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Methyl 2-Methylbutyrate

    • Product Name Methyl 2-Methylbutyrate
    • Alias isopentanoic acid methyl ester
    • Einecs 210-251-1
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    152581

    Chemical Name Methyl 2-Methylbutyrate
    Cas Number 868-57-5
    Molecular Formula C6H12O2
    Molecular Weight 116.16 g/mol
    Appearance Colorless liquid
    Odor Fruity, apple-like
    Boiling Point 108-109 °C
    Density 0.876 g/mL at 25 °C
    Refractive Index 1.400–1.404 at 20 °C
    Flash Point 20 °C (68 °F)
    Solubility In Water Slightly soluble
    Pubchem Cid 12368

    As an accredited Methyl 2-Methylbutyrate factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Clear glass bottle, 100 mL, sealed with a screw cap. White label displays chemical name, hazard symbols, and safety information.
    Shipping Methyl 2-Methylbutyrate should be shipped in tightly sealed, chemical-resistant containers under cool, ventilated conditions. It is classified as a flammable liquid and must be handled according to relevant regulations, with appropriate hazard labeling. Avoid heat, sparks, and open flames during transport, and comply with local and international shipping requirements for hazardous materials.
    Storage Methyl 2-Methylbutyrate should be stored in a tightly closed container in a cool, dry, well-ventilated area away from sources of ignition, heat, and direct sunlight. Keep it away from incompatible substances such as strong oxidizing agents and acids. Store at room temperature and ensure proper labeling. Use appropriate secondary containment to prevent leaks or spills.
    Application of Methyl 2-Methylbutyrate

    Applications of Methyl 2-Methylbutyrate in Industrial Manufacturing

    As the direct manufacturer of Methyl 2-Methylbutyrate, we support precise applications across specialized downstream sectors. Our material’s unique ester character enables impactful formulation roles in select fragrance, flavor, and specialty solvent markets. Each scenario below details specific industry standards, addition ratios, how the chemical is incorporated in process flows, and the intended final product formats, ensuring practical guidance based on actual customer requirements.

    1. Food & Beverage Flavorings (Synthetic Fruit Flavor Production)

    Methyl 2-Methylbutyrate serves as a key ingredient in formulating synthetic fruit flavors, thanks to its distinctive apple-like and fruity aroma profile. Food-grade applications require strict compliance with limiting thresholds and allergen declarations. The raw ester is dosed during the compounding of concentrated flavor bases at adjusted levels depending on the intensity needed for juice drinks, confectionery, or dairy analogs. The substance supports flavorists targeting green apple, pineapple, or strawberry notes, and must be registered in ingredient lists where relevant according to local labeling codes.

    Industry compliance standards

    • U.S. FDA 21 CFR Part 172.515 (Flavoring Substances and Adjuvants)
    • EU Regulation (EC) No 1334/2008 (Flavourings and Certain Food Ingredients with Flavouring Properties)
    • JECFA Generally Recognized as Safe (GRAS) listing
    • GB 2760 (China National Food Safety Standard for Food Additive Use)

    Typical usage ratio

    • 0.1–100 ppm in finished beverage and confectionery bases; adjusted by sensory evaluation protocols and regulatory maximums

    Downstream process integration

    • Directly blended into aqueous or alcohol-based flavor concentrates during batch compounding, prior to final dilution and quality control flavor profiling

    Final product types

    • Fruit-flavored soft drinks
    • Chewing gums
    • Candy mixes
    • Bakery fillings and fruit spreads

    2. Fine Fragrance Compounding (Perfume and Toiletry Formulation)

    Within fragrance houses, this ester is incorporated into the headspace of layered scent compositions to impart sharp, fresh top notes. Its volatility and compatibility with a broad ester suite allow for nuanced performance in both alcohol-based and water-based perfumes. Firms integrate it fully during controlled mixing of concentrate oils, followed by maceration and filtration to achieve regulatory-compliant solubilization before bottling. Multiple international and regional standards guide its declaration and permitted use, as well as purity testing and allergen management.

