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N-(4-Acetylphenyl)-2,5-Dimethylpyrrole

    • Product Name N-(4-Acetylphenyl)-2,5-Dimethylpyrrole
    • Alias 4'-Acetyl-2,5-dimethylphenylpyrrole
    • Einecs 695-529-4
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    138664

    Chemical Name N-(4-Acetylphenyl)-2,5-Dimethylpyrrole
    Molecular Formula C14H15NO
    Molecular Weight 213.28 g/mol
    Cas Number 128199-50-2
    Appearance Solid (typical for organic compounds, actual form may vary)
    Solubility Soluble in organic solvents like chloroform and dichloromethane
    Purity Typically >95% for lab-grade material
    Structural Formula C1=CC(=CC=C1NC2=CC=C(N2)C)C(=O)C
    Iupac Name 1-(4-(2,5-Dimethyl-1H-pyrrol-1-yl)phenyl)ethan-1-one
    Storage Conditions Store in a cool, dry place, protected from light
    Hs Code 2933.99
    Density Estimated 1.1-1.2 g/cm³ at 20°C

    As an accredited N-(4-Acetylphenyl)-2,5-Dimethylpyrrole factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 10-gram amber glass bottle with a tamper-evident cap, labeled “N-(4-Acetylphenyl)-2,5-Dimethylpyrrole, 10g, for laboratory use only.”
    Shipping N-(4-Acetylphenyl)-2,5-Dimethylpyrrole is shipped in tightly sealed containers, protected from light and moisture. It is typically transported under ambient conditions, following standard regulations for non-hazardous laboratory chemicals. Appropriate labeling and documentation are included to ensure safe handling and compliance with shipping guidelines. Handle with care to avoid spills or exposure.
    Storage Store **N-(4-Acetylphenyl)-2,5-Dimethylpyrrole** in a tightly sealed container, protected from light and moisture, in a cool, dry, and well-ventilated area. Keep away from sources of ignition, acids, and oxidizing agents. Ensure appropriate labeling and use secondary containment if necessary. Follow standard laboratory safety protocols and local regulations for chemical storage.
    Application of N-(4-Acetylphenyl)-2,5-Dimethylpyrrole

    Applications of N-(4-Acetylphenyl)-2,5-Dimethylpyrrole in Industrial Manufacturing

    N-(4-Acetylphenyl)-2,5-Dimethylpyrrole serves as a specialized intermediate in select chemical manufacturing sectors. Its molecular properties make it a recurring component for advanced organic synthesis, dye technology, and high-performance material engineering. Below we detail its established usages in progressive downstream industries, each illustrated with sector-specific compliance standards, precise dose guidance, formulation steps, and the corresponding output types.

    1. High-Performance Pigment Synthesis for Automotive Coatings

    This compound addresses the demand for stable, high-chroma synthetic pigments within the automotive coatings sector. It reacts during azo coupling or oxidation stages to introduce intense coloration and improved UV resistance in high-durability paint systems, contributing substantially to premium finish requirements for vehicle exteriors.

    Industry compliance standards

    • ISO 12944 for corrosion protection of steel structures by protective paint systems
    • REACH annex XVII restrictions for colorants and additives in paint
    • GMI (General Motors Internal Specifications) for exterior color fastness and durability
    • ASTM D3022: Standard for Automotive Refinish Coatings

    Typical usage ratio

    • In pigment precursor batches: 0.8–3.0% by weight, adjusted according to the target pigment concentration and shade intensity in the masterbatch formulation

    Downstream process integration

    • Introduced during diazotization and coupling phases in pigment manufacture, followed by filtration, drying, and dispersion in polymer resins for paint blend preparation

    Final product types

    • Automotive OEM topcoats
    • Scratch-resistant refinishing paints
    • UV-stable car body coatings
    • Industrial vehicle exterior lacquers

    2. Advanced Electronic Material Intermediate (Organic Semiconductors)

    With its conjugated structure, the compound participates as an essential building block for synthesizing organic semiconductor compounds in next-generation electronic materials. Downstream users leverage its reactivity for fabricating thin-film transistors and flexible display substrates, where high charge mobility and film consistency are prioritized for device function.

