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Lysozyme Hydrochloride

    • Product Name Lysozyme Hydrochloride
    • Alias Muramidase
    • Einecs 263-969-7
    • Mininmum Order 1 g
    • Factory Site Tengfei Creation Center,55 Jiangjun Avenue, Jiangning District,Nanjing
    • Price Inquiry admin@sinochem-nanjing.com
    • Manufacturer Sinochem Nanjing Corporation
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    502476

    Product Name Lysozyme Hydrochloride
    Chemical Formula C54H85N13O18Cl
    Molecular Weight 1131.3 g/mol
    Appearance White to off-white powder
    Solubility Freely soluble in water
    Ph Range 4.0 - 5.5 (1% solution)
    Source Egg white (commonly derived)
    Storage Conditions Store at 2-8°C
    Cas Number 9068-13-9
    Purity ≥95% (by SDS-PAGE)
    Activity ≥40,000 units/mg
    Odour Odourless
    Stability Stable under recommended storage conditions
    Ec Number 232-713-2
    Application Antibacterial agent

    As an accredited Lysozyme Hydrochloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing Lysozyme Hydrochloride is packaged in a sealed amber glass bottle containing 10 grams, labeled with product details and safety information.
    Shipping Lysozyme Hydrochloride is shipped in tightly sealed, chemical-resistant containers to protect it from moisture and contamination. The package is clearly labeled and handled in accordance with relevant chemical transportation regulations. Typically, it is shipped at ambient temperature, unless otherwise specified, ensuring product stability and safety during transit.
    Storage Lysozyme Hydrochloride should be stored in a tightly sealed container, protected from light, moisture, and excessive heat. Keep it at 2–8°C (refrigerated) for optimal stability. Avoid freezing and store away from incompatible substances, such as strong oxidizing agents. Ensure the storage area is clean, dry, and well-ventilated to prevent contamination and maintain the chemical’s efficacy.
    Application of Lysozyme Hydrochloride

    Applications of Lysozyme Hydrochloride in Industrial Manufacturing

    As a direct manufacturer specializing in Lysozyme Hydrochloride, we supply this bacteriolytic enzyme to downstream industries demanding consistent quality, validated compliance, and traceable supply. Below we detail proven industrial applications, each supported by established regulatory frameworks, production best practices, and specific market product lines.

    1. Protein-Based Food Preservatives (Meat, Dairy, and Egg Processing)

    Food sector processors use Lysozyme Hydrochloride as a natural antimicrobial agent to extend shelf life and control spoilage caused by gram-positive bacteria, especially in high-protein matrices like cheese, cured meats, and liquid egg products. Most manufacturers dose it post-pasteurization, leveraging its heat stability for broad-spectrum bacteriostasis without impairing sensory attributes or nutrition.

    Industry compliance standards

    • EU Regulation (EC) No 1333/2008 on food additives
    • US FDA 21 CFR 184.1557 (Generally Recognized as Safe for egg products and cheese)
    • China GB 2760-2024 Food Safety National Standards for Food Additives
    • Codex Alimentarius Standards for Dairy Products (CODEX STAN 192-1995)

    Typical usage ratio

    • 100–400 mg/kg for dairy cheeses, with adjustments based on bacterial load and storage period
    • 200–500 mg/kg for processed meats and liquid eggs, titrated to target shelf-life goals and specific spoilage risks

    Downstream process integration

    • Added immediately after pasteurization and before packaging in cheese making
    • Incorporated post-cooking/mixing, before casing or portioning in sausage and deli meat production
    • Stirred into liquid egg blends prior to pasteurization and final product filling

    Final product types

    • Hard and semi-hard cheeses (e.g., Emmental, Gouda, Edam)
    • Cooked and cured sausage products
    • Pasteurized and refrigerated liquid egg whites or whole egg blends
    • Fermented and cooked ready-to-eat meats

    2. Pharmaceutical Ingredient for Infectious Disease Treatments

    Pharmaceutical companies formulate Lysozyme Hydrochloride into oral, topical, and parenteral preparations, exploiting its lytic activity and mucolytic function. These applications benefit from its compatibility with GMP standards and established use in formulations targeting respiratory infections, oral ulcers, and wound healing adjuncts, ensuring patient safety and batch uniformity.

