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N-(2-Hydroxyethyl)Ethylenediamine-N,N',N'-Triacetic Acid Trisodium Salt

    • Product Name N-(2-Hydroxyethyl)Ethylenediamine-N,N',N'-Triacetic Acid Trisodium Salt
    • Alias HEDTA-Na3
    • Einecs 239-332-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    481035

    Chemical Name N-(2-Hydroxyethyl)Ethylenediamine-N,N',N'-Triacetic Acid Trisodium Salt
    Common Abbreviation HEDTA-Na3
    Molecular Formula C10H13N2Na3O8
    Molecular Weight 370.19 g/mol
    Cas Number 139-89-9
    Appearance White to off-white powder
    Solubility In Water Highly soluble
    Ph Of 1 Percent Solution Approximately 8.0-9.5
    Storage Conditions Store at room temperature, tightly sealed
    Applications Chelating agent
    Melting Point Decomposes before melting
    Synonyms Trisodium N-(2-hydroxyethyl)ethylenediamine-N,N',N'-triacetate
    Stability Stable under recommended storage conditions
    Pubchem Cid 85110
    Shelf Life 2-3 years under proper storage

    As an accredited N-(2-Hydroxyethyl)Ethylenediamine-N,N',N'-Triacetic Acid Trisodium Salt factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The chemical is packaged in a 500g white plastic bottle with a blue screw cap and tamper-evident seal, labeled with product details.
    Shipping N-(2-Hydroxyethyl)Ethylenediamine-N,N',N'-Triacetic Acid Trisodium Salt should be shipped in tightly sealed containers, protected from moisture and direct sunlight. Store in a cool, dry place during transit. Ensure appropriate labeling and packaging according to chemical safety regulations. Avoid contact with incompatible substances, and handle with standard chemical shipment precautions.
    Storage **N-(2-Hydroxyethyl)ethylenediamine-N,N',N'-triacetic acid trisodium salt** should be stored tightly sealed in a cool, dry, well-ventilated area away from moisture, direct sunlight, and incompatible substances such as strong acids and oxidizers. Keep the container clearly labeled and away from food and drink. Avoid excessive heat and contact with skin or eyes. Store at room temperature unless otherwise specified by the manufacturer.
    Application of N-(2-Hydroxyethyl)Ethylenediamine-N,N',N'-Triacetic Acid Trisodium Salt

    Applications of N-(2-Hydroxyethyl)Ethylenediamine-N,N',N'-Triacetic Acid Trisodium Salt in Industrial Manufacturing

    N-(2-Hydroxyethyl)Ethylenediamine-N,N',N'-Triacetic Acid Trisodium Salt, widely recognized as a high-performance chelating agent, serves essential roles in various industrial manufacturing processes requiring advanced metal ion control. Below, we outline verified downstream uses across multiple industries, detailing integration stages, compliance standards, dosage guidance, and resulting finished goods derived from its application. All scenarios reflect current industrial practice based on customer feedback and market adoption.

    1. High-Purity Cleaning Solutions for Semiconductor Fabrication

    Semiconductor manufacturers rely on this compound to control trace metal contaminants during wafer and equipment cleaning, supporting defect-free circuit patterns at the nanometer scale. The chelating strength enables stable removal of calcium, iron, and heavy metal ions from process baths, sustaining bath integrity and reducing yield losses.

    Industry compliance standards

    • SEMI S2 Environmental, Health, and Safety standard for Semiconductor Manufacturing Equipment
    • ISO 14644 Cleanroom Standards
    • IEC 60749 Test methods for semiconductor devices
    • ASTM E2314 for process chemical purity

    Typical usage ratio

    • 0.02% – 0.15% w/w in aqueous cleaning baths; dosage tailored to specific metal ion contamination profile and system volume

    Downstream process integration

    • Dosed directly into recirculated wet-chemical baths used for wafer cleaning after photolithography or etch steps, typically controlled inline via conductivity or metal ion sensors

    Final product types

    • Ultra-pure silicon wafers
    • High-performance microchips (logic ICs, DRAM, NAND)
    • Compound semiconductors (GaAs, SiC, etc.)
    • Plasma etching equipment components after post-process cleaning

    2. Industrial Water Treatment for Boiler and Cooling Systems

    This chelating agent enables precise control and sequestration of hardness ions and trace metals in industrial water cycles, reducing scaling, corrosion, and fouling risks in both closed-loop boiler and large-scale cooling tower systems. It fits requirements for continuous and batch water replenishment, proving essential in power generation and manufacturing facilities.

