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N-(2-Methoxyethyl)Methylamine

    • Product Name N-(2-Methoxyethyl)Methylamine
    • Alias N-Methyl-N-(2-methoxyethyl)amine
    • Einecs 205-486-5
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    456512

    Cas Number 141-91-3
    Molecular Formula C4H11NO
    Molar Mass 89.14 g/mol
    Appearance Colorless liquid
    Odor Amine-like
    Density 0.892 g/cm³
    Boiling Point 115-117 °C
    Melting Point -93 °C
    Solubility In Water Miscible
    Flash Point 38 °C (closed cup)
    Refractive Index 1.421
    Vapor Pressure 12 mmHg (20 °C)

    As an accredited N-(2-Methoxyethyl)Methylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250 mL amber glass bottle with secure screw cap, chemical label displaying hazard pictograms, product name, and supplier information.
    Shipping N-(2-Methoxyethyl)methylamine should be shipped in tightly sealed containers, stored upright in a cool, well-ventilated area away from heat and incompatible substances. It is classified as a flammable liquid and may require special labeling and documentation per hazardous material transport regulations (e.g., DOT, IATA). Handle with suitable protective measures.
    Storage N-(2-Methoxyethyl)methylamine should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from incompatible substances such as strong acids and oxidizers. Keep away from sources of ignition and heat. Store under inert atmosphere if possible. Proper labeling and secondary containment are recommended to prevent leaks or spills. Avoid prolonged exposure to air and moisture.
    Application of N-(2-Methoxyethyl)Methylamine

    Applications of N-(2-Methoxyethyl)Methylamine in Industrial Manufacturing

    N-(2-Methoxyethyl)Methylamine serves as a key intermediate and building block across several specialized chemical industries. Our extensive production experience ensures reliable quality and batch-to-batch consistency for applications where purity and precise specification greatly impact downstream manufacturing. Below, we detail its most significant and documented uses in industrial sectors.

    1. Synthesis of Pharmaceutical Intermediates

    Pharmaceutical manufacturers utilize this amine as a critical alkylating and aminating agent in the production of active pharmaceutical ingredient (API) intermediates for select cardiovascular, anti-infective, and neurological medications. The amine group introduces a methoxyethyl side chain that improves the solubility and reactivity of various core structures, supporting efficient coupling and substitution reactions. Production processes typically require tight control over residual solvent, primary amine content, and enantiopurity, which are ensured by stringent in-process checks and batch traceability implemented at our facility.

    Industry compliance standards

    • ICH Q7 GMP for Active Pharmaceutical Ingredients
    • US Pharmacopeia (USP) general monographs where applicable
    • European Pharmacopoeia (Ph. Eur.) relevant general chapters
    • FDA 21 CFR Part 211 for finished pharmaceuticals

    Typical usage ratio

    • 3–12% by molarity relative to parent substrate; ratios optimized according to the target API synthetic route and reaction scaling

    Downstream process integration

    • Introduced during intermediate alkylation or acylation phases, typically under controlled temperature and pressure with continuous in-line monitoring for purity and yield

    Final product types

    • Antihypertensive drug intermediates
    • Cephalosporin precursor chemicals
    • CNS disorder medication synthons
    • Antiviral intermediate compounds

    2. Agrochemical Active Ingredient Manufacturing

    Producers of modern agricultural chemicals employ N-(2-Methoxyethyl)Methylamine to introduce alkylamino functionality into active ingredients. Its use enables the formation of novel herbicides and fungicides. Careful monitoring of impurity levels and byproducts is essential to satisfy registration requirements in major crop-protection markets. Our on-site analytical facilities and well-defined impurity controls enable reliable supply for these demanding formulations.

    Industry compliance standards

    • FAO/WHO specifications for pesticide ingredients
    • EPA 40 CFR Part 180 (tolerances and exemptions for pesticide chemical residues in food)
    • ISO 9001:2015 Quality Management System
    • REACH Regulation (EC) No 1907/2006 registration

    Typical usage ratio

    • 5–18% by weight, adjusted based on the formulation of target herbicide or fungicide active ingredient

    Downstream process integration

    • Employed during primary amination or chain extension stages of agrochemical synthesis, either in batch or continuous process settings; pre-purification required for regulatory compliance

    Final product types

    • Selective herbicides for cereal and broadleaf crops
    • Systemic fungicidal actives
    • Growth regulator intermediates
    • Seed treatment compounds

    3. Synthesis of Specialty Polyurethanes

    N-(2-Methoxyethyl)Methylamine is an established chain extender and functionalizing amine in the manufacture of specialty polyurethanes for automotive coatings, elastomers, and high-resilience foam. Its unique structure modulates polymer flexibility and bonding characteristics, promoting finely tuned mechanical and chemical properties. Our production batches supply consistent purity, which directly affects the reproducibility of end-use polyurethane performance as required by high-value segments.

