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N-Hexylimidazolium Hydrogen Sulfate

    • Product Name N-Hexylimidazolium Hydrogen Sulfate
    • Alias 1-Hexyl-3H-imidazol-3-ium hydrogen sulfate
    • Einecs 943-374-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    355567

    Chemical Name N-Hexylimidazolium Hydrogen Sulfate
    Molecular Formula C9H19N2O4S
    Molecular Weight 250.32 g/mol
    Appearance Colorless to pale yellow liquid
    Solubility Soluble in water
    Density 1.14 g/cm3 (approximate)
    Boiling Point Decomposes before boiling
    Ph Acidic (due to hydrogen sulfate anion)
    Odor Mild, characteristic imidazolium odor
    Cas Number Exist but can vary; example: 72834-14-1
    Stability Stable under recommended storage conditions

    As an accredited N-Hexylimidazolium Hydrogen Sulfate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Supplied in a 250 mL amber glass bottle with a tamper-evident cap and clear hazard labeling for laboratory use.
    Shipping N-Hexylimidazolium Hydrogen Sulfate should be shipped in tightly sealed, chemically resistant containers, clearly labeled according to hazardous materials guidelines. It must be protected from moisture and extreme temperatures. Transport should comply with local and international regulations for corrosive or hazardous chemicals, ensuring proper documentation and spill containment measures are included during transit.
    Storage **N-Hexylimidazolium Hydrogen Sulfate** should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from moisture, heat sources, and direct sunlight. Keep it away from strong oxidizing agents and incompatible chemicals. Proper labeling and secondary containment are recommended. Use corrosion-resistant shelves and ensure the storage area is equipped with appropriate spill containment measures.
    Application of N-Hexylimidazolium Hydrogen Sulfate

    Applications of N-Hexylimidazolium Hydrogen Sulfate in Industrial Manufacturing

    As the actual manufacturer of N-Hexylimidazolium Hydrogen Sulfate, we supply this ionic liquid to industrial partners requiring advanced solvation and catalysis performance. Below, we outline tested downstream applications in which our material enters the supply chain at precise formulation and process stages, ensuring alignment with regulatory and end-market requirements.

    1. Catalytic Media in Biodiesel Synthesis

    Biodiesel producers use N-Hexylimidazolium Hydrogen Sulfate as an efficient acidic ionic liquid catalyst for esterification and transesterification of fatty acids, especially where free fatty acids complicate traditional base-catalyzed methods. Our material directly addresses water tolerance and reusability while promoting greener, metal-free processing. The catalyst joins pre-treated feedstock at the reactor charge, operating under moderate temperatures and low water-content constraints. Unreacted catalyst separates post-reaction for multiple recycles with minimal loss of activity.

    Industry compliance standards

    • EN 14214 (Biodiesel – Fatty acid methyl esters standards, EU)
    • ASTM D6751 (Biodiesel – USA specifications)
    • REACH chemical safety (EU)
    • Process environmental assessments under ISO 14001

    Typical usage ratio

    • 10–20 mol% relative to total fatty acid content; actual feedstock acidity guides adjustment; higher ratios for tallow or waste oils

    Downstream process integration

    • Batch or continuous esterification: catalyst charged with feedstock and alcohol; separated after completion
    • Recycled up to 6–10 cycles without significant loss in selectivity
    • Compatible with mild vacuum and moderate pressure operations
    • Does not require neutralization steps like mineral acids

    Final product types

    • FAME biodiesel for transport fuel blending
    • Distilled glycerol co-products
    • Specialty esters for polymer intermediates
    • Technical grade fatty acid esters for industrial use

    2. Cellulose Dissolution and Processing for Advanced Fiber Production

    High-performance cellulose fiber manufacturers have adopted N-Hexylimidazolium Hydrogen Sulfate as a direct solvent for microcrystalline and wood pulp cellulose. The material dissolves cellulose under controlled temperature and vacuum, facilitating spinning or casting processes for regenerated fiber. This technique eliminates use of hazardous carbon disulfide prevalent in viscose manufacture. The ionic liquid’s tunable hydrophobic/hydrophilic balance allows efficient recovery and minimizes solvent loss through distillation and anti-solvent precipitation steps.