    Industry compliance standards

    • ASTM D5127 for high-purity water
    • ASME Boiler & Pressure Vessel Code Section VI
    • EU REACH regulation for water additives
    • Quality Management System: ISO 9001 for water chemical manufacturing

    Typical usage ratio

    • 2 – 10 mg/L depending on feedwater scaling tendency, system metallurgy, and makeup water hardness

    Downstream process integration

    • Introduced into feedwater tanks or directly metered into recirculation lines post-filtration, often managed by automated dosing pumps linked to real-time water quality monitors

    Final product types

    • Demineralized process water supplied to steam boiler systems
    • Water-cooled heat exchangers with extended lifecycle
    • Cleaned wastewater meeting discharge limits
    • Protective maintenance chemical blends for industrial plants

    3. Pulp and Paper Bleaching Process Stabilization

    Paper mills use this compound primarily during the hydrogen peroxide bleaching stage to chelate and neutralize trace iron and manganese, both of which catalyze peroxide decomposition and degrade pulp brightness. The result is lower bleaching agent loss, improved pulp quality, and reduced environmental load from residual metals.

    Industry compliance standards

    • CEPI (Confederation of European Paper Industries) Quality Standards
    • TAPPI T236 for chlorine-free bleaching agents
    • REACH registration for process chemicals
    • ISO 14001 Environmental Management in pulp production

    Typical usage ratio

    • 0.05% – 0.12% on dry pulp weight, adjusted based on incoming wood species and raw water composition

    Downstream process integration

    • Added in-line prior to peroxide or other oxidative bleaching steps; dosing controlled to maintain desired redox environment and minimize metallic catalyst concentration

    Final product types

    • Brightened chemical pulp for printing paper
    • Kraft pulp for food-safe packaging
    • Tissue and hygiene paper treated for stability and color
    • Bleached specialty paper grades

    4. Formulation of Detergents for Industrial Textiles and Institutional Laundries

    Large-scale laundries and textile facilities incorporate this agent to boost detergent cleaning capacity by binding calcium, magnesium, and transition metals. This action reduces fabric graying, supports stain removal using lower surfactant content, and extends the life of commercial textiles exposed to repeated washing cycles.

    Industry compliance standards

    • EU Detergent Regulation (EC) No 648/2004
    • OEKO-TEX Standard 100 for textile chemical safety
    • ISO 4312 Performance Testing for detergents
    • REACH compliance for laundry auxiliary chemicals

    Typical usage ratio

    • 0.1% – 0.3% w/w in detergent concentrate, with adjustment based on local water hardness and target fabric load

    Downstream process integration

    • Blended into the aqueous phase during batch production of detergent bases, commonly paired with enzyme and optical brightener premixes, then diluted for finished size package

    Final product types

    • Commercial laundry detergents for hotel and hospital linens
    • Alkaline cleaners for industrial workwear
    • Industrial textile cleaning agents for dye houses
    • Concentrated institutional cleaning liquids

    5. Electroplating Process Baths for Metal Surface Treatment

    Specialty metal finishing shops employ this compound as a complexing agent to maintain precise metal ion activity during copper, nickel, and zinc electroplating. Its tailored sequestration of interfering ions prevents unwanted precipitation, supporting uniform deposit formation and enhanced product appearance.

    Industry compliance standards

    • ISO 6158 for electroplating quality
    • RoHS Directive 2011/65/EU for restricted substances in plated products
    • ASTM B322 for cleaning metals prior to electroplating
    • REACH compliance for electroplating additives

    Typical usage ratio

    • 0.03% – 0.09% by bath volume depending on deposition current density and operating metal concentration

    Downstream process integration

    • Incorporated into plating solution make-up or as part of regular bath maintenance, balanced against other complexing agents and pH adjusters with periodic laboratory verification

    Final product types

    • Corrosion-protected automotive fasteners
    • Plated connectors for electronics
    • Decorative hardware finishes
    • Industrial machine components with wear-resistant coatings

    6. Chelation Component in In-Vitro Diagnostic Reagents

    Diagnostic reagent formulators utilize this chelator to maintain enzyme activity and reagent stability, particularly in complex assay buffers for biochemical analyzers. Its capacity to bind trace metals minimizes analytical drift and false positives in colorimetric and immunochemical testing.

