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HS Code |
301090 |
| Cas Number | 623-07-0 |
| Molecular Formula | C9H10O2 |
| Molecular Weight | 150.18 g/mol |
| Synonyms | Methyl o-toluate, o-Toluic acid methyl ester |
| Appearance | Colorless liquid |
| Boiling Point | 216-218 °C |
| Melting Point | -16 °C |
| Density | 1.06 g/cm3 |
| Refractive Index | 1.514-1.516 |
| Flash Point | 98 °C |
| Solubility In Water | Insoluble |
| Odor | Aromatic |
| Smiles | COC(=O)C1=CC=CC=C1C |
As an accredited Methyl O-Toluate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Methyl O-Toluate is packaged in a 500 mL amber glass bottle with a secure screw cap, clearly labeled for laboratory use. |
| Shipping | Methyl O-Toluate is shipped in tightly sealed containers, protected from moisture, heat, and direct sunlight. Ensure containers are upright and clearly labeled. Handle with care to prevent leakage or spills. Comply with local and international regulations for safe chemical transportation. Suitable protective equipment is required during loading and unloading operations. |
| Storage | Methyl O-Toluate should be stored in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible materials such as strong oxidizers. Keep the container tightly closed and protected from direct sunlight. Store in a designated flammable liquids area. Ensure containers are clearly labeled and handled with appropriate personal protective equipment to prevent spills and exposure. |
Applications of Methyl O-Toluate in Industrial ManufacturingAs the primary manufacturer of high-purity Methyl O-Toluate, we support diverse industrial production chains with specialized grades tailored for controlled downstream use. Below, we detail verified application fields, each with distinct regulatory, formulation, process, and performance requirements. All information reflects actual practice in current global markets. 1. Fine Fragrance Compound ManufacturingMethyl O-Toluate provides a blended sweet, floral, and balsamic note highly valued in fine fragrance compounding. Perfumers incorporate this ingredient to create complex base accords in designer perfumes, colognes, and luxury body sprays. Its compatibility with essential oil extracts and fixatives supports stable diffusion characteristics across alcohol and oil-based formulations, providing lasting olfactory balance. Industry compliance standards
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2. Industrial Solvent Blends for Specialty CoatingsOwing to its controlled evaporation profile and moderate solvent power, Methyl O-Toluate finds practical use in the formulation of aromatic ester-based solvent blends for high-performance metal and wood coatings. Its inclusion refines flow, gloss, and film integrity while minimizing surface defects in specialty primer and enamel applications requiring precise solvent balance. Industry compliance standards
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3. Pharmaceutical Intermediate SynthesisPharmaceutical producers use Methyl O-Toluate as an intermediate for steps in the synthesis of select active ingredients and specialty intermediates. Its chemical reactivity, particularly as a methylbenzoate derivative, supports reliable downstream functionalization via Friedel-Crafts or esterification reactions within GMP-controlled environments. Industry compliance standards
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4. Aroma Ingredient for Flavor and Fragrance AdditivesFood flavoring houses employ Methyl O-Toluate to impart a sweet, floral, slightly fruity aroma in compounded flavors for beverages, bakery products, and confectionery. Its stability under food processing conditions, along with its harmonizing effect in ester-type flavor profiles, makes it valuable for authenticating fruit and floral notes. Industry compliance standards
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5. Intermediate for Agrochemical FormulationsMethyl O-Toluate enables specific esterification steps crucial in the synthesis of advanced agrochemical intermediates, particularly for selective herbicides and plant growth regulators. Downtime reduction and controlled reactivity allow formulators to enhance active isomer selectivity under regulated production requirements. Industry compliance standards
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There’s no replacement for the time spent on the shop floor, where each batch takes shape and every quality parameter gets checked by us, not just on paper but through hands-on work. Over the years, we have been producing Methyl O-Toluate at scale for customers who understand that consistency defines downstream success in chemical synthesis, flavors, fragrances, and high-purity electronics precursors. Our deep connection with this process lets us speak plainly about what makes this product stand out, where its most reliable applications lie, and how its characteristics affect real-world projects.
Methyl O-Toluate comes from our toluic acid methylation line. We see varying requirements from different sectors, but one point keeps coming back—customers want a clean, uncontaminated ester that won’t introduce surprises into ongoing syntheses or formulations. During distillation, we focus on keeping impurity levels tightly controlled, especially isomeric by-products and water content. The GC purity in our standard batches, routinely checked, reaches above 99%. We favor glass-lined reactors to maintain chemical inertness, and every shipment undergoes per-lot tracking to back up our quality claims.