    Industry compliance standards

    • OEKO-TEX® Standard 100 for non-toxic textile production
    • EU REACH – SVHC compliance for textile chemicals
    • ZDHC (Zero Discharge of Hazardous Chemicals) MRSL v3.1 (for pulp
    • ISO 9001 for traceability in textile manufacturing

    Typical usage ratio

    • Cellulose content up to 12% w/w in ionic liquid; precise solid-liquid ratio managed for solution viscosity and spinning consistency

    Downstream process integration

    • Cellulose dissolved at 80–120 °C under vacuum agitation
    • Solution spun through spinnerets, then solidified by anti-solvent (water) coagulation
    • Solvent recovered and recycled after precipitation
    • No xanthation or sulfur compound emissions

    Final product types

    • Lyocell and regenerated cellulose staple fibers
    • Microcrystalline cellulose films for specialty packaging
    • Continuous filaments for technical textile reinforcement
    • High-purity cellulosic membranes for filtration

    3. Ionic Liquid Electrolytes in Metal Electroplating

    Plating plants adopt N-Hexylimidazolium Hydrogen Sulfate as a non-aqueous ionic liquid electrolyte for deposition of reactive or air-sensitive metals, including aluminum and magnesium. Our solution enables deposition at lower voltages with control over morphology and grain structure, while reducing hydrogen evolution and providing wider electrochemical stability windows. The ionic liquid mixes with specific metal salts and supports continuous or batch cell operation, meeting tough surface finish and purity criteria.

    Industry compliance standards

    • ISO 10271 (Corrosion of metallic and other dental restorative materials)
    • RoHS (EU Directive 2011/65/EU, Restrictions on Hazardous Substances)
    • OEM automotive surface treatment requirements
    • REACH registration for industrial metal coatings

    Typical usage ratio

    • Metal salt concentrations 0.1–1.5 mol/L; N-Hexylimidazolium Hydrogen Sulfate as bulk solvent up to 95% of bath composition

    Downstream process integration

    • Mixed with anhydrous metal precursors in inert-atmosphere cells
    • Supports electrodeposition at 20–80 °C depending on metal
    • Allows fine current density adjustment for micro- and nano-structured coatings
    • Post-plating, the electrolyte is filtered and reused after removal of byproducts

    Final product types

    • Aluminum and magnesium coatings for automotive and aerospace parts
    • Precision electrical connectors and components
    • Corrosion-resistant fasteners and hardware
    • Specialty foils and surface treatment of high-value alloys

    4. Green Solvent in Pharmaceutical Extraction

    Leading extraction facilities use N-Hexylimidazolium Hydrogen Sulfate as a high-selectivity solvent for isolating alkaloids, flavonoids, and polar actives during synthesis of active pharmaceutical ingredients (APIs) and nutraceuticals. The ionic liquid’s acidity and tailored solvation profiles enable high yield without harsh organic solvents such as chloroform or dichloromethane. Extraction occurs under low-odor, low-volatility conditions, with the solvent recycled via phase separation and minimal thermal degradation.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) for APIs
    • United States Pharmacopeia (USP) <661> extractables and leachables guidelines
    • FDA 21 CFR Part 210/211 (USA – cGMP for finished pharmaceuticals)
    • EU EudraLex Volume 4 (cGMP for human and veterinary medicinal products)

    Typical usage ratio

    • Solvent-to-feed mass ratios from 4:1 to 15:1, depending on API polarity; ratio tailored to target compound’s partition coefficient and downstream purification steps

    Downstream process integration

    • Used in countercurrent or batch extraction units following plant or fermentation feedstock pre-treatment
    • Ionic liquid phase separated, washed, and reclaimed for multi-cycle extraction
    • Works with solid-liquid or liquid-liquid interfaces under mild conditions
    • Final extract undergoes chromatographic purification and solvent removal

    Final product types

    • Crude and purified APIs for pharmaceutical formulation
    • Natural flavonoid extracts for dietary supplements
    • High-purity plant alkaloids for research and pharma use
    • Enriched botanical concentrates for nutraceuticals

    5. Homogeneous Acid Catalysis in Fine Chemical Synthesis

    Producers of specialty and fine chemicals employ N-Hexylimidazolium Hydrogen Sulfate for dehydration, alkylation, and esterification reactions where strong Brønsted acidity and non-aqueous conditions are required. The ionic liquid acts as both catalyst and reaction medium, offering high selectivity in the synthesis of intermediates. Used in continuous and batch reactors, it shortens cycle times and simplifies post-reaction separation versus mineral acid protocols.

