Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing admin@sinochem-nanjing.com 3389378665@qq.com
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(+)-Menthol

    • Product Name (+)-Menthol
    • Alias Peppermint camphor
    • Einecs 212-193-2
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    525614

    Chemical Name (+)-Menthol
    Cas Number 2216-51-5
    Molecular Formula C10H20O
    Molecular Weight 156.27 g/mol
    Appearance colorless crystals
    Melting Point 42-45 °C
    Boiling Point 212 °C
    Density 0.890 g/cm3
    Optical Rotation [α]D20 = +49° (neat)
    Solubility In Water slightly soluble
    Flash Point 93 °C
    Pubchem Cid 1254

    As an accredited (+)-Menthol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing (+)-Menthol is packaged in a 100g amber glass bottle with a screw cap, labeled with hazard warnings, purity, and CAS number.
    Shipping (+)-Menthol is shipped in tightly sealed containers to prevent contamination and volatilization. It is transported as a solid or liquid, depending on temperature, and should be stored in a cool, dry, and well-ventilated area, away from heat sources and incompatible substances. Shipping complies with relevant hazardous material regulations.
    Storage (+)-Menthol should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from sources of ignition and incompatible substances such as strong oxidizing agents. The storage area should be free from moisture and direct sunlight. Label the container clearly, and ensure it is kept at room temperature to maintain the compound’s stability and prevent degradation.
    Application of (+)-Menthol

    Applications of (+)-Menthol in Industrial Manufacturing

    As a direct manufacturer of (+)-Menthol, we supply to a range of industrial sectors where precise formulation, strict compliance, and established downstream processes dictate real-world application. Below, we detail key industrial use cases based on end-market production requirements.

    1. Pharmaceutical Formulations: Topical Analgesic Ointments and Creams

    Major pharmaceutical manufacturers use (+)-Menthol as an active ingredient in topical analgesic products for pain relief, often in combination with methyl salicylate or camphor. Production lines require consistent menthol melting and dispersion at controlled temperatures to ensure batch-to-batch uniformity. Producers must meet strict pharmacopoeial standards to obtain finished forms such as gels, creams, and rub-on sticks for both OTC and prescription use.

    Industry compliance standards

    • United States Pharmacopeia (USP)
    • European Pharmacopoeia (Ph. Eur.)
    • Good Manufacturing Practice (GMP) (ICH Q7)
    • FDA 21 CFR 310.545 (External Analgesic Monograph)

    Typical usage ratio

    • 1.25%–10% by weight depending on analgesic class and geographic regulatory requirements. Lower concentrations (1.25–2%) in combination products; higher concentrations (up to 10%) permitted for localized effect, subject to product labeling restrictions.

    Downstream process integration

    • Dosed in melting vessels prior to the emulsification step. Homogenized after active ingredient verification to ensure physicochemical stability and accurate distribution in final matrix.

    Final product types

    • Pain relief creams
    • Arthritis gels
    • Muscle rubs
    • Medicated patches

    2. Oral Care Manufacturing: Toothpaste and Mouthwash

    Toothpaste and oral rinse producers routinely formulate with (+)-Menthol to provide both flavor and a cooling sensation. Precision dosing and blending during the flavor addition stage ensures desired taste profile and regulatory limits. The material must be food/medicinal grade and free of contaminants for use in oral-contact goods exported worldwide.

    Industry compliance standards

    • Food Chemicals Codex (FCC)
    • ISO 11609:2017 (Dentifrices — Toothpastes)
    • FDA 21 CFR 172.515 (Flavoring substances, USA)
    • SFDA National Food Safety Standard (GB 2760-2014, China)

    Typical usage ratio

    • 0.1%–2% by weight in paste; 0.03%–0.1% in liquid rinses. Ratio adjusted based on target market flavor intensity and combination with other flavoring agents.

    Downstream process integration

    • Added during batch flavoring stage in heated mixing tanks. Incorporated after base preparation but before final homogenization, ensuring uniform dispersion in finished tubes or bottles.

    Final product types

    • Fluoridated toothpaste
    • Whitening paste
    • Antiseptic mouthwash
    • Children’s toothpaste

    3. Food Flavor Industry: Chewing Gum and Confectionery

    Food processing plants incorporate (+)-Menthol in sugar and sugar-free chewing gum, hard and soft candies, and other confectionery for both taste and functional cooling effects. Product safety and traceability require adherence to food additive regulations and HACCP-compliant processes to control risk of cross-contamination.

