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N-Ethylimidazolium Hydrogen Sulfate

    • Product Name N-Ethylimidazolium Hydrogen Sulfate
    • Alias NEIMHSO4
    • Einecs 634-850-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    900150

    Chemical Name N-Ethylimidazolium Hydrogen Sulfate
    Molecular Formula C5H10N2O4S
    Molecular Weight 194.21 g/mol
    Appearance colorless to pale yellow liquid
    Density 1.26 g/cm3 (approximate)
    Melting Point Below room temperature
    Boiling Point Decomposes before boiling
    Solubility In Water Miscible
    Ph Acidic (typically < 2)
    Cas Number 637040-52-5
    Application Ionic liquid, catalyst, solvent
    Odor Odorless or faintly amine-like
    Storage Conditions Store in a cool, dry place, tightly closed
    Refractive Index 1.48 (approximate)
    Hazard Classification Irritant

    As an accredited N-Ethylimidazolium Hydrogen Sulfate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g of N-Ethylimidazolium Hydrogen Sulfate is securely packaged in a sealed amber glass bottle with clear hazard labeling.
    Shipping N-Ethylimidazolium Hydrogen Sulfate should be shipped in tightly sealed, chemically-resistant containers, protected from moisture and incompatible substances. It must be clearly labeled and transported under ambient conditions with appropriate hazard documentation. Follow all relevant regulations for handling and shipping chemicals to ensure safe delivery and compliance with local and international guidelines.
    Storage N-Ethylimidazolium hydrogen sulfate should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from moisture and incompatible substances such as strong oxidizers and bases. Protect it from direct sunlight and sources of ignition. Proper labeling and secondary containment are recommended to prevent leaks and accidental exposure. Use appropriate personal protective equipment during handling.
    Application of N-Ethylimidazolium Hydrogen Sulfate

    Applications of N-Ethylimidazolium Hydrogen Sulfate in Industrial Manufacturing

    N-Ethylimidazolium hydrogen sulfate serves specific functions in several industrial sectors, offering ion exchange, catalysis, and solubilization capabilities to manufacturers with strict process and quality demands. As a chemical producer, we supply material that meets certifiable performance needs from pilot to bulk manufacturing scales.

    1. Cellulose Dissolution in Advanced Cellulose Materials

    In the advanced cellulose materials industry, our product acts as a task-specific ionic liquid to dissolve cellulose for fiber spinning, membrane casting, and composite fabrication. This eliminates reliance on volatile organic solvents and supports processes for high-value, regenerated cellulose derivatives. Manufacturers optimize dissolution temperatures and times to control degree of polymerization and final product properties. The ionic liquid must maintain stability under extended heating and shear during continuous batch production, balancing cellulose chain accessibility with minimal degradation.

    Industry compliance standards

    • ISO 9001-certified quality management systems for chemical production
    • REACH registration compliance for imported and exported chemical substances in the EU
    • OEKO-TEX® Standard 100 certification for cellulose-based fiber final products
    • National cellulose fiber regulations (e.g., Chinese GB/T, Japanese JIS standards)

    Typical usage ratio

    • Ranges 80–92% ionic liquid by mass to 8–20% cellulose, adjusted according to target viscosity and molecular weight distribution of the cellulose grade

    Downstream process integration

    • Directly used in the dissolution vessel as primary solvent prior to fiber spinning, casting, or shaping steps; recyclable via phase separation and regeneration after product precipitation

    Final product types

    • Lyocell fibers
    • Advanced composite membranes
    • Technical cellulose films
    • Functionalized nanocellulose dispersions

    2. Acidic Catalyst in Biodiesel Production

    In biodiesel production, this ionic liquid functions as a homogeneous acidic catalyst for transesterification and esterification of low-quality feedstocks with high free fatty acid content. Refineries employ it to achieve high conversion yields where traditional alkaline processes fail. The acid strength and thermal stability allow multi-batch use with minimal degradation, which lowers total catalyst consumption and enables easier downstream separation compared to mineral acids. Integration is subject to strict monitoring of water content and control of side reactions that could impact biodiesel purity.