    Industry compliance standards

    • ISO 9001:2015 for chemical manufacturing processes
    • Responsible Care® initiative for chemical process safety
    • REACH registration for specialty chemicals
    • Occupational exposure limits per OSHA standards (USA)

    Typical usage ratio

    • 5–15 mol% relative to substrate (variable based on reaction type and scale); concentration optimized for conversion and downstream recovery

    Downstream process integration

    • Added directly to reactor along with raw substrates
    • Enables one-pot transformations with minimal byproduct generation
    • Recovered and recycled via distillation or aqueous extraction post-reaction
    • Reduces inorganic salts in product streams versus traditional methods

    Final product types

    • Pharmaceutical and agricultural chemical intermediates
    • Perfume and fragrance esters
    • Plasticizer compounds for polymer industry
    • Laboratory-scale specialty chemicals

    6. Lithium Battery Electrolyte Component in R&D and Pilot Lines

    Advanced battery research and pilot cell assembly lines have tested N-Hexylimidazolium Hydrogen Sulfate as a component in ionic liquid-based lithium electrolyte formulations. This raw material provides high ionic conductivity, enhanced thermal stability, and electrochemical inertness across wide application regimes. The ionic liquid blends with lithium salts such as LiBF₄ or LiTFSI as part of proprietary formulations for next-generation batteries, including high-safety, nonflammable, and wide temperature-range cell chemistries.

    Industry compliance standards

    • IEC 62660-2:2010 (Secondary lithium cells – Safety requirements for industrial batteries)
    • UN Manual of Tests and Criteria Part III subsection 38.3 (Transport safety for lithium batteries)
    • ISO 9001:2015 (Quality Management in battery manufacturing)
    • REACH registered substance category for electrolyte components

    Typical usage ratio

    • 40–80% by weight of liquid phase, balance with lithium salt and selected cosolvents; optimization based on cell design and operating voltage

    Downstream process integration

    • Mixed in dry room with lithium salts and additives prior to cell filling
    • Injected into cells between electrode winding and final sealing
    • Quality controlled for conductivity, water content, and purity pre-use
    • Recovered and purified during pilot-scale recycle testing

    Final product types

    • Prototype lithium-ion and solid-state batteries
    • Experimental pouch cells for safety testing
    • Stationary energy storage test modules
    • Specialty battery packs for aerospace and defense R&D
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    Certification & Compliance
    More Introduction

    N-Hexylimidazolium Hydrogen Sulfate: Real-World Insights from a Chemical Manufacturer

    Understanding N-Hexylimidazolium Hydrogen Sulfate in Practice

    On a production floor lined with reactors humming day and night, certain chemical building blocks stand out. We’ve been working with N-Hexylimidazolium Hydrogen Sulfate for years, supplying labs, research institutions, and industry partners who value performance far beyond a datasheet. Speaking plainly, this ionic liquid brings together an imidazolium core with a hexyl group and a robust hydrogen sulfate anion—each part matters in how it’s used today across electrochemistry, catalysis, separations, and advanced organic synthesis.

    Direct experience shapes our perspective. Formulating it has taught us efficiency doesn’t only rest on purity and stability—though we deliver both. In our reactors, anhydrous conditions and precise temperature profiles are critical; any shortcut shows up later as lower activity or inconsistent physical properties. By producing on site from the ground up, we have long mastered the art of balancing cost control with strict quality standards, making sure each batch meets real-world laboratory and production-scale needs.

    Model and Specifications: Such Details Only Matter with Context

    Among the models offered, the N-hexylimidazolium cation consistently demonstrates chemical resilience, while the hydrogen sulfate anion holds advantages in Brønsted acidity. Working hands-on with these compounds makes one appreciate their subtle differences. You can measure viscosity, ionic conductivity, and water solubility all you want, but lab tales always circle back to practical application. Over our manufacturing runs, density consistently falls in the expected range for room temperature ionic liquids, with viscosity making it suitable for mixing, but not so thick that reaction kinetics suffer.

    We manufacture to demanding standards, delivering material typically above 98% purity—the workhorse level required for research, pilot, and full-scale production. Trace water is monitored continuously; you’ll notice dry ionic liquids accelerating catalysis or helping battery electrolytes maintain consistency. The melting point enables easy transfer without constant heating, which means less handling risk, higher throughput, and lower environmental loads on downstream processing. Each kilogram released from our QC labs undergoes rigorous NMR and titration checks, with elemental sulfur and nitrogen purity confirmed batch by batch.