    Industry compliance standards

    • ISO 9001:2015 for quality management in chemical synthesis
    • Automotive OEM material specification (where supplied for OEM use)
    • Methylene diphenyl diisocyanate (MDI) and polyol regulatory limits
    • RoHS compliance for electronics-adjacent foam applications

    Typical usage ratio

    • 2–10% by weight within total isocyanate/amine blend, optimized for the hardness, elasticity, and curing profile required by each polyurethane system

    Downstream process integration

    • Dosed during prepolymer formulation or direct in situ mixing step, providing adjustable chain extension or post-functionalization in bulk polymerization or cast foam processes

    Final product types

    • Automotive clear coats
    • Flexible memory foam
    • Elastomeric sheeting for heavy-duty use
    • Specialty high-gloss industrial coatings

    4. Water Treatment Agent Synthesis

    Manufacturers of advanced water treatment chemicals employ N-(2-Methoxyethyl)Methylamine as a primary amine reactant in the synthesis of non-ionic and amphoteric surfactants for use in industrial and municipal water purification systems. Stringent controls over trace metal and organic contaminants are applied in our production to satisfy the high demand for water treatment agent safety and downstream environmental approvals.

    Industry compliance standards

    • NSF/ANSI 60 for chemicals used in drinking water treatment
    • EPA Safe Drinking Water Act (SDWA) regulations
    • ISO 14001:2015 for environmental management
    • REACH compliance for export to the European Union

    Typical usage ratio

    • 1.5–7% by weight in surfactant synthesis; actual dosage subject to functional group density and batch scale

    Downstream process integration

    • Added during etherification or amidation phases of surfactant production, followed by deionization and further purification to meet end-use water contact standards

    Final product types

    • Reverse osmosis membrane cleaning agents
    • Scale inhibitor blend components
    • Municipal water clarification aids
    • Industrial effluent dispersants

    5. Solvent and Additive Production for Electronic Materials

    Within the electronics materials sector, specialized solvent and additive formulations incorporate N-(2-Methoxyethyl)Methylamine to adjust viscosity, improve adhesion, or promote surface modification for photoresists and electronic pastes. Manufacturing demands involve rigorous assessment of ionic contamination, micro-particulate content, and consistent dielectric profiles, which we maintain through advanced analytical testing and documented supply chain management.

    Industry compliance standards

    • IPC-4552/IPC-4553 standards for printed circuit chemical processes
    • SEMATECH guidelines for semiconductor chemical purity
    • RoHS Directive 2011/65/EU (Lead, Mercury, Cadmium restrictions)
    • ISO 14644-1 for cleanroom production environments (as relevant)

    Typical usage ratio

    • 0.5–5% by weight, selected for targeted performance improvement in photoresist, dielectric, or adhesion promoter formulations

    Downstream process integration

    • Blended during premix or post-polymerization phases of electronic material compounding, followed by filtration and quality review prior to shipment to PCB or wafer fabrication lines

    Final product types

    • Photoresist formulations for lithography
    • Non-conductive pastes for microelectronics
    • Dielectric ink additives
    • Surface treatment fluids for semiconductor substrates
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    Certification & Compliance
    More Introduction

    N-(2-Methoxyethyl)Methylamine: Manufacturer Insights and Industrial Applications

    Building Reliable Chemistry from the Ground Up

    In the world of specialty amines, N-(2-Methoxyethyl)Methylamine stands out for good reason. From our production lines, we witness daily how its structure—featuring the 2-methoxyethyl sidechain—brings new options to formulators and engineers who run up against the limits of traditional methylamines. Lab work confirms what plant data continues to show: swapping a simple alkyl for the ether-linked chain in this molecule changes reactivity, solubility, and volatility in ways that no substitution can quite match. We’ve seen this translate directly into measurable process improvements, cost savings, and fewer hazards for operators across a range of industries.

    Our Manufacturing Commitment: Purity, Consistency, and Traceability

    From raw materials sourcing to in-line monitoring, our manufacturing team focuses on the hallmarks that matter most to formulated products—batch-to-batch consistency and impurity control. Every batch of N-(2-Methoxyethyl)Methylamine, produced under tight process parameters, delivers a typical purity of 99% or higher by GC methods, and water often comes in below 0.5%, thanks to our vacuum dehydration step and closed-system handling. Residual methylamines and byproducts challenge less rigorous processes, but automated analytics and regular calibration keep side-products at trace levels in our material, which pays off downstream—for example, where surfactant synthesis or active pharmaceutical ingredient (API) manufacture demands confidence about incoming feedstocks.