    Industry compliance standards

    • European Pharmacopoeia 10.0 (Monograph 0396: Lysozyme hydrochloride)
    • United States Pharmacopeia USP-NF Monograph (lysozyme derived specifications)
    • Japanese Pharmacopoeia (JP XVII Lysozyme Hydrochloride APIs)
    • cGMP ICH Q7/Q9 (Active Pharmaceutical Ingredients manufacturing)

    Typical usage ratio

    • 10–50 mg/tablet or capsule (oral preparations)
    • 0.1–0.5% w/w in topical gels or sprays, adjusted based on required local concentration
    • 1–5 mg/mL for injection, titrated to dosing regimen and clinical application

    Downstream process integration

    • Dissolved in aqueous phase during solution preparations, sterilized by filtration before aseptic filling
    • Blended into excipient matrix during tablet granulation
    • Integrated into gel base at controlled temperatures to prevent enzyme degradation

    Final product types

    • Oral tablets and capsules for upper respiratory infection adjunct therapy
    • Mouthwashes and sprays for oral mucosal lesions
    • Injectable formulations for research or special wound treatments
    • Dermatological creams and gels for wound and burn care

    3. Animal Nutrition & Livestock Feed Additive

    Animal feed producers employ Lysozyme Hydrochloride as a non-antibiotic additive to control pathogenic bacteria in poultry and swine diets, supporting gut health and production performance. Careful formulation ensures the enzyme remains active post-pelleting, aligning with animal feed additive transparency laws and maintaining nutrient absorption efficacy without off-target effects.

    Industry compliance standards

    • EU Regulation (EC) No 1831/2003 on feed additives for animal nutrition
    • US FDA Center for Veterinary Medicine (CVM) Feed Additive Petitions
    • China Ministry of Agriculture Announcement No. 168 Feed Additive Safety
    • FAMI-QS: European Feed Additives and Premixtures Quality System

    Typical usage ratio

    • 15–50 mg/kg feed for poultry and swine, adjusted by species, age, and pathogenic pressure

    Downstream process integration

    • Added at the premix or mineral supplement blending stage
    • Dry blended with base ingredients prior to pelleting; process temperature controlled to preserve enzymatic activity
    • In liquid feeds, dispersed just before final mixing to ensure even distribution

    Final product types

    • Compound feeds for broilers, laying hens, and piglets
    • Pelleted starter, grower, and finisher rations
    • Medicated and health-promoting feed supplements

    4. Beer and Beverage Protein Stabilization

    Industrial brewers and beverage manufacturers use Lysozyme Hydrochloride to prevent protein haze formation and control lactic acid bacteria outgrowth during storage and transit, especially for unpasteurized or specialty beers and low-alcohol beverages. This enzymatic approach allows for extended clarity and shelf life without reliance on synthetic chemical preservatives.

    Industry compliance standards

    • EU Regulation (EC) No 1333/2008 on food additives in beverages
    • US FDA GRAS Notice 702 for use in beer (specific to protein and bacterial stabilization)
    • Japan Food Additive Regulation for brewing aids
    • ISO 22000:2018 Food Safety Management System for beverage processing lines

    Typical usage ratio

    • 3–10 mg/L in finished beer or beverage, adjusted by protein content and risk analysis

    Downstream process integration

    • Added post-fermentation and before filtration or stabilization step
    • In continuous processes, dosed in-line immediately prior to bottling or canning
    • Integrated into tank or batch mixing systems with controlled agitation

    Final product types

    • Draught and bottled beers, including unfiltered craft styles
    • Non-alcoholic and low-alcohol malt beverages
    • Beverages with high-protein plant extracts prone to turbidity

    5. Diagnostic Microbiology and Research Reagents Manufacturing

    Major laboratory reagent manufacturers incorporate Lysozyme Hydrochloride as a cell wall digestion agent in nucleic acid extraction kits and diagnostic test manufacturing, exploiting its specificity for bacterial lysis and downstream compatibility with PCR and culture methodologies. Facilities validate each batch for enzyme activity and low endotoxin to support regulatory submission of IVD medical devices and research reagents.