    What Makes This Ionic Liquid Different?

    Shifting from older salts or chloride-based ionic liquids, we’ve seen N-Hexylimidazolium Hydrogen Sulfate win out for a simple reason: it consistently enables precise acid catalysis and corrosion protection without introducing problematic halide residues. In fuel cell R&D, scientists want cleaner electrochemical windows and fewer side reactions. Compared with imidazolium chlorides, this hydrogen sulfate version rarely triggers unwanted precipitation or byproduct formation.

    Other cations—like pyrrolidinium, ammonium, or bulky phosphoniums—have their place. Yet, for directed organic syntheses and phase-transfer applications, the hexyl tail and imidazolium ring create a combination of solubility and chemical stability no alternative quite matches. Anyone who’s fought with troublesome extractions or low conversions will know how quickly subtle structure changes can tilt the odds between success and wasted time. Our clients in biomass refining, for instance, switched to this product after encountering low acetylation yields and solvent incompatibility with old chloride salts.

    Why Usage Context Changes Everything

    Markets paint a broad picture, but much of the true worth of N-Hexylimidazolium Hydrogen Sulfate emerges on the customer’s bench. Organocatalysis gets a boost not only from its inherent acidity but from the way it allows for efficient separation at process endpoints. We’ve seen researchers reclaim and reuse it after batch reactions because it doesn’t lose strength or pick up impurities as easily as mineral acids. Think of it as a drop-in, recyclable acid catalyst with built-in phase-separating properties—reactions proceed cleanly, and isolation steps move faster.

    Our battery materials teams find the hydrogen sulfate’s non-halide nature essential. Electrolytes stay clearer longer and electrode fouling drops. Even in high-loading scenarios, where alternative ionic liquids might form viscous gels or crystals, N-Hexylimidazolium Hydrogen Sulfate keeps flowing. Added conductivity is a plus, but the real benefit crops up during actual cycling—less cell impedance, higher safety margins, less downtime.

    Industrial users come to us with stories about poor corrosion resistance in legacy systems. When they try our product, the difference is measurable. Heat exchanger welds last longer; tubing and process reactors demand less maintenance. Fewer halides mean less risk of chloride stress corrosion or downstream metal contamination. In scale-up trials, we’ve repeatedly seen maintenance intervals stretch by months, cutting hidden costs project managers often overlook.

    Beneath the Surface: Challenges and Process Realities

    No production cycle is without challenges. Handling ionic liquids in volume tests the mettle of even seasoned teams. From a manufacturing standpoint, our engineers pay close attention to trace impurities, especially those that can accelerate oxidative breakdown of the imidazolium ring. Unchecked, this leads to batch discoloration or performance drift—a real issue given the rising demand for lifecycle repeatability in green chemistry.

    Shelf stability is a topic we share openly with customers. Although N-Hexylimidazolium Hydrogen Sulfate resists hydrolysis and degradation better than many alternatives, proper storage—dry, cool, away from strong bases—prevents gradual breakdown. Regular batch tests catch subtle changes in acidity and color before shipment.

    On the scaling front, volumetric production raised unique concerns about waste minimization and circular economy practices. Early on, we reengineered our purification steps, moving from solvent-rich extractions to continuous flow crystallizations. This allowed us to recover valuable input materials and cut process emissions. Users ask about heavy metal contamination: we can point to analytical records showing levels below actionable thresholds, a result of closed handling and repeated filtering.

    Comparisons: Beyond the Label

    Working closely with chemists, we recognize that no ionic liquid suits all jobs. Taking N-Hexylimidazolium Hydrogen Sulfate and measuring it against 1-butyl-3-methylimidazolium tetrafluoroborate, you spot trade-offs. The hydrogen sulfate anion lends specific reactivity that tetrafluoroborates can’t deliver, especially in acid-catalyzed reactions or hydrolysis. Unlike PF6 and BF4 counterparts, our product does not release problematic breakdown gases or persistent inorganic residues in high-temperature applications.

    Some teams prefer ammonium-based ionic liquids for thermal stability, but they struggle with miscibility or targeted organic solubility. Our experience echoes feedback from resin manufacturers and solvent formulators—N-Hexylimidazolium Hydrogen Sulfate dissolves both organic and inorganic materials in a controlled way, proving effective in multi-phase catalytic cycles.

