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HS Code |
222347 |
| Chemical Name | N-(2-Hydroxyethyl)-N-Methylaniline |
| Cas Number | 698-44-6 |
| Molecular Formula | C9H13NO |
| Molecular Weight | 151.21 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 272-274 °C |
| Melting Point | -10 °C |
| Density | 1.056 g/cm3 (20 °C) |
| Refractive Index | 1.555 (20 °C) |
| Flash Point | 132 °C |
| Solubility | Soluble in water and organic solvents |
| Synonyms | 2-(Methylphenylamino)ethanol |
| Ec Number | 211-791-2 |
As an accredited N-(2-Hydroxyethyl)-N-Methylaniline factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle containing 500 mL of N-(2-Hydroxyethyl)-N-Methylaniline, securely sealed and labeled with hazard and storage information. |
| Shipping | N-(2-Hydroxyethyl)-N-Methylaniline should be shipped in tightly sealed, labelled containers, away from incompatible substances such as strong oxidizers. It must be packaged to prevent leaks and protected from physical damage. Follow applicable regulations for chemical shipping, including proper documentation, and ensure carriers are informed of chemical’s hazards. Store in a cool, dry environment. |
| Storage | Store N-(2-Hydroxyethyl)-N-Methylaniline in a tightly closed container in a cool, dry, well-ventilated area, away from heat, ignition sources, and incompatible substances such as strong oxidizers and acids. Avoid exposure to light and moisture. Clearly label the container, and ensure appropriate secondary containment and spill control measures are in place. Use appropriate personal protective equipment when handling. |
Applications of N-(2-Hydroxyethyl)-N-Methylaniline in Industrial ManufacturingAs a direct manufacturer of N-(2-Hydroxyethyl)-N-Methylaniline (HEMA), we serve a select group of downstream industries that rely on advanced intermediates for high-purity, value-added products. Below, we present a detailed overview of relevant application scenarios, specifying regulatory requirements, recommended formulation practices, position in the process flow, and the precise end-use products shaped by our customers’ technology platforms. 1. Dye Intermediates for Synthetic Dye ManufacturingMajor dye producers incorporate HEMA in the synthesis of azo, anthraquinone, and phthalocyanine dyes, leveraging its electron-donating profile for color strength modification and solubility enhancement. The industry has adopted this intermediate for batch and continuous processes that prioritize consistent tint and fastness properties across textile, leather, and paper coloration systems. High batch reproducibility and purity enable integration into mass-volume technical dye lines where only select intermediates meet quality and safety standards. Industry compliance standards
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2. Pharmaceutical Intermediate for Antihypertensive Drug SynthesisLeading pharmaceutical plants utilize HEMA as a key intermediate in synthesizing specific beta-blocker and antihypertensive APIs. The molecule’s unique structure facilitates alkylation steps under controlled conditions, supporting high-yield intermediate formation without side impurities. API manufacturers prefer in-house synthesis using HEMA to meet traceability, impurity profile, and quality control mandates imposed by global regulatory authorities. Industry compliance standards
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3. Corrosion Inhibitor Component for Industrial Cooling SystemsProducers of specialty water treatment formulations select HEMA as a part of multi-component corrosion inhibitor blends targeting closed-circuit cooling towers and recirculating water systems. The compound enhances passivation films on steel and copper surfaces, offering consistent protection under alkaline pH and variable water chemistries. Manufacturing teams optimize the loading of HEMA to balance efficacy against regulatory limits on amine-based organics in discharge waters. Industry compliance standards
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4. Developer Agent in Photographic Chemical ManufacturingManufacturers of traditional photographic developer solutions and specialty imaging chemicals employ HEMA as a secondary developing agent to modify reduction potential and contrast response. Controlled addition during emulsion processing steps prevents fogging and allows precise adjustment of grain structure, supporting advanced photographic and X-ray films. Only high-purity lots meet the demanding consistency and shelf-life specifications of global film and imaging brands. Industry compliance standards
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5. Stabilizer in Polyurethane ProductionPolyurethane foam and elastomer manufacturers integrate HEMA as a chain stabilizer and antioxidant agent during the formulation of specific flexible and microcellular foams. The compound supports molecular weight control at prepolymer stage, minimizing yellowing and oxidative degradation over service life. Plants with dedicated automotive and bedding foam lines require customized loading levels and strict lot-trace documentation for compliance with international consumer safety requirements. Industry compliance standards
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N-(2-Hydroxyethyl)-N-Methylaniline carries distinct attributes that set it apart from other substituted anilines. Over many years, we have handled this product and seen its performance in a wide range of reactions and end-use scenarios. Designed as a secondary aromatic amine, this compound fits neatly into sectors that require both basicity and hydrophilicity in the same molecule. Its unique chemical arrangement grants it a valuable place for manufacturers of dyes, intermediates, surface modifiers, and specialty resins.