    Industry compliance standards

    • IPC-4101D/98 for base materials used in electronics
    • IEC 61249-2-51 for halogen-free materials in electronic laminates
    • RoHS 2015/863 for restricted substances in electrical equipment
    • JEDEC JESD22-A103 for thermal cycle testing in semiconductor device qualification

    Typical usage ratio

    • Commonly 1.2–2.5% by weight within monomer polymerization streams, depending on the desired oligomer chain length and electrical property targets

    Downstream process integration

    • Engaged during the monomer functionalization and polycondensation stages, followed by solution casting or spin-coating onto substrates, then annealing for device assembly

    Final product types

    • Organic field-effect transistors (OFETs)
    • Flexible organic light-emitting diode (OLED) display panels
    • Printable electronic circuitry
    • Thin-film sensor arrays

    3. Specialty Dye Intermediate for Technical Textile Applications

    The compound’s aromatic acetyl and pyrrole motifs enable tunable chromophoric groups, facilitating its role as an intermediate for synthesizing high-washfast synthetic dyes used in technical textiles. Restricted shade migration and improved bonding to synthetic fibers are achieved, particularly in high-performance applications such as uniforms and protective clothing.

    Industry compliance standards

    • OEKO-TEX Standard 100 for harmful substance content in textiles
    • ZDHC MRSL 3.1 regulatory limits for dye residuals in wastewater
    • ISO 105-C06 for color fastness to washing
    • EN ISO 20105-X12 for color fastness to rubbing

    Typical usage ratio

    • Added at 0.5–1.6% by weight in dye synthesis pots, adjusted for fiber compatibility and targeted exhaustion percentage

    Downstream process integration

    • Employed during diazo coupling reactions, post-processed via purification and blending into colorant dispersions for textile dyeing or printing baths

    Final product types

    • Technical polyester and polyamide yarns
    • Workwear and protective textile coatings
    • Industrial carpet and upholstery fabrics
    • Heat-resistant dye prints

    4. Organic Chemical Intermediate for Pharmaceutical Impurity Markers

    Researchers and QC teams use this compound as a marker and intermediate for synthesizing custom reference impurities and related substances in regulated pharmaceutical development. Its predictable fragmentation pattern supports impurity profiling studies as required in active pharmaceutical ingredient (API) manufacturing support, particularly in pyrrole-based drug development programs.

    Industry compliance standards

    • ICH Q3A/B: Impurities in new drug substances and products
    • USP <467> Residual Solvents
    • EU Pharmacopoeia 5.10 for impurity control
    • cGMP (ICH Q7) for API manufacturing traceability

    Typical usage ratio

    • Control batches: 0.05–0.3% by weight when spiked for chromatographic method validation; scale adjusted by batch and target impurity reference concentration

    Downstream process integration

    • Integrated into stepwise synthesis of reference standards, followed by HPLC or LC-MS analysis and controlled isolation alongside API process validation runs

    Final product types

    • Pharmaceutical impurity reference standards
    • Custom analytical controls for QC laboratories
    • Validation samples for regulatory dossiers
    • API process development intermediates

    5. Performance Polymer Additive in Specialty Plastics

    This chemical serves as a functional additive in the manufacture of engineering plastics requiring enhanced stability or tailored optical properties. Its presence improves polymer matrix compatibility and introduces customizable interactions with visible and UV spectra, serving niche requirements in electronics housings and specialized packaging substrates.

    Industry compliance standards

    • UL 94 for plastics flammability rating
    • ISO 11357 for polymer thermal analysis
    • RoHS 2 Directive for restricted substances in plastic parts
    • EN 1886 for mechanical resistance in plastics used for technical enclosures

    Typical usage ratio

    • Blended at 0.6–2.0% by weight in the masterbatch melt, adjusted for required color strength and thermal durability

    Downstream process integration

    • Added directly to the polymer compounding phase, followed by melt extrusion, pelletizing, and subsequent injection or blow molding

    Final product types

    • Electronic device casings with color precision
    • UV-inhibiting packaging films
    • Custom technical plastic panels
    • Anti-static and decorative polymer sheets
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    Certification & Compliance
    More Introduction

    N-(4-Acetylphenyl)-2,5-Dimethylpyrrole: A Direct Perspective from Our Chemical Plant

    Knowing a Molecule by the Labor Behind It

    We work every day with N-(4-Acetylphenyl)-2,5-Dimethylpyrrole in our plant, so any words about this compound come shaped by the practice of actual synthesis, not just from catalogs or datasheets. Over the years, a team learns the peculiarities of each product. With N-(4-Acetylphenyl)-2,5-Dimethylpyrrole, the familiarity grows from repeated batches and hands-on monitoring, where coloration, yield, and crystal structure leave their marks on one's sense of chemical possibility. This isn't a compound lifted by marketing language; it’s a result measured by each chemist who’s filtered, dried, and analyzed it after a seven-hour shift on the line.