    Industry compliance standards

    • ASTM D6751 specification for biodiesel (B100) blend stock
    • EN 14214 European standard for fatty acid methyl esters (FAME)
    • UN Globally Harmonized System (GHS) hazard communication for all process reactants and intermediates
    • ISO 14001 environmental management system guidelines for chemical processing

    Typical usage ratio

    • 3–10 mol% relative to total oil/fatty acid feedstock, precise dosing controlled by initial acid number and water content in the feed

    Downstream process integration

    • Added at the reactor charge stage and dispersed before the introduction of methanol or other alcohol reactants; recovered after separation and reused in subsequent cycles when feasible

    Final product types

    • Biodiesel fuel (FAME)
    • Distilled glycerin byproducts
    • Biodiesel blends for transportation applications

    3. Catalyst in Organic Synthesis for Pharmaceutical Intermediates

    Pharmaceutical intermediate manufacturers utilize this compound as a strong, non-volatile proton source and phase transfer catalyst in selected alkylation, acylation, and heterocycle formation reactions. The ionic liquid structure facilitates higher yield and selectivity, especially in syntheses sensitive to water or conventional acids. Operators adjust batch pH and temperature to maximize pathway efficiency and minimize unwanted byproducts. High purity requirements govern its introduction, emphasizing lot-to-lot quality consistency, and the ionic liquid can be efficiently extracted or degraded after the reaction for regulatory-compliant downstream processing.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice (GMP) for Active Pharmaceutical Ingredients
    • Ph. Eur 10.0 and USP specifications for pharmaceutical intermediates, depending on end market
    • 21 CFR Parts 210/211 FDA regulations for finished pharmaceutical products
    • Health and safety protocols from OSHA Hazard Communication Standard

    Typical usage ratio

    • 5–15 mol% of total limiting reagent in target reactions; fine-tuned based on substrate reactivity and final impurity profile targets

    Downstream process integration

    • Meticulously dosed into stirred batch reactors or flow reactors at the start of key condensation or ring closure reactions, with rigorous batch documentation for traceability

    Final product types

    • Alkyl- and aryl-substituted imidazole intermediates
    • Specialty active pharmaceutical substances pending further synthesis
    • Fine chemical building blocks

    4. Alternative Electrolyte Component in Electroplating and Metal Processing

    Electroplating facilities integrate this ionic liquid as a non-aqueous electrolyte or electrolyte additive for precise control over deposition quality and reduced hydrogen evolution with sensitive or complex alloy systems. The cationic structure prevents metal ion hydrolysis and enables smooth, crack-free deposit layers, particularly where traditional aqueous solutions suffer from impurities or pH instability. Application parameters such as temperature, bath composition, and current density are closely managed to leverage the physical and chemical properties of the ionic liquid over extended production runs.

    Industry compliance standards

    • ASTM B322 guidelines for cleaning metals prior to electroplating
    • ISO 9001:2015 certified quality systems for electrochemical manufacturing
    • European Chemicals Agency (ECHA) REACH regulation for electrolyte substances
    • ISO 14001 environmental management in surface treatment operations

    Typical usage ratio

    • 10–35 wt% of total electrolyte solution, optimized based on desired deposition rate, alloy composition, and thermal stability

    Downstream process integration

    • Added to the electrolyte tank during solution make-up and replenishment phases; monitored inline for degradation and metal ion loading throughout production cycles

    Final product types

    • Plated electronic contacts
    • Surface-hardened machine parts
    • Specialized corrosion-resistant coatings
    • Functional alloyed metal products

    5. Sulfonation Catalyst in Specialty Resin Manufacturing

    Producers of sulfonated specialty resins employ this material as an ionic liquid sulfonating agent, enabling more controlled and selective aromatic sulfonation processes versus conventional mineral acid catalysts. It allows efficient resin functionalization, improving temperature and mechanical stability in the final polymer network. Manufacturers carefully balance reactant ratios, process temperatures, and agitation profiles to maximize functional group introduction while minimizing cross-linking defects and unwanted byproduct formation. Stringent analytical methods verify consistent catalyst quality before use in polymerization kettles.

