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Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate

    • Product Name Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate
    • Alias Ethyl Arachidonate
    • Einecs 246-678-3
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    624061

    Chemical Name Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate
    Cas Number 52309-12-1
    Molecular Formula C16H24O3
    Molecular Weight 264.36 g/mol
    Appearance White to off-white crystalline powder
    Melting Point 77-80°C
    Solubility Slightly soluble in water, soluble in organic solvents such as ethanol and acetone
    Purity Typically ≥98%
    Storage Temperature 2-8°C (refrigerated)
    Synonyms Methyl 3,5-di-tert-butyl-4-hydroxybenzoate, Methyl DTBHB
    Smiles CC(C)(C)c1cc(C(=O)OC)c(O)cc1C(C)(C)C
    Flash Point >110°C
    Ec Number 257-582-5

    As an accredited Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The product is supplied in a 100-gram amber glass bottle, tightly sealed with a screw cap and labeled with compound details and hazard information.
    Shipping Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate should be shipped in tightly sealed containers, protected from light, moisture, and extreme temperatures. The package must comply with chemical transport regulations, include appropriate hazard labeling, and be cushioned to prevent breakage. Transport as a non-hazardous material unless otherwise specified by local regulations.
    Storage Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate should be stored in a tightly closed container, away from direct sunlight, heat, and moisture. Store it in a cool, dry, and well-ventilated area, separate from incompatible materials such as strong oxidizing agents. Ensure proper labeling and keep it out of reach of unauthorized personnel. Follow all relevant safety and regulatory guidelines.
    Application of Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate

    Applications of Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate in Industrial Manufacturing

    Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate is an advanced antioxidant widely adopted in strictly regulated industrial sectors to maintain polymer stability, extend product shelf life, and secure resistance against degradation throughout high-temperature and high-shear manufacturing processes. Below, we detail its main industrial application segments, focusing on operational requirements, integration points, and finalized downstream goods.

    1. Polyolefin Resin Stabilization in Plastic Manufacturing

    Polyolefin producers utilize this antioxidant to counteract the degradation caused by thermal oxidation during polymer synthesis, pelletizing, and extrusion. Industrial resin lines integrate the additive at early compounding stages, ensuring balanced protection for products such as polyethylene and polypropylene. Performance and compliance must align with strict standards on migration and safety, particularly for food-contact plastics and medical-grade components.

    Industry compliance standards

    • EU Regulation (EU) No 10/2011 on plastic materials intended for food contact
    • FDA 21 CFR 177.1520 and 21 CFR 175.300 for polypropylene and polyethylene resins
    • ISO 10993-1 for biocompatibility in medical resin grades
    • REACH Registration, Restriction and Authorization compliance

    Typical usage ratio

    • 0.05–0.15% by weight, optimized based on polymer grade, processing temperature, and required shelf life; higher loads up to 0.20% for medical or food-contact applications

    Downstream process integration

    • Masterbatch compounding, direct blending during melt extrusion, or incorporation in polymerization reactor
    • Quality checks for additive dispersion and melt flow consistency

    Final product types

    • Food packaging films
    • Disposable medical syringes and IV components
    • Automotive bumpers and trims
    • Household containers and toys

    2. Lubricant and Grease Formulations for Automotive and Industrial Machinery

    Formulation chemists in the lubricant sector rely on this antioxidant to prevent base oil oxidation and viscosity breakdown in high-load, high-temperature applications such as engine oils, hydraulic fluids, and grease products. Its performance at suppressing sludge and acid formation under prolonged stress contributes to system reliability and maintenance interval extension, with use permitted under globally harmonized chemical inventories and regional regulations.