    Practical Understanding Over Abstract Data

    At our facility, a substance earns its respect by proving reliable throughout the actual process, not by looking good on paper. With N-(4-Acetylphenyl)-2,5-Dimethylpyrrole, we’ve come to trust its behavior through years of direct handling. What marketers might call “batch consistency,” we recognize as straightforward predictability in melting point, freedom from residue, and low presence of side products even after scale-up.

    In our bays, teams tend to mark each shipment of this material not only by lot number but also by memory of the process quirks it demanded. Our raw data show minimum deviation in purity, and every so often, an older technician will recount improvements made by switching process solvents or optimizing the workup temperature. That dialogue, between production experience and laboratory curiosity, sits at the root of how we see quality: precise, repeatable, and lacking excuses. This approach shapes our approach to every order, regardless of end use.

    Specifications Seen Through Real Production

    N-(4-Acetylphenyl)-2,5-Dimethylpyrrole comes as a solid, usually off-white to pale yellow, with physical traits that depend on both its synthesis and its purity. Drying is delicate, since even a hint of moisture can complicate storage for labs and downstream synthesis alike. In our workflow, the product’s melting point reads between 122 and 125°C, checked with standard apparatus and confirmed batch to batch in our in-house lab. Purity, by HPLC, stays above 98.5%, and the only time this value slips is when suppliers up the pressure for lower-cost intermediates—something we refuse to allow into our batches.

    Each drum and jar gets filled in a designated clean room, where trace contaminants like dust, oil, or fingerprint smudges get removed by habit as much as instruction. There’s no tolerance for vague assurances about “high purity”; a technician knows if the crystallization looks off or if the NMR spectrum tells a different story from the certificate. Our process labs run checks for related impurities, with particular attention to regioisomers and oxidized side products. Customers developing sensitive syntheses—especially those in pharmaceuticals and advanced materials—notice the effort, since the reactivity of pyrrole derivatives makes even minor contaminants a headache.

    Where This Compound Finds Its Place

    Roles for N-(4-Acetylphenyl)-2,5-Dimethylpyrrole evolve as research and applications grow. The structure—pyrrole backbone with acetylation and methyl substitutions—brings a unique platform for further functionalization or for direct assembly in material science. Synthetic chemists often turn to this molecule as a precursor or intermediate for heterocyclic compound production. Its ready N-acetylphenyl group links well in Suzuki and other coupling reactions. In some research settings, it shows promise for developing advanced dyes, electronics, or pharmaceutical building blocks.

    End users tell us they value how smoothly this compound reacts—controlled acylations and condensations, with minimal byproduct. That confidence in reactivity comes not from some theoretical promise, but because our product arrives clean, with low residual solvents and absent problematic trace metals. We hear from teams working with organic semiconductors, who count on stable and predictable chemical profiles when building their molecular frameworks. The direct feedback loop between production and application becomes essential, since the requirements for a pilot-stage R&D lab and a full-scale manufacturer differ, and the compound must serve both well.

    Understanding the Differences: Not All Products Bear the Same Signature

    In the chemical market, a catalog number never tells the whole story—something we learned again and again through exchanges with industry partners. N-(4-Acetylphenyl)-2,5-Dimethylpyrrole, regardless of source, carries a set of invisible fingerprints from its route of synthesis. Subtle differences—solvent choice, temperature control, purification practice—leave their signature. Our own protocol relies on a carefully chosen set of reagents, minimized exposure to atmospheric oxygen, and a single-step purification that removes the most troublesome side products in one go. We tweak conditions when needed, but never at the expense of reproducibility.

    Competing materials sometimes suffer from rush-job shortcuts—improper washing, incomplete drying, or careless packaging. These shortcuts may bring lower cost upfront but quickly turn into costly troubleshooting when impurities interfere with downstream transformations. Our customers have noticed: repeat orders come back not through flashy discounts, but because our product integrity shows itself in the lab. Every gram tells the history of its origin—bonded over heat and time under the watchful eyes of experienced staff. Our approach may appear old-fashioned, but we find that steady hands on the process serve the end user better than shortcuts.

