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Myricitrin

    • Product Name Myricitrin
    • Alias Myricitrine
    • Einecs 208-048-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
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    Specifications

    HS Code

    398001

    Name Myricitrin
    Iupac Name 3',4',5,5',7-Pentahydroxyflavone 3-O-α-L-rhamnoside
    Molecular Formula C21H20O12
    Molecular Weight 464.38 g/mol
    Cas Number 17912-87-7
    Appearance Yellow crystalline powder
    Solubility Soluble in water and ethanol
    Melting Point 200-205°C
    Purity Usually ≥98% (HPLC)
    Source Derived from Myrica rubra and other plants
    Storage Conditions Keep in a cool, dry place, away from light
    Synonyms Myricetin 3-rhamnoside

    As an accredited Myricitrin factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Myricitrin, 1g: Supplied in an amber glass vial with a secure screw cap, labeled with product details, batch number, and safety information.
    Shipping Myricitrin is shipped in compliance with relevant chemical safety regulations, typically in secure, sealed containers to prevent contamination and degradation. Packaging ensures protection from light, moisture, and physical damage. A Material Safety Data Sheet (MSDS) accompanies the shipment, detailing handling and emergency procedures. Shipping is handled by certified carriers specializing in chemicals.
    Storage Myricitrin should be stored in a tightly sealed container, protected from light, moisture, and air. Keep it in a cool, dry place, ideally at 2–8°C (refrigerator temperature). Avoid exposure to heat and strong oxidizing agents. Proper storage ensures stability and maintains the integrity of the chemical for research or laboratory use. Always follow specific manufacturer guidelines.
    Application of Myricitrin

    Applications of Myricitrin in Industrial Manufacturing

    Myricitrin, a naturally occurring flavonoid glycoside sourced from plant raw materials, has established its industrial role primarily in the nutraceuticals, food additives, cosmetics, pharmaceutical excipients, and functional beverage sectors. As the manufacturer, we ensure consistent quality to meet precise formulation standards that support customer production operations across these specialized applications. The following sections outline key downstream scenarios, detailing compliance, formulation, process integration, and final product types.

    1. Nutraceuticals – Antioxidant Dietary Supplements

    In the dietary supplements sector, manufacturers incorporate myricitrin as a plant-based antioxidant active in tablet, capsule, and powder blends, leveraging its natural origin for clean label and plant-derived claims. Manufacturing partners require stringent traceability and batch consistency to satisfy specialized market needs, such as whole food vitamins, antioxidant health blends, and immune support formulas.

    Industry compliance standards

    • Food Chemicals Codex (FCC), current edition
    • US FDA Dietary Supplement cGMP (21 CFR Part 111)
    • European Food Safety Authority (EFSA) Novel Food Regulation (EU) 2015/2283
    • China GB 16740-2014 (Dietary Supplements) for ingredient safety

    Typical usage ratio

    • 0.05–0.2% w/w in finished supplement formulations, adjusted for antioxidant target claims and regulatory guidance on total flavonoid content

    Downstream process integration

    • Directly entered during dry blending of actives prior to granulation or tableting, ensuring uniform distribution and minimizing breakdown under heat

    Final product types

    • Antioxidant chewable tablets
    • Plant extract-based capsules
    • Immune support powdered drink mixes
    • Phytochemical-enriched gummies

    2. Functional Food Additives – Natural Coloring & Preservation

    Myricitrin sees targeted use by food manufacturers as a plant-based pigment and natural antioxidant preservative, particularly in bakery fillings, nut spreads, and high-value confectionery, where synthetic additives are restricted or discouraged. Regulatory agencies enforce rigorous traceability, purity, and concentration controls when integrating flavonoid extracts into foods marketed as natural or health-enhanced.