    Industry compliance standards

    • API (American Petroleum Institute) lubricant performance specifications
    • ACEA (European Automobile Manufacturers' Association) standards for passenger car motor oils
    • JAMA (Japan Automobile Manufacturers Association) for industrial lubricants
    • OECD guidelines for biodegradability and eco-toxicological safety where required

    Typical usage ratio

    • 0.05–0.4% by weight, adjusted depending on base oil saturation, targeted operating temperature, and product life expectancy

    Downstream process integration

    • Batch blending in heated reactors before oil filtration and bottling
    • Direct addition during grease saponification and homogenization

    Final product types

    • Passenger car engine oils
    • Heavy-duty diesel lubricants
    • Hydraulic system fluids
    • Multi-purpose greases for machinery

    3. Synthetic Rubber and Elastomer Additives in Tire and Footwear Industries

    The antioxidant properties benefit synthetic rubber compounding by protecting finished elastomers from the effects of oxygen, ozone, and heat during both processing and end-use. Tire and technical rubber manufacturers integrate the material to meet extended aging and flex resistance specified by global transportation and environmental authorities.

    Industry compliance standards

    • UN ECE Regulation No. 117 for tire aging and rolling resistance
    • SATRA footwear material standards
    • ISO 9001 certified production systems
    • Automotive OEM rubber specifications (e.g., VW TL 764)

    Typical usage ratio

    • 0.10–0.30% by weight of total elastomer compound, decreased in extended shelf-life shoe soles, increased in off-road tire treads facing aggressive ozone exposure

    Downstream process integration

    • Rubber internal mixing before curing or vulcanization stage
    • Hot melt compounding for calendered sheets

    Final product types

    • Pneumatic and solid tires for automotive and heavy vehicles
    • Industrial conveyor belts
    • Sports and safety footwear outsoles
    • Rubber hoses and molded technical parts

    4. Thermoset and Unsaturated Polyester Resin (UPR) Stability in Composites Industry

    Producers of thermoset resins, particularly unsaturated polyester and epoxy systems, depend on this phenolic antioxidant to inhibit premature cross-linking and discoloration throughout storage, mixing, and molding. The material’s solubility profile aligns with low-VOC composite standards, and supports consistent part performance in advanced construction, marine, and industrial laminates.

    Industry compliance standards

    • ASTM D2583 for reinforced plastics hardness
    • EN ISO 9001:2015 quality management for composite manufactures
    • RoHS Directive (2011/65/EU) for electrical device casings
    • Directive 2002/96/EC (WEEE) for waste electrical and electronic equipment

    Typical usage ratio

    • 0.05–0.20% by weight, tailored based on unsaturation level, presence of accelerators, and cure kinetics

    Downstream process integration

    • Addition during pre-polymer synthesis or final compounding before initiator incorporation
    • Compatibility testing with glass or carbon fiber reinforcements

    Final product types

    • GRP (glass-reinforced plastic) panels and profiles
    • Circuit board laminates
    • Sanitary ware composites
    • Boat hull and automotive body components

    5. Coatings and Varnishes for Metal and Plastic Substrates

    The antioxidant acts as a critical additive in liquid and powder coatings, protecting the polymeric binder systems from photochemical and thermal degradation that can cause color shift, loss of gloss, and brittleness. Its regulatory acceptance for architectural, automotive OEM, and food-contact metal packaging applications enables formulators to achieve performance benchmarks in both solvent and waterborne systems.

    Industry compliance standards

    • US FDA 21 CFR 175.300 for resinous and polymeric coatings
    • EN 71-3 for coatings on toys and childcare articles
    • ISO 12944 for corrosion protection of steel structures by coatings
    • GB/T 9754 for paint film glossiness in packaging coatings

    Typical usage ratio

    • 0.10–0.25% by total binder weight, adjusted for UV exposure, binder chemistry, and end-use temperature fluctuations

    Downstream process integration

    • Premix with liquid binders prior to dispersion grinding
    • Direct addition to powder coating blends before extrusion and micronization

    Final product types

    • Exterior architectural paints
    • Automotive OEM body and trim coatings
    • Internal and external food cans
    • Consumer electronics casings
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    Certification & Compliance
    More Introduction

    Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate: A Closer Look From the Manufacturer’s Floor

    Building a Better Product with Reliable Chemistry

    At our production site, you hear the hum of reactors, see the flow of raw materials, and feel the drive for consistent, reliable chemical quality. We’ve had our hands on Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate since the early demand for specialty antioxidants brought it into sharper focus among resin and polymer producers. Every chemist knows the value of purity, but in manufacturing, you learn quickly that purity alone doesn’t tell the whole story.