    Comparisons with Common Alternatives

    Years of working with different pyrrole derivatives give us steady perspective on where N-(4-Acetylphenyl)-2,5-Dimethylpyrrole stands apart. Its acetylphenyl substitution, paired with the two methyl groups on pyrrole, alters both reactivity and solubility. Consider the simpler N-phenylpyrrole or even unsubstituted pyrroles: both act as raw building blocks, but neither introduces the same combination of steric hindrance and electron distribution. Laboratories sometimes buy similar-sounding compounds, on the assumption of broad interchangeability. Chemically, the difference becomes clear with reaction rates and selectivity. We’ve seen researchers sidestep troublesome byproducts by opting for compounds made by hand with these subtle but crucial modifications.

    Among the pyrroles, variations in substitution pattern influence everything from melting point to processability. The acetyl’s electron-withdrawing character, plus the methyl groups’ steric contribution, lead to smoother behavior in certain coupling reactions and functionalizations. Chemical plant personnel sum it up in stories—one senior operator recalls batches of a closely related pyrrole tending to form oily residues after long shelf times, while our preferred compound stays dry and manageable. These properties do not show up in abstract tables, but in everyday handling: faster weighing, easier dissolution, and cleaner chromatographic separation in downstream synthesis.

    A Manufacturer’s View on Challenges and Solutions

    Maintaining the purity and batch-to-batch similarity for N-(4-Acetylphenyl)-2,5-Dimethylpyrrole hinges on scrupulous process discipline. Every few months, we see issues like slightly off-color crystals or small reductions in yield, driven by minor fluctuations in raw material quality or ambient humidity. The team responds not with guesswork, but with side-by-side trials and immediate process checks. We rarely trust outside suppliers’ claims without verification. For example, a change in solvent supplier prompted a run of failed crystallizations; the solution came through a series of small-batch trial syntheses, each monitored for impurity loadout and handled only by those with practical experience.

    Regulatory issues touch every step of manufacturing. Downstream pharmaceutical users demand rigorous traceability and tight control over impurities. Our response is to go above regulatory minimums—auditing every steps from waste disposal protocols to documentation procedures. Working closely with analytical chemists, we keep tabs on trace solvents and unknowns, constantly seeking ways to further pare down impurity profiles. Equipment is cleaned with verified protocols, not just industry-standard checklists. Waste is minimized as much by process planning as by end-of-pipe treatment. Across the plant, these habits translate into fewer batch anomalies and less wasteful downtime.

    Feedback from the Front Lines

    Over time, real users—technicians, lab managers, researchers—bring forward observations impossible to predict from chemical theory alone. Occasional changes in crystal morphology, batch coloration, or dissolution time prompt phone calls, emails, and sometimes on-site visits. Each issue gets tracked and, more importantly, folded into ongoing process improvement. Drawing from direct feedback, we have refined drying steps, adjusted packaging to improve shelf life, and provided detailed impurity data so customers know what’s below detection. The open flow of communication, encouraged on both sides, allows us to improve incrementally, and ensures our compound serves its purpose.

    Appreciation from research chemists often centers on peace of mind: a drum shipped last month performs just like one from two years ago. This seemingly basic outcome takes persistent, attentive work at every level of the operation. We avoid surprise excursions in water content by regular instrument calibration and proactive maintenance. Packaging has moved from outdated secondary containers to modern, inert-lined drums that prevent subtle contamination. None of these efforts show up in price lists, but they matter to those scaling up or pushing the limits of chemical synthesis.

    Supporting Progress with Substance, Not Slogans

    Working daily with a product like N-(4-Acetylphenyl)-2,5-Dimethylpyrrole builds a sense of its real-world value. We’ve watched as it moves from lab curiosity to staple in certain segments of the materials and pharmaceutical development worlds. Key strengths—steadfast purity, minimal reactivity surprises, and approachable handling characteristics—grow not from hollow promises, but from hands-on refinement. We support laboratories moving from gram to kilogram quantities by talking straight about potential scale-up challenges, offering practical guidance about process modifications, and standing behind the product through customer trials.

    For those used to wading through recycled catalog copy, it’s hard to explain how firmly plant experience grounds a judgment. Each time a process engineer calls in with a strange behavior in a new synthesis, our staff draw from collective memory—past batches, oddball reactions, what worked and what was a dead end. This institutional memory cannot be borrowed or pretended, it emerges only from direct daily handling.