    Industry compliance standards

    • IFRA (International Fragrance Association) Standards (current amendment)
    • EU Cosmetics Regulation (EC) No 1223/2009
    • REACH Registration (EC 1907/2006)
    • California Safe Cosmetics Act for U.S. market

    Typical usage ratio

    • 0.05–3% of total fragrance oil concentrate; level determined by olfactory impact, IFRA limits, and end-product market regulations

    Downstream process integration

    • Added to fragrance oil during primary concentrate mixing, followed by stabilization and alcohol dilution for perfumes or detergent solubilization for personal care formats

    Final product types

    • Eau de toilette and Eau de parfum sprays
    • Liquid soaps with fruit accords
    • Shower gels and bath foams with green top notes
    • Air freshener blends for home or auto

    3. Tobacco Industry (Cigarette and Cigar Flavor Additives)

    Tobacco processors utilize this ester in low-dose flavor treatments for modifying sensory profiles of reconstituted or blended leaves. Its fruity note harmonizes with both natural and synthetic flavoring systems used in cigarette, cigarillo, and pipe tobacco lines. Compliance with regionally variable threshold standards and toxicological screening is enforced, including special registration for Reduced Risk Products. The compound enters as a minor additive in aqueous spray or casing solutions and is distributed uniformly via drum or rotary atomization onto lamina sheets prior to drying and final blending.

    Industry compliance standards

    • U.S. FDA Premarket Tobacco Product Application (PMTA) flavor additive review
    • EU Tobacco Product Directive 2014/40/EU—Annex II (Additive Regulation)
    • China Tobacco Additive Catalog (STMA approval)
    • SGS/ISO 17025 analytical compliance for trace residuals

    Typical usage ratio

    • 2–100 ppm of total tobacco formulation; dosage scaled per batch sensory panel feedback and regulatory risk assessments

    Downstream process integration

    • Incorporated into flavorant casing solution mixed and sprayed directly onto shredded or sheet-form tobacco, followed by low-heat drying and conditioning

    Final product types

    • Flavored cigarettes and cigarillos
    • Pipe tobacco blends
    • Reduced-risk heat-not-burn tobacco sticks
    • Roll-your-own shisha mixtures

    4. Industrial Solvents for Analytical and Extraction Procedures

    This ester demonstrates high efficiency as a specialty extraction and carrier solvent for certain GC reference standards, flavor headspace analysis, and targeted botanical extraction protocols. Laboratories and extraction facilities select it for its moderate polarity, low miscibility with water, and clean evaporation with minimal residue. Prior to application, all solvent batches undergo GC and purity checks according to laboratory-grade protocols. It is generally introduced during sample preparation steps or as a medium for dissolving volatile organics; cleaning validation and residue threshold conformity are strictly monitored.

    Industry compliance standards

    • ASTM D1353 for Purity of Organic Solvents
    • ICH Q3C (Impurities: Residual Solvents Guidelines)
    • USP/NF General Chapter <467> Residual Solvents
    • ISO/IEC 17025 for Analytical Laboratory Competency

    Typical usage ratio

    • Varies by end-use: 1–20% in extraction mixtures; 10–200 μL per analytical sample; specific levels based on extraction/load requirements and solvent recovery rate

    Downstream process integration

    • Used as a direct solvent for analyte dissolution, extraction from botanical matrices, or as an internal standard in GC sample prep; evaporated or recovered post-process

    Final product types

    • GC/MS laboratory standards and calibration mixtures
    • Isolates and pure botanical extracts for research
    • High-purity analytical reference standards
    • Processed natural flavors post-extraction
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    Certification & Compliance
    More Introduction

    Methyl 2-Methylbutyrate: Product Insights from the Manufacturer’s Floor

    The Character of Methyl 2-Methylbutyrate

    In our years of production, we have found that Methyl 2-Methylbutyrate stands out among specialty esters for its distinct fruity aroma and robust formula. This clear, colorless liquid comes from a precise reaction between 2-methylbutyric acid and methanol, and the result draws consistent interest from perfumery, food flavoring, and specialty solvent sectors. On our shop floor, teams always emphasize purity and batch consistency because both drive product performance. The molecular formula is C6H12O2, with a molecular weight of 116.16. We typically deliver it with a minimum purity of 99%. Each batch passes GC analysis before moving to our warehouse, and our tanks are nitrogen-blanketed to prevent oxidation during storage.

