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Monoolein

    • Product Name Monoolein
    • Alias Glyceryl monooleate
    • Einecs 246-245-6
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    177898

    Cas Number 111-03-5
    Molecular Formula C21H40O4
    Molar Mass 356.54 g/mol
    Appearance White to off-white waxy solid
    Melting Point 34-38°C
    Solubility In Water Insoluble
    Solubility In Ethanol Soluble
    Flash Point 160°C
    Iupac Name 2,3-dihydroxypropyl (Z)-octadec-9-enoate
    Synonyms Glyceryl monooleate, GMO, 1-monoolein
    Density 0.94 g/cm³
    Odor Fatty, mild
    Stability Stable under recommended storage conditions

    As an accredited Monoolein factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Monoolein is packaged in a sealed 500g amber glass bottle with a tamper-evident cap, clearly labeled with product details.
    Shipping Monoolein is typically shipped in tightly sealed containers, protected from moisture, air, and extreme temperatures to maintain stability and purity. Packaging usually involves food-grade drums or bottles, compliant with safety regulations for non-hazardous chemicals. Proper labeling and documentation accompany each shipment to ensure safe and efficient handling during transport.
    Storage Monoolein should be stored in a tightly closed container, away from light, moisture, and incompatible substances such as strong oxidizing agents. It should be kept in a cool, dry, and well-ventilated area, ideally at room temperature (15–25°C). Ensure the storage area is clearly labeled and complies with local regulations for chemical storage.
    Application of Monoolein

    Applications of Monoolein in Industrial Manufacturing

    Monoolein, a glycerol monoester of oleic acid, serves as a high-functionality non-ionic surfactant and structuring agent in multiple manufacturing chains. Our direct involvement as an upstream chemical manufacturer ensures thorough understanding of industrial processing and compliance, supporting customers in diverse downstream applications. Below are the main industrial sectors using monoolein as a key raw material, with a focus on compliance, formulation, process usage, and final products.

    1. Food Emulsifiers and Texture Modifiers

    Food processing plants use monoolein as an emulsifier and emulsifying base to stabilize water-in-oil or oil-in-water systems, enhance structural texture, and control crystal morphology in end products such as margarine, non-dairy creams, and specialty fat-based spreads. Quality control is critical, as is adherence to food safety and purity guidelines across markets.

    Industry compliance standards

    • FAO/WHO JECFA Food Additive Specifications (INS 471)
    • U.S. FDA 21 CFR 184.1323 (Generally Recognized As Safe for mono- and diglycerides)
    • EU Regulation (EC) No 1333/2008 on food additives
    • China GB 2760 Food Safety National Standard—Food Additive Use

    Typical usage ratio

    • 0.2%–2.0% by weight of finished product, optimizing stability and mouthfeel based on fat phase and desired emulsion type

    Downstream process integration

    • Oil phase pre-mixing at 60–75°C before homogenization or direct addition into molten fat fractions for batch or continuous processes

    Final product types

    • Margarine and shortening
    • Whipped toppings and non-dairy creamers
    • Processed cheese spreads
    • Filled chocolates and fat-based confectionery

    2. Pharmaceutical Controlled Release Formulations

    In pharmaceutical manufacturing, monoolein creates lyotropic liquid crystalline systems for controlled drug release in oral, topical, and implantable dosage forms. Its amphiphilic structure enables self-assembling matrices that provide targeted, sustained delivery of poorly soluble actives, helping formulators address bioavailability and regulatory requirements.

    Industry compliance standards

    • USP-NF Monograph for Mono- and Diglycerides
    • Ph. Eur. 2.4.22 Directives for excipients
    • ICH Q7 GMP guidelines for APIs and excipients
    • 21 CFR 174, 175 for indirect food/drug additive status, where applicable

    Typical usage ratio

    • 5%–40% in lipid-based matrices, adjusted based on active drug solubility, release profile, and delivery route requirements

    Downstream process integration

    • Thermal melting and co-melting with solid or semi-solid lipids for pre-concentrate preparation, followed by high-shear mixing and, if needed, subsequent lyophilization or encapsulation processes

    Final product types

    • Oral sustained-release capsules and tablets
    • Topical gels and creams with liquid crystal structure
    • Long-acting drug implants
    • Lipid nanocarriers and nanoemulsions for poorly soluble APIs

    3. Cosmetic Creams and Dermatological Base Systems

    Cosmetic and personal care manufacturers utilize monoolein as a non-ionic surfactant and moisturizing structurant, forming lamellar or cubic gel networks that stabilize water-oil dispersions and act as a penetration enhancer. This improves performance and shelf-life of skin creams, balms, and medicated formulations, supporting robust sensorial and therapeutic results.