    Industry compliance standards

    • EU Regulation (EC) No. 1333/2008 on food additives (for colorants and antioxidants)
    • US FDA GRAS for food additive use; specific review under 21 CFR 172
    • FSSC 22000 Food Safety Management System
    • Japan Food Additives Public Standards

    Typical usage ratio

    • 50–200 mg/kg in confectionery and spreads, based on the desired antioxidative stability and visual impact

    Downstream process integration

    • Added as a fine powder or dissolved pre-mix during pre-filling of bakery mixes, cream emulsions, or before thermal setting of confectionery gels, preserving pigment stability and preventing oxidative spoilage

    Final product types

    • Nut and seed butters (almond spread, sesame paste)
    • Filled bakery pastries
    • Natural fruit gummies and jellies
    • High-antioxidant chocolate spreads

    3. Cosmetics & Personal Care – Botanical Anti-oxidant Ingredient

    The personal care industry integrates myricitrin as a botanical anti-oxidant in water-based and emulsion formulations, especially for leave-on skincare, age-defying serums, and facial masks. Downstream formulators demand plant-identical actives with full documentation and compatibility proofs for declared antioxidant activity within ISO-certified manufacturing environments.

    Industry compliance standards

    • ISO 22716 (Cosmetic GMP)
    • EU Cosmetics Regulation (EC) No. 1223/2009
    • China Cosmetic Supervision and Administration Regulation (CSAR)
    • IFRA standards for botanical extract safety

    Typical usage ratio

    • 0.01–0.1% by weight, optimized according to total extract concentration, finished product claims, and in vitro antioxidant performance

    Downstream process integration

    • Incorporated in the cool-down phase post-emulsification or directly into the aqueous phase of gels and lotions, protecting sensitive actives from heat degradation during bulk mixing

    Final product types

    • Anti-aging face serums
    • Hydration sheet masks
    • Daily moisturizers with “nature-derived” claims
    • Color-protect hair conditioner formulations

    4. Pharmaceutical Excipients – Plant-Based Stabilizer in Herbal Medicines

    Pharmaceutical manufacturers use myricitrin as a stabilizing excipient in traditional and modern herbal preparations, supporting the preservation of active components and extending shelf stability of botanical liquid or solid dosage forms. Quality assurance teams monitor its integration according to pharmacopeia standards for excipient purity and function under controlled batch operations.

    Industry compliance standards

    • Chinese Pharmacopoeia (ChP) monographs for herbal APIs and excipients
    • USP–NF General Chapters for plant-derived excipients
    • WHO GMP for Herbal Medicines
    • ICH Q7 for API excipient integration

    Typical usage ratio

    • 0.02–0.1% w/w in oral and topical phytomedicine formulations, modulated based on total active content, viscosity, and required shelf-life

    Downstream process integration

    • Mixed into core suspensions during wet granulation or homogenized into liquid extracts before sterilization and final dosing, securing antioxidant protection for unstable natural actives

    Final product types

    • Traditional Chinese medicine oral liquids
    • Herbal cough syrups
    • Softgel botanical extracts
    • Topical ointments with polyphenol content

    5. Functional Beverages – Clean Label Phytochemical Enrichment

    Beverage manufacturers integrate myricitrin to deliver natural phytonutrient content in ready-to-drink teas, health shots, and wellness tonics, focusing on brands demanding fully plant-based, antioxidant-rich ingredients. Downstream process control ensures full solubility, clarity, and flavor compatibility while maintaining regulatory compliance for shelf-stable liquid goods.

