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HS Code |
629395 |
| Chemicalname | N-(2-Chloroethyl)benzamide |
| Casnumber | 6149-44-8 |
| Molecularformula | C9H10ClNO |
| Molecularweight | 183.64 |
| Appearance | White to off-white crystalline solid |
| Meltingpoint | 92-94 °C |
| Solubility | Slightly soluble in water; soluble in organic solvents |
| Purity | Typically ≥98% (may vary by supplier) |
| Smiles | C1=CC=C(C=C1)C(=O)NCCCl |
| Inchi | InChI=1S/C9H10ClNO/c10-7-6-11-9(12)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,12) |
| Storageconditions | Store in a cool, dry place, tightly closed container |
| Hazardclass | Irritant; handle with appropriate safety precautions |
| Synonyms | 2-Chloroethylbenzamide |
As an accredited N-(2-Chloroethyl)Benzamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | White or amber glass bottle containing 25 grams of N-(2-Chloroethyl)Benzamide, tightly sealed, labeled with hazard and handling information. |
| Shipping | **Shipping Description for N-(2-Chloroethyl)Benzamide:** N-(2-Chloroethyl)Benzamide should be shipped in tightly sealed containers, protected from moisture and light. Transport in compliance with applicable regulations for hazardous chemicals. Ensure proper labeling and documentation. Use suitable secondary containment, and handle with appropriate safety precautions. Store at a controlled temperature, preferably in a cool, dry location during transit. |
| Storage | N-(2-Chloroethyl)benzamide should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from direct sunlight and sources of ignition. Keep it separate from incompatible substances such as strong oxidizers, acids, and bases. Store at room temperature, and ensure containers are clearly labeled. Avoid moisture and protect from physical damage. |
Applications of N-(2-Chloroethyl)Benzamide in Industrial ManufacturingN-(2-Chloroethyl)Benzamide serves as a specialized intermediate across select chemical sectors, offering targeted performance attributes central to finished product design. As a direct manufacturer, we supply this compound for integration into specific downstream formulations where traceability, regulatory compliance, and process reliability are mandatory. The following sections detail its certified uses in distinct industrial applications, outlining compliance, dosage, process position, and resulting end products. 1. Pharmaceutical Active Ingredient SynthesisThis compound plays a role as an acylating or alkylating agent in the selective stepwise synthesis of certain API scaffolds, notably in the preparation of intermediates for niche cytostatic medications. Operators introduce it in controlled batch reactors, directly influencing the molecular framework of onco-pharmaceutical actives. Strictly managed environments and protocol-driven documentation govern its handling at this production stage. Industry compliance standards
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2. Agrochemical Intermediate ManufacturingWithin crop protection chemistry, our material is deployed as part of multi-step synthesis for certain pre-emergent and post-emergent herbicide active ingredients. Its functional group incorporation impacts selectivity and metabolic profile of downstream actives. Downstream integrators operate continuous flow or multi-batch plants under regulatory scrutiny, ensuring trace impurity control aligned with product registration demands. Industry compliance standards
Typical usage ratio
Downstream process integration
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3. Specialty Fine Chemical SynthesisChemical synthesis manufacturers integrate N-(2-Chloroethyl)Benzamide as a key functionalizing agent in custom amide, ester, or nitrile intermediates for downstream plastics, resins, and specialty monomers. Producers rely on precise reactivity control and batch-to-batch reproducibility given the specificity of customers’ downstream customization parameters. Incoming quality documentation and batch segregation are standard. Industry compliance standards
Typical usage ratio
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4. Laboratory Chemical Reagent ProductionThis compound finds use in the formulation of analytical-grade reagents, particularly where selective acylation or alkylation reactions form part of test kit diagnostics or chemical reference material kits. Reagent manufacturers require comprehensive batch traceability, certificate of analysis, and impurity profiling aligned with lab protocols to support reproducible R&D and QC outcomes. Industry compliance standards
Typical usage ratio
Downstream process integration
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Rolling out N-(2-Chloroethyl)Benzamide in our production plant, we focus on doing more than just following a formula. For years, our team has researched, synthesized, and refined this compound for a diverse group of industries. We understand where the real strengths of N-(2-Chloroethyl)Benzamide come into play and why customers keep asking for it by model number: C9H10ClNO. Compared with generic offerings, every batch we manufacture answers directly to hands-on needs, not spreadsheet targets. Our story with this chemical goes beyond its molecular diagram. It’s about delivering a dependable product used in advanced synthesis, custom intermediates, and sometimes, for research into new chemical architectures that are not yet even announced in journals.
