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Monosodium Fumarate

    • Product Name Monosodium Fumarate
    • Alias Fumaric acid, monosodium salt
    • Einecs 244-334-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry sales7@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    813719

    Chemicalname Monosodium Fumarate
    Chemicalformula C4H3NaO4
    Molarmass 158.05 g/mol
    Appearance White crystalline powder
    Solubilityinwater Soluble
    Casnumber 544-17-2
    Meltingpoint 195 °C (decomposes)
    Phvalue Approximately 2.5-3.5 (1% solution)
    Odor Odorless
    Synonyms Sodium fumarate
    Stability Stable under normal conditions
    Taste Slightly acidic

    As an accredited Monosodium Fumarate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Monosodium Fumarate, 500g: White, sealed HDPE bottle with tamper-evident cap, labeled with chemical details, hazard warnings, and batch information.
    Shipping Monosodium fumarate should be shipped in tightly sealed containers, protected from moisture and incompatible substances. It is typically transported as a solid in durable packaging, labeled according to local and international regulations. Handle with gloves and safety equipment, and store in a cool, dry, well-ventilated area during transit to prevent degradation.
    Storage Monosodium fumarate should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from moisture, heat, and direct sunlight. Avoid storage near oxidizing agents or strong acids. Ensure proper labeling and avoid contact with incompatible substances. Use secondary containment to prevent spills and keep the storage area clean and free from combustible materials.
    Application of Monosodium Fumarate

    Applications of Monosodium Fumarate in Industrial Manufacturing

    As a direct manufacturer, we supply monosodium fumarate to various downstream sectors where its chemical properties bring technical value. Below, we outline real-world application scenarios, covering compliance, formulation practice, typical dosage, downstream configuration, and resulting end-products.

    1. Acidulant in Beverage and Food Processing

    Food industry manufacturers use monosodium fumarate as a controlled acidulant and pH regulator in functional beverages, processed meats, bakery fillings, and low-sodium food matrixes. Its acidification impact extends shelf life and livens flavor profile, while its sodium content offers precise electrolyte management in reduced-salt or specialty dietary lines. Producers select this ingredient for its heat stability and delayed acid release, especially in high-temperature filling or baking stages, compared to free fumaric acid.

    Industry compliance standards

    • Codex Alimentarius (INS 297, maximum levels per final food type)
    • FDA 21 CFR §172.350 (Fumaric acid and its sodium salts in food)
    • EU Regulation No 1333/2008 (listed authorized food additives, E297)
    • China GB 2760-2024 (National Food Safety Standard - Standards for Use of Food Additives)

    Typical usage ratio

    • 0.05% – 0.30% by weight in finished food; precise ratio based on the target pH, buffer system, and formulation constraints for sodium intake (see capped usage in infant and health foods)

    Downstream process integration

    • Dosed in batching tanks after dissolved solids or before heat/aseptic steps
    • In baked goods, blended with dry premix before hydration to control acid release profile
    • Used in meat marinades as a pH buffer during curing stage
    • Added during final blending of powdered drink mixes to enhance dissolution and flavor stability

    Final product types

    • Isotonic beverages and sports drinks
    • Processed meats including sausages, bacon alternatives, jerky
    • Layered cake fillings, jams, fruit spreads
    • Instant beverage powders

    2. Intermediate in Pharmaceutical Synthesis

    Monosodium fumarate functions as a building block in the synthesis of active pharmaceutical ingredients (APIs), including sodium fumarate injectable solutions and fumarate-based salts for controlled drug release. Its use ensures precise sodium and fumarate ion stoichiometry in forming prodrugs and complex drugs. Production facilities rely on its high-purity, low heavy metal specification, and traceable GMP-compliant supply for sensitive API processes where consistency and contamination control are critical.