    Industry compliance standards

    • ISO 9001/14001 for quality and environmental management in polymer manufacture
    • EU REACH and CLP (Classification, Labeling and Packaging) Regulation
    • EN ISO 1043-1 for plastics identification and marking
    • Industry-specific technical data sheets for sulfonated resins

    Typical usage ratio

    • 2–12 mol% relative to aromatic monomer content, based on required sulfonation degree and resin application

    Downstream process integration

    • Introduced to the reactor during sulfonation step under inert atmospheres at specified process temperatures; separated from finished polymer upon wash and neutralization stages

    Final product types

    • Ion exchange resins for chemical processing
    • Fuel cell proton exchange membranes
    • Functional additives for coatings and adhesives
    • Water purification specialty medias
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    Certification & Compliance
    More Introduction

    N-Ethylimidazolium Hydrogen Sulfate: Perspectives from the Manufacturer

    Production Integrity Borne from Years of Practice

    Chemical manufacturing brings a set of challenges that never stay still for long. N-Ethylimidazolium hydrogen sulfate, a product developed and refined by our team, shows this with crystal clarity. Rather than chasing trendy formulations, we have spent years analyzing raw material sources, testing synthesis routes, and pushing toward reproducible quality. Each batch goes through a hands-on production process, combining N-ethylimidazole and sulfuric acid under controlled temperatures and constant technician supervision. Quality comes from experience–the goal is not just purity, but dependable function. Over successive production cycles, our chemists document every minor shift in color, yield, and stability, learning to recognize the patterns that signal real-world reliability.

    Experience has taught us the temperamental nature of organic salts like N-ethylimidazolium hydrogen sulfate. Minor fluctuations in feedstock purity or environmental humidity can wreak havoc on reproducibility. Our facility handles this by maintaining tight control over all raw material lots and insisting on regular in-process checks. These efforts support consistent physicochemical properties: our current material presents as a pale, almost pearly solid, showing minimal clumping and ready-flowing granules. Getting to this stage cost years of careful tweaks to reaction timings and post-processing steps, especially during filtration and drying. In contrast, we have encountered trader-supplied product whose texture shifts from sticky powder to dense block depending on shipment: the difference comes down to production discipline, not luck.

    Understanding Specifications through Real-World Handling

    Across end-user industries, small details separate routine chemicals from trusted building blocks. Our N-ethylimidazolium hydrogen sulfate avoids the catch-all category of “ionic liquids” seen in catalogs because we learned early that properties like conductivity and solubility change sharply between batches that look identical on a lab bench. Industrial clients approach us with requests, asking not just for “purity” but confirmation of trace water content and absence of volatile amines. Instead of outsourcing, we run Karl Fischer titrations and gas chromatography in-house, to prove the moisture content and headspace remain within operational limits appropriate for catalytic and energy storage uses.

    Each production run averages near 99% chemical purity by HPLC and titration—though we pour time into verifying residual acidity, since even a hint of unreacted sulfuric acid will degrade polymer membranes or sensitive catalysts. The slightly acidic odor reveals usable concentration, rather than trace contaminants. Particle size sticks in the narrow range between sand and table salt—coarse enough for weighed transfer, fine enough to dissolve fast in organic media. Experience tells us that tight screening gives smoother downstream processing. It is not about chasing theoretical “ultra-high-purity” targets or advertising tempting numbers; what matters is practical consistency batch-by-batch, supporting real chemistry rather than just satisfying procurement checklists. Our operations staff takes pride in handing over material stamped as “fit for process trials,” not simply boxed and shipped.

    Applications Built from Industry Collaboration

    N-ethylimidazolium hydrogen sulfate does not live in a vacuum; the applications shape its manufacturing priorities. The first serious adoption arose from clients working on organic transformations, particularly acid-catalyzed reactions. They told us directly: conventional Brønsted acids fail to provide both the sustained reaction kinetics and the solvent compatibility needed for new-generation alkylation and esterification lines. The ionic liquid form of our product dissolves easily with many organic partners and brings manageable, predictable acidity–no runaway exotherms, no fouling of glassware. Reproducibility stands at the heart of its value, as lab trials must translate to pilot batches without unexplained rate drops or byproduct formation.

