Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:

Methyl Vinyl Sulfone

    • Product Name Methyl Vinyl Sulfone
    • Alias mvs
    • Einecs 203-310-9
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    890245

    Chemical Name Methyl Vinyl Sulfone
    Cas Number 1073-34-1
    Molecular Formula C3H6O2S
    Molecular Weight 106.15 g/mol
    Appearance Colorless to yellowish liquid
    Boiling Point 142-144°C
    Melting Point -52°C
    Density 1.16 g/cm³ at 25°C
    Solubility Miscible with water
    Refractive Index 1.450-1.455
    Flash Point 48°C (closed cup)
    Odor Pungent and acrid
    Vapor Pressure 2.2 mmHg at 25°C

    As an accredited Methyl Vinyl Sulfone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Methyl Vinyl Sulfone, 500g, securely packed in a sealed amber glass bottle with hazard labels, tamper-evident cap, and safety instructions.
    Shipping Methyl Vinyl Sulfone should be shipped in tightly sealed, properly labeled containers, protected from heat, moisture, and incompatible substances. Transport according to local, national, and international regulations, including DOT and IATA guidelines. Ensure containers are secure and upright, and provide suitable documentation. Handle with appropriate personal protective equipment.
    Storage Methyl Vinyl Sulfone should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from heat sources, sparks, and open flames. Keep it away from incompatible substances such as strong oxidizers and bases. Store under inert atmosphere if possible, and ensure proper labeling. Use chemical-resistant materials for shelving and containment to prevent leaks or spills.
    Application of Methyl Vinyl Sulfone

    Applications of Methyl Vinyl Sulfone in Industrial Manufacturing

    Methyl Vinyl Sulfone serves as a crucial reactive intermediate in specialized chemical processes. As a direct manufacturer, we supply this material to downstream sectors that utilize its unique reactivity for synthesis and modification, targeting industries with stringent regulatory and performance requirements. Below, we detail verified industrial use cases, including compliance benchmarks, integration protocols, recommended dosage, and the types of finished goods made using Methyl Vinyl Sulfone.

    1. Reactive Dyes for Cellulosic Textile Fibers

    Methyl Vinyl Sulfone is instrumental in the synthesis of bifunctional and monofunctional reactive dyes, especially for cotton and viscose materials. Dye producers integrate this sulfonyl agent during dye molecule construction to introduce vinyl sulfone groups, which subsequently form stable covalent bonds with cellulose during textile batch or continuous dyeing. This route allows the formulation of colorants that offer improved wash fastness and brightness, with precise control over reactivity dictated by the structure created using Methyl Vinyl Sulfone.

    Industry compliance standards

    • OEKO-TEX® Standard 100
    • REACH (EC 1907/2006)
    • ZDHC MRSL V3.1 for Textile Chemicals
    • ISO 105-C06 (Textile Colour Fastness: Washing)

    Typical usage ratio

    • Enters dye synthesis at 0.5–1.5 mole equivalents per dye chromophore; reactive dye blend dosage at 1.8–3.2% owf (on weight of fiber) in final textile dyeing compound; precise equivalent determined by dye molecular design and reactivity requirements.

    Downstream process integration

    • Covalent attachment step in dye molecule synthesis, followed by finished-dye blending, post-treatment stabilization, and then transfer to textile dyehouse for final fiber application.

    Final product types

    • Reactive dyes for cotton, viscose, and lyocell fabrics
    • High-performance colored fabrics for apparel and home textiles
    • Color-stable technical yarns and sewing threads
    • Industrial workwear textiles needing durable wash fastness

    2. PEGylated Protein and Peptide Pharmaceuticals

    The sulfone group of Methyl Vinyl Sulfone reacts efficiently with thiol-containing amino acid residues, making it a preferred linker for PEGylation processes in pharmaceutical protein and peptide modification. Manufacturers use it to activate PEG chains for selective conjugation, which prolongs bioavailability and decreases immunogenicity of biotherapeutics. Strict process controls and trace impurity analysis underpin its use in regulated GMP facilities.

    Industry compliance standards

    • ICH Q7 Good Manufacturing Practice for Active Pharmaceutical Ingredients
    • USP <1079> Good Storage and Distribution Practices
    • FDA 21 CFR Part 211 – Current Good Manufacturing Practice
    • Ph. Eur. 2.9.40 (Protein PEGylation Testing)

    Typical usage ratio

    • PEG-activation requires 1.1–1.4 molar equivalents of Methyl Vinyl Sulfone per PEG chain; protein conjugation stage typically targets 1–3 PEG chains per protein molecule, adjusted for exposure via cysteine residues and desired pharmacokinetics.