    Industry compliance standards

    • Current Good Manufacturing Practice (cGMP, ICH Q7)
    • USP-NF (United States Pharmacopeia, monographs for fumarate derivatives)
    • European Pharmacopoeia (Ph. Eur.) requirements for excipient use
    • China Pharmacopoeia (ChP) specifications for pharmaceutical excipients

    Typical usage ratio

    • Measured as stoichiometric equivalents in salt formation; typically in 1:1 or adjusted molar ratio with API or co-formulation agent based on pharmaceutical formulation process

    Downstream process integration

    • Charged with APIs during salt-forming crystallization steps
    • Dissolved in water-for-injection for sterile injectable solution preparation
    • Incorporated in granulation or direct compaction blending for oral dosage forms
    • Applied in inline salt exchange for prodrug synthesis or ion modulation steps

    Final product types

    • Extended-release tablets containing fumarate-based active compounds
    • Injectable solutions (e.g., sodium fumarate injection for specific therapies)
    • Fumarate salt forms of APIs for anti-inflammatory, immunomodulatory, or anti-viral drugs
    • Clinical trial materials requiring defined fumarate sources

    3. Additive in Livestock and Aquaculture Feed

    Feed producers employ monosodium fumarate as an acidifying and buffering agent to regulate gut health, manage rumen metabolic balance, and mitigate methane emissions in animal production. Its use permits targeted pH modulation and supports beneficial microflora, improving nutrient absorption in high-density rearing environments. The sodium and fumarate ions contribute to animal electrolyte balance and oxidative stress management. Feed integrators value its stable handling profile and absence of undesirable by-products compared to alternative organic acids.

    Industry compliance standards

    • EU Catalogue of Feed Additives Regulation (EC) No 1831/2003
    • AAFCO (Association of American Feed Control Officials) – Fumaric acid, sodium salts
    • China Feed Additive Standards (GB/T 1886.43-2021, GB13078)
    • Good Manufacturing Practice for Premix Feed (FDA CFR 21 part 225)

    Typical usage ratio

    • 0.10% – 1.00% of total feed, adjusted based on target animal species, feed type (starter, grower, finisher), and existing dietary acid load; lower application for layer poultry, higher ratios for ruminants to optimize pH

    Downstream process integration

    • Pre-mixed with dry microingredient blends before pelleting or extrusion
    • Added to liquid feed supplements, with complete dispersion during mixing
    • Integrated in post-extrusion coatings to achieve functional release in the digestive tract
    • Used in customized ruminant or aquafeed blends for methane reduction or anti-bloat premixes

    Final product types

    • Pelleted compound feeds for swine, broilers, and dairy cattle
    • Specialty feed pre-mixes for aquaculture and finfish rearing
    • Mineral-vitamin concentrates with fumarate as stabilizer
    • Ruminant methane inhibitor blocks and feed additives

    4. Ingredient in Laundry and Cleaning Product Formulations

    Home care and institutional cleaning product manufacturers use monosodium fumarate as a chelating and buffering agent in powdered and liquid detergents, water softeners, and specialty cleaners. Its functionality supports control of water hardness, enhances the cleaning ability of surfactant blends, and helps maintain product pH stability over shelf life. The salt form offers lower corrosivity in alkaline systems than mineral acids. Companies incorporate it to address local regulatory needs for low-phosphate or phosphate-free cleaning products, leveraging its high degradability as an environmental benefit.

    Industry compliance standards

    • REACH (EC 1907/2006) registration for chelating agents
    • Detergent Regulation (EC) No 648/2004 (for environmental and labeling requirements)
    • US EPA Safer Choice certification criteria
    • China Detergent Standard GB/T 9985, 2021

    Typical usage ratio

    • 0.2% – 1.2% in the total detergent formulation; level tuned for target water hardness, final pH, and compatibility with other ingredients; increased ratios in hard water markets or phosphate-substitution systems

    Downstream process integration

    • Dry blended during the powder detergent compounding before granulation
    • Premixed into aqueous phase in liquid detergent production, ensuring complete dissolution before addition of surfactants
    • Incorporation into dishwasher tablet compacts to control alkalinity spike and prevent scale build-up
    • Used in water softening granules as an auxiliary to sodium citrate or other chelators

