Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

N-Acetylanthranilic Acid

    • Product Name N-Acetylanthranilic Acid
    • Alias 2-Acetamidobenzoic acid
    • Einecs 209-504-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    442101

    Iupac Name 2-acetamidobenzoic acid
    Cas Number 89-52-1
    Molecular Formula C9H9NO3
    Molar Mass 179.17 g/mol
    Appearance White to off-white crystalline powder
    Melting Point 198-200 °C
    Solubility In Water Slightly soluble
    Density 1.38 g/cm³
    Pubchem Cid 7338
    Smiles CC(=O)NC1=CC=CC=C1C(=O)O
    Inchi InChI=1S/C9H9NO3/c1-6(11)10-8-5-3-2-4-7(8)9(12)13/h2-5H,1H3,(H,10,11)(H,12,13)
    Un Number UN 2811
    Synonyms Acetylanthranilic acid, 2-Acetylaminobenzoic acid

    As an accredited N-Acetylanthranilic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The 100g N-Acetylanthranilic Acid is packaged in a tightly sealed amber glass bottle with a printed hazard and identification label.
    Shipping N-Acetylanthranilic Acid should be shipped in tightly sealed containers, protected from light, moisture, and incompatible substances. It is typically handled as a non-hazardous organic chemical, but standard laboratory safety and environmental precautions must be followed. Ensure appropriate labelling and documentation, and comply with local, national, and international shipping regulations.
    Storage N-Acetylanthranilic Acid should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from direct sunlight, moisture, and incompatible substances such as strong oxidizing agents. The storage area should be clearly labeled and equipped to prevent unauthorized access. Safe handling procedures and appropriate personal protective equipment should be used when handling the chemical.
    Application of N-Acetylanthranilic Acid

    Applications of N-Acetylanthranilic Acid in Industrial Manufacturing

    N-Acetylanthranilic Acid serves as a critical intermediate in several specialized downstream manufacturing sectors. Our direct production and in-house quality oversight ensure tight control over purity and performance, meeting the rigorous demands of these technical fields. The application areas listed below focus exclusively on established, real-world industrial uses, reflecting our decades of supply experience and technical collaboration with manufacturing partners worldwide.

    1. Pharmaceutical Intermediate for Antipyretic/Analgesic APIs

    Pharmaceutical producers primarily use N-Acetylanthranilic Acid as a key building block in the multistep synthesis of non-opioid central analgesics, including certain quinazolinone derivatives and active pharmaceutical ingredients (APIs) such as mefenamic acid. Integration occurs early in the API pathway, relying on precision reaction steps and strict process controls. Formulators incorporate the intermediate in regulated synthesis trains, ensuring traceability and final batch consistency for subsequent compliance with global pharmacopeial specifications upon scale-up.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • United States Pharmacopeia – General Chapter <823>, relevant monographs for APIs
    • EU GMP Part II (ICH Q7) and EudraLex Volume 4
    • Chinese Pharmacopoeia (latest edition) for API imports/exports

    Typical usage ratio

    • Varies from 0.9 to 1.3 molar equivalents per target molecule, adjusted depending on reaction yield, catalyst efficiency, and downstream impurity profile requirements

    Downstream process integration

    • Added during the initial synthetic step for amide bond formation; often used in batch or semi-continuous reactors under controlled temperature and inert atmosphere, followed by purification and transfer to the next synthesis stage

    Final product types

    • Bulk APIs (e.g., mefenamic acid)
    • Finished dosage forms (tablets, capsules)
    • Prescription and OTC pain relief medications

    2. Dye and Pigment Intermediate in Azo and Anthraquinone Systems

    N-Acetylanthranilic Acid plays a crucial role in the formulation of intermediate compounds for the manufacture of high-performance azo dyes and selected anthraquinone pigments. Producers use it during the early construction of dye molecules, ensuring chromophore stability and precise batch-to-batch hue reproduction. Its addition improves yield during coupling reactions on aromatic amines and assists in achieving consistent color strength and dispersion properties for demanding textile and industrial applications.