    Industry compliance standards

    • Codex Alimentarius (FAO/WHO)
    • JECFA food additive evaluation (INS 423)
    • Food Safety Modernization Act (FSMA)
    • EFSA food additive specifications (EU Regulation 1333/2008)

    Typical usage ratio

    • 0.05%–0.25% in gum base and confectionery. Adjusted to flavor strength, sweetness profile, and regional taste trends; higher concentrations may trigger labeling as “extra strong.”

    Downstream process integration

    • Incorporated during ingredient blending prior to extrusion, molding, or deposition. Added after thermal phase to avoid menthol volatilization and loss of aroma intensity.

    Final product types

    • Sugar-free chewing gum
    • Mint hard candies
    • Filled chocolates
    • Breath strips

    4. Tobacco Product Manufacturing: Cigarettes and Reduced-Risk Products

    Industry leaders in tobacco products incorporate (+)-Menthol in filter tips, cigarette blends, and heated tobacco sticks to deliver cooling taste and mask harsh tobacco notes. Dosage incorporates compliance with market-specific regulatory maximums. Manufacturers require traceability from raw material receipt through flavor casing and blending operations, using controlled environments to minimize menthol loss during packing and storage.

    Industry compliance standards

    • US FDA Tobacco Control Act (21 CFR Part 1140)
    • EU Tobacco Products Directive (2014/40/EU)
    • GMP for Food and Tobacco (ISO 22000)
    • China National Standard for Cigarettes (GB 5606)

    Typical usage ratio

    • 0.02%–0.5% by weight in tobacco blend or filter tip. Ratio determined by desired cooling effect, market legislation, and product target (e.g., regular vs. capsule/filter design).

    Downstream process integration

    • Sprayed or dripped onto tobacco blend during flavoring/casing stage, or micro-encapsulated and inserted in filter rods pre-assembly. Sensitive handling to avoid evaporative losses during high-speed processing.

    Final product types

    • Menthol cigarettes
    • Heated tobacco sticks
    • Filter capsules
    • Moist snuff, snus

    5. Personal Care Manufacturing: Shower Gels and Shampoos

    Global personal care brands formulate with (+)-Menthol to provide a refreshing effect in shower gels and scalp care shampoos. Batch production involves solubilizing and stabilizing menthol with co-solvents or surfactant bases, preventing recrystallization and ensuring a transparent or homogenous end product. Material traceability and microbiological controls are critical for cosmetic GMP compliance and retail release in international markets.

    Industry compliance standards

    • ISO 22716 (Cosmetics GMP)
    • EU Cosmetic Regulation (EC) No. 1223/2009
    • FDA Voluntary Cosmetic Registration Program (VCRP)
    • ASEAN Cosmetic Directive

    Typical usage ratio

    • 0.05%–0.3% in rinse-off products. Dosed higher for men’s intensive formulas and lower for family/general use. Adjusted based on combined fragrance and claimed “cooling” strength.

    Downstream process integration

    • Dissolved with solvents (propylene glycol or PEG) prior to surfactant addition. Incorporated in cold or warm mixing step after pH adjustment and bulk ingredient blending.

    Final product types

    • Refreshing shower gel
    • Scalp care shampoos
    • After-sport body wash
    • Cooling foot soaks

    6. Veterinary Pharmaceuticals: Animal Liniments and Sprays

    Manufacturers of veterinary preparations use (+)-Menthol as a topical counter-irritant and cooling agent in liniments, gels, and sprays for equine and livestock care. Strict compliance with veterinary medicinal standards and animal-use labeling applies. Ingredient enters blending and milling stages under temperature-controlled protocols to preserve activity and control odor intensity in sensitive animals.

    Industry compliance standards

    • European Medicines Agency (EMA) Veterinary Medicinal Products Regulation (EU 2019/6)
    • US FDA Center for Veterinary Medicine (CVM) guidance
    • British Pharmacopoeia: Veterinary Medicines
    • VICH GL9 Good Manufacturing Practice (GMP) for APIs

    Typical usage ratio

    • 1%–5% in topical veterinary formulations. Higher end for concentrated sprays/liniments permitted with appropriate labeling for animal tolerance and residue limits.

    Downstream process integration

    • Added after main vehicle foundation in agitated tanks, typically blended with carrier oils or alcohols before thickening, bottled using GMP-compliant filling lines to preserve antimicrobial properties and prevent cross-contamination.