    Distinctive Traits from a Manufacturer's Standpoint

    Colleagues in flavor and fragrance industries come to us for Methyl 2-Methylbutyrate because they need lots, sometimes hundreds of kilograms at a time, without risk of unwanted notes showing up in their blends. It brings a clean, sweet, fruity odor—think apple, pineapple, or cherry nuances—while many other esters bring stronger or rougher top notes. When you open a drum, you notice how little off-odor or discoloration turns up. This makes a difference. Product purity and a controlled water content (less than 0.2%) prevent sour edges or powdery off-characters from developing, even after months of storage.

    Compared to related esters like methyl butyrate or ethyl isobutyrate, our methyl 2-methylbutyrate clocks a higher odor threshold and brings softer, rounder characteristics. In applications like hard candy and beverage flavoring, this allows formulators to layer flavors without overwhelming the base. These small differences matter. Downtimes from contamination or reprocessing cost more than up-front checks and raw material tracking. We’ve learned this the hard way over years of filling flavor houses’ special orders and trouble-shooting misblended batches—they’re never the same when the wrong ester slips in.

    Adapting Specifications for Industry Use

    On our presses, Methyl 2-Methylbutyrate batches must meet a narrow window on specifications. We set GC-assayed purity above 99%, keep total acidity low, and verify every tank for residual solvents. Low thresholds for impurities like methanol or non-esterified acids keep flavors mild and fragrances predictable. The standard gravity falls around 0.87–0.89 g/cm3 at 20°C, and we track this as proof of minimal batch-to-batch drift. Water content stays below 0.2%. Applications in aromas—gummies, jams, soft drinks—see real impact from these details. Once, a customer flagged a slight plastic note that traced back to a leaky pump head introducing minute silicone traces. Now, we audit valves twice per shift and swap out soft seals for food-grade lines, just to safeguard the natural character.

    Down our production line, temperature swings and slow transfers challenge the stability of volatile esters like this one. Ambient humidity can pull in stray water, leading to batch rejection. Our solution has been an integrated drying and closed-tank transfer system that cuts exposure at every step. Operators document incidents within 15 minutes, so retracing faults is direct, and corrective action is quick. These habits formed out of necessity—customers don’t tolerate unexplained batch variance.

    Practical Applications Seen in Our Own Orders

    Most volume heads to food and beverage formulators and fragrance houses. The reason they return is simple: their buyers have sharp noses, and the finished product either meets the standard or it doesn't. Flavored candies and drinks form a huge share of demand because the ester delivers punchy, warm fruit notes at low dosing levels, saving cost and reducing risk of overpowering sweetness. In the laboratory, just a part per million can brighten a dull apple or strawberry base. We’ve seen leading gum makers standardize on our material after tests with inferior substitutes led to shelf-life complaints and flavor drift.

    Perfumery workers value this ester because it blends smoothly without dominating the profile. It bridges top and heart notes, and lacks the harsh, sharp attack that other small esters present. Artisan candle and soap makers take bulk orders when they want reliability batch after batch; they get the same aroma profile in cool and hot throw tests. Key global flavor and fragrance houses have told us that even small impurity swings make their entire blend out of spec. Once, a partner’s blend failed regional audits and cost them export. That drives home the importance of tight process control.

    Pharmaceutical labs sometimes draw from our inventory as well. They require the ester as an intermediate or a starting material in synthesizing specialty molecules, requesting certificates covering odorous impurities, residual solvents, and allergen information. Meeting their demands involves more documentation, careful lot tracking, and extra washing of plant equipment to preclude any memory effect from previous runs.