    Final product types

    • Automatic dishwashing powders and tabs
    • Heavy-duty laundry detergents (powdered and liquid)
    • Water softener blends for household and commercial use
    • Multi-purpose cleaning powders for institutional hygiene

    5. Crosslinking Agent in Unsaturated Polyester and Resin Systems

    Chemical and composite materials manufacturers use monosodium fumarate as a controlled crosslinking and curing auxiliary in unsaturated polyester resin (UPR) and thermosetting polymer systems. Its sodium salt form allows for precise adjustment of resin acidity and improved dispersion in aqueous-phase reactive formulations. The result is controlled polymer network formation, minimizing residual acid and fostering enhanced color stability in end-use applications such as corrosion-resistant tanks, pipes, and molded composites. The chemical’s high purity aligns with the technical demands of advanced composite manufacturing.

    Industry compliance standards

    • ASTM D638-22 (Standard Test Method for Tensile Properties of Plastics) for molded resin samples
    • ISO 9001:2015 Quality Management for resin production
    • REACH (EC 1907/2006) compliance for resin chemicals
    • RoHS Directive (2011/65/EU) for electrical/electronics resins with restricted substances

    Typical usage ratio

    • 0.2% – 1.0% w/w based on total resin solids; ratio adjusted by target polymer-acid value, ambient temperature, and mechanical property requirements of the composite

    Downstream process integration

    • Charged in initial resin kettle with unsaturated diacids for neutralization
    • Added post-polymerization in water-based resin dispersions as a pH adjuster and mild crosslinker
    • Blended with fillers and pigments in bulk mold compound production before pressing or extrusion
    • Used as a curing regulator in composite prepreg materials for high-performance parts

    Final product types

    • Glass fiber reinforced pipes and tanks
    • Molded UPR-based auto or marine parts
    • Corrosion-resistant industrial paneling
    • Electrical composite insulators
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    Certification & Compliance
    More Introduction

    Monosodium Fumarate: Manufacturing Reliability and Functional Excellence

    Building Value Through Experience and Precision

    Producing Monosodium Fumarate goes well beyond batch controls and outcome tracking. This salt of fumaric acid reflects careful chemistry, clean operations, and resilient logistics. From sourcing high-purity starting materials to achieving the right balance in crystallization, each step brings its own hands-on learning curve. We don’t recommend Monosodium Fumarate because it trends on paper; our conviction grew in full-scale runs and real-world problem-solving. Those who have loaded reactors, adjusted pH, or run purification know that each lot draws on daily lessons from the prior. We meet customers not just at the shipping dock, but through the transparency and care of strong, repeatable process.

    Understanding Monosodium Fumarate’s Distinctive Role

    Raw fumaric acid sits on many chemical operators’ shelves, but pure Monosodium Fumarate marks a shift in both molecular behavior and application scope. Sporting a single sodium counterion, it carries unique water solubility patterns and a reserved acidity profile. This translates to controlled reactivity and gentle handling during downstream formulation, be it for food additives, pharma excipients, or specialty polymers. Organic chemists seeking predictable ionic conversion favor monosodium versions for their intermediate character—less aggressive than dibasic salts, but more soluble and manageable than the stark parent acid. In our reactors, we monitor both stoichiometry and grain size, knowing minor slips can drive unwanted agglomeration or leave unreacted residues. Continuous feedback between manufacturing staff and development chemists sharpens this control.

    Model, Purity, and Specification Practices

    On our line, Monosodium Fumarate carries its own identity; we don’t treat it as a byproduct of fumaryl processes or a sideline to more popular salts. Consistency in grade matters more than batch sticker or catalog code. Routine analyses include sodium assay, moisture content, and minimal sulfate levels, using in-house validated methods. Aiming for a tightly specified purity—often above 99%—lets downstream partners lean on predictable dosing. Color, free-flowing nature, and just-perceptible odor variations can come up, especially when scaling up or running late in a campaign. Experienced teams quickly identify and reroute such lots, knowing any deviation signals something upstream worth fixing. Regular engagement with independent labs supplies external verification, not just compliance checkboxes.