    Industry compliance standards

    • EU Regulation (EC) No. 1334/2008 on flavorings and food ingredients with flavoring properties
    • US FDA 21 CFR Part 101 (Food Labeling for beverages)
    • Codex Alimentarius General Standard for Beverages (CXS 192-1995)
    • Domestic functional beverage labeling and safety laws (e.g., Health Canada NNHPD guidelines)

    Typical usage ratio

    • 10–60 mg/L in RTD beverage base, adjusted according to declared antioxidant activity and visual clarity requirements

    Downstream process integration

    • Pre-dissolved into liquid concentrates or incorporated during low-temperature blending of beverage bases before cold/hot filling, to prevent precipitation and flavor alteration

    Final product types

    • Bottled green tea beverages
    • Functional “antioxidant boost” shots
    • Superfruit and herbal wellness drinks
    • Nutrient-fortified RTD teas
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    Certification & Compliance
    More Introduction

    Deep Dive Into Myricitrin: Experience From the Manufacturer’s End

    Why Myricitrin Matters to Chemists, Researchers, and Health Product Brands

    From the start of our chemical production journey, Myricitrin caught our attention not just for its molecular complexity, but also for the strong reaction the scientific community shows every time new data surfaces about its function and applications. As a manufacturer, my team and I spend long hours ensuring this compound matches what professionals expect. In our daily rounds, the focus on purity, particle consistency, and controlled sourcing has shaped the reputation of our Myricitrin batches. The final material speaks for itself in every NMR spectrum and purity chromatogram.

    The Backbone: Model Specifications of Our Myricitrin

    For technical teams and product managers, precision sets apart one manufacturer from the next. Our Myricitrin, typically delivered as a pale-yellow powder, has carved a spot among flavonoid glycosides for several reasons. Each production run adheres to a HPLC purity standard above 98%. Water content stays under the 2% mark. In our labs, heavy metal limits don’t cross 10 ppm. Since detection methods matter to end-users, our team continues refining sample preparation protocols to guarantee batch-to-batch consistency beyond what’s standard across the industry.

    Inside the Manufacturing Floor: Sourcing and Quality Control

    Quality cannot grow downstream from poor raw materials. Years of experience taught us to build relationships with plant growers who share protocols and transparency. The source plant Myrica cerifera—and sometimes Myrica rubra—arrives carefully dried and logged. From there, our extraction process relies on decades of plant chemistry expertise. We fine-tune solvent volumes, extraction ratios, and purification solvents. This hands-on approach reduces batch failures and upholds the lot integrity demanded by pharmaceutical formulators, supplement manufacturers, and research teams.

    Critical Differences: Myricitrin Compared to Other Flavonoids

    From a manufacturer's perspective, not all flavonoids present the same challenges or value. Quercetin, rutin, and isoquercitrin often draw quick comparisons. Myricitrin stands out with its rhamnose moiety, making it markedly more soluble in water than its aglycon cousins. That difference changes how our customers handle formulations—offering less sedimentation and easier integration into complex matrices. In our production checks, this added sugar group impacts not only solubility but stability, which matters during shipping and storage.

    How Users Leverage Our Myricitrin: From Bench to Market

    Customers reach out to us for Myricitrin with a range of applications. Antioxidant activity makes headlines, but practical uses outweigh the buzzwords. In food and supplement product labs, formulation scientists introduce Myricitrin to stabilize sensitive ingredients or reduce free radical load in plant-based blends. Cosmetic manufacturers request our finer grades for integration into botanical creams where water compatibility and subtle yellow color matter. On the biomedical front, research teams document Myricitrin’s influence in enzyme inhibition studies related to inflammation, chronic oxidative stress, or neurodegenerative pathways.

    For some clients, thermal stability stands at the core. Our in-house accelerated stability studies show Myricitrin outperforms unmodified flavonoids under high-humidity and elevated temperature tests, thanks to its glycosylated structure. The shelf life, documented over years of side-by-side comparisons, lessens waste and logistic headaches downstream for partners with global distribution channels.

    Sustainability and Transparency: What Raw Material Sourcing Looks Like

    Trust grows over years of consistent delivery. As manufacturers, we recognized early on that transparency at every sourcing stage helps our clients meet compliance standards in both Europe and North America. Buying crude extracts without knowledge of the growing or drying process produces uneven product. For accountability, we pull plant origin certificates and random test for pesticide residues even before solvent extraction begins. The value comes forward in clean final chromatographic profiles and lack of off-notes in end formulations.