Specifications show up in requests: color (measured in Hazen units), acidity, moisture, and residual solvents. Some end users have asked about metal residues, so our process includes filtration and regular equipment maintenance. These steps make sense for substances used in electronics or fine-chemical syntheses, where trace metal contamination can end up interfering with catalyst chemistry later down the line. Our liquid Methyl O-Toluate stays pale, stable in glass or HDPE packaging, holding its own without visible decomposition even after months under normal storage.
Firms blending fragrances find the ester note of Methyl O-Toluate round and persistent, less volatile than simple methyl benzoates. There’s an amber, slightly fruity hint that pairs well in top and middle notes. In our practical conversations with perfumers, they credit the ortho substitution for differentiating this ester’s aroma. By tuning the methylation and purification schedule, we support requests for fractions that skew toward single isomers. Larger batch users for chemical synthesis—mainly in pharmaceutical intermediates—want an unwavering supply to meet validation and regulatory needs. We listen closely when someone mentions batch-to-batch reproducibility, because that ties directly to our own process consistency and raw material sourcing.
In high-purity and electronic applications, Methyl O-Toluate serves as a reagent or solvent, especially when operators need a benzylic methyl group positioned ortho for subsequent reactions. The handling and storage requirements do not stray far from those of related esters, but removal of trace oxidants, peroxides, and unwanted isomeric contaminants plays a bigger role. The chemical’s physical stability, paired with its manageable volatility (boiling near 220°C), means users benefit from easier containment and fewer material losses during processing.
Customers often ask how Methyl O-Toluate compares with its para- or meta- counterparts, as well as with methyl benzoate. The molecular similarities mask practical differences that become apparent the moment a batch enters actual synthesis. On the synthetic side, the ortho isomer positions functional groups for controlled reactivity in certain condensation or alkylation paths. We have seen this preference in custom synthesis projects, as some selectivity gets lost with meta or para isomers due to electronic or steric effects.
From a physical perspective, Methyl O-Toluate offers a slightly higher boiling point and lower vapor pressure than methyl benzoate, translating into greater process control in applications requiring gradual temperature ramps or extended holds. Its solubility in a broad sweep of organic solvents (ethers, alcohols, chlorinated solvents) opens the door for flexible process design. Still, the flavor and fragrance producers care most about olfactory profile and purity: here, the ortho isomer produces a warmer, richer note that stands apart from the sharper scent of methyl benzoate or the lighter scent from meta isomers.
Beyond these direct differences, Methyl O-Toluate’s performance in cross-coupling or other catalytic scenarios distinguishes itself by the practical outcome—higher selectivity, better yields, and reduced by-product formation. While ester quality always matters, this is doubly true for users who push the chemistry to its limits and need predictable, robust conversion rates.
From the manufacturer’s side, process knowledge matters more than ever before. Our site handles the methylation of o-toluic acid using dedicated equipment to prevent cross-contamination from other aromatic acids. Temperature control stays tight across each stage to keep by-product formation low, especially at the separation and distillation points. Our processing team takes samples at every phase, measuring GC purity, color, moisture, and, for specialty batches, specific isomer ratios. The finished Methyl O-Toluate gets its approval only after we hit the expected stats for purity, and documentation always follows to give our downstream partners the proof they require for their own quality systems.
While some producers focus only on cost, we hear back from experienced customers who’ve run into trouble with off-odor, discolored blends, or failures in downstream reactions using poorly specified starting materials. These incidents remind us why process vigilance pays off over time. Failures prompt questions about our column maintenance, the chemicals’ in-process storage, and water activity checks. We've learned the hard way that neglecting these steps undercuts both reliability and customer trust.
Working directly with manufacturers on new formulations, researchers appreciate details beyond headline purity. They want data about minor contaminants, residual acidity, and the presence of specific by-products such as dimers or oxidized forms. For instance, if a project target needs tight acidity control, we adjust our neutralization and washing procedures, even running extra lot analysis to hit acid value targets. Some customers, through pilot trials, pointed to the importance of residue film formation: with our process-controlled distillation, the product leaves behind negligible residue, smoothing the work for those in applications using thin film or spinning disk reactors.
Users in the polymer industry count on our ability to keep the chemical clear and colorless, noting that even mild product coloration can give unintended tints to their final goods. Every time we come across a customer charting color readings to find the best feedstock, it reinforces our focus on refining filtration and layout at our plant.
Part of our manufacturing approach involves staying in touch with end-users, not just through sales channels but in technical exchanges and pilot runs. When an R&D team tries a new process route, we discuss solvent recovery, inert gas purging, and packaging transitions to help them achieve the most from their Methyl O-Toluate batches. Some new synthesis pathways in electronics or pharmaceutical precursors have emerged thanks to steady access to well-specified material; accuracy in isomeric purity and low water content has spelled the difference between progress and delay.