    Direct Applications Rooted in Practical Knowledge

    Monosodium Fumarate enters production lines where balance matters. Bakeries use it for flavor smoothness and dough pH adjustment, trading harsh acidulants for steady sour profiles. Pharmaceutical technologists rely on it to help tablets dissolve right—the sodium ion fosters quick hydration, supporting more efficient and complete drug release. Sometimes, our own engineers swap fumaric acid for its monosodium form to temper reaction rates in esterification, especially in temperature-sensitive runs. No two sectors use it with quite the same philosophy, but each returns to the core feature: reliable, moderate reactivity with easy downstream removal.

    In food tech, for instance, Monosodium Fumarate tackles a classic challenge—separating acid taste from unpleasant aftereffects. Unlike citric or tartaric acid, it doesn’t flood recipes with late-onset bitterness or excessive astringency. The sodium aspect modestly bumps up functional saltiness, allowing formulators to reduce other mineral salts. Controlled particle sizing ensures that it disperses at the right pace in dough or beverage mixes, sidestepping localized clumping. Chefs and process engineers share feedback with our technical teams, asking for minor tweaks in granule size or drying profile to synchronize with existing equipment. Those conversations steer not only manufacturing batch design but sometimes even reactor upgrades.

    Water soluble, with smoother dissolution than its dibasic relative, Monosodium Fumarate also finds favor in sensitive tablets and granules. Pharmacists voice concerns about excipient-driven instability; our process leaders respond by tightening process water sources and reviewing environmental controls. Formulators expect a clean, non-reactive excipient that won’t trigger unwanted hydrolysis or oxidize actives. We continually measure not only absolute purity but also residual oxidants, maintaining conditions where product color and odor remain unchanged through storage.

    Comparing Monosodium Fumarate with Kindred Compounds

    We field frequent questions about differences between Monosodium Fumarate, plain fumaric acid, and disodium fumarate. These aren’t interchangeable. Fumaric acid, notable for low cost and easy supply, brings tough solubility and sharp taste. Monosodium Fumarate’s partial neutralization soothes both of those edges, yielding a salt that blends, dissolves, and regulates pH far better in aqueous systems. Its sodium load sits halfway between none (fumaric) and full substitution (disodium), offering flavor and functionality splits that matter for each recipe or compounding step.

    Compared to disodium fumarate, our product carries less sodium per mole—crucial for applications like food, where sodium content can’t always flex without consequences. In pharmaceutical tablets, formulating with Monosodium Fumarate grants more room for builders, sweeteners, or actives before sodium limits or reactivity issues surface. Disodium fumarate, by contrast, dissolves even more rapidly, but pushes both reactivity and sodium content higher than some processes tolerate.

    Monosodium Fumarate separates itself most clearly in recipes targeting smooth onset and long-lasting pH stability. It doesn’t crash out or cake as easily as some other salts when handled with proper drying and sealing. The intermediate sodium level smooths out both acid and base behaviors, making it a buffer and flavor modulator, not simply an acidifier or bulking agent. These balanced features drive demand across disparate markets—a fact we experience through orders from both global baking firms and targeted pharma startups.

    Manufacturing Discipline: From Theory to Factory Floor

    Running a batch of Monosodium Fumarate demands equal parts trained intuition and textbook knowledge. Exotherms during neutralization form only a small part of the challenge. Operators track the changing viscosity of the reaction mixture, noting timepoints where crystal agglomeration might threaten filterability. Reaction rate control—achieved by real-time temperature adjustment and stoichiometry checks—pushes consistency in yield and prevents unwanted side-product formation. Several runs might be necessary to map an optimum cycle.