    Sustainability also brings a long-game perspective. Wild harvesting presents benefits and pitfalls: wild plants sometimes offer stronger active profiles, but sustainable collection practices must be monitored closely to prevent overharvesting. With Myricitrin, we frequently prefer cultivated sources grown on contract, which allows traceability from seed to shipment.

    Troubleshooting Challenges in Industrial-Scale Myricitrin Production

    Scaling lab processes into ton-scale production exposes weaknesses in many supply chains. Over the years, we found that extraction solvent choice and filtration techniques make or break the final yield and purity. Solvent recovery methods cut costs and environmental impact but demand strict controls, so we reinvest in closed-loop systems and real-time monitoring tools to keep solvents clean and batches uniform.

    Crystallization steps require close operator supervision: temperature ramps and slow solvent removal prevent oils and impure residues from contaminating crystals. Several competitors market crude powders with higher apparent yield but much lower purity or inconsistent color. Feedback from senior technical advisors at our partner research institutes influenced our choice to refine further, with mother liquor recycling and multiple crystallizations when necessary. That decision costs more per kilo, but our repeat customers cite easier downstream handling and compliance with international pharmacopoeia benchmarks as clear benefits.

    Compliance, Certificates, and Traceability: Meeting Industry Demands

    Documentation and compliance move beyond paper. Clients request not only standard Certificates of Analysis, but also data sets tied to individual lots. We transitioned years ago to electronic record-keeping, allowing researchers and regulatory officers immediate access to batch histories. Food and supplement clients require allergen and contamination screenings, so our QC labs conduct targeted tests for heavy metals, pesticide residues, and common microbial contaminants.

    For each shipment, our lot traceability runs from harvest date through final packing. This system sped up our response during an impurity scare in another supplier’s supply chain; clients shifted orders to us after losing trust in anonymous-sourced material. Confidence comes from this visible process, not just brand loyalty.

    Customer Experiences: Feedback From the Field

    Open feedback cycles drive our product improvement. A supplement manufacturer once reported dispersibility issues after switching blending agents. Instead of blaming user error, our team visited their production site and ran joint trials. Adjustments to our final drying method delivered a finer, less lump-prone grade within two production runs. The ultimate result: a more stable capsule product and fewer formulation complaints reported downstream.

    Another research partner shared concerns about off-flavors affecting a food additive line. Back in our facility, sensory panels and GC-MS screening linked the issue to a trace compound formed during overlong solvent exposure. We worked side-by-side with their team, adjusted our extraction time, and solved the flavor issue at the root. This kind of collaborative troubleshooting marks the difference between producing a commodity and becoming a long-term strategic supplier.

    Innovating for Future Applications

    Over time, the demands put on Myricitrin have shifted. Early on, antioxidant and anti-inflammatory functions dominated the literature, but our clients now explore uses in advanced material science and as lead compounds in pharmaceutical development. Meeting these technical requirements means innovating in purification—not just extracting pure Myricitrin, but also separating isomeric forms and identifying possible synergistic partners for combination studies.

    In our pilot plant, supercritical CO2 extraction delivers cleaner fractions with reduced solvent residues, opening new potential in clinical development programs. Analytical method development no longer stops at HPLC: we now supply reference standards for LC-MS/MS and NMR, helping clients meet tightening regulatory scrutiny on both ingredient identity and traceability. Our R&D team puts significant effort behind making new grades ready for customers looking beyond traditional supplement or food usage.

    Continuous Improvement: Rethinking Production for Tomorrow’s Demands

    Over time, standards in chemical manufacturing continue advancing. Staying ahead requires not just up-to-date equipment, but also a culture of continuous learning and training. Our operators attend regular in-house and external courses to keep up with shifting regulatory demands and advances in green chemistry. Upgrading to more automated filtration and in-line analysis systems reduced batch variation and allowed quicker response to in-process changes.