    Final product types

    • Equine liniment
    • Cattle cooling gel
    • Udder sprays
    • Poultry leg balms
    Free Quote

    Competitive (+)-Menthol prices that fit your budget—flexible terms and customized quotes for every order.

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    Certification & Compliance
    More Introduction

    Introducing (+)-Menthol: Pure Consistency from the Factory Floor

    What Sets (+)-Menthol Apart in Today’s Market

    Every crate of (+)-Menthol leaving our facility represents years of hands-on manufacturing experience, trial, precision, and the steady attention of chemists whose work shapes the supply chain far beyond our own doors. Unlike racemic menthol you can find produced by quick syntheses, our (+)-Menthol stands as the levorotatory, naturally-occurring isomer. We have focused our resources, staff training, and process improvements exclusively on guaranteeing a consistent optical rotation and melting range. Analytical results taken from every batch show our usual range of +49° to +51° (measured in ethanol, as outlined in standard pharmacopeia), with a melting point tight around 42°C.

    Reaching this level has taken challenging the typical separation process. We made decisions on distillation columns, substrate solvent quality, and filtration grades not simply for compliance, but to push purity above the threshold. From our vantage point, purified menthol is not just a white crystalline solid—it is a foundation that defines the aroma, freshness, and stability in finished applications.

    Usage Based on Decades of Market Demand

    Menthol surrounds most of our daily senses—from the toothpaste in the bathroom to the topical ointments kept in family cabinets, and sometimes in the air of a confectionery workshop. Over time, our manufacturing team has learned that it is not enough to deliver purity alone. Our menthol powder emulsifies without clumping in alcohol-based and water-based solutions, producing clear results with no granular residue. The flake form, more popular among tobacco blenders and some food flavorists, dissolves quickly in non-polar mediums and resists caking when stored in standard drums.

    Pharmaceutical formulators expect not just clean purity but highly reliable sensory thresholds. Cough lozenge makers and throat spray developers have zero tolerance for any off-notes, camphoraceous tails, or variances in cooling. We have met these demands by investing in in-house odor evaluation panels and taste threshold analysis—something that only a direct manufacturer with a dedicated QA department can offer. End users in compounded medications, toothpastes, or topical gels rely on the stability data we generate, drawn from our storage and shipping tests that simulate the product’s journey to both tropical and temperate climates.

    Food flavorings and beverage houses purchase in bulk, counting on each batch to blend seamlessly. Having processed thousands of metric tons for flavor clients over the years, we’ve tailored our final drying and sieving systems so that (+)-Menthol behaves consistently in dry blends and syrups. From tea bag enhancement to alcohol-free liqueurs, few ingredients play a role as distinctive or as particular as this stereoisomer.

    Cosmetics and toiletries require a menthol that delivers an instant cooling sensation, not leaving behind grit or haze in gel and cream bases. Even minor deviations in crystal size or water content can mean a failed batch for our customers. Our investments in precision drying ovens and humidity-controlled rooms allow us to offer this reassurance. Bar soap integrators and shampoo engineers often visit our plant to audit the consistency of granule shape and size—only possible at the point of production.

    Smoking and tobacco companies continue to use (+)-Menthol not only for its distinct sensory qualities but because regulatory agencies demand documentation on origin, chiral purity, and absence of off-odors or taints. Full supply chain transparency links every kilogram to its original batch and farm sources. All data is generated and managed internally by staff who know the reality of international compliance requirements.

    Differences: A Manufacturer’s Perspective

    As a direct manufacturer, the distinctions between different grades and types of menthol are far more than catalog entries—they impact how our partners run their lines, how much yield is lost, and how often rework is needed. We field requests not just for (+)-Menthol, but also for racemic blends, synthetic D/L-menthols, and natural L-menthols isolated from diverse plant sources.

    (+)-Menthol, as delivered by our process, contains an enantiomeric excess exceeding 99%, verified by chiral gas chromatography after every major production run. This particular isomer creates a recognizable cooling profile, favoured among global dental and pharmaceutical brands. It is also less likely to introduce secondary notes common in mixtures or semi-synthesized varieties.