Occasionally, questions arise about exploratory applications. We’ve participated in sample trials for specialty coatings, ink foundations, and certain green chemistry processes. In these cases, adaptability becomes more important than volume: we scale small custom batches with the same analytical rigor as larger runs. Over time, feedback lets us improve key quality attributes, so users get a version of Methyl O-Toluate that meets both the standards of regulatory bodies and the practical reality of day-to-day chemists striving for clean reactions without costly troubleshooting.
Producers who order in volume want assurance regarding storage stability and safe packaging. Our Methyl O-Toluate leaves our facility in tightly sealed drums or IBCs, every container nitrogen-flushed for long-haul transit. Users store the product in cool, dry, and well-ventilated locations to avoid contamination and degradation. Reliable drum and container supply chains have become more important with increasing shipping delays; as a direct manufacturer, we keep enough packaging on hand to meet both routine and sudden spikes in demand.
Handling the product in real-world environments means monitoring for small spills and airborne exposure, especially during transfer or sampling operations. We brief user teams about PPE, spill management, and compatible cleaning agents to prevent buildup or stains. Keeping HSE standards at the core of our work, every outgoing batch gets accompanied by a full suite of documentation so customers satisfy their own local EHS compliance inspections. Recent updates in environmental law pushed us to review all raw material supply streams, ensuring both traceability and compliance with regional requirements for VOCs or hazardous labeling.
For us, ongoing reliability takes more than just meeting minimum specs. Customers judge us not only on product but on what happens when shipments run late, when a shipper puts a drum on the wrong truck, or when a seasonal surge in demand threatens to disrupt carefully planned production schedules. Direct communication between our production foremen and customer technical managers has solved more crises than paperwork alone ever could. We believe true risk management lives in those personal conversations and technical support channels, not in catch-all warranties.
Developing contingencies means keeping careful track of upstream raw material supplies, maintaining finished inventory for urgent orders, and doubling up on quality checks for any product flagged for international transport. We have built up relationships with logistics partners who know the difference between sensitive intermediates and ordinary commodity chemicals—this translates directly into lower incident rates, fewer claims, and more predictable project outcomes for our customers.
A regular request we see from sophisticated users relates to tailored batch profiles. Some projects need especially high purity, others require lot-specific reports with full IR, NMR, or customized chromatographic data. We generate these profiles at the plant, so when a user wants full chain-of-custody documentation, we can provide it from the production day forward. Our barcoding and digital tracking systems record every stage, letting customers audit the journey from raw acid to finished ester.
Scalability works both ways: from kilograms for pilot phases to multi-ton campaigns, we run flexible schedules with closely managed changeover and wash cycles to avoid residual contamination. Our experience tells us that trust comes from transparency, not one-off success, so we offer open inspection for regular customers who want to review batch records, quality audits, or even on-site processing standards.
Inevitably, unique issues pop up during new application trials or scale-ups. If a formulation study throws up an unexpected impurity, we collaborate directly with the customer’s lab to map every variable—sometimes even shipping additional retained samples from prior runs for side-by-side comparison. On several occasions, persistent foam or unplanned coloration in finished products led to a redesign of site filtration steps or a revision of solvent handling. These improvements arose not from remote technical paperwork, but from operators and chemists in face-to-face meetings laying out evidence and working toward decisive fixes.
Reaching consensus with R&D and production teams worldwide has encouraged us to push quality even further. Ideas for tighter packaging controls, more sensitive impurity analysis, or continuous process data logging started out as responses to direct feedback and became daily routine. For long-term end users developing new product lines, this steady, incremental improvement delivers benefits felt throughout the product development cycle.
To some, Methyl O-Toluate may seem like just another entry in a long list of chemical esters. For those working at the interface of chemistry, process design, and innovation, every detail in sourcing, handling, and traceability carries weight. Practical success builds on more than molecule counts—it comes from the sum of controlled experience, transparent communication, and a willingness to engage on the level of applied problems rather than generic catalog specs.
After years of running esterification campaigns, managing shipments through tight regulatory turns, and benchmarking purity in real-world labs, we have seen how access to top-tier Methyl O-Toluate keeps projects on schedule, downstream processing efficient, and costs under better control. The collaborative effort between production and end-use applications never stops evolving. We welcome every update from customers, whether it’s a new regulation, a changed spec, or a challenge from a pilot trial. This partnership, rooted in real experience, offers solutions for not just today’s requirements but the demands that tomorrow will surely bring.