    Later conversations with researchers and engineers led to uptake in electrochemical cells. The straightforward composition, absence of halides, and mid-range ionic conductivity allow for direct introduction into prototype batteries and supercapacitor electrolytes. Several groups have experimented with our batches in non-aqueous conditions and noted stable electrochemical windows that support both redox flow and low-voltage organic transformations. Maintaining this performance means genuine attention to trace metal residues: our plant employs dedicated glass-lined reactors and monitors for leaching, aware that even spare parts contamination undermines end-use stability. We did not arrive at these conclusions by copying textbook recipes but by facilitating dozens of user-site troubleshooting sessions, often dispatching samples with micro-scale process adjustments to meet changing industry standards.

    How Handling Dictates Usability

    Manufacturers must think about more than molecule assembly—they face hands-on questions of storage, transfer, and downstream integration. From the outset, our engineers recognized that N-ethylimidazolium hydrogen sulfate’s hygroscopicity posed both risk and opportunity. The product pulls moisture from the air over days, raising the chance of surface caking or off-odors if packaging slips below par. We rejected low-cost bag seals used by traders and shifted to vacuum-sealed double-liner kegs, which needed custom handling protocols. The reward comes in product that spends weeks in satellite warehouses without transforming texture or inviting unplanned reactions. End users notice the difference at unpacking: the pellets stay free-flowing, without the sticky residue that signals cross-contamination or substandard packaging.

    Our facility also prioritizes traceability. Instead of labeling per shipment, we apply batch-specific tracking from synthesis through packaging—a discipline refined through cooperation with regulatory and pharmaceutical partners. Unexpected deviations, such as spot discoloration or odor, become rare because every jar traces back to its mother batch and process notes. When users share feedback—good or bad—we can rapidly link results to specific lots, protocols, and even weather records. Such traceability escapes many chemical suppliers, especially those reliant on reselling or contract manufacturing, but makes a world of difference to process engineers who need unbroken documentation during build-out or troubleshooting.

    Comparison with Other Ionic Liquid Products

    Many buyers ask about the difference between N-ethylimidazolium hydrogen sulfate and the better-known [BMIM][HSO4] or [EMIM][HSO4] salts. Years in chemical manufacturing have taught us that substituent structure affects not just melting point or price, but true process outcome. BMIM-based salts often arrive as high-purity clear liquids, but their viscosity under warehouse conditions turns pouring into a struggle, especially for automated feeders. Imidazolium variants bearing longer or bulkier alkyl chains impose their own blending hurdles—one section of customers favors our N-Ethyl version because it balances manageable melting temperature with rapid dissolution in both polar organic and water-miscible systems.

    Volatility also guides product selection. N-ethylimidazolium hydrogen sulfate’s lower volatility than short-chain alternatives means occupational exposure remains low during transfer and storage. Some operations opt for methyl or butyl-imidazolium analogues only to discover their reactors pick up unexpected loss due to evaporation, especially under continuous vacuum operations. By offering the N-ethyl variant, we help clients minimize open-system handling losses, reducing both environmental and worker safety concerns. Practicality wins out over catalog abundance.

    Applications tell another story: clients working on ionic liquid catalysis complain that “one size fits all” rarely delivers. Our process development partners confirm that acidity, hydrogen bonding, and even halide content (or their absence) shape catalyst leaching rates, product yield, and material compatibility. N-ethylimidazolium hydrogen sulfate won out in several direct comparisons for its moderate acidity—strong enough to push reactions but gentle enough to protect sensitive organic intermediates or membrane materials. In electrochemical work, the absence of halide ions (found in some other imidazolium salts) prevents electrode fouling and extends test cell lifespan. Comparisons only matter when measured at application scale, and our findings come straight from regular site trials, not just from chemical theory or marketing claims.

    Commitment to Safer, Sustainable Practices

    Sustainability has grown from buzzword to operational cornerstone in chemical manufacturing. Over years of plant upgrades, we have revised synthesis protocols for N-ethylimidazolium hydrogen sulfate to minimize both solvent use and waste generation. Traditional methods relied on open-batch acid neutralization, which posed hazards of fume emission and spill. Our current continuous flow setup reduces open air contact, captures volatile byproducts, and enables careful titration to endpoint—leading to both a safer plant floor and cleaner product.