    Industry compliance standards

    • ISO 13485:2016 Medical Devices – Quality Management for IVD manufacturers
    • US FDA 21 CFR 820 Quality System Regulation (for diagnostics)
    • CE-IVD Marking for European diagnostic reagents
    • OECD Principles of Good Laboratory Practice (GLP) for research-use-only reagents

    Typical usage ratio

    • 0.1–1 mg/mL in lysis buffer, optimized per sample matrix and bacterial cell concentration

    Downstream process integration

    • Formulated as a freeze-dried powder or liquid concentrate in lysis buffer kits
    • Incorporated during bulk reagent preparation for cell lysis protocols
    • Quality tested for activity in simulated sample digestion before kit assembly

    Final product types

    • Bacterial genomic DNA/RNA extraction kits
    • Clinical diagnostic test kits for pathogen detection
    • Microbial identification and sample prep reagents used in pharmaceutical QC labs
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    Certification & Compliance
    More Introduction

    Lysozyme Hydrochloride: A Manufacturer’s Perspective

    The Roots and Promise of Lysozyme Hydrochloride

    As the manufacturer behind Lysozyme Hydrochloride, we see the full journey of this enzyme from the very beginning—starting from high-quality raw material selection to reliable shipment for diverse applications. Lysozyme may have first made a name for itself in food and pharmaceuticals, but we’ve witnessed firsthand how this tried-and-tested ingredient supports a world of industries looking for chemical solutions that address real needs.

    Lysozyme Hydrochloride holds a special place on our production line. This is not a run-of-the-mill item for us. Precision sets the foundation here. We monitor every batch, guided by years modeling processes to remove any shortcuts or guesswork. Each shipment carries a clear fingerprint: high purity, robust stability, and consistently measured enzymatic activity. Whenever clients ask about our standards, we talk about actual lab outcomes—crystal clarity, minimal moisture content, predictable activity units. Our strict standards come from continual customer feedback and practical experience watching how this enzyme behaves during mixing, formulation, and scaling up.

    Why Lysozyme Hydrochloride Matters to Real Manufacturers

    Lysozyme Hydrochloride stands out because it solves genuine problems. Shelf-life and safety remain persistent challenges for food processors. Drug developers and veterinary product formulators keep returning to this enzyme due to its concrete, demonstrable value. This is not a theoretical molecule. Customers depend on it to break down specific bacterial cell walls, especially in environments requiring a non-synthetic approach to preservation and sanitation.

    Every order leaving our facility undergoes rigorous QC. Teams record not just purity, but also performance indicators like clarity, color, and specific enzymatic actions when dissolved in solution. Customers who use egg white lysozyme hydrochloride (model: LZH-20 or similar, depending on year and production run) receive a product that has delivered not only in the lab but also after months in cold and even ambient storage.

    Differences matter in this field. Pure lysozyme is often supplied as a sulfate or chloride salt. We’ve learned over the years that Lysozyme Hydrochloride provides greater solubility in certain aqueous applications and delivers a reliable pH profile for clients who can’t risk variability in the final formulation. There is no hiding from feedback on this: pharmaceutical and food partners will notice any deviation. We have tuned our conversion and drying steps to ensure the final material consistently meets their demands.

    Our Journey: Combining Science with Real-World Demands

    Manufacturing Lysozyme Hydrochloride means listening directly to customers. One poultry vaccine manufacturer contacted us after encountering clumping issues mid-scale due to impurities in their previous supplier’s batch. Our staff traced the issue back to a residual byproduct, which didn’t show up on the supplier’s standard spec sheet. We changed our filtration method and refined the precipitation point to yield the clearest, most filtration-friendly lysozyme hydrochloride available. After switching, the customer experienced no more batch downtime from mixing issues.

    We keep making adjustments like this—listening, learning, and refining. The food industry, for example, pushes us to test for off-odors and aftertastes that might ruin dairy or meat applications. Lysozyme derives from egg whites, but impurities or imperfect enzyme isolation can lead to off-notes, discoloration, and even unwanted allergen traces. We invest in sensory testing and keep detailed records on batches that result in the cleanest, most flavor-neutral product.

    There’s frequent confusion between various lysozyme salt forms. Lysozyme hydrochloride differs from lysozyme sulfate mainly in outcome at the application end. The chloride variant fits seamlessly into liquid-phase systems, so beverage manufacturers and pharma companies have less trouble with settling or precipitation during their quality checks. When customers want both stability and clarity, our feedback is clear: go with the hydrochloride salt.