    Compared to completely synthetic menthol—often produced from petrochemical feedstocks—our product starts from natural precursors. The solid-state features of our crystals, including shape, size distribution, and surface morphology, derive from the exact controls we have built into our distillation and crystallization steps. Our team has adjusted the timing of seeding and the selection of solvents to minimize twin crystals and to block the formation of fine dust, which can cause dosing headaches for automated filling systems downstream. Traders and resellers may offer generic menthols, but few recognize how much risk comes from inconsistent solubility, trace solvents, or unpredictable batch-to-batch aroma.

    In practice, flavorists and compounders notice these differences long before they see a specification sheet. Many of our food, beverage, and oral care clients have told us that generic menthols cause batch inconsistencies, clog dispersion systems, or degrade before product shelf life has expired. Through customer feedback sessions, we have been able to link performance gaps back to crystal morphology and residual impurity content. For example, natural L-menthol from botanical distillation can carry over trace essential oils, while lower-quality synthetic menthol sometimes suffers from harsh top notes due to incomplete stereochemical resolution.

    From the very start, our factory team recognized that successful application in pharmaceuticals rests on repeatable analytical performance as much as on regulatory compliance. The risk of contamination, cross-lot variability, or residual solvents cannot be addressed by paperwork alone. Our facility runs far beyond minimum GMP expectations; chromatography, titration, and organoleptic tests form a triad at each checkpoint. This allows us to quickly identify trends or anomalies before shipping. Only years of real world production can build the system needed to answer the dozens of questions brought by customers with their own complex formulations and facilities.

    In fragrance blending, formulators demand menthol that brings clarity to mint accords rather than overpowering sweetness or bitterness. Over much of my career, I’ve seen perfumers come to us after facing performance issues with cheaper material—usually a result of a non-specific separation step or shortcuts during washing and drying. Consistently providing the cooling undertone, without sharp or muddy overtones, speaks to the difference only a direct producer can deliver by refining its process over hundreds of batches.

    Production Challenges and Answers from the Factory Floor

    Menthol manufacture is not just a reaction to consumer demand—it is the answer to problems that laboratories and factories encounter every day. Industrial-scale crystallization brings its own set of issues, many invisible to someone who only handles the end-user form. Scaling up from kilo-lab lots to metric ton runs, we faced everything from solvent recycling bottlenecks to crystal habit variability and filter cake compaction.

    Every staff member on our process team has confronted moments where a subtle change in coolant pressure, a new source of field mint oil, or an uptick in plant humidity threatens the entire output for that week. For example, controlling solvent phase during final separation is crucial to avoid entraining trace impurities. We’ve dedicated time to tuning our centrifugal filtration cycles, swapping out filter cloths, and adjusting feed rates, often learning through shared experience and data trending.

    With export markets in mind, we regularly monitor how our menthol copes with long-haul sea transport. Months in a container can stress even well-prepared crystals, leading to caking, partial melting, or clumping. Our logistics and technical teams collaborate on packaging solutions—vacuum-sealed drums with high-barrier liners used for tropical destinations, multilayer bags for drier climates—to address these real risks.

    Worker safety and tracer data have become higher profile as regulations increase. We adapted our tracking system early, assigning batch codes that cascade through every receipt, storage, and mixing operation. Auditors can review a lot’s journey from field to tank to drum in a matter of minutes. This level of detail matters to regulators, but also to our own staff when facing abnormal test results or isolated quality events.

    Energy use and waste minimization factor into every investment decision on our plant floor. We invested in solvent recovery units that return more than 95% of our process stream for reuse. Over several years, we’ve gathered performance data that help us fine-tune temperature control, distillation staging, and recycle rates. Our maintenance and engineering teams share these findings through monthly review sessions, keeping environmental impact in balance with product purity and plant uptime.

    From time to time, feedstock variability—driven by yearly weather or geographic shifts in cultivation—pushes us to adapt extraction and purification steps to maintain output quality. It takes attention to detail and access to field-level intelligence about the chemical fingerprint of mint oil supply. Only a manufacturer with skin in the game engages at this level of sourcing and real-time QC adjustment.

    Direct Impact for End Users: What Buyers Notice

    Factories, R&D centers, and brands have grown to expect more than just technical compliance—they look for traceability, actionable support, and real partnership. Customers have told us that with our (+)-Menthol, they can cut down on pre-production blending losses, increase production speed, and avoid downtime caused by batch inconsistencies. QA and QC teams appreciate not having to spend extra hours troubleshooting haze, odor, or performance issues.