    Industry compliance standards

    • EU Cosmetic Regulation EC 1223/2009
    • U.S. FDA Voluntary Cosmetic Registration Program (VCRP)
    • ASEAN Cosmetic Directive
    • ISO 22716 (Cosmetic GMP Standard)

    Typical usage ratio

    • 1%–6% depending on desired viscosity, gel structure, and active loading compatibility

    Downstream process integration

    • Hot emulsification through oil phase blending at 65–80°C, followed by high-shear or paddle mixing, then cooled to set structure and avoid phase separation

    Final product types

    • Moisturizing and medicated creams
    • Body butters and balms
    • Sunscreens and after-sun gels
    • Transdermal patch matrices

    4. Industrial Lubricants and Metalworking Fluids

    Manufacturers of industrial lubricants and cutting fluids apply monoolein as a biodegradable, anti-wear additive and lubricity enhancer. It provides stable, low-toxicity emulsification, improves metal surface performance, and supports environmental compliance, particularly for rapidly biodegradable or food-grade lubricants.

    Industry compliance standards

    • OECD 301 Biodegradability Tests
    • NSF H1 (for lubricants with incidental food contact)
    • ISO 12925-1 (Lubricants, industrial oils and related products)
    • REACH Regulation (EC) No 1907/2006—Safety Data Sheet and environmental disclosure

    Typical usage ratio

    • 0.5%–4% by total formulation mass; adjusted depending on base oil blend and anti-corrosion system requirements

    Downstream process integration

    • Direct addition during base oil compounding, or emulsifier phase blending at controlled temperature before package homogenization

    Final product types

    • Biodegradable hydraulic fluids
    • Metalworking emulsions and coolants
    • Chain lubricants for food plant machinery
    • Grease thickeners for specialty lubricants

    5. Plasticizer and Additive in Polymer Film Manufacture

    The polymer film and packaging sector incorporates monoolein as an internal plasticizer and slip agent, enhancing flexibility, mechanical properties, and antistatic performance for polyvinyl chloride (PVC), cellulose derivatives, and thermoplastic starch films. It supports the shift toward renewable and compostable packaging by providing processability without compromising clarity or performance.

    Industry compliance standards

    • EU Regulation (EC) No 10/2011—Plastic materials for food contact
    • FDA 21 CFR 177.1670 (plastics for food packaging)
    • ASTM D6400 (Compostable Plastics Standard)
    • ISO 9001 (Quality Management Systems in film production)

    Typical usage ratio

    • 0.5%–8% by polymer weight; specific dosage governed by polymer type and intended migration resistance

    Downstream process integration

    • Blending with resin granules prior to extrusion; co-feed to melt compounding steps to ensure uniform distribution and plasticizing effect

    Final product types

    • Food wrapping films
    • Biodegradable plastic bags and agricultural mulch films
    • Medical device packaging sheets
    • Flexible tubing and industrial sheeting

    6. Lipid Nanoparticle and Drug Delivery Systems

    Life science ingredient manufacturers incorporate monoolein in the formulation of lipid nanoparticles and microemulsion systems for encapsulation and delivery of peptides, mRNA, and hydrophobic actives. Its capacity to form stable cubic phases makes it vital for precision drug delivery and next-generation vaccine carriers.

    Industry compliance standards

    • ICH Q8 Pharmaceutical Development
    • USP General Notices and Requirements for Excipients
    • WHO Technical Report Series on pharmaceutical nanomaterials
    • EU GMP Annex 13 for Investigational Medicinal Products

    Typical usage ratio

    • 10%–40% of total lipid phase, optimized by target compound and delivery platform (nanoemulsion, cubosome, etc.)

    Downstream process integration

    • Co-milling, high-pressure homogenization, or solvent evaporation to develop nanodispersions; sterilization by filtration for parenteral applications

    Final product types

    • Lipid nanoparticles for injectable mRNA vaccines
    • Oral and IV nanoemulsion drug carriers
    • Targeted transdermal delivery systems
    • Diagnostic imaging agents
    Free Quote

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    Certification & Compliance
    More Introduction

    Monoolein: A Practical Look at an Essential Lipid Ingredient

    Getting to Know Monoolein: Why We Make It

    Monoolein shows up in more industries than people expect. Here at the factory, every batch starts the same way—from basic, reliable raw oleic acid and pure glycerol. Heating, mixing, then carefully controlling the reaction gives us monoolein: a monoglyceride, mostly the 1-monooleoyl form. Our plant sticks to these standards because customers notice when something changes, even a little.