In the plant, we don’t just target minimum assay numbers. Each synthesis run is benchmarked against the parameters we’ve built up over years of scale-up and feedback from end-users. N-(2-Chloroethyl)Benzamide, by our standard, hits a purity specification that labs and production chemists can trust batch after batch. No one wants surprises in their reactions. Typical impurity profiles or minor byproducts are logged and controlled as part of our continuous process review. This rigorous approach shows its value when our customers scale a process from bench to reactor and keep seeing repeatable outcomes. That alone sets our product apart from some you’ll find just new to the market or repackaged by traders who haven’t seen what these small deviations can do to a process yield or performance profile.
Every chemist has their preferred intermediates, but the backbone provided by N-(2-Chloroethyl)Benzamide serves important functions in the pharmaceutical and specialty chemical sectors. We have witnessed customers use this compound for construction of molecules where the ethylene unit and amide bonds are integral to activity, and the chloro group opens the door to functionalization. Over the years, we’ve supported development projects in both batch and continuous flow regimes, always observing how subtle changes in moisture content, crystal size, or trace residual reactants impact downstream application. The benefit of producing this compound from scratch—not passing it along from a warehouse—lets us hold tight to the properties that matter most: shelf life stability, clarity of melting point, and precise physical form. These traits aren’t just checkboxes. They make a real difference in how smoothly new processes get up and running in both R&D and commercial settings.
No end-user wants mystery out-of-spec material turning up just when they need reliability. We set our specifications for N-(2-Chloroethyl)Benzamide to ensure it works precisely in the applications our customers demand—whether that’s introducing a chloroethyl side chain, building more advanced ring systems, or prepping for a reduction step. Production always starts from high-grade raw materials with tightly monitored trace mineral content; moisture control and post-synthesis drying are optimized at every stage. Each lot receives both HPLC and GC analysis to confirm minimal levels of off-main-chain byproducts—this has proven crucial for customers who run long, multi-step syntheses and can’t risk unexpected reactivity. Handling the entire synthesis and purification cycle in-house means faster response to process feedback and tighter resolution of any rare deviations. Investing in people who’ve experienced these processes firsthand builds confidence in quality claims—a subtle but real contrast to those who simply resell packaged product bought on the global market.
We have worked with a variety of functionalized benzamides and their analogs. Each one has its specialized roles, but rarely does another intermediate offer the clean, predictable behavior found in N-(2-Chloroethyl)Benzamide. For researchers constructing complex new molecules, the ethylene bridge and chloro group layout give selectively accessible sites. In our pilot plant, tests confirmed this structure provides superior feedstock yield compared to traditional mono-substituted benzamides, especially under basic or nucleophilic conditions. Colleagues reporting from pharmaceutical pilot suites have backed up those findings: using our compound, catalyst loading or downstream extraction adjusts with less tuning. Side product build-up—a running headache when using certain homologs—declines sharply. And for scale-up work performed under cGMP compliance, our tight handling of residual solvents and trace impurities slashes troubleshooting and delivers a distinctly lower rate of downstream failures.