    Industry compliance standards

    • GMP for Colorants (ETAD guidelines)
    • REACH Registration (EU 1907/2006) – Safety Data and SVHC compliance
    • OEKO-TEX® Standard 100 Annex 4 – Restricted Amines & Dyes
    • ISO 9001:2015 for colorant manufacturing process control

    Typical usage ratio

    • Addition of 5–15% by mass relative to the amine component, optimized per target dye chromophore structure and desired purity

    Downstream process integration

    • Incorporated in aromatic condensation or coupling stages; controls introduced at pH-sensitive reaction vessels, often prior to diazotization or cyclization depending on the pigment or dye route

    Final product types

    • Reactive and disperse textile dyes
    • Anthraquinone-based pigments for coatings
    • Printing ink intermediates

    3. Fragrance & Flavors Ingredient—Aromatic Ester Manufacturing

    Specialty chemical producers deploy N-Acetylanthranilic Acid as a precursor for the synthesis of aromatic esters used in perfumery and flavoring. Through controlled esterification and further molecular refinement, it gives rise to components characterized by intense grape or cherry notes. The precise incorporation ensures regulatory conformity for food-contact and personal care applications, where trace residue limitations and organoleptic purity require consistent, verifiable sourcing.

    Industry compliance standards

    • IFRA (International Fragrance Association) Code of Practice
    • FDA 21 CFR 172.515 – Synthetic Flavoring Substances
    • Food Chemicals Codex (FCC)
    • European Regulation (EC) No 1334/2008 on flavorings and food ingredients

    Typical usage ratio

    • Reactant dose normally at a 1:1 molar ratio for complete conversion to the target ester, with final flavor/fragrance preparation levels ranging from 0.05–1.0% by weight in concentrates

    Downstream process integration

    • Subjected to acid-catalyzed esterification in closed reactors followed by distillation and refinement; performed under GMP-like controls for supply into flavor or fragrance compounding lines

    Final product types

    • Industrial grape and cherry flavorings
    • Cosmetic-grade fragrance base notes for perfumery
    • Food-grade flavor concentrates for beverages and confectionery

    4. Agrochemical Intermediate—Auxin Plant Growth Regulator Synthesis

    N-Acetylanthranilic Acid functions as a strategic intermediate in the synthesis of certain auxin-based plant growth regulators. As one of the feedstock molecules, it advances conversion routes to bioactive compounds that promote root development and regulate growth cycles in commercial agriculture. Downstream users employ this intermediate for its reactivity and purity, facilitating precise formulation of high-value, crop-specific regulatory agents subject to regional pesticide and plant health directives.

    Industry compliance standards

    • FAO/WHO Specifications for Plant Protection Products
    • EPA (U.S.) Regulation 40 CFR Part 180—Tolerances and Exemptions for Pesticide Chemicals
    • European Union Regulation (EC) No 1107/2009 (Plant Protection Products)
    • ISO 9001:2015 for agrochemical manufacture batch control

    Typical usage ratio

    • Utilized at 0.8–1.2 molar equivalents in synthesis of target active substances; downstream formulations adjust actives concentration typically to 0.1–0.5% in market-ready agrochemical products

    Downstream process integration

    • Introduced during the condensation and derivatization step in multi-stage batch synthesis; typically performed in cGMP-compliant closed systems to prevent cross-contamination

    Final product types

    • Auxin-based plant growth regulators
    • Rooting stimulants (liquid and powder forms)
    • Specialty foliar spray solutions
    Free Quote

    Competitive N-Acetylanthranilic Acid prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    N-Acetylanthranilic Acid: Trusted Production from the Source

    Introducing Our N-Acetylanthranilic Acid

    Manufacturing chemicals is more than just a business—it’s a science that demands respect for precision, reliability, and safety. Our N-Acetylanthranilic Acid starts its journey from carefully sourced raw materials and undergoes a process where every critical variable gets constant attention. As a manufacturer, we consider this an essential intermediate for many downstream applications. We have seen the demand for high-purity intermediates rise, especially as the pharmaceutical and specialty chemical sectors continue to push their expectations for both performance and purity.