    This molecule draws attention because of its unique structure. Those two tert-butyl groups lend impressive steric shielding, making the ester a strong performer where oxidation threatens stability. Each batch we make has a clear, consistent appearance—often a white crystalline powder—though that isn’t the only indicator we worry about. Specifications like melting range and assay frequently top the concerns for polymer applications. In our own labs, experts test each batch for residual solvents, color index, and any sign of unwanted by-products, knowing that even trace impurities can cause downstream issues that haunt plastic or coating producers months later.

    Why We See Demand for This Ester in Modern Polymers

    Anyone who has tried running long polymerization cycles or putting resins through tough weathering tests starts to notice: simpler antioxidants often fall short. It doesn’t take many cycles for some stabilizers to lose their punch. Our own customer feedback confirmed that Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate helped reduce color changes in some polyolefins, slowed yellowing in specialized coatings, and extended the lifetime of polyesters compared to classical phenolic antioxidants. The esterified carboxylic group also reduces the tendency to form insoluble deposits, which means fewer blockages and cleaner extrusion lines.

    From experience, producers have asked for grades with different particle sizes—injectable or for dry blends—because in compounding, how a powder feeds into a line directly impacts work rates and end quality. We’ve invested in production lines that let us tailor mesh size and minimize agglomeration, which our plant team records using real-time image analysis. At this level, small changes mean less dust, better flow, and fewer headaches when handling tons instead of lab beakers.

    Other antioxidants start discoloring under high shear or lose their weight during vacuum or high-temperature conditions. Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate holds up in these challenging spots, and the technical teams running accelerated aging tests point out the difference in lifespan with regular monitoring of UV-exposed samples. Feedback from large-volume molding operations already confirmed the improved shelf stability.

    From Batch Records to Big Production: Controlling Quality at Scale

    Scaling from kilo lab experiments up to dozens of tonnes every month, you face harsh lessons in process control. Our team carefully tracks the consumption of each raw material, especially the routes of butylation and methylation, aware that a slight impurity or incomplete reaction can shift the entire batch out of spec. Quality control teams on the floor track parameters like residual unreacted phenols and esters, using gas and liquid chromatography methods honed over years.

    Environmental factors also matter. We adhere not just to industry best practices but to practical, lived knowledge. Spills or vapor release events not only pose compliance problems—they lead to wasted batches, higher costs, and challenging clean-up activities. Our team’s hands-on knowledge means that process temperatures, solvent handling, vacuum levels, and filtration are monitored shift-to-shift, with traceability in every record. Long-term relationships with suppliers ensure raw materials meet our own requirements before they even hit our reactors.

    Unexpected shutdowns can knock an entire production calendar off-balance. We run regular checks on heat exchangers, checking for fouling or nitrate build-up from cooling water. If a reactor needs quick repairs, our maintenance crew doesn’t just wait—they use knowledge built from years of frequent preventative maintenance, knowing exactly which valves or gaskets might threaten to leak or corrode when exposed to organic solvents. This makes a difference in overall product reliability that customers notice every quarter.

    Real-World Feedback: What Our Customers Teach Us

    Our history with Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate hasn’t just been about process improvement behind closed doors. We value every complaint, suggestion, and field report we receive. One polymer extrusion operation flagged an issue with lumping during humid summer storage. Based on this, our team worked to produce a flow-improved grade, introducing silica treatments and adjusting drying parameters to combat caking. The result, after thorough shipping trials, saved our customer countless hours in cleaning hoppers and stabilizer feeders.

    Another partner, working in high-performance automotive coatings, challenged us to meet a stricter color index. They wanted a product that left no yellow trace even at higher loading levels and under prolonged UV exposure. By reviewing our batch histories and refining wash steps, we managed to drop color formation. These changes, documented in both in-house and customer benchmarks, let them push their coatings into more demanding applications.

    We’ve learned from high-throughput compounding lines that poorly handled stabilizer powders can end up wasted, especially at loading points. Simple steps such as modifying hopper designs, introducing multi-stage sieving, or running antistatic controls led to immediate reductions in raw material loss. We share these lessons directly with customers during startup phases, offering on-site troubleshooting, not just standardized advice.