    We pursued closed-loop reclamation for mother liquors and off-spec batches, refining routes to separate and recycle excess sulfuric acid and N-ethylimidazole. Chemical engineers review data from each shift, looking for evidence of yield drift or unnecessary side reaction, with a clear eye toward reducing energy and water consumption over time. We see this not just as regulatory defense but as a driver of operational savings and community safety. Gradually, packaging shifted from multi-material drums to mono-material containers, offering both lighter transport weight and higher recycling value at downstream facilities. None of these changes came overnight, and each step involved working closely with line operators, who spot the subtle process faults before they spiral.

    Partnerships that Drive Innovation

    We could not have developed or maintained N-ethylimidazolium hydrogen sulfate’s standing without deep user feedback. Several long-term customers, spanning fine chemicals and materials research, push our team with requests ranging from ultra-low-metal variants to specially milled grades for microreactors. Our technical staff work alongside formulation chemists at these firms; sometimes we receive data on reaction rate, foam behavior, or unexpected degradation, and head back to the lab for root-cause analysis. Collaboration of this nature helps us see our product through the lens of those who rely on it for breakthrough results, rather than treating it as a commodity. We adapted our drying and packaging protocols specifically to meet feedback from pharmaceutical clients, who needed scientific documentation for every parameter and trace impurity. Compared to distributors who hand off samples without contextual expertise, our entire ethos centers on solving user challenges as they arise, in real-world scenarios, not just laboratory glass.

    Academic groups seeking innovative ionic liquids have brought their own array of needs. As specialized catalysis or energy storage technologies evolve, the value in making rapid adjustments on production conditions–from reaction time to crystal habit–comes to the fore. Our pilot plant offers the flexibility to adjust specific properties per collaboration: a batch with modified pH or tailored particle size, or one destined for isotopic labeling to support mechanistic studies. Mutual learning benefits both sides; we incorporate academic process improvements, and they gain access to stable, non-commercialized production lots that support longer-term viability studies.

    Ongoing Evolution in Specifications and Demand

    Product development rarely moves along a single, predictable trajectory. We have seen N-ethylimidazolium hydrogen sulfate undergo shifts in usage profile within a decade—driven by regulatory pressure on volatile acids, new green chemistry frameworks, and changing end-user engineering. Material that once found its main outlet in chemical synthesis now enters markets involving electrochemical applications, materials science, even low-temperature lubrication. Each new pathway brings fresh expectations: one sector prioritizes purity and water content, another targets ease of packaging, and another seeks documentation suitable for export compliance. Our technical files now outnumber data sheets by an order of magnitude, cataloging every adjustment and test.

    The regulatory climate shapes handling, too. European and Asian standards for trace byproducts and hazardous shipping require that we run supplementary tests and offer certifications beyond what most traders even attempt. This means sending staff to seminars and investing in laboratory upgrades every budget cycle—a necessity for long-term viability. Customer audits push us to refine both paperwork and daily procedures, sometimes uncovering overlooked risks or opportunities for process tightening. We learned to anticipate regulatory shifts, so our clients experience no last-minute compliance emergencies or awkward border delays, preserving operational trust.

    Why Experience Counts in Industrial Chemistry

    Chemical manufacturing thrives where practical experience meets honest accountability. N-ethylimidazolium hydrogen sulfate exemplifies this: each lot shipped represents thousands of hours spent not just on reaction chemistry, but on understanding how minor process variables impact outcomes downstream. Regular dialog with users surfaces quirks and edge-cases never seen in textbook recipes. A change in solvent grade, a switch in storage temperature, or a tweak to mixing speed each spark new learning, prompting small, targeted improvements over time.

    We carry this approach to every customer relationship. Large or small, users care about whether the material works reliably, whether the paperwork lets them pass audits, whether they save time at every transfer step, or whether they reduce supply chain headaches. Those answers rest not just in a fixed specification, but in manufacturing that adapts and anticipates shifting priorities. Our job is to bring chemical realities together with evolving industrial needs, keeping N-ethylimidazolium hydrogen sulfate a dependable tool in every user’s toolkit. It is not about being first to market or offering the lowest sticker price, but about standing behind materials when they matter most.