    Recognizing N-(2-Methoxyethyl)Methylamine’s Unmatched Chemical Versatility

    We have seen how the subtle flexibility introduced by the 2-methoxyethyl group opens new doors, far beyond what methylamine or even dimethylamine can achieve. The molecule blends a balance of nucleophilicity and moderate steric profile. As a consequence, reaction yields in both pharmaceutical intermediates and agrochemical synthesis rise when process engineers can swap out less soluble, more volatile amines with our product. Where amines without ether tails fall short in solubility, N-(2-Methoxyethyl)Methylamine dissolves efficiently in alcohols, ethers, and polar aprotic solvents, giving it an edge in multi-solvent processes and systems where precipitation or phase separation once limited output.

    Different by Design: Comparing to Conventional Amines

    We get many questions from process engineers about why this specific amine is preferable in tough syntheses. Methylamine and ethylamine—workhorses for bulk chemistry—act as good nucleophiles, but their high volatility leads to odor emission, challenging storage, and increased workplace controls. In comparison, the boiling point of N-(2-Methoxyethyl)Methylamine sits noticeably higher. Operators can handle it more safely, and bag losses or evaporative waste fall.

    Performance tells the rest of the story. Our customers in coatings and textile auxiliaries often report improved solubility for their intermediates. Polyurethane producers see more even curing and less risk of bubble formation because our amine’s reactivity index fits right between slow secondary amines and highly reactive primary amines. The oxygen atom in the sidechain increases hydrogen bonding with polyols and epoxy resins. Instead of modifying the backbone of their recipes, formulators can fine-tune hardness, flexibility, and cure speed by adjusting loadings. This versatility gives chemists more control, which results in tighter product specs, lower rework rates, and easier regulatory compliance.

    Specifying N-(2-Methoxyethyl)Methylamine: How Purity Shapes Outcomes

    In practice, technical grade N-(2-Methoxyethyl)Methylamine often meets most requirements, but we produce several lots each year aimed at the pharmaceutical industry where trace impurities—formaldehyde adducts, residual chlorides, and secondary amines—matter. These are detectable at low ppm levels with modern LC-MS equipment. Our analytical team validates every lot with retention time and fragmentation pattern. Over the years, we’ve responded to custom requests for even tighter control, running our own pilot reactors to optimize salts removal, or reworking crystallization steps when a process design calls for a specific impurity profile.

    We see the request for electronic-grade specs growing as well, especially in printed electronics and advanced battery materials. A few parts per million of certain nitrogenous byproducts can upset surface behavior or catalyze side-reactions on electrode assemblies. Our R&D team uses staged distillation—over multiple columns at controlled pressures—to fine-tune output when standard synthetic routes don’t make the cut.

    Real-World Performance: Feedback from Manufacturers

    Formulators in the textile finishing sector report faster penetration rates in dyeing baths when switching from other amines to ours. Dye pickup improves, wash-fastness scores rise, and foaming during set-up falls. These are not theoretical gains—they show up as reduced rework and measurable increases in throughput. In semiconductor support fluids, chemists point to lower ion contamination and decreased residue on finished wafers. Here, the low halide content and minimal ammonia trace in our product heads off costly defects. Even agrochemical blenders find that our controlled impurity levels cut the variability in active loading from crop protection formulations, allowing them to register finished goods more smoothly with regulators in demanding markets like the EU and Japan.

    Practical Handling and Storage

    N-(2-Methoxyethyl)Methylamine needs careful but straightforward handling to maintain its quality. Our drums, equipped with lined vents, minimize contact with atmospheric moisture, cutting out water pickup and hydrolysis over time. We document headspace values for each shipment, letting clients confirm that our amine ships well below its recommended storage threshold. On larger installations, bulk tanks use nitrogen blankets and dedicated transfer lines to keep each batch clean and fresh. If a customer ever runs into a material that doesn’t match spec, our technical support team draws on decades of hands-on experience to audit in-house sampling and suggest practical fixes, not abstract cautions or vague process steps.

    Understanding the Chemical’s Impact in Diverse Applications

    Our product’s reputation in pharmaceutical synthesis stems from years of stable isotope labeling and side-chain modification work. When specializing in heterocycle assembly or fine-tuning stereoselective reductions, our clients see less byproduct, faster reactions, and purifications that do not stall out due to persistent color or odor. For surfactant blends, replacing more volatile amines with N-(2-Methoxyethyl)Methylamine reduces VOC emissions and lets engineers formulate with longer shelf life—technical improvements that compliance officers and plant managers recognize in audit results.

    In new energy material R&D, battery developers prefer this amine as a chain extender and surface modification tool for separator films and electrolytes. Its ether function helps anchor modifiers to PEG, PEO, and related polymers, where migration or volatility once led to cycle-life problems. The value lies less in conventional reactivity and more in the secondary interactions that researchers have documented, including hydrogen bonding and improved compatibility with fluorinated co-solvents.