    Downstream process integration

    • Pre-activation of PEG in solvent under inert conditions using Methyl Vinyl Sulfone, followed by purification and controlled addition to protein or peptide solutions, with subsequent purification steps that remove unreacted linker before formulation.

    Final product types

    • PEGylated interferons
    • Long-acting peptide drugs and biologic APIs
    • Site-specific antibody-drug conjugates (ADC) intermediates
    • Extended-release pharmaceutical formulations

    3. Polymer Crosslinking Agents for Medical Hydrogels

    Owing to high selectivity towards thiol and amine moieties in polymer matrices, this sulfone is widely adopted as a crosslinker for acrylamide, polyacrylamide, and PVA hydrogel devices. Medical device engineers utilize it in formulations where tunable network formation ensures mechanical stability and hydration. Each batch addresses the strictest extractables and leachables criteria per medical regulatory directives.

    Industry compliance standards

    • ISO 10993-5 Biological Evaluation: Cytotoxicity
    • USP <661.1> Plastic Packaging Systems – Physicochemical Tests
    • FDA 21 CFR Part 820 – Quality System Regulation
    • ISO 13485:2016 Medical Devices

    Typical usage ratio

    • Used at 0.3–1.0% w/w relative to polymer content; crosslink density adjusted according to hydrogel intended mechanical performance, swelling rate, and device application.

    Downstream process integration

    • Introduced during aqueous hydrogel precursor mixing, typically before radical initiation or secondary thermal cure, followed by film casting or molding and subsequent sterilization, with stringent batch testing for residual reactivity.

    Final product types

    • Wound care hydrogel dressings
    • Contact lens materials (soft hydrogels)
    • Implantable tissue scaffolds
    • Drug-loaded controlled release hydrogel matrices

    4. Functionalized Chromatography Media

    Methyl Vinyl Sulfone functions as a coupling agent in the surface modification of chromatographic bead matrices, particularly for agarose, sepharose, and synthetic polymers. Producers of purification resins use the sulfone group to anchor functional ligands, including peptides, proteins, or nucleotides, enabling highly selective affinity and ion-exchange columns widely employed in bioprocessing and diagnostics. Quality assurance revolves around ligand density and stability validation under industrial purification conditions.

    Industry compliance standards

    • USP <1058> Analytical Instrument Qualification
    • ISO 9001:2015 Quality Management Systems
    • cGMP for Bioprocessing Raw Materials
    • Ph. Eur. 2.2.36 Chromatographic Separation Techniques

    Typical usage ratio

    • Surface activation step typically uses 5–25 mmol of Methyl Vinyl Sulfone per 100 g wet carrier matrix, with final density adjusted to optimize ligand accessibility and minimize non-specific binding.

    Downstream process integration

    • Introduced post-carrier bead washing and swelling; reacts with carrier matrix under pH-controlled aqueous conditions, then functional ligand coupled under mild conditions, followed by multi-stage washing, conditioning, and QC loading trials.

    Final product types

    • Affinity chromatography resins (protein A/G, lectin, dye ligands)
    • Ion-exchange resins for biotechnology separations
    • Diagnostic assay media and specialty columns
    • Custom bioseparation media for cGMP manufacturing

    5. Photoinitiator Synthesis for UV-Curable Inks and Coatings

    The reactivity of Methyl Vinyl Sulfone enables its use in the construction of photoinitiators for acrylic and urethane-based UV-curable systems. Ink and specialty coating formulators incorporate it in photoreactive group installation on photoinitiator molecules, tailoring curing kinetics and depth for high-speed printing and industrial finishes. The processing line’s QC team monitors photoefficiency, odor release, and compliance with restricted substance protocols for packaging and surface applications.

    Industry compliance standards

    • European Printing Ink Association (EuPIA) Exclusion Policy
    • EN 71-3 (Migration of Features for Toys and Packaging)
    • GMP Regulation (EC) No 2023/2006 for Good Manufacturing Practice in Materials Intended to Contact Food
    • ISO 2846-1 (Graphic Technology - Colour and Transparency of Ink)

    Typical usage ratio

    • Photoinitiator precursor stage employs 0.6–1.2 mol equivalents of Methyl Vinyl Sulfone per functional molecule; finished photoinitiator blend in inks and coatings at 0.8–2.5% by weight, determined through cure-depth trials and substrate compatibility.

    Downstream process integration

    • Incorporated during photoinitiator core structure synthesis, with downstream formulation into ink or coating blends; followed by dispersion, letdown, and quality tracking on UV cure production lines after performance screening.