Most trade houses simply hand over a drum with a certificate, but having direct control inside our synthesis line changes how problems get addressed. The amide bond formation step runs under proprietary conditions that we’ve sharpened over years, making the coupling reliable even as production ramps. Downstream purification strategies—built on both classic chromatography and engineered crystallization—drive batch clarity. By sticking with vertical integration, from raw material prep to finished product packing, the traceability chain stays intact. That’s not just for compliance. Whenever a customer flags a variable result, rather than chasing paperwork, our chemists can go back to the precise production logs, environmental profiles, and testing data associated with each batch. In the handful of cases where adjustment was needed, that transparency spiraled directly into a solution rather than a blame game between vendors. That real-world access to cause-and-effect shortens troubleshooting, giving clients real assurance not possible from trading middlemen.
From the beginning, we aimed to support real-world chemistry without making end users jump through hoops. Production chemists working at both small molecule and major pharmaceutical plants have pointed out lower rates of filtering and handling issues using our N-(2-Chloroethyl)Benzamide. Moisture-sensitive steps—once prone to exotherms or unstable intermediates—see tighter thermal control, cutting back on the time teams spend managing side reactions. When applied in custom synthesis for specialty agrochemicals, feedback repeatedly mentions decreased run times and higher final purity after basic aqueous workups. This gain traces straight to our process: low levels of unreacted starting material and tightly controlled crystal morphology. Universities using the compound for academic research speak to consistent NMR and mass spec profiles, which keeps results reliable for publication and scale-up funding. Having hands-on understanding of downstream transformations has shaped our handling, drying, and packaging approaches, and we regularly tweak these based on customer conversations instead of copying a competitor’s data sheet.
Safe handling and accurate paperwork count in regulated industries. Our own protocols grew from actual plant-floor needs and field use, not just written rules. Each lot ships with validated test results for impurity and residual solvent content, plus a detailed analysis report so that our users never guess about what’s coming into their plant or lab. Regular trace analysis for regulated solvent residues remains part of routine QA, and real-world safety learnings shape our user documentation. Handlers deserve more than boilerplate MSDS texts—they need guidance based on observed scenarios, such as how quick ambient shifts affect product stability or why certain protective equipment worked better during a prolonged campaign. As a direct producer, we listen fast if a user notes an unexpected outcome and feed that information back into process risk assessments, instead of brushing it off as a paperwork issue.
Our relationship with N-(2-Chloroethyl)Benzamide stretches from development runs for researchers all the way to scaled production campaigns destined for finished goods. Over years spent working alongside customers, we’ve been able to track how a truly stable and predictable intermediate leads to more wins. Pharma teams running late-stage process R&D noted increased confidence in route scouting; fewer headaches mean faster time to clinical trial submission. Fine chemical producers logging yield gains thanks to minimal waste find greater satisfaction in every drum—no more hunting for hidden contaminants or fighting to meet their own process cutoff points. Academic collaborators speak bluntly: accessing our consistent compound cuts down on the “unknown variable” which hinders their students’ projects and almost guarantees faster, more reliable results, especially where funding or tenure relies on steady, publishable data.
Standing in the same shoes as process chemists, we know how much a single “uncertain” lot of starting material can throw off an entire project timeline. A key difference in our N-(2-Chloroethyl)Benzamide is control at every step. Bulk suppliers or third-party distributors may deliver a workable basic amide, but experience in our own labs and those of our clients underscores why downstream issues—odd coloration, moisture spikes, fines that clog filtration—are much less frequent with our supply. While we don’t claim miracles, regular dialogue with users keeps our quality system focused on what actually matters: reliable reactivity, no surprises in storage, and a form that handles sensibly on scale-up. Even aspects like particle size or flowability become crucial in automated feed systems, and small improvements in dryness or packing density can show up in smoother, more stable operation at our customers’ sites. From bench-top trial all the way to tonne-scale commercial batches, these differences consistently matter day in, day out.