    Customer-focused metrics steer every project. If food technologists report problems with mouthfeel or researchers bring up solubility issues in cell media, our R&D group takes it as a challenge. Past successes often come from breaking with tradition—sometimes by swapping legacy filtration aids, sometimes by combining extracts with stabilizing partners. Our day-to-day data sets track each change, building a knowledge bank that accelerates future improvement.

    Addressing Limitations: Real Challenges, Real Solutions

    No process achieves perfection. Myricitrin tends to degrade under strong acidic or alkaline conditions, which restricts the choice of excipients and packaging. Pharmaceutical developers sometimes want to combine Myricitrin with unstable actives or embed it in harsh pH environments. Here, our technical team runs stress tests on proposed blends, sometimes suggesting capsule filling over direct compression, or offering encapsulation partners skilled in spray-dried or liposomal formats.

    Shipping logistics also force creative thinking. In humid tropical climates, standard polyethylene liners alone won’t hold back caking or discoloration. After some failed transport tests and customer reports, we switched to double-layer barrier bags and ran climate chamber trials, ensuring the Myricitrin reaches international partners in the same condition as it left our dock. Learning from missteps opened doorways to more robust packaging and higher professional standards.

    Supporting Documentation for the Analytical Community

    Academic and commercial research teams alike request full transparency in analytical data. Alongside Certificates of Analysis, we provide characterization data: proton and carbon NMR, mass spectra, IR data, and chromatograms for each batch. Technical dossiers with toxicity and stability data lighten the regulatory workload for clients registering new nutraceuticals or seeking pharma approvals.

    For new customers or complex projects, our staff chemists support analytical method transfer and troubleshooting, providing insight drawn from hundreds of successful ramps. The advantage isn’t just knowing how to make a high-purity product, but also speeding up commercialization and supporting peer-reviewed publication.

    Trust Built By People: The Role of the Team in Myricitrin Production

    Machines and automation make scale possible, but people run the process and notice trends before data can. Our shift supervisors bring decades of hands-on experience, fine-tuning processes during extreme weather or raw material variability. This lived knowledge prevents costly mistakes: a subtle color or texture change often reveals a hidden issue with extraction temperature or solvent saturation. Regular cross-department meetings help us flag disruptions, share learnings, and build resilience into future production runs.

    Hiring for attitude and skill, then investing in ongoing education, pays off. Teams who understand the why behind protocols adapt faster when incoming material changes. We push everyone across operations, quality, and logistics to share observations and propose process tweaks. This agility sets real manufacturers apart from traders or repackers, who lack the lab and plant data to recognize, diagnose, and solve subtle quality challenges.

    Staying Ready for Future Regulation and Market Demand

    Regulators show growing interest in traceability, safety, and full-chain documentation. We see audits not as obstacles, but as reality checks on our internal systems. Early adopters of block-chain based records within our company have found audits run smoother and customer questions resolve faster. In meetings with large food, supplement, and pharma buyers, real-time data access has helped retain long-term contracts and cemented confidence in our production.

    Markets shift. Subject trends in health and wellness change regularly, so Myricitrin’s main applications evolve from anti-inflammatory uses toward metabolic, cognitive, or gut health. Staying close to both scientific literature and user needs keeps our R&D pipeline healthy. Consistent input from external researchers, end users, and even critical competitors informs us how to tweak production or invest in next-generation purification methods for years ahead.

    Final Thoughts: Why Source Myricitrin From An Experienced Manufacturer

    Production of Myricitrin at scale marries scientific rigor with hands-on expertise. Whether researchers look for batch consistency, supplement brands focus on clean label compliance, or pharma developers prioritize traceability, the trust built through consistent delivery, open communication, and technical know-how proves essential. As the scope of application broadens, the decisions made daily by our team—from raw material selection down through purification and shipment—shape not only the reliability but also the future possibilities of Myricitrin for our partners around the world.