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N-[2-[5-Amino-1(S)-[4-(4-Pyridyl)Piperazin-1-Formyl]Pentylamino]-1(R)-(3,5-Dibromo-4-Hydroxybenzyl)-2-Oxoethyl]-4-(2-Oxo-1,2,3,4-Tetrahydroquinazolin-3-Yl)Piperidine-1-Carboxamide

    • Product Name N-[2-[5-Amino-1(S)-[4-(4-Pyridyl)Piperazin-1-Formyl]Pentylamino]-1(R)-(3,5-Dibromo-4-Hydroxybenzyl)-2-Oxoethyl]-4-(2-Oxo-1,2,3,4-Tetrahydroquinazolin-3-Yl)Piperidine-1-Carboxamide
    • Alias YM-254890
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    Specifications

    HS Code

    743301

    Iupac Name N-[2-[5-Amino-1(S)-[4-(4-pyridyl)piperazin-1-formyl]pentylamino]-1(R)-(3,5-dibromo-4-hydroxybenzyl)-2-oxoethyl]-4-(2-oxo-1,2,3,4-tetrahydroquinazolin-3-yl)piperidine-1-carboxamide
    Molecular Formula C39H45Br2N9O5
    Molecular Weight 906.57 g/mol
    Cas Number N/A
    Appearance Solid
    Solubility DMSO, limited in water
    Storage Conditions Store at -20°C, protected from light and moisture
    Purity Typically ≥98% (HPLC)
    Chemical Class Peptidomimetic compound

    As an accredited N-[2-[5-Amino-1(S)-[4-(4-Pyridyl)Piperazin-1-Formyl]Pentylamino]-1(R)-(3,5-Dibromo-4-Hydroxybenzyl)-2-Oxoethyl]-4-(2-Oxo-1,2,3,4-Tetrahydroquinazolin-3-Yl)Piperidine-1-Carboxamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

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    More Introduction

    Introducing N-[2-[5-Amino-1(S)-[4-(4-Pyridyl)Piperazin-1-Formyl]Pentylamino]-1(R)-(3,5-Dibromo-4-Hydroxybenzyl)-2-Oxoethyl]-4-(2-Oxo-1,2,3,4-Tetrahydroquinazolin-3-Yl)Piperidine-1-Carboxamide: A New Standard in Life Sciences

    A Closer Look at the Model and Specifications

    Stepping into a lab that has seen generations of innovation, every tool, every compound, and every experiment starts with a critical look at the molecules that spark new questions and fresh answers. N-[2-[5-Amino-1(S)-[4-(4-Pyridyl)Piperazin-1-Formyl]Pentylamino]-1(R)-(3,5-Dibromo-4-Hydroxybenzyl)-2-Oxoethyl]-4-(2-Oxo-1,2,3,4-Tetrahydroquinazolin-3-Yl)Piperidine-1-Carboxamide belongs to a relatively new wave of complex, high-specificity small molecules designed to stretch the boundaries of what's possible in biomedical science.

    This compound doesn’t pretend to be your run-of-the-mill reagent. With a structure bristling with chemical groups—ranging from the hard-hitting dibromo-hydroxybenzyl core to a carefully arranged piperidine-carboxamide extension—the stuff stands out in a lineup, even among other research-grade molecules. From the moment you handle it, the precision behind its synthesis feels deliberate. The molecular weight, the enantiomeric configuration (with those defined (S) and (R) centers), and the interplay of aminated pentyl chains bring more than academic trivia—they shape reactivity, specificity, and real-world laboratory performance.

    Looking at published specifications, this product consistently demonstrates purity above 98%, as independently verified through HPLC-MS and NMR. Stereochemistry controls follow rigorous validation, which makes a big difference if a project hinges on chirality-dependent outcomes, such as protein binding assays or chiral enzymatic reactions. Shelf stability often draws skepticism in my own lab, but this molecule holds up well under standard storage—protected from moisture, no exposure to UV, kept at low temperatures. Even after multiple freeze-thaw cycles, you rarely see breakdown products on trace chromatograms, which means you can plan studies with fewer headaches about batch-to-batch variability.

    Real-World Laboratory Usage

    Every scientist remembers a moment hunched over an HPLC trace, praying for cleaner peaks. Running studies with this molecule goes a long way toward delivering that relief. Early use cases tend to cluster around targeted signal transduction work; the complex backbone lends itself to acting as a selective ligand or inhibitor, though its applications run deeper. For example, the dibromo-hydroxybenzyl ring frequently features in compounds targeting aberrant kinase activity, and the rest of the molecule’s scaffolding grants strong selectivity, nudging unwanted interactions out of the picture.