    Why Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate Outperforms Alternatives

    Competition in the antioxidant market brings up questions about price, performance, and compatibility. Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate stands out from clear-cut phenols by showing far greater resistance to volatilization. Where BHT (Butylated Hydroxytoluene) or simple butylated benzoates start losing efficiency in high-temperature or vacuum processing, our ester compound continues to protect finished goods without drifting off or breaking down.

    This antioxidant doesn’t just keep polymer chains safe during manufacture; it holds on during the storage and transport of semi-finished and finished goods. Our experience in packaging and shipping has shown the ester’s low reactivity with common stabilizer carriers. There’s little risk of early crosslinking, yellowing, or deposit build-up that frustrates many processors who use less robust molecules.

    Other stabilizers, especially those with lower molecular weights, often migrate more quickly in food-contact or medical-grade plastics, triggering compliance issues. We frequently hear from regulatory compliance officers and QA managers who praise the consistent low-extractable profile of our product grades. High-purity Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate offers confidence when facing international audits or certification renewals.

    Several additive blends in the market try to combine convenience with savings. Yet, in high-performance applications, heating cycles, or aggressive blends—including flame retardants or heat stabilizers—some competitors’ products don’t hold up past a few regeneration cycles or environmental simulation runs. Our compound’s thermal and oxidative stability, proven by repeated testing, means less rework, higher yield, and lower unplanned downtime for clients scaling up ambitious projects.

    Our Commitment to Safe and Sustainable Production

    Producing chemicals carries major responsibilities, both for our employees and the environment. We've invested in dust-control and solvent-recovery systems specifically designed for products like Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate. These systems didn’t arrive overnight—they stem from years of finding bottlenecks in old ductwork, monitoring solvent vents, and adapting to ever-tightening local regulations.

    Safe handling procedures grow out of feedback loops established between the plant, lab, and warehouse. Before shipping out, we thoroughly vet packaging solutions to make sure our product arrives without loss or degradation from exposure to light, moisture, or oxygen. Our logistics team coordinates both standard and customized deliveries, sometimes offering nitrogen-packed bags or lined drums to shield the antioxidant from aging in transit.

    We understand the value of reliable supply, so ongoing investments in utility backup, staff training, and risk management directly contribute to the resilience our production schedule reflects. Our neighbors, local authorities, and partners recognize this commitment because we prioritize transparency and continual improvement, not just compliance checkboxes.

    Supporting Research and Backing New Applications

    Higher performance in resin and coating industries means end-users constantly push the limits for weather resistance, clarity, and mechanical properties. We don’t just wait for requests. Our laboratory teams collaborate closely with academic and industrial partners who seek to understand the molecular dynamics that allow Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate to outperform classic antioxidants.

    Our technical support team shares real, actionable advice based on batch histories and application studies. A recent collaboration with a medical device component maker resulted in process tweaks that sharply reduced product rejection rates. By identifying how tiny residuals impacted biocompatibility, we helped raise passing rates and ensured compliance with strict health standards.

    Emerging uses, from advanced 3D printing filaments to novel adhesive blends, bring fresh challenges. Each demand for higher transparency, longer operational lifetimes, or faster production cycles feeds back into our own R&D projects. Our feedback cycle involves direct conversations with engineers, line operators, and lab techs. Their insights tighten our process and push us to anticipate next-generation requirements.

    Comparing Across Applications: Making the Right Choice

    Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate may not be the answer for every industry, but it consistently earns high marks where high temperatures, oxidative stress, or material clarity come into play. Polyolefins, polyesters, and specialized coatings all show better retention of color and physical properties with this stabilizer, based on thousands of production trials and customer case studies.

    When plastics undergo multiple heat-cool cycles—think about recycling streams or engineering compounds—the need for a non-migratory, thermally robust antioxidant shows up fast. We’ve tracked performance across different polymers, noting especially strong results in systems where alternative stabilizers led to early degradation. Examples include cables, fibers, clear film, and automotive interiors. Competitors’ data often highlight theoretical performance, but our feedback comes straight from extrusion lines and field failure analysis.