    Most requests come for monoolein with a purity above 98%, tested by gas chromatography. Too many side products—from sloppy processing or cheap shortcuts—cause headaches down the line. Residual di- and triglycerides aren’t just a technical glitch. They foul up emulsification, create haze in cosmetic bases, or even turn edible fats rancid faster. We keep monoolein clear and pale yellow, with minimal odor, and pack it up in lined drums or bulk tankers. Water and acid numbers matter to users—so we make sure the product holds fast to specs batch after batch.

    Inside the Factory: Process Experience

    Years on the production floor have taught us that temperature swings during esterification can easily ruin a whole lot. Not watching water-off rates leaves monoolein mixed with heavy diester. Operators keep a close eye on every stage—this isn’t a process to run by formula alone. Extraction, refining, and deodorizing all determine if the finished monoolein will stand up in pharmaceuticals or food blends. Skipping over vacuum drying or overshooting the vacuum can introduce odd smells and raise acid values. Quality control samples get taken from every batch because we’ve seen how a small miss here means million-dollar recalls for clients later.

    We have heard stories from other plants that turn out muddy, off-color monoolein just because shortcuts seem easier during busy months. Yet downstream customers always notice. In surfactant applications, dark tints mean extra pigment cost or repeated blending tries. In injectable pharmaceuticals, even tiny residues disqualify a batch. From our experience, repeated distillation with careful monitoring always pays off. Monoolein should pour at room temperature and not turn waxy at 10°C. Years of tweaking the purification steps let us keep the product at these standards, so formulating teams can use it right out of the drum with minimal testing.

    What Makes Our Monoolein Stand Out

    Our approach focuses on delivering monoolein with true single-peak chromatograms. Some market options show multiple minor by-products—those end up fouling delicate food emulsions or cause product separation after storage. A trusted factory-standard monoolein will tolerate long-term storage without separating or giving off acid odors. Detailed batch records, retained samples, and tight process checks prove the point: each production lot qualifies for pharmaceutical and food certifications where needed.

    Customers tell us over and over how badly off-flavors or clouding from impure monoglycerides upset their work. We avoid that by going the extra mile in cleaning up the product, not just relying on crude first-cut distillate. The fatty acid profile is nearly pure oleic, rarely dipping below 92%, and trans-fat content stays well under legal limits. Polished monoolein, low in moisture, reduces spoilage risk, especially in international shipments or large warehouse storage. This approach results in lengthy shelf-life and consistently transparent batches, even after months in a warehouse.

    Monoolein in Food: Emulsifier, Softener, Stabilizer

    Food manufacturers come to us with detailed requirements, not just for purity, but for dependable function in their processes. Monoolein plays a role as an emulsifier in whipped toppings, cake shortenings, and reduced-fat spreads. It helps bind water and oil phases, giving products their familiar texture. When the monoolein doesn't meet spec, topping breaks, cake crumbs collapse, and frozen desserts crystalize. Having worked with bakeries and creameries, we've learned that monoolein's soft fat content keeps dough flexible and fillings creamy, especially in products held over several days or subjected to freeze-thaw cycles.

    Our monoolein often acts as a crystal inhibitor—no one wants grainy chocolate or icy icing. Fats that blend well at low temperatures prevent these flaws. Over time, industries have adopted monoolein to replace synthetic emulsifiers or problematic animal fats. We've had clients switch over to our plant’s monoolein after failed tests with cheaper blends, just to avoid unappealing mouthfeel or unwanted labeling issues in clean-label applications.

    Every season, customers ask about the difference from standard mono- and diglyceride blends. Monoolein’s sharp melting point proves invaluable for managing the consistency of margarine and spreads. It breaks air into tiny bubbles, producing finer and longer-lasting texture in whipped foods—a trait that diglyceride-rich blends lack. We have seen factories save on ingredient costs after moving to monoolein as a single-function emulsifier, streamlining recipes rather than relying on stacked blends of imported additives.

    Monoolein in Pharma: Lipid Carrier and Delivery Vehicle

    The pharmaceutical industry looks for monoolein that meets high purity thresholds and traceability. Our processes achieve levels demanded by injectable and oral formulation teams. Monoolein provides the backbone for structured lipid nanoparticles and is often chosen as the oil phase in liquid crystal matrices. We field detailed questions from researchers about phase behavior and viscosity, since poorly defined batches mean costly losses and regulatory hassles.