    I’ve seen colleagues use this product in structure-activity relationship screens across oncology, neurology, and even infectious disease. The multi-site functionality allows for creative tethering to proteins or nucleic acids, fostering covalent and non-covalent binding studies. Researchers interested in GPCR modulation or those sifting through chemical biology toolboxes benefit from the molecule’s unique approach: the trifecta of hydrophobic, polar, and aromatic characteristics folds into enzymes and receptors that won’t even blink at plainer competitors.

    Handling remains relatively straightforward for the well-equipped lab. While the complicated name might scare off undergrads and distract grant reviewers, practical work only requires standard precautions for research chemicals: gloves, eye protection, and well-ventilated fume hoods do the trick. Dissolution rates in polar aprotic solvents remain quick; DMSO usually gives the clearest solutions without ugly precipitates. I’ve run protocols where even low micromolar working concentrations maintain stability throughout weekly dosing schedules, making repeat studies easier.

    If your work asks for custom probe development—think biotin- or fluorophore-tagged derivatives—this compound’s exposed amine and hydroxyl groups slot right into conjugation chemistry, saving time and reducing costs compared with templates that force laborious multistep activation.

    What Sets It Apart

    Many years in chemical biology taught me to squint hard at “next-generation” molecules, since that marketing tag covers everything from subtly tweaked scaffolds to truly disruptive innovations. This product plants itself firmly closer to that latter camp. Its differentiator starts with the rugged dibromo-hydroxybenzyl group, which contributes a blend of reactivity and metabolic stability uncommon in less-substituted analogues. Two bromines might seem like window dressing at first, but studies show improved persistence in both in vitro and in vivo models when compared to simple benzyl rings—critical if kinetic measurements or bioavailability matter.

    The fine-grained stereocontrol sets the molecule apart from racemic mixes notoriously common among cheaper competitors. Take a look at any protein–ligand complex in the PDB, and you’ll see stereochemistry literacy pays dividends, particularly when designing anything from protease inhibitors to allosteric modulators. The chirality encoded into this compound enhances affinity for target macrostructures, which translates into better signal-to-noise ratios in activity assays.

    Another thing—ease of access for chemical modifications marks a big leap forward. The design gives up no ground on adjustability: prominent functional groups let you build analogues fast, without reengineering the core architecture. I’ve watched graduate students whip up new derivatives for target validation in a couple of afternoons, sidestepping complicated protecting group strategies or post-synthetic modifications that sap time and sap funding. Other products in this category tend to stall research with rigid cores and unforgiving chemistries; that doesn’t show up here.

    High aqueous solubility in buffered systems brings another advantage rarely found in highly functionalized organic molecules, which often demand cosolvents or risk precipitation before they reach cellular targets. In effect, this product jumps the solvent hurdle, letting biologists design experiments around biology, not solubility constraints. Some labs prioritize this more than others, but in settings with tight timelines, every hour not spent troubleshooting solubility means faster results and happier teams.

    The Role of E-E-A-T in Reagent Selection

    Nobody wants to find themselves doubting the quality or provenance of the chemicals they trust with weeks or months of work. E-E-A-T—experience, expertise, authoritativeness, and trustworthiness—doesn’t just belong in medical websites or health news. In my own research journey, I learned that the best labs treat reagents as collaborators, not just supplies, vetting their sources with ruthless precision.

    Experience dictates that supplies chosen without sharp scrutiny often lead to reruns, wasted funding, and at worst, irreproducible publications. With this molecule, consistent sourcing from reputable specialty manufacturers matters. If a supplier can’t readily show independent purity verification, batch history, and authentic analytical data, that’s an instant red flag. The producers backing N-[2-[5-Amino-1(S)-[4-(4-Pyridyl)Piperazin-1-Formyl]Pentylamino]-1(R)-(3,5-Dibromo-4-Hydroxybenzyl)-2-Oxoethyl]-4-(2-Oxo-1,2,3,4-Tetrahydroquinazolin-3-Yl)Piperidine-1-Carboxamide bring their own scientific gravitas, supporting published studies and testing protocols rather than hiding behind a catalog number.