    Safety, Handling, and Environmental Considerations

    Handling Methyl 2-Methylbutyrate safely takes more than gloves and goggles, despite its pleasant aroma. Vapors creep invisibly and can catch fire under the right conditions. Over the past few years, we have upgraded our transfer systems with sealed, grounded lines and double-checked ventilation to keep vapor concentrations below safe limits. Our workers get refresher training—not because it’s required, but because one simple mistake can lead to an accident.

    We use stainless steel drums or HDPE containers specific to this ester. Leeching from substandard plastic results in yellowing or off odors, so every delivery comes in new or thoroughly refurbished packaging. If operators spot a fuzzy headspace odor, the entire batch gets quarantined. Vent line sensors and spill containment are routine, and we audit compliance after every shift. Fire marshals have signed off on our updated protocols several years running, and our insurance underwriters review our spill response every quarter.

    Disposal practices matter to us, and to regulators. Small spills go straight to a carbon bed and then to specialty incineration; rinses and wash-water run through onsite treatment plants that reduce solvent load below discharge standards. We keep solvent records for every lot, which means fewer surprises from audits and product recalls.

    Differences from Other Esters: Manufacturer’s Observations

    The shelf-life for our Methyl 2-Methylbutyrate extends well beyond a year if kept cool and sealed, contrasting with shorter shelf lives for similar esters that hydrolyze or polymerize faster. Over the years, we have benchmarked side by side with Methyl butyrate, Ethyl butyrate, and Methyl isobutyrate and have documented the differences in aroma stability and volatility. Ours holds its profile better under warm or humid storage. This matters especially for customers in Asia and South America, who sometimes store entire seasons’ supply in facilities without climate control.

    Other esters with similar molecular size skew either sweeter or less stable. For example, methyl butyrate gives a more intense, piercing pineapple note that becomes cloying at high doses. Methyl 2-Methylbutyrate builds flavor with more subtlety, giving room for midrange and background notes. That’s why cologne and beverage makers prefer it for multi-layered compositions. In side-by-side stability trials, we also logged less phase separation and color change, even after sunlight exposure. Our technical team published these results in trade journals, and this has helped formulators in large consumer goods companies minimize risk across their seasonal flavor launches.

    Challenges and Solutions from Decades of Experience

    One ongoing challenge remains: sourcing high-purity 2-methylbutyric acid, which makes or breaks final ester quality. Global supply chains for organic acids show volatility, with swings in purity and trace contamination. We buy acid in large volumes from vetted sources, test them in our own QC lab, and will cancel shipments if batches fail odor or impurity benchmarks. Production can slow down, but we avoid costly downstream issues. There isn’t a shortcut—starting material controls the result, and re-distilling off-grade raw acid rarely delivers the original odor profile.

    Another past pain point involved waste handling for spent wash solvent. We redesigned the recover/recycle loops on our plants, cutting annual hazardous waste volumes by over 40%. The economics improved—less waste hauling, and more solvent available for blending future batches. This took capital investment (new tanks, process controls, operator training) but paid off: minimizing batch rejection, controlling emissions, and strengthening customer trust.

    Years ago, one batch suffered a mysterious rise in acidity, traced to a leaky reactor seal. Our maintenance crew found and swapped the fault in less than two days, but the incident pushed us to build a predictive maintenance dashboard that keeps tabs on temp, pressure, seal status, and vibration in real time. Since implementation, minor leaks catch attention before affecting product. These investments become habits, and they shape how we meet both internal and customer standards going forward.

    Constant Vigilance, Continuous Improvement

    Every drum and tote of Methyl 2-Methylbutyrate leaving our facility carries the history of a hands-on approach—raw material testing, batch checks, routine equipment audits, and a real-world responsiveness to customer needs. No batch leaves without full COA and material traceability. Our technical staff members take pride in walking production lines, talking with operators, and recalibrating equipment if even a subtle note steps outside target.