    Future Direction: Adjusting to Change, Holding to Standards

    Chemistry, as practiced on the plant floor, follows the pulse of new application fields. Researchers push for tighter specifications, lower trace metals, or different solubility profiles, and these requests roll in just as process realities hit. We keep up by adopting new analytical methods, investing in staff training, and fostering an organizational culture where speaking up about process drift is just as expected as clocking in on time. Experience tells us small shortcuts spiral into bigger costs down the line, so we weigh the cost-benefit at each proposed process tweak.

    Supply chain volatility creates its own array of headaches. For instance, a global shortage of a key starting material forced us to vet two new suppliers, changing nothing in the spec other than a couple points of impurity in the pre-synthetic stage. We flagged these differences right away, redesigned the purification steps, and ran extra analyses to assure the customer of no functional impact. It takes steady nerves—and honest dialogue—to admit when a raw material change risks altering the final product, but there’s no substitute for transparency. Most customers value facts over platitudes, so we stick to output that matches experience rather than spinning a story.

    Chemistry’s Demands: Meeting High Bars, Every Batch

    The market for advanced specialty chemicals leaves no space for half-finished jobs or wishful thinking. In our own facility, every kilogram of N-(4-Acetylphenyl)-2,5-Dimethylpyrrole arrives in customer hands after scrutiny over cleanliness, reactivity, and stability. The chain from reaction flask to labeled drum includes not only process engineers but maintenance crews, analysts, and even packers, all of whom add their own checks against error or contamination. We find this distributed responsibility creates fewer bottlenecks and more pride in shipment quality.

    Customers rely on this substance for novel research, sensitive coupling reactions, or pilot plant emission-reducing solutions. These ends require qualities visible not just to the eye but to the instrumentation: purity, consistency in physical properties, and simplicity in handling. Everything else follows—no amount of post-synthesis packaging or documentation can recover from sloppy upstream work. Chemists know; those who trust our batches do so because they’ve seen smoother results and less downtime. In a business governed by test tubes, columns, and spectra, consistency counts as much as innovation.

    Direct Accountability: Delivering on Earned Trust

    We see ourselves not just as a source of N-(4-Acetylphenyl)-2,5-Dimethylpyrrole, but also as stewards of its performance in the field. Each batch becomes a handshake with every researcher, formulation chemist, or production manager who depends on the outcome. Reputations ride on details—spotless batches, accurate documentation, responsive technical support. Mistakes, rare as they have become, get treated not with excuses but direct effort toward root cause analysis and future-proofing.

    The combined expertise on our plant teams—across process development, analytical chemists, operations, and R&D support—backs up every shipment. Their collective knowledge, tested with each new challenge, keeps us honest and the product fit for its roles. Direct communication, rooted in candor and facts, builds the enduring link between maker and end user. We prefer this model—where open acknowledgment of both strengths and setbacks leads to solutions more robust than any glossy description.

    Listening to the Market, Leading by Example

    Feedback from customers provides the single biggest driver for progress. Both critical comments and praise get handled with care. Too many companies hedge with delays and deferrals; our crews rally around reported issues, diving into root-cause determination and following through to resolution. Product improvements have stemmed from small discoveries—better drying protocols here, alternate packaging there, and always more precise analysis data, made available without hedging or sales spin.

    Logistics gets its own share of challenges. We’ve dealt with customs holdups, unpredictable shipping delays, and that one time a sealed drum developed a leak in transit after months of issue-free service. Rather than blame the carrier, we adopted a system of spot random drop tests and even more robust seals. The learning: changes in workflow stem from firsthand reporting, not policy abstracted to tick-boxes.

    Energy Behind the Guarantee

    Making N-(4-Acetylphenyl)-2,5-Dimethylpyrrole is not just about selling a compound, but upholding a history built on honest labor and deep chemistry know-how. Our staff take pride in the outcome, and we know that this substance carries potential weight in pharmaceuticals, electronics, and beyond. Connection with every downstream user steers our ongoing improvements—not endless feature lists but tangible reliability batch to batch. Experience keeps us alert to common pitfalls and empowers us to promise not the cheapest, but the best value over time.

    Ongoing updates in global regulation, analytical methods, and customer expectations spur us to keep up—not through superficial overhaul, but daily, incremental, plant-level changes. Each challenge, each setback, leaves new knowledge, and each solution offered builds a stronger bond with those who depend on us for performance they can document and rely on. Only through hands-on effort and honest reflection do we maintain a product that serves the evolving needs in modern synthesis and material sciences.