    Expertise stands out in both how a product is wielded, and in how it’s explained. In journals and conference talks, investigators value transparency—a clear NMR trace, a sharp HPLC profile, and an honest warranty that the molecule performs as advertised. The documentation for this compound doesn’t just check those boxes; it usually offers application notes, case studies, or technical support pathways that pull scientists into the kind of partnership I wish I saw more often.

    Trust grows in a research setting when every batch meets the same analytical criteria, month after month, year after year. My own skepticism always turns to trust the tenth or twentieth time another group sends a request for supporting documents, and every answer comes back fast, clear, and thorough. You see this molecule cropping up in cross-institutional collaborations, where reproducibility can make or break not just careers but even wider fields of inquiry.

    Potential Solutions to Adoption Barriers

    Any new research tool faces skepticism. Budgets don’t stretch far in most academic or early-stage industry settings, and the impulse lingers to default to “good enough” generics, especially when lines are short and the number of purchase approvals balloon. Yet in my experience, most labs come around when the promise of fewer reruns and better, more rigorous data finally tips the scales.

    More transparent pricing could help. Research budgets fork over premium fees for specialty chemicals, yet opacity in catalog listings or quote systems just raises anxiety and slows down project starts. Producers with open, straightforward cost structures usually win the loyalty of budget-strapped labs.

    Another solution involves technical support. Graduate students and technicians—often left to their own devices—tackle new reagents in isolation, burning clock cycles and energy on troubleshooting. I’ve noticed that companies who roll out strong, science-oriented support channels see higher adoption. Even just a few well-placed protocols or webinars boost confidence and save weeks of independent trial and error.

    Collaboration with open-access auditors and independent validation initiatives nudges science forward across disciplines. For a product as chemically intricate as this one, outside verification carries extra weight. The groups that step up and publish comparative results, not just marketing blurbs, serve as force multipliers. This approach brings more labs aboard and inspires wider trust.

    A Molecule for Scientists Who Demand Results

    Complex molecules signal a new era in life sciences, where precision in chemistry carves direct paths to precision in biology. For those of us who learned science by running water through glass columns late at night, something about the careful design of N-[2-[5-Amino-1(S)-[4-(4-Pyridyl)Piperazin-1-Formyl]Pentylamino]-1(R)-(3,5-Dibromo-4-Hydroxybenzyl)-2-Oxoethyl]-4-(2-Oxo-1,2,3,4-Tetrahydroquinazolin-3-Yl)Piperidine-1-Carboxamide stands out. The world is packed full of molecules that do the job, but few invite such a combination of detailed customization and practical reliability.

    Having spent time in both basic research and applied drug discovery, I see growing value in molecules that balance synthetic sophistication with accessibility for the average bench scientist. This product fits that mold. It merges a level of modularity that helps keep the workhorse researchers interested with a level of predictability that soothes the quality assurance teams.

    What the Future Holds

    With the surge in demand for better research tools, the field will eventually shift from bulk commodity reagents to more purpose-built molecular frameworks like this one. The pipeline stretches from academic labs, through contract research organizations, straight into the regulated demands of biotech pipelines. If more scientists recognize the opportunity to swap out unstable, poorly characterized molecules for options rooted in validated chemistry and transparent sourcing, the entire process speeds up.

    The way forward includes more independent reviews, more participation from the research community, and clearer communication between manufacturer and scientist. Where skepticism runs high, those efforts will lower the barriers to adoption, and the flow of better science will follow. In the end, the real legacy of a molecule like N-[2-[5-Amino-1(S)-[4-(4-Pyridyl)Piperazin-1-Formyl]Pentylamino]-1(R)-(3,5-Dibromo-4-Hydroxybenzyl)-2-Oxoethyl]-4-(2-Oxo-1,2,3,4-Tetrahydroquinazolin-3-Yl)Piperidine-1-Carboxamide might rest not in the published studies that use it, but in the new directions it allows researchers to explore.

    As new applications appear—in high-throughput screening, in crystallography, in structure-guided drug discovery—this compound stands ready for those ready to push research further. It lends its complexity and stability to problems where easy answers rarely suffice, and in doing so, it’s likely to shape not just findings on paper but new habits and higher standards in lab practice. In a field where shortcuts almost always backfire, taking the extra step to source, vet, and apply a genuinely advanced chemical tool has become more than wise—it’s become essential.

    The real test of a product isn’t a glowing description, but the data and discoveries it enables. This molecule, with its unique chemistry, robust specifications, and clear difference from staler, blunter instruments, looks set to leave its mark well beyond the walls of any single lab or study.