    Our N-Acetylanthranilic Acid comes in technical and refined grades. Consistency matters. In our production lines, purity typically reaches 99% or higher as measured by HPLC, and we confirm each batch against internal reference standards. Form and appearance stay intentionally predictable—this provides flow in handling and storage, reducing clumping and bridging when introduced into blending or synthesis. We pay attention to measurable characteristics: color (white to off-white crystalline powder), melting range (usually between 183°C and 186°C), and low moisture content, all verified by hands-on inspection and modern analytical tools.

    Why Our Approach to Manufacturing Matters

    Real chemistry happens on the shop floor, not just in the datasheet. Our entire operation—from reactor design to purification and packing—has evolved through decades of continuous use and troubleshooting. Early in the process, we realized that temperature swings in acetylation led to variable product profile, so we implemented automated temperature and pH controls to hold the reaction window tight. Product that falls short goes back for rework—a practice enforced by our seasoned production supervisors who know the material inside and out.

    Handling intermediates like N-Acetylanthranilic Acid daily, we’ve learned the importance of batch-to-batch stability. Changes in raw materials or conditions can echo all the way downstream, affecting final yields and quality in your applications. Regular, in-house testing with validated methods is our norm. Every lot moves only after passing a battery of tests—melting point, impurities, residual solvents—with results logged and rechecked along the way. Our experienced staff tracks trends, identifying any drift long before it affects your supply.

    Where It’s Used—and Why Fit Matters

    Over the years, N-Acetylanthranilic Acid carved out its place as a valuable intermediate in pharmaceuticals, dyes, flavors, and research. It’s particularly recognized as a precursor for anti-inflammatory and antihistamine drugs, relying on a dependable source of untainted material with known impurity profiles. The importance extends beyond purity. In fine chemical synthesis, unexpected minor impurities can complicate downstream processing. With us, you get a product that has survived real-world scale-up and meets the thresholds demanded by specialists who cannot afford mistakes in their input stock.

    Pharmaceutical manufacturers and contract research organizations depend on uninterrupted, predictable supply. As the original producer, we provide batch reservation and long-term planning, since we know how much logistical delays or shifting material specs can disrupt pilot runs and full commercial launches. Our material withstands high-temperature processing and maintains its structure even during prolonged storage, resisting hydrolysis and color change when kept under recommended conditions. We have seen labs shave valuable time from purification steps simply by starting from our N-Acetylanthranilic Acid instead of less consistent alternatives.

    Moving Beyond Commodity—How Our Product Stands Apart

    Not all N-Acetylanthranilic Acid comes from a manufacturing line that puts quality first. Many products in the marketplace originate from trading companies or toll producers without core process knowledge. They may supply something that passes a superficial assay, but hidden byproducts or broad melting ranges can crop up and cause bottlenecks in sensitive downstream workflows.

    Typical off-the-shelf material often arrives with higher levels of orthanilic or meta-isomers, and batch records can be vague or missing. In our facility, from the incoming aniline derivative to the finished sealed drum, we hold raw data, full process traceability, and real accountability for every kilo we produce. This dedication translates to lower lot-to-lot variance and a clear path for troubleshooting if a customer requests additional data. Through these practices, we’ve built trust directly with formulation chemists and procurement teams seeking a reliable, single-source manufacturer.

    Low-volume specialty chemical manufacturing differs vastly from commoditized bulk runs. To maintain risk controls, we set aside finished inventory for repeat buyers and place standby staff on alert during customer production campaigns. We keep on-site reserves of reference standards for NMR and IR characterization, helping our partners quickly resolve any technical question about the material. Direct dialogue between our plant chemists and customer development teams closes the feedback loop, allowing both sides to pre-empt possible production issues before they escalate.

