every month. We built our runs around ISO-certified traceability, with full process logs available for each lot that leaves the filling line.

    Prior to shipment, our site’s onsite analytical lab tests for acid number, halide trace, color, and water. We pull random retention samples—no direct shipment without approval. This isn’t ceremonial box-checking. The times we caught moisture spikes, odd color, or batch separations, our logistics team flagged the issue and held inventory back rather than risk eroding a partner’s trust. Every problem solved upstream prevents downtime and claims in our partners’ plants—experience passed on in every delivered container.

    Staff in the filling hall and QA office stay connected through shared reporting, so if a process tweak needs review, it happens in real time. Plant techs value seeing that their observations on craft—such as new cleaning techniques or improved inert gas blanketing—mute the odds of batch deviation or recall. It’s this rooted, detail-oriented work that keeps a specialty chemical in circulation year after year, not marketing gloss or spec sheet claims.

    Supporting the Community: Training, Safety, Insight

    Over the decades, the specialty chemicals world has watched product knowledge pass along informally between technicians, site managers, and engineering teams. Newer field contacts push for documentation, guided walkthroughs, and clear lines of technical support. After dozens of site trials, we frequently send out video guides, host remote Q&As, and introduce new operators to proper transfer and recovery procedures. Most challenges surface not from the product itself but from how it’s introduced to existing process equipment.

    We include real-world safety lessons picked up on the ground: mixing protocols for batch charges, spill response tuned for viscous liquids, and guidance on how to flush lines prior to system startup. Trainers make plain which sections of the plant may see pressure increases or foam during thermal cycling. Experience walking the floor with new clients always turns up minor details—valve connections that fit, hose grades that last, and best ways to clock batch runs by color and tonality shift under load.

    New inquiries often surface from process development teams bringing plant-scale chemistry into new materials platforms or greener manufacturing methods. The broader transition toward lower volatility solvents and less hazardous catalysts drew in groups from electronics, bioplastics, and advanced coatings. Keeping up means feedback cycles stay short; our R&D and operations are tightly knit. When customers ask about new reaction conditions, or how to tune blends for longer campaigns, our formulation experts respond rapidly with trial samples and run logs rather than wading through layers of formal process.

    Operational Issues and Forward-Thinking Solutions

    Some challenges don’t show up until scale-up. A few clients noted carry-over of ionic residues after using N-Methylimidazolium Hydrogen Sulfate in multi-product vessels. We responded by sharing flushing protocols and, where necessary, introducing mobile polish filtration that catches trace hold-up between runs. Tight control on cross-batch contamination kept both yields and downstream safety where they needed to be.

    Disposal rules evolve as regulatory bodies monitor ionic liquids more closely. For years, close coordination with customer waste handlers and environmental service staff let us adapt disposal and recycling advice so that byproducts don’t sidestep compliance. In-house, plant staff sort and code waste streams early, keeping water-rich and product-rich residues separated. This makes downstream handling easier, prolongs the useful life of product, and keeps environmental penalties off the table for our clients.

    Transport brings its own set of hurdles—unpredictable temperature spikes, vibration, and slow customs clearances occasionally put strain on sensitive shipments. After early rounds of transit losses, we started running climate tracking and route planning alongside logistics companies, communicating container movement directly to customer staff. These lessons helped shrink delivery windows and reduced the odds of spoilage or off-batch shipments.

    Continuous Improvement by Listening to the Field

    We owe the quality of our N-Methylimidazolium Hydrogen Sulfate to hard-earned lessons from hands-on staff and the feedback loop between test labs, pilot lines, and industrial partners. The push for tighter specs didn’t come from internal targets but from honest reviews by synthesis chemists, maintenance leads, and process controllers who handle this product every month. Their real stories about better reactor uptime, cleaner process lines, and fewer incident reports inform every improvement our teams bring in.

    Process improvements continue year-round. Upgrades to batch tracing, sampling frequency, and in-line monitoring all came in response to shared operational findings, not wishful thinking. Even packaging modifications—from tamper-resistant seals to easier drum handling—emerge as practical answers to situations our shipment and warehouse staff have faced first-hand. This is the difference between a chemical made by the book and one shaped by years of actual plant use.

    We keep learning from our network—if a new regulation lands or a novel use case appears, the information flows both directions. Product reliability depends not just on a single innovation or marketing claim but on the trust and shared knowledge built with every delivery and every day in production.

    Looking Ahead: N-Methylimidazolium Hydrogen Sulfate’s Practical Role

    The global push toward greener chemical processing still sits somewhere in the middle. Customers expect materials like N-Methylimidazolium Hydrogen Sulfate to enable this shift without derailing plant operations or hiking costs. Investments in process improvement, transparent communication, and fast response to customer concerns keep efficiency and reliability within reach. Instead of chasing hypothetical advances, we focus on the details that matter on a factory shift: material that performs, shows up on time, and pulls through for engineers and operators.

    Over time, market signals shift. Industries entering advanced manufacturing or renewable feedstocks look for both legacy reliability and flexibility. Our teams meet these needs not by rebranding old solutions but by listening, adapting, and pulling from past on-plant experience. From fine chemicals to municipal-scale waste conversion, the compound’s go-anywhere, do-a-lot reputation relies on matching sound practices with credible, action-driven support.

    Staff from R&D, plant ops, and customer service stay close, ensuring changes in process or demand—be it purity requirements, alternative solvents, or new application chemistries—get real answers backed by data. The story of N-Methylimidazolium Hydrogen Sulfate is, ultimately, a shared one: shaped in the hands of the people who depend on it every day, spelled out by those who make sure it keeps working, and improved the honest way—from plant floor to process line and beyond.