This compound’s chemical structure, C9H13NO, incorporates both a methyl group and a 2-hydroxyethyl group attached to the nitrogen atom of the aniline core. The thoughtful combination ensures a balance between water compatibility and organic solubility. Not all aniline derivatives show this profile—many lack the hydrophilic hydoxyethyl group and demonstrate weaker interaction with polar solvents. Through direct experience in practical synthesis, we observe reduced volatility and greater formulation flexibility compared to straight-chain alkyl substitutes. Handling and dosing operations in the plant benefit from this difference, even during temperature fluctuations or under variable batch conditions.
In our daily operations, purity holds priority because downstream reactions depend on clean intermediates. Pure N-(2-Hydroxyethyl)-N-Methylaniline, by our standard runs, appears as a clear, pale yellow liquid, free from solid inclusions. We keep free amine content low and minimize colored by-products. Purity consistently reaches above 99% (by GC) in regular production batches, and water content stays well below 0.2%. This degree of control has direct consequence: manufacturers who use our material find less rework and greater batch-to-batch reliability in their own chemical transformations.
On the technical side, the compound displays a boiling point in the vicinity of 265°C. This feature allows integration into processes that involve elevated temperatures. Flash point sits around 144°C, so standard chemical manufacturing protocols for amines remain adequate for safe storage and handling. Viscosity remains low enough to support simple pump transfer or gravity feed, even in cool conditions. This trait becomes important during bulk unloading or large-scale blending, reducing the risk of line blockages or flow problems during colder months.
N-(2-Hydroxyethyl)-N-Methylaniline’s major end use remains as a key intermediate for dye synthesis. In azo dye production, the compound forms colorless or yellowish diazonium salts that couple smoothly with other aromatic partners. The hydroxyethyl group gives dyestuffs improved brightness and water solubility. Over time, we have partnered with both textile pigment formulators and inkjet dye developers—both groups rely on consistent purity and reactivity. They routinely confirm that our material enhances fastness, especially in water-based inks, compared to dyes made from unsubstituted aniline or methyl-aniline.
In polymer and coating chemistry, the compound performs as a chain intermediate and helps optimize the crosslink density of specialty resins. Many customers have shared that the resulting polymers show better flexibility and chemical durability. Paint and coating facilities, especially those focused on protective films and adhesives, increasingly use our product for its wetting properties and its ability to boost adhesion. They see measurable reduction in defect rates on non-polar substrates like polyethylene or polypropylene.
Our technical teams regularly discuss process integration with formulators. They note that N-(2-Hydroxyethyl)-N-Methylaniline brings strong nucleophilic properties to the table, making it easier to create custom molecules in both laboratory and production settings. It often serves as a practical alternative to N-methylaniline in reactions where solubility presents an obstacle. End-users who make plasticizers, surfactants, and specialty lubricants notice improved distribution of functional groups, leading to more homogeneous final blends.
Over decades, we have manufactured a range of substituted anilines. Those familiar with N-methylaniline or monoethanolamine will see N-(2-Hydroxyethyl)-N-Methylaniline’s structure as a thoughtful hybrid. While N-methylaniline delivers high reactivity for aromatic substitutions, its lack of a hydroxy functional group limits use in aqueous systems. On the other hand, monoethanolamine offers strong water solubility but far less aromatic character. By joining the desirable aspects of both, N-(2-Hydroxyethyl)-N-Methylaniline bridges a key gap.
Many researchers and production chemists choose this product when they need both organic backbone and enhanced water interaction. Where pure N-methylaniline can impart unwanted odor and toxicity concerns, our product emits a milder scent and typically carries a lower risk profile—backed by substantial plant air monitoring data. Operators frequently ask us about downstream by-product formation. Through real production runs, we’ve confirmed that fewer nitroso and nitro impurities form in diazotization steps compared to legacy mono-substituted anilines.
In storage and logistics, we know N-(2-Hydroxyethyl)-N-Methylaniline stores more stably than other amine derivatives. Product color stays consistent even after months of storage under standard warehouse conditions. Tanks and drums remain cleaner on draining, and fewer resinous deposits build up. These practical advantages mean lower maintenance for blending lines or finished goods tanks, and less downtime for plant cleaning crews.
The chemical sector now places far greater emphasis on environmental regulations and lifecycle impact. We witnessed a sharp increase in regulatory scrutiny, especially for aromatic amines, over the past decade. Our site worked closely with environmental consultants and local authorities while updating our production protocols. N-(2-Hydroxyethyl)-N-Methylaniline’s relatively lower toxicity profile helped it remain on approved lists in many markets even as tighter discharge and exposure limits took hold.
Through years of emissions monitoring, we found that this compound biodegrades more completely under standard wastewater treatment than analogues with longer or more branched alkyl substituents. Our plant effluent data show that well-managed neutralization and activated carbon methods remove nearly all residuals before discharge. We invested in on-site containment measures, and customer audits regularly validate our responsible stewardship. This track record matters to buyers facing increasingly stringent supply chain audits and customer sustainability requirements.
Recyclability marks another crucial aspect. In multi-use chemical manufacturing, waste minimization makes or breaks the cost equation. We routinely reclaim off-spec or spent batches through vacuum distillation and solvent extraction, sending less than 0.1% of incoming raw material to final disposal. Customers know they can blend recyclable material with virgin stock without compromising performance in high-purity applications. In a marketplace where resource and emissions efficiency drive purchasing decisions, attributes like these carry genuine weight.