    On the purification front, every chemist faces their share of scale-up surprises. Fumaric acid and its sodium salts present filtration nuances, especially as seasonal humidity changes or upstream supplier variability sneak in. Batch drying controls—temperature, pressure, and airflow—all show their full effect on downstream product handling. Too slow, and residual moisture fosters caking; too fast, and the product hardens unevenly. We found that regular, small tweaks in drying profiles, rather than big setpoint swings, deliver predictable texture and storage results. Cleanroom practices, from filter bag changes to operator garments, play just as crucial a role in keeping our final material close to spec as the original reactor design.

    Practical Storage Tips Learned on the Job

    Official guidance calls for dry, cool-storage under sealed conditions. Years on the floor have shown that double-bagged high-barrier liners inside plastic drums greatly reduce caking and external odor pickup. Workers glance past standard moisture indicators; instead, they judge product health by running a hand through the powder, testing flow, or even crushing a bit under the heel of a glove. A whiff of sourness or lumps during drum opening prompts tracing through both in-plant handling and truck transit records. Feedback loops like these mean offbeat customer complaints—say, a batch hardening in transit—transform quickly into action. Closing those loops requires both formal checks and that lived-in plant experience where one sniff or handful often reveals more than readouts ever could.

    Customers who adopt similar practices—sealed drums, controlled rooms, minimal air exposure—see nearly zero shelf-life incidents. We’ve shared these details in site visits, watching new partners transition from product issues to stable, trouble-free handling just by focusing on these unsung basics.

    Continuous Improvement Based on Real-World Performance

    Feedback, both positive and sharply critical, drives steady improvements to our Monosodium Fumarate process. We document more than just the last test report or certification; plant logbooks, “walk-the-line” inspection records, and maintenance histories all become open records accessible to technical partners. When unusual results turn up—off-color, slow dissolving, grains deviating from spec—traceability kicks in. Our operators, trained to spot shifts in reactor noise or feel, escalate anomalies fast. These daily habits close gaps that remote or third-party suppliers might miss.

    Regular technical reviews, held in person or by video, let both our staff and customers review not only the product numbers, but also the stories behind them. Sometimes a “superior” number can mask a new handling issue. Each improvement round folds customer stories into R&D tests, confirming real use trumps lab-only findings. Where direct measurement falls short, we lean on both internal wisdom and external experts, sometimes inviting customer-site observation to see product action under real constraints. This collaborative environment continually tightens every turn of production, packaging, and shipping.

    Meeting Health and Safety Protocols Without Compromising Efficiency

    Laboratory-scale safety protocols transfer only so far to large-scale Monosodium Fumarate handling. Operators suit up, but also know the thousand-yard cues—a sheen on the floor meaning a slipped drum, the scent of solvent drift after a power hiccup. Standard personal protective equipment aligns with general food and pharma practices. Gloves, dust masks, and eyewear come standard, but we find education—covering both accident scenarios and simple muscle memory—offers more real-world protection than posters on the wall. Each new hire spends time shadowing an experienced operator, picking up not just the “what” but the “why” of every safety measure. Those habits lower station errors, from mislabeling to unplanned cross-contact.

    Our plant’s air monitoring ties into particulate counters and chemical exposure sensors. Expanded cleaning protocols, sparked by both regulation and real-world partnership visits, keep cross-contamination in check. We log every cleaning event, building an archive that tracks root causes behind faulty lots or near-misses. Plant tours for customers offer transparency into this process—open doors to the production suite and storage, guided by supervisors willing to show every corner. These hands-on checks close the loop between what’s promised and what’s delivered.

    Addressing Environmental Stewardship Through Direct Action

    Waste reduction begins in the design of a Monosodium Fumarate batch. Unreacted acid and salt streams pose not simply disposal headaches but areas where tight control pays dividends. In our plant, we run side audits on every campaign, aiming to reduce off-spec side streams that would otherwise need neutralizing and landfilling. By tracing recurring deviations to root causes—often subtle issues like tank mixing efficiency or filtration blinding—we’ve reduced byproducts reaching the effluent line.

    Water stewardship gets similar focus. Each stage, from reaction charging to final washing and drying, is metered and reported in real time. Maintenance teams check for drips and faulty valves by hand; even minor leaks signal process inefficiencies and waste. Partnerships with municipality authorities help us reclaim treated water from side streams, closing the loop without sending byproducts downstream.