    Lab teams working on sustained-release implants or oral capsules often want guaranteed lot-to-lot consistency. We screen every batch for heavy metals, residual solvents, and microbial contamination. Years ago, inconsistent monoolein sources forced formulators to make complex corrections or throw away pilot samples. Rather than force customers to test everything themselves, we offer real, testable COAs and the facility to ship reference retains for every order. Through direct communication with R&D departments, our technical staff helps researchers plan for scale-up or transition from lab to plant without repeated troubleshooting.

    Monoolein’s gentle matrix formation stores water-insoluble drugs and releases them at a controlled pace. We have seen it support better uptake in oral dosage forms, which can't be matched by typical triglyceride carriers. Its biocompatibility and food-grade status mean a smoother path through regulatory hurdles. A customer switched to our monoolein after months spent resolving precipitation and slow drug release with other fats—one change saved months of reformulation and regulatory work.

    In Cosmetics, Monoolein Shines

    Monoolein forms the core of many modern creams, lotions, and ointments. Its smooth texture and moisture-retention properties hydrate skin and soften bases without stickiness. We host regular audits and open up our process to cosmetic chemists, who need to know about every additive and impurity. Synthetic blends sometimes leave a heavy or occlusive feel, an issue we help resolve with fresher, cleaner monoolein.

    We’ve supported brands transitioning from old mineral oil emulsifiers to naturally derived monoolein. Across many trials, the mildness and clean profile of monoolein lower the risk of irritation. Our production team ensures low peroxide and acid values, which translate to longer shelf life in finished creams. Marketing teams also ask for sustainable and non-GMO certified batches—monoolein sourced from verified vegetable oils makes labeling more straightforward.

    Consistent quality results in stable creams and lotions, avoiding oil separation and “gritty” texture. Our technical advisers work with customers to ensure their fragrance oils and actives blend easily into the monoolein base. Every cosmetic formulator looks for that combination of high spreadability and a silky after-feel, something we’ve spent years refining through process tweaks and feedback from customer production lines.

    Why Not Just Use Generic Monoglycerides?

    Often, procurement teams ask if industrial monoglyceride blends will do the same job. Having watched process lines firsthand, we know generic products come loaded with a mix of saturated and unsaturated chains, diesters, and unknown origins. These variables cause product failures—poor emulsification, flavor contamination, and textural inconsistencies. We routinely test samples sent by customers who tried low-cost mono-diglycerides, then come back for our monoolein because it simply works without troubleshooting.

    Monoolein melts at 34-36°C and goes down clear, behaving predictably under heat. Blends containing palmitic, stearic, or lauric monoglycerides shift melt points up or down, causing separation or waxiness after packaging. Surface-active properties change, sometimes leading to frothing or film formation instead of true emulsification. In cold confectionery or frozen desserts, impure monoglyceride blends can promote graininess. Our team shows the value of a tight specification by running parallel tests using factory-made cakes, ice cream, and spreads—differences in mouthfeel and stability appear quickly.

    Monoolein’s high purity gives it a neutral taste and scent, making it a favored base for delicate recipes or fragrance-sensitive products in pharma and foods. Health-focused customers appreciate the low-saturated fat content compared to hydrogenated mono- and diglyceride blends. On the regulatory side, clean label claims are easier to support with a single, traceable ingredient. Ingredient transparency wins acceptance across health, wellness, and pharmaceutical brands.

    Maintaining Stability: Protecting Quality Through the Supply Chain

    Shipping delicate monoolein across climates takes preparation. We load bulk shipments into lined drums or ISO tanks under nitrogen blanketing to minimize oxidation. After years packing monoolein for international transport, we’ve seen containers exposed to sun, heat, and even salt spray. Our technical packaging team runs real-time and accelerated shelf-life tests, tracking color and acid value through simulated shipping routes. Monoglycerides made without strict air exclusion or packaged in thin drums quickly yellow and pick up odor, especially in sea shipments.

    To guard against spoilage in warehousing, we monitor temperature data loggers inside shipment containers and recommend cool, dry storage away from sunlight. Supply chain partners with up-to-date receiving practices reduce risk further. Should unexpected container delays occur, we offer rapid replacement backed by inventory kept on hand at major ports to meet urgent orders. We've supported emergency remanufactures many times due to global shipping upsets—consistency in packing and dispatch handling proved the difference between satisfied repeat buyers and nervous one-off clients.

    Improving Process—Lessons from the Manufacturing Floor

    Every shift, operators log process data, troubleshoot, and examine finished monoolein for off-spec samples. The smallest missed step—a fluctuating vacuum, a blocked condenser, inattention to temperature—cascades into inconsistent batches. We have tested every cleaning protocol, filter medium, and reaction sequence over years of production. Not every improvement happens at the first try. We keep samples in reserves and regularly review old batches, learning from both successes and mistakes.