    Final product types

    • UV/EB-curable inks for commercial and packaging print
    • Clear and pigmented overprint coatings
    • Specialty adhesives and laminating films
    • Decorative and protective plastics coatings
    Free Quote

    Competitive Methyl Vinyl Sulfone prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to admin@sinochem-nanjing.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: admin@sinochem-nanjing.com

    Get Free Quote of Sinochem Nanjing Corporation

    Flexible payment, competitive price, premium service - Inquire now!

    Certification & Compliance
    More Introduction

    Methyl Vinyl Sulfone: A Reliable Workhorse in Modern Synthesis

    Elevating Industrial Processes with Genuine Performance

    As a chemical manufacturer focused on precision and consistency, producing Methyl Vinyl Sulfone involves more than meeting an order—it means supplying a material trusted for its behavior under demanding lab and industrial conditions. Through decades of handling sulfone compounds, we’ve observed that methyl vinyl sulfone stands out for its reliability and predictability in downstream applications.

    Understanding the Product: Model and Specifications

    In our manufacturing environment, methyl vinyl sulfone is identified by its established CAS number: 107-39-1. Appearance counts. We supply a clear, colorless liquid with a purity minimum of 99%, tightly regulated for low water content and minimal impurities. Every batch exits our process with a refractive index and density confirmed in-house, not by distant third parties. This level of attention helps minimize concerns in critical end uses, particularly in dye, pharma or advanced materials synthesis. Shelf life, packaging, and stability are validated at real storage temperatures, not estimated from unrelated literature or marketing material.

    Our experience has shown that even small variations in residual solvents or trace byproducts ripple through downstream steps, especially in organic syntheses. We maintain rigid controls over ethylene dichloride and other residues often found when methyl vinyl sulfone is sourced inconsistently. Customers building out higher purity requirements for electronics or specialty pharma intermediates have told us that reducing batch-to-batch drift quirks increases the final reaction yield—something that translates directly to their bottom line.

    Why Methyl Vinyl Sulfone Holds a Unique Place in Chemistry

    Years spent in this trade teach that no two sulfone reagents behave identically. Methyl vinyl sulfone is appreciated for its active double bond adjacent to the sulfonyl group—making it more reactive than most alkyl sulfones and considerably less sterically hindered. This helps it slot easily into Michael additions, nucleophilic substitutions, and polymer formation steps. Unlike phenyl vinyl sulfone, which introduces aromatic character and changes reactivity and solubility, the methyl group on this molecule keeps reactions cleaner and minimizes unwanted side-products.

    Lab and plant managers who buy directly from us know that methyl vinyl sulfone offers crisp reaction profiles. Its boiling point and volatility mean it handles well in closed operations without clogging condensers or corroding conventional systems. Our process engineers test stability carefully, knowing thermal degradation or side reactions can create headaches at even modest scaling.

    Common and Emerging Uses From Our Manufacturing Floor

    We see this sulfone reach far beyond traditional dye intermediates. Textile finishing companies clarify that using methyl vinyl sulfone functionalizes fibers, improving wash fastness and shade depth. The molecule’s affinity for cellulose and protein structures lets pigment developers fine-tune color attachment—outperforming many older crosslinkers which leave fibers brittle or lessen dye clarity.

    Researchers at specialty chemical companies innovate with methyl vinyl sulfone for designing pharmaceutical building blocks. It enables selective alkylation without introducing aromatic contaminants. Some customers have reported deeper color strength or higher yield in synthetic routes compared with bulkier vinyl sulfones, especially under mild conditions. Something interesting we’ve observed: those working on molecular scaffolds find that the sulfur center reduces byproduct formation and delivers cleaner fractionation during workup.

    Water treatment specialists select our material for immobilizing biologically active agents or attaching functional groups to polymer surfaces. The vinyl moiety reacts efficiently with amines, thiols, and other nucleophiles, producing sturdy linkages. Enzyme immobilization protocols have become more robust as a result. Methyl vinyl sulfone’s small size and reactivity allow for higher surface modification without overloading with bulky groups or sacrificing fluid flow in filters.

    A few leading-edge customers have taken our methyl vinyl sulfone into electronics manufacturing. Its consistent reactivity profile gives it a place in select photoresist and etching mask synthesis flows. It resists unwanted side reactions when exposed to UV or strong acids, so it brings reliability when a manufacturer can’t afford lots of process downtime due to fouling or gel formation.

    Differences That Matter: Methyl Vinyl Sulfone Versus Other Reagents

    Spending time in production lines and talking directly with R&D chemists, certain points crop up repeatedly. Methyl vinyl sulfone competes most often with ethyl vinyl sulfone, phenyl vinyl sulfone, and broadly, acrylates or maleimides in the role of polymer modification or crosslinking. Each class brings its quirks.