    Reliable Supply—From Bulk to Lab Scale

    Shortages, shipping delays, and inconsistent quality can drag a well-planned project off track. Our direct manufacturing model—vertically integrated from key feedstocks through final packaging—keeps us in control of the supply chain. Strategic buffer stocks and regionally redundant production guarantee that clients see realistic lead times and straightforward tracking from raw materials to outbound cargo. We take orders from kilo-pack sizes to full ISO tanks, each labeled with their own lot histories and pre-shipment analytics. This approach pays off by minimizing out-of-spec incidents and giving procurement teams steady, trusted access to the amine they specify, every season and every market cycle.

    Tailoring Formulation Support: Where Industry and Lab Meet

    We routinely work with customer R&D teams to troubleshoot difficult reactions. The unique reactivity profile of N-(2-Methoxyethyl)Methylamine means a new blend or process can sometimes behave unpredictably. Our process chemists join on site, review real-time analytics, and offer concrete options. If a batch needs recovery due to off-spec color or trace amines, they provide detailed approaches for purification, rather than a generic summary. Over time, these industry-lab partnerships build recipes and processes that become company standards—not just for us, but for every plant using the material. We learn from batch records and pilot reactor runs, folding that feedback into future production cycles.

    Compliance and Forward-Looking Production

    Changes in environmental and workplace safety regulations guide our continuous improvement. In the past, the presence of free amines in some processes limited solvent recovery or increased site ventilation needs. We responded by optimizing synthesis pathways that reduce headspace losses and generate less offgas per ton of product. Our compliance staff frequently meets with external auditing agencies to document batch histories, impurity profiles, and traceability data directly from in-plant logs. Engineers use this information to strengthen client audits or support new registration dossiers where full backward trace is demanded.

    On the sustainability front, we invest in closed-loop solvent recovery and byproduct valorization. Waste amines from our process are recycled into boric acid neutralization or, after purification, blended into less sensitive downstream uses. This means that for every kilogram shipped, the environmental footprint shrinks—something we track using internally set metrics and adjust as new best practices emerge. When customers develop new “greener” amine chemistry, our R&D works in parallel to qualify alternative feedstocks—while verifying that changes do not introduce unexpected variability in our finished material.

    What Sets Us Apart—Experience and Direct Control

    As manufacturing chemists, we work each day at the intersection of fine chemical design and practical plant operation. We know the supply side—including raw material tightness and price volatility—can challenge even the best-laid R&D plan. Instead of outsourcing risk or offloading quality, we keep as much of the process in-house as possible. From hydrogenation conditions for methylamine synthesis to purification columns for final product, our team owns each loop. We stay accountable for the product’s story, not just its numbers on a spec sheet.

    We see process improvements as a long game—a series of feedback cycles between formulation chemists, plant operators, and end users. Our staff keeps batch logs on-site, tracking subtle changes in key metrics: GC peak ratios, HEADSPACE loss rates, salt content, and trace impurities. Only this level of detail allows us to deliver a product that stands up in critical regulatory audits and meets the emerging needs of process engineers who drive today’s specialty chemical markets.

    Supporting Knowledge Sharing Across the Industry

    Our in-house technical bulletins draw from day-to-day experience, not just standard protocols. We’ve published case studies on improved yields in oxazolidinone synthesis, reduced equipment corrosion in polyurethane foam manufacture, and lower dross in epoxy resin blending. What has emerged over the years is a network focused on facts—supporting both customer troubleshooting and internal best practices. Site tour visitors, from mid-level chemists to plant managers, tell us that real improvement comes from understanding what happens at each process stage—blending, reaction, separation, and packaging. We respond to market change by listening and by evolving our practices.

    The Future: Meeting New Challenges with Chemical Knowhow

    Applications for N-(2-Methoxyethyl)Methylamine continue to expand into life sciences, functional coatings, and energy storage. As battery and microchip manufacturers require ever-cleaner chemicals, our experience producing high-purity batches positions us to serve these frontiers without sacrificing reliability. Our research teams follow the latest synthetic and analytical methods, routinely cross-referencing published data with internal numbers and real-world feedback. This way, we don’t just react to shifts in client demand—we help pioneer them, bridging the best of basic chemistry with the realities of commercial-scale manufacturing.

    The market has a long memory for quality and reliability. Our team’s dedication to process detail, continuous knowledge sharing, and open engagement with evolving safety and environmental standards give customers more than just a product—they gain a partnership grounded in first-hand experience. In every drum and every new application, N-(2-Methoxyethyl)Methylamine demonstrates how practical chemistry, rigorous manufacturing, and attentive support can lift the standard for specialty amines across the industry.