    Manufacturers in healthcare benefit from the predictable powder density and tight particle range, making tablet presses and capsule filling lines run more smoothly. In the sensory science world, marketers rely on our product’s clean aromatic profile, a benchmark for new product launches in both food and hygiene sectors. We have built joint testing protocols with major toothpaste and lozenge brands to prove out stability and flavor performance over extended shelf lives—data generated together, not outsourced.

    We know that for most of our partners, speed and certainty mean fewer risks. Our technical support doesn’t come from a call center—it is handled by onsite process chemists and plant engineers who understand the details. Whether troubleshooting a mixing step at a beverage plant or running impurity fingerprinting for a new regulatory submission, our support draws on real manufacturing data.

    With increasing globalization, regulatory standards grow more demanding across all markets. Meeting new updates to US, EU, or APAC regulations is not a job to pass to a file clerk; we train our compliance staff in chemical testing, GMP inspections, and packaging traceability. When a regulatory change occurs, we use on-the-ground data collected by production and QA staff to update procedures and inform partners quickly. These ongoing investments show in customer satisfaction and compliance record.

    Improvements and Innovation Straight from Our Labs and Plant

    Recent years have brought challenges, but also breakthroughs, thanks to our persistent drive to refine each facet of the production chain. We have adopted new inline detection tools for measuring solvent traces, and automated batch feedback systems that sound an alert the minute statistics veer from target thresholds. These constant checks give us milliseconds of early warning—a crucial head start in a facility where batch size and costs run high. Having all key staff on site, empowered to investigate or halt a run, makes a difference that our customers have recognized over the years.

    Our R&D team maintains parallel pilot lines where alternative crystallization agents and seed chemistries are tested for their impact on downstream processability. This grounding in actual plant conditions, rather than lab-scale models, gives us the confidence to scale up innovation without risking bulk runs or making our customers involuntary test cases.

    We also constantly review our downstream impact: how a grind will function in a chewing gum plant, what filtration will mean for milk-based drinks, how menthol’s volatility can affect fragrance balance in hot-filling packaging. Only a hands-on factory team gets immediate feedback from those trials, letting us course-correct and build institutional knowledge right where it matters.

    We also network with international agencies, helping set pharmacopeial updates and jointly investigating safer, more efficient handling and storage protocols. We share anonymized stability and impurity data with academic labs, building a body of evidence that leads to safer, cleaner, and more consistent menthol across the industry.

    Ethics, Environment, and Responsible Sourcing

    Producing (+)-Menthol responsibly means making choices about natural resource use, labor standards, and long-term community impact. From field to drum, we have traced every supply chain partner for adherence to environmental standards and fair labor practices. Workers from local mint-growing communities regularly visit our plant, sharing perspectives that push us toward more sustainable and inclusive sourcing agreements.

    Volatile organic compound emissions, water recycling, and responsible solvent use remain at the top of our management agenda. We report results year by year, making real reductions a matter of public record. Local regulators and independent auditors review our process data, checking for compliance as well as for innovation in energy recovery and safety controls.

    Constant dialogue with both mint farmers and chemical engineers has shown us that alignment on vision and transparency forms the real backbone of product quality. This means working side by side with smallholder farmers, updating agricultural practices, encouraging richer crop rotation, and paying for documented traceability. We know that long-term access to high-quality precursors is only possible where agricultural, ecological, and factory priorities align.

    The Long View: Sustaining Quality in a Changing World

    Change comes steadily in any industrial sector, but especially in ingredients as foundational as menthol. Over several decades, we have seen world demand cycle from household products to pharmaceuticals to new beverage and flavor sectors. Consumer preference may shift, yet the same core needs remain: clean aroma, reliable cooling, traceability, purity. Our commitment as direct manufacturers has not wavered from those tenets, because we live with their impact every day on the factory floor and in the satisfaction or frustration of customers around the world.

    By investing in training, process data, customer engagement, and environmental responsibility, we have carved out a place for (+)-Menthol defined by trust and proven performance. Each challenge, from regulatory compliance to packaging optimization to raw material shifts, sharpens our approach and builds a depth of experience visible in every shipment we send. Our factory’s team knows that excellence does not travel through shortcuts; it grows out of daily effort, adaptability, and the readiness to solve new problems as they arise.

    To anyone seeking a menthol product that goes beyond the commodity, our doors remain open for questions, joint testing, and technical partnership. The field changes, problems evolve, but the essential value of a well-made, carefully monitored, and transparently sourced (+)-Menthol never diminishes.