    Applications: More Than a Single Story

    Lysozyme Hydrochloride crosses borders between food, pharmaceuticals, veterinary healthcare, and even agricultural sectors. Dairy producers incorporate it to extend cheese shelf life without the chemical aftertaste associated with some conventional preservatives. We’ve watched small cheesemakers scale up, relying on our lysozyme to maintain product safety as volumes grow and seasonal variations change milk composition. It doesn’t always grab headlines, but without a stable lysozyme hydrocholoride, smaller operations would face the risk of recalls due to spoilage or inconsistent product safety.

    Pharma partners trust our process because patient outcomes depend on certainty. Every lot we supply comes with certificates showing low endotoxin levels and specific activity measured in MU/mg (typical: ≥20,000 MU/mg). Their focus goes beyond paperwork—veterinary antibiotic alternatives work only if the enzyme remains potent through finished dosage preparation and delivery. Our lab teams work with theirs, troubleshooting everything from reconstitution protocols to long-term stability, so that clinical and veterinary endpoints remain robust.

    The conversation around natural preservatives never really goes away. More clients in plant-based, organic, and clean-label markets seek ingredients with a traceable source and minimal chemical processing. Lysozyme derived from egg white fits this profile, yet it’s our responsibility as a manufacturer to show traceability and full ingredient life-cycle compliance. Certifications, audits, and transparent supply chain management reinforce what we guarantee in every Lysozyme Hydrochloride shipment. These details matter most to auditors and brand owners with strict marketing and regulatory requirements.

    Challenges and Lessons Learned in Real Production

    Not everything runs smoothly. Lysozyme’s enzymatic activity fluctuates based on upstream egg quality, storage conditions, and seasonal shifts. Sometimes, incoming raw eggs have lower protein yields due to climate or feed changes. We forecast and build inventory based on historic data, but every year brings new curveballs. Instead of covering up these realities with advertising, we plan longer lead times and transparent communication with our partners. Production cannot afford hidden surprises—not for us, not for anyone counting on our batches.

    Keeping allergen management tight is non-negotiable. Our process lines work exclusively with avian-source lysozyme. To reassure food and pharma partners, we’ve built clean-in-place and routine allergen residue checks into the production week. It’s our job to catch even trace cross-contamination before product release. Our staff goes beyond regulatory minimum standards in both document control and ongoing verification, recognizing that real safety depends on process habits, not just paperwork.

    Preserving enzyme potency remains a constant test. Water content, thermal stress, and packaging decisions each affect stability. Early in our history, we learned the lesson: a packaging flaw can lead to catastrophic losses from moisture pickup and reduced potency during transit. Our current vacuum-sealing and layered moisture-barrier pouches came directly from those costly lessons. Enzymes freshly shipped maintain higher activity and appearance compared to batches exposed to air leaks or flawed outer cartons.

    We think about transportation every day: whether it’s crossing hot continental interiors in summer or enduring shipping delays at port. Our inbound logistics teams work closely with storage and QA staff, checking every arrival for shifts in appearance or activity. Down the chain, our customers rely on these practical details—shelf life in their warehouse affects their finished goods, so we update them regularly on best practices for storage and handling, based on our own stress-test data.

    Comparing Hydrochloride to Other Lysozyme Forms

    Clients often ask about switching between lysozyme hydrochloride and lysozyme sulfate, especially if they came to us after inconsistent performance from a third-party trader. Our message comes from real lab data and feedback loops. Lysozyme sulfate can work well in some dry blends and feed pre-mixes. For any application involving solution, suspension, or where taste and solubility matter (like pharmaceuticals or beverages), the hydrochloride beats sulfate for clarity, ease of handling, and avoidance of secondary precipitate formation.

    Years ago, one beverage company in the functional drinks market faced repeated haze in their finished product after mid-year formulation changes. Our technical team ran bench-top trials using both lysozyme sulfate and hydrochloride lots, using identical protocols. Lysozyme hydrochloride yielded crystal-clear solutions with stable activity over extended shelf-time, while the sulfate product developed visible haze and a noticeable decline in test activity after only four weeks. Since then, the client converted to hydrochloride exclusively and ultimately avoided costly recalls tied to product complaints.