    Industry compliance standards

    • IVDR (EU 2017/746) In Vitro Diagnostic Regulation
    • ISO 13485 for medical device quality management
    • CLSI (Clinical Laboratory Standards Institute) guidelines
    • Good Manufacturing Practice (GMP) for diagnostics

    Typical usage ratio

    • 0.005% – 0.025% in diagnostic buffer preparations; ratio determined by target assay requirements and potential background interference

    Downstream process integration

    • Added to liquid or lyophilized reagent base formulations during bulk buffer preparation, pre-mixed before the inclusion of enzymes, antibodies, or detection substrates

    Final product types

    • Automated clinical chemistry assay kits
    • ELISA buffers for laboratory testing
    • Point-of-care diagnostic strip reagents
    • Multiplex immunoassay solutions
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    Certification & Compliance
    More Introduction

    N-(2-Hydroxyethyl)Ethylenediamine-N,N',N'-Triacetic Acid Trisodium Salt: Insights from Our Manufacturing Floor

    Understanding the Substance Through Experience

    Each day, our teams walk the manufacturing floor surrounded by stainless steel vessels, precise instrumentation, and a steady hum of chemists' conversations. Among the products that come off our line, N-(2-Hydroxyethyl)Ethylenediamine-N,N',N'-Triacetic Acid Trisodium Salt commands a unique kind of respect. This is not just a compound name you find in technical dictionaries – it’s a material we have watched grow in demand across multiple industries, especially as water quality and process reliability gain priority worldwide.

    Often shortened among our chemists as HEDTA-Na3, this trisodium salt stands out in our product lineup. From the earliest batches, it became clear that tiny changes in process variables—temperature adjustments, feed rates, raw material purity—affect its finished quality. A subtle shift can change appearance, solubility, and even reactivity, all of which our customers notice during critical steps in their own work. Through the lens of hands-on manufacturing, value appears not only in the specification sheet but also in the consistency and reliability batch after batch.

    Composition, Quality, and What Sets Our Product Apart

    We work with the trisodium salt form of N-(2-Hydroxyethyl)Ethylenediamine-N,N',N'-Triacetic Acid because its high solubility in water improves compatibility for industrial applications. Whether our customers are formulating water treatment blends or fine-tuning electroplating baths, ease of integration matters. Compared with many chelating agents, HEDTA-Na3 offers impressive stability with fewer side reactions in alkaline and neutral solutions.

    Physical properties are closely monitored as each grain, flake, or powder emerges from our reactors. Appearance ranges from white to off-white crystalline powder, sometimes with a slight odor rarely detected above normal laboratory background. Solubility is rarely an issue unless shipping conditions fail to protect packaging from excess moisture. In analytical testing, our QC staff routinely measures sodium, nitrogen, water, and heavy metal content, cross-checking against industry standards and earlier in-house results. We never underestimate the importance of lot-to-lot consistency. Even seasoned operators appreciate the subtleties between batches.

    Applications as Seen from the Factory Floor

    Over the years, customer requests and close discussions with end users have shown us where HEDTA-Na3 fits best. The most frequent applications remain in water treatment and detergent formulations, thanks to its robust ability to bind calcium, magnesium, iron, and trace metals. This chelation makes a measurable difference in preventing scale formation and improving cleansing by keeping metals suspended and away from sensitive surfaces.

    Electroplating specialists frequently seek out HEDTA-Na3 for nickel, copper, and allied baths. Our manufacturing teams tailor particle size and dryness to meet the specialty needs of these customers. Consistent particle structure prevents unwanted deposits or film defects on expensive substrates. In agriculture, we see growing interest in this compound for formulating micronutrient fertilizers. Its ability to keep iron and other ions bioavailable, despite changes in soil pH, supports healthier crop outcomes. Years ago, packaging was designed with durability in mind since field applications often exposed materials to variable climate conditions.

    Other sectors lean on HEDTA-Na3 for completely different reasons. Textile dye houses use this compound to minimize unwanted color changes, as the chelating agent suppresses metal-catalyzed dye shifts. Pulp and paper mills report improvements when using this chelator in bleaching steps, where metal-free processing supports higher-quality finished sheets. Even a small improvement in the removal of iron and manganese gives these operators a measurable edge against competing sources.