    Working alongside maintenance teams, we document replacement schedules and swap out critical gaskets to control contamination. Routine equipment upgrades mean upgrades in output quality, and a walk through our plant shows an operation clean enough for pharma but built for industrial volumes. Our commitment to continuous training and internal audits reflects in customer satisfaction records and low complaint rates.

    Collaborating with process engineers and customer R&D teams, we adapt batch sizes, test different cooling and filtration techniques, and validate every modification in live runs. When major clients change their formulations, we get early warning and start pilot batches. This partnership between client and factory lets us stay agile; last-minute adjustments don’t throw our operations off track, since every team—from QC to tank cleaning—knows the stakes and responds quickly.

    R&D and Innovation in Monoolein Production

    The need for new grades of monoolein comes up as industries push for different performance or ecological ratings. We’ve worked with research teams to craft higher HLB grades for specific emulsion types, and we’re expanding into organics using stricter plant-based inputs. Researchers from biopolymer or drug delivery startups sometimes request custom batches, which we can offer thanks to in-house lab resources. Nothing boosts our process knowledge like running side-by-side comparisons of different feedstocks and refining agents under real operating conditions.

    During development, the focus stays on removing catalyst, lowering residue counts, and increasing purity for advanced pharma applications. Cleaner process chemistry means less risk of side reactions that could show up months later in long-term storage stability tests. Years of production data help us spot trends in fatty acid content shifts caused by crop variation. When a customer’s results deviate, our tech teams dig back through retained samples and production logs to find a cause and recommend a fix. Ongoing partnerships with end users—whether food engineers or medical formulation groups—help us stay ahead of shifting regulatory and commercial needs.

    Environmental and Compliance Responsibility

    We see the changes in the global regulatory framework day in and day out. To support customers facing stricter food and pharma requirements, we certify monoolein batches as free from harmful additives, genetically modified inputs, or animal products. Downstream users want to avoid allergen risks and build cleaner supply chains. Our sourcing keeps up with these needs, relying on strictly segregated raw materials. Regular audits and batch traceability give proof.

    Waste treatment from the monoolein process receives the same attention as the main product line. By recovering glycerol and reprocessing spent catalysts, we keep environmental impacts low and minimize discharge. This reduces costs for us and delivers peace of mind to customers facing environmental review or ISO audits. Over years, we've adopted newer, high-efficiency thermal recovery and emissions control throughout the plant. We keep open records on solvent and effluent management, gaining trust from multinational brands that require environmental stewardship in their supplier chain.

    Supporting Customers: Technical Service & Real-Time Troubleshooting

    Many incoming requests start with a customer complaint about failed production runs. Our experience includes late-night troubleshooting with bakery lines, pharma trial runs, and even emergencies with packed shipments held up at major ports. Our technical service teams field calls, review process data, and send out counter-samples for validation. Many clients count on us as a backstop, knowing that we keep extra monoolein on hand for rapid turnaround. Success depends on both tight QC and the flexibility to pivot production when urgent support is needed.

    Customers also value our willingness to tackle small custom runs for pilot projects or research batches. Over time we've built a library of application knowledge—what happens in real-world systems, what causes product failures, and how to fix issues before they grow. Field experience beats textbook answers every day, and we share those insights across industries to improve both our own output and customer results.

    What Customers Gain by Working Direct with a Manufacturer

    Commercial users come to us, not for generic commodity ingredients, but for monoolein that fits into processes without downtime or unexplained problems. By overseeing every step from sourcing through final packing and working with buyers on shipping, we offer stronger control and quicker response than any distributor or resale partner. We treat every complaint or development project as another opportunity to deepen our expertise—and to deliver products that keep production lines running smoothly.

    For over a decade, we’ve learned by seeing what goes wrong in real-world use—failed emulsions, missed regulatory marks, unstable product in cold chains. Factory experience shows that a single bad ingredient batch can throw off major production lines, costing far more than a supposed bargain saves. Listening to line operators and formulation chemists has shaped our approach. Every upgrade in our process, every shipment that arrives on time and on spec, strengthens our role as a reliable partner, not just a background supplier.

    Monoolein isn’t just a line on a spreadsheet—it’s a bridge between raw natural resources and the consumer products people rely on. Quality and consistency turn basic chemical processing into real-world results—creamy spreads, gentle lotions, stable drug formulations. Factory knowledge, long-term commitment, and continual improvement remain at the core of how we make and deliver monoolein for today’s demanding users.