    Lysozyme in its hydrochloride form also delivers a predictable pH outcome, which often proves critical in sensitive pharma and certain food production environments. Product development and QA teams tell us they prefer materials with demonstrable behavior under varying process conditions. Hydrochloride salt gives that reliability. Differences may seem technical at first glance, but formulation staff don’t forget the time they saved not troubleshooting unexpected changes from upstream raw materials.

    Market Pressures and Sustainability Questions

    Recent years have changed conversations about ingredients. End users look closer at sourcing, asking where each batch comes from, how we manage animal welfare, and what we do about environmental waste. Our supply chain teams buy exclusively from certified egg producers with clear animal health and handling standards. Our company tracks inputs and output streams, aiming for full traceability with no gaps from egg farm to finished, sealed product.

    Lysozyme extraction generates organic byproducts, which we handle responsibly. Our in-plant teams separate and manage these side streams, routing what we can into recovered protein feed or responsible biowaste processing. This practice grew out of necessity and ethical duty, especially as customers themselves moved to more transparent sustainability reporting.

    We face ongoing pressure to maintain price stability against fluctuations in egg supply and ever-changing global shipping costs. Instead of passing costs indiscriminately down the line, we plan production in longer-term blocks, locking in stable prices with trusted suppliers. This approach gives more stable planning windows to the customer side, helping them budget without enduring wild swings or unexpected shortages.

    Solutions Born From Collaboration

    The best solutions in lysozyme production always come from honest cooperation. Customers push us to improve—whether introducing gentler drying methods to preserve activity or fine-tuning packing size for easier use in small batch operations. Several years back, a midsize cheese cooperative flagged issues with inconsistent performance during summer heat waves. Our staff visited, observed their process, and worked alongside their team to recommend on-site storage improvements and cooling routines. By aligning our technical insights with theirs, both parties benefited: fewer returned shipments, higher yield for them, and less waste for us.

    Transparency protects everyone in the current regulatory landscape. We supply detailed COAs, allergen reports, and full traceability for every shipment. Few customers initially request this much documentation, but they quickly recognize its value. Our decades in the enzyme business taught us that those who share both problems and solutions—openly—always fare better in the long run.

    We keep open lines with regulatory bodies and professional associations, attending seminars and sharing real data from our batch tracking. Our team embraces third-party audits rather than viewing them as hurdles. This collaborative approach drives not only product improvement, but also new industry standards in purity, safety, and environmental management.

    The Human Factor in Every Lot

    Robust lysozyme hydrocholoride output comes from more than equipment and documentation. It grows from staff experience, shared learnings, and a team-oriented culture that values trust. Some of our senior staff have spent decades learning the subtle signs that a batch needs a closer look: a slight shift in color or pH, a different aroma hint unnoticed by ordinary sensors. These instincts guide the preventive maintenance, detailed recordkeeping, and day-to-day pride we embed in every lot.

    This human oversight complements our automated controls. Enzyme production relies on skilled hands as much as on calibrated machines. We remind our new hires that what leaves our factory ends up in food, in medication, and in thousands of real lives. Every detail matters: precise weight, accurate labeling, validated cleaning, and transparent documentation. Our culture ties together production, quality, and accountability, giving customers more than just an enzyme on a spreadsheet. They receive work tested and reviewed by real people, responsive to new challenges and dedicated to greater reliability—batch after batch, season after season.

    Lysozyme Hydrochloride in the Future

    Demand for lysozyme hydrochloride continues to expand. Novel food applications, new pharma delivery systems, and more sophisticated quality demands grow each year. Our R&D teams invest in improved extraction methods and alternative source investigations, eyeing the long-term. As manufacturing partners, we anticipate the questions—on allergenicity, sustainability, and functional performance—before they arrive at the audit table.

    We plan our investments on what the field shows, not just what the market forecasts. Facility upgrades, staff training, and raw material partnerships—all hinge on maintaining the kind of reliability, clarity, and trust that only grows through honest communication and decades in the business. Lysozyme Hydrochloride offers proven solutions across more than one field, standing out for direct, practical reasons that manufacturers appreciate when the details count most.

    Every batch we produce represents a chain of people, expertise, and trust that ends with the user—whether in food, pharma, vet, or any specialized field. That’s the perspective you get from looking out our factory window, day in day out, with a clear view of the challenges, rewards, and mutual progress that this essential enzyme continues to deliver.