    Differences from Related Compounds

    We manufacture a range of chelating agents, so we see firsthand how HEDTA-Na3 lines up against similar compounds, especially the widely known EDTA and DTPA salts. In practice, HEDTA-Na3 offers distinctive chemistry due to the hydroxyethyl group on its backbone, which influences its chelating profile as well as its solubility in different pH zones. Some customers come in expecting EDTA-like results and quickly notice how the subtle structure changes performance in their application. HEDTA-Na3 maintains more stability in alkaline environments, reducing breakdown that would otherwise release bound metals back into solution.

    Comparing it directly with DTPA, we notice that while DTPA’s five acid groups grant stronger chelation, especially toward heavy metals, HEDTA-Na3 delivers a balance between chelating power and gentle interaction, making it valuable where over-complexation can interfere with downstream steps. Handling also differs: HEDTA-Na3 generally flows better and creates less dust, reducing exposure risks for operators. From a disposal perspective, customers frequently note that regulatory compliance is less demanding with HEDTA-Na3 since it is easier to biodegrade than some of its cousins.

    Throughout multiple production cycles, we have identified marks of quality that seasoned buyers recognize. HEDTA-Na3 rarely triggers the stubborn cloudiness in recirculating water loops seen with lower-grade or misformulated competitors. Its sodium content ensures reliable pH control as well, which becomes noticeable in sensitive electronic or pharmaceutical settings. The ability to source a single, properly reacted trisodium salt means smaller companies can scale up processes without introducing unnecessary adjustments or trial-and-error.

    Packing, Handling, and Storage Observations

    Packing lines at our facility run year-round, pushing out drums, sacks, and specialty bags designed to withstand rough handling and variable warehouse environments. We focus on internal liners to reduce risk of water pickup, and we train our staff to watch for even slight breaches. Even small amounts of caking from absorbed moisture can affect performance, especially in fine-particle grades destined for high-speed mixers. Repeated experience shows that short exposure to humidity quickly leads to clumping, so we recommend dry, shaded, and well-ventilated storage at all points from our plant to the end user.

    For bulk users, the single most common request centers around minimizing dust and maximizing flowability. Our engineering teams spent many months refining granulation and drying steps to balance easy handling with sufficient dissolution speeds. Real-world use often challenges theory — a formulation change at a detergent plant or a new regulatory requirement at a municipal water authority means we must pivot and fine-tune drying cycles or sieve calibrations on the fly.

    During warehouse walkthroughs, proper inventory rotation and pallet care stand out as key factors. Product left at the bottom of a stack or near moisture-prone doors may soften over time, risking changes in flow or color. Every truckload that exits our doors passes a final set of inspections to catch issues before they reach the customer. These practices help head off complaints and recalls, ensuring that product integrity remains high all the way through distribution.

    Supporting Innovation and Regulatory Demands

    Fielding inquiries from formulators, engineers, or environmental regulators comes with the territory as a manufacturer. Chemistry never stops changing; neither do the rules. Lately, environmental stewardship and occupational health standards have pushed us to commit more resources to tracking trace metals and organic impurities. Every year brings updates to permissible limits in various countries. Our analysts rerun validation tests as soon as standards shift, and any out-of-spec result triggers a hold and investigation.

    Some research partners need HEDTA-Na3 for applications pushing the boundaries of traditional chemistry. A recent collaboration with a wastewater treatment design firm led us to develop a purer, low-sulfate HEDTA-Na3 grade, fine-tuned for maximal removal of lead without fouling biological treatment stages. Sometimes, scientists share their data with us, chalking up a win for cleaner effluents and reduced environmental risk.

    Certain markets favor HEDTA-Na3 specifically for eco-label product development, looking for biodegradable chelants to support green chemistry claims. Our plant has installed online carbon monitoring and energy efficiency controls—not only to satisfy regulators, but also to reassure customers demanding a transparent supply chain. We document every processing variable and routinely share lifecycle assessments and product stewardship guidance with our partners. Years of facing audits have taught us that openness and traceability build more trust than simply posting certificates on a website.

    Lessons from Customer Feedback and Real-World Outcomes

    We measure our success not only by technical purity or meeting spec sheets but by following what happens after HEDTA-Na3 leaves our site. Years ago, an Asian water utility reported persistent mineral scaling and cloudy water despite dosing generic chelates. After switching to our high-purity HEDTA-Na3 grade, their lab logs showed cleaner pipes and longer intervals between maintenance shutdowns. Undetected impurities can make a world of difference. Clean running systems become a point of pride for both supplier and operator.