On the ground, the safe handling of N-(2-Hydroxyethyl)-N-Methylaniline relies on operator familiarity and adherence to robust procedures. Long exposure studies, both from our plant and academic research, confirm that this compound poses moderate irritation if handled with bare skin or allowed direct contact with mucous membranes. We equip all process lines with closed transfer systems, minimize vapor exposure, and perform regular spot testing around pump stations and blend tanks.
Team training emphasizes immediate clean-up of minor leaks and prompt replacement of gloves, goggles, and other PPE. We offer practical training based on actual incidents, not textbook hypotheticals. Our warehouse staff and loadout crews report few incidents after implementing improved secondary containment and clear labeling systems. Each safety bulletin incorporates lessons learned from real handling, including near-misses, so that error potential drops each year.
Our approach avoids broad-brush claims or simple checklists—we fine-tune safety information each year based on detailed data tracking and feedback. We schedule medical surveillance and emergency response drills frequently, with direct plant-level management oversight. These efforts ensure incidents stay rare and minor, supporting both workforce health and the uninterrupted flow of quality product to our customers.
Operational consistency stands as a daily challenge. Even small variations in raw material purity or storage temperature can shift reaction yields far downstream. We overcame these issues by introducing in-line monitoring at key process stages, which picks up impurity trends or color changes within seconds. The investment paid off directly in fewer off-spec batches and quicker customer deliveries.
Supply chain interruptions occasionally disrupted feedstock supplies, especially during geopolitical or logistics crises. To counteract this, our team dual-sources precursors from both local and international producers. Holding sufficient safety stock prevents downtime. Over time, we developed tank-level prediction algorithms that learn from consumption patterns and seasonal swings, so procurement keeps step with demand. Customers have reported steadier inventory and shorter lead times as a direct result.
Waste reduction remains a constant target. Solvent recovery improves both economics and sustainability, but only when impurities stay controlled. We maintain a close-loop system where spent solvent cycles back repeatedly, with periodic purification runs and impurity purge. Chemical reactors run with precise temperature and pressure control, based on learnings from years of pilot and plant operation. This focus keeps both variable costs and environmental footprints in check, supporting compliance and competitive pricing.
Customer needs in sectors like dye manufacture or specialty surfactants rarely stay static for long. We stay closely attuned by providing technical support, fast turnaround on sample requests, and real-time data sharing for product trials. Many long-term customers have participated in “open plant” visits, comparing notes on blending, product quality, and process optimization. These collaborations help overcome unexpected obstacles, such as micro-scale impurity formation or subtle changes in reactivity tied to process upgrades.
Feedback from industry partners often drives innovation in our batch process design. One example came from an inkjet dye producer facing trace precipitation in cold storage conditions; within a month, we fine-tuned a filtration step and tightened moisture specifications across all batches. This flexibility, rooted in daily production reality, sets supplier-manufacturers apart from traders or distributors without hands-on exposure. Through open dialogue and shared analytical resources, both parties achieve better outcomes with fewer surprises.
Our company culture rewards engagement at every level, from the lab bench to the tank farm. Staff submit process improvement ideas that get regular review and, when validated, rapid adoption. Plant-level learnings often lead to smoother product integration downstream. For instance, adjustments in blending protocols reduced foaming incidents during dye coupling for multiple textile manufacturers. We freely share non-confidential process insights, so users avoid common missteps and get full value.
We remain active contributors to peer groups and technical associations focused on specialty chemicals and environmental responsibility. Through these forums, we stay ahead of market trends and regulatory shifts before they reach crisis stage. We employ in-house regulatory specialists who track evolving standards for aromatic amines and translate requirements into language that supply chain managers and line chemists can act on. This anticipatory approach means users of N-(2-Hydroxyethyl)-N-Methylaniline avoid costly compliance delays and can adjust formulas in step with market demand.
Demand for multi-functional aromatic amines continues to climb. Digital inks, smart coatings, and green chemistry applications each require tighter product control, clearer traceability, and stronger environmental performance than ever before. To stay ready, we invest in resin compatibility studies, new trace analysis methods, and predictive process control. Our R&D team works alongside commercial partners to test innovative blending agents and process aids that will raise the bar for N-(2-Hydroxyethyl)-N-Methylaniline’s utility and overall performance.
As new electrolytes, surfactants, and specialty polymers reach pilot plant or launch phase, customers count on clear, unfiltered communication from the actual manufacturer. We meet this standard through open test results, plant audits, and collaborative troubleshooting. Where market needs shift, we realign both in-house resources and supply partnerships, aiming for stable quality and competitive lead times even in volatile conditions.
Direct experience with N-(2-Hydroxyethyl)-N-Methylaniline, from day-to-day manufacturing to hands-on customer support, shapes every aspect of our operation. We listen closely to those who rely on this material, deliver only thoroughly tested batches, and address both technical and regulatory questions based on real data. Through constant improvement, careful stewardship, and transparent partnerships, we ensure this product remains a trusted building block for innovation in dyes, resins, and specialty chemical markets worldwide.