    Model, Performance, and Real-World Experience

    Our principal offering, labeled as model NA-731, sits in the 99%+ purity class and ships globally to regulated markets. Each drum or bag comes with a comprehensive certificate built by our own analytical team. Some users prefer micronized forms—especially for certain solid-phase syntheses or when seeking better dispersion. On request, we provide custom particle size distributions, and we modify the filtration process to deliver tighter or broader cutpoints based on your feedback and observed application needs.

    Years ago, a surge in demand exposed weaknesses in supply chain resilience. We responded by doubling reactor capacity and qualifying backup filtration equipment, ensuring stable output even during power fluctuations or supply interruptions for acetylating agents. By keeping control over equipment selection, staff training, and raw feedstock hedging, we avoid the last-minute substitutions that can bring unplanned structural impurities into the material. This is how we shield our downstream users from recall risks or batch losses that arise from inconsistent input quality.

    Different manufacturers set their own internal standards. Our threshold for allowable single impurities stays tighter than typical industry norms. This reflects real experience—chemists in process development rely on us to help them sidestep side reactions and purification headaches. When we supply a kilo, it comes from a batch with a full chain-of-custody. Our regular customers know that they receive authentic, in-house produced material, not repackaged stock from undisclosed origins.

    Critical Differences from Other Sources

    Efficiency and predictability often take a hit when users try lower-priced alternatives. Our partners have shared stories of missed project deadlines due to off-odor samples, overstated assays, or undocumented residual solvents from other suppliers. When N-Acetylanthranilic Acid comes straight from the manufacturer, chemistry teams gain transparency over each step from synthesis to drumming. We support customer audit visits and walk-throughs—rare in the field, but a standard part of our open-door culture.

    Contamination prevention is another area where experience matters. In our production environment, lines handling N-Acetylanthranilic Acid remain segregated from incompatible chemicals, using color-coded tools and dedicated vessels. Regular audits and in-house cleaning validation make sure we avoid carryover, which is a leading cause of unexplained reactivity or yield loss in user plants. End users scale up their operations with greater confidence, knowing that reproducibility starts at the very beginning of the material’s life.

    Post-shipment support cannot be an afterthought. Users value direct access to someone who can answer technical questions with context—not just shipping departments or third-party sales. Our technical and operations teams handle incoming issues, so buyers deal directly with the people who produced and tested their material. The knowledge base here includes all typical production variables, batch adjustments, and even seasonal effects on product behavior. We know how N-Acetylanthranilic Acid behaves during long sea voyages, prolonged storage, or under variable humidity. As a result, we give honest recommendations to end users, making sure application-specific requirements drive each shipment.

    The Role of Traceability in Today’s Market

    Traceability has become a defining factor in chemical procurement. As regulatory scrutiny grows—especially in pharma and international trade—being able to link every batch of N-Acetylanthranilic Acid to full, real-time production data proves vital. Each package comes with a certificate that reflects the week’s analytical signature, and we retain samples and production files for years beyond shipment. We invite audits and have responded to numerous customer and regulatory inspections, always providing full transparency.

    This level of record-keeping isn’t industry standard. In our facility, every production lot appears in a digital logbook cross-referenced with the intake, synthesis, isolation, and packing parameters. When issues arise at any stage, we access details immediately—down to specific oven loads or the operator responsible for every process. Gaps, which sometimes plague loosely controlled sites or contract processors, never creep into our reporting. This empowers our partners to respond confidently to compliance requests or end-user audits without scrambling for paperwork or backtracking through intermediaries.