    For those seeking durable, light-resistant plastic components or coatings, avoiding yellowing is a daily battle. Our field data, gathered from continuous outdoor exposure and artificial aging chambers, supports the superiority of our ester antioxidant. The differences become obvious in tough conditions, where UV, oxygen, and heat combine. Many of our long-term partners who once switched between different solutions now rely on this product for batch-to-batch reliability and fewer technical complaints from end customers.

    Investing in Continuous Improvement: Listening, Adapting, and Leading

    Every year, new challenges emerge. Sometimes it’s a new regulatory directive, sometimes it’s a supply chain hiccup, and occasionally it’s a production innovation that trims cycle times in half. As a manufacturer, sitting still isn’t an option. With Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate, our philosophy has remained unchanged: use field realities and scientific rigor to drive improvements, not theoretical models.

    We engage with universities, research consortia, and clients who examine molecular performance at the edge of what’s possible. Their requests led us to automate monitoring at every major process step, investing in digital tracking for each lot shipped. Safety audits are not just self-checks; they bring fresh sets of eyes to keep our process honest and spot improvement opportunities before problems arise.

    Recent investments in analytical methods, including rapid residue detection and high-accuracy particle analysis, help identify and correct process drift faster than ever before. These tools allow our operators to catch trends, correct deviations, and minimize waste while boosting product consistency.

    Partnering With Those Who Challenge Us

    Our manufacturing journey with Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate has been shaped by more than just internal know-how. Each new customer brings unique system needs, from melt-flow control to stringent regulatory requirements. Hearing about a customer’s unforeseen mixing problem, a sudden equipment failure, or color drift mid-batch keeps our technical and customer service teams on their toes.

    User experience often pushes us to deliver more than bulk material. We develop application guides, share best practices for blending and compounding, and—when appropriate—send process engineers and chemists to troubleshoot on-site. Over the years, on-the-ground advice has led many users to optimize stabilizer usage, reduce scrap, and improve final product appearances. The learning keeps flowing both ways; sometimes the customer’s tweaks inspire our next process review.

    We keep records of these collaborations, using lessons learned to steer our continuous improvement meetings. This cycle of feedback, improvement, and transparency strengthens our relationships and continually evolves our product.

    Meeting Higher Standards in Global Markets

    With supply going to customers worldwide, we face a patchwork of compliance rules, performance criteria, and reporting needs. It’s not just about meeting today’s regulations; it’s about anticipating tomorrow’s. Our compliance team works closely with certification bodies, monitors trends in migration limits, and stays aware of new product labeling protocols around the world.

    We commit to providing transparency in testing, documentation, and origin. Forward-thinking clients demand not just technical data, but evidence of responsible sourcing and product stewardship at every step. Years of working alongside demanding auditors prepared us to provide detailed production histories, validated analysis results, and robust change notification procedures. Trust builds from this level of openness, especially as markets grow more complex.

    Improvements in process safety, emissions control, and waste management not only avoid fines—they build stronger partnerships and a healthier work environment. Our insistence on incremental progress came from years of scrubbing floors, running trial-and-error maintenance routines, and being held accountable by regulatory bodies who expect better each inspection cycle.

    Looking Ahead: Innovation, Collaboration, and Responsibility

    We treat the manufacture of Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate as a constantly moving target. Even small process gains multiply out across thousands of tons and hundreds of customers. Our work stands as much on the chemistry as on our willingness to listen and adapt.

    A future with more sustainable polymers, more demanding application profiles, and greater transparency in material sourcing pushes us to raise our own standards. We continue to welcome challenges, design safer and cleaner processes, and invest in technology and people. Shared insights move our operation forward, strengthened by every voice in our supply chain.

    Methyl 3,5-Di-Tert-Butyl-4-Hydroxybenzoate’s ongoing relevance in demanding fields like advanced polymers, durable coatings, and specialty compounds shows how trusted experience and close collaboration across manufacturer and end user can keep a product at the forefront—year after year, shift after shift.