    Packaging, once overlooked, became a major focus as sustainability pressure increased. We’ve shifted much of our drum stock to materials recovered from our own supply chain and customers, working out reuse protocols that balance safety and waste goals. Customers returning empties or drums help our circularity program. Each one kept out of landfill proves the approach works, especially as cost savings work both for us and downstream partners.

    Enhancing Supply Chain Reliability Through Direct Communication

    Supplying Monosodium Fumarate reliably means actively managing each risk, not just passing along freight bills. Weather disruptions draw quick responses—logistics reroutes and stockpiling for critical users start at the first warning. Our production aligns with real demand trends, forecasted not just by last year’s orders, but from open conversations with manufacturers, formulators, and shippers. Inventory staff and manufacturing planners conduct daily calls, sharing updates from both plant floors and customer QC labs.

    Problems arise—port congestion, carrier mix-ups, changing regulatory labels—and get solved by people, not policy. Each supply hiccup reveals new bottlenecks: missed transport pickups, shifting lead times, or regulatory curveballs. Each solution grows from direct stakeholder talks, not silent correction notices or finger-pointing emails. Transparency—applied daily at the loading dock and in customer meetings—keeps the chain strong, even under strain. In some regions, partnering with more than one forwarder or shipping group added a layer of resilience that pays back during disruptions.

    Direct Support Fosters Long-Term Partnerships

    Expertise on Monosodium Fumarate doesn’t end once the bag ships out. We follow projects through trial, ramp-up, and ongoing production, staying plugged into engineering and formulation teams via direct phone calls and impromptu site visits. Problems—dissolution quirks, batch caking, or unplanned downtime—often become new case studies, feeding back fixes that benefit future lots. Our customers know not every issue draws out a new spec sheet; sometimes, changes mean only an adjustment in drying, a simple tweak to granule size, or a double-check of reactor pH protocol.

    Education bridges plenty of gaps. We’ve hosted workshops where plant operators, bakers, and formulators gather to handle the product, compare tricks, and note subtle cues in handling. Knowledge takes root best not through reports, but by working together through real scenarios—a batch gone sticky, a blend refusing to dissolve, a shipment exposed to humidity. These gatherings spark connections, allowing best practices to flow backwards into our own production systems.

    Integrating digital traceability brought new confidence to users who once felt blind after a delivery. QR-coded batches, detailed run histories, and open access to production notes all let partners validate what arrives against what’s documented in trials. These low-friction access points add a twin layer of quality control—one engineered in the lab, the other maintained by our process realities.

    Working With Customers to Shape Tomorrow’s Monosodium Fumarate

    Those handling Monosodium Fumarate in the field offer more than market demand—they spot features and limitations long before any process engineer. A food processor’s insight about improved flowability led us to re-examine drying techniques; a tablet manufacturer describing subtle changes in dissolution speeds spurred new discussions on water control and particle shape. These findings go directly to shift leads and R&D.

    Customers who push boundaries—modifying blends, inventing layered confectionaries, or reformulating vitamin tablets—often chart the next technical advance. We meet that challenge with investment—better sensors, new drying setups, and upgraded in-process analytics. Hand-in-hand trials, where both our technical crew and partner operators log every result, reveal what works beyond the scope of a single plant’s bench test. From those alliances, breakthrough improvements seed updates that stick, not just in one market, but across every sector hunting for gentle, reliable acidic regulation.

    Experience makes the difference in Monosodium Fumarate manufacturing. Operators who recognize the feel of the final blend, chemists who can spot yield swings by the look of a filter cake, and engineers balancing efficiency against downstream effects—all cement our commitment to making this product a foundational, dependable choice. We view every partner not as a transaction, but as a co-creator. Each advantage and new idea, proven in labs, workshops, and plant floors, becomes a resource, strengthening both our product and every industry that puts Monosodium Fumarate to practical use.