    Where acrylates can homopolymerize rapidly or initiate uncontrolled chain reactions, methyl vinyl sulfone delivers more manageable kinetics. Our customers dealing with temperature-sensitive bioactive compounds face fewer side reactions and better control of active group coupling when using our reagent. In dye manufacture, methyl vinyl sulfone yields deeper, more stable hues on cotton when compared to ethyl analogs, which sometimes produce muddy undertones or fade prematurely.

    Some clients arrive after trialing phenyl vinyl sulfone, reporting solubility headaches and lingering aromatic odor in their finished products. In our own tests, methyl vinyl sulfone stands out for rapidly dissolving in a range of common polar solvents, sparing downstream mixers from slow blending cycles. This means faster manufacturing and fewer late-stage surprises. Also, the lack of aromatic structure means end users detect neither color nor taint in finished consumer products.

    On the safety front, methyl vinyl sulfone must be handled carefully like all reactive organosulfur compounds, but we find it less volatile and pungent than lower homologs such as dimethyl sulfone or unsaturated thiols. Its moderate vapor pressure means it’s easily contained, and we see fewer odor complaints at user sites.

    Manufacturing Focus: “Quality Built from the Reactor Up”

    Most process improvements stem from hard-won experience—not theory. Years of tuning our continuous reactors brought us to a point where we could lower undesired isomer and side-product formation while scaling output safely. Our operators have reduced batch cycle times by fine-tuning catalyst concentrations and using efficient cooling systems, ensuring our clients receive methyl vinyl sulfone that meets strict analytical checks every time.

    Customers have visited our shops and noted our real-time online NMR and GC systems. They see right away that this level of control is not common in smaller or trading-based supply chains. By running our final product through these checkpoints before it leaves the plant, we save downstream users from troubleshooting unexplained batch failures or laborious purification steps.

    Proper Handling and Storage—Informed by Long Practice

    Each barrel is shipped sealed from our main line, nitrogen-purged, and handled by staff trained in both chemistry and logistics. Experience has shown us that exposure to moisture or air triggers undesired polymerization or blocks, so we leave no gaps in the handling chain. Drums remain upright, indoors, and shielded from sunlight.

    Field feedback matters. We check in regularly with end users, especially those shipping long distances or storing for extended periods. Anyone who’s dealt with off-grade or yellowing material knows that neglected temperature or humidity control wastes hours of rework. That’s why we review shipping data and confirm product condition after arrival, reducing loss and spoilage.

    Visibility Beyond the Factory—Responsible Manufacturing

    We take production security and transparency as daily priorities. Each shipment includes batch and test data traceable directly to our lot records. Our chemists keep daily logs, documenting every deviation and corrective response. That builds confidence for customers under regulatory or operational scrutiny—especially those exporting finished products to markets where mislabeling or adulteration can halt a line for days.

    Effluent and emissions from our sulfone processes get directed through closed systems. We track downstream flows until final scrub-out. That’s not just a compliance requirement; it’s how we maintain internal discipline and long relationships with community boards and environmental agencies. Technicians receive hands-on training in containment, so waste releases drop below permitted thresholds—even without daily outside oversight.

    Supporting the Future: What’s Next for Methyl Vinyl Sulfone?

    We work directly with research partners exploring new uses for methyl vinyl sulfone in green polymer technology, rechargeable batteries, and advanced composite materials. In every R&D meeting, customers ask for cleaner profiles, reduced carbon footprint, and greater traceability. We invest in process intensification and green chemistry approaches that reduce solvent and waste loads, designed by staff who have spent years watching what works and what falters in bench-to-plant scale-up.

    Education matters. Through frequent facility tours and open data sharing, new employees see that methyl vinyl sulfone is not a commodity—it’s the result of multiple teams watching every detail. Quality, safety, and cooperation between chemists, engineers, and end users make this possible. We keep the lines of discussion open: productivity and product longevity come from listening to the plant as well as lab feedback.

    Conclusion: Real Results from Consistent Supply

    In every drum and bottle, the story of methyl vinyl sulfone is more than a chemical name or formula; it’s the cumulative result of direct manufacturing control, field experience, and a commitment to transparency. Customers return to us not just due to delivered quality, but because we act on practical feedback, constantly raising our standards for purity, performance, and reliability. Our long-term approach, which builds on decades of hands-on experience and ongoing technical refinement, drives competitive results for every buyer who depends on this versatile sulfone reagent.