    Meeting the Future of Quality and Supply

    The global landscape keeps raising the bar. Drug manufacturers and specialty chemical firms need material that not only fits strict impurity thresholds but also arrives on time and performs predictably. Because we have lived through market cycles, raw material interruptions, and evolving regulatory landscapes, we recognize the value of securing both process consistency and responsive logistics infrastructure. Our investment in process automation and robust staff training shields customers from uncertainty.

    Research institutions rely on us for small lots fit for pilot studies and preclinical work. Once their projects move toward scale-up, we guarantee scalable supply without jumping to another toller or third-party supplier. We have made capability upgrades and maintain supply agreements that take project ramp-ups into account. Our strong relationships with shipping providers ensure that delivery timeframes stay realistic and transparent, even during port slowdowns or unexpected customs questions.

    We see real value in cross-team dialogue. Customer technical staff often run into workflow bottlenecks or novel application requirements as they innovate. Open lines to our chemists and engineers mean tailored solutions—a custom filter grade, a dried form with extra-low water, or adjusted packing for remote installations. These exchanges keep both sides at the frontier of application performance and process safety.

    Responsible Manufacturing and the Bigger Picture

    Making N-Acetylanthranilic Acid right impacts more than the bottom line; it affects safety, project continuity, and environmental stewardship. Chemical emergencies or uncontrolled releases can ripple downstream. We take process safety seriously, with preventive maintenance and environmental controls built into our equipment. Regular training keeps frontline operators aware of both process chemistry and safe handling. Proper attention to emissions, waste handling, and water management also ensures long-term sustainability.

    Sustainability doesn’t sit apart from quality. Our waste minimization runs parallel with yield optimization—reclaiming solvents, improving reaction selectivity, and reducing process water. Customers gain from these improvements as well, benefiting from consistent supply and a smaller carbon footprint attached to every shipment. Industry certifications are not marketing tools for us but reflect ongoing, methodical adherence to updated standards. External audits confirm our operations, but sustained relationships with partners show the real measure of our output.

    What It Means to Buy Direct from Us

    Chemical buyers pick their sources for a reason. Those who choose a direct line with our plant access more than just a specification—they enter a relationship shaped by accountability and practice. Experience tells us that switching sources can mean hours of lab retesting, process revalidation, and unexpected issues with yield or side products. Our regular buyers report fewer deviations and enjoy smoother audits with upstream data at their fingertips.

    Orders placed through our direct channels run on true production lead times, not secondary warehouse drawdowns. Packaging reflects customer needs—large-run manufacturers take sealed fiber drums or lined boxes, while laboratory-scale or early-stage projects often start from double-sealed vials or jars packed in climate-controlled conditions. Shipments stay protected during transit, and every container carries traceable lot numbers for easy recall and compliance checks.

    The benefits flow through every department. Procurement staff gain peace of mind knowing the original source of the material; lab QC analysts handle samples with full access to batch details; process chemists see fewer troubleshooting incidents and reduced losses in their own synthesis runs. Over time, these data points add up to meaningful project milestones met and completed with less downtime or resource waste.

    Direct Feedback, Continuous Improvement

    Manufacturing connects us not just with chemicals, but with the engineers, scientists, and logistics professionals building the future of many industries. Incoming feedback on product performance, application notes, or trace anomalies gets documented and analyzed by our plant team. This real-time loop allows for ongoing upgrades—whether it’s adjusting a reactor step, refining the drying stage, or tailoring a test method.

    Customer site visits, virtual inspections, and direct conversations have pushed us to improve packaging, transportation, and even aspects of our labeling for traceability. A persistent focus on listening means that the material evolves alongside the needs of those who trust it in their critical processes.

    Final Word

    Every shipment of N-Acetylanthranilic Acid bears the signature of our craftsmanship, rigorous quality controls, and decades of experience. Buying direct, customers receive a well-made, dependable intermediate that performs exactly as expected, batch after batch, under the conditions their processes require. In a competitive field crowded by resellers and third-party handlers, we stand by our role as the original producer—committed to reliability, growth, and open partnerships for the work ahead.