    The access to real feedback from flavor chemists, perfumers, and food scientists means problems never stay hidden long. Our relationships with industry partners go beyond contract terms—they fuel process updates, new quality benchmarks, and product improvements. Once, a major beverage brand’s R&D flagged a thermal stability issue we hadn’t seen. In response, we built a round of accelerated aging trials, exposing new and old samples to cycling heat and humidity. The insight eliminated a shelf-life roadblock and opened up wider usage in tropical markets.

    Sharing Experience Openly

    Our doors have always remained open to auditors from flavor houses, regulatory inspectors, and independent consultants. We keep process records, regulatory filings, and analytical histories on site. New regulatory pressures—from allergen labeling to clean label initiatives—have forced changes in raw mat sourcing and batch lot segregation, but each challenge has sharpened our expertise. When incoming requests spark an idea for better handling, less energy use, or deeper solvent recovery, we run pilot trials and welcome visitors to see results firsthand.

    This hands-on scrutiny has shaped production. For example, with rising demand for non-GMO and allergen-free food flavoring, we source starting materials from suppliers with precise documentation. Each lot is checked for residual protein markers and adventitious contamination. Instead of waiting for complaints, we solicit samples from high-sensitivity labs to validate each tweak. Our philosophy isn’t about checking regulatory boxes; it’s about minimizing risk for our partners, who trust the outcome in their finished goods.

    Looking to the Future: Trends Affecting Methyl 2-Methylbutyrate

    The landscape for specialty esters changes rapidly—shifts in flavor trends, natural ingredient sourcing, tighter emissions control, and sustainability reports shape demand and supply. As beverage and food categories press for natural origin claims, the debate turns on whether chemical-process esters compete with “extract-derived” alternatives. Natural extraction methods come with sky-high costs and inconsistent supply; synthetic routes, managed well, offer predictability, consistent quality, and cost control. Both paths have strengths. Our team investigates ways to derive precursor acids from fermentation rather than petrochemical supply, making real headway into sustainable production without losing product performance.

    Our technical staff also contribute to industry roundtables and codevelop benchmarks for process waste reduction and solvent life-cycle reporting. Sharing analytical findings—like those documenting improved shelf-life after raw material upgrades—helps partners across the supply chain lift their quality. If issues arise, like off-spec odor in a customer’s facility, we respond with on-site visits and deeper analysis, not boilerplate apologies or generic troubleshooting. We view every customer claim as a learning opportunity.

    Customer Relationships Built on Expertise, Not just Product

    Fielding questions about how Methyl 2-Methylbutyrate stacks up against alternatives never feels routine. Buyers have to trust that our product won’t interfere with their own quality systems; the stakes for multibillion-dollar brands or boutique fragrance launches run equally high. The difference becomes clearer each time a partner relies on us for rush resupply, asks for custom analysis, or faces a tricky regulatory question and gets technical documentation straight from process engineers.

    Open sharing, regular site visits, and candid troubleshooting set our team apart from commodity resellers and brokers. Years in the industry taught us that honest feedback (even when uncomfortable) drives long-term trust. We keep specialists in analytical chemistry, materials handling, and food law on site, so feedback routes directly from customer query to corrective action. Every improvement in plant practice, waste reduction, or test method reflects a lesson learned from real-world application.

    Commitment to Constant Progress

    Methyl 2-Methylbutyrate production’s success relies on vigilance in process, investment in training, and partnership with demanding users. Results matter—in the drum, in the blend, and ultimately in the hands of the consuming public. We don’t cut corners; each specification reflects years of lessons learned both from lab trials and unexpected real-world scenarios.

    Change never stops—flavor trends, regulations, and supply chain priorities keep evolving. Our work centers on continuous improvement: smarter sourcing, deeper process controls, cleaner waste management, and lasting customer relationships. Every drop of Methyl 2-Methylbutyrate shipped from our facility carries a story of hands-on experience, direct accountability, and the ongoing drive to deliver performance batch after batch. It’s a commitment shaped by our pride as manufacturers, dedicated to earning—and keeping—the trust of partners around the globe.