Over dozens of campaigns, feedback from lab and plant users drove an evolutionary process in how we manufacture N-(2-Chloroethyl)Benzamide. Early runs saw more variable color or slight batch-to-batch inconsistencies in handling—call it the price of learning with our own hands. But every flagged issue went straight onto our control charts and SOP updates. Adding in-line monitoring, batchwise crystallization tweaks, and more granular drying controls cut defects steadily. Now, whether the compound goes fresh for custom synthesis or sits in inventory for months, its properties hold true. Environmental testing, variations in storage temperature, and real shipping conditions have informed small but crucial tweaks, such as adding extra visual inspection or specialized packing liners for long-haul export. These changes wouldn’t have happened in a resale environment—real-world learnings count far more than copy-pasted certification from an unknown upstream factory.
N-(2-Chloroethyl)Benzamide offers much more than a stable chloroethyl addition. Synthetically, this intermediate gives process chemists a versatile lever: the chloro group activates specific alkylation or nucleophilic displacement routes, and the sturdy benzamide backbone tolerates a range of conditions where less robust analogs fall short. Customers report using our compound in iterative synthesis schemes for both medicinal chemistry and advanced materials. Whether building up heterocyclic rings, constructing linker units, or merging into more elaborate pharmacophore frameworks, repeat orders and ongoing feedback point to reliability. The ability of our in-house team to optimize for specific downstream needs—altering certain crystallization protocols or managing trace residuals—can make the difference between an easy campaign and an extended troubleshooting headache. Candid feedback sometimes points out tweaks that make a practical, not just statistical, difference in productivity at our customers’ sites.
Producing N-(2-Chloroethyl)Benzamide at the manufacturer level means never leaning too long on last year’s best practices. Every new project or market sector brings feedback that feeds future upgrades—whether it comes from an academic user flagging a hard-to-spot impurity, or an industrial process operator dealing with an unexpected freezing-point drop mid-transfer. Trading houses may pass along these stories, but without direct process insight, those observations rarely translate into action. Our QC staff involve production and process engineering in every material deviation or customer report; this leads to targeted preventive action and sharpens internal standards year by year. Raw material changes, synthesis step tweaks, or upgrades in analytical technology show up quickly in the field as improved reactivity, fewer handling issues, and tighter finished product specs. Instead of chasing lower price points, we work for sustainable repeatability—consistently delivering a material that helps our users meet their own KPIs smoothly.
N-(2-Chloroethyl)Benzamide often gets compared to other substituted benzamides or halogenated amides. These analogs might look similar in CAS number or structure, but bench testing and field experience show sharp distinctions in actual process behavior. Customers report that some other candidates introduce unpredictable side-chain reactivity or break down under standard synthetic conditions. In contrast, our compound’s particular electronic and steric profile gives clean, single-pathway reactivity, especially for nucleophilic displacement and SN2-type installations. Trace impurity control likewise matters: workups and isolations often run cleaner with our material due to tight upstream purification and moisture management. Competitor samples often fail to replicate this behavior, leading to accumulation of hard-to-remove byproducts or more frequent post-reaction cleanups—issues handed to us for root-cause review when clients switch suppliers and seek remedies. Our direct production oversight has routinely identified sources of what might seem like minor quality differences, but in scaled synthesis, these subtleties drive major bottom-line impacts.
Producing N-(2-Chloroethyl)Benzamide for such a varied field of customers taught us the actual difference made by a hands-on approach to manufacture. Every drum leaving our plant reflects ongoing attention to technical detail shaped by real use—not guesses or generic standards. Our team, informed by long-term partnerships with users ranging from academic synthetic groups to full-scale cGMP manufacturers, understands that success lives in every lot delivered with confidence: crystal consistency, reliable purity, and detail in documentation that stands up to regulatory or process scrutiny. Real chemistry, effective process support, and a steady feedback loop keep our product from drifting into mediocrity. Direct production oversight, ongoing process refinement, and respect for collaborative problem-solving ensure our N-(2-Chloroethyl)Benzamide delivers beyond numbers on a label. In the end, years at the bench and in the plant have taught us that true quality means knowing both the molecule and the people who depend on it, crafting each batch to meet needs as they evolve—one shipment at a time.