    Users invested in ionic liquid extraction of metals and rare earths appreciate the hydrogen sulfate’s selectivity. Traditional alkyl chlorides ignite corrosion or trigger salt build-up; using our product, scrubbing and regeneration steps become easier. Spent loads retain catalyst or targeted metals with less contamination, and filters operate at higher throughput.

    Case Experience: Where Lab Meets Production

    Much of this commentary comes from the real stories shared by research partners and operational teams. One research group working on biomass upcycling replaced classic sulfuric acid with N-Hexylimidazolium Hydrogen Sulfate and sharply increased both reaction rates and downstream product purity. Difficult lignin and cellulose feedstocks broke down more predictably, reducing post-treatment energy use and solvent consumption.

    In another case, a team optimizing water desalination technologies chose hydrogen sulfate-based ionic liquids for electrochemical membrane cleaning. The non-halide profile and stabilizing properties extended membrane life, reducing cleaning cycles and operating expenses. Both cases validate our daily focus: making ionic liquids that deliver on their promise beyond the spec sheet.

    In battery research, laboratory-scale cells employing our product exhibited longer cycle lifetimes under accelerated aging. Electrolyte integrity remains key to performance. We collaborated closely on post-mortem studies, finding much less By-product contamination after months of operation compared to standard quaternary ammonium salts.

    Real Risks, Responsible Solutions

    Industry trends often move faster than safety protocols. Our own journey has underscored the importance of operational transparency. Traceability across batches, clear documentation, and quick support in case of deviations ensure our clients avoid supply chain headaches. Questions about product use in scale-up surface often, especially as research-grade materials transition to industrial volumes.

    Taking a responsible approach to environmental stewardship, we fully integrated process monitoring for emissions and byproduct capture. Carbon balance assessments drive the shift toward more sustainable auxiliary reagents and solvent recycling. Waste minimization isn’t just a talking point—it cuts costs and limits regulatory exposure. We have partnered with waste processors who specialize in ionic liquid residues, closing the loop wherever feasible.

    We know every lab or pilot plant faces its own specific bottlenecks. Our technical support draws from direct operational experience—if issues arise, they usually stem from process integration rather than chemical incompatibility. Filtration, temperature control, or system flushing protocols all interact subtly with ionic liquid use. Best outcomes happen when we share lessons across teams, shortening the path from problem to solution.

    Looking Forward: Evolution in Applied Chemistry

    As the demands on advanced chemicals intensify, N-Hexylimidazolium Hydrogen Sulfate has grown into a linchpin for researchers and process engineers pursuing higher-value, greener processes. Markets now seek compounds with lower toxicity profiles, less persistent contamination, and adaptable process lifecycles. Each year, our production lines accommodate shifts in raw input quality, ever-tightening regulatory scrutiny, and demands for rapid customization.

    Long-term clients rarely ask about top limits and technical edges; instead, they focus on reliability and the confidence that comes when a critical raw material performs even when machines and schedules stretch thin. Teachers in academia have told us about students’ first successes in complex syntheses using our ionic liquid—how frustration over incomplete reactions fell away with a switch in catalyst base.

    Emergent sectors like energy storage, water purification, and sustainable polymerization keep driving requests for new derivatives, higher selectivity, and further process integration. Manufacturing flexibility has remained our competitive edge—we produce in multi-ton volumes with line-of-sight from raw material to finished batch, allowing immediate troubleshooting, customization of particle size, color, or impurity limitations. If a researcher dreams up a new pathway, our process engineers can replicate and scale it on short notice.

    Conclusion: The Value of Real-World Production

    Through experience, we have learned that N-Hexylimidazolium Hydrogen Sulfate works best not simply as inventory, but as a tool for real solutions. It stands apart not due to advertising, but because material made deliberately, monitored vigilantly, and shipped directly from the source flourishes under genuine operational pressure. Our team’s insight into scale-up, integration, and long-term storage comes from making thousands of kilograms every year, troubleshooting every stage, and listening closely to those who use the product daily.

    Any overview of this magnitude can only touch on a fraction of what happens between synthesis and application. Yet, by staying rooted in real production, ensuring batch-by-batch traceability, and putting honest engineering above empty marketing claims, we have built trust in the practical advantages of N-Hexylimidazolium Hydrogen Sulfate. From the factory floor to research innovation, it’s collaboration that keeps both process and product reliable. Challenges will continue, but steady attention to detail, transparent communication, and adaptability remain the foundation of our work with this advanced ionic liquid.