    Smaller companies often appreciate technical support and quick shipment more than any published property. Once, a customer developing micronutrient blends for greenhouses reached out with a challenge: unpredictable precipitation of iron in their tanks. Working together, our applications team and production chemists traced the cause back to a partner’s hard water source. A minor tweak in the sodium content of that batch stabilized the blend and improved their final crop yields.

    Customer stories reinforce that every shipment carries downstream consequences. Incomplete chelation, poor flow, or contamination creates headaches for production managers and engineers. We share real-world feedback in daily operations meetings, then adjust processes or documentation to help prevent repeat concerns. Making subtle adjustments on our lines keeps the next container that much more reliable.

    Balancing Technology, Economics, and Sustainability

    Every new process we evaluate for HEDTA-Na3 production factors in power usage, waste minimization, and raw material costs. The high purity needed in specialized electronic or biomedical applications often requires extra filtration or crystallization, extending run times and driving up expenses. Sourcing raw components at volume sometimes puts pressure on procurement, especially if material prices swing due to shortages or geopolitical shifts. We have learned to maintain strategic supplier relationships and invest in redundancy, preventing line stoppages.

    Waste minimization remains both a challenge and a priority. We recycle as much process water as feasible and track each waste stream for potential reuse in less sensitive applications, such as industrial effluent treatment. A steady output of technical-grade HEDTA-Na3 helps supply clients with fewer purity demands, avoiding downcycling to landfill wherever possible. We document these flows to satisfy audit requests and continuously improve, drawing on hard-earned lessons from past spills or off-spec batches.

    Customers care about not only what’s inside the drum but also how it was made. Power meters and solvent recovery systems dot our factory floor, and we keep a watchful eye on our greenhouse gas outputs. Where old technology dumped heat and lost solvent to the air, our upgraded systems trap and reuse resources. Field research groups sometimes visit and leave with deeper trust after seeing commitment in action, not just in marketing slides.

    R&D, Product Customization, and Collaborative Progress

    Production is never static. We regularly field requests for tweaks: lower sodium grades, higher-purity custom batches, or blends tailored for particular pH ranges or interaction with specific metals. Some customers need HEDTA-Na3 just beyond reach of our current specs, challenging us to push for new quality benchmarks and innovative crystallization approaches. Not every experiment pays off, but each attempt broadens our expertise.

    Working with customers to solve application-specific issues often means running parallel lab trials and pilot-scale test runs. In agriculture, for example, one group needed a version of HEDTA-Na3 that released micronutrients at a slower, temperature-controlled rate. Adjusting particle morphology and dryness, then scaling from pilot to full production, required dozens of test cycles and close communication. Success here provides a blueprint for rapid problem-solving in other industries.

    We see ourselves as more than just a supplier. Ongoing technical support, shared documentation, and full traceability let our partners innovate with confidence. It might be a new detergent blend or a tweak to an existing electroplating process—the trust grows as we share what we learn and adapt our manufacturing to push new frontiers.

    Embracing Change and Remaining Grounded

    Over decades, new regulations, shifting customer preferences, and ever-advancing science push us to refine our approach to manufacturing N-(2-Hydroxyethyl)Ethylenediamine-N,N',N'-Triacetic Acid Trisodium Salt. Our staff attends technical seminars and regulatory workshops, updating both process and paperwork in response. Internal training focuses as much on problem-solving as compliance. Mistakes happen, but a culture of learning brings ongoing improvements.

    As a direct manufacturer, we feel the urgency behind each request and every challenge. Technical innovation matters, but at the core, manufacturing is about delivering what our customers expect—clean product, reliable performance, and consistent support—every single time. In a world where even small contaminants in a batch can spoil tons of finished goods or halt production, a decade of consistency and trust grows into the strongest product endorsement possible.

    Looking to the future, we expect new uses and stricter regulations to shape how we produce, pack, and deliver HEDTA-Na3. Our experience remains our best guide. We navigate new requirements by drawing on what has worked, correcting course where needed, and maintaining close relationships with both suppliers and customers. As customers innovate, our teams will match those efforts, championing both chemistry and quality that drives industry